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Conserved domains on  [gi|570700638|ref|YP_008994367|]
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ATP synthase F0 subunit 6 (mitochondrion) [Pampus echinogaster]

Protein Classification

FoF1 ATP synthase subunit a( domain architecture ID 116)

FoF1 ATP synthase subunit a is part of the membrane proton channel (Fo complex) of the F-type ATPase that produces ATP from ADP in the presence of a proton gradient across the membrane; it plays a direct role in the translocation of protons across the membrane

Gene Ontology:  GO:0045263|GO:0015078|GO:0015986
PubMed:  11533110|12370007|30901262

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP-synt_Fo_a_6 super family cl00413
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 1-226 2.17e-76

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


The actual alignment was detected with superfamily member MTH00132:

Pssm-ID: 469762  Cd Length: 227  Bit Score: 229.76  E-value: 2.17e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVLVPWVFIPNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638 161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQEN 226
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-226 2.17e-76

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 229.76  E-value: 2.17e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVLVPWVFIPNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638 161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQEN 226
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 3-226 1.36e-44

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 148.51  E-value: 1.36e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638    3 LSLFTQFSLMYIFIIPSSLVAVLVPWVFI--PNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:TIGR01131   2 FSQFDISPITLFSLTLLSLILLLSLLIFLisSSLSRWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:TIGR01131  82 LISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVR 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638  161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTavLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:TIGR01131 162 LFANISAGHLLLTLLSGLLFSLMSSAIFALLLL--ILVALIILEIFVAFIQAYVFTLLTCLYLNDA 225
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-224 1.19e-38

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 130.98  E-value: 1.19e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  66 GHVWTLMFVTLAAYLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIV 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 570700638 146 ESLSLIIRPLALGVRLAANITAGHLLVHLVAKVTFILLTTFeisVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQ 224
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSV---GLLPLLLPVALTLLELFVAFIQAYVFTLLTAVYIS 156
ATP-synt_A pfam00119
ATP synthase A chain;
65-224 7.92e-31

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 112.97  E-value: 7.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   65 EGHVWTLMFVTLAAYLVFLNLLGLV---PYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNS-DRFVAHLLPPGTPTFIIP 140
Cdd:pfam00119  53 KGRKFFPLLLTLFFFILVSNLLGLIpksPGGFTVTADINVTLALALIVFLLVHYYGIKKHGlGGYFKKLFVPPVPLPLVP 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  141 ILVIVESLSLIIRPLALGVRLAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLS 220
Cdd:pfam00119 133 LLLPIEIISEFARPVSLSLRLFGNMLAGHLLLLLLAGLIFALLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTA 212


                  ....
gi 570700638  221 LYLQ 224
Cdd:pfam00119 213 VYIS 216
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 65-225 7.07e-25

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 97.07  E-value: 7.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  65 EGHVWTLMFVTLAAYLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNS-DRFVAHLLPPGTPtFIIPILV 143
Cdd:COG0356   53 KGRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGlGGYLKHLFFPPFP-WLAPLML 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638 144 IVESLSLIIRPLALGVRLAANITAGHLLVHLvakvtFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYL 223
Cdd:COG0356  132 PIEIISELARPLSLSLRLFGNMFAGHIILLL-----LAGLAPFLLLGVLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYI 206


                 ..
gi 570700638 224 QE 225
Cdd:COG0356  207 SL 208
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-226 2.17e-76

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 229.76  E-value: 2.17e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVLVPWVFIPNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638 161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQEN 226
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-226 4.37e-74

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 224.08  E-value: 4.37e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVLVPWVFIPNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638 161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00073 161 LTANLTAGHLLIQLISTATLVLLPLMPTVSILTMIVLFLLTLLEIAVAMIQAYVFVLLLSLYLQEN 226
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-226 1.03e-71

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 217.77  E-value: 1.03e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVLVPWVFIPNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638 161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00120 161 LTANLTAGHLLIQLISTATLNLLPTMPTLSLLTLIILLLLTILELAVAMIQAYVFVLLLSLYLQEN 226
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-226 3.12e-64

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 199.02  E-value: 3.12e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVLVPWVFIPNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638 161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00179 161 LTANITAGHLLMHLISSAVFVLMNFMGMVALLTLLVLFLLTLLEVAVAMIQAYVFVLLLSLYLQEN 226
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-226 5.71e-58

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 182.84  E-value: 5.71e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVLVPWVFIPnSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:MTH00101   1 MNENLFASFITPTILGLPIVTLIIMFPSLLFP-TPNRLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:MTH00101  80 GSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVR 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638 161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00101 160 LTANITAGHLLIHLIGGATLALMSISTTTALITFIILILLTILEFAVALIQAYVFTLLVSLYLHDN 225
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 1-226 7.27e-46

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 152.05  E-value: 7.27e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVL--VPWVFIPNSSlQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAA 78
Cdd:MTH00035   3 INNSIFGQFSPDTILFIPLTLLSSViaLSWLFFINPT-NWLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  79 YLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALG 158
Cdd:MTH00035  82 LILSINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALG 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 570700638 159 VRLAANITAGHLLVHLVAKVTFILLTTFEISVVfTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00035 162 LRLAANLTAGHLLIFLLSTAIWELSNSPLISII-TLIIFFLLFILEIGVACIQAYVFTALVHFYLEQN 228
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 3-226 1.36e-44

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 148.51  E-value: 1.36e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638    3 LSLFTQFSLMYIFIIPSSLVAVLVPWVFI--PNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAAYL 80
Cdd:TIGR01131   2 FSQFDISPITLFSLTLLSLILLLSLLIFLisSSLSRWLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   81 VFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVR 160
Cdd:TIGR01131  82 LISNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVR 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638  161 LAANITAGHLLVHLVAKVTFILLTTFEISVVFTavLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:TIGR01131 162 LFANISAGHLLLTLLSGLLFSLMSSAIFALLLL--ILVALIILEIFVAFIQAYVFTLLTCLYLNDA 225
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-225 2.61e-44

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 147.62  E-value: 2.61e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLvavlvpWvFIPNSslqwdpdrsYSIRKWSMSMLIREIFSPTLLEGHV-WTLMFVTLAAY 79
Cdd:MTH00157  15 FNLSLNWLSTFLGLLFIPSSF------W-LIPSR---------YNILWNKILKTLHKEFKTLLGPKNKgSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  80 LVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGV 159
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 570700638 160 RLAANITAGHLLVHLVAKVTFILLTTFEISVVFTavlLTLLIILEVAVAVIQAYVFILLLSLYLQE 225
Cdd:MTH00157 159 RLAANMIAGHLLLTLLGNTGPSLSSMILSILILI---QILLLILESAVAIIQSYVFSVLSTLYSSE 221
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-226 4.82e-40

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 137.09  E-value: 4.82e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSSLVAVLVPWVF-IPNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHV-WTLMFVTLAA 78
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMISLSWITLLLFlLLMPSSVWFCPSKLQVFMLMFSTFLPEMILRSNGSYILgSASIIISLFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  79 YLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALG 158
Cdd:MTH00176  81 LVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTLA 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 570700638 159 VRLAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQEN 226
Cdd:MTH00176 161 VRLAANLSAGHLLLGLLGAAMWGLLPVSPLIGFLLLIVQILYFMFEIAVCMIQAYVFTLLLSLYLDEH 228
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-224 1.19e-38

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 130.98  E-value: 1.19e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  66 GHVWTLMFVTLAAYLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIV 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 570700638 146 ESLSLIIRPLALGVRLAANITAGHLLVHLVAKVTFILLTTFeisVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQ 224
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSV---GLLPLLLPVALTLLELFVAFIQAYVFTLLTAVYIS 156
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 9-225 5.03e-36

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 126.90  E-value: 5.03e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   9 FSLMYIFIIPSSLvavlvpWVFIPNSSLqwdpdrSYSIRKWSMSMLIREIFSPTLLEGhvwTLMFVTLAAYLVFLNLLGL 88
Cdd:MTH00173  26 LSLMSLFFFSSSV------WVSSSNLSS------VFKLFVLTVSSQVTRSSGLNLGGF---SLLLSSLFLFLISLNLSGL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  89 VPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALGVRLAANITAG 168
Cdd:MTH00173  91 LPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLTVRLLANISAG 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638 169 HLLVHLVAKVTFILLttFEISVVFTAVLLTLLI---ILEVAVAVIQAYVFILLLSLYLQE 225
Cdd:MTH00173 171 HIVLTLIGNYLSSSL--FSSSVVSLLLVLLIQVgyfIFEVAVMLIQAYIFTLLIKLYSDE 228
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 1-223 6.39e-31

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 113.60  E-value: 6.39e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   1 MNLSLFTQFSLMYIFIIPSS--LVAVLVPWVFIPNSSLQWDPDRSYSIRKWSMSMLIREIFSPTLLEGHVWTLMFVTLAA 78
Cdd:MTH00172   1 MSSSYFDQFNIVWLIGLTNSsiMMILVIIVVLLLFKGIKLIPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLFF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  79 YLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALG 158
Cdd:MTH00172  81 FIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYISRAISLG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 570700638 159 VRLAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYL 223
Cdd:MTH00172 161 VRLAANLSAGHLLFAILAGFGFNMLCASGFLSLFPLLIMVFITLLEIAVAVIQAYVFCLLTTIYL 225
ATP-synt_A pfam00119
ATP synthase A chain;
65-224 7.92e-31

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 112.97  E-value: 7.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638   65 EGHVWTLMFVTLAAYLVFLNLLGLV---PYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNS-DRFVAHLLPPGTPTFIIP 140
Cdd:pfam00119  53 KGRKFFPLLLTLFFFILVSNLLGLIpksPGGFTVTADINVTLALALIVFLLVHYYGIKKHGlGGYFKKLFVPPVPLPLVP 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  141 ILVIVESLSLIIRPLALGVRLAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLS 220
Cdd:pfam00119 133 LLLPIEIISEFARPVSLSLRLFGNMLAGHLLLLLLAGLIFALLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTA 212


                  ....
gi 570700638  221 LYLQ 224
Cdd:pfam00119 213 VYIS 216
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 72-222 1.11e-29

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 110.21  E-value: 1.11e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  72 MFVTLAAYLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLI 151
Cdd:MTH00005  76 LISALFTMIILMNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISIL 155

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 570700638 152 IRPLALGVRLAANITAGHLLVHLVAKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLY 222
Cdd:MTH00005 156 VRPITLSFRLAANMSAGHIVLSLIGIYAASALFSSISSTILLILTQMGYILFEVGICLIQAYIFCLLLSLY 226
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 74-223 6.88e-27

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 103.16  E-value: 6.88e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  74 VTLAAYLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIR 153
Cdd:MTH00175  87 LSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLVLIETLSYLIR 166

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 570700638 154 PLALGVRLAANITAGHLLVHLVAKVTF-ILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYL 223
Cdd:MTH00175 167 AISLGVRLAANISAGHLLFAILSGFAFnMLSNGLIILSLFPMLIMIFITLLEMAVAVIQAYVFCLLTTIYL 237
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 65-225 7.07e-25

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 97.07  E-value: 7.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  65 EGHVWTLMFVTLAAYLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNS-DRFVAHLLPPGTPtFIIPILV 143
Cdd:COG0356   53 KGRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGlGGYLKHLFFPPFP-WLAPLML 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638 144 IVESLSLIIRPLALGVRLAANITAGHLLVHLvakvtFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYL 223
Cdd:COG0356  132 PIEIISELARPLSLSLRLFGNMFAGHIILLL-----LAGLAPFLLLGVLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYI 206


                 ..
gi 570700638 224 QE 225
Cdd:COG0356  207 SL 208
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 65-225 5.04e-19

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 82.15  E-value: 5.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  65 EGHVWTLMFVTLAAYLVFLNLLGLVP-YTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNS-DRFVAHLLPPGTPtFIIPIl 142
Cdd:PRK05815  68 KGKKFAPLAFTLFLFILLMNLLGLIPyLLFPPTADINVTLALALIVFVLVIYYGIKKKGlGGYLKEFYLQPHP-LLLPI- 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638 143 vivESLSLIIRPLALGVRLAANITAGHLLVhlvaKVTFILLTTFEISVVFTAVLLTLLIILEVAVAVIQAYVFILLLSLY 222
Cdd:PRK05815 146 ---EIISEFSRPISLSLRLFGNMLAGELIL----ALIALLGGAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVY 218


                 ...
gi 570700638 223 LQE 225
Cdd:PRK05815 219 ISM 221
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 74-225 6.89e-18

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 79.60  E-value: 6.89e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  74 VTLAAYLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDRFVAHLLPPGTPTFIIPILVIVESLSLIIR 153
Cdd:MTH00174  95 LSLFILILFGNGLGLFPYVFTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFSILMPQGAPLALAPLLTIIETLSYISR 174

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 570700638 154 PLALGVRLAANITAGHLLVHLVAKVTFILLTTFEISVVFTA-VLLTLLIILEVAVAVIQAYVFILLLSLYLQE 225
Cdd:MTH00174 175 AISLGVRLAANISSGHLLFSIIASFAWKMINTGILIGSFVPfAILIFVTILEMAVAIIQAYVFTLLTIVYLRD 247
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 74-223 4.81e-17

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 78.25  E-value: 4.81e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  74 VTLAAYLVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSDR-FVAHLlPPGTPTFIIPILVIVESLSLII 152
Cdd:PRK13419 175 LTVFFFILVCNLLGLVPYGATATGNINVTLTLAVFTFFITQYAAIKAHGIKgYLAHL-TGGTHWSLWIIMIPIEFIGLFT 253

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 570700638 153 RPLALGVRLAANITAGHLLVHLVAKVTFILLTtfEISVVFTAVLLTLLI-ILEVAVAVIQAYVFILLLSLYL 223
Cdd:PRK13419 254 KPFALTVRLFANMTAGHIVILSLIFISFILKS--YIVAVAVSVPFAIFIyLLELFVAFLQAYIFTMLSALFI 323
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 80-225 1.06e-12

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 64.23  E-value: 1.06e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  80 LVFLNLLGLVPYTFSPTSHLSHNLAFAVPFWLVTTIVSIVKNSdrFVAHLLPPGTPTFIIP-ILVIVESLSLIIRPLALG 158
Cdd:MTH00087  62 LLLFCFGGLFPYSFSPCGMVEFTFLYALVAWLSTFLSFLSKSE--KFSVYLSKGSDSFLKTfSMLFVEIVSELSRPLALT 139

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 570700638 159 VRLAANITAGHLLVHLVAKVTFillttfeisvvFTAVLLTLLIILEVAVAVIQAYVFILLLSLYLQE 225
Cdd:MTH00087 140 LRLTVNLMVGHLISSLLNFLGE-----------KYVWLSILAIMMECFVAFIQSYIFSRLIYLYLNE 195
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 66-223 5.40e-08

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 52.20  E-value: 5.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  66 GHVWTLMFVTLAAYLVFLNLLGLVP---------------YTFSPTSHLSHNLAFAVPFWLVTTIV-------------- 116
Cdd:PRK13417 154 GHSYYHYIFTLFFFILFCNLMGLVPsvgeltvvasdygglVALGVMDHTPHALPTFAKVWSGITVTgdisvtmtlalltm 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638 117 ------SIVKNSDRFVAHLLPPGTPTFIIPILVIVESL-SLIIRPLALGVRLAANITAGHLLVhlVAKVTFILLTTFEIS 189
Cdd:PRK13417 234 fliygaGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEFIvSPMAKTFALTVRLLANMTAGHVII--LALMGFIFQFQSWGI 311

                        170       180       190
                 ....*....|....*....|....*....|....
gi 570700638 190 VVFTAVLLTLLIILEVAVAVIQAYVFILLLSLYL 223
Cdd:PRK13417 312 VPVSVIGSGLIYVLEIFVAFLQAYIFVLLTSLFV 345
ATP6 MTH00050
ATP synthase F0 subunit 6; Validated
 80-168 7.27e-03

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177125  Cd Length: 170  Bit Score: 36.02  E-value: 7.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 570700638  80 LVFLNLLGLVPYTFSPTSHLSHnLAFAVPFWLVTTIVSIVKNS-DRFVAHLLPPGTPTFIIPILVIVESLSLIIRPLALG 158
Cdd:MTH00050  33 VLFLFLLYRLPYIYSPFLFVVF-LFVVVFPLFISLFLSRVFDSlNEFFSSFVPVGTPLYICPFVCIAETISYIIRPVVLI 111

                         90
                 ....*....|
gi 570700638 159 VRLAANITAG 168
Cdd:MTH00050 112 LRPFINISLG 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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