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Conserved domains on  [gi|2462547552|ref|XP_054235588|]
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transmembrane protein 170A isoform X6 [Homo sapiens]

Protein Classification

Tmemb_170 domain-containing protein( domain architecture ID 10562846)

Tmemb_170 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tmemb_170 super family cl10884
Putative transmembrane protein 170; Tmem170 is a family of putative transmembrane proteins ...
 7-83 2.49e-22

Putative transmembrane protein 170; Tmem170 is a family of putative transmembrane proteins conserved from fungi to nematodes to humans. The protein is only of approximately 130 amino acids in length. The function is unknown.


The actual alignment was detected with superfamily member pfam10190:

Pssm-ID: 462988  Cd Length: 106  Bit Score: 82.67  E-value: 2.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547552   7 EMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYG-----------------------AAIAGVYRAAGKEMIPFEALTL 63
Cdd:pfam10190   7 EMWYAIFLWALFSSIFVHLVAALIAFFTLRKHKFGrfipilillmgilipltggaitsAAIAFVYRASSFSMSPLYAMIW 86

                          90       100
                  ....*....|....*....|
gi 2462547552  64 GTGQTFCVLVVSFLRILATL 83
Cdd:pfam10190  87 GVGQTILLVIISFTRILATL 106
 
Name Accession Description Interval E-value
Tmemb_170 pfam10190
Putative transmembrane protein 170; Tmem170 is a family of putative transmembrane proteins ...
 7-83 2.49e-22

Putative transmembrane protein 170; Tmem170 is a family of putative transmembrane proteins conserved from fungi to nematodes to humans. The protein is only of approximately 130 amino acids in length. The function is unknown.


Pssm-ID: 462988  Cd Length: 106  Bit Score: 82.67  E-value: 2.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547552   7 EMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYG-----------------------AAIAGVYRAAGKEMIPFEALTL 63
Cdd:pfam10190   7 EMWYAIFLWALFSSIFVHLVAALIAFFTLRKHKFGrfipilillmgilipltggaitsAAIAFVYRASSFSMSPLYAMIW 86

                          90       100
                  ....*....|....*....|
gi 2462547552  64 GTGQTFCVLVVSFLRILATL 83
Cdd:pfam10190  87 GVGQTILLVIISFTRILATL 106
 
Name Accession Description Interval E-value
Tmemb_170 pfam10190
Putative transmembrane protein 170; Tmem170 is a family of putative transmembrane proteins ...
 7-83 2.49e-22

Putative transmembrane protein 170; Tmem170 is a family of putative transmembrane proteins conserved from fungi to nematodes to humans. The protein is only of approximately 130 amino acids in length. The function is unknown.


Pssm-ID: 462988  Cd Length: 106  Bit Score: 82.67  E-value: 2.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547552   7 EMWYGVFLWALVSSLFFHVPAGLLALFTLRHHKYG-----------------------AAIAGVYRAAGKEMIPFEALTL 63
Cdd:pfam10190   7 EMWYAIFLWALFSSIFVHLVAALIAFFTLRKHKFGrfipilillmgilipltggaitsAAIAFVYRASSFSMSPLYAMIW 86

                          90       100
                  ....*....|....*....|
gi 2462547552  64 GTGQTFCVLVVSFLRILATL 83
Cdd:pfam10190  87 GVGQTILLVIISFTRILATL 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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