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Conserved domains on  [gi|813424642|ref|YP_009132309|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Penaeus penicillatus]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 6-93 2.23e-19

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 75.19  E-value: 2.23e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642  6 FYYIVPVVSVLCGLWVFVSKRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFVLFFLTLAACEGALGLALLVSVVRT 85
Cdd:MTH00162  2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                ....*...
gi 813424642 86 HGNDCFSS 93
Cdd:MTH00162 82 HGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 6-93 2.23e-19

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 75.19  E-value: 2.23e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642  6 FYYIVPVVSVLCGLWVFVSKRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFVLFFLTLAACEGALGLALLVSVVRT 85
Cdd:MTH00162  2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                ....*...
gi 813424642 86 HGNDCFSS 93
Cdd:MTH00162 82 HGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
6-99 5.73e-11

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 53.72  E-value: 5.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642   6 FYYIVPVVSVLCGLWVFVSkRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGH--ESYFVLFFLTLAACEGALGLALLVSVV 83
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADplPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 813424642  84 RTHGNDCFSSFSVLQC 99
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 4-88 1.70e-04

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 37.35  E-value: 1.70e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642  4 LNFYYIVPVVSVLCGLWVFVSkRKHLLNTLLSLEyIMLS----IFWIMSLHLSNMGHESyFVLFFLTLAACEGALGLALL 79
Cdd:COG0713   3 LEHYLILAAILFAIGLYGVLT-RRNLIVVLMSIE-LMLNavnlNLVAFSRYLGDLDGQV-FALFVIAVAAAEVAVGLAII 79


                ....*....
gi 813424642 80 VSVVRTHGN 88
Cdd:COG0713  80 VALYRNRGT 88
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 6-93 2.23e-19

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 75.19  E-value: 2.23e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642  6 FYYIVPVVSVLCGLWVFVSKRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFVLFFLTLAACEGALGLALLVSVVRT 85
Cdd:MTH00162  2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                ....*...
gi 813424642 86 HGNDCFSS 93
Cdd:MTH00162 82 HGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 9-99 1.58e-16

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 68.08  E-value: 1.58e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642  9 IVPVVSVLCGLWVFVSKRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFVLFFLTLAACEGALGLALLVSVVRTHGN 88
Cdd:MTH00188  7 LVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHGS 86

                        90
                ....*....|.
gi 813424642 89 DCFSSFSVLQC 99
Cdd:MTH00188 87 DYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 26-99 2.89e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 62.56  E-value: 2.89e-14
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 813424642 26 RKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFVL--FFLTLAACEGALGLALLVSVVRTHGNDCFSSFSVLQC 99
Cdd:MTH00125 23 RTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVATTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 26-99 5.36e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 61.93  E-value: 5.36e-14
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 813424642 26 RKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFVL--FFLTLAACEGALGLALLVSVVRTHGNDCFSSFSVLQC 99
Cdd:MTH00067 23 RTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLpmFMLTFSACEASTGLALMVATTRTHGTDHLKNLNLLQC 98
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 12-99 1.91e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 60.24  E-value: 1.91e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642 12 VVSVLCGLWVFVSKRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFVLFFLTLAACEGALGLALLVSVVRTHGNDCF 91
Cdd:MTH00149 10 LFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGNDYV 89


                ....*...
gi 813424642 92 SSFSVLQC 99
Cdd:MTH00149 90 SSLSSLKF 97
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 26-99 1.33e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 58.05  E-value: 1.33e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 813424642 26 RKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFV--LFFLTLAACEGALGLALLVSVVRTHGNDCFSSFSVLQC 99
Cdd:MTH00126 23 RTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAapMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 26-99 3.08e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 54.55  E-value: 3.08e-11
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 813424642 26 RKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESYFV--LFFLTLAACEGALGLALLVSVVRTHGNDCFSSFSVLQC 99
Cdd:MTH00107 23 RSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMmpIILLVFAACEAAVGLALLVMVSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
6-99 5.73e-11

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 53.72  E-value: 5.73e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642   6 FYYIVPVVSVLCGLWVFVSkRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGH--ESYFVLFFLTLAACEGALGLALLVSVV 83
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADplPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 813424642  84 RTHGNDCFSSFSVLQC 99
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 4-98 1.08e-08

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 47.99  E-value: 1.08e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642  4 LNFYYIVPVVSVLCGLWVFVSKRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGHESY--FVLFFLTLAACEGALGLALLVS 81
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*..
gi 813424642 82 VVRTHGNDCFSSFSVLQ 98
Cdd:MTH00043 81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 13-99 1.76e-08

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 47.44  E-value: 1.76e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642 13 VSVLCGLWVFVSKRKHLLNTLLSLEYIMLSIFWIMSLHLSNMGH-ESYFVLFFLTLAACEGALGLALLVSVVRTHGNDCF 91
Cdd:MTH00013 10 ISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFANQvNGMLAIVLLTFGACEASLGLSLLVLMTRSYGNDML 89


                ....*...
gi 813424642 92 SSFSVLQC 99
Cdd:MTH00013 90 KSLTSNKC 97
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 25-97 2.43e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 41.85  E-value: 2.43e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 813424642 25 KRKHLLNTLLSLEYIMLSIFWIMSLH--LSNMGHESYFVLFFLTLAACEGALGLALLVSVVRTHGNDCFSSFSVL 97
Cdd:MTH00181 19 YKTHLLSLLLCLEGMMLFLFLLLALFslLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSDHLLKFNLL 93
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 4-88 1.70e-04

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 37.35  E-value: 1.70e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642  4 LNFYYIVPVVSVLCGLWVFVSkRKHLLNTLLSLEyIMLS----IFWIMSLHLSNMGHESyFVLFFLTLAACEGALGLALL 79
Cdd:COG0713   3 LEHYLILAAILFAIGLYGVLT-RRNLIVVLMSIE-LMLNavnlNLVAFSRYLGDLDGQV-FALFVIAVAAAEVAVGLAII 79


                ....*....
gi 813424642 80 VSVVRTHGN 88
Cdd:COG0713  80 VALYRNRGT 88
PRK05715 PRK05715
NADH-quinone oxidoreductase subunit NuoK;
1-97 2.00e-03

NADH-quinone oxidoreductase subunit NuoK;


Pssm-ID: 180218  Cd Length: 100  Bit Score: 34.38  E-value: 2.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 813424642   1 MLILNFYYIVPVVSVLCGLWVfVSKRKHLLNTLLSLEYIMLSI---FWIMSLHLSNMGHEsYFVLFFLTLAACEGALGLA 77
Cdd:PRK05715   1 MIPLQHYLILAAILFCIGLVG-LLLRRNAIVVLMSIELMLNAVnlnFVAFSSYLGDLDGQ-VFAFFVITVAAAEAAIGLA 78

                         90       100
                 ....*....|....*....|
gi 813424642  78 LLVSVVRTHGNDCFSSFSVL 97
Cdd:PRK05715  79 ILLQLYRNRGTIDVDDLNEL 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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