NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2462547718|ref|XP_054235668|]
View 

cytochrome b-245 light chain isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Cytochrom_B558a super family cl04901
Cytochrome Cytochrome b558 alpha-subunit; Cytochrome b-245 light chain (p22-phox) is one of ...
2-126 5.24e-83

Cytochrome Cytochrome b558 alpha-subunit; Cytochrome b-245 light chain (p22-phox) is one of the key electron transfer elements of the NADPH oxidase in phagocytes.


The actual alignment was detected with superfamily member pfam05038:

Pssm-ID: 461532  Cd Length: 184  Bit Score: 244.34  E-value: 5.24e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547718   2 GQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKHMTAVVKLFG 81
Cdd:pfam05038   1 GQIEWAMWANEQALASGLILLAGGIVGVAGQFKGWEFAAYAIAAGVFICLLEYPRGKRKKGTTMERCGQKYMTAVVKVFG 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2462547718  82 PFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLSQV 126
Cdd:pfam05038  81 PLTRNYYVRAVLHAALAVPGGFLLATVLGTVCLGIASLIYLLAAI 125
 
Name Accession Description Interval E-value
Cytochrom_B558a pfam05038
Cytochrome Cytochrome b558 alpha-subunit; Cytochrome b-245 light chain (p22-phox) is one of ...
2-126 5.24e-83

Cytochrome Cytochrome b558 alpha-subunit; Cytochrome b-245 light chain (p22-phox) is one of the key electron transfer elements of the NADPH oxidase in phagocytes.


Pssm-ID: 461532  Cd Length: 184  Bit Score: 244.34  E-value: 5.24e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547718   2 GQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKHMTAVVKLFG 81
Cdd:pfam05038   1 GQIEWAMWANEQALASGLILLAGGIVGVAGQFKGWEFAAYAIAAGVFICLLEYPRGKRKKGTTMERCGQKYMTAVVKVFG 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2462547718  82 PFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLSQV 126
Cdd:pfam05038  81 PLTRNYYVRAVLHAALAVPGGFLLATVLGTVCLGIASLIYLLAAI 125
 
Name Accession Description Interval E-value
Cytochrom_B558a pfam05038
Cytochrome Cytochrome b558 alpha-subunit; Cytochrome b-245 light chain (p22-phox) is one of ...
2-126 5.24e-83

Cytochrome Cytochrome b558 alpha-subunit; Cytochrome b-245 light chain (p22-phox) is one of the key electron transfer elements of the NADPH oxidase in phagocytes.


Pssm-ID: 461532  Cd Length: 184  Bit Score: 244.34  E-value: 5.24e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462547718   2 GQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKHMTAVVKLFG 81
Cdd:pfam05038   1 GQIEWAMWANEQALASGLILLAGGIVGVAGQFKGWEFAAYAIAAGVFICLLEYPRGKRKKGTTMERCGQKYMTAVVKVFG 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2462547718  82 PFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLSQV 126
Cdd:pfam05038  81 PLTRNYYVRAVLHAALAVPGGFLLATVLGTVCLGIASLIYLLAAI 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH