|
Name |
Accession |
Description |
Interval |
E-value |
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
338-774 |
5.03e-137 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 411.26 E-value: 5.03e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 338 LAGVYALIIFEIVHRTLAAMLGSLAALAALaVIGDRPSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYRL 417
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLVILG-LATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 418 SRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSnqe 497
Cdd:cd01116 80 SKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGS--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 498 lrKMGLDFAGFTAHMFIGICLVLLVCFPLLRLLYWNRKLYNKEPSEIvelkheihvwrltaqrispasreetavrrlllg 577
Cdd:cd01116 157 --AAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLA--------------------------------- 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 578 kvlalehllarrlhtfhrqisqedknwetnIQELQKKHRISDGILLAKCLTVLGFVIFMFFLNSFVpgiHLDLGWIAILG 657
Cdd:cd01116 202 ------------------------------LAELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSPL---GVSLGWIALLG 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 658 AIWLLILADIHDFEIILHRVEWATLLFFAALFVLME-------------------------------------------- 693
Cdd:cd01116 249 ALLLLLLADKLDFEDVLSRVEWDTLLFFAGLFVLVGgleelgiiewiaellvgvilgriavavililwisallsafidni 328
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 694 ------IPVLLNLSHdpEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMVVSCT 767
Cdd:cd01116 329 pvtatmIPIVKDLAS--QLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWEFLKVGFPIMLVSLI 406
|
....*..
gi 2462544404 768 VGMCYLL 774
Cdd:cd01116 407 LATVYLL 413
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
330-778 |
1.32e-84 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 275.08 E-value: 1.32e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 330 QVTIATAILAGVYALIIFEI--VHRTLAAMLGSLAALAALAVigdrpSLTHVVEWIDFETLALLFGMMILVAIFSETGFF 407
Cdd:COG1055 1 MMILALAIFVLTYLLIILEPrgLNRAVAALLGAALLLLLGVV-----SLEDALEAIDWNTILFLLGMMIIVAILDESGFF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 408 DYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDP 487
Cdd:COG1055 76 EWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 488 PNVIIVSnqelrKMGLDFAGFTAHMFIGICLVLLVCFPLLRLLYwnRKLYNKEPSEIVELKHEIHVWRltaqrispasre 567
Cdd:COG1055 156 TNIMIAS-----AGGLSFLDFLANLFPPSLVSLLVTLLVLYLLF--RKELPAAPDLEDDPKEAIKDRR------------ 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 568 etavrrlllgkvlalehllarrlhtfhrqisqedknwetniqelqkkhrisdgiLLAKCLTVLGFVIFMFFLNSFvpgIH 647
Cdd:COG1055 217 ------------------------------------------------------LLRISLLVLALLLVGFVLHSF---LG 239
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 648 LDLGWIAILGAIWLLILADIHDFEiILHRVEWATLLFFAALFVLME---------------------------------- 693
Cdd:COG1055 240 LPPALIALLGAAVLLLLARVDVRE-VLKKVDWSTLLFFIGLFVVVGglentglldllaellasltggnlllaallilwls 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 694 ---------IPV---LLNLSHDPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPM 761
Cdd:COG1055 319 ailsavvdnVPLvaaLLPLIPDLGATGNPEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFGEFLKVGLPL 398
|
490
....*....|....*..
gi 2462544404 762 MVVSCTVGMCYLLVAHV 778
Cdd:COG1055 399 TLLTLLIALLYLLLLYF 415
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
342-694 |
1.96e-51 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 182.90 E-value: 1.96e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 342 YALIIFEIVHRTLAAMLGSLAALAALAVigdrpSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGR 421
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVL-----TPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 422 VWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNqelrkM 501
Cdd:pfam03600 76 PRRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASA-----L 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 502 GLDFAGFTAHMFIGICLVLLV-CFPLLRLLYWNRKLYNKEPSEIVELKheihvwrltaqrispasreetavrrlllgkvl 580
Cdd:pfam03600 151 GLSFGDFGFFMFPPVGVALLLvGLLPLLLIFRKLLPVRKEEEAELEEL-------------------------------- 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 581 alehllarrlhtfhrqisqedknwetniqelqKKHRISDGILLAKCLTVLGFVIFMFFLNSfvpgihldlgwIAILGAIW 660
Cdd:pfam03600 199 --------------------------------RKRAIKDKLLLAISALVLALVILGFLLLS-----------VLALAGAL 235
|
330 340 350
....*....|....*....|....*....|....
gi 2462544404 661 LLILADIHDFEIILHRVEWATLLFFAALFVLMEI 694
Cdd:pfam03600 236 LLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGA 269
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
383-770 |
3.05e-17 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 85.43 E-value: 3.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 383 IDFETLALLFGMMILVAIFSETGFFDYCA-VKAYRLSRGRvwAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLN 461
Cdd:PLN00136 61 IDLPILGLLFATMVVGSYLKNAGMFKHLGrLLAWRSQGGR--DLLCRVCVVTALASALFTNDTCCVVLTEFVLELAAERN 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 462 LDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLdFAGFTAHMFIG--ICLVLLVCfpllrlLYWNRKLYNK 539
Cdd:PLN00136 139 LPAKPFLLALASSANIGSSATPIGNPQNLVIAFNSKITFPKF-LLGILPAMLAGmaVNMVMLLC------MYWKDLDGGA 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 540 EPSEIVELKHEIHVWRLTAQRIS-PASREETAVRRLLLGKVLALEHLLARRLHTFHRqisqedknWETNIQELQKKHRIS 618
Cdd:PLN00136 212 ELSVDGKQMEAVEEGRSPASAKStKQQSPALLQAGLNGDGNGDMSSMMSENISTKHP--------WFMQCTEHRRKLFLK 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 619 DgilLAKCLTVLGFVIFMFFLNsfvpgihldLGWIAILGAIwLLILADIHDFEIILHRVEWATLLFFAALFV-------- 690
Cdd:PLN00136 284 S---FAYVVTVGMVVAYMVGLN---------MSWTAITTAI-ALVVVDFRDAEPCLDTVSYSLLVFFSGMFItvsgfnkt 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 691 -----------------------LMEIPVLL--NL-SHDPEVGLPAPPLMYA---------------LAFGACLGGNGTL 729
Cdd:PLN00136 351 glpgaiwnfmapyskvnsvggisVLSVIILLlsNLaSNVPTVLLMGDEVAAAaalispaavtrswllLAWVSTVAGNLSL 430
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2462544404 730 IGASAN-VVC--AGIAEQHGYGFSFMEFFRLGFPMMVVSCTVGM 770
Cdd:PLN00136 431 LGSAANlIVCeqARRAPRNAYDLTFWQHIVFGVPSTLIVTAIGI 474
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
376-527 |
4.12e-05 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 46.95 E-value: 4.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 376 LTHVVEW-------IDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIM--LCLIAAVLSAFLDNVTTM 446
Cdd:TIGR00785 285 FLGIVTWkdiqknkVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLvlVVLFYIILYFFASNTAHT 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 447 LLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVII-----VSNQELRKMGLDFAgftahmFIGICLVLL 521
Cdd:TIGR00785 365 AALVPIFFSVASAQGIPLELLALALALSASLMGFLTPYATPPNAIAygsgyVKIKDMWRVGAIIG------IVGLIVLLL 438
|
....*.
gi 2462544404 522 VCFPLL 527
Cdd:TIGR00785 439 VGTLWW 444
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
338-774 |
5.03e-137 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 411.26 E-value: 5.03e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 338 LAGVYALIIFEIVHRTLAAMLGSLAALAALaVIGDRPSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYRL 417
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLVILG-LATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 418 SRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSnqe 497
Cdd:cd01116 80 SKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGS--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 498 lrKMGLDFAGFTAHMFIGICLVLLVCFPLLRLLYWNRKLYNKEPSEIvelkheihvwrltaqrispasreetavrrlllg 577
Cdd:cd01116 157 --AAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLA--------------------------------- 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 578 kvlalehllarrlhtfhrqisqedknwetnIQELQKKHRISDGILLAKCLTVLGFVIFMFFLNSFVpgiHLDLGWIAILG 657
Cdd:cd01116 202 ------------------------------LAELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSPL---GVSLGWIALLG 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 658 AIWLLILADIHDFEIILHRVEWATLLFFAALFVLME-------------------------------------------- 693
Cdd:cd01116 249 ALLLLLLADKLDFEDVLSRVEWDTLLFFAGLFVLVGgleelgiiewiaellvgvilgriavavililwisallsafidni 328
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 694 ------IPVLLNLSHdpEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMVVSCT 767
Cdd:cd01116 329 pvtatmIPIVKDLAS--QLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWEFLKVGFPIMLVSLI 406
|
....*..
gi 2462544404 768 VGMCYLL 774
Cdd:cd01116 407 LATVYLL 413
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
330-778 |
1.32e-84 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 275.08 E-value: 1.32e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 330 QVTIATAILAGVYALIIFEI--VHRTLAAMLGSLAALAALAVigdrpSLTHVVEWIDFETLALLFGMMILVAIFSETGFF 407
Cdd:COG1055 1 MMILALAIFVLTYLLIILEPrgLNRAVAALLGAALLLLLGVV-----SLEDALEAIDWNTILFLLGMMIIVAILDESGFF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 408 DYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDP 487
Cdd:COG1055 76 EWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 488 PNVIIVSnqelrKMGLDFAGFTAHMFIGICLVLLVCFPLLRLLYwnRKLYNKEPSEIVELKHEIHVWRltaqrispasre 567
Cdd:COG1055 156 TNIMIAS-----AGGLSFLDFLANLFPPSLVSLLVTLLVLYLLF--RKELPAAPDLEDDPKEAIKDRR------------ 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 568 etavrrlllgkvlalehllarrlhtfhrqisqedknwetniqelqkkhrisdgiLLAKCLTVLGFVIFMFFLNSFvpgIH 647
Cdd:COG1055 217 ------------------------------------------------------LLRISLLVLALLLVGFVLHSF---LG 239
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 648 LDLGWIAILGAIWLLILADIHDFEiILHRVEWATLLFFAALFVLME---------------------------------- 693
Cdd:COG1055 240 LPPALIALLGAAVLLLLARVDVRE-VLKKVDWSTLLFFIGLFVVVGglentglldllaellasltggnlllaallilwls 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 694 ---------IPV---LLNLSHDPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPM 761
Cdd:COG1055 319 ailsavvdnVPLvaaLLPLIPDLGATGNPEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFGEFLKVGLPL 398
|
490
....*....|....*..
gi 2462544404 762 MVVSCTVGMCYLLVAHV 778
Cdd:COG1055 399 TLLTLLIALLYLLLLYF 415
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
342-773 |
2.01e-74 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 247.16 E-value: 2.01e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 342 YALIIFEIVHRTLAAMLGSLAALAALAVigdrpSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGR 421
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVV-----SPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 422 VWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQelrkm 501
Cdd:cd00625 76 RRLLLLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPPVPLLLALAFAANIGGAATPIGNPPNLIIASLS----- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 502 GLDFAGFTAHMFIGICLVLLVCFPLLRLLYWnrklynkepseivelkheihvwrltaqrispasreetavrrlllgkvla 581
Cdd:cd00625 151 GLGFLDFLAFMAPPALGLLLLLLGLLYLLFR------------------------------------------------- 181
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 582 lehllarrlhtfhRQISQEDKNWETNIQELQKKHRISDGILLAKCLTVLGFVIFMFFLnsfvpgihLDLGWIAILGAIWL 661
Cdd:cd00625 182 -------------KKLLLPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFFFL--------IPLGLIALLGALLL 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 662 LILADI-HDFEIILHRVEWATLLFFAALFVLME-------------------------IPVLLNL---------SHDPEV 706
Cdd:cd00625 241 LLLLVRgLDPEEVLKSVDWGTLLFFAGLFVLVGalestgllewlaellvalvglpplaALLLIGLlsallsnfiSNVPTV 320
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462544404 707 GL---------PAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMVVSCTVGMCYL 773
Cdd:cd00625 321 ALllpiaaslaPPEPAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
342-694 |
1.96e-51 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 182.90 E-value: 1.96e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 342 YALIIFEIVHRTLAAMLGSLAALAALAVigdrpSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGR 421
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVL-----TPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 422 VWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNqelrkM 501
Cdd:pfam03600 76 PRRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASA-----L 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 502 GLDFAGFTAHMFIGICLVLLV-CFPLLRLLYWNRKLYNKEPSEIVELKheihvwrltaqrispasreetavrrlllgkvl 580
Cdd:pfam03600 151 GLSFGDFGFFMFPPVGVALLLvGLLPLLLIFRKLLPVRKEEEAELEEL-------------------------------- 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 581 alehllarrlhtfhrqisqedknwetniqelqKKHRISDGILLAKCLTVLGFVIFMFFLNSfvpgihldlgwIAILGAIW 660
Cdd:pfam03600 199 --------------------------------RKRAIKDKLLLAISALVLALVILGFLLLS-----------VLALAGAL 235
|
330 340 350
....*....|....*....|....*....|....
gi 2462544404 661 LLILADIHDFEIILHRVEWATLLFFAALFVLMEI 694
Cdd:pfam03600 236 LLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGA 269
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
374-775 |
9.52e-40 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 151.28 E-value: 9.52e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 374 PSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGrVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVT 453
Cdd:cd01117 30 ISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGS-PRRLLFLLVLLSGILSALLTNDTACLVFTPIV 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 454 IRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSnqelrKMGLDFAGFTAHMF----IGICLVLLVCFpllrl 529
Cdd:cd01117 109 LELARVAGLPPIPLLLALATAANIGSAATPIGNPQNLLIAS-----ESGISFPFFLAAMAplalLGLLLLLILLL----- 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 530 LYWNRKLYNKEPSEIVELKHEIHVWRltaqrispasreetAVRRLLLgkvlalehllarrlhtfhrqisqedknwetniq 609
Cdd:cd01117 179 VLFPGELKGLPLDKATKEEGVGARKL--------------AVKLLVL--------------------------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 610 elqkkhrisdgillakCLTVLGFVIFMFFLNSFvpgihldlgWIAILGAIWLLILADIHDFEIILhRVEWATLLFFAALF 689
Cdd:cd01117 212 ----------------ILLLLVAFLALLGVIPL---------WTAALVAAVLLLLTRLKPRRVLK-KVDWGLLLFFAGLF 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 690 VLME-------------------------------------IPVLLNLShdPEVGLPAPPLMYALAFGACLGGNGTLIGA 732
Cdd:cd01117 266 ILVGgfaqglpleglsrllplldsvlslflvsiglsqlisnVPAVLLLL--PFLPSADEKDWLLLAAGSTIAGNLTLLGS 343
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 2462544404 733 SANVVCAGIAEQHGYGFSFMEFFRLGFPMMVVscTVGMCYLLV 775
Cdd:cd01117 344 AANLIVAEAAERRGVRLSFGEFLKYGVPLTLL--TAAIGILWL 384
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
392-770 |
1.74e-21 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 97.15 E-value: 1.74e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 392 FGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLD-----PRQ 466
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEkrskfGSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 467 VLIAEVIFTNIGGAATAIGDPPNVIIVSN-QELRKMGLDFAGFTAHMF-IGICLVLLVCFPLLRLLywnrklynkePSEI 544
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAGLlEEATGIPISFFEWMLVGLpVALVGLLLLWLVLYRLL----------PPEI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 545 VELKHEIHVWRLTAQRISPASREETAVrrlllgkvlalehllarrlhtfhrqisqedknwetniqelqkkhrisdgilla 624
Cdd:COG0471 151 KEVPGSKEVIREELAELGPLSRREKIA----------------------------------------------------- 177
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 625 kcLTVLGFVIFMFFLNSFvpgIHLDLGWIAILGAIwLLILADIHDFEIILHRVEWATLLFFAALF--------------- 689
Cdd:COG0471 178 --LAIFALTVLLWITGSL---HGIPIAVVALLGAV-LLLLTGVLTWKDAYKSIPWGVLLLFGGGLalgaalektglaawl 251
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 690 -------------------------VLMEI-----------PVLLNLSHdpEVGLPAPPLMYALAFGAcLGGNGTLIGAS 733
Cdd:COG0471 252 adallpllgglsplllllllalltlLLTEFasntataalllPIAISLAQ--ALGVNPLPLALAVAFAA-SCAFLLPVGTP 328
|
410 420 430
....*....|....*....|....*....|....*..
gi 2462544404 734 ANVVCAGIAeqhgyGFSFMEFFRLGFPMMVVSCTVGM 770
Cdd:COG0471 329 PNAIVYGSG-----YYKFKDFLKVGLPLNLIGLVVLL 360
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
383-770 |
3.05e-17 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 85.43 E-value: 3.05e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 383 IDFETLALLFGMMILVAIFSETGFFDYCA-VKAYRLSRGRvwAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLN 461
Cdd:PLN00136 61 IDLPILGLLFATMVVGSYLKNAGMFKHLGrLLAWRSQGGR--DLLCRVCVVTALASALFTNDTCCVVLTEFVLELAAERN 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 462 LDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLdFAGFTAHMFIG--ICLVLLVCfpllrlLYWNRKLYNK 539
Cdd:PLN00136 139 LPAKPFLLALASSANIGSSATPIGNPQNLVIAFNSKITFPKF-LLGILPAMLAGmaVNMVMLLC------MYWKDLDGGA 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 540 EPSEIVELKHEIHVWRLTAQRIS-PASREETAVRRLLLGKVLALEHLLARRLHTFHRqisqedknWETNIQELQKKHRIS 618
Cdd:PLN00136 212 ELSVDGKQMEAVEEGRSPASAKStKQQSPALLQAGLNGDGNGDMSSMMSENISTKHP--------WFMQCTEHRRKLFLK 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 619 DgilLAKCLTVLGFVIFMFFLNsfvpgihldLGWIAILGAIwLLILADIHDFEIILHRVEWATLLFFAALFV-------- 690
Cdd:PLN00136 284 S---FAYVVTVGMVVAYMVGLN---------MSWTAITTAI-ALVVVDFRDAEPCLDTVSYSLLVFFSGMFItvsgfnkt 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 691 -----------------------LMEIPVLL--NL-SHDPEVGLPAPPLMYA---------------LAFGACLGGNGTL 729
Cdd:PLN00136 351 glpgaiwnfmapyskvnsvggisVLSVIILLlsNLaSNVPTVLLMGDEVAAAaalispaavtrswllLAWVSTVAGNLSL 430
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 2462544404 730 IGASAN-VVC--AGIAEQHGYGFSFMEFFRLGFPMMVVSCTVGM 770
Cdd:PLN00136 431 LGSAANlIVCeqARRAPRNAYDLTFWQHIVFGVPSTLIVTAIGI 474
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
390-776 |
4.31e-15 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 78.01 E-value: 4.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 390 LLFGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLI 469
Cdd:cd01115 51 LFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLM 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 470 AEVIFTNIGGAATAIGDPPNVIIVSnqELRKMGLDFAGFTAHMFIGIcLVLLVCFPLLRLLYwnrklynKEPSEIVelkh 549
Cdd:cd01115 131 PLAFAASIGGMLTLIGTPPNLVASG--YLESLGGQGFSFFEFTPIGL-PLLIIGLLYLWFIF-------RLAVLII---- 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 550 EIHVWRLTAQRISPASREETAVrrlllgkVLALEHLLARRLHTfhRQIsQEDKNWETNIQelqkkhrISDGILLAKCL-- 627
Cdd:cd01115 197 TIVLLAALAAITGLLPVSVAIA-------IGAIVLVFGGVLLT--KED-YKSIDWGIIFL-------FAGGIPLGKALes 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 628 -----TVLGFVIFMFflnsfvpgihLDLGWIAILGAIWLLILAdIHDFeiILHrvewatllffAALFVLMeIPVLLNLSh 702
Cdd:cd01115 260 sgaaaLIAEALISLL----------GGLPPFAILLLLCLLTLV-LTNF--ISN----------TATAVLL-APIALSIA- 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462544404 703 dPEVGLPAPPLMYALAFGACLgGNGTLIGASANVVCAGiaeqhGYGFSFMEFFRLGFPMMVVSCTVGMCYLLVA 776
Cdd:cd01115 315 -LSLGLPPEALLLAVAIGASC-AFMLPVGTPPNAIVLG-----PGGYKFSDFAKVGLPLSILSLVVSVTMIPLI 381
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
391-763 |
5.35e-14 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 74.61 E-value: 5.35e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 391 LFGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIA 470
Cdd:cd01118 58 LIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPF 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 471 EVIFTNIGGAATA---IGDPPNVIIVSNqelrkMGLDFAGFTAHMFIGICLVLLVCFPLLRLLY-------WNRKLYNKE 540
Cdd:cd01118 138 LYACAFIADAASLplpISNLVNIVTAGY-----FGIGFTEYAALMFLPSIVSILATYVVLYLFFrralpkrLETASVKKP 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 541 PSEIVELKHEIHVWRLTA-QRISPASREETAVRRLLLGKVLALEHLLARRLHTFhrqisqedknweTNIQELQKKhrISD 619
Cdd:cd01118 213 SLAIKDPLLFGLAWTLLVlLVVSAFGVDILLIPPSFIAGVLALIFLLLARRGGA------------INPLKVLKE--APW 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 620 GILLakcltvlgFVIFMFFLnsfVPGIHlDLGWIAILGAiWLLILADIHDFEIIlhrveWATLLFFAALFVLM-EIPVLL 698
Cdd:cd01118 279 GVLL--------FSLGLYVV---VFGLK-NAGLTAILAD-LLNWLVSQGLLAAI-----LGVGLLAAFLSNVMnNLPAVL 340
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462544404 699 nlshdpeVGLPA-------PPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMV 763
Cdd:cd01118 341 -------IGALAlaaghapEALVYANLIGVDLGPKLTPIGSLATLLWLHVLRRKGIRVSWGYYLKVGLIVTP 405
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
376-529 |
2.58e-11 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 65.95 E-value: 2.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 376 LTHVVEW------IDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRG-RVWAMIIMLCLIAAVLSAFLDNVTTMLL 448
Cdd:COG0471 211 LTGVLTWkdayksIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPLLGGlSPLLLLLLLALLTLLLTEFASNTATAAL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 449 FTPVTIRLCEVLNLDPRQVLIAeVIFTNIGGAATAIGDPPNVII-----VSNQELRKMGLDFagftahMFIGICLVLLVC 523
Cdd:COG0471 291 LLPIAISLAQALGVNPLPLALA-VAFAASCAFLLPVGTPPNAIVygsgyYKFKDFLKVGLPL------NLIGLVVLLLLG 363
|
....*.
gi 2462544404 524 FPLLRL 529
Cdd:COG0471 364 PLWWPL 369
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
690-774 |
8.38e-10 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 61.32 E-value: 8.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 690 VLMEIPVLLNLSH---DPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAE-QHGYGFSFMEFFRLGFPMMVVS 765
Cdd:COG0471 55 AAMMLPIALSIAAalgSEKRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEeATGIPISFFEWMLVGLPVALVG 134
|
....*....
gi 2462544404 766 CTVGMCYLL 774
Cdd:COG0471 135 LLLLWLVLY 143
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
333-469 |
5.82e-08 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 55.40 E-value: 5.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 333 IATAILAGVYALIIFEIVhrtlaAMLGSLAALAALAVIGDRPSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAV 412
Cdd:pfam03600 207 LLLAISALVLALVILGFL-----LLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALAD 281
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2462544404 413 KAYRLSrgRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLI 469
Cdd:pfam03600 282 ALGGLS--GLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLA 336
|
|
| PRK15445 |
PRK15445 |
arsenical efflux pump membrane protein ArsB; |
370-468 |
7.83e-07 |
|
arsenical efflux pump membrane protein ArsB;
Pssm-ID: 185342 Cd Length: 427 Bit Score: 52.10 E-value: 7.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 370 IGDRPSLTHVVeWidFETLALLfGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLF 449
Cdd:PRK15445 42 LGDVPVVWGIV-W--NATLTFI-AIIIISLLLDEAGFFEWAALHVARWAKGNGRKLFVYIVLLGAAVAALFANDGAALIL 117
|
90
....*....|....*....
gi 2462544404 450 TPVTIRLCEVLNLDPRQVL 468
Cdd:PRK15445 118 TPIVLAMLLALGFSKKATL 136
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
383-531 |
7.93e-07 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 52.20 E-value: 7.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 383 IDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRG-RVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLN 461
Cdd:cd01115 239 IDWGIIFLFAGGIPLGKALESSGAAALIAEALISLLGGlPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLG 318
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462544404 462 LDPRQVLIAEVIftnIGGAA--TAIGDPPNVIIVSNQELRKMglDFagFTAHMFIGIcLVLLVCFPLLRLLY 531
Cdd:cd01115 319 LPPEALLLAVAI---GASCAfmLPVGTPPNAIVLGPGGYKFS--DF--AKVGLPLSI-LSLVVSVTMIPLIW 382
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
690-776 |
1.28e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 48.08 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 690 VLMEIPVLLNLSHdpEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMVvsctVG 769
Cdd:pfam03600 100 VLIMIPIVLALAR--RLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLL----VG 173
|
....*..
gi 2462544404 770 MCYLLVA 776
Cdd:pfam03600 174 LLPLLLI 180
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
648-774 |
1.78e-05 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 48.01 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 648 LDLGWIAILGAIWLLILADIHDFEIiLHRVEWATLLFFAALFVL------------------------------------ 691
Cdd:cd00625 9 LPRAVVALLGAVLLVLLGVVSPKEA-LSAIDWETILLLFGMMILsaaleetglfdrlaaklaraskgsrrlllllmllta 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 692 -------------MEIPVLLNLSHdPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAeqhgyGFSFMEFFRLG 758
Cdd:cd00625 88 alsaffsndatavLLTPIVLALLR-KLGLSPPVPLLLALAFAANIGGAATPIGNPPNLIIASLS-----GLGFLDFLAFM 161
|
170
....*....|....*...
gi 2462544404 759 FPMMVVS--CTVGMCYLL 774
Cdd:cd00625 162 APPALGLllLLLGLLYLL 179
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
376-527 |
4.12e-05 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 46.95 E-value: 4.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 376 LTHVVEW-------IDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIM--LCLIAAVLSAFLDNVTTM 446
Cdd:TIGR00785 285 FLGIVTWkdiqknkVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLvlVVLFYIILYFFASNTAHT 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 447 LLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVII-----VSNQELRKMGLDFAgftahmFIGICLVLL 521
Cdd:TIGR00785 365 AALVPIFFSVASAQGIPLELLALALALSASLMGFLTPYATPPNAIAygsgyVKIKDMWRVGAIIG------IVGLIVLLL 438
|
....*.
gi 2462544404 522 VCFPLL 527
Cdd:TIGR00785 439 VGTLWW 444
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
690-765 |
2.79e-03 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 40.79 E-value: 2.79e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462544404 690 VLMEIPVLLNLSHDPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGI-AEQHGYGFSFMEFFRLGFPMMVVS 765
Cdd:TIGR00785 132 IIKSLLPLLGSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGIlSKILGIQISWGDWFLAGLPLGIIL 208
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
376-492 |
3.08e-03 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 40.82 E-value: 3.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462544404 376 LTHVVEWID-------FETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAM--IIMLCLIAAVLSAFLDNVTTM 446
Cdd:pfam00939 306 LLRILDWKDivknkgaWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSLSGFSPAMafIIILSLFYLSHYLFASATAHT 385
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2462544404 447 LLFTPVTIRLCEVLNLDPRQVLIAEVIF-TNIGGAATAIGDPPNVII 492
Cdd:pfam00939 386 AAMLPIFAAVAQAIPGAPPLLAALLLGFaISLGGFLTPYGTGPGPIY 432
|
|
| |
