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Conserved domains on  [gi|2508852219|ref|XP_056148443|]
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kinesin light chain 1-like isoform X3 [Lampris incognitus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
208-442 6.01e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 106.63  E-value: 6.01e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektl 287
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIy 367
Cdd:COG0457    72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2508852219 368 esrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRAHEKEFGSVDAENKPIWMHAEEREEMSKGKHRDN 442
Cdd:COG0457   140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 10-145 2.31e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219   10 EKLEKLSQEEiiSNTKLVIQGLEalKNEHNSILHSLLETIK-----CLKKDEEANLVHEKSNLLRKSVEMIELGLGEAQ- 83
Cdd:TIGR02168  213 ERYKELKAEL--RELELALLVLR--LEELREELEELQEELKeaeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQk 288

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2508852219   84 VMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLE 145
Cdd:TIGR02168  289 ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
208-442 6.01e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 106.63  E-value: 6.01e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektl 287
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIy 367
Cdd:COG0457    72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2508852219 368 esrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRAHEKEFGSVDAENKPIWMHAEEREEMSKGKHRDN 442
Cdd:COG0457   140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 224-495 8.17e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 93.44  E-value: 8.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 224 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI--REKTLGKDHPAVAATLNNL 301
Cdd:NF040586  405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGGL 484

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 302 AVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEveyyycrALEI----YESR---LGPD 374
Cdd:NF040586  485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYRE-------ALELdrevLRRRrrvLGPD 557

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 375 DPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRaHEKEFGSVDaenkpiwmhaeereemskgkhrdntpygeyggwyka 454
Cdd:NF040586  558 HPRTLLSANNLARDLRELGRYAEALDLLEEALER-YREVLGGPD------------------------------------ 600

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2508852219 455 ckvnSPTVNTTLRNLGALYRRQGKL-EAAETLEECATRSRKQ 495
Cdd:NF040586  601 ----HPDTLRAAKSLAVALRRAGRLeEALELAEDTYERYRRR 638
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 203-411 2.76e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 91.52  E-value: 2.76e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 203 GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNiLALVYRDQNKYKEAAHLLNDALS 281
Cdd:NF040586  597 GGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREVLD 675

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 282 IREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHP---DVAKQL-NNLALLCQNQGKYEEVE 357
Cdd:NF040586  676 RYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPytlAAAVNLaNDLAALGDLDAALGEEA 755

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2508852219 358 YYYCRALEIYESRLGPDDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRAHE 411
Cdd:NF040586  756 LERLRRLLGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLARLRR 809
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 210-491 1.44e-18

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 89.59  E-value: 1.44e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 210 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD--HPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREKTL 287
Cdd:NF040586  433 TLRLRFHLANALRSLGRYEEARELDEDTLERQRRVLGLGedHPHTLMTAGGLGADLRALGRFREALELDEETLERHRRVF 512

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIY 367
Cdd:NF040586  513 GEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERY 592

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 368 -ESRLGPDDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRaHEKEFGsvdaENKPIWM---------------HAEER 431
Cdd:NF040586  593 rEVLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYER-YRRRFG----PDHPDTLaaalslandlralgdADEAR 667

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 432 EEMSKGKHRDNTPYGEyggwykackvNSPTVNTTLRNLGALYRRQGKLEAAETLEECATR 491
Cdd:NF040586  668 ELAREVLDRYRRVLGE----------DHPFTLACRNNLAVLLRALGDPEEARELAEAALE 717
TPR_12 pfam13424
Tetratricopeptide repeat;
294-369 1.72e-17

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 77.04  E-value: 1.72e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508852219 294 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIYES 369
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 216-336 1.43e-10

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 64.17  E-value: 1.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 216 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHP-DVATMLN---ILALVYRDQNKYKEAAHLLNDALSIREKTLGKDH 291
Cdd:NF040586  694 NLAVLLRALGDPEEARELAEAALEGLRERLGPDHPyTLAAAVNlanDLAALGDLDAALGEEALERLRRLLGEDLRAGPDH 773

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2508852219 292 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDV 336
Cdd:NF040586  774 PDTLACAANLALDLRATGRTEEAEELRADTLARLRRVLGPDHPDT 818
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 209-403 1.84e-09

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 58.12  E-value: 1.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 209 ARLRTlhNLVIQYASQGRYEvavplckQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektlg 288
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLE-------VAKENLDKALEHD-PDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 289 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIye 368
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2508852219 369 srlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYK 403
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLE 193
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 10-145 2.31e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219   10 EKLEKLSQEEiiSNTKLVIQGLEalKNEHNSILHSLLETIK-----CLKKDEEANLVHEKSNLLRKSVEMIELGLGEAQ- 83
Cdd:TIGR02168  213 ERYKELKAEL--RELELALLVLR--LEELREELEELQEELKeaeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQk 288

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2508852219   84 VMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLE 145
Cdd:TIGR02168  289 ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 216-296 3.90e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 43.37  E-value: 3.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 216 NLVIQYASQGRYEVAvpLCKQALEDLE------KTSGHDHPDV-ATMLNiLALVYRDQNKYKEAAHLLNDALSIREKTLG 288
Cdd:NF040586  736 NLANDLAALGDLDAA--LGEEALERLRrllgedLRAGPDHPDTlACAAN-LALDLRATGRTEEAEELRADTLARLRRVLG 812


                  ....*...
gi 2508852219 289 KDHPAVAA 296
Cdd:NF040586  813 PDHPDTVA 820
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 264-414 8.50e-04

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 41.57  E-value: 8.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 264 RDQNKYKEAAHLLNDALSIREKT--LGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPdvAKQ-- 339
Cdd:cd24145   114 SELGKWELRERLLKKAVEILLKLgeLWMSPSEVGAFLEELATAYDLYGRFCLALPLYMQALSLKGQILLSQAN--CHSlv 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 340 -LNNLA----LLCQNQGKYEEVEYY------------------YCRALEIYESRLGPD-----DPNVAKTKNNLASCFLK 391
Cdd:cd24145   192 lMNNEAaelaLHALRKPLSSTLIEAsrlpqksrdqlleaalkwAQKALDVAKSIKPKDrdpecDQACALALYNLGVIAEM 271

                         170       180
                  ....*....|....*....|...
gi 2508852219 392 QGKYKEAEILYKEILTRAHEKEF 414
Cdd:cd24145   272 LGNLDEARKLYKEAISLAKELGF 294
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 295-327 1.13e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.13e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2508852219  295 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 327
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
208-442 6.01e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 106.63  E-value: 6.01e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektl 287
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIy 367
Cdd:COG0457    72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2508852219 368 esrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRAHEKEFGSVDAENKPIWMHAEEREEMSKGKHRDN 442
Cdd:COG0457   140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 224-495 8.17e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 93.44  E-value: 8.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 224 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSI--REKTLGKDHPAVAATLNNL 301
Cdd:NF040586  405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGGL 484

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 302 AVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEveyyycrALEI----YESR---LGPD 374
Cdd:NF040586  485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYRE-------ALELdrevLRRRrrvLGPD 557

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 375 DPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRaHEKEFGSVDaenkpiwmhaeereemskgkhrdntpygeyggwyka 454
Cdd:NF040586  558 HPRTLLSANNLARDLRELGRYAEALDLLEEALER-YREVLGGPD------------------------------------ 600

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2508852219 455 ckvnSPTVNTTLRNLGALYRRQGKL-EAAETLEECATRSRKQ 495
Cdd:NF040586  601 ----HPDTLRAAKSLAVALRRAGRLeEALELAEDTYERYRRR 638
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 179-409 2.10e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 91.98  E-value: 2.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 179 NDEEEHGQGMQHQHNSAAVAAAQQGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKtsGHDHPDVATMLNI 258
Cdd:COG3914     6 LLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAA--AAALLLLAALLEL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 259 LALVYRDQNKYKEAAHLLNDALSIrektlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAK 338
Cdd:COG3914    84 AALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDFAE 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2508852219 339 QLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRA 409
Cdd:COG3914   148 AYLNLGEALRRLGRLEEAIAALRRALEL--------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 203-411 2.76e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 91.52  E-value: 2.76e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 203 GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNiLALVYRDQNKYKEAAHLLNDALS 281
Cdd:NF040586  597 GGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREVLD 675

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 282 IREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHP---DVAKQL-NNLALLCQNQGKYEEVE 357
Cdd:NF040586  676 RYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPytlAAAVNLaNDLAALGDLDAALGEEA 755

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2508852219 358 YYYCRALEIYESRLGPDDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRAHE 411
Cdd:NF040586  756 LERLRRLLGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLARLRR 809
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 210-491 1.44e-18

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 89.59  E-value: 1.44e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 210 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD--HPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREKTL 287
Cdd:NF040586  433 TLRLRFHLANALRSLGRYEEARELDEDTLERQRRVLGLGedHPHTLMTAGGLGADLRALGRFREALELDEETLERHRRVF 512

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIY 367
Cdd:NF040586  513 GEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERY 592

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 368 -ESRLGPDDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRaHEKEFGsvdaENKPIWM---------------HAEER 431
Cdd:NF040586  593 rEVLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYER-YRRRFG----PDHPDTLaaalslandlralgdADEAR 667

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 432 EEMSKGKHRDNTPYGEyggwykackvNSPTVNTTLRNLGALYRRQGKLEAAETLEECATR 491
Cdd:NF040586  668 ELAREVLDRYRRVLGE----------DHPFTLACRNNLAVLLRALGDPEEARELAEAALE 717
TPR_12 pfam13424
Tetratricopeptide repeat;
294-369 1.72e-17

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 77.04  E-value: 1.72e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508852219 294 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIYES 369
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
208-406 4.08e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 4.08e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRektl 287
Cdd:COG0457    39 PDDAEALYNLGLAYLRLGRYEEALADYEQALEL--------DPDDAEALNNLGLALQALGRYEEALEDYDKALELD---- 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 gkdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIY 367
Cdd:COG0457   107 ----PDDAEALYNLGLALLELGRYDEAIEAYERALELD--------PDDADALYNLGIALEKLGRYEEALELLEKLEAAA 174

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2508852219 368 ESRLGPDDPNVAKTKNNLASCFLKQGKYKEAEILYKEIL 406
Cdd:COG0457   175 LAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAI 213
TPR_12 pfam13424
Tetratricopeptide repeat;
251-327 2.37e-16

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 73.96  E-value: 2.37e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2508852219 251 DVATMLNILALVYRDQNKYKEAAHLLNDALSIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 327
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 208-411 8.59e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.68  E-value: 8.59e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALsirektl 287
Cdd:COG2956    73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLE--------LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLL------- 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 gKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIy 367
Cdd:COG2956   138 -KLGPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCARALLLLAELYLEQGDYEEAIAALERALEQ- 207

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2508852219 368 esrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRAHE 411
Cdd:COG2956   208 -------DPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244
TPR_10 pfam13374
Tetratricopeptide repeat;
294-335 1.88e-13

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 64.45  E-value: 1.88e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2508852219 294 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPD 335
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
TPR_12 pfam13424
Tetratricopeptide repeat;
210-285 2.02e-13

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 65.49  E-value: 2.02e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508852219 210 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREK 285
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 221-485 2.00e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 2.00e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 221 YASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREKTlgkdhpavAATLNN 300
Cdd:COG2956    52 YRRRGEYDRAIRIHQKLLER--------DPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD--------AEALRL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 301 LAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdDPNVAK 380
Cdd:COG2956   116 LAEIYEQEGDWEKAIEVLERLLKL--------GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCAR 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 381 TKNNLASCFLKQGKYKEAEILYKEILtrAHEKEFGSVDAENKPIWMHAEEREEMSKgkhrdntpygeyggWYKACKVNSP 460
Cdd:COG2956   180 ALLLLAELYLEQGDYEEAIAALERAL--EQDPDYLPALPRLAELYEKLGDPEEALE--------------LLRKALELDP 243

                         250       260
                  ....*....|....*....|....*
gi 2508852219 461 TvNTTLRNLGALYRRQGKLEAAETL 485
Cdd:COG2956   244 S-DDLLLALADLLERKEGLEAALAL 267
TPR_12 pfam13424
Tetratricopeptide repeat;
335-409 4.00e-12

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 61.63  E-value: 4.00e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2508852219 335 DVAKQLNNLALLCQNQGKYEEVEYYYCRALEIYESRLGPDDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRA 409
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 209-367 7.38e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.90  E-value: 7.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 209 ARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektlg 288
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL------ 67

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2508852219 289 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvLGKDHPDVakqLNNLALLCQNQGKYEEVEYYYCRALEIY 367
Cdd:COG4783    68 --DPDEPEARLNLGLALLKAGDYDEALALLEKALK-----LDPEHPEA---YLRLARAYRALGRPDEAIAALEKALELD 136
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 220-411 1.27e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.33  E-value: 1.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 220 QYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRE-KTLGKDHPAVAATL 298
Cdd:COG3914     2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEaAAAAAALLLLAALL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 299 NNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdDPNV 378
Cdd:COG3914    82 ELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDF 145

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2508852219 379 AKTKNNLASCFLKQGKYKEAEILYKEILTRAHE 411
Cdd:COG3914   146 AEAYLNLGEALRRLGRLEEAIAALRRALELDPD 178
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 220-485 1.83e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 64.75  E-value: 1.83e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 220 QYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREKTlgkdhpavAATLN 299
Cdd:COG2956    17 NYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDR--------AEALL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 300 NLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEveyyycrALEIYEsRLGPDDPNVA 379
Cdd:COG2956    81 ELAQDYLKAGLLDRAEELLEKLLELD--------PDDAEALRLLAEIYEQEGDWEK-------AIEVLE-RLLKLGPENA 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 380 KTKNNLASCFLKQGKYKEAEILYKEILtrahekefgSVDAENKPIWMHAEEReEMSKGKhrdntpYGEYGGWYKACKVNS 459
Cdd:COG2956   145 HAYCELAELYLEQGDYDEAIEALEKAL---------KLDPDCARALLLLAEL-YLEQGD------YEEAIAALERALEQD 208

                         250       260
                  ....*....|....*....|....*.
gi 2508852219 460 PTVNTTLRNLGALYRRQGKLEAAETL 485
Cdd:COG2956   209 PDYLPALPRLAELYEKLGDPEEALEL 234
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 259-411 4.32e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.98  E-value: 4.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 259 LALVYRDQNKYKEAAHLLNDALsirektlgKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAK 338
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKAL--------ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL--------DPDEPE 73

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2508852219 339 QLNNLALLCQNQGKYEEVEYYYCRALEIYesrlgPDDPNVAktkNNLASCFLKQGKYKEAEILYKEILTRAHE 411
Cdd:COG4783    74 ARLNLGLALLKAGDYDEALALLEKALKLD-----PEHPEAY---LRLARAYRALGRPDEAIAALEKALELDPD 138
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 216-336 1.43e-10

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 64.17  E-value: 1.43e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 216 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHP-DVATMLN---ILALVYRDQNKYKEAAHLLNDALSIREKTLGKDH 291
Cdd:NF040586  694 NLAVLLRALGDPEEARELAEAALEGLRERLGPDHPyTLAAAVNlanDLAALGDLDAALGEEALERLRRLLGEDLRAGPDH 773

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2508852219 292 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDV 336
Cdd:NF040586  774 PDTLACAANLALDLRATGRTEEAEELRADTLARLRRVLGPDHPDT 818
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
262-371 5.70e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 56.33  E-value: 5.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 262 VYRDQNKYKEAAHLLNDALSIrektlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLcKRALEIrekvlgkdHPDVAKQLN 341
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63

                          90       100       110
                  ....*....|....*....|....*....|
gi 2508852219 342 NLALLCQNQGKYEEVEYYYCRALEIYESRL 371
Cdd:COG3063    64 NLAELLLELGDYDEALAYLERALELDPSAL 93
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
304-406 7.20e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.95  E-value: 7.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 304 LYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYcRALEIyesrlgpdDPNVAKTKN 383
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIALE-KALKL--------DPNNAEALL 63

                          90       100
                  ....*....|....*....|...
gi 2508852219 384 NLASCFLKQGKYKEAEILYKEIL 406
Cdd:COG3063    64 NLAELLLELGDYDEALAYLERAL 86
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
208-371 8.62e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 59.25  E-value: 8.62e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRektl 287
Cdd:COG0457    73 PDDAEALNNLGLALQALGRYEEALEDYDKALEL--------DPDDAEALYNLGLALLELGRYDEAIEAYERALELD---- 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 gkdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIY 367
Cdd:COG0457   141 ----PDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTL 216


                  ....
gi 2508852219 368 ESRL 371
Cdd:COG0457   217 AALA 220
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
216-403 1.23e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.39  E-value: 1.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 216 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRektlgkdhPAVA 295
Cdd:COG4785    36 ALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 296 ATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEveyyycrALEIYES--RLGP 373
Cdd:COG4785   108 EAYNNRGLAYLLLGDYDAALEDFDRALELD--------PDYAYAYLNRGIALYYLGRYEL-------AIADLEKalELDP 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2508852219 374 DDP-------------NVAKTKNNL----ASCFLKQGKYKEAEILYK 403
Cdd:COG4785   173 NDPeralwlylaerklDPEKALALLledwATAYLLQGDTEEARELFK 219
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 247-409 1.23e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 57.28  E-value: 1.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 247 HDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIre 326
Cdd:COG5010     6 GFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL-- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 327 kvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEIL 406
Cdd:COG5010    84 ------DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149


                  ...
gi 2508852219 407 TRA 409
Cdd:COG5010   150 GTS 152
TPR_10 pfam13374
Tetratricopeptide repeat;
252-292 1.81e-09

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 53.27  E-value: 1.81e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2508852219 252 VATMLNILALVYRDQNKYKEAAHLLNDALSIREKTLGKDHP 292
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHP 41
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 209-403 1.84e-09

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 58.12  E-value: 1.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 209 ARLRTlhNLVIQYASQGRYEvavplckQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektlg 288
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLE-------VAKENLDKALEHD-PDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 289 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIye 368
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2508852219 369 srlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYK 403
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLE 193
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 258-413 2.42e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.20  E-value: 2.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 258 ILALVYRDQNKYKEAAHLLNDALSIrektlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVA 337
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER--------DPDRA 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508852219 338 KQLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRAHEKE 413
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLEL--------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 208-366 5.01e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.35  E-value: 5.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektl 287
Cdd:COG5010     9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL----- 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2508852219 288 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEI 366
Cdd:COG5010    84 ---DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
221-329 8.83e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.87  E-value: 8.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 221 YASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLlNDALSIrektlgkdHPAVAATLNN 300
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALLN 64

                          90       100
                  ....*....|....*....|....*....
gi 2508852219 301 LAVLYGKRGKYKEAEPLCKRALEIREKVL 329
Cdd:COG3063    65 LAELLLELGDYDEALAYLERALELDPSAL 93
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 255-484 1.21e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 255 MLNILALVYRDQNKYKEAAHLLNDALSIREktlgkDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREkvLGKDHP 334
Cdd:COG3914     3 AAALLALAALAAAALLAAAAAAELALAAEL-----EAAALAAALGLALLLLAALAEAAAAALLALAAGEAAA--AAAALL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 335 DVAKQLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEILtrahekef 414
Cdd:COG3914    76 LLAALLELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRAL-------- 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2508852219 415 gSVDAENKPIWMH----AEEREEMSKGKHRdntpygeyggWYKACKVNsPTVNTTLRNLGALYRRQGKLEAAET 484
Cdd:COG3914   140 -ALNPDFAEAYLNlgeaLRRLGRLEEAIAA----------LRRALELD-PDNAEALNNLGNALQDLGRLEEAIA 201
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
259-432 5.79e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.38  E-value: 5.79e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 259 LALVYRDQNKYKEAAHLLNDALSIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAK 338
Cdd:COG4785    37 LAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLAE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 339 QLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdDPNVAKTKNNLASCFLKQGKYKEAEilykEILTRAHekEFGSVD 418
Cdd:COG4785   109 AYNNRGLAYLLLGDYDAALEDFDRALEL--------DPDYAYAYLNRGIALYYLGRYELAI----ADLEKAL--ELDPND 174

                         170
                  ....*....|....
gi 2508852219 419 AENkPIWMHAEERE 432
Cdd:COG4785   175 PER-ALWLYLAERK 187
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 236-386 1.17e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.77  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 236 QALEDLEKTSGHDHPDVATMLNiLALVYRDQNKYKEAAHLLNDALSIRektlgkdhPAVAATLNNLAVLYGKRGKYKEAE 315
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLL-LGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAE 71

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2508852219 316 PLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEiyesrLGPDDPNVAKTKNNLA 386
Cdd:COG4235    72 ELLERALAL--------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLA-----LLPADAPARLLEASIA 129
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 208-367 1.68e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.81  E-value: 1.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektl 287
Cdd:COG2956   141 PENAHAYCELAELYLEQGDYDEAIEALEKALK--------LDPDCARALLLLAELYLEQGDYEEAIAALERALEQ----- 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAkQLNNLALLCQNQGKYEEVEYYYCRALEIY 367
Cdd:COG2956   208 ---DPDYLPALPRLAELYEKLGDPEEALELLRKALEL--------DPSDD-LLLALADLLERKEGLEAALALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 293-409 2.59e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 2.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 293 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIYesrlg 372
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD----- 68

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2508852219 373 PDDPNVAktkNNLASCFLKQGKYKEAEILYKEILTRA 409
Cdd:COG4783    69 PDEPEAR---LNLGLALLKAGDYDEALALLEKALKLD 102
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 289-409 8.27e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.08  E-value: 8.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 289 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIye 368
Cdd:COG4235    11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL-- 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2508852219 369 srlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEILTRA 409
Cdd:COG4235    81 ------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 221-411 8.89e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 8.89e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 221 YASQGRYEVAVPLCKQALEdLEKTSGhdhpdvATMLniLALVYRDQNKYKEAAHLLNDALsirektlgKDHPAVAATLNN 300
Cdd:TIGR02917 713 YLRQKDYPAAIQAYRKALK-RAPSSQ------NAIK--LHRALLASGNTAEAVKTLEAWL--------KTHPNDAVLRTA 775

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 301 LAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQnQGKYEEVEYYYCRALEiyesrLGPDDPNVAK 380
Cdd:TIGR02917 776 LAELYLAQKDYDKAIKHYQTVVKK--------APDNAVVLNNLAWLYL-ELKDPRALEYAERALK-----LAPNIPAILD 841

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2508852219 381 TknnLASCFLKQGKYKEAEILYKEILTRAHE 411
Cdd:TIGR02917 842 T---LGWLLVEKGEADRALPLLRKAVNIAPE 869
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 307-408 1.41e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 47.29  E-value: 1.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 307 KRGKYKEAEPLCKRALEirekvLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIYesrlgPDDPNVAKTKNNLA 386
Cdd:COG1729     5 KAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY-----PDSPKAPDALLKLG 74

                          90       100
                  ....*....|....*....|..
gi 2508852219 387 SCFLKQGKYKEAEILYKEILTR 408
Cdd:COG1729    75 LSYLELGDYDKARATLEELIKK 96
TPR_10 pfam13374
Tetratricopeptide repeat;
211-251 1.59e-06

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 44.80  E-value: 1.59e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2508852219 211 LRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 251
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 248-407 2.94e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 2.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 248 DHPDVATMLNILALVYRDQNKYKEAAHLLNDALsirektlgKDHPAVAATLNNLAVLYGKRgKYKEAEPLCKRALEIRek 327
Cdd:TIGR02917 765 THPNDAVLRTALAELYLAQKDYDKAIKHYQTVV--------KKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLA-- 833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 328 vlgkdhPDVAKQLNNLALLCQNQGKYEeveyyycRALEIYE--SRLGPDDPNVaktKNNLASCFLKQGKYKEAEILYKEI 405
Cdd:TIGR02917 834 ------PNIPAILDTLGWLLVEKGEAD-------RALPLLRkaVNIAPEAAAI---RYHLALALLATGRKAEARKELDKL 897


                  ..
gi 2508852219 406 LT 407
Cdd:TIGR02917 898 LN 899
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
208-365 3.03e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 3.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRektl 287
Cdd:COG4785    70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALE--------LDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELD---- 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 288 gkdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK----------VLGKDHPDVAKQL--NNLALLCQNQGKYEE 355
Cdd:COG4785   138 ----PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNdperalwlylAERKLDPEKALALllEDWATAYLLQGDTEE 213

                         170
                  ....*....|
gi 2508852219 356 VEYYYCRALE 365
Cdd:COG4785   214 ARELFKLALA 223
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 235-409 7.12e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 7.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 235 KQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREKTLgkdhPAVAAtlnnLAVLYGKRGKYKEA 314
Cdd:TIGR02917 107 QQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSL----YAKLG----LAQLALAENRFDEA 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 315 EPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdDPNVAKTKNNLASCFLKQGK 394
Cdd:TIGR02917 179 RALIDEVLTA--------DPGNVDALLLKGDLLLSLGNIELALAAYRKAIAL--------RPNNIAVLLALATILIEAGE 242

                         170
                  ....*....|....*
gi 2508852219 395 YKEAEILYKEILTRA 409
Cdd:TIGR02917 243 FEEAEKHADALLKKA 257
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 208-324 8.53e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.38  E-value: 8.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLektsghdhPDVATMLNILALVYRDQNKYKEAAHLLNDALSIrektl 287
Cdd:COG4235    14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL----- 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2508852219 288 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 324
Cdd:COG4235    81 ---DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 208-324 1.22e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.18  E-value: 1.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALsirektl 287
Cdd:COG4783    35 PDNPEAFALLGEILLQLGDLDEAIVLLHEALE--------LDPDEPEARLNLGLALLKAGDYDEALALLEKAL------- 99

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2508852219 288 gKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 324
Cdd:COG4783   100 -KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 259-324 5.35e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 41.17  E-value: 5.35e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2508852219 259 LALVYRDQNKYKEAAHLLNDALsirekTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 324
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAAL-----ARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRA 63
TPR_10 pfam13374
Tetratricopeptide repeat;
336-377 6.65e-05

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 40.18  E-value: 6.65e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2508852219 336 VAKQLNNLALLCQNQGKYEEVEYYYCRALEIYESRLGPDDPN 377
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
TPR_12 pfam13424
Tetratricopeptide repeat;
378-495 1.79e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.06  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 378 VAKTKNNLASCFLKQGKYKEAEILYKEILTRAHEKEfgsvdaenkpiwmhaeereemskGKHRDNTPygeyggwykackv 457
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLL-----------------------GPDHPLTA------------- 45

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2508852219 458 nsptvnTTLRNLGALYRRQGKLEAAETLEECATRSRKQ 495
Cdd:pfam13424  46 ------TTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_1 pfam00515
Tetratricopeptide repeat;
295-327 2.16e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 2.16e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2508852219 295 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 327
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 10-145 2.31e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.28  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219   10 EKLEKLSQEEiiSNTKLVIQGLEalKNEHNSILHSLLETIK-----CLKKDEEANLVHEKSNLLRKSVEMIELGLGEAQ- 83
Cdd:TIGR02168  213 ERYKELKAEL--RELELALLVLR--LEELREELEELQEELKeaeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQk 288

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2508852219   84 VMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLE 145
Cdd:TIGR02168  289 ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
TPR_7 pfam13176
Tetratricopeptide repeat;
297-332 3.76e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 37.90  E-value: 3.76e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2508852219 297 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKD 332
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 216-296 3.90e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 43.37  E-value: 3.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 216 NLVIQYASQGRYEVAvpLCKQALEDLE------KTSGHDHPDV-ATMLNiLALVYRDQNKYKEAAHLLNDALSIREKTLG 288
Cdd:NF040586  736 NLANDLAALGDLDAA--LGEEALERLRrllgedLRAGPDHPDTlACAAN-LALDLRATGRTEEAEELRADTLARLRRVLG 812


                  ....*...
gi 2508852219 289 KDHPAVAA 296
Cdd:NF040586  813 PDHPDTVA 820
Mgr3-like cd24145
Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; ...
 264-414 8.50e-04

Mitochondrial inner membrane i-AAA protease supercomplex subunit Mgr3 and similar proteins; Mgr3 (also called mitochondrial genome-required protein 3) is a component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. The supercomplex is composed of Mgr1, Mgr3, and Yme1. Mgr3, together with Mgr1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation.


Pssm-ID: 467945 [Multi-domain]  Cd Length: 307  Bit Score: 41.57  E-value: 8.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 264 RDQNKYKEAAHLLNDALSIREKT--LGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPdvAKQ-- 339
Cdd:cd24145   114 SELGKWELRERLLKKAVEILLKLgeLWMSPSEVGAFLEELATAYDLYGRFCLALPLYMQALSLKGQILLSQAN--CHSlv 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 340 -LNNLA----LLCQNQGKYEEVEYY------------------YCRALEIYESRLGPD-----DPNVAKTKNNLASCFLK 391
Cdd:cd24145   192 lMNNEAaelaLHALRKPLSSTLIEAsrlpqksrdqlleaalkwAQKALDVAKSIKPKDrdpecDQACALALYNLGVIAEM 271

                         170       180
                  ....*....|....*....|...
gi 2508852219 392 QGKYKEAEILYKEILTRAHEKEF 414
Cdd:cd24145   272 LGNLDEARKLYKEAISLAKELGF 294
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 263-387 9.25e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 9.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 263 YRDQNKYKEAAHLLNDALSirektLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvLGKDHPDVAKQLNN 342
Cdd:COG1729     3 LLKAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLK-----RYPDSPKAPDALLK 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2508852219 343 LALLCQNQGKYEEVEYYYCRALEIYesrlgPDDPNVAKTKNNLAS 387
Cdd:COG1729    73 LGLSYLELGDYDKARATLEELIKKY-----PDSEAAKEARARLAR 112
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 295-327 1.13e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.13e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2508852219  295 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 327
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 221-280 1.33e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 37.32  E-value: 1.33e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 221 YASQGRYEVAVPLCKQALEdlektSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDAL 280
Cdd:pfam13432   7 ALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAAL 61
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 216-404 1.74e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 1.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 216 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDhPDVATMLNILALVYRDQNKykeaahlLNDALSIREKtLGKDHPAVA 295
Cdd:TIGR02917 395 ENAAARTQLGISKLSQGDPSEAIADLETAAQLD-PELGRADLLLILSYLRSGQ-------FDKALAAAKK-LEKKQPDNA 465

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 296 ATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIyesrlgpdD 375
Cdd:TIGR02917 466 SLHNLLGAIYLGKGDLAKAREAFEKALSI--------EPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTI--------D 529

                         170       180
                  ....*....|....*....|....*....
gi 2508852219 376 PNVAKTKNNLASCFLKQGKYKEAEILYKE 404
Cdd:TIGR02917 530 PKNLRAILALAGLYLRTGNEEEAVAWLEK 558
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
208-287 2.30e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 2.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 208 PARLRTLHNLVIQYASQGRYEVAVPLcKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREKTL 287
Cdd:COG3063    23 PDNADALNNLGLLLLEQGRYDEAIAL-EKALK--------LDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSAL 93
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 319-411 4.44e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 4.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 319 KRALEIREKVlgKDHPDVAKQLNNLALLCQNQGKYEEVEYYYCRALeiyesRLGPDDPNVaktKNNLASCFLKQGKYKEA 398
Cdd:COG4235     1 EAIARLRQAL--AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKAL-----RLDPDNADA---LLDLAEALLAAGDTEEA 70

                          90
                  ....*....|...
gi 2508852219 399 EILYKEILTRAHE 411
Cdd:COG4235    71 EELLERALALDPD 83
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
293-406 7.86e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.97  E-value: 7.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2508852219 293 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKD-----HPDVAKQLNNLALLCQNQGKYEEVEYYYCRALEIy 367
Cdd:COG4785    24 ILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIdralaLPDLAQLYYERGVAYDSLGDYDLAIADFDQALEL- 102

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2508852219 368 esrlgpdDPNVAKTKNNLASCFLKQGKYKEAEILYKEIL 406
Cdd:COG4785   103 -------DPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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