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Conserved domains on  [gi|910356015|ref|YP_009161895|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Stylodipus telum]

Protein Classification

NADH-ubiquinone oxidoreductase chain 4L( domain architecture ID 10009568)

NADH-ubiquinone oxidoreductase chain 4L is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) and is believed to belong to the minimal assembly required for catalysis; Complex I functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 4.95e-40

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177169  Cd Length: 98  Bit Score: 127.74  E-value: 4.95e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  1 MPLIYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVT 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 910356015 81 ISNSYGNDYVQNLNLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 4.95e-40

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 127.74  E-value: 4.95e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  1 MPLIYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVT 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 910356015 81 ISNSYGNDYVQNLNLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 1.43e-15

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 65.66  E-value: 1.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015   3 LIYTSLTLAFSLSLLGtLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVTIS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYG-LLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 910356015  83 NSYGNDYVQNLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 12-96 9.63e-06

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 40.43  E-value: 9.63e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015 12 FSLSLLGtLMFRSHLMSTLLCLEGMMLAI---FVTTSistlSTHNNLSF-MLPIIILVFAACEAAVGLALLVTISNSYGN 87
Cdd:COG0713  14 FAIGLYG-VLTRRNLIVVLMSIELMLNAVnlnLVAFS----RYLGDLDGqVFALFVIAVAAAEVAVGLAIIVALYRNRGT 88


                ....*....
gi 910356015 88 DYVQNLNLL 96
Cdd:COG0713  89 IDVDDLNEL 97
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 4.95e-40

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 127.74  E-value: 4.95e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  1 MPLIYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVT 80
Cdd:MTH00107  1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                        90
                ....*....|....*...
gi 910356015 81 ISNSYGNDYVQNLNLLQC 98
Cdd:MTH00107 81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.45e-25

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 91.06  E-value: 1.45e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  1 MPLIYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVT 80
Cdd:MTH00125  1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                        90
                ....*....|....*...
gi 910356015 81 ISNSYGNDYVQNLNLLQC 98
Cdd:MTH00125 81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 5.77e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 84.63  E-value: 5.77e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  1 MPLIYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVT 80
Cdd:MTH00126  1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                        90
                ....*....|....*...
gi 910356015 81 ISNSYGNDYVQNLNLLQC 98
Cdd:MTH00126 81 TARTHGTDRLQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 8.98e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 81.57  E-value: 8.98e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  1 MPLIYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVT 80
Cdd:MTH00067  1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVA 80

                        90
                ....*....|....*...
gi 910356015 81 ISNSYGNDYVQNLNLLQC 98
Cdd:MTH00067 81 TTRTHGTDHLKNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 1.43e-15

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 65.66  E-value: 1.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015   3 LIYTSLTLAFSLSLLGtLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVTIS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYG-LLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 910356015  83 NSYGNDYVQNLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 4-96 8.45e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 56.11  E-value: 8.45e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  4 IYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVTISN 83
Cdd:MTH00181  1 MMFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNR 80

                        90
                ....*....|...
gi 910356015 84 SYGNDYVQNLNLL 96
Cdd:MTH00181 81 THGSDHLLKFNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 3.86e-11

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 54.54  E-value: 3.86e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  1 MPLIYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVT 80
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*..
gi 910356015 81 ISNSYGNDYVQNLNLLQ 97
Cdd:MTH00043 81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 9-98 1.07e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 50.61  E-value: 1.07e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  9 TLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVttSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVTISNSYGND 88
Cdd:MTH00149 10 LFGFLMGVFALLFQYKHLLSILLSLEALMLSLLV--MMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGND 87

                        90
                ....*....|
gi 910356015 89 YVQNLNLLQC 98
Cdd:MTH00149 88 YVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 12-98 1.59e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 50.36  E-value: 1.59e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015 12 FSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSThnNLSFMLPIIILVFAACEAAVGLALLVTISNSYGNDYVQ 91
Cdd:MTH00188 13 VVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYM--EKELYLSLVLLTFAACEASVGLALLVSLIRSHGSDYVS 90


                ....*..
gi 910356015 92 NLNLLQC 98
Cdd:MTH00188 91 SLNLIKC 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 12-92 9.07e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 42.83  E-value: 9.07e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015 12 FSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVttSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVTISNSYGNDYVQ 91
Cdd:MTH00162 11 FFSGLLVFLSKRKHLLLMLLSLEFMVLSLFF--LLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRSHGNDYFS 88


                .
gi 910356015 92 N 92
Cdd:MTH00162 89 S 89
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 8-98 1.58e-06

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 42.43  E-value: 1.58e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  8 LTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSIStLSTHNNLSFMLPIIILVFAACEAAVGLALLVTISNSYGN 87
Cdd:MTH00013  8 LSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLS-LMFANQVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGN 86

                        90
                ....*....|.
gi 910356015 88 DYVQNLNLLQC 98
Cdd:MTH00013 87 DMLKSLTSNKC 97
NuoK COG0713
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; ...
 12-96 9.63e-06

NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440477  Cd Length: 99  Bit Score: 40.43  E-value: 9.63e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015 12 FSLSLLGtLMFRSHLMSTLLCLEGMMLAI---FVTTSistlSTHNNLSF-MLPIIILVFAACEAAVGLALLVTISNSYGN 87
Cdd:COG0713  14 FAIGLYG-VLTRRNLIVVLMSIELMLNAVnlnLVAFS----RYLGDLDGqVFALFVIAVAAAEVAVGLAIIVALYRNRGT 88


                ....*....
gi 910356015 88 DYVQNLNLL 96
Cdd:COG0713  89 IDVDDLNEL 97
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 1-97 1.84e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 39.63  E-value: 1.84e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  1 MPLIYTSLTLAFSLSLLGTLMFRSHLMSTLLCLEGMMLAIFVTTSISTLSTHNNLSFMLPIIILVFAACEAAVGLALLVT 80
Cdd:MTH00180  2 YYEYLTVGIILFILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNLIGQIFTIMILTVAAAESAIGLAILVA 81

                        90
                ....*....|....*..
gi 910356015 81 ISNSYGNDYVQNLNLLQ 97
Cdd:MTH00180 82 YYRIRGTIAVKSLNLLR 98
PRK05715 PRK05715
NADH-quinone oxidoreductase subunit NuoK;
12-96 7.64e-04

NADH-quinone oxidoreductase subunit NuoK;


Pssm-ID: 180218  Cd Length: 100  Bit Score: 35.54  E-value: 7.64e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 910356015  12 FSLSLLGtLMFRSHLMSTLLCLEGMMLAI---FVTTSistlSTHNNLS-FMLPIIILVFAACEAAVGLALLVTISNSYGN 87
Cdd:PRK05715  15 FCIGLVG-LLLRRNAIVVLMSIELMLNAVnlnFVAFS----SYLGDLDgQVFAFFVITVAAAEAAIGLAILLQLYRNRGT 89


                 ....*....
gi 910356015  88 DYVQNLNLL 96
Cdd:PRK05715  90 IDVDDLNEL 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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