|
Name |
Accession |
Description |
Interval |
E-value |
| CCDC144C |
pfam14915 |
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ... |
1276-1579 |
9.01e-172 |
|
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ankyrin repeat domain-containing protein 26-like 1 found in eukaryotes. Its function remains unknown, however, it is known to contain a coiled-coil domain which corresponds to this region. The ankyrin repeat which features in this protein is a common amino acid motif.
Pssm-ID: 464371 [Multi-domain] Cd Length: 304 Bit Score: 519.16 E-value: 9.01e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1276 NSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLE 1355
Cdd:pfam14915 1 NCMLQDEIAMLRLEIDTIKNQNQEKEKKYLEDIEILKEKNDDLQKTLKLNEETLTKTVFQYNGQLNVLKAENTMLNSKLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1356 NEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKL 1435
Cdd:pfam14915 81 NEKQNKERLETEVESYRSRLAAAIQDHEQSQTSKRDLELAFQRERDEWLRLQDKMNFDVSNLRDENEILSQQLSKAESKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1436 NSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDA 1515
Cdd:pfam14915 161 NSLENELHRTRDALREKTLLLESVQRDLSQAQCQKKELEHMYQNEQDKVNKYIGKQESLEERLAQLQSENMLLRQQLEDA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 1516 HNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAER 1579
Cdd:pfam14915 241 QNKADAKEKTVIDIQDQFQDIVKKLQAESEKQVLLLEERNKELINECNHLKERLYQYEKEKAER 304
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
44-210 |
1.37e-39 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 149.33 E-value: 1.37e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 44 DRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQC 123
Cdd:COG0666 51 DALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYN 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 124 QEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKA 203
Cdd:COG0666 131 GNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGA 210
|
....*..
gi 2462517863 204 NVNAVDK 210
Cdd:COG0666 211 DVNAKDN 217
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
50-218 |
1.09e-38 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 147.02 E-value: 1.09e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 50 IHKAASAGNVAKVQqiLLLRKNG-LNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKC 128
Cdd:COG0666 91 LHAAARNGDLEIVK--LLLEAGAdVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEI 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 129 ATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAV 208
Cdd:COG0666 169 VKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAK 248
|
170
....*....|
gi 2462517863 209 DKLESSHQLI 218
Cdd:COG0666 249 DKDGLTALLL 258
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
50-210 |
3.58e-32 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 127.76 E-value: 3.58e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 50 IHKAASAGNVAKVQqilLLRKNG--LNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEK 127
Cdd:COG0666 124 LHLAAYNGNLEIVK---LLLEAGadVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLE 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 128 CATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNA 207
Cdd:COG0666 201 IVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAA 280
|
...
gi 2462517863 208 VDK 210
Cdd:COG0666 281 ALL 283
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
44-210 |
2.79e-29 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 119.67 E-value: 2.79e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 44 DRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQC 123
Cdd:COG0666 18 LLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 124 QEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKA 203
Cdd:COG0666 98 GDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGA 177
|
....*..
gi 2462517863 204 NVNAVDK 210
Cdd:COG0666 178 DVNARDN 184
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
84-176 |
7.57e-21 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.63 E-value: 7.57e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 84 LHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHgADPNLADvHGNTALHYAVYNEDISVAT 163
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 2462517863 164 KLLLYDANIEAKN 176
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
50-143 |
2.61e-20 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 87.09 E-value: 2.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 50 IHKAASAGNVAKVQQiLLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDrKCQLNVCDNeNRTALMKAVQCQEEKCA 129
Cdd:pfam12796 1 LHLAAKNGNLELVKL-LLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKDN-GRTALHYAARSGHLEIV 77
|
90
....*....|....
gi 2462517863 130 TILLEHGADPNLAD 143
Cdd:pfam12796 78 KLLLEKGADINVKD 91
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
50-183 |
3.09e-20 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 93.09 E-value: 3.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 50 IHKAASAGNVAKVQqiLLLrKNG--LNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEK 127
Cdd:COG0666 157 LHLAAANGNLEIVK--LLL-EAGadVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLE 233
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462517863 128 CATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPL 183
Cdd:COG0666 234 IVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
65-210 |
1.41e-18 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 88.09 E-value: 1.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 65 ILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADV 144
Cdd:COG0666 6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462517863 145 HGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDK 210
Cdd:COG0666 86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDN 151
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1087-1624 |
2.42e-15 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 82.15 E-value: 2.42e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1087 LLKIQDAALSCERLL-ELKKNHCELLTVKiKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRR 1165
Cdd:pfam01576 14 LQKVKERQQKAESELkELEKKHQQLCEEK-NALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1166 NADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVvqerNDAQRQLSREQNARMLQDGILTNHL 1245
Cdd:pfam01576 93 QLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLL----EDQNSKLSKERKLLEERISEFTSNL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1246 SKQKE---------------IEMAQKKMNSENSHSHEEEK---DLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEkkcfed 1307
Cdd:pfam01576 169 AEEEEkakslsklknkheamISDLEERLKKEEKGRQELEKakrKLEGESTDLQEQIAELQAQIAELRAQLAKKE------ 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1308 lkivkeknEDLQKTIKQNEETLTQTiSQYNGRLSVLTAENAMLNSKLENEKQSKER-------LEAEVESYHSRLAAAIH 1380
Cdd:pfam01576 243 --------EELQAALARLEEETAQK-NNALKKIRELEAQISELQEDLESERAARNKaekqrrdLGEELEALKTELEDTLD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1381 DR--DQSETSKRELELA-FQRARDECSRLQDKMNFDVSNLKDNN-EILSQQLFKTESKLNSLEiefhHTRDALREKTLGL 1456
Cdd:pfam01576 314 TTaaQQELRSKREQEVTeLKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKRNKANLE----KAKQALESENAEL 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1457 ERVQKDLSQ----TQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQ 1532
Cdd:pfam01576 390 QAELRTLQQakqdSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQ 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1533 FHAiVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQ----SMSEASLEVTS 1608
Cdd:pfam01576 470 LQD-TQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLeedaGTLEALEEGKK 548
|
570
....*....|....*.
gi 2462517863 1609 RYRINLEDETQDLKKK 1624
Cdd:pfam01576 549 RLQRELEALTQQLEEK 564
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1103-1539 |
3.07e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 75.06 E-value: 3.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1103 LKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKE 1182
Cdd:TIGR04523 194 NKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1183 EQYRKEVEVKQQLELSLQTLEMEL------------RTVKSNLNQVVQERNDAQRQLSR-EQNARMLQDGIL-------- 1241
Cdd:TIGR04523 274 KELEQNNKKIKELEKQLNQLKSEIsdlnnqkeqdwnKELKSELKNQEKKLEEIQNQISQnNKIISQLNEQISqlkkeltn 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1242 --TNHLSKQKEIEMAQKKMNSENshshEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKcfedLKIVKEKNEDLQ 1319
Cdd:TIGR04523 354 seSENSEKQRELEEKQNEIEKLK----KENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ----IKKLQQEKELLE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1320 KTIKQneetLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSE---TSKRELELAF 1396
Cdd:TIGR04523 426 KEIER----LKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQkelKSKEKELKKL 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1397 QRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLE-----IEFHHTRDALREKTLG-------LERVQKDLS 1464
Cdd:TIGR04523 502 NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEdelnkDDFELKKENLEKEIDEknkeieeLKQTQKSLK 581
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462517863 1465 QTQCQMKEMEQKYQNEQVKVNK----YIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQK 1539
Cdd:TIGR04523 582 KKQEEKQELIDQKEKEKKDLIKeieeKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
843-1638 |
3.70e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.09 E-value: 3.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 843 SANNYKSMEPELENVRSSpprgdRTSKVSLKEELQQDMQRFKNEIGMLKVEFQALEKEKVQLQKEVEeerkkhrnnemEV 922
Cdd:TIGR02168 230 LVLRLEELREELEELQEE-----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY-----------AL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 923 SANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKEN---KEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKA 999
Cdd:TIGR02168 294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDelaEELAELEEKLEELKEELESLEAELEELEAELEELESR 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1000 SlltgGLLQVDDDSSLSEIDEdegrptkkTSNEKNKVKNQIQSMDD-VDDLTQSSETASEDcelphssyknfmllIEQLG 1078
Cdd:TIGR02168 374 L----EELEEQLETLRSKVAQ--------LELQIASLNNEIERLEArLERLEDRRERLQQE--------------IEELL 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1079 MEckdsvslLKIQDAALSCERLLELKKnhcelltvKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLN 1158
Cdd:TIGR02168 428 KK-------LEEAELKELQAELEELEE--------ELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1159 QEEEKRRNADTLYEKIREQLRRK----------------EEQYRKEVEVkqQLELSLQTLEMElrtvksNLNQVVQ---- 1218
Cdd:TIGR02168 493 SLERLQENLEGFSEGVKALLKNQsglsgilgvlselisvDEGYEAAIEA--ALGGRLQAVVVE------NLNAAKKaiaf 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1219 -ERNDAQRQL-------------SREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEkDLSHKNSMLQEEIA 1284
Cdd:TIGR02168 565 lKQNELGRVTflpldsikgteiqGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD-DLDNALELAKKLRP 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1285 MLR---LEIDTIKN---------------QNQEKE-KKCFEDLKIVKEKNEDLQKTIKQNEETLtqtiSQYNGRLSVLTA 1345
Cdd:TIGR02168 644 GYRivtLDGDLVRPggvitggsaktnssiLERRREiEELEEKIEELEEKIAELEKALAELRKEL----EELEEELEQLRK 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1346 ENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNfdvsNLKDNNEILS 1425
Cdd:TIGR02168 720 ELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLK 795
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1426 QQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSEn 1505
Cdd:TIGR02168 796 EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE- 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1506 mllrqqLDDAHNKADNKEKTVINIQDQFHAIVQKLQAesekqsllLEERNKELISECNHLKERQYQYENEKAEREVVVRQ 1585
Cdd:TIGR02168 875 ------LEALLNERASLEEALALLRSELEELSEELRE--------LESKRSELRRELEELREKLAQLELRLEGLEVRIDN 940
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 1586 LQQELADTLkkqsmsEASLEVTSRYRINLEDETQDLKKKLGQIRNQ-PELGSVD 1638
Cdd:TIGR02168 941 LQERLSEEY------SLTLEEAEALENKIEDDEEEARRRLKRLENKiKELGPVN 988
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
9-220 |
6.40e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 72.72 E-value: 6.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 9 GESPLgSFARRRRSSAGGGGEPGEGAYsqPGYHVRDRDlGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLAC 88
Cdd:PHA02875 35 GISPI-KLAMKFRDSEAIKLLMKHGAI--PDVKYPDIE-SELHDAVEEGDVKAVEELLDLGKFADDVFYKDGMTPLHLAT 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 89 ANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLY 168
Cdd:PHA02875 111 ILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDS 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2462517863 169 DANIEAKNKD-DLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISE 220
Cdd:PHA02875 191 GANIDYFGKNgCVAALCYAIENNKIDIVRLFIKRGADCNIMFMIEGEECTILD 243
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
54-210 |
3.52e-12 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 70.46 E-value: 3.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 54 ASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACAN--GHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATI 131
Cdd:PHA03100 80 YNLTDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSDGENLLHLYLESNKIDLKIL 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 132 ------------------LLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQ 193
Cdd:PHA03100 160 kllidkgvdinaknrvnyLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKE 239
|
170
....*....|....*..
gi 2462517863 194 MVEFLIKKKANVNAVDK 210
Cdd:PHA03100 240 IFKLLLNNGPSIKTIIE 256
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1087-1637 |
4.31e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.51 E-value: 4.31e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1087 LLKIQDAALSCERL---LELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEK 1163
Cdd:COG1196 231 LLKLRELEAELEELeaeLEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEER 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1164 RRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQV-------VQERNDAQRQLSREQNARML 1236
Cdd:COG1196 311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAeealleaEAELAEAEEELEELAEELLE 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1237 QDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEkkcfEDLKIVKEKNE 1316
Cdd:COG1196 391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE----EEEEALLELLA 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1317 DLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAf 1396
Cdd:COG1196 467 ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA- 545
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1397 qrardecSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEfhhtRDALREKTLGLERVQKDLSQTQCQMKEMEQK 1476
Cdd:COG1196 546 -------AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR----ARAALAAALARGAIGAAVDLVASDLREADAR 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1477 Y---QNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQS---LL 1550
Cdd:COG1196 615 YyvlGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAeeeLE 694
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1551 LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRN 1630
Cdd:COG1196 695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774
|
....*...
gi 2462517863 1631 QPE-LGSV 1637
Cdd:COG1196 775 EIEaLGPV 782
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1179-1602 |
1.85e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.33 E-value: 1.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1179 RRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSReqnarmlqdgiltnhlsKQKEIEMAQKKM 1258
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGE-----------------IEKEIEQLEQEE 732
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1259 NSENshshEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEkkcfEDLKIVKEKNEDLqktikqneetltqtisqyng 1338
Cdd:TIGR02169 733 EKLK----ERLEELEEDLSSLEQEIENVKSELKELEARIEELE----EDLHKLEEALNDL-------------------- 784
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1339 rlsvltaENAMLNSKLENEKQSKErleaEVESYHSRLAAAIHDRDQsETSKRELELAFqrARDECSRLQDKMNfdvsNLK 1418
Cdd:TIGR02169 785 -------EARLSHSRIPEIQAELS----KLEEEVSRIEARLREIEQ-KLNRLTLEKEY--LEKEIQELQEQRI----DLK 846
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1419 DNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERL 1498
Cdd:TIGR02169 847 EQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1499 SQLQSENmllrQQLDDAhNKADNKEKTVINIQDQFHAIVQKLQAESEKqsllLEERNKELISECNHLKERQYQYENEKAE 1578
Cdd:TIGR02169 927 EALEEEL----SEIEDP-KGEDEEIPEEELSLEDVQAELQRVEEEIRA----LEPVNMLAIQEYEEVLKRLDELKEKRAK 997
|
410 420
....*....|....*....|....*.
gi 2462517863 1579 REVVVRQLQQELA--DTLKKQSMSEA 1602
Cdd:TIGR02169 998 LEEERKAILERIEeyEKKKREVFMEA 1023
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
94-212 |
2.03e-11 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 68.51 E-value: 2.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 94 EVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATI---LLEHGADPNLADVHGNTALHYAVYNED-ISVATKLLLYD 169
Cdd:PHA03095 28 EEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEKVKDIvrlLLEAGADVNAPERCGFTPLHLYLYNATtLDVIKLLIKAG 107
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2462517863 170 ANIEAKNKDDLTPLLLAVSGK--KQQMVEFLIKKKANVNAVDKLE 212
Cdd:PHA03095 108 ADVNAKDKVGRTPLHVYLSGFniNPKVIRLLLRKGADVNALDLYG 152
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
75-209 |
6.10e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 66.83 E-value: 6.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 75 DRDKMNrTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAV 154
Cdd:PHA02878 164 DRHKGN-TALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISV 242
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462517863 155 -YNEDISVATKLLLYDANIEAKNK-DDLTPLLLAVsgKKQQMVEFLIKKKANVNAVD 209
Cdd:PHA02878 243 gYCKDYDILKLLLEHGVDVNAKSYiLGLTALHSSI--KSERKLKLLLEYGADINSLN 297
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1074-1629 |
7.67e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 67.45 E-value: 7.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1074 IEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKS----QLEHQKVEWERE 1149
Cdd:pfam15921 278 VEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEdkieELEKQLVLANSE 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1150 LCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQL---------------------ELSLQTLEMELRT 1208
Cdd:pfam15921 358 LTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLwdrdtgnsitidhlrrelddrNMEVQRLEALLKA 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1209 VKSNlnqvVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEI------EMAQKKMNSENShsheeEKDLSHKNSMLQE- 1281
Cdd:pfam15921 438 MKSE----CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMlrkvveELTAKKMTLESS-----ERTVSDLTASLQEk 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1282 ---------EIAMLRLEIDT-------IKNQN---QEKEKKCfEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSV 1342
Cdd:pfam15921 509 eraieatnaEITKLRSRVDLklqelqhLKNEGdhlRNVQTEC-EALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGA 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1343 LTAENAMLNSK-------------LENEKQSKER-LEAEV---ESYHSRLAAAIHDRDQS----ETSKRELELAFQRARD 1401
Cdd:pfam15921 588 MQVEKAQLEKEindrrlelqefkiLKDKKDAKIReLEARVsdlELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRN 667
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1402 ECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALR----------------EKTLGLERVQKDLSQ 1465
Cdd:pfam15921 668 ELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKsmegsdghamkvamgmQKQITAKRGQIDALQ 747
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1466 TQCQMKEMEQKYQNEQV-----KVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQF---HAIV 1537
Cdd:pfam15921 748 SKIQFLEEAMTNANKEKhflkeEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFaecQDII 827
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1538 QKLQAESEKQSLLLEERNKEL----ISECNHLKERQYQYENEKAEREVVVRQlqQELADTLKKQSMSEASLEvtsryrin 1613
Cdd:pfam15921 828 QRQEQESVRLKLQHTLDVKELqgpgYTSNSSMKPRLLQPASFTRTHSNVPSS--QSTASFLSHHSRKTNALK-------- 897
|
650
....*....|....*.
gi 2462517863 1614 lEDETQDLKKKLGQIR 1629
Cdd:pfam15921 898 -EDPTRDLKQLLQELR 912
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
66-280 |
1.31e-10 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 66.43 E-value: 1.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 66 LLLRKNGLNDRDKMNRTALHLAcANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVH 145
Cdd:PLN03192 512 LLGDNGGEHDDPNMASNLLTVA-STGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDAN 590
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 146 GNTAL-------HYAVYN------------------------EDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQM 194
Cdd:PLN03192 591 GNTALwnaisakHHKIFRilyhfasisdphaagdllctaakrNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDM 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 195 VEFLIKKKANVNAVDKLES-SHQLISEYKEERIPKHSSQNSNSVDESSEDSLSRLSGKPGVDDSwpTSDDEdlnfdtKNV 273
Cdd:PLN03192 671 VRLLIMNGADVDKANTDDDfSPTELRELLQKRELGHSITIVDSVPADEPDLGRDGGSRPGRLQG--TSSDN------QCR 742
|
....*..
gi 2462517863 274 PKPSLAK 280
Cdd:PLN03192 743 PRVSIYK 749
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1125-1629 |
1.31e-10 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 66.53 E-value: 1.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1125 LQRELSETKEIKSQLEhqKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLrrKEEQYRKEVEVKQQLELSLQTLEM 1204
Cdd:TIGR00618 158 LKAKSKEKKELLMNLF--PLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLC--TPCMPDTYHERKQVLEKELKHLRE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1205 ELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGI------LTNHLSKQKEIEMA------------------------ 1254
Cdd:TIGR00618 234 ALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIeelraqEAVLEETQERINRArkaaplaahikavtqieqqaqrih 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1255 ---QKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQ 1331
Cdd:TIGR00618 314 telQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQ 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1332 TISQYNGRLSVLTAENAM---LNSKLENEKQSKERLEAEVE---SYHSRLAAAIHDRDQSET-SKRELELAFQRARDECS 1404
Cdd:TIGR00618 394 KLQSLCKELDILQREQATidtRTSAFRDLQGQLAHAKKQQElqqRYAELCAAAITCTAQCEKlEKIHLQESAQSLKEREQ 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1405 RLQDKMNF--DVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREktlglervqkdLSQTQCQMKEMEQKYQNEQV 1482
Cdd:TIGR00618 474 QLQTKEQIhlQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDN-----------PGPLTRRMQRGEQTYAQLET 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1483 KVNKYIGKQESVEERLSQLQSENMLLRQQLdDAHNKADNKEKTVINIQDQFHAIVQKL---QAESEKQSLLLEERNKELI 1559
Cdd:TIGR00618 543 SEEDVYHQLTSERKQRASLKEQMQEIQQSF-SILTQCDNRSKEDIPNLQNITVRLQDLtekLSEAEDMLACEQHALLRKL 621
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462517863 1560 SECNHLKERQyQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTS------RYRINLEDETQDLKKKLGQIR 1629
Cdd:TIGR00618 622 QPEQDLQDVR-LHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVlpkellASRQLALQKMQSEKEQLTYWK 696
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1299-1622 |
5.31e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.69 E-value: 5.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1299 EKEKKCFEDLKIVKEKNEDLQKTI--------KQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1370
Cdd:TIGR02168 206 ERQAEKAERYKELKAELRELELALlvlrleelREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1371 YHSRLAAAihdrdQSETSKRELELAFQRARDEcsrlqdkmnfdvsNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALR 1450
Cdd:TIGR02168 286 LQKELYAL-----ANEISRLEQQKQILRERLA-------------NLERQLEELEAQLEELESKLDELAEELAELEEKLE 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1451 EKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAhnkADNKEKTVINIQ 1530
Cdd:TIGR02168 348 ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL---EDRRERLQQEIE 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1531 DQfhaivqkLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRY 1610
Cdd:TIGR02168 425 EL-------LKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERL 497
|
330
....*....|..
gi 2462517863 1611 RINLEDETQDLK 1622
Cdd:TIGR02168 498 QENLEGFSEGVK 509
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
39-214 |
5.86e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 64.31 E-value: 5.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 39 GYHVRDRDLGK---IHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGH-PEVVTLLVDRKCQLNVCDNENR 114
Cdd:PHA02876 263 GFSVNSIDDCKntpLHHASQAPSLSRLVPKLLERGADVNAKNIKGETPLYLMAKNGYdTENIRTLIMLGADVNAADRLYI 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 115 TALMKAVQCQEEKCATI-LLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQ 193
Cdd:PHA02876 343 TPLHQASTLDRNKDIVItLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTNPY 422
|
170 180
....*....|....*....|..
gi 2462517863 194 M-VEFLIKKKANVNAVDKLESS 214
Cdd:PHA02876 423 MsVKTLIDRGANVNSKNKDLST 444
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
125-210 |
6.79e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 63.36 E-value: 6.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 125 EEKCATILLEHGADPNLADVH-GNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKA 203
Cdd:PHA02878 146 EAEITKLLLSYGADINMKDRHkGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGA 225
|
....*..
gi 2462517863 204 NVNAVDK 210
Cdd:PHA02878 226 STDARDK 232
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
50-214 |
1.24e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 62.38 E-value: 1.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 50 IHKAASAGNVAKVQQILllrKNG--LNDRDKMNRTALHLACANGH-----PEVVTLLVDRKCQLNVCDNENRTALMKAVQ 122
Cdd:PHA03100 39 LYLAKEARNIDVVKILL---DNGadINSSTKNNSTPLHYLSNIKYnltdvKEIVKLLLEYGANVNAPDNNGITPLLYAIS 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 123 CQEEKCATI--LLEHGADPNLADVHGNTALHYAV---------------YNEDISVATK---LLLYDANIEAKNKDDLTP 182
Cdd:PHA03100 116 KKSNSYSIVeyLLDNGANVNIKNSDGENLLHLYLesnkidlkilkllidKGVDINAKNRvnyLLSYGVPINIKDVYGFTP 195
|
170 180 190
....*....|....*....|....*....|..
gi 2462517863 183 LLLAVSGKKQQMVEFLIKKKANVNAVDKLESS 214
Cdd:PHA03100 196 LHYAVYNNNPEFVKYLLDLGANPNLVNKYGDT 227
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
55-179 |
1.42e-09 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 62.35 E-value: 1.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 55 SAGNVAKVqqILLLRKNG--LNDRDKMNRTALHL-ACANGHPEVVTLLVDRKCQLNVCDNENRTALMK--AVQCQEEKCA 129
Cdd:PHA03095 58 SSEKVKDI--VRLLLEAGadVNAPERCGFTPLHLyLYNATTLDVIKLLIKAGADVNAKDKVGRTPLHVylSGFNINPKVI 135
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2462517863 130 TILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDD 179
Cdd:PHA03095 136 RLLLRKGADVNALDLYGMTPLAVLLKSRNANVELLRLLIDAGADVYAVDD 185
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1176-1504 |
2.44e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.39 E-value: 2.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1176 EQLRRKEEQYRKEVEvkqQLELSLQTLEMELRTVKSNLNQVVQERNDAQR--QLSREqnarmLQDGILTNHLsKQKEIEM 1253
Cdd:TIGR02169 166 AEFDRKKEKALEELE---EVEENIERLDLIIDEKRQQLERLRREREKAERyqALLKE-----KREYEGYELL-KEKEALE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1254 AQKKmnsenshshEEEKDLSHknsmLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTI 1333
Cdd:TIGR02169 237 RQKE---------AIERQLAS----LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEI 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1334 SQ-------YNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAI----HDRDQSETSKRELE---LAFQRA 1399
Cdd:TIGR02169 304 ASlersiaeKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTeeyaELKEELEDLRAELEevdKEFAET 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1400 RDECSRLQDKM----------NFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQ 1469
Cdd:TIGR02169 384 RDELKDYREKLeklkreinelKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD 463
|
330 340 350
....*....|....*....|....*....|....*
gi 2462517863 1470 MKEMEQKYQNEQVKVNKyigkqesVEERLSQLQSE 1504
Cdd:TIGR02169 464 LSKYEQELYDLKEEYDR-------VEKELSKLQRE 491
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
50-211 |
2.61e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 62.00 E-value: 2.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 50 IHKAASAGNvAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNvcdnENRTALMKAVQCQEEKCA 129
Cdd:PHA02876 182 IHYAAERGN-AKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNIN----KNDLSLLKAIRNEDLETS 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 130 TILLEHGADPNLADVHGNTALHYAVYNEDIS-VATKLLLYDANIEAKNKDDLTPL-LLAVSGKKQQMVEFLIKKKANVNA 207
Cdd:PHA02876 257 LLLYDAGFSVNSIDDCKNTPLHHASQAPSLSrLVPKLLERGADVNAKNIKGETPLyLMAKNGYDTENIRTLIMLGADVNA 336
|
....
gi 2462517863 208 VDKL 211
Cdd:PHA02876 337 ADRL 340
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
50-209 |
3.92e-09 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 61.19 E-value: 3.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 50 IHKAASAGNVAKVQQiLLLRKNG-LNDRDKMNRTALH--LACANGHPEVVTLLVDRKCQLNVCDNENRT---ALMKAVQC 123
Cdd:PHA03095 87 LHLYLYNATTLDVIK-LLIKAGAdVNAKDKVGRTPLHvyLSGFNINPKVIRLLLRKGADVNALDLYGMTplaVLLKSRNA 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 124 QEE----------------------------------KCATILLEHGADPNLADVHGNTALHYAVYNEDI--SVATKLLL 167
Cdd:PHA03095 166 NVEllrllidagadvyavddrfrsllhhhlqsfkpraRIVRELIRAGCDPAATDMLGNTPLHSMATGSSCkrSLVLPLLI 245
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2462517863 168 YDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVD 209
Cdd:PHA03095 246 AGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVS 287
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
129-282 |
9.01e-09 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 60.30 E-value: 9.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 129 ATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVeflikkkanvnav 208
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVV------------- 164
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 209 dklesshQLISEYKEEripkHSSQNSNSVDESsedslsrLSGKPGVDDSWPTSDDEDlnfDTKNVPKPSLAKLM 282
Cdd:PTZ00322 165 -------QLLSRHSQC----HFELGANAKPDS-------FTGKPPSLEDSPISSHHP---DFSAVPQPMMGSLI 217
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1161-1465 |
9.02e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.34 E-value: 9.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1161 EEKRRNADTL---------YEKIREQLRRKEEQYRkeVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQ 1231
Cdd:COG1196 196 GELERQLEPLerqaekaerYRELKEELKELEAELL--LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1232 NARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKcFEDLKIV 1311
Cdd:COG1196 274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE-LEEAEEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1312 KEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRE 1391
Cdd:COG1196 353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 1392 LELAFQRARDECSRLQDKMNfDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQ 1465
Cdd:COG1196 433 LEEEEEEEEEALEEAAEEEA-ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1102-1425 |
1.06e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.46 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1102 ELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRK 1181
Cdd:TIGR02168 221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1182 EEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLsreqnarmlqDGILTNHLSKQKEIEMAQKKMnsE 1261
Cdd:TIGR02168 301 EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL----------EELKEELESLEAELEELEAEL--E 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1262 NSHSHEEEKDLSHKNsmLQEEIAMLRLEIDTIKNQNQEKEKKcfedLKIVKEKNEDLQKTIKQNEETLTqtisqyNGRLS 1341
Cdd:TIGR02168 369 ELESRLEELEEQLET--LRSKVAQLELQIASLNNEIERLEAR----LERLEDRRERLQQEIEELLKKLE------EAELK 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1342 VLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQsetSKRELELAFQRARDECSRLQDKMNF--DVSNLKD 1419
Cdd:TIGR02168 437 ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA---AERELAQLQARLDSLERLQENLEGFseGVKALLK 513
|
....*.
gi 2462517863 1420 NNEILS 1425
Cdd:TIGR02168 514 NQSGLS 519
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1092-1605 |
2.60e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 58.90 E-value: 2.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1092 DAALSCERLLELKKNHCELLTVKIKKMEDK-----VNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRN 1166
Cdd:PRK02224 173 DARLGVERVLSDQRGSLDQLKAQIEEKEEKdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1167 ADTLYEKIREqLR-------RKEEQYRKEVEVKQQLELSLQTLEMELRTvKSNLNQVVQERNDAQRQ-LSREQNArmLQD 1238
Cdd:PRK02224 253 LETLEAEIED-LRetiaeteREREELAEEVRDLRERLEELEEERDDLLA-EAGLDDADAEAVEARREeLEDRDEE--LRD 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1239 GILtnhlskqkEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKnqnqekekkcfEDLKIVKEKNEDL 1318
Cdd:PRK02224 329 RLE--------ECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAR-----------EAVEDRREEIEEL 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1319 QKTIKQNEETLTQTISQYNGrlsvLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAA---------------IHDR- 1382
Cdd:PRK02224 390 EEEIEELRERFGDAPVDLGN----AEDFLEELREERDELREREAELEATLRTARERVEEAealleagkcpecgqpVEGSp 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1383 -----DQSETSKRELELAFQRARDECSRLQDKMNfdvsnlkdnneiLSQQLFKTESKLNSLE---------IEFHHTRDA 1448
Cdd:PRK02224 466 hvetiEEDRERVEELEAELEDLEEEVEEVEERLE------------RAEDLVEAEDRIERLEerredleelIAERRETIE 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1449 LREKTLGLERVQKDLSQTQCQMK-----EMEQKYQNEQVKVNKYIGKQESVEERLSQLQSenmlLRQQLDDAHNKADN-- 1521
Cdd:PRK02224 534 EKRERAEELRERAAELEAEAEEKreaaaEAEEEAEEAREEVAELNSKLAELKERIESLER----IRTLLAAIADAEDEie 609
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1522 ----KEKTVINIQDQFHaivQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAERevvVRQLQQELADTLKKQ 1597
Cdd:PRK02224 610 rlreKREALAELNDERR---ERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEK---LDELREERDDLQAEI 683
|
....*...
gi 2462517863 1598 SMSEASLE 1605
Cdd:PRK02224 684 GAVENELE 691
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
73-218 |
3.25e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 58.05 E-value: 3.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 73 LNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHY 152
Cdd:PHA02874 117 VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHN 196
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462517863 153 AVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSgKKQQMVEFLIKKKA-NVNAVDKLESSHQLI 218
Cdd:PHA02874 197 AAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAII-HNRSAIELLINNASiNDQDIDGSTPLHHAI 262
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
150-210 |
4.81e-08 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 52.04 E-value: 4.81e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462517863 150 LHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIkKKANVNAVDK 210
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL-EHADVNLKDN 60
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1074-1606 |
7.16e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.44 E-value: 7.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1074 IEQLGMECKDSVSLLkIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQrelSETKEIKSQLEHQKVEWERELCSL 1153
Cdd:pfam15921 247 LEALKSESQNKIELL-LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQ---SQLEIIQEQARNQNSMYMRQLSDL 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1154 RFSLNQEEEKRRNADTLYEKIREQL--------------RRKEEQYRKEV----EVKQQLELSLQTLEMELRTVKS---- 1211
Cdd:pfam15921 323 ESTVSQLRSELREAKRMYEDKIEELekqlvlanselteaRTERDQFSQESgnldDQLQKLLADLHKREKELSLEKEqnkr 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1212 -------------NLNQVVQERN---------------DAQRQLSRE------QNARMLQDGILTNHLSKQKEI------ 1251
Cdd:pfam15921 403 lwdrdtgnsitidHLRRELDDRNmevqrleallkamksECQGQMERQmaaiqgKNESLEKVSSLTAQLESTKEMlrkvve 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1252 EMAQKKMNSENShsheeEKDLSHKNSMLQE----------EIAMLRLEIDT-------IKNQN---QEKEKKCfEDLKIV 1311
Cdd:pfam15921 483 ELTAKKMTLESS-----ERTVSDLTASLQEkeraieatnaEITKLRSRVDLklqelqhLKNEGdhlRNVQTEC-EALKLQ 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1312 KEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEvesyhsrlaaaihdRDQSETSKRE 1391
Cdd:pfam15921 557 MAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKIL--------------KDKKDAKIRE 622
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1392 LELAFQRARDECSRLQDKMN---FDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKT-----------LGLE 1457
Cdd:pfam15921 623 LEARVSDLELEKVKLVNAGSerlRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSeemetttnklkMQLK 702
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1458 RVQKDLSQTQCQMKEMEQKyQNEQVKVNKYIGKQESVEE-RLSQLQSENMLLRQQLDDAhnkadNKEKtviniqdqfHAI 1536
Cdd:pfam15921 703 SAQSELEQTRNTLKSMEGS-DGHAMKVAMGMQKQITAKRgQIDALQSKIQFLEEAMTNA-----NKEK---------HFL 767
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462517863 1537 VQKLQAESEKQSLLLEERNKeLISECNHLKERQYQYENEKAEREVVVRQLQQELA---DTLKKQSMSEASLEV 1606
Cdd:pfam15921 768 KEEKNKLSQELSTVATEKNK-MAGELEVLRSQERRLKEKVANMEVALDKASLQFAecqDIIQRQEQESVRLKL 839
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
113-166 |
2.39e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 48.81 E-value: 2.39e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 113 NRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLL 166
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1147-1378 |
4.90e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 4.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1147 ERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYrkevevkQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQ 1226
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-------AALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1227 LSREQN--ARMLQDgiltnhLSKQKEIEMAQKKMNSENSHSHEEEKD-LSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKK 1303
Cdd:COG4942 99 LEAQKEelAELLRA------LYRLGRQPPLALLLSPEDFLDAVRRLQyLKYLAPARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462517863 1304 cFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAA 1378
Cdd:COG4942 173 -RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1105-1331 |
5.79e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.68 E-value: 5.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1105 KNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQ 1184
Cdd:TIGR02168 795 KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE 874
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1185 YRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLS--REQNARM-LQDGILTNHLSKQKEIEMAQKKMNSE 1261
Cdd:TIGR02168 875 LEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEelREKLAQLeLRLEGLEVRIDNLQERLSEEYSLTLE 954
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462517863 1262 NSHSHEEEKDLSHKNsmLQEEIAMLRLEIDTIKNQNQ------EKEKKCFEDLKivKEKnEDLQKTIKQNEETLTQ 1331
Cdd:TIGR02168 955 EAEALENKIEDDEEE--ARRRLKRLENKIKELGPVNLaaieeyEELKERYDFLT--AQK-EDLTEAKETLEEAIEE 1025
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
132-186 |
6.38e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 47.73 E-value: 6.38e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2462517863 132 LLEHG-ADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLA 186
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1353-1629 |
6.65e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.56 E-value: 6.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1353 KLENEKQSKERLE---AEVESYHSRLA-----AAIHDRDQSETSKRELELAFQRaRDECSRLQDKMNFDVSNLKDNNEIL 1424
Cdd:COG1196 180 KLEATEENLERLEdilGELERQLEPLErqaekAERYRELKEELKELEAELLLLK-LRELEAELEELEAELEELEAELEEL 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1425 SQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTqcqmkEMEQKYQNEQvkvnkyigkQESVEERLSQLQSE 1504
Cdd:COG1196 259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL-----EQDIARLEER---------RRELEERLEELEEE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1505 NMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISEcNHLKERQYQYENEKAEREVVVR 1584
Cdd:COG1196 325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL-EELAEELLEALRAAAELAAQLE 403
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 2462517863 1585 QLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIR 1629
Cdd:COG1196 404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
66-210 |
8.41e-07 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 53.49 E-value: 8.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 66 LLLRK-NGLNDRDKMNRTALHLACANGHP--EVVTLLVDRKCQLNVCDNENRTAL-MKAVQCQeekCATI----LLEHGA 137
Cdd:PHA03095 172 LLIDAgADVYAVDDRFRSLLHHHLQSFKPraRIVRELIRAGCDPAATDMLGNTPLhSMATGSS---CKRSlvlpLLIAGI 248
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 138 DPNLADVHGNTALHYA-VYNEDISVAtKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDK 210
Cdd:PHA03095 249 SINARNRYGQTPLHYAaVFNNPRACR-RLIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAKNPSAETVAA 321
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
121-292 |
1.01e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 53.53 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 121 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIK 200
Cdd:PHA02876 153 IQQDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIID 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 201 KKANVNAVDkLESSHQLISEYKEERIPKHSSQNS-NSVDESSEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLA 279
Cdd:PHA02876 233 NRSNINKND-LSLLKAIRNEDLETSLLLYDAGFSvNSIDDCKNTPLHHASQAPSLSRLVPKLLERGADVNAKNIKGETPL 311
|
170
....*....|...
gi 2462517863 280 KLMTASQQSRKNL 292
Cdd:PHA02876 312 YLMAKNGYDTENI 324
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1174-1631 |
1.03e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.57 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1174 IREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDaqrqLSREQNARMLQDGILTNHLSKQKEiem 1253
Cdd:pfam05483 97 IEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKD----LIKENNATRHLCNLLKETCARSAE--- 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1254 AQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDtikNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTI 1333
Cdd:pfam05483 170 KTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAE---NARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLL 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1334 SQYNGRlsvltaENAM--LNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMN 1411
Cdd:pfam05483 247 IQITEK------ENKMkdLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQ 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1412 F---DVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALrEKTLGLERVQKDLSQTQCQMKEME-QKYQNEQVKVNKY 1487
Cdd:pfam05483 321 IatkTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSL-EELLRTEQQRLEKNEDQLKIITMElQKKSSELEEMTKF 399
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1488 IGKQESVEERLSQLQSENMLLRQQLDDAHNKADN--------------KEKTVINIQDQFHAI----------VQKLQAE 1543
Cdd:pfam05483 400 KNNKEVELEELKKILAEDEKLLDEKKQFEKIAEElkgkeqelifllqaREKEIHDLEIQLTAIktseehylkeVEDLKTE 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1544 SEKQSLlleeRNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKK 1623
Cdd:pfam05483 480 LEKEKL----KNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVRE 555
|
....*...
gi 2462517863 1624 KLGQIRNQ 1631
Cdd:pfam05483 556 EFIQKGDE 563
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1168-1611 |
1.44e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.23 E-value: 1.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1168 DTLYEKIREqLRRKEEQYrkevevkQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDgiLTNHL-S 1246
Cdd:COG4717 74 KELEEELKE-AEEKEEEY-------AELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEA--LEAELaE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1247 KQKEIEMAQKKMnsenshshEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLkivKEKNEDLQKTIKQNE 1326
Cdd:COG4717 144 LPERLEELEERL--------EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL---AEELEELQQRLAELE 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1327 ETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESyhSRLAAAIHDRDQSETSKRELELAFQRA------- 1399
Cdd:COG4717 213 EELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAA--ALLALLGLGGSLLSLILTIAGVLFLVLgllallf 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1400 -RDECSRLQDKMNFDVSNLKDNNEILSQQlfKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQ 1478
Cdd:COG4717 291 lLLAREKASLGKEAEELQALPALEELEEE--ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEL 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1479 NEQVKVNKYIGKQESVEE---------RLSQLQSENMLLRQQLDDAHN--KADNKEKTVINIQDQFHAIVQKLQAESEKQ 1547
Cdd:COG4717 369 EQEIAALLAEAGVEDEEElraaleqaeEYQELKEELEELEEQLEELLGelEELLEALDEEELEEELEELEEELEELEEEL 448
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 1548 SLLLEERnKELISECNHLkERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYR 1611
Cdd:COG4717 449 EELREEL-AELEAELEQL-EEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYR 510
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
68-117 |
1.45e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 46.96 E-value: 1.45e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2462517863 68 LRKNG---LNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTAL 117
Cdd:pfam13857 1 LLEHGpidLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTAL 53
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1098-1601 |
1.57e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.14 E-value: 1.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1098 ERLLELKKNHCELLTVKIKKMEDKVNVLQR---ELSETKEIKSQLEHQKVEWERELCSLRFSLNQEE----EKRRNADTL 1170
Cdd:PRK03918 199 EKELEEVLREINEISSELPELREELEKLEKevkELEELKEEIEELEKELESLEGSKRKLEEKIRELEerieELKKEIEEL 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1171 YEKIRE--QLRRKEEQYR-------KEVEVKQQLELSLQTLEMELRTV----------KSNLNQVVQERNDAQRQLSR-E 1230
Cdd:PRK03918 279 EEKVKElkELKEKAEEYIklsefyeEYLDELREIEKRLSRLEEEINGIeerikeleekEERLEELKKKLKELEKRLEElE 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1231 QNARMLQDGiltnhLSKQKEIEMAQKKMNSENSHSHEEE-KDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKeKKCFEDLK 1309
Cdd:PRK03918 359 ERHELYEEA-----KAKKEELERLKKRLTGLTPEKLEKElEELEKAKEEIEEEISKITARIGELKKEIKEL-KKAIEELK 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1310 IVKEKNEDLQKTIkqNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESyHSRLAAAIHDRDQ----- 1384
Cdd:PRK03918 433 KAKGKCPVCGREL--TEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKLKELAEQlkele 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1385 SETSKRELELAFQRARD--ECSRLQDKMNFDVSNLKDN---NEILSQQLFKTESKLNSLEIEFHHTRDALREktLGLERV 1459
Cdd:PRK03918 510 EKLKKYNLEELEKKAEEyeKLKEKLIKLKGEIKSLKKElekLEELKKKLAELEKKLDELEEELAELLKELEE--LGFESV 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1460 QKDLSqtqcQMKEMEQKYqneqvkvNKYIgKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQK 1539
Cdd:PRK03918 588 EELEE----RLKELEPFY-------NEYL-ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462517863 1540 LQAESEKQsllLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSE 1601
Cdd:PRK03918 656 YSEEEYEE---LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1089-1634 |
2.33e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 52.42 E-value: 2.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1089 KIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEhQKVEWERElcslrfSLNQEEEKRRNAD 1168
Cdd:pfam05483 223 KIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLE-EKTKLQDE------NLKELIEKKDHLT 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1169 TLYEKIREQLRRK-------EEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQ---RQLSREQNARML-- 1236
Cdd:pfam05483 296 KELEDIKMSLQRSmstqkalEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTcslEELLRTEQQRLEkn 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1237 --QDGILTNHLSKQ-KEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEeiamlRLEIDTIKNQNQEKEKKCFEDLKIVKE 1313
Cdd:pfam05483 376 edQLKIITMELQKKsSELEEMTKFKNNKEVELEELKKILAEDEKLLDE-----KKQFEKIAEELKGKEQELIFLLQAREK 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1314 KNEDLQKTIkqneeTLTQTISQYngrlsvLTAENAMLNSKLENEKQSKERLEAevesyHSRLAAAIHDRDQSETSKRELE 1393
Cdd:pfam05483 451 EIHDLEIQL-----TAIKTSEEH------YLKEVEDLKTELEKEKLKNIELTA-----HCDKLLLENKELTQEASDMTLE 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1394 LAFQRAR-DECSRLQDKMNFDVSNLKDNNEILSQQlfkteskLNSLEIEFHHTRDALREKtlgLERVQKDLSQTQCQMKE 1472
Cdd:pfam05483 515 LKKHQEDiINCKKQEERMLKQIENLEEKEMNLRDE-------LESVREEFIQKGDEVKCK---LDKSEENARSIEYEVLK 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1473 MEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLR-------QQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAE-- 1543
Cdd:pfam05483 585 KEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKkkgsaenKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEie 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1544 ----SEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL-----EVTSRYRINL 1614
Cdd:pfam05483 665 dkkiSEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLyknkeQEQSSAKAAL 744
|
570 580
....*....|....*....|
gi 2462517863 1615 EDETQDLKKKLGQIRNQPEL 1634
Cdd:pfam05483 745 EIELSNIKAELLSLKKQLEI 764
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
50-100 |
2.49e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 46.11 E-value: 2.49e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 2462517863 50 IHKAASAGNVAKVQqilLLRKNG--LNDRDKMNRTALHLACANGHPEVVTLLV 100
Cdd:pfam13637 5 LHAAAASGHLELLR---LLLEKGadINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1375-1631 |
2.76e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.69 E-value: 2.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1375 LAAAIHDRDQSETSKRELELAFQRARDECSRLQDKmnfdVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTL 1454
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKE----EKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1455 GLERVQKDLSQTQCQMKEMEQKYQNeqvkvnkyIGKQESVEERLSQLQSENMLLRQQLDDAHNKADnkektviniQDQFH 1534
Cdd:COG4942 91 EIAELRAELEAQKEELAELLRALYR--------LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPAR---------REQAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1535 AIVQKLQAESEKQSLLLEERnKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSmseaslevtsryriNL 1614
Cdd:COG4942 154 ELRADLAELAALRAELEAER-AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA--------------EL 218
|
250
....*....|....*..
gi 2462517863 1615 EDETQDLKKKLGQIRNQ 1631
Cdd:COG4942 219 QQEAEELEALIARLEAE 235
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1162-1596 |
3.15e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.99 E-value: 3.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1162 EKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSR-EQNARMLQdgi 1240
Cdd:PRK03918 158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKlEKEVKELE--- 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1241 ltnhlSKQKEIEMAQKKMNSENSHSHEEEKDLSHknsmLQEEIAMLRLEIDTIKNQNQE-----KEKKCFEDLKIVKEKN 1315
Cdd:PRK03918 235 -----ELKEEIEELEKELESLEGSKRKLEEKIRE----LEERIEELKKEIEELEEKVKElkelkEKAEEYIKLSEFYEEY 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1316 EDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLE----------------AEVESYHSRLAA-- 1377
Cdd:PRK03918 306 LDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEeleerhelyeeakakkEELERLKKRLTGlt 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1378 ---AIHDRDQSETSKRELELAFQRARDECSRLQDKmnfdVSNLKDNNEILSQQlfKTESKLNSLEIEFHHTRDALREKTL 1454
Cdd:PRK03918 386 pekLEKELEELEKAKEEIEEEISKITARIGELKKE----IKELKKAIEELKKA--KGKCPVCGRELTEEHRKELLEEYTA 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1455 GLERVQKDLSQTqcqmKEMEQKYQNEQVKVNKYIGKqesvEERLSQLQSenmlLRQQLDDAHNKADnkektVINIqdqfh 1534
Cdd:PRK03918 460 ELKRIEKELKEI----EEKERKLRKELRELEKVLKK----ESELIKLKE----LAEQLKELEEKLK-----KYNL----- 517
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462517863 1535 aivQKLQAESEKQSLLLEERNKeLISECNHLK---ERQYQYENEKAEREVVVRQLQQELADTLKK 1596
Cdd:PRK03918 518 ---EELEKKAEEYEKLKEKLIK-LKGEIKSLKkelEKLEELKKKLAELEKKLDELEEELAELLKE 578
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
56-237 |
3.45e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 51.50 E-value: 3.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 56 AGNVAKVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQ------------- 122
Cdd:PHA02874 11 SGDIEAIEKIIKNKGNCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKigahdiikllidn 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 123 ----------CQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQ 192
Cdd:PHA02874 91 gvdtsilpipCIEKDMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFF 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2462517863 193 QMVEFLIKKKANVNAVD-KLESSHQLISEYKEERIPKHSSQNSNSV 237
Cdd:PHA02874 171 DIIKLLLEKGAYANVKDnNGESPLHNAAEYGDYACIKLLIDHGNHI 216
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1098-1579 |
3.99e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.99 E-value: 3.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1098 ERLLELKKNHCELltVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQ 1177
Cdd:PRK03918 273 KEIEELEEKVKEL--KELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKEL 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1178 LRRKEEqyrkevevkqqLELSLQTLEmELRTVKSNLNQVVQERNDaqrqLSREQNARMLQDgiltnhLSKQK-EIEMAQK 1256
Cdd:PRK03918 351 EKRLEE-----------LEERHELYE-EAKAKKEELERLKKRLTG----LTPEKLEKELEE------LEKAKeEIEEEIS 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1257 KMNSENSHSHEEEKDLSHKNSMLQ-------------------EEIAMLRLEIDTIKNQNQEKEKKcFEDLKIVKEKNED 1317
Cdd:PRK03918 409 KITARIGELKKEIKELKKAIEELKkakgkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEK-ERKLRKELRELEK 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1318 L---QKTIKQNEETLTQtISQYNGRLSVLTAENamLNSKLENEKQSKERLeAEVESYHSRLAAAIHDRDQSETSKRELEL 1394
Cdd:PRK03918 488 VlkkESELIKLKELAEQ-LKELEEKLKKYNLEE--LEKKAEEYEKLKEKL-IKLKGEIKSLKKELEKLEELKKKLAELEK 563
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1395 AFQRARDECSRLQDKM-NFDVSNLKDNNEILSQ---------QLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLS 1464
Cdd:PRK03918 564 KLDELEEELAELLKELeELGFESVEELEERLKElepfyneylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLE 643
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1465 QTQCQMKEMEQKYQNEqvkvnkyigKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIvqklqaES 1544
Cdd:PRK03918 644 ELRKELEELEKKYSEE---------EYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER------EK 708
|
490 500 510
....*....|....*....|....*....|....*
gi 2462517863 1545 EKQSLLLEERNKELISEcnhLKERQYQYENEKAER 1579
Cdd:PRK03918 709 AKKELEKLEKALERVEE---LREKVKKYKALLKER 740
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1108-1630 |
5.54e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 51.26 E-value: 5.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1108 CELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFslnQEEEKRRNADTLYEKIREQLRRKEEQYRK 1187
Cdd:pfam05483 157 CNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRV---QAENARLEMHFKLKEDHEKIQHLEEEYKK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1188 EVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNarmLQDGILTNHLSKQKEIEMAQKKMNSENSHSHE 1267
Cdd:pfam05483 234 EINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTK---LQDENLKELIEKKDHLTKELEDIKMSLQRSMS 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1268 EEKDLSHKNSMLQEEIAMLRLEidtiKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAEN 1347
Cdd:pfam05483 311 TQKALEEDLQIATKTICQLTEE----KEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMEL 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1348 AMLNSKLENEKQSKERLEAEVESYHSRLA---AAIHDRDQSET-------SKRELELAFQRARDECSRLQdkmnFDVSNL 1417
Cdd:pfam05483 387 QKKSSELEEMTKFKNNKEVELEELKKILAedeKLLDEKKQFEKiaeelkgKEQELIFLLQAREKEIHDLE----IQLTAI 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1418 KDNNEILSQQL--FKTE---SKLNSLEIEFHHTRDALREKTLglervQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQE 1492
Cdd:pfam05483 463 KTSEEHYLKEVedLKTElekEKLKNIELTAHCDKLLLENKEL-----TQEASDMTLELKKHQEDIINCKKQEERMLKQIE 537
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1493 SVEERLSQLQSENMLLR----QQLDDAHNKADNKEKTVINIqdqfhaivqklqaesEKQSLLLEERNKELISECNHLKEr 1568
Cdd:pfam05483 538 NLEEKEMNLRDELESVReefiQKGDEVKCKLDKSEENARSI---------------EYEVLKKEKQMKILENKCNNLKK- 601
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462517863 1569 qyQYENEKAErevvVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRN 1630
Cdd:pfam05483 602 --QIENKNKN----IEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIID 657
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1432-1631 |
5.75e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.48 E-value: 5.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1432 ESKLNSLEIEfhhTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQ 1511
Cdd:COG1196 199 ERQLEPLERQ---AEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1512 LDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSlLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELA 1591
Cdd:COG1196 276 LEELELELEEAQAEEYELLAELARLEQDIARLEERRR-ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2462517863 1592 DTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQ 1631
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1072-1553 |
5.78e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 5.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1072 LLIEQLGmecKDSVSLLKIQDaalsceRLLELKKNHCELLTVKIKKMEDKvnvlQRELSETKEIKSQLEHQKVEWERELC 1151
Cdd:COG4717 46 MLLERLE---KEADELFKPQG------RKPELNLKELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1152 SLRFSLNQEEEKRRNADTL--YEKIREQLRRKEEQYRkevEVKQQLElSLQTLEMELRTVKSNLNQVVQERNDAQRQLSR 1229
Cdd:COG4717 113 ELREELEKLEKLLQLLPLYqeLEALEAELAELPERLE---ELEERLE-ELRELEEELEELEAELAELQEELEELLEQLSL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1230 EQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEE------------IAMLRLEIDTIKNQN 1297
Cdd:COG4717 189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALeerlkearllllIAAALLALLGLGGSL 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1298 QEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAA 1377
Cdd:COG4717 269 LSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1378 AIHDRDQSETSKRELELafQRARDECSRLQDKmnFDVSNLKDNNEILSQ--QLFKTESKLNSLEIEFHHTRDALRE--KT 1453
Cdd:COG4717 349 LQELLREAEELEEELQL--EELEQEIAALLAE--AGVEDEEELRAALEQaeEYQELKEELEELEEQLEELLGELEEllEA 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1454 LGLERVQKDLSQTQCQMKEMEQKYQNEQvkvnkyiGKQESVEERLSQLQSENML--LRQQLDDAHNKADNKEKTVINIQD 1531
Cdd:COG4717 425 LDEEELEEELEELEEELEELEEELEELR-------EELAELEAELEQLEEDGELaeLLQELEELKAELRELAEEWAALKL 497
|
490 500
....*....|....*....|...
gi 2462517863 1532 QFHAIVQKLQ-AESEKQSLLLEE 1553
Cdd:COG4717 498 ALELLEEAREeYREERLPPVLER 520
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
82-202 |
6.11e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 51.17 E-value: 6.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 82 TALHLACANGHPEVVTLLVDRKCQLN------VCDNENRTALMK--------AVQCQEEKCATILLEHGADPNLADVHGN 147
Cdd:cd22192 91 TALHIAVVNQNLNLVRELIARGADVVspratgTFFRPGPKNLIYygehplsfAACVGNEEIVRLLIEHGADIRAQDSLGN 170
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462517863 148 TALHYAVYNEDISVATK----LLLYDANIEA------KNKDDLTPLLLAVSGKKQQMVEFLIKKK 202
Cdd:cd22192 171 TVLHILVLQPNKTFACQmydlILSYDKEDDLqpldlvPNNQGLTPFKLAAKEGNIVMFQHLVQKR 235
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1110-1646 |
7.84e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.99 E-value: 7.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1110 LLTVKIKKMEDKVNVLQRELSET-KEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKE----EQ 1184
Cdd:pfam12128 262 HLHFGYKSDETLIASRQEERQETsAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLdadiET 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1185 YRKEVEVKQQLELSLQTLEMELRTVKSNLNQVvQERNDAQRQLSREQNARMLQDgiLTNHLSKQKEIEMAQKKmnsensh 1264
Cdd:pfam12128 342 AAADQEQLPSWQSELENLEERLKALTGKHQDV-TAKYNRRRSKIKEQNNRDIAG--IKDKLAKIREARDRQLA------- 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1265 shEEEKDLSHKNSMLQEEIAMLRLEIdtikNQNQEKEKKCFEDLKIvkeknedLQKTIKQNEETLTQTisqyngrlsvlt 1344
Cdd:pfam12128 412 --VAEDDLQALESELREQLEAGKLEF----NEEEYRLKSRLGELKL-------RLNQATATPELLLQL------------ 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1345 aenAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDK-----------MNFD 1413
Cdd:pfam12128 467 ---ENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtllhfLRKE 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1414 VSNLKDN--NEILSQQLFKT-------------ESKLNSLEI--------EFHHTRDALREKtlgLERVQKDLSQTQCQM 1470
Cdd:pfam12128 544 APDWEQSigKVISPELLHRTdldpevwdgsvggELNLYGVKLdlkridvpEWAASEEELRER---LDKAEEALQSAREKQ 620
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1471 KEMEQkyqnEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAH-NKADNKEKTVINIQDQFHAIVQKLQAESE---- 1545
Cdd:pfam12128 621 AAAEE----QLVQANGELEKASREETFARTALKNARLDLRRLFDEKqSEKDKKNKALAERKDSANERLNSLEAQLKqldk 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1546 KQSLLLEERNKELISecnHLKERQYQYENEKAEREVVVRQLQQELA----------DTLKKQSMSE-ASLEVTSRYRINL 1614
Cdd:pfam12128 697 KHQAWLEEQKEQKRE---ARTEKQAYWQVVEGALDAQLALLKAAIAarrsgakaelKALETWYKRDlASLGVDPDVIAKL 773
|
570 580 590
....*....|....*....|....*....|....*.
gi 2462517863 1615 EDETQDLKKKLGQI-RNQPELGSVDSY---RFPTQR 1646
Cdd:pfam12128 774 KREIRTLERKIERIaVRRQEVLRYFDWyqeTWLQRR 809
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1116-1540 |
7.92e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.84 E-value: 7.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1116 KKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNAdtlyEKIREQLRRKEEQYRKEVEvkqQL 1195
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEI----EKEIEQLEQEEEKLKERLE---EL 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1196 ELSLQTLEmelrtvksnlnqvvQERNDAQRQLsrEQNARMLQDgiltnhlsKQKEIEMAQKKMNS-ENSHSHEEEKDLSH 1274
Cdd:TIGR02169 743 EEDLSSLE--------------QEIENVKSEL--KELEARIEE--------LEEDLHKLEEALNDlEARLSHSRIPEIQA 798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1275 KNSMLQEEIAMLRLEIDTI-KNQNQEKEKKCFEDLKI--VKEKNEDLQKTIKQNEETLtqtisqyngrlsvltaenAMLN 1351
Cdd:TIGR02169 799 ELSKLEEEVSRIEARLREIeQKLNRLTLEKEYLEKEIqeLQEQRIDLKEQIKSIEKEI------------------ENLN 860
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1352 SKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELelafQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKT 1431
Cdd:TIGR02169 861 GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLREL----ERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1432 ESKLNSLEIEfhhtrdalREKTLGLERVQKDLSQTQCQMKEMEQkyqneqvkVN-KYIGKQESVEERLSQLQSENMLL-- 1508
Cdd:TIGR02169 937 EDPKGEDEEI--------PEEELSLEDVQAELQRVEEEIRALEP--------VNmLAIQEYEEVLKRLDELKEKRAKLee 1000
|
410 420 430
....*....|....*....|....*....|....*...
gi 2462517863 1509 -RQQLDDAHNKADNKEKTV-----INIQDQFHAIVQKL 1540
Cdd:TIGR02169 1001 eRKAILERIEEYEKKKREVfmeafEAINENFNEIFAEL 1038
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
82-202 |
8.77e-06 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 50.46 E-value: 8.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 82 TALHLACANGHPEVVTLLVDRKCQLNV---CD-------------NENRTALMKAVQcqEEKCATILLEHGADPNLADVH 145
Cdd:TIGR00870 130 TALHLAAHRQNYEIVKLLLERGASVPAracGDffvksqgvdsfyhGESPLNAAACLG--SPSIVALLSEDPADILTADSL 207
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462517863 146 GNTALHYAVYNEDISVATK---------LLLYDANI-------EAKNKDDLTPLLLAVSGKKQQMVEFLIKKK 202
Cdd:TIGR00870 208 GNTLLHLLVMENEFKAEYEelscqmynfALSLLDKLrdskeleVILNHQGLTPLKLAAKEGRIVLFRLKLAIK 280
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
41-209 |
1.06e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 49.96 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 41 HVRDRDLGK-IHKAASAGNVAKVQQILLLRKNgLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMK 119
Cdd:PHA02874 118 NIKDAELKTfLHYAIKKGDLESIKMLFEYGAD-VNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHN 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 120 AVQCQEEKCATILLEHGADPNLADVHGNTALHYAV-YNEDisvATKLLLYDANIEAKNKDDLTPLLLAVSGK-KQQMVEF 197
Cdd:PHA02874 197 AAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIiHNRS---AIELLINNASINDQDIDGSTPLHHAINPPcDIDIIDI 273
|
170
....*....|..
gi 2462517863 198 LIKKKANVNAVD 209
Cdd:PHA02874 274 LLYHKADISIKD 285
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1089-1370 |
1.12e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.44 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1089 KIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNAD 1168
Cdd:TIGR02168 716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK 795
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1169 TLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSR--------EQNARMLQDGI 1240
Cdd:TIGR02168 796 EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlaaeieelEELIEELESEL 875
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1241 ltNHLSKQK------------EIEMAQKKMNSENSHSHEEEKDLSHKNSML---QEEIAMLRLEIDTIKNQNQEKEKKCF 1305
Cdd:TIGR02168 876 --EALLNERasleealallrsELEELSEELRELESKRSELRRELEELREKLaqlELRLEGLEVRIDNLQERLSEEYSLTL 953
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462517863 1306 EDLKIVKEKNEDLQKTIKQNEETLTQTI--------------SQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1370
Cdd:TIGR02168 954 EEAEALENKIEDDEEEARRRLKRLENKIkelgpvnlaaieeyEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARE 1032
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1161-1515 |
1.60e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.97 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1161 EEKRRNADTLYEKIREQLRRKEeqyrkevevkqqlelslqtLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGI 1240
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAE-------------------LIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYL 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1241 LTNHLSK--QKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQnQEKEKKCFEDLKIVKEKNEDL 1318
Cdd:pfam02463 227 LYLDYLKlnEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQ-EEELKLLAKEEEELKSELLKL 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1319 QKTIKQNEEtltqtisqyngRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQR 1398
Cdd:pfam02463 306 ERRKVDDEE-----------KLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEE 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1399 ARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQK--DLSQTQCQMKEMEQK 1476
Cdd:pfam02463 375 LLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEEsiELKQGKLTEEKEELE 454
|
330 340 350
....*....|....*....|....*....|....*....
gi 2462517863 1477 YQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDA 1515
Cdd:pfam02463 455 KQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQ 493
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
146-199 |
1.61e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.80 E-value: 1.61e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 146 GNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLI 199
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
51-179 |
1.80e-05 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 49.51 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 51 HKAASAGNVAKvqQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLlvdrkcqlnvcdnenrtalmkavqcqeekcat 130
Cdd:PTZ00322 88 QLAASGDAVGA--RILLTGGADPNCRDYDGRTPLHIACANGHVQVVRV-------------------------------- 133
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2462517863 131 iLLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLY---DANIEAKNKDD 179
Cdd:PTZ00322 134 -LLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHsqcHFELGANAKPD 184
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1311-1515 |
2.81e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 49.14 E-value: 2.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1311 VKEKNEDLQKTIKQneetLTQTISQYNGRLSVLTAEN-------------AMLNSKLENEKQSKERLEAEVESYHSRLAA 1377
Cdd:PRK11281 78 QKEETEQLKQQLAQ----APAKLRQAQAELEALKDDNdeetretlstlslRQLESRLAQTLDQLQNAQNDLAEYNSQLVS 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1378 AihdRDQSETSKRELELAFQRArdecsrlqDKMNFDVSNLKDNNEILS---QQLFKTESKLNSLEIEFHHT--------- 1445
Cdd:PRK11281 154 L---QTQPERAQAALYANSQRL--------QQIRNLLKGGKVGGKALRpsqRVLLQAEQALLNAQNDLQRKslegntqlq 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1446 ------RDALREKTLGLERV---------QKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQ---------- 1500
Cdd:PRK11281 223 dllqkqRDYLTARIQRLEHQlqllqeainSKRLTLSEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQrllkatekln 302
|
250
....*....|....*.
gi 2462517863 1501 -LQSENMLLRQQLDDA 1515
Cdd:PRK11281 303 tLTQQNLRVKNWLDRL 318
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1289-1599 |
3.33e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.86 E-value: 3.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1289 EIDTIKNQ--NQEKEKKCFEDLKIVKEKN----EDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKE 1362
Cdd:TIGR04523 41 KLKTIKNElkNKEKELKNLDKNLNKDEEKinnsNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1363 RLEAEVESYHSRLAA--AIHDRDQSETSKRELELafqrarDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEI 1440
Cdd:TIGR04523 121 KLEVELNKLEKQKKEnkKNIDKFLTEIKKKEKEL------EKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKN 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1441 EF---HHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHN 1517
Cdd:TIGR04523 195 KLlklELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1518 KADNKEKTVINIQDQFHAIVQKLQA-ESEKQslllEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADtLKK 1596
Cdd:TIGR04523 275 ELEQNNKKIKELEKQLNQLKSEISDlNNQKE----QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ-LKK 349
|
...
gi 2462517863 1597 QSM 1599
Cdd:TIGR04523 350 ELT 352
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1088-1590 |
5.38e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 48.18 E-value: 5.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1088 LKIQDAALSCERLLELKKNHcelltVKIKKMEDKvnvLQRELSETKEIKSQLEHQKVEWERELCSLRFSLnqeEEKRRNA 1167
Cdd:pfam05483 202 LRVQAENARLEMHFKLKEDH-----EKIQHLEEE---YKKEINDKEKQVSLLLIQITEKENKMKDLTFLL---EESRDKA 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1168 DTLYEKIR------EQLRRKEEQYRKEVE-VKQQLELSLQT---LEMELRTVKSNLNQVVQERNDAQRQLSREQNAR-ML 1236
Cdd:pfam05483 271 NQLEEKTKlqdenlKELIEKKDHLTKELEdIKMSLQRSMSTqkaLEEDLQIATKTICQLTEEKEAQMEELNKAKAAHsFV 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1237 QDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAML---RLEIDTIKNQNQEKEKKCFEdlkivKE 1313
Cdd:pfam05483 351 VTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKnnkEVELEELKKILAEDEKLLDE-----KK 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1314 KNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELe 1393
Cdd:pfam05483 426 QFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKEL- 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1394 laFQRARDECSRLQDKMNfDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRdalrektlglervqkdlsqtqcqmKEM 1473
Cdd:pfam05483 505 --TQEASDMTLELKKHQE-DIINCKKQEERMLKQIENLEEKEMNLRDELESVR------------------------EEF 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1474 EQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEE 1553
Cdd:pfam05483 558 IQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIK 637
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 2462517863 1554 RNK---ELISECNHLKERQYQYENEKAEREVVVRQLQQEL 1590
Cdd:pfam05483 638 VNKlelELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEV 677
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1114-1473 |
6.27e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 6.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1114 KIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTlyekiREQLRRKEEQYRkevevkq 1193
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASA-----EREIAELEAELE------- 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1194 QLELS---LQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARmlqdgiltnhlsKQKEIEMAQKKMNSENSHSHEEEK 1270
Cdd:COG4913 679 RLDASsddLAALEEQLEELEAELEELEEELDELKGEIGRLEKEL------------EQAEEELDELQDRLEAAEDLARLE 746
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1271 DLSHKNSMLQEEIAmlrleidtiknqnQEKEKKCFEDLkivKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAE---- 1346
Cdd:COG4913 747 LRALLEERFAAALG-------------DAVERELRENL---EERIDALRARLNRAEEELERAMRAFNREWPAETADldad 810
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1347 -------NAMLNsKLENekqskERLEAevesYHSRLAAAIHdrDQSETSKRELELAFQRARDECSRlqdkmnfdvsNLKD 1419
Cdd:COG4913 811 leslpeyLALLD-RLEE-----DGLPE----YEERFKELLN--ENSIEFVADLLSKLRRAIREIKE----------RIDP 868
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462517863 1420 NNEILSQQLFKTESKLnSLEI------EFHHTRDALREKTLGLERVQKDLSQTQC-QMKEM 1473
Cdd:COG4913 869 LNDSLKRIPFGPGRYL-RLEArprpdpEVREFRQELRAVTSGASLFDEELSEARFaALKRL 928
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1126-1630 |
6.97e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 47.71 E-value: 6.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1126 QRELSETKEIKSQLEHQkvewERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEME 1205
Cdd:TIGR04523 36 KQLEKKLKTIKNELKNK----EKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1206 LRTVKSNLNQVVQERNDAQRQLsreQNARMLQDGILTNHLSKQKEIEmaqkKMNSENSHSHEEEKDLSHKNSMLQEEIAM 1285
Cdd:TIGR04523 112 IKNDKEQKNKLEVELNKLEKQK---KENKKNIDKFLTEIKKKEKELE----KLNNKYNDLKKQKEELENELNLLEKEKLN 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1286 LRLEIDTIKNQNQEKEKKCFeDLKIVKEKNEDLQKTI---KQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKE 1362
Cdd:TIGR04523 185 IQKNIDKIKNKLLKLELLLS-NLKKKIQKNKSLESQIselKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1363 RLEaevesyhSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSnlKDNNEILSQQlfktESKLNSLEIEF 1442
Cdd:TIGR04523 264 KIK-------KQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQ----EKKLEEIQNQI 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1443 HHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNK 1522
Cdd:TIGR04523 331 SQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQK 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1523 EKTVINIQDQFHAI---VQKLQAESEKQSLL---LEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKK 1596
Cdd:TIGR04523 411 DEQIKKLQQEKELLekeIERLKETIIKNNSEikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKE 490
|
490 500 510
....*....|....*....|....*....|....
gi 2462517863 1597 QSMSEASLEVTSRYRINLEDETQDLKKKLGQIRN 1630
Cdd:TIGR04523 491 LKSKEKELKKLNEEKKELEEKVKDLTKKISSLKE 524
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
98-153 |
8.39e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 41.95 E-value: 8.39e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2462517863 98 LLVDRKCQLNVCDNENRTALMKAVQCqeeKCATI---LLEHGADPNLADVHGNTALHYA 153
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTPLHVAAKY---GALEIvrvLLAYGVDLNLKDEEGLTALDLA 56
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
889-1631 |
9.67e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 47.27 E-value: 9.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 889 MLKVEFQALEKEKVQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSgETDHQQFPRKENKEYASS 968
Cdd:pfam02463 202 LKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEK-EEEKLAQVLKENKEEEKE 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 969 GPALQMKEVKSTEKEKRTSKEsvnspvfgkasLLTGGLLQVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDD 1048
Cdd:pfam02463 281 KKLQEEELKLLAKEEEELKSE-----------LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEI 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1049 LTQSSETASEDCELphssyknfmLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKnhcELLTVKIKKMEDKVNVLQRE 1128
Cdd:pfam02463 350 KREAEEEEEEELEK---------LQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL---ELKSEEEKEAQLLLELARQL 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1129 LSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRT 1208
Cdd:pfam02463 418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1209 VKSNLnQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRL 1288
Cdd:pfam02463 498 RSQKE-SKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLG 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1289 EIDTIknqnQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTqtisqyngrlsvltaenAMLNSKLENEKQSKERLEAEV 1368
Cdd:pfam02463 577 ARKLR----LLIPKLKLPLKSIAVLEIDPILNLAQLDKATLE-----------------ADEDDKRAKVVEGILKDTELT 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1369 ESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKmnfdvsNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDA 1448
Cdd:pfam02463 636 KLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELL------EIQELQEKAESELAKEEILRRQLEIKKKEQREK 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1449 LREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNkyIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVIN 1528
Cdd:pfam02463 710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKID--EEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK 787
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1529 IQDQfhaivqklqAESEKQSLLLEER--NKELISECNHLKERQYQYENEKAEREVVVRQLQQELadtLKKQSMSEASLEV 1606
Cdd:pfam02463 788 VEEE---------KEEKLKAQEEELRalEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL---KEEQKLEKLAEEE 855
|
730 740
....*....|....*....|....*
gi 2462517863 1607 TSRYRINLEDETQDLKKKLGQIRNQ 1631
Cdd:pfam02463 856 LERLEEEITKEELLQELLLKEEELE 880
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1098-1631 |
1.37e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 46.96 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1098 ERLLELKKNHCElltvKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWEREL--CSLRFSLNQEEEKRRNADTLYEKIR 1175
Cdd:TIGR00606 301 EQLNDLYHNHQR----TVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQgrLQLQADRHQEHIRARDSLIQSLATR 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1176 EQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQ 1255
Cdd:TIGR00606 377 LELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEEL 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1256 KKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCF--EDLKIVKEKNEDLQKTIKQN--EETLTQ 1331
Cdd:TIGR00606 457 KFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLqnEKADLDRKLRKLDQEMEQLNhhTTTRTQ 536
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1332 TI-----------------SQYNGRLSVLTAE-------NAMLNSKLENEKQSKERLeAEVESYHSRLAAAIHDRDQSET 1387
Cdd:TIGR00606 537 MEmltkdkmdkdeqirkikSRHSDELTSLLGYfpnkkqlEDWLHSKSKEINQTRDRL-AKLNKELASLEQNKNHINNELE 615
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1388 SKRELELAFQRARDECSRLQDkMNFDVSNLKDNNEILSQQLFKTESKLNSleieFHHTRDALREKTLGLERVQKDLSQTQ 1467
Cdd:TIGR00606 616 SKEEQLSSYEDKLFDVCGSQD-EESDLERLKEEIEKSSKQRAMLAGATAV----YSQFITQLTDENQSCCPVCQRVFQTE 690
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1468 CQMKEMEQKYQNeqvKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAI---VQKLQAES 1544
Cdd:TIGR00606 691 AELQEFISDLQS---KLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVnrdIQRLKNDI 767
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1545 EKQSLLLEERNKELISECNHLKE----RQYQYENEKAEREV--------------VVRQLQQELADTLKKQSMSEASLEV 1606
Cdd:TIGR00606 768 EEQETLLGTIMPEEESAKVCLTDvtimERFQMELKDVERKIaqqaaklqgsdldrTVQQVNQEKQEKQHELDTVVSKIEL 847
|
570 580
....*....|....*....|....*
gi 2462517863 1607 TSRYRINLEDETQDLKKKLGQIRNQ 1631
Cdd:TIGR00606 848 NRKLIQDQQEQIQHLKSKTNELKSE 872
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
81-111 |
1.57e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 40.35 E-value: 1.57e-04
10 20 30
....*....|....*....|....*....|..
gi 2462517863 81 RTALHLACA-NGHPEVVTLLVDRKCQLNVCDN 111
Cdd:pfam00023 3 NTPLHLAAGrRGNLEIVKLLLSKGADVNARDK 34
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1038-1631 |
1.63e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.45 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1038 NQIQSMDDVDDLTqssetasedcELphssYKNFML-------LIEQLgmecKDSVSLLK-----IQDAALSCERLLELKK 1105
Cdd:COG4913 198 HKTQSFKPIGDLD----------DF----VREYMLeepdtfeAADAL----VEHFDDLEraheaLEDAREQIELLEPIRE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1106 NHcelltVKIKKMEDKVNVLQRELSETKEIKSQLEHQkvEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQY 1185
Cdd:COG4913 260 LA-----ERYAAARERLAELEYLRAALRLWFAQRRLE--LLEAELEELRAELARLEAELERLEARLDALREELDELEAQI 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1186 RK-EVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAqrQLSREQNARMLQDgiltnhlsKQKEIEMAQKKMNSENSH 1264
Cdd:COG4913 333 RGnGGDRLEQLEREIERLERELEERERRRARLEALLAAL--GLPLPASAEEFAA--------LRAEAAALLEALEEELEA 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1265 SHEEEKDLSHKNSMLQEEIAMLRLEIDTIKN------QNQEK-----EKKC---FEDLKI------VKEKNEDLQKTI-- 1322
Cdd:COG4913 403 LEEALAEAEAALRDLRRELRELEAEIASLERrksnipARLLAlrdalAEALgldEAELPFvgelieVRPEEERWRGAIer 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1323 ------------KQNEETLTQTISQYNGRLSVLTaenamlnSKLENEKQSKERLEAEVESYHSRLAAAIHD-RD--QSET 1387
Cdd:COG4913 483 vlggfaltllvpPEHYAAALRWVNRLHLRGRLVY-------ERVRTGLPDPERPRLDPDSLAGKLDFKPHPfRAwlEAEL 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1388 SKR------ELELAFQRAR----DECsrlQDKMNFDVSNLKDNNEILSQQL--FKTESKLNSLEIEfhhtRDALREKtlg 1455
Cdd:COG4913 556 GRRfdyvcvDSPEELRRHPraitRAG---QVKGNGTRHEKDDRRRIRSRYVlgFDNRAKLAALEAE----LAELEEE--- 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1456 LERVQKDLSQTQCQMKEMEQK---------YQNEQVKVnkyigkqESVEERLSQLQSEnmllRQQLDDAHNKadnkektV 1526
Cdd:COG4913 626 LAEAEERLEALEAELDALQERrealqrlaeYSWDEIDV-------ASAEREIAELEAE----LERLDASSDD-------L 687
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1527 INIQDQFHAIVQKLQaESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEaslEV 1606
Cdd:COG4913 688 AALEEQLEELEAELE-ELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD---AV 763
|
650 660
....*....|....*....|....*
gi 2462517863 1607 TSRYRINLEDETQDLKKKLGQIRNQ 1631
Cdd:COG4913 764 ERELRENLEERIDALRARLNRAEEE 788
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
81-202 |
1.83e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 46.03 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 81 RTALHLACANGHPEVVTLLVDRKC--QLNVCDNENRTA-----------LMKAVQCQEEKCATILLEHGADP---NLADV 144
Cdd:cd21882 74 QTALHIAIENRNLNLVRLLVENGAdvSARATGRFFRKSpgnlfyfgelpLSLAACTNQEEIVRLLLENGAQPaalEAQDS 153
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462517863 145 HGNTALHYAVYNED---------ISVATKLLLYDANI-------EAKNKDDLTPLLLAVSGKKQQMVEFLIKKK 202
Cdd:cd21882 154 LGNTVLHALVLQADntpensafvCQMYNLLLSYGAHLdptqqleEIPNHQGLTPLKLAAVEGKIVMFQHILQRE 227
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1080-1623 |
2.13e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 45.97 E-value: 2.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1080 ECKDSVSLLKIQDAALSCERLLELK-----KNHCELLTVKIKKMEDKvnvLQRELSETKEIKSQLE---HQKVEWERELC 1151
Cdd:pfam10174 251 DLEDEVQMLKTNGLLHTEDREEEIKqmevyKSHSKFMKNKIDQLKQE---LSKKESELLALQTKLEtltNQNSDCKQHIE 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1152 SLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNqvVQER--NDAQRQLSR 1229
Cdd:pfam10174 328 VLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLD--VKERkiNVLQKKIEN 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1230 EQNARMLQDGILTNHLSKQKEIEmaQKKMNSENSHSHEEEKdLSHKNSmlqeeiamlrleidTIKNQNQEKEKKCFEDLk 1309
Cdd:pfam10174 406 LQEQLRDKDKQLAGLKERVKSLQ--TDSSNTDTALTTLEEA-LSEKER--------------IIERLKEQREREDRERL- 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1310 ivkEKNEDLQKTIKQNEETLtqtisqyngrlsvltaenamlnSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSk 1389
Cdd:pfam10174 468 ---EELESLKKENKDLKEKV----------------------SALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKS- 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1390 reLELAFQRARDECSRLQdkmnfdvSNLKDNNEILSQQLFKTE--SKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQ 1467
Cdd:pfam10174 522 --LEIAVEQKKEECSKLE-------NQLKKAHNAEEAVRTNPEinDRIRLLEQEVARYKEESGKAQAEVERLLGILREVE 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1468 CQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLR-QQLDDAHNKADNKEKTVINIQdqfhaiVQKLQAESEK 1546
Cdd:pfam10174 593 NEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGaQLLEEARRREDNLADNSQQLQ------LEELMGALEK 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1547 QSLLLEERNKELISECNHLKERQYQYENEKAER----EVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLK 1622
Cdd:pfam10174 667 TRQELDATKARLSSTQQSLAEKDGHLTNLRAERrkqlEEILEMKQEALLAAISEKDANIALLELSSSKKKKTQEEVMALK 746
|
.
gi 2462517863 1623 K 1623
Cdd:pfam10174 747 R 747
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
1120-1346 |
2.73e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 45.82 E-value: 2.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1120 DKVNVLQRELSETKEIKSQLE----HQKV--EWERELCSLRFSLNQEEEKRRNadtlyekIREQLRRKE-EQyrKEVEVK 1192
Cdd:PRK10929 45 EIVEALQSALNWLEERKGSLErakqYQQVidNFPKLSAELRQQLNNERDEPRS-------VPPNMSTDAlEQ--EILQVS 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1193 QQL-ELS--LQTLEMELRTVKSNLNQVVQERNDAQRQLSreQNARMLQdgILTNHLSKQKEIEMAQKKMNSENSHSHEEE 1269
Cdd:PRK10929 116 SQLlEKSrqAQQEQDRAREISDSLSQLPQQQTEARRQLN--EIERRLQ--TLGTPNTPLAQAQLTALQAESAALKALVDE 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1270 KDLSHKNSMLQEEIAMLRLEI----------------DTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTI----KQNEEtL 1329
Cdd:PRK10929 192 LELAQLSANNRQELARLRSELakkrsqqldaylqalrNQLNSQRQREAERALESTELLAEQSGDLPKSIvaqfKINRE-L 270
|
250
....*....|....*..
gi 2462517863 1330 TQTISQYNGRLSVLTAE 1346
Cdd:PRK10929 271 SQALNQQAQRMDLIASQ 287
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
1264-1582 |
2.88e-04 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 45.06 E-value: 2.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1264 HSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKivkeKNEDLQKTIKQNEETltqtISQYNGRLSVL 1343
Cdd:pfam19220 45 QAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVA----RLAKLEAALREAEAA----KEELRIELRDK 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1344 TAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQ---DKMNFDVSNLKDN 1420
Cdd:pfam19220 117 TAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQalsEEQAAELAELTRR 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1421 NEILSQQLFKTESKLNSLEIEFHHTRdALREK----------TLGLER----------------VQKDLSQTQCQMKEME 1474
Cdd:pfam19220 197 LAELETQLDATRARLRALEGQLAAEQ-AERERaeaqleeaveAHRAERaslrmklealtaraaaTEQLLAEARNQLRDRD 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1475 QKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAH-------------NKA--------DNKEKTVINIQDQf 1533
Cdd:pfam19220 276 EAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQraraeleeraemlTKAlaakdaalERAEERIASLSDR- 354
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 2462517863 1534 haiVQKLQAESEKQSLLLEERNKELISEcnhlkerqyqYENEKAEREVV 1582
Cdd:pfam19220 355 ---IAELTKRFEVERAALEQANRRLKEE----------LQRERAERALA 390
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
1146-1631 |
3.00e-04 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 45.51 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1146 WERELCS-------------LRFS--LNQEEEkrrnadtLYEKIREQLRRKEEQYR--KEVEVKQQLELSLQTLEME--- 1205
Cdd:pfam07111 35 WEQDVSGdgqgpgrrgrsleLEGSqaLSQQAE-------LISRQLQELRRLEEEVRllRETSLQQKMRLEAQAMELDala 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1206 ------------LRT-------VKSNLNQVVQERNDAQRQLSREQNARMLQ--DGILTNHLSKQKEIEmaqKKMNSENSH 1264
Cdd:pfam07111 108 vaekagqaeaegLRAalagaemVRKNLEEGSQRELEEIQRLHQEQLSSLTQahEEALSSLTSKAEGLE---KSLNSLETK 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1265 SHEEEKDLshknSMLQEEIAMLRLEIDTIKnQNQEKEKKCFEDLK-----------------IVKEKNEDLQKTIKQNEE 1327
Cdd:pfam07111 185 RAGEAKQL----AEAQKEAELLRKQLSKTQ-EELEAQVTLVESLRkyvgeqvppevhsqtweLERQELLDTMQHLQEDRA 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1328 TLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAE--------VESYHSRLAAAIHDRDQSETSKRElelAFQRA 1399
Cdd:pfam07111 260 DLQATVELLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEfpkkcrslLNRWREKVFALMVQLKAQDLEHRD---SVKQL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1400 RDECSRLQDKmnfdVSNLKDNNEILSQQLFKTESKL-------NSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKE 1472
Cdd:pfam07111 337 RGQVAELQEQ----VTSQSQEQAILQRALQDKAAEVevermsaKGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSS 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1473 MEQKYQNEQVKVNKYIGKQESVEERLS--------------------QLQSENM--------------LLRQQLDDAHNK 1518
Cdd:pfam07111 413 TQIWLETTMTRVEQAVARIPSLSNRLSyavrkvhtikglmarkvalaQLRQESCpppppappvdadlsLELEQLREERNR 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1519 ADNKektvinIQDQFHAIVQKL-----QAESEKQSLL-----LE---ERNKELISECNHLKERQYQYENEKAEREVVVRQ 1585
Cdd:pfam07111 493 LDAE------LQLSAHLIQQEVgrareQGEAERQQLSevaqqLEqelQRAQESLASVGQQLEVARQGQQESTEEAASLRQ 566
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 2462517863 1586 ---LQQELADtlkkQSMSEASLEVTSRYRinleDETQDLKKKLGQIRNQ 1631
Cdd:pfam07111 567 eltQQQEIYG----QALQEKVAEVETRLR----EQLSDTKRRLNEARRE 607
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1280-1504 |
3.18e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.14 E-value: 3.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1280 QEEIAMLRLEIDTIKNQNQEKEKKcfedLKIVKEKNEDLQKTIKQneetLTQTISQYNGRLSVLTAENAMLNSKLENEKQ 1359
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKE----LAALKKEEKALLKQLAA----LERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1360 SKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLE 1439
Cdd:COG4942 91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462517863 1440 IEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSE 1504
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1114-1472 |
3.20e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 45.67 E-value: 3.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1114 KIKKMEDKVNVLQRELSETKEIKSQLEHQKveweRELCSLRFSLNQEEEKRRNADTLYEKIREQLrrkeeqyrkEVEVKQ 1193
Cdd:PRK11281 50 KQKLLEAEDKLVQQDLEQTLALLDKIDRQK----EETEQLKQQLAQAPAKLRQAQAELEALKDDN---------DEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1194 QLE-LSLQTLEmelrtvkSNLNQVVQERNDAQRQLSrEQNARMlqdgiltnhLSKQKEIEMAQKKMNSENSHSHEEEKDL 1272
Cdd:PRK11281 117 TLStLSLRQLE-------SRLAQTLDQLQNAQNDLA-EYNSQL---------VSLQTQPERAQAALYANSQRLQQIRNLL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1273 SH----KNSMLQEEIAMLRLEIDTIKNQNqekekkcfedlkivkekneDLQKTIKQNEETLTQTisqYNGRLSVLTAENA 1348
Cdd:PRK11281 180 KGgkvgGKALRPSQRVLLQAEQALLNAQN-------------------DLQRKSLEGNTQLQDL---LQKQRDYLTARIQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1349 mlnsklenekqskeRLEAEVESyhsrLAAAIHDR--DQSETSKRELElafqrARDECSRLQDkmNFDVSNLKDNNEILSQ 1426
Cdd:PRK11281 238 --------------RLEHQLQL----LQEAINSKrlTLSEKTVQEAQ-----SQDEAARIQA--NPLVAQELEINLQLSQ 292
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 2462517863 1427 QLFKTESKLNSLeiefhhTRDALREKTLgLERvqkdLSQTQCQMKE 1472
Cdd:PRK11281 293 RLLKATEKLNTL------TQQNLRVKNW-LDR----LTQSERNIKE 327
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1404-1633 |
3.28e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.89 E-value: 3.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1404 SRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVK 1483
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1484 VNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECN 1563
Cdd:COG4372 110 AEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELL 189
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1564 HLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQPE 1633
Cdd:COG4372 190 KEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKE 259
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1112-1628 |
3.71e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.42 E-value: 3.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1112 TVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEV 1191
Cdd:TIGR00606 397 TLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILEL 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1192 KQQLELSLQTL---------------EMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIemaqK 1256
Cdd:TIGR00606 477 DQELRKAERELskaeknsltetlkkeVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQI----R 552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1257 KMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIdtikNQNQEKekkcFEDLKIVKEKNEDLQKTIKQNEETLTQTISQY 1336
Cdd:TIGR00606 553 KIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEI----NQTRDR----LAKLNKELASLEQNKNHINNELESKEEQLSSY 624
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1337 NGRL----SVLTAENAMLNSKLENEKQSKER--LEAEVESYHSRLAAAIH---------DRD-QSETSKRELELAFQRAR 1400
Cdd:TIGR00606 625 EDKLfdvcGSQDEESDLERLKEEIEKSSKQRamLAGATAVYSQFITQLTDenqsccpvcQRVfQTEAELQEFISDLQSKL 704
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1401 DECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNE 1480
Cdd:TIGR00606 705 RLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESA 784
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1481 QV------KVNKYIGKQESVEERLSQLQSEN-----MLLRQQLDDAHNKADNKEKTVIniqdQFHAIVQKLQAESEKQSL 1549
Cdd:TIGR00606 785 KVcltdvtIMERFQMELKDVERKIAQQAAKLqgsdlDRTVQQVNQEKQEKQHELDTVV----SKIELNRKLIQDQQEQIQ 860
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1550 LLEERNKELISECNHLKE---RQYQYENEKAEREVVVRQLQQELAD---------TLKKQSMSEASLEVTSRYRIN--LE 1615
Cdd:TIGR00606 861 HLKSKTNELKSEKLQIGTnlqRRQQFEEQLVELSTEVQSLIREIKDakeqdspleTFLEKDQQEKEELISSKETSNkkAQ 940
|
570
....*....|...
gi 2462517863 1616 DETQDLKKKLGQI 1628
Cdd:TIGR00606 941 DKVNDIKEKVKNI 953
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1401-1568 |
4.33e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 45.07 E-value: 4.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1401 DE-CSRLqdKMNfdvsnlkdnNEILSQQLFKTESKLNSLEIEfhhtRDAL-REKTLG----LERVQKDLSQTQCQMKEME 1474
Cdd:COG0542 396 DEaAARV--RME---------IDSKPEELDELERRLEQLEIE----KEALkKEQDEAsferLAELRDELAELEEELEALK 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1475 QKYQNEQVKVNKYIGKQESVEERLSQLQSenmlLRQQLDDAHNKADNKEKTVINI--QDQFHAIV--------QKLQaES 1544
Cdd:COG0542 461 ARWEAEKELIEEIQELKEELEQRYGKIPE----LEKELAELEEELAELAPLLREEvtEEDIAEVVsrwtgipvGKLL-EG 535
|
170 180
....*....|....*....|....*
gi 2462517863 1545 EKQSLL-LEErnkelisecnHLKER 1568
Cdd:COG0542 536 EREKLLnLEE----------ELHER 550
|
|
| CEP63 |
pfam17045 |
Centrosomal protein of 63 kDa; CEP63 is a family of eukaryotic proteins involved in centriole ... |
1128-1408 |
4.76e-04 |
|
Centrosomal protein of 63 kDa; CEP63 is a family of eukaryotic proteins involved in centriole activity.
Pssm-ID: 465338 [Multi-domain] Cd Length: 264 Bit Score: 44.04 E-value: 4.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1128 ELSE-TKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNAdtlyekiREQLRRKEeqyrKEVEVKQQLELSLQTLEMEL 1206
Cdd:pfam17045 7 ELQElMKQIDIMVAHKKSEWEGQTRALETRLDIREEELLSA-------RNTLERKH----KEIGLLRQQLEELEKGKQEL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1207 rTVKSNlnqvvQERNDAQRQLSReqnarmlqdgiLTNHLSKqkeIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAML 1286
Cdd:pfam17045 76 -VAKYE-----QQLQKLQEELSK-----------LKRSYEK---LQRKQLKEAREEAKSREEDRSELSRLNGKLEEFRQK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1287 RLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQneetltqtiSQYNGRLSVLTA---ENAMLNSKLENEKQSKER 1363
Cdd:pfam17045 136 SLEWEQQRLQYQQQVASLEAQRKALAEQSSLIQSAAYQ---------VQLEGRKQCLEAsqsEIQRLRSKLERAQDSLCA 206
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 2462517863 1364 LEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQD 1408
Cdd:pfam17045 207 QELELERLRMRVSELGDSNRKLLEEQQRLLEELRMSQRQLQVLQN 251
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1254-1549 |
4.80e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 44.89 E-value: 4.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1254 AQKKMNSENSHSHEEEKDLShknsmLQEEIAMLRLEIDTIKNQNQEKeKKCFEDL-KIVKEKnEDLQKTIKQNEETLTQT 1332
Cdd:PLN02939 110 AIDNEQQTNSKDGEQLSDFQ-----LEDLVGMIQNAEKNILLLNQAR-LQALEDLeKILTEK-EALQGKINILEMRLSET 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1333 ISQyngrlSVLTAEnamlnsklenEKQSKERLEAEVESYHSRLAAAIHDRDQSETSkreLELAFQRARDECSRLQDKMNF 1412
Cdd:PLN02939 183 DAR-----IKLAAQ----------EKIHVEILEEQLEKLRNELLIRGATEGLCVHS---LSKELDVLKEENMLLKDDIQF 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1413 ---DVSNLKDNNE---ILSQQLFKTESKLNSLEIEFHHTR-----------DALREKTLGLERVQKDLSQTQCQMKEMEQ 1475
Cdd:PLN02939 245 lkaELIEVAETEErvfKLEKERSLLDASLRELESKFIVAQedvsklsplqyDCWWEKVENLQDLLDRATNQVEKAALVLD 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1476 KYQNEQVKVNKYigkQESVEE-RLSQLQSENMLLRQQ----LDDAHNKADNKEKTVINIQDQ----FHAIVQKLQAESEK 1546
Cdd:PLN02939 325 QNQDLRDKVDKL---EASLKEaNVSKFSSYKVELLQQklklLEERLQASDHEIHSYIQLYQEsikeFQDTLSKLKEESKK 401
|
...
gi 2462517863 1547 QSL 1549
Cdd:PLN02939 402 RSL 404
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1404-1612 |
5.54e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 5.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1404 SRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEI---EFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNE 1480
Cdd:COG4717 49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEkeeEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1481 QvkvnkYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEktviNIQDQFHAIVQKLQAESEKQSLLLEERNKELIS 1560
Cdd:COG4717 129 P-----LYQELEALEAELAELPERLEELEERLEELRELEEELE----ELEAELAELQEELEELLEQLSLATEEELQDLAE 199
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2462517863 1561 ECNHLKERQYQYENEKAEREVVVRQLQQELaDTLKKQSMSEASLEVTSRYRI 1612
Cdd:COG4717 200 ELEELQQRLAELEEELEEAQEELEELEEEL-EQLENELEAAALEERLKEARL 250
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
79-108 |
5.84e-04 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.72 E-value: 5.84e-04
10 20 30
....*....|....*....|....*....|
gi 2462517863 79 MNRTALHLACANGHPEVVTLLVDRKCQLNV 108
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1203-1544 |
6.01e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.83 E-value: 6.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1203 EMELRTVKSNLNQVVQER--NDAQRQLSREQNARMLQDgiltnhlskqkeIEMAQKKMNsenshsheeekdLSHKNSMLQ 1280
Cdd:pfam12128 192 EGKFRDVKSMIVAILEDDgvVPPKSRLNRQQVEHWIRD------------IQAIAGIMK------------IRPEFTKLQ 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1281 EEIAMLR---LEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLEN- 1356
Cdd:pfam12128 248 QEFNTLEsaeLRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAl 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1357 EKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARD---ECSRLQDKM----NFDVSNLKDN----NEILS 1425
Cdd:pfam12128 328 EDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDvtaKYNRRRSKIkeqnNRDIAGIKDKlakiREARD 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1426 QQLFKTESKLNSLEIEFHHTRDA----LREKTLG----LERVQKDLSQTQCQMKEMEQKYQNeQVKVNKYIGKQESVEER 1497
Cdd:pfam12128 408 RQLAVAEDDLQALESELREQLEAgkleFNEEEYRlksrLGELKLRLNQATATPELLLQLENF-DERIERAREEQEAANAE 486
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 2462517863 1498 LSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAES 1544
Cdd:pfam12128 487 VERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQA 533
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1171-1575 |
6.70e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.56 E-value: 6.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1171 YEKIREQLRRKEEQ---YRKEV-EVKQQLELSLQTL-EM--ELRTVKSNLNQVVQERNDAQRQLSREQNArmlqdgiltn 1243
Cdd:PRK04863 274 YMRHANERRVHLEEaleLRRELyTSRRQLAAEQYRLvEMarELAELNEAESDLEQDYQAASDHLNLVQTA---------- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1244 hLSKQKEIEMAQKkmnsenshsheeekDLSHKNSMLqEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIK 1323
Cdd:PRK04863 344 -LRQQEKIERYQA--------------DLEELEERL-EEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1324 qneetLTQT-ISQYNGRLSVLTAENAMLNS---KLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRA 1399
Cdd:PRK04863 408 -----VQQTrAIQYQQAVQALERAKQLCGLpdlTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLV 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1400 R---DECSRLQDKMNFdVSNLKDNNE--ILSQQLFKTESKLNSLEIEFHHTRDAlrektlglERVQKDLSQTQCQMKEME 1474
Cdd:PRK04863 483 RkiaGEVSRSEAWDVA-RELLRRLREqrHLAEQLQQLRMRLSELEQRLRQQQRA--------ERLLAEFCKRLGKNLDDE 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1475 QKYQNEQVKVNKyigKQESVEERLSQLQSENMLLRQQLDDAhnKADNKEKT------------VINIQDQFHAIVQKLQA 1542
Cdd:PRK04863 554 DELEQLQEELEA---RLESLSESVSEARERRMALRQQLEQL--QARIQRLAarapawlaaqdaLARLREQSGEEFEDSQD 628
|
410 420 430
....*....|....*....|....*....|....
gi 2462517863 1543 ESE-KQSLLLEERnkELISECNHLKERQYQYENE 1575
Cdd:PRK04863 629 VTEyMQQLLERER--ELTVERDELAARKQALDEE 660
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
80-108 |
7.40e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 38.39 E-value: 7.40e-04
10 20
....*....|....*....|....*....
gi 2462517863 80 NRTALHLACANGHPEVVTLLVDRKCQLNV 108
Cdd:pfam13606 2 GNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1277-1596 |
9.26e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 43.96 E-value: 9.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1277 SMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNE--ETLTQTISQYNGRLSVLTAENAMLNSKL 1354
Cdd:pfam05557 12 SQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEkrEAEAEEALREQAELNRLKKKYLEALNKK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1355 ENEKQSKErleAEVESYHSRLAAAIHDRdQSETSKRELELAFQRARDECSR----LQDKMNFDVSNLKDNNEILSQQLFK 1430
Cdd:pfam05557 92 LNEKESQL---ADAREVISCLKNELSEL-RRQIQRAELELQSTNSELEELQerldLLKAKASEAEQLRQNLEKQQSSLAE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1431 TESKLNSLEIEFH-HTRDALrektlglerVQKDLSQTQCQMKEMEqkyqneqvkvnKYIGKQESVEERLSQLQSENMLLR 1509
Cdd:pfam05557 168 AEQRIKELEFEIQsQEQDSE---------IVKNSKSELARIPELE-----------KELERLREHNKHLNENIENKLLLK 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1510 QQLDDAHNKADNKEKT---VINIQDQFHAIVQKLQA-ESEKQSLLLE--------ERNKELISECNHLKERQYQYENEKA 1577
Cdd:pfam05557 228 EEVEDLKRKLEREEKYreeAATLELEKEKLEQELQSwVKLAQDTGLNlrspedlsRRIEQLQQREIVLKEENSSLTSSAR 307
|
330
....*....|....*....
gi 2462517863 1578 EREVVVRQLQQELADTLKK 1596
Cdd:pfam05557 308 QLEKARRELEQELAQYLKK 326
|
|
| PHA02736 |
PHA02736 |
Viral ankyrin protein; Provisional |
75-203 |
9.79e-04 |
|
Viral ankyrin protein; Provisional
Pssm-ID: 165103 [Multi-domain] Cd Length: 154 Bit Score: 41.40 E-value: 9.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 75 DRDKMNRTALHLACANGhpEVVTLLVDRkcqlNVCDNENRTALMK----AVQC-----------QEEKCaTILLEHGADP 139
Cdd:PHA02736 12 EPDIEGENILHYLCRNG--GVTDLLAFK----NAISDENRYLVLEynrhGKQCvhivsnpdkadPQEKL-KLLMEWGADI 84
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462517863 140 NLAD-VHGNTALHYAVYNEDISVATKLLLY-DANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKA 203
Cdd:PHA02736 85 NGKErVFGNTPLHIAVYTQNYELATWLCNQpGVNMEILNYAFKTPYYVACERHDAKMMNILRAKGA 150
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1153-1364 |
1.04e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1153 LRFSLNQEEEKRRNADTLYEK----IREQLRRKE---EQYRKE-------------VEVKQQLELSLQTLEMELRTVKSN 1212
Cdd:COG3206 162 LEQNLELRREEARKALEFLEEqlpeLRKELEEAEaalEEFRQKnglvdlseeakllLQQLSELESQLAEARAELAEAEAR 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1213 LNQVvqernDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHeeekdlshknsmlqEEIAMLRLEIDT 1292
Cdd:COG3206 242 LAAL-----RAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNH--------------PDVIALRAQIAA 302
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462517863 1293 IKNQNQEKEKKCFEDLKIVKEknedlqkTIKQNEETLTQTISQYNGRLSVLTAENAMLNSkLENEKQSKERL 1364
Cdd:COG3206 303 LRAQLQQEAQRILASLEAELE-------ALQAREASLQAQLAQLEARLAELPELEAELRR-LEREVEVAREL 366
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
79-215 |
1.12e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 43.44 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 79 MNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNED 158
Cdd:PHA02875 1 MDQVALCDAILFGELDIARRLLDIGINPNFEIYDGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 159 ISVATKLLLYDANI-EAKNKDDLTPLLLAVSGKKQQMVEFLIKKKA--NVNAVDKLESSH 215
Cdd:PHA02875 81 VKAVEELLDLGKFAdDVFYKDGMTPLHLATILKKLDIMKLLIARGAdpDIPNTDKFSPLH 140
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1129-1619 |
1.13e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.88 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1129 LSETKEIKSQLEH-----QKVEWERELCSLRFSLNQEEEKRRNADTLYEK-------IREQLRRKEEQYRKEVEVKQQLE 1196
Cdd:TIGR00606 165 LSEGKALKQKFDEifsatRYIKALETLRQVRQTQGQKVQEHQMELKYLKQykekaceIRDQITSKEAQLESSREIVKSYE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1197 LSLQTLEMELRTVKSNLNQVVQERND----AQRQLSREQNARMLQ--------------DGILTNHLSKQKEIEMAQKKM 1258
Cdd:TIGR00606 245 NELDPLKNRLKEIEHNLSKIMKLDNEikalKSRKKQMEKDNSELElkmekvfqgtdeqlNDLYHNHQRTVREKERELVDC 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1259 NSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEK----------------EKKCFEDLKI------VKEKNE 1316
Cdd:TIGR00606 325 QRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARdsliqslatrleldgfERGPFSERQIknfhtlVIERQE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1317 DLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEkqsKERLEAEVEsyhsRLAAAIHDRDQSETSKR---ELE 1393
Cdd:TIGR00606 405 DEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELK---KEILEKKQE----ELKFVIKELQQLEGSSDrilELD 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1394 LAFQRARDECSRLQDKMNfdvsnlkdnneilSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEM 1473
Cdd:TIGR00606 478 QELRKAERELSKAEKNSL-------------TETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDK 544
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1474 EQKYQneQVKVNKYIGKQESVEerlsqlQSENMLLRQQLDDAHNKADNKektvINIQDQFHAIVQKLQAESEKQSLLLEE 1553
Cdd:TIGR00606 545 MDKDE--QIRKIKSRHSDELTS------LLGYFPNKKQLEDWLHSKSKE----INQTRDRLAKLNKELASLEQNKNHINN 612
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462517863 1554 RNKELISECNHLKERQYQYENEKAErEVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQ 1619
Cdd:TIGR00606 613 ELESKEEQLSSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQ 677
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
145-177 |
1.13e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 38.04 E-value: 1.13e-03
10 20 30
....*....|....*....|....*....|....
gi 2462517863 145 HGNTALHYAVYNE-DISVATKLLLYDANIEAKNK 177
Cdd:pfam00023 1 DGNTPLHLAAGRRgNLEIVKLLLSKGADVNARDK 34
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1424-1605 |
1.32e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.89 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1424 LSQQLFKTESKLNSLEIEFhhtrDALREKtlgLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKyigKQESVEERLSQLQS 1503
Cdd:COG3883 28 LQAELEAAQAELDALQAEL----EELNEE---YNELQAELEALQAEIDKLQAEIAEAEAEIEE---RREELGERARALYR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1504 E-------NMLLRQQ-LDDAHNKADNKEKtvinIQDQFHAIV---QKLQAESEKQSLLLEERNKELISECNHLKERQYQY 1572
Cdd:COG3883 98 SggsvsylDVLLGSEsFSDFLDRLSALSK----IADADADLLeelKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173
|
170 180 190
....*....|....*....|....*....|...
gi 2462517863 1573 ENEKAEREVVVRQLQQELADTLKKQSMSEASLE 1605
Cdd:COG3883 174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELA 206
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1139-1369 |
1.34e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.57 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1139 LEHQKVEWERelcslrfslnQEEEKrrnadtlYEKI-REQLRRKEEQYRKEVEVKQQLELSLQTLEMELR---TVKSNLN 1214
Cdd:pfam17380 278 VQHQKAVSER----------QQQEK-------FEKMeQERLRQEKEEKAREVERRRKLEEAEKARQAEMDrqaAIYAEQE 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1215 QVVQERN---DAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHShEEEKDLSHKNSMLQEE----IAMLR 1287
Cdd:pfam17380 341 RMAMERErelERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERV-RQELEAARKVKILEEErqrkIQQQK 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1288 LEIDTIKNQNQEKEKkcfEDLKIVKEKNEDLQKTIKQNEETLTQTISqyngRLSVLTAENAmlNSKLENEKQSKERLEAE 1367
Cdd:pfam17380 420 VEMEQIRAEQEEARQ---REVRRLEEERAREMERVRLEEQERQQQVE----RLRQQEEERK--RKKLELEKEKRDRKRAE 490
|
..
gi 2462517863 1368 VE 1369
Cdd:pfam17380 491 EQ 492
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
1112-1303 |
1.41e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 41.81 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1112 TVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCslRFSLNQEEE----KRRNADTlyEKIREQLRRKEEQYRk 1187
Cdd:pfam15619 10 LHKIKELQNELAELQSKLEELRKENRLLKRLQKRQEKALG--KYEGTESELpqliARHNEEV--RVLRERLRRLQEKER- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1188 evevkqQLELSLQTLEMELRTVKSNLNQVVQ--------ERNDAQRQLSREQNarMLQDgiltnhlsKQKEIEMAQKKM- 1258
Cdd:pfam15619 85 ------DLERKLKEKEAELLRLRDQLKRLEKlsedknlaEREELQKKLEQLEA--KLED--------KDEKIQDLERKLe 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2462517863 1259 NSENSHSHEEEKDLShKNSMLQEEIAMLRLEIDTIKNQNQEKEKK 1303
Cdd:pfam15619 149 LENKSFRRQLAAEKK-KHKEAQEEVKILQEEIERLQQKLKEKERE 192
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1245-1627 |
1.51e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 43.17 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1245 LSKQKEIEMAQKKMNSENSHSHEEEKD--------LSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNE 1316
Cdd:pfam05483 41 FQKLNFLPMLEQVANSGDCHYQEGLKDsdfensegLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1317 DLQKTIKQNEET---LTQTISQ-------------YNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIH 1380
Cdd:pfam05483 121 AIQELQFENEKVslkLEEEIQEnkdlikennatrhLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1381 D-RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERV 1459
Cdd:pfam05483 201 ElRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQ 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1460 QKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLsQLQSenmllrqqlddahnkadnkeKTVINIQDQFHAIVQK 1539
Cdd:pfam05483 281 DENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDL-QIAT--------------------KTICQLTEEKEAQMEE 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1540 LQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQEladtlkkqsmsEASLEVTSRYRINLEDETQ 1619
Cdd:pfam05483 340 LNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKK-----------SSELEEMTKFKNNKEVELE 408
|
....*...
gi 2462517863 1620 DLKKKLGQ 1627
Cdd:pfam05483 409 ELKKILAE 416
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
178-210 |
1.55e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 37.65 E-value: 1.55e-03
10 20 30
....*....|....*....|....*....|....
gi 2462517863 178 DDLTPLLLAV-SGKKQQMVEFLIKKKANVNAVDK 210
Cdd:pfam00023 1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARDK 34
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1423-1641 |
1.68e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.83 E-value: 1.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1423 ILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQ 1502
Cdd:COG4942 10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1503 SENMLLRQQLDDAHNK----------------------ADNKEKTVIN----------IQDQFHAIVQKLQAESEKQSLL 1550
Cdd:COG4942 90 KEIAELRAELEAQKEElaellralyrlgrqpplalllsPEDFLDAVRRlqylkylapaRREQAEELRADLAELAALRAEL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1551 LEERnKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTlkkqsmsEASLEVTSRYRINLEDETQDLKKKLGQIRN 1630
Cdd:COG4942 170 EAER-AELEALLAELEEERAALEALKAERQKLLARLEKELAEL-------AAELAELQQEAEELEALIARLEAEAAAAAE 241
|
250
....*....|.
gi 2462517863 1631 QPELGSVDSYR 1641
Cdd:COG4942 242 RTPAAGFAALK 252
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
1111-1331 |
1.77e-03 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 42.97 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1111 LTVKIKKMEDKVNVLQRE----LSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYR 1186
Cdd:pfam15964 408 LSQNVAQLEAQVEKVTREknslVSQLEEAQKQLASQEMDVTKVCGEMRYQLNQTKMKKDEAEKEHREYRTKTGRQLEIKD 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1187 KEVEvKQQLELSLQTLEME-------------------LRTVKSNLNQVVQERNDAQRQLSREQNARMLQdgiltnhlSK 1247
Cdd:pfam15964 488 QEIE-KLGLELSESKQRLEqaqqdaarareeclkltelLGESEHQLHLTRLEKESIQQSFSNEAKAQALQ--------AQ 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1248 QKEIEMAQKKMNSENSHS---HEEEKDLSHKNSM---LQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT 1321
Cdd:pfam15964 559 QREQELTQKMQQMEAQHDktvNEQYSLLTSQNTFiakLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKLQKR 638
|
250
....*....|
gi 2462517863 1322 IKQNEETLTQ 1331
Cdd:pfam15964 639 NEELEEQCVQ 648
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
1202-1525 |
1.82e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 43.12 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1202 LEMELRTVKSNLN----QVVQERNDA-----QRQLSREqNARMLQDGI-----LTNHLSKQKEIEMAQKKMNSENSHSHE 1267
Cdd:PRK10929 28 ITQELEQAKAAKTpaqaEIVEALQSAlnwleERKGSLE-RAKQYQQVIdnfpkLSAELRQQLNNERDEPRSVPPNMSTDA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1268 EEKDLSHKNSMLQEEIAMLrleidtikNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLtQTISQYN-----GRLSV 1342
Cdd:PRK10929 107 LEQEILQVSSQLLEKSRQA--------QQEQDRAREISDSLSQLPQQQTEARRQLNEIERRL-QTLGTPNtplaqAQLTA 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1343 LTAENAMLNSKLE---------NEKQSKERLEAEV-ESYHSRLAAAIHD-RDQ-SETSKRELELAFQRARDECSRLQDKM 1410
Cdd:PRK10929 178 LQAESAALKALVDelelaqlsaNNRQELARLRSELaKKRSQQLDAYLQAlRNQlNSQRQREAERALESTELLAEQSGDLP 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1411 NFDVSNLKDNNEI---LSQQ------LFKTESKLNSLEIEFHHTRDALREKT--LGLERVQKDLSQTQ-CQMKEMEqKYQ 1478
Cdd:PRK10929 258 KSIVAQFKINRELsqaLNQQaqrmdlIASQQRQAASQTLQVRQALNTLREQSqwLGVSNALGEALRAQvARLPEMP-KPQ 336
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 2462517863 1479 neQVKvnkyigkQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKT 1525
Cdd:PRK10929 337 --QLD-------TEMAQLRVQRLRYEDLLNKQPQLRQIRQADGQPLT 374
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
1116-1499 |
2.37e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 42.76 E-value: 2.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1116 KKMEDKVNVLQRELSETKeIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA---DTLYEKI---REQLRRKEEQYRKEV 1189
Cdd:COG5022 813 RSYLACIIKLQKTIKREK-KLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLlkkETIYLQSaqrVELAERQLQELKIDV 891
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1190 EVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQnARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEE 1269
Cdd:COG5022 892 KSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARL-KKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETS 970
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1270 KDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKcfedlkivKEKNEDLQKTIKQNEETltqtisqyNGRLSVLTAENAM 1349
Cdd:COG5022 971 EEYEDLLKKSTILVREGNKANSELKNFKKELAEL--------SKQYGALQESTKQLKEL--------PVEVAELQSASKI 1034
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1350 LNSKLENEKQSKErlEAEVESyhsrlaaaIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLF 1429
Cdd:COG5022 1035 ISSESTELSILKP--LQKLKG--------LLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVT 1104
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1430 KTESKLNSLEIEFHhtrDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVnKYIGKQESVEERLS 1499
Cdd:COG5022 1105 NRNLVKPANVLQFI---VAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLEL-DGLFWEANLEALPS 1170
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
50-224 |
2.53e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 42.17 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 50 IHKAASAGNVAKVQQiLLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNEnrTALMKAVQCQEEKCA 129
Cdd:PHA02878 41 LHQAVEARNLDVVKS-LLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMIRSINKCSVFYTL--VAIKDAFNNRNVEIF 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 130 TILLEHGADPN--LADVHGNTALHYAVYNEDIsvaTKLLL-YDANIEAKNKDDL-TPLLLAVSGKKQQMVEFLIKKKANV 205
Cdd:PHA02878 118 KIILTNRYKNIqtIDLVYIDKKSKDDIIEAEI---TKLLLsYGADINMKDRHKGnTALHYATENKDQRLTELLLSYGANV 194
|
170 180
....*....|....*....|.
gi 2462517863 206 NAVDKLESS--HQLISEYKEE 224
Cdd:PHA02878 195 NIPDKTNNSplHHAVKHYNKP 215
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
1027-1621 |
2.71e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 42.73 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1027 KKTSNEKNKVKNQIQSMDDVDDLTQSSETASEdcelphssyknfmllIEQlgmeckdsvsllKIQDAALSCErllelkkn 1106
Cdd:TIGR01612 1139 KKSENYIDEIKAQINDLEDVADKAISNDDPEE---------------IEK------------KIENIVTKID-------- 1183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1107 hcelltvKIKKMEDKVNVLQRELSETKEIKSQLEHQK---VEWERELCSLrFSLNQEEEKRRNADTL-----YEKIREQL 1178
Cdd:TIGR01612 1184 -------KKKNIYDEIKKLLNEIAEIEKDKTSLEEVKginLSYGKNLGKL-FLEKIDEEKKKSEHMIkameaYIEDLDEI 1255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1179 RRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSnlNQVVQERNDAQRQLSREQNARMLQDgiltnhLSKQKEIEMAQKKM 1258
Cdd:TIGR01612 1256 KEKSPEIENEMGIEMDIKAEMETFNISHDDDKD--HHIISKKHDENISDIREKSLKIIED------FSEESDINDIKKEL 1327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1259 NSENSHSHEEEKDLSHKNSMLQEEIAMLRL-EIDTIKNQNQEKEKKCFEDLKIVK---EKNEDLQKTIKQNE--ETLTQT 1332
Cdd:TIGR01612 1328 QKNLLDAQKHNSDINLYLNEIANIYNILKLnKIKKIIDEVKEYTKEIEENNKNIKdelDKSEKLIKKIKDDInlEECKSK 1407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1333 ISQyngrlsvlTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRA----RDECSRLQD 1408
Cdd:TIGR01612 1408 IES--------TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSqhilKIKKDNATN 1479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1409 KMNFDVSNLKDNNEilSQQLFKTESKLNSLEIEfhhtrdalREKTLgLERVQKDLSQTQCQMKEMEQKYQNEQVKV---- 1484
Cdd:TIGR01612 1480 DHDFNINELKEHID--KSKGCKDEADKNAKAIE--------KNKEL-FEQYKKDVTELLNKYSALAIKNKFAKTKKdsei 1548
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1485 ---------NKYIGKQESVEERLSQLQSENMllrqQLDDAHNKADNKEKTVINIQdqfhaivqkLQAESEKQSLLLEERN 1555
Cdd:TIGR01612 1549 iikeikdahKKFILEAEKSEQKIKEIKKEKF----RIEDDAAKNDKSNKAAIDIQ---------LSLENFENKFLKISDI 1615
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462517863 1556 KELISECnhLKERQyqyENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL 1621
Cdd:TIGR01612 1616 KKKINDC--LKETE---SIEKKISSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
145-174 |
2.90e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.80 E-value: 2.90e-03
10 20 30
....*....|....*....|....*....|
gi 2462517863 145 HGNTALHYAVYNEDISVATKLLLYDANIEA 174
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1116-1434 |
3.27e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.44 E-value: 3.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1116 KKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKR-----RNADTLYEKIREQLRRKEEQYRKEVE 1190
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKkaeeaKKAEEDEKKAAEALKKEAEEAKKAEE 1706
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1191 VKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARmlqdgiltnhlskqKEIEMAQKKMNSENSHSHEEEK 1270
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAK--------------KDEEEKKKIAHLKKEEEKKAEE 1772
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1271 DLSHKNSMLQEEiamLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQyngrlsVLTAENAML 1350
Cdd:PTZ00121 1773 IRKEKEAVIEEE---LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKE------VADSKNMQL 1843
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1351 NS--KLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDvsnlKDNNEILSQQL 1428
Cdd:PTZ00121 1844 EEadAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMA----GKNNDIIDDKL 1919
|
....*.
gi 2462517863 1429 FKTESK 1434
Cdd:PTZ00121 1920 DKDEYI 1925
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1098-1301 |
3.37e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.03 E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1098 ERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRfslnQEEEKRRNADTLYEKIREQ 1177
Cdd:pfam17380 410 ERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLR----QQEEERKRKKLELEKEKRD 485
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1178 LRRKEEQYRKEVEvkQQLELSLQTLEMELRTVKsnlnQVVQERNDAQRQLSREQNARMLQDgiltnhlSKQKEIEMAQKK 1257
Cdd:pfam17380 486 RKRAEEQRRKILE--KELEERKQAMIEEERKRK----LLEKEMEERQKAIYEEERRREAEE-------ERRKQQEMEERR 552
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2462517863 1258 MNSENSHSHEEEKDlshKNSMLQEEIAMLRleiDTIKNQNQEKE 1301
Cdd:pfam17380 553 RIQEQMRKATEERS---RLEAMEREREMMR---QIVESEKARAE 590
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1384-1627 |
3.55e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 42.04 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1384 QSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDL 1463
Cdd:pfam05557 13 QLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1464 SQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQfhaivQKLQAE 1543
Cdd:pfam05557 93 NEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQ-----QSSLAE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1544 SekqslllEERNKELISECNhlkerqyQYENEKAerevVVRQLQQELADTLKKQSMSEASLEVTSRYRIN------LEDE 1617
Cdd:pfam05557 168 A-------EQRIKELEFEIQ-------SQEQDSE----IVKNSKSELARIPELEKELERLREHNKHLNENienkllLKEE 229
|
250
....*....|
gi 2462517863 1618 TQDLKKKLGQ 1627
Cdd:pfam05557 230 VEDLKRKLER 239
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
1329-1439 |
3.70e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.49 E-value: 3.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1329 LTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELElafqRARDECSRLQD 1408
Cdd:PRK09039 44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELA----GAGAAAEGRAG 119
|
90 100 110
....*....|....*....|....*....|....*...
gi 2462517863 1409 KMNFDVSNLKDNN-------EILSQQLFKTESKLNSLE 1439
Cdd:PRK09039 120 ELAQELDSEKQVSaralaqvELLNQQIAALRRQLAALE 157
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1156-1465 |
3.72e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.13 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1156 SLNQEEEKRRNADTLYEKI---REQLRRKEEQY---RKEVE-VKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLS 1228
Cdd:pfam12128 595 WAASEEELRERLDKAEEALqsaREKQAAAEEQLvqaNGELEkASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALA 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1229 REQNARMLQ----DGILTNHLSKQKEIEMAQKKMNSENSHSHEE-----EKDLSHKNSMLQEEIAMLRLEIDTIKNQNQE 1299
Cdd:pfam12128 675 ERKDSANERlnslEAQLKQLDKKHQAWLEEQKEQKREARTEKQAywqvvEGALDAQLALLKAAIAARRSGAKAELKALET 754
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1300 KEKKCFEDLKIVKEKNEDLQKTIKqneeTLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAI 1379
Cdd:pfam12128 755 WYKRDLASLGVDPDVIAKLKREIR----TLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQL 830
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1380 hDRDQSETSKRELELafQRARDECSRLQDKMNFDVSNLKDNNEILSQqlFKTESKLNSLEIEFHHTRDALREKTLGLERV 1459
Cdd:pfam12128 831 -ARLIADTKLRRAKL--EMERKASEKQQVRLSENLRGLRCEMSKLAT--LKEDANSEQAQGSIGERLAQLEDLKLKRDYL 905
|
....*.
gi 2462517863 1460 QKDLSQ 1465
Cdd:pfam12128 906 SESVKK 911
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
96-215 |
3.88e-03 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 41.58 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 96 VTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNED--ISVATKLLLYDANIE 173
Cdd:PHA02946 55 VEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDevIERINLLVQYGAKIN 134
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2462517863 174 AKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSH 215
Cdd:PHA02946 135 NSVDEEGCGPLLACTDPSERVFKKIMSIGFEARIVDKFGKNH 176
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1096-1617 |
3.94e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.12 E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1096 SCERLLELKknHCELLTvkiKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRfslnqEEEKRRNADTlyekir 1175
Cdd:pfam10174 159 SIKKLLEML--QSKGLP---KKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLR-----EELHRRNQLQ------ 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1176 eQLRRKEEQYRKEVEVKQ----QLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQN-ARMLQDGI--LTNHLSKq 1248
Cdd:pfam10174 223 -PDPAKTKALQTVIEMKDtkisSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKShSKFMKNKIdqLKQELSK- 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1249 KEIEMA--QKKM---NSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNED------ 1317
Cdd:pfam10174 301 KESELLalQTKLetlTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEkstlag 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1318 ------------------LQKTIKQNEETLTQTISQYNG---RLSVLTAENAMLNSKL---ENEKQSKERLEAEVESYHS 1373
Cdd:pfam10174 381 eirdlkdmldvkerkinvLQKKIENLQEQLRDKDKQLAGlkeRVKSLQTDSSNTDTALttlEEALSEKERIIERLKEQRE 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1374 RLAAAIhdRDQSETSKRELelafQRARDECSRLQDKM---NFDVSNLKDNNEILSQQLFKTESKLNSLEIEFH-HTRDAL 1449
Cdd:pfam10174 461 REDRER--LEELESLKKEN----KDLKEKVSALQPELtekESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEqKKEECS 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1450 REKTLGLERVQKDLSQTQCQmkEMEQKYQNEQVKVNKYigKQESveerlSQLQSENMLLRQQLDDAHNKADNKEKTVINI 1529
Cdd:pfam10174 535 KLENQLKKAHNAEEAVRTNP--EINDRIRLLEQEVARY--KEES-----GKAQAEVERLLGILREVENEKNDKDKKIAEL 605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1530 ----------QDQFHAIVQKLQAESEKQSL-LLEERNKELISECNhlKERQYQYENEKAEREVVvrqlQQELADTLKKQS 1598
Cdd:pfam10174 606 esltlrqmkeQNKKVANIKHGQQEMKKKGAqLLEEARRREDNLAD--NSQQLQLEELMGALEKT----RQELDATKARLS 679
|
570
....*....|....*....
gi 2462517863 1599 MSEASLEVTSRYRINLEDE 1617
Cdd:pfam10174 680 STQQSLAEKDGHLTNLRAE 698
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
874-1604 |
4.28e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.96 E-value: 4.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 874 EELQQDMQRFKNEIGMLKVEFQALEKEKVQLQK---EVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSG 950
Cdd:TIGR00606 251 KNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKdnsELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEK 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 951 ETDHQQFPRKENKEYASSGPALQMK-EVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLS---EIDEDEGRPT 1026
Cdd:TIGR00606 331 LNKERRLLNQEKTELLVEQGRLQLQaDRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTlviERQEDEAKTA 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1027 KK-----TSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDsvsLLKIQDAALSCERLL 1101
Cdd:TIGR00606 411 AQlcadlQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDR---ILELDQELRKAEREL 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1102 EL--KKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQL- 1178
Cdd:TIGR00606 488 SKaeKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLg 567
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1179 -----RRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSReqnarmLQDGILTNHLSKQKEIEM 1253
Cdd:TIGR00606 568 yfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSS------YEDKLFDVCGSQDEESDL 641
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1254 AQKKmnsenshshEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNE---DLQKTIKQNEETLT 1330
Cdd:TIGR00606 642 ERLK---------EEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEfisDLQSKLRLAPDKLK 712
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1331 QTISQyngrLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD--RDQSETSKRELELAFQRARDECSRLQD 1408
Cdd:TIGR00606 713 STESE----LKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDiqRLKNDIEEQETLLGTIMPEEESAKVCL 788
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1409 K----MNFDVSNLKDNNEILSQQLFKTES--------KLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQK 1476
Cdd:TIGR00606 789 TdvtiMERFQMELKDVERKIAQQAAKLQGsdldrtvqQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE 868
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1477 YQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNK 1556
Cdd:TIGR00606 869 LKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKE 948
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 2462517863 1557 ELISECNHLKER----QYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL 1604
Cdd:TIGR00606 949 KVKNIHGYMKDIenkiQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDM 1000
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1032-1362 |
4.65e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 4.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1032 EKNKVKNQI-QSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLgmeckdSVSLLKIQDAALSCERllELKKNHCEL 1110
Cdd:TIGR02169 696 ELRRIENRLdELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEL------EEDLSSLEQEIENVKS--ELKELEARI 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1111 --LTVKIKKMEDKVNVLQRELSETK-----EIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEE 1183
Cdd:TIGR02169 768 eeLEEDLHKLEEALNDLEARLSHSRipeiqAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE 847
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1184 QyrkEVEVKQQLElslqtlemELRTVKSNLNQVVQERNDAQRQLSREQNArmLQDGILtNHLSKQKEIEMAQKKMNSENS 1263
Cdd:TIGR02169 848 Q---IKSIEKEIE--------NLNGKKEELEEELEELEAALRDLESRLGD--LKKERD-ELEAQLRELERKIEELEAQIE 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1264 HSHEEEKDLSHKNSMLQEEIAmlrlEIDTIKNQNQEkEKKCFEDLKIVKEKNEDLQ-----------KTIKQNEETLtQT 1332
Cdd:TIGR02169 914 KKRKRLSELKAKLEALEEELS----EIEDPKGEDEE-IPEEELSLEDVQAELQRVEeeiralepvnmLAIQEYEEVL-KR 987
|
330 340 350
....*....|....*....|....*....|.
gi 2462517863 1333 ISQYNGRLSVLTAENAMLNSKLEN-EKQSKE 1362
Cdd:TIGR02169 988 LDELKEKRAKLEEERKAILERIEEyEKKKRE 1018
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
95-209 |
5.02e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 41.59 E-value: 5.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 95 VVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIea 174
Cdd:PHA02876 160 IAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRSNI-- 237
|
90 100 110
....*....|....*....|....*....|....*
gi 2462517863 175 kNKDDLTpLLLAVSGKKQQMVEFLIKKKANVNAVD 209
Cdd:PHA02876 238 -NKNDLS-LLKAIRNEDLETSLLLYDAGFSVNSID 270
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1355-1609 |
5.51e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 41.65 E-value: 5.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1355 ENEKQSKERLEAEVESYHSRLAAAIH---DRDQSETSKRELELAFQRARD-ECSRLQDKMNFDVSNLKDNNEIlsQQLFK 1430
Cdd:pfam17380 322 EKARQAEMDRQAAIYAEQERMAMERErelERIRQEERKRELERIRQEEIAmEISRMRELERLQMERQQKNERV--RQELE 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1431 TESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVnkyigkqesvEERLSQLQSEnmLLRQ 1510
Cdd:pfam17380 400 AARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRL----------EEQERQQQVE--RLRQ 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1511 QLDDAHNKADNKEKTVIN---IQDQFHAIVQKlQAESEKQSLLlEERNKELISEcNHLKERQYQ-YENEKAEREVVVRQL 1586
Cdd:pfam17380 468 QEEERKRKKLELEKEKRDrkrAEEQRRKILEK-ELEERKQAMI-EEERKRKLLE-KEMEERQKAiYEEERRREAEEERRK 544
|
250 260
....*....|....*....|...
gi 2462517863 1587 QQELADTLKKQSMSEASLEVTSR 1609
Cdd:pfam17380 545 QQEMEERRRIQEQMRKATEERSR 567
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1462-1631 |
5.90e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.97 E-value: 5.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1462 DLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQ 1541
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1542 AESEKQSLL---------------------LEERNKELISEcnhLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMS 1600
Cdd:COG3883 97 RSGGSVSYLdvllgsesfsdfldrlsalskIADADADLLEE---LKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173
|
170 180 190
....*....|....*....|....*....|.
gi 2462517863 1601 EASLEVTSRYRINLEDETQDLKKKLGQIRNQ 1631
Cdd:COG3883 174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAE 204
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1118-1439 |
6.50e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 41.10 E-value: 6.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1118 MEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLnQEEEKRRNADTLYEKIREQLRR----------KEEQYRK 1187
Cdd:COG5185 259 VEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKI-AEYTKSIDIKKATESLEEQLAAaeaeqeleesKRETETG 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1188 EVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNdaqrqlsREQNARMLQDGILTnhLSKQKEiEMAQKKMNSENShSHE 1267
Cdd:COG5185 338 IQNLTAEIEQGQESLTENLEAIKEEIENIVGEVE-------LSKSSEELDSFKDT--IESTKE-SLDEIPQNQRGY-AQE 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1268 EEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKkcfedlKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAEN 1347
Cdd:COG5185 407 ILATLEDTLKAADRQIEELQRQIEQATSSNEEVSK------LLNELISELNKVMREADEESQSRLEEAYDEINRSVRSKK 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1348 AMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRL--QDKMNFDVSNLKDNNEILS 1425
Cdd:COG5185 481 EDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILalENLIPASELIQASNAKTDG 560
|
330
....*....|....
gi 2462517863 1426 QQLFKTESKLNSLE 1439
Cdd:COG5185 561 QAANLRTAVIDELT 574
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1297-1637 |
6.56e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 41.10 E-value: 6.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1297 NQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVE-----SY 1371
Cdd:COG5185 234 ALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDikkatES 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1372 HSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKM-------NFDVSNLKDNNEI--LSQQLFKTESKLNSLEIEF 1442
Cdd:COG5185 314 LEEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLtenleaiKEEIENIVGEVELskSSEELDSFKDTIESTKESL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1443 HHTRDALREKT-LGLERVQKDLSQTQCQMKEM----EQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHN 1517
Cdd:COG5185 394 DEIPQNQRGYAqEILATLEDTLKAADRQIEELqrqiEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEIN 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1518 KadNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELadtlkkQ 1597
Cdd:COG5185 474 R--SVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENL------I 545
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 2462517863 1598 SMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQPELGSV 1637
Cdd:COG5185 546 PASELIQASNAKTDGQAANLRTAVIDELTQYLSTIESQQA 585
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
1109-1227 |
7.06e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 40.39 E-value: 7.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1109 ELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRfslNQEEEKRRNADTLYEKIREQLRRKEEQYRKE 1188
Cdd:smart00787 147 EGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLK---QLEDELEDCDPTELDRAKEKLKKLLQEIMIK 223
|
90 100 110
....*....|....*....|....*....|....*....
gi 2462517863 1189 VEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 1227
Cdd:smart00787 224 VKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKL 262
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1213-1573 |
8.42e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.88 E-value: 8.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1213 LNQ---VVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSmlQEEIAMLR-L 1288
Cdd:pfam17380 271 LNQllhIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAE--QERMAMEReR 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1289 EIDTIKNQNQEKEKKCFEDLKIVKEKN-----EDLQKTIKQNEETLTQTIsqyngrlsvltaENAMLNSKLENEKQSKER 1363
Cdd:pfam17380 349 ELERIRQEERKRELERIRQEEIAMEISrmrelERLQMERQQKNERVRQEL------------EAARKVKILEEERQRKIQ 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1364 lEAEVESYHSRlaaaihdRDQSETSKRELelafQRARDECSRLQDKMNFDVSNLKDNNEILSQQlfKTESKLNSLEIEFH 1443
Cdd:pfam17380 417 -QQKVEMEQIR-------AEQEEARQREV----RRLEEERAREMERVRLEEQERQQQVERLRQQ--EEERKRKKLELEKE 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1444 HtrdalREKTLGLERVQKDLSQtqcQMKEMEQKYQNEQVKvNKYIGKQesVEERLSQLQSEnmllrqqldDAHNKADNKE 1523
Cdd:pfam17380 483 K-----RDRKRAEEQRRKILEK---ELEERKQAMIEEERK-RKLLEKE--MEERQKAIYEE---------ERRREAEEER 542
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1524 KTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYE 1573
Cdd:pfam17380 543 RKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1172-1325 |
9.05e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 9.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1172 EKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDgiltnhlsKQKEI 1251
Cdd:COG1579 27 KELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEA--------LQKEI 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462517863 1252 EMAQKKMNSENSHSHEEEKDLSHKNSML---QEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQN 1325
Cdd:COG1579 99 ESLKRRISDLEDEILELMERIEELEEELaelEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE 175
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
877-1580 |
9.76e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 40.93 E-value: 9.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 877 QQDMQRFKNEIGMLKVEFQALEKEKVQLQK----------EVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQK 946
Cdd:pfam01576 18 KERQQKAESELKELEKKHQQLCEEKNALQEqlqaetelcaEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 947 RKSGETDHQQFPRKENKEYASSgPALQMKEVKSTEKEKRTSKEsvnspvfgkaslltggLLQVDDDSSlseidedegrpt 1026
Cdd:pfam01576 98 KKKMQQHIQDLEEQLDEEEAAR-QKLQLEKVTTEAKIKKLEED----------------ILLLEDQNS------------ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1027 kKTSNEKNKVKNQIQSMDDvddltqssetasedcelphssyknfmllieQLGMECKDSVSLLKIQDAALSCERLLELKKN 1106
Cdd:pfam01576 149 -KLSKERKLLEERISEFTS------------------------------NLAEEEEKAKSLSKLKNKHEAMISDLEERLK 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1107 HCELLTVKIKKMEDKvnvLQRELSETKEiksqlehQKVEWERELCSLRFSLNQEEEKRRNAdtlyekireQLRRKEEQYR 1186
Cdd:pfam01576 198 KEEKGRQELEKAKRK---LEGESTDLQE-------QIAELQAQIAELRAQLAKKEEELQAA---------LARLEEETAQ 258
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1187 KEVEVKQQLELSLQTLEmelrtVKSNLNQVVQERNDAQRQ---LSREQNA--RMLQDGILT----NHLSKQKEIEMAQ-K 1256
Cdd:pfam01576 259 KNNALKKIRELEAQISE-----LQEDLESERAARNKAEKQrrdLGEELEAlkTELEDTLDTtaaqQELRSKREQEVTElK 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1257 KMNSENSHSHEEE-KDLSHKNSMLQEEIAMlRLEIDTIKNQNQEKEKKCFEdlkivkEKNEDLQKTIKqneeTLTQTISQ 1335
Cdd:pfam01576 334 KALEEETRSHEAQlQEMRQKHTQALEELTE-QLEQAKRNKANLEKAKQALE------SENAELQAELR----TLQQAKQD 402
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1336 YNGRLSVLTAENAMLNSKL-ENEKQSKERLEaevesyhsRLAAAIHDRDQSETSKRELELAFQRARDECSRLQdkmnfdv 1414
Cdd:pfam01576 403 SEHKRKKLEGQLQELQARLsESERQRAELAE--------KLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLE------- 467
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1415 SNLKDNNEILS---QQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQvkvnkyiGKQ 1491
Cdd:pfam01576 468 SQLQDTQELLQeetRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDA-------GTL 540
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462517863 1492 ESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQ----------DQFHAIVQKLQAESEK-QSLLLEERNkelIS 1560
Cdd:pfam01576 541 EALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQqelddllvdlDHQRQLVSNLEKKQKKfDQMLAEEKA---IS 617
|
730 740
....*....|....*....|
gi 2462517863 1561 EcnhlkerQYQYENEKAERE 1580
Cdd:pfam01576 618 A-------RYAEERDRAEAE 630
|
|
| |
