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Conserved domains on  [gi|517501792|ref|YP_008144496|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Liobagrus anguillicauda]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 2.74e-64

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 194.97  E-value: 2.74e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   1 MMYFLDLLLLSLVVGLIGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAALASEPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792  81 TWGAGSVKIYVFVYLIGVGAAALWFWGS-HGGYWVVVDEFKEFFVVRGDTSGVSLMYSVGGGMLVVCAWVLLLCLFVVLE 159
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGwYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 517501792 160 LTRGLSRGTLRAV 172
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 2.74e-64

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 194.97  E-value: 2.74e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   1 MMYFLDLLLLSLVVGLIGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAALASEPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792  81 TWGAGSVKIYVFVYLIGVGAAALWFWGS-HGGYWVVVDEFKEFFVVRGDTSGVSLMYSVGGGMLVVCAWVLLLCLFVVLE 159
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGwYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 517501792 160 LTRGLSRGTLRAV 172
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-115 1.76e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 36.71  E-value: 1.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   17 IGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAAL-ASEPFPETWGAGSVKIYVFVYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100
                  ....*....|....*....|
gi 517501792   96 IGVGAAALWFWGSHGGYWVV 115
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAA 100
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 2.74e-64

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 194.97  E-value: 2.74e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   1 MMYFLDLLLLSLVVGLIGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAALASEPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792  81 TWGAGSVKIYVFVYLIGVGAAALWFWGS-HGGYWVVVDEFKEFFVVRGDTSGVSLMYSVGGGMLVVCAWVLLLCLFVVLE 159
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGwYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 517501792 160 LTRGLSRGTLRAV 172
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 6.40e-38

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 127.66  E-value: 6.40e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   1 MMYFLDLLLLSLVVGLIGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAALASEPFPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792  81 TWGAGSVKIYVFVYLIGVGAAALWFWGSHGGYWVVVDEFKEFFVVRGDTSGVSLMYSVGGGMLVVCAWVLLLCLFVVLEL 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 517501792 161 TRGLSRGTLRAV 172
Cdd:MTH00065 161 TRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 6.65e-32

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 112.53  E-value: 6.65e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   1 MMYFLDLLLLSLVVGLIGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAALASEPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792  81 TWGAGSVKIYV--FVYLIGVGAAALWFWGSHGGYWVVVDEFKEFFVVRGDTSGVSLMYSVGGGMLVVCAWVLLLCLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVvgFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 517501792 159 ELTRGLSRGTLRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 1.46e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 88.12  E-value: 1.46e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   1 MMYFLDLLLLSLVVGLIGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAALASEPFPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792  81 TWGAGSVKIYVFVYLIGVG-AAALWFWGSHGGYWVVVDEFKEFFVvrgdtSGVSLMYSVGGGMLVVCAWVLLLCLFVVLE 159
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGfVGFYFYGGWEMLSWMGVDEANNLDL-----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 517501792 160 LTRGLSRGTLRAV 172
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-148 3.36e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 87.55  E-value: 3.36e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   1 MMYFLDLLLLSLVVGLIGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAALASEPFPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517501792  81 TWGAGSV-----------KIYVFVYLIGVGAAALWFWGSHGGYWVVVDEfKEFFVVRGDTSGVSLMYSVGGGMLVVCAW 148
Cdd:MTH00109  82 TWVSNKVvlgalllgllmELLLVLYVLKDDEVEVVFNFNGLGDWVIYDT-GGSGFFSEDAMGVAALYSYGTWLVVVTGW 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 25-171 1.36e-07

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 48.75  E-value: 1.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792  25 PYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAALASEPFPETWGAGSVKIYVFVYLIGVGAA-AL 103
Cdd:MTH00045  23 PYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGEVLVLSLLLSLWVFISfDN 102

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517501792 104 WFWGSHGGYWVVVDEfkeffvvrgDTSGVSLMYSVGGGMLVVCAWVLLLCLFVVLELTRGLSRGTLRA 171
Cdd:MTH00045 103 FLELSNNNWSLVSLS---------DLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-115 1.76e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 36.71  E-value: 1.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792   17 IGVASNPAPYFAALGLAMAAGVGCGVLIGHGGSLIGLMLFLIYLGGMLVVFAYSAAL-ASEPFPETWGAGSVKIYVFVYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100
                  ....*....|....*....|
gi 517501792   96 IGVGAAALWFWGSHGGYWVV 115
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAA 100
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 47-145 8.24e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 35.25  E-value: 8.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517501792  47 GGSLIGLMLFLIYLGGMLVVFAYSAALASEPFpetwgAGSVKIYVFVYLIGVGAAALWFWGSHGGYWVVVDEFKEFFVVR 126
Cdd:MTH00152  45 LSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPL-----FGSNFKFVFFSLTLFGFLGLFFFFLYLYSSGGLSLSSLFDGSS 119

                         90
                 ....*....|....*....
gi 517501792 127 GDTSGVSLMYSVGGGMLVV 145
Cdd:MTH00152 120 GSLSFGGGLYSSSGWSIFV 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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