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Conserved domains on  [gi|674840510|ref|YP_009054353|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Papilio polytes]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 2-90 1.04e-23

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 85.98  E-value: 1.04e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  2 MNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLMIFLLFSVCEGALGLSILVSMIR 81
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 674840510 82 THGNDYFQS 90
Cdd:MTH00162 81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 2-90 1.04e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 85.98  E-value: 1.04e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  2 MNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLMIFLLFSVCEGALGLSILVSMIR 81
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 674840510 82 THGNDYFQS 90
Cdd:MTH00162 81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
6-94 8.78e-05

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 37.93  E-value: 8.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510   6 LLIMMMFIFGNMIFISKhKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLMIFLL--FSVCEGALGLSILVSMIRTH 83
Cdd:pfam00420  4 LLSGLLFLIGLYGLLLR-RNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAivIAAAEAAVGLALLVRIYRTH 82

                         90
                 ....*....|.
gi 674840510  84 GNDYFQSFSML 94
Cdd:pfam00420 83 GTDDVDSLNLL 93
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 2-90 1.04e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 85.98  E-value: 1.04e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  2 MNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLMIFLLFSVCEGALGLSILVSMIR 81
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 674840510 82 THGNDYFQS 90
Cdd:MTH00162 81 SHGNDYFSS 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 1-94 7.26e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 61.01  E-value: 7.26e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  1 MMNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLMIFLLFSVCEGALGLSILVSMI 80
Cdd:MTH00149  2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                        90
                ....*....|....
gi 674840510 81 RTHGNDYFQSFSML 94
Cdd:MTH00149 82 RLHGNDYVSSLSSL 95
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 1-93 7.90e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 61.14  E-value: 7.90e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  1 MMNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLMIFLLFSVCEGALGLSILVSMI 80
Cdd:MTH00188  2 FFSMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLI 81

                        90
                ....*....|...
gi 674840510 81 RTHGNDYFQSFSM 93
Cdd:MTH00188 82 RSHGSDYVSSLNL 94
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-94 6.09e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 51.00  E-value: 6.09e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  1 MMNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLM--IFLLFSVCEGALGLSILVS 78
Cdd:MTH00125  1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVA 80

                        90
                ....*....|....*.
gi 674840510 79 MIRTHGNDYFQSFSML 94
Cdd:MTH00125 81 TTRTHGSDHLKNLNLL 96
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 12-94 2.41e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 49.58  E-value: 2.41e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510 12 FIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYML--MIFLLFSVCEGALGLSILVSMIRTHGNDYFQ 89
Cdd:MTH00126 12 FILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAapMLLLAFSACEASAGLALLVATARTHGTDRLQ 91


                ....*
gi 674840510 90 SFSML 94
Cdd:MTH00126 92 NLNLL 96
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 4-94 3.69e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 46.48  E-value: 3.69e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  4 MWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEY--DMYMLMIFLLFSVCEGALGLSILVSMIR 81
Cdd:MTH00181  1 MMFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSssMLMFGLILLTFSACEAVLGLSLLVATNR 80

                        90
                ....*....|...
gi 674840510 82 THGNDYFQSFSML 94
Cdd:MTH00181 81 THGSDHLLKFNLL 93
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-94 5.60e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 46.14  E-value: 5.60e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  1 MMNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYML--MIFLLFSVCEGALGLSILVS 78
Cdd:MTH00067  1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALMVA 80

                        90
                ....*....|....*.
gi 674840510 79 MIRTHGNDYFQSFSML 94
Cdd:MTH00067 81 TTRTHGTDHLKNLNLL 96
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 1-93 1.76e-05

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 39.73  E-value: 1.76e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  1 MMNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLS-CIEYDMYMLMIFLLFSVCEGALGLSILVSM 79
Cdd:MTH00013  1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMfANQVNGMLAIVLLTFGACEASLGLSLLVLM 80

                        90
                ....*....|....
gi 674840510 80 IRTHGNDYFQSFSM 93
Cdd:MTH00013 81 TRSYGNDMLKSLTS 94
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
6-94 8.78e-05

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 37.93  E-value: 8.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510   6 LLIMMMFIFGNMIFISKhKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLMIFLL--FSVCEGALGLSILVSMIRTH 83
Cdd:pfam00420  4 LLSGLLFLIGLYGLLLR-RNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAivIAAAEAAVGLALLVRIYRTH 82

                         90
                 ....*....|.
gi 674840510  84 GNDYFQSFSML 94
Cdd:pfam00420 83 GTDDVDSLNLL 93
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-94 1.04e-04

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 37.60  E-value: 1.04e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  1 MMNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYMLM--IFLLFSVCEGALGLSILVS 78
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMpiILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*.
gi 674840510 79 MIRTHGNDYFQSFSML 94
Cdd:MTH00107 81 VSNTYGTDYVQNLNLL 96
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-94 9.68e-04

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 35.28  E-value: 9.68e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 674840510  1 MMNMWLLIMMMFIFGNMIFISKHKHLLIVLLSLEFIVLSLFFLLVVYLSCIEYDMYML--MIFLLFSVCEGALGLSILVS 78
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSfsLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*.
gi 674840510 79 MIRTHGNDYFQSFSML 94
Cdd:MTH00043 81 LSRNHNSDLVASLNLL 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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