|
Name |
Accession |
Description |
Interval |
E-value |
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-796 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 1392.63 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRG 80
Cdd:cd00764 18 MNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKGGDYIKQAEWESVSNWLQEGGTIIGSARCKEFREREGRLQAAYNLIQRG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV 160
Cdd:cd00764 98 ITNLCVIGGDGSLTGADLFRSEWPSLLEELVKDGKITEEEVAKYQHLNIVGMVGSIDNDFCGTDMTIGTDSALHRICEVV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 161 DAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDT 240
Cdd:cd00764 178 DAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEDGWEDQMCRRLSEHRSRGKRLNIIIVAEGAIDD 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 241 QNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLM 320
Cdd:cd00764 258 QLKPITSEDVKDLVVERLGLDTRVTTLGHVQRGGTPSAFDRILASLMGVEAVMALLEATPDTPACVVSLNGNKAVRLPLM 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 321 ECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNCNVAVINVGAPAAGMNAAVRSAVRVGIA 400
Cdd:cd00764 338 ECVQLTKDVQKAMDEKRFDEAAALRGKSFDKNWNLYKLLAIELPQPLPEKTNLNIAIVNVGAPAAGMNAAVRSAVRYGLA 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 401 DGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGLLEL 480
Cdd:cd00764 418 HGHRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELGTKRTLPKKDLETIAYNFQKYGIDGLIIVGGFEAYKGLLQL 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 481 SAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTItdayksacdmaeargrhqelciplcvvpatisnnvpgte 560
Cdd:cd00764 498 REAREQYEEFCIPMVLIPATVSNNVPGTDFSLGSDTALNAL--------------------------------------- 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 561 islgsdtglnavVETCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTEKMK 640
Cdd:cd00764 539 ------------MKYCDRIKQSASGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVEHLTEKMK 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 641 TTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEARGR 720
Cdd:cd00764 607 TTIGRGLVLRNEKCNENYTTVFTYELYSEEGKGVFDCRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQKLKENYAA 686
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462519634 721 GKKFTTDDSICVLGISKRNVIFQPVAELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHVQPWS 796
Cdd:cd00764 687 GNEFANDPDFNCVNGVKKYAVLFEPVEELKQTTFEHRIPKEQWWLSLRPLLKILAKYKISADISDHGQLEHVTRGQ 762
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
1-779 |
0e+00 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 1264.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRG 80
Cdd:TIGR02478 15 MNAAVRAVVRMAIYVGCRVYAIREGYQGLVDGGDNIEEAQWEDVRGILSLGGTIIGTARCKEFRERPGRLKAARNLVSNG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGANLFRKEWSGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV 160
Cdd:TIGR02478 95 IDALVVIGGDGSLTGADLFREEWPSLLEELVDTGKITAEQAEEHRHLTIVGLVGSIDNDMCGTDMTIGADSALHRICEAI 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 161 DAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDT 240
Cdd:TIGR02478 175 DAISSTAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERPPEEGWEDQLCHKLKRNRKAGKRKTIVIVAEGAIDR 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 241 QNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLM 320
Cdd:TIGR02478 255 DLNPITSEDVKDVLVERLGLDTRITVLGHVQRGGAPSAFDRILATRQGVEAVLAVLESTPETPSPVISLRGNKIVRKPLV 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 321 ECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLNTYKRLAIKLPDDQIPKTNC---NVAVINVGAPAAGMNAAVRSAVRV 397
Cdd:TIGR02478 335 EAVAQTKTVAKAIEEKDFDEAMRLRGREFAENLETFLFLSIPDDDKKLVPSEAsrlRIAIIHVGAPAGGMNAATRSAVRY 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 398 GIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSINALLIIGGFEAYLGL 477
Cdd:TIGR02478 415 ALARGHTVIAIHNGFSGLARHDVRELTWSDVEGWVGEGGSELGTNRSLPGDDLGTIAYYFQQHKIDGLIIIGGFEAFEAL 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 478 LELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITdayksacdmaeargrhqelciplcvvpatisnnvp 557
Cdd:TIGR02478 495 YQLDAAREKYPAFRIPMVVIPATISNNVPGTEYSLGSDTALNEIT----------------------------------- 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 558 gteislgsdtglnavvETCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVEHLTE 637
Cdd:TIGR02478 540 ----------------EYCDNIKQSASASKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLQEDIEHLKE 603
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 638 KMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKLKEA 717
Cdd:TIGR02478 604 TFAEGRAGKLILRNEKASKVYTTDFIARIISEEGKGRFDARTAVLGHMQQGGSPSPFDRVRATRLAIRAVDFIEEKIKAN 683
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462519634 718 RGRGKKFTTDDSICVLGISKRNVIFQPVA-ELKKQTDFEHRIPKEQWWLKLRPLMKILAKYKA 779
Cdd:TIGR02478 684 KHADKLSADDTSAVVIGIRGSNVLFTPVKqLLANETDFEHRRPKNQWWLQLRPLVRILAGRDS 746
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-354 |
1.84e-179 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 517.62 E-value: 1.84e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGgsNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRG 80
Cdd:cd00363 15 MNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEG--DIKELDWESVSDIINRGGTIIGSARCKEFRTEEGRAKAAENLKKHG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGANLFRKEWSGlleelarngqidkeavqKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV 160
Cdd:cd00363 93 IDALVVIGGDGSYTGADLLTEEWPS-----------------KYQGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 161 DAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRARKKRLNIIIVAEGAIDT 240
Cdd:cd00363 156 DRIRDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADEWEEEMVDVIKKRRERGKRHGIVIVAEGAIDF 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 241 QNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLM 320
Cdd:cd00363 236 IPKPITEKLLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNLNENQVVRHPLT 315
|
330 340 350
....*....|....*....|....*....|....
gi 2462519634 321 ECVQMTQDVQkamderrfqdaVRLRGRSFAGNLN 354
Cdd:cd00363 316 EAVNMTKRVG-----------VDLEGRPFKKFAK 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
1-292 |
6.21e-135 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 400.95 E-value: 6.21e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGgsNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRG 80
Cdd:pfam00365 14 MNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEG--DIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGREKIAENLKKLG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGANLFRKEWSglleelarngqidkeavqkyayLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV 160
Cdd:pfam00365 92 IDALVVIGGDGSLTGANKLSEERG----------------------IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 161 DAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEegwEEQMCVKLsENRARKKRLNIIIVAEGAIDT 240
Cdd:pfam00365 150 DRIRDTASSHNRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFD---IEELCEKI-KELRKGKRFSIIVVAEGASDG 225
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2462519634 241 qnkpitsEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAV 292
Cdd:pfam00365 226 -------EFLAKLIEEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKAV 270
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-335 |
9.62e-114 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 347.84 E-value: 9.62e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGgsNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRG 80
Cdd:PRK03202 16 MNAAIRAVVRTAISEGLEVYGIYDGYAGLLEG--DIVKLDLKSVSDIINRGGTILGSARFPEFKDEEGRAKAIENLKKLG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGANLfrkewsglleeLARNGqidkeavqkyayLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV 160
Cdd:PRK03202 94 IDALVVIGGDGSYMGAKR-----------LTEHG------------IPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 161 DAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEegwEEQMCVKLSENRARKKRLNIIIVAEGAIDT 240
Cdd:PRK03202 151 DRLRDTASSHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFD---IEELCAKIKKGRERGKKHAIIVVAEGVMPA 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 241 QNKpitSEKIKElvvtQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDTpacVVSLNGNHAVRLPLM 320
Cdd:PRK03202 228 EEL---AKEIEE----RTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGR---MVGIQNNKIVHVPIE 297
|
330
....*....|....*.
gi 2462519634 321 ECV-QMTQDVQKAMDE 335
Cdd:PRK03202 298 EAVeNMKHPFDKDLYE 313
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-344 |
2.89e-111 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 342.44 E-value: 2.89e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGgsNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRG 80
Cdd:COG0205 16 LNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEG--DIIDLTREDVSGILQRGGTILGSSRSKPFKTEEGREKALENLKKLG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGANLFRKEWSglleelarngqidkeavqkyayLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV 160
Cdd:COG0205 94 IDALVVIGGDGSLDGAAKLAEEYG----------------------IPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 161 DAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEegwEEQMCVKLSENRARKKRLNIIIVAEGAIDT 240
Cdd:COG0205 152 DRLRDTAASHERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFD---LDKLLEKLKERRKRGKGYSIIVVAEGAGDE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 241 QNKPI---------------TSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEatpDTPAC 305
Cdd:COG0205 229 DGEAVleadtdafghvrlggIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLE---GKTGV 305
|
330 340 350
....*....|....*....|....*....|....*....
gi 2462519634 306 VVSLNGNHAVRLPLMECVQMTQDVQKAMDerRFQDAVRL 344
Cdd:COG0205 306 MVGIRRGEIVLVPLEEVANKEKPVDPDSP--LIQLAREL 342
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
1-321 |
3.65e-101 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 314.67 E-value: 3.65e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGgsNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRG 80
Cdd:TIGR02482 14 MNAAIRAVVRTAIYHGFEVYGIRRGYKGLING--KIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVREKAVENLKKLG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGANLFRKEwsglleelarnGQIdkeavqkyaylNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV 160
Cdd:TIGR02482 92 IEGLVVIGGDGSYTGAQKLYEE-----------GGI-----------PVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 161 DAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEegwEEQMCVKLSENRARKKRLNIIIVAEGAIDT 240
Cdd:TIGR02482 150 DKIRDTATSHERAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYD---IDELIQRLKEQHEAGKKHSIIIVAEGNIVG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 241 QNKPItSEKIKELVvtqlGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEatpDTPACVVSLNGNHAVRLPLM 320
Cdd:TIGR02482 227 SAKEV-AKKIEEKT----GIETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLE---GKGGVMIGIQNNKIVTHPIE 298
|
.
gi 2462519634 321 E 321
Cdd:TIGR02482 299 E 299
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
374-708 |
1.03e-96 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 301.95 E-value: 1.03e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 374 NVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGK---YL 450
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKteeGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 451 EEIATQMRTHSINALLIIGGFEAYLGLLELSAAREkheefcVPMVMVPATVSNNVPGSDFSIGADTALNTITDAyksacd 530
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSEERG------IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEA------ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 531 maeargrhqelciplcvvpatisnnvpgteislgsdtglnavvetCDRIKQSASGTkRRVFIIETMGGYCGYLANMGGLA 610
Cdd:pfam00365 149 ---------------------------------------------IDRIRDTASSH-NRVFVVEVMGRHCGWLALMAGLA 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 611 AGADAAYIFEEPFDIRDLQSNVEHLTEKMKTTIqrglVLRNESCSenyTTDFIYQLYsEEGKGvFDCRKNVLGHMQQGGA 690
Cdd:pfam00365 183 GGADAILIPEIPFDIEELCEKIKELRKGKRFSI----IVVAEGAS---DGEFLAKLI-EEGTG-IETRVTVLGHVQRGGT 253
|
330
....*....|....*...
gi 2462519634 691 PSPFDRNFGTKISARAME 708
Cdd:pfam00365 254 PSAFDRILATRLGVKAVE 271
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-333 |
1.76e-88 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 281.99 E-value: 1.76e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGgsNIAEADWESVSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRG 80
Cdd:cd00763 15 MNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAG--DIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEGQAKAIEQLKKHG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGANLfrkewsglleeLARNGqidkeavqkyayLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV 160
Cdd:cd00763 93 IDALVVIGGDGSYMGAMR-----------LTEHG------------FPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 161 DAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEegwEEQMCVKLSENRARKKRLNIIIVAEGAIDt 240
Cdd:cd00763 150 DRIRDTSSSHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFD---REEVANRIKAGIERGKKHAIVVVAEGVYD- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 241 qnkpitSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEAtpdTPACVVSLNGNHAVRLPLM 320
Cdd:cd00763 226 ------VDELAKEIEEATGFETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAG---KGGLAVGIQNEQLVHHDII 296
|
330
....*....|...
gi 2462519634 321 ECVQMTQDVQKAM 333
Cdd:cd00763 297 DAIENMKPFKKDW 309
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
1-323 |
8.64e-73 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 240.67 E-value: 8.64e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYV-GAKVYFIYEGYQGMVDGGSnIAEADWESVSSILQVGGTIIGSARCQAFRT-REGRLKAACNLLQ 78
Cdd:TIGR02483 14 LNAVIRGVVRRAIAEyGWEVIGIRDGWRGLLEGDT-VPLLDLEDVRGILPRGGTILGSSRTNPFKYeEDGDDKIVANLKE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 79 RGITNLCVIGGDGSLTGANlfrkewsglleELARNGqidkeavqkyayLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIE 158
Cdd:TIGR02483 93 LGLDALIAIGGDGTLGIAR-----------RLADKG------------LPVVGVPKTIDNDLEATDYTFGFDTAVEIATE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 159 VVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEegwEEQMCVKLSENRARKKRLNIIIVAEGA- 237
Cdd:TIGR02483 150 ALDRLHTTAESHHRVMVVEVMGRHAGWIALHSGIAGGADVILIPEIPFD---IDSVCEKVRERFARGKRFAIVVVAEGAk 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 238 -------IDTQNKPI--------TSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAVIALLEATPDT 302
Cdd:TIGR02483 227 pkggemvVQEGVKDAfghvrlggIGNWLAEEIERRTGIETRATVLGHLQRGGSPSAFDRVLATRFGVAAVDLVHEGQFGH 306
|
330 340
....*....|....*....|.
gi 2462519634 303 pacVVSLNGNHAVRLPLMECV 323
Cdd:TIGR02483 307 ---MVALRGTDIVYVPIAEAV 324
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
1-292 |
3.26e-50 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 180.27 E-value: 3.26e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVR--MGIYvGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQ---AFRTREGRLKAACN 75
Cdd:PRK14071 19 LNAVIRAVVHraRGTY-GWEVIGIRDATQGLMARPPQYIELDLDQVDDLLRMGGTILGTTNKGdpfAFPMPDGSLRDRSQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 76 -----LLQRGITNLCVIGGDGSLtganlfrkewsGLLEELARNGQIdkeavqkyaylNVVGMVGSIDNDFCGTDMTIGTD 150
Cdd:PRK14071 98 eiidgYHSLGLDALIGIGGDGSL-----------AILRRLAQQGGI-----------NLVGIPKTIDNDVGATEVSIGFD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 151 SALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPpeegWE-EQMCVKLSENRARKKRLN 229
Cdd:PRK14071 156 TAVNIATEALDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIP----YTlENVCKKIRERQEEGKNFC 231
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462519634 230 IIIVAEGAIDTQNKPITSEK-------------IKELVVTQLGYDTRVTILGHVQRGGTPSAFDRILASRMGVEAV 292
Cdd:PRK14071 232 LVVVSEAVRTEEGEQVTKTQalgedryggigqyLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAV 307
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
374-710 |
2.04e-44 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 163.32 E-value: 2.04e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 374 NVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGK---YL 450
Cdd:COG0205 3 RIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKteeGR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 451 EEIATQMRTHSINALLIIGGfeaylgllE--LSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDAyksa 528
Cdd:COG0205 83 EKALENLKKLGIDALVVIGG--------DgsLDGAAKLAEEYGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEA---- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 529 cdmaeargrhqelciplcvvpatisnnvpgteislgsdtglnavvetCDRIKQSASGTkRRVFIIETMGGYCGYLANMGG 608
Cdd:COG0205 151 -----------------------------------------------IDRLRDTAASH-ERVFVVEVMGRHAGWLALAAG 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 609 LAAGADAAYIFEEPFDIRDLqsnVEHLTEKMKTTIQRGLVL--------RNESCSENYTTDFIYQLYSEEGKGV------ 674
Cdd:COG0205 183 LAGGADLILIPEVPFDLDKL---LEKLKERRKRGKGYSIIVvaegagdeDGEAVLEADTDAFGHVRLGGIGEYLakeiee 259
|
330 340 350
....*....|....*....|....*....|....*....
gi 2462519634 675 ---FDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWI 710
Cdd:COG0205 260 rtgIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELL 298
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
375-767 |
4.19e-44 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 161.81 E-value: 4.19e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 375 VAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRvLPGKYLEEI- 453
Cdd:cd00763 3 IGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSAR-FPEFKDEEGq 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 454 ---ATQMRTHSINALLIIGGFEAYLGLLELSaarekheEFCVPMVMVPATVSNNVPGSDFSIGADTALNTitdayksacd 530
Cdd:cd00763 82 akaIEQLKKHGIDALVVIGGDGSYMGAMRLT-------EHGFPCVGLPGTIDNDIPGTDYTIGFDTALNT---------- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 531 maeargrhqelciplcvvpatisnnvpgteislgsdtglnaVVETCDRIKQSASgTKRRVFIIETMGGYCGYLANMGGLA 610
Cdd:cd00763 145 -----------------------------------------VVEAIDRIRDTSS-SHQRISVVEVMGRHCGDIALAAGIA 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 611 AGADAAYIFEEPFDIRDLQSNVEHLTEKMKttiQRGLVLRNESCsenYTTDFIYQLYSEEGKgvFDCRKNVLGHMQQGGA 690
Cdd:cd00763 183 GGAEFIVIPEAEFDREEVANRIKAGIERGK---KHAIVVVAEGV---YDVDELAKEIEEATG--FETRATVLGHIQRGGS 254
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462519634 691 PSPFDRNFGTKISARAMEWITAklkearGRGkkfttddSICVlGISKRNVIFQPVAELkkqtdFEHRIPKEQWWLKL 767
Cdd:cd00763 255 PTAFDRILASRMGAYAVELLLA------GKG-------GLAV-GIQNEQLVHHDIIDA-----IENMKPFKKDWLAL 312
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
384-708 |
1.18e-42 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 157.55 E-value: 1.18e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 384 AAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLE---EIATQMRTH 460
Cdd:PRK03202 13 APGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEEgraKAIENLKKL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 461 SINALLIIGGFEAYLGLLELSaarekheEFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDAyksacdmaeargrhqe 540
Cdd:PRK03202 93 GIDALVVIGGDGSYMGAKRLT-------EHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEA---------------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 541 lcIplcvvpatisnnvpgteislgsdtglnavvetcDRIKQSASgTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFE 620
Cdd:PRK03202 150 --I---------------------------------DRLRDTAS-SHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPE 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 621 EPFDIRDLQSNVEHLTEKMKttiQRGLVLRNES-CSENYTTDFIyqlyseEGKGVFDCRKNVLGHMQQGGAPSPFDRNFG 699
Cdd:PRK03202 194 VPFDIEELCAKIKKGRERGK---KHAIIVVAEGvMPAEELAKEI------EERTGLETRVTVLGHIQRGGSPTAFDRVLA 264
|
....*....
gi 2462519634 700 TKISARAME 708
Cdd:PRK03202 265 SRMGAHAVE 273
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
374-748 |
1.23e-42 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 158.23 E-value: 1.23e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 374 NVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRvLPGKYLEEI 453
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSAR-CKEFRTEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 454 ----ATQMRTHSINALLIIGGFEAYLGLLEL-SAAREKHEEFcvPMVMVPATVSNNVPGSDFSIGADTALNTItdayksa 528
Cdd:cd00363 81 rakaAENLKKHGIDALVVIGGDGSYTGADLLtEEWPSKYQGF--NVIGLPGTIDNDIKGTDYTIGFDTALKTI------- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 529 cdmaeargrhqelciplcvvpatisnnvpgteislgsdtglnavVETCDRIKQSASgTKRRVFIIETMGGYCGYLANMGG 608
Cdd:cd00363 152 --------------------------------------------VEAIDRIRDTAS-SHQRTFVVEVMGRHCGDIALEAG 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 609 LAAGADAAYIFEEPFDIRDlqsnVEHLTEKMKTTIQRG----LVLRNEScsenyTTDFIYQLYSEEG-------KGVFDC 677
Cdd:cd00363 187 LATGADIIFIPEEPAADEW----EEEMVDVIKKRRERGkrhgIVIVAEG-----AIDFIPKPITEKLlaklveeRLGFDT 257
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462519634 678 RKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITAKlkeargrgkkfTTDDSICVLGISKRNVIFQPVAEL 748
Cdd:cd00363 258 RATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEG-----------TGGTPVGIQNLNENQVVRHPLTEA 317
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
374-752 |
6.69e-38 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 151.72 E-value: 6.69e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 374 NVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKGQ--IKEIGWTDVGGWTGQGGSILGTKRVL-----P 446
Cdd:TIGR02478 2 RIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDGGdnIEEAQWEDVRGILSLGGTIIGTARCKefrerP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 447 GKYLEeiATQMRTHSINALLIIGGFEAylglleLSAAREKHEEFcvpmvmvPATVSNNVpgsdfsigadtALNTITdayk 526
Cdd:TIGR02478 82 GRLKA--ARNLVSNGIDALVVIGGDGS------LTGADLFREEW-------PSLLEELV-----------DTGKIT---- 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 527 sacdmAEARGRHQELCIplCVVPATISNNVPGTEISLGSDTGLNAVVETCDRIKQSASGTKrRVFIIETMGGYCGYLANM 606
Cdd:TIGR02478 132 -----AEQAEEHRHLTI--VGLVGSIDNDMCGTDMTIGADSALHRICEAIDAISSTAQSHQ-RAFVVEVMGRHCGYLALM 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 607 GGLAAGADAAYIFEEPFDirdlQSNVEHLTEKMKTTIQRG----LVLRNE----SCSENYTTDFIYQLYSEEGKgvFDCR 678
Cdd:TIGR02478 204 AAIATGADYVFIPERPPE----EGWEDQLCHKLKRNRKAGkrktIVIVAEgaidRDLNPITSEDVKDVLVERLG--LDTR 277
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462519634 679 KNVLGHMQQGGAPSPFDRNFGTKISARAmewITAKLKeargrgkkfTTDDSI-CVLGISKRNVIFQPVAELKKQT 752
Cdd:TIGR02478 278 ITVLGHVQRGGAPSAFDRILATRQGVEA---VLAVLE---------STPETPsPVISLRGNKIVRKPLVEAVAQT 340
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
375-794 |
4.79e-33 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 136.49 E-value: 4.79e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 375 VAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDGFDGFAKG--QIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLE- 451
Cdd:cd00764 6 IAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKGgdYIKQAEWESVSNWLQEGGTIIGSARCKEFREREg 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 452 --EIATQMRTHSINALLIIGGFEAylglleLSAAREKHEEFcvpmvmvPATVSNNVPGSDFSigadtalntitdayksac 529
Cdd:cd00764 86 rlQAAYNLIQRGITNLCVIGGDGS------LTGADLFRSEW-------PSLLEELVKDGKIT------------------ 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 530 dmAEARGRHQELCIplCVVPATISNNVPGTEISLGSDTGLNAVVETCDRIKQSASgTKRRVFIIETMGGYCGYLANMGGL 609
Cdd:cd00764 135 --EEEVAKYQHLNI--VGMVGSIDNDFCGTDMTIGTDSALHRICEVVDAITTTAQ-SHQRTFVLEVMGRHCGYLALVSGL 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 610 AAGADAAYIFEEPFDiRDLQsnvEHLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGV------FDCRKNVLG 683
Cdd:cd00764 210 ATGADWIFIPERPPE-DGWE---DQMCRRLSEHRSRGKRLNIIIVAEGAIDDQLKPITSEDVKDLvverlgLDTRVTTLG 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 684 HMQQGGAPSPFDRNFGTKisaRAMEWITAKLKEargrgkkfTTDDSICVLGISKRNVIFQPVAELKKQTdfeHRIPKEQW 763
Cdd:cd00764 286 HVQRGGTPSAFDRILASL---MGVEAVMALLEA--------TPDTPACVVSLNGNKAVRLPLMECVQLT---KDVQKAMD 351
|
410 420 430
....*....|....*....|....*....|..
gi 2462519634 764 WLKLRPLMKILAK-YKASYDVSDSGQLEHVQP 794
Cdd:cd00764 352 EKRFDEAAALRGKsFDKNWNLYKLLAIELPQP 383
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
1-241 |
3.89e-24 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 106.67 E-value: 3.89e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVVRMGIYV-GAK-VYFIYEGYQGMVDGGSniAEADWESVSSILQVGGTIIGSARcqafrTREGRLKAACNLLQ 78
Cdd:PTZ00286 102 LNVVIRELVMNLINNyGVKtIYGAKYGYKGLYKEDW--IKLDPKDVKTIHRLGGTILGSSR-----GGFDPKVMVDTLIR 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 79 RGITNLCVIGGDGSLTGANlfrkewsglleelarngQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIE 158
Cdd:PTZ00286 175 HGINILFTLGGDGTHRGAL-----------------AIYKELRRRKLNISVVGIPKTIDNDIPIIDESFGFQTAVEEAQN 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 159 VVDAIMTTAQSHQRTF-VLEVMGRHCGYLALVSALACG-ADWVFLPESPpeegWEEQMCVKLSENRARKKRLNIIIVAEG 236
Cdd:PTZ00286 238 AIRAAYVEAKSAKNGVgIVKLMGRDSGFIALHASVASAdVNVCLIPEFD----IPLEGVLEYIEQRLQKKGHCVIVVAEG 313
|
....*
gi 2462519634 237 AIDTQ 241
Cdd:PTZ00286 314 AGQSL 318
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
2-237 |
1.50e-17 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 86.08 E-value: 1.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 2 NAAVRAVVR--MGIYVGAKVYFIYEGYQGMV-DGGSNIAEADWESVSSILQVGGTIIGSARcqafrtreGRLKAAC---N 75
Cdd:PRK06830 96 NDVIRAIVLelHHHYGVRRILGIRYGYQGLIpRYGHDPVELTPEVVADIHEFGGTILGSSR--------GPQDPEEivdT 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 76 LLQRGITNLCVIGGDGSLTGAnlfrkewSGLLEELARNGqidkeavQKYAylnVVGMVGSIDNDFCGTDMTIGTDSALHR 155
Cdd:PRK06830 168 LERMNINILFVIGGDGTLRGA-------SAIAEEIERRG-------LKIS---VIGIPKTIDNDINFIQKSFGFETAVEK 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 156 IIEVVDAIMTTAQSHQRTFVL-EVMGRHCGYLALVSALACG-ADWVFLPESPPEEGWEEQMCVKLsENRARKKRLNIIIV 233
Cdd:PRK06830 231 ATEAIRCAHVEANGAPNGIGLvKLMGRHSGFIAAYAALASKdVNFVLIPEVPFDLEGPNGLLAAL-EKRLAERGHAVIVV 309
|
....
gi 2462519634 234 AEGA 237
Cdd:PRK06830 310 AEGA 313
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
119-297 |
3.01e-15 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 78.75 E-value: 3.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 119 EAVQKYAY-LNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVV-----D-AIMTTaqsHQRTFVLEVMGRHCGYLALVSA 191
Cdd:PRK14072 124 QLAKKMGYpIRCIGIPKTIDNDLPGTDHCPGFGSAAKYIATSVleaalDvAAMAN---TSKVFILEVMGRHAGWLAAAAA 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 192 LAC-----GADWVFLPESPPEegwEEQMCVKLSENRARKKRLnIIIVAEGAIDTQNKPITSEK----------------- 249
Cdd:PRK14072 201 LAKqnpddAPHLIYLPERPFD---EEKFLADVRAIVKRYGYC-VVVVSEGIRDADGKFIAEAGlaedafghaqlggvapv 276
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2462519634 250 IKELVVTQLGYDTRVTILGHVQR--GGTPSAFDRILASRMGVEAVIALLE 297
Cdd:PRK14072 277 LANLIKEKLGKKVHWAVLDYLQRaaRHIASKTDVEEAYAVGKAAVEYALA 326
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
18-237 |
4.39e-14 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 75.55 E-value: 4.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 18 KVYFIYEGYQGMVdgGSNIAEADWESVSSILQVGGTIIGSARcqafrTREGRLKAACNLLQRGITNLCVIGGDGSLTGAN 97
Cdd:PLN02564 121 RILGIDGGYRGFY--SRNTIPLTPKVVNDIHKRGGTILGTSR-----GGHDTSKIVDSIQDRGINQVYIIGGDGTQKGAS 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 98 LfrkewsgLLEELARNGqidkeavQKYAylnVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQS-HQRTFVL 176
Cdd:PLN02564 194 V-------IYEEIRRRG-------LKVA---VAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESvENGIGLV 256
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462519634 177 EVMGRHCGYLALVSALAC-GADWVFLPESP----PEEGWEEQMCVKLSENRARkkrlnIIIVAEGA 237
Cdd:PLN02564 257 KLMGRYSGFIAMYATLASrDVDCCLIPESPfyleGKGGLFEFIEKRLKENGHM-----VIVVAEGA 317
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
375-712 |
1.04e-13 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 73.57 E-value: 1.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 375 VAVINVGAPAAGMNAAVRSAVRVGIAD-GHRMLAIYDGFDGFAKG--QIKEIGWTDVGGWTGQGGSILGT-KRVLPGKY- 449
Cdd:PRK14071 7 IGILTSGGDCAGLNAVIRAVVHRARGTyGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTtNKGDPFAFp 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 450 LEEIATQMRTHSInalliIGGFEAyLGLLELsaarekheefcvpmvmvpatvsnnvpgsdFSIGADTAlntitdayksac 529
Cdd:PRK14071 87 MPDGSLRDRSQEI-----IDGYHS-LGLDAL-----------------------------IGIGGDGS------------ 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 530 dMAEARGRHQELCIPLCVVPATISNNVPGTEISLGSDTGLNAVVETCDRIKQSASgTKRRVFIIETMGGYCGYLANMGGL 609
Cdd:PRK14071 120 -LAILRRLAQQGGINLVGIPKTIDNDVGATEVSIGFDTAVNIATEALDRLHFTAA-SHNRVMILEVMGRDAGHIALAAGI 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 610 AAGADAAYIFEEPFDIrdlqsnvEHLTEKMKTTIQRG----LVLRNESC----SENYTTDF---------IYQLYSEE-- 670
Cdd:PRK14071 198 AGGADVILIPEIPYTL-------ENVCKKIRERQEEGknfcLVVVSEAVrteeGEQVTKTQalgedryggIGQYLAEQia 270
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2462519634 671 GKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISARAMEWITA 712
Cdd:PRK14071 271 ERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQ 312
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
1-329 |
2.84e-12 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 69.45 E-value: 2.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 1 MNAAVRAVV-RMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWESVSSILQVGGTIIGSARCQAfRTREgrlkAACNLLQR 79
Cdd:PLN02884 68 LNDVIRQIVfTLEIYGVKNIVGIPFGYRGFFEKGLSEMPLSRKVVQNIHLSGGSLLGVSRGGA-KTSD----IVDSIEAR 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 80 GITNLCVIGGDGSLTGANLfrkewsglleelarngqIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEV 159
Cdd:PLN02884 143 GINMLFVLGGNGTHAGANA-----------------IHNECRKRKMKVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQRA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 160 VDAIMTTAQSHQRTF-VLEVMGRHCGYLALVSALACG-ADWVFLPESPPEEGWEEQMCVKLsENRARKKRLNIIIVAEGA 237
Cdd:PLN02884 206 INSAYIEAHSAYHGIgLVKLMGRSSGFIAMHASLASGqVDICLIPEVPFTLDGPNGVLRHL-EHLIETKGSAVVCVAEGA 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 238 -IDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPS-----------------AFDRILASRMGVEAVIAlleAT 299
Cdd:PLN02884 285 gQDLLQKTNATDASGNPVLGDIGVHLQQEIKKHFKDIGVPAdvkyidptymiracranASDAILCTVLGQNAVHG---AF 361
|
330 340 350
....*....|....*....|....*....|
gi 2462519634 300 PDTPACVVSLNGNHAVRLPLMECVQMTQDV 329
Cdd:PLN02884 362 AGFSGITVGICNTHYVYLPIPEVIAYPRRV 391
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
25-193 |
3.64e-09 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 59.64 E-value: 3.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 25 GYQGMVDGGS-NIAEADWESVSSILQVGGTIIGSARCQAFRT---------REGR--LKAACNLLQR-GITNLCVIGGDG 91
Cdd:PRK06555 44 GYQGLLLGDSiEITPAVRANAGLLHRYGGSPIGNSRVKLTNVadcvkrglvKEGEnpLKVAAERLAAdGVDILHTIGGDD 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 92 SLTGAnlfrkewSGLLEELARNGqidkeavqkYAyLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQ 171
Cdd:PRK06555 124 TNTTA-------ADLAAYLAENG---------YD-LTVVGLPKTIDNDVVPIRQSLGAWTAAEQGARFFDNVINEHSANP 186
|
170 180
....*....|....*....|...
gi 2462519634 172 RTFVL-EVMGRHCGYLALVSALA 193
Cdd:PRK06555 187 RMLIIhEVMGRNCGWLTAATARA 209
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
375-536 |
8.53e-09 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 58.52 E-value: 8.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 375 VAVINVGAPAAGMNAAVRSAVRVGIADGH--RMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRvlPGKYLEE 452
Cdd:PTZ00286 90 AGIVTCGGLCPGLNVVIRELVMNLINNYGvkTIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSR--GGFDPKV 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 453 IATQMRTHSINALLIIGGFEAYLGLLELS--AAREKHEefcVPMVMVPATVSNNVPGSDFSIGADTALNTITDAYKSAcd 530
Cdd:PTZ00286 168 MVDTLIRHGINILFTLGGDGTHRGALAIYkeLRRRKLN---ISVVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAA-- 242
|
....*.
gi 2462519634 531 MAEARG 536
Cdd:PTZ00286 243 YVEAKS 248
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
374-528 |
9.19e-06 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 48.65 E-value: 9.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 374 NVAVINVGAPAAGMNAAVRSAV-RVGIADGHRMLAIYDGFDGFAKGQIKEIGWTD--VGGWTGQGGSILGTKRvlPGKYL 450
Cdd:PLN02884 55 KAAIVTCGGLCPGLNDVIRQIVfTLEIYGVKNIVGIPFGYRGFFEKGLSEMPLSRkvVQNIHLSGGSLLGVSR--GGAKT 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 451 EEIATQMRTHSINALLIIGGFEAYLGllelsaAREKHEEfC------VPMVMVPATVSNNVPGSDFSIGADTALNTITDA 524
Cdd:PLN02884 133 SDIVDSIEARGINMLFVLGGNGTHAG------ANAIHNE-CrkrkmkVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQRA 205
|
....
gi 2462519634 525 YKSA 528
Cdd:PLN02884 206 INSA 209
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
81-239 |
6.27e-04 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 43.49 E-value: 6.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 81 ITNLCVIGGDGSLTGAnlfrkewsGLLEELARNGQIDkeavqkyayLNVVGMVGSIDNDFC--GTDMTIGTDSALHRIIE 158
Cdd:PTZ00287 272 LNGLVIIGGDGSNSNA--------ALISEYFAERQIP---------ISIIGIPKTIDGDLKseAIEISFGFDTATKTYSE 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 159 VVDAIMTTAQS-HQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVK-----LSENRARKKRLNIII 232
Cdd:PTZ00287 335 VIGNLCTDVKTgHNVYHVVRVMGRSASHVVLECALQTRPNIVLIGEEVEKENLSLKDIVSnivntILKRRSLNKNYGVIL 414
|
....*..
gi 2462519634 233 VAEGAID 239
Cdd:PTZ00287 415 IPEGLIE 421
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
386-517 |
4.92e-03 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 40.12 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 386 GMNAAVRSAVrVGIADG---HRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRvlPGKYLEEIATQMRTHSI 462
Cdd:PLN02564 101 GLNTVIREIV-CGLSYMygvTRILGIDGGYRGFYSRNTIPLTPKVVNDIHKRGGTILGTSR--GGHDTSKIVDSIQDRGI 177
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462519634 463 NALLIIGGFEAYLGllelsaAREKHEE-----FCVPMVMVPATVSNNVPGSDFSIGADTA 517
Cdd:PLN02564 178 NQVYIIGGDGTQKG------ASVIYEEirrrgLKVAVAGIPKTIDNDIPVIDKSFGFDTA 231
|
|
| |
