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Conserved domains on  [gi|992329291|ref|YP_009227682|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Pampus cinereus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 534.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   1 MSPFTLLILLFSLGLGTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWI 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  81 TGQWEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTNPTLLILLGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 241 ALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLYSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 992329291 321 HTLPTATSITATLLLLPITPAVIAVMN 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 534.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   1 MSPFTLLILLFSLGLGTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWI 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  81 TGQWEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTNPTLLILLGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 241 ALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLYSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 992329291 321 HTLPTATSITATLLLLPITPAVIAVMN 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 4.70e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 99.70  E-value: 4.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   23 SSHWLLAWMGLEINTLAIIPLMA-QKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMTHPLPTT----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   97 ------MITLALALKIGLAPTHAWLPEVLQGLDLTTGLIL-STWQKLAPFTLLMQI---HPTNPT---LLILLGLTSTLV 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSllyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  164 GGWGGLNQTQLRKILAYSSIAHLGWMTLIM----QFLPSLAFMTLLTYFIMTFSTFLVFKL-----NNTTNINTLATSWT 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 992329291  235 KTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 19-299 2.05e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 91.72  E-value: 2.05e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  19 ITMTSS-HWLLAWMGLEINTLAIIPLMA-QKHHPRAVEATTKYFLTQATAAAMLLFASttnAWI---TGQWEIQQMTHPL 93
Cdd:COG1007  116 MLMASAnDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGI---SLLygaTGSLNLAGIAAAL 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  94 PTT------------MITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQI--------HPTNPTLL 153
Cdd:COG1007  193 AAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveafpglAADWQLLL 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 154 ILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMT----LLTYFIMTFSTFLVF-----KLNNTT 224
Cdd:COG1007  273 AVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAalfyLLAYLFMNLGAFAVIlllsrKGGEAE 352

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 992329291 225 NINTLATSWTKTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAM 299
Cdd:COG1007  353 EIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVKAM 427
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 16-299 9.54e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 83.84  E-value: 9.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   16 GTIITMTSSHWLLAWMGLEINTLAIIPLMA-QKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMTHPLP 94
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   95 TTMIT------------LALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQI--------HPTNPTLLI 154
Cdd:TIGR01770 194 NGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLflyilfgfSEAWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  155 LLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGW----MTLIMQFLPSLAFMTLLTYFIMTFSTFLVF------KLNNTT 224
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiligLLAGTLEGIKAVLFYIFIYALMSLGAFGVLsllrsyKDEWIE 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 992329291  225 NINTLATSWTKTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAM 299
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 534.38  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   1 MSPFTLLILLFSLGLGTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWI 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  81 TGQWEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTNPTLLILLGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 241 ALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLYSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 992329291 321 HTLPTATSITATLLLLPITPAVIAVMN 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 9.27e-138

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 395.06  E-value: 9.27e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   1 MSPFTLLILLFSLGLGTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWI 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  81 TGQWEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPT-NPTLLILLGLT 159
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 240 TALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLyST 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330       340
                 ....*....|....*....|....*..
gi 992329291 320 QHTLPTATSITATLLLLPITPAVIAVM 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 1.88e-121

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 353.36  E-value: 1.88e-121
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   1 MSPFTLLILLFSLGLGTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWI 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  81 TGQWEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHP-TNPTLLILLGLT 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNsLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 240 TALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLYST 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*..
gi 992329291 320 QHTLpTATSITATLLLLPITPAVIAVM 346
Cdd:MTH00112 321 KNTL-TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-343 4.85e-119

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 347.60  E-value: 4.85e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   1 MSPFTLLILLFSLGLGTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWI 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  81 TGQWEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPT-NPTLLILLGLT 159
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSiNPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 240 TALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLYST 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....
gi 992329291 320 QHTLPTATSITATLLLLPITPAVI 343
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLS 344
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 2.79e-105

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 312.29  E-value: 2.79e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   1 MSPFTLLILLFSLGLGTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWI 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  81 TGQWEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHP-TNPTLLILLGLT 159
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPaLNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 240 TALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLYST 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*..
gi 992329291 320 QHtLPTATSITATLLLLPITPAVIAVM 346
Cdd:MTH00200 321 SN-LLVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 16-340 3.95e-86

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 263.71  E-value: 3.95e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMTHPLPT 95
Cdd:MTH00041  16 GTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSS 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  96 TMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQI-HPTNPTLLILLGLTSTLVGGWGGLNQTQL 174
Cdd:MTH00041  96 IIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsNLLNSNILILCGILSVLVGGWGGLNQTQT 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 175 RKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTLTALTPLVLLSLGGLP 254
Cdd:MTH00041 176 RKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLP 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 255 PLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLYSTQHTLPTATSITATLL 334
Cdd:MTH00041 256 PLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGVILSILSSIS 335


                 ....*.
gi 992329291 335 LLPITP 340
Cdd:MTH00041 336 ILGLLL 341
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 16-311 1.80e-58

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 191.96  E-value: 1.80e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGqweiqqMTHPLPT 95
Cdd:MTH00160  17 GTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM------LFNNISS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  96 TMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIhpTNPTLLILLGLTSTLVGGWGGLNQTQLR 175
Cdd:MTH00160  91 MLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL--INNNFIIIIIILSAIIGAIGGLNQTSLR 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 176 KILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTLTALTPLVLLSLGGLPP 255
Cdd:MTH00160 169 KILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPP 248

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 992329291 256 LTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSI 311
Cdd:MTH00160 249 FLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNL 304
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 16-310 2.14e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 170.84  E-value: 2.14e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIqqmthplpT 95
Cdd:MTH00144  16 GTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS--------M 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  96 TMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTNP--TLLILLGLTSTLVGGWGGLNQTQ 173
Cdd:MTH00144  88 SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlaYLLCVISVLSALVGSIGGLNQTQ 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 174 LRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLatSWTKTPTLTALTPLVLLSLGG- 252
Cdd:MTH00144 168 VRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL--GSLKPSYKTGLSIISLLLSLGg 245

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 992329291 253 LPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSS 310
Cdd:MTH00144 246 LPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSN 303
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 16-304 1.11e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 161.10  E-value: 1.11e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTnawitgQWEIQQMTHPLPT 95
Cdd:MTH00011  18 GTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWSFPSLLKNITA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  96 TMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTNPTLLIL-LGLTSTLVGGWGGLNQTQL 174
Cdd:MTH00011  92 LMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTsMAAMSALAGGLGGMNQTQL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 175 RKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTLTALTPLVLLSLGGLP 254
Cdd:MTH00011 172 RPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLP 251

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 992329291 255 PLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMS 304
Cdd:MTH00011 252 PFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSP 301
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 16-297 1.18e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 142.50  E-value: 1.18e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFasttnawitGQWEIQQ--MTHPL 93
Cdd:MTH00197  10 GVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLM---------GGSLSFSnlYLSLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  94 PTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHpTNPTLLILLGLTSTLVGGWGGLNQTQ 173
Cdd:MTH00197  81 SVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNS-SSFMGLLICSVLSSLIGGIGGMNQSN 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 174 LRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLATSWTKTPTLTALTPLVLLSLGGL 253
Cdd:MTH00197 160 IRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGL 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 992329291 254 PPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLY 297
Cdd:MTH00197 240 PPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-267 4.70e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 99.70  E-value: 4.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   23 SSHWLLAWMGLEINTLAIIPLMA-QKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMTHPLPTT----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   97 ------MITLALALKIGLAPTHAWLPEVLQGLDLTTGLIL-STWQKLAPFTLLMQI---HPTNPT---LLILLGLTSTLV 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSllyLPSSPFiqqILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  164 GGWGGLNQTQLRKILAYSSIAHLGWMTLIM----QFLPSLAFMTLLTYFIMTFSTFLVFKL-----NNTTNINTLATSWT 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 992329291  235 KTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQ 267
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-295 7.28e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 97.79  E-value: 7.28e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHP-RAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQ------- 87
Cdd:MTH00196   5 GILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSyinlvln 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  88 ------QMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPtNPTLLILLGLTST 161
Cdd:MTH00196  85 sgqsfsSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL-NVNILLIGGLFSL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 162 LVGGWGGLNQTQLRKILAYSSIAHLGWMTL------IMQFLPSLAFMTLltYFIMT---FSTFLVFKLNNTTNINTLATS 232
Cdd:MTH00196 164 FVGAIGALNQTKIKRLLAYSGIGHMGFVLWgieigsFESIQASLVYLFI--YIIMSicvFSIILALNVYKNLIIEFSGLS 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 992329291 233 wTKTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRL 295
Cdd:MTH00196 242 -RRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 16-266 9.53e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 98.55  E-value: 9.53e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHP-RAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQ----MT 90
Cdd:MTH00199 109 GSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSaYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGinsiLT 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  91 HPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTNPTLLILLGLtSTLVGGWGGLN 170
Cdd:MTH00199 189 GDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVL-SIIYGAIGALN 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 171 QTQLRKILAYSSIAHLG---WMTLIMQFLPSLA-FMTLLTYFIMTFSTF-LVFKLNNTTN-INTLATSWTKTPTLTALTP 244
Cdd:MTH00199 268 QTKIKRLLAYSGIGHMGfilFGVAIGSFESIQAsLIYMIIYVIMSICSFsIILSLKLTKGlIVEVSGLSRKNPVIALTLA 347

                        250       260
                 ....*....|....*....|..
gi 992329291 245 LVLLSLGGLPPLTGFMPKWLIL 266
Cdd:MTH00199 348 LTFLSIAGIPPLAGFLSKWLIL 369
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 19-299 2.05e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 91.72  E-value: 2.05e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  19 ITMTSS-HWLLAWMGLEINTLAIIPLMA-QKHHPRAVEATTKYFLTQATAAAMLLFASttnAWI---TGQWEIQQMTHPL 93
Cdd:COG1007  116 MLMASAnDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGI---SLLygaTGSLNLAGIAAAL 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  94 PTT------------MITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQI--------HPTNPTLL 153
Cdd:COG1007  193 AAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLlveafpglAADWQLLL 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 154 ILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMT----LLTYFIMTFSTFLVF-----KLNNTT 224
Cdd:COG1007  273 AVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVSAalfyLLAYLFMNLGAFAVIlllsrKGGEAE 352

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 992329291 225 NINTLATSWTKTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAM 299
Cdd:COG1007  353 EIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVKAM 427
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 16-299 9.54e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 83.84  E-value: 9.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   16 GTIITMTSSHWLLAWMGLEINTLAIIPLMA-QKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMTHPLP 94
Cdd:TIGR01770 114 GIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLS 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   95 TTMIT------------LALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQI--------HPTNPTLLI 154
Cdd:TIGR01770 194 NGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLflyilfgfSEAWQIFLA 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  155 LLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGW----MTLIMQFLPSLAFMTLLTYFIMTFSTFLVF------KLNNTT 224
Cdd:TIGR01770 274 IIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiligLLAGTLEGIKAVLFYIFIYALMSLGAFGVLsllrsyKDEWIE 353

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 992329291  225 NINTLATSWTKTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAM 299
Cdd:TIGR01770 354 YISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
16-299 7.55e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 81.41  E-value: 7.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMA-QKHHPRAVEATTKYFLTQATAAAMLLF---------ASTTNAWITGQWE 85
Cdd:PRK05777 115 GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygatGSLSFAGIAKALA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  86 IQQMTHPLPTT---MITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQI--------HPTNPTLLI 154
Cdd:PRK05777 195 DGSGNSLLLLFglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLlvvafgglSEDWQQVLA 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 155 LLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLA----FMTLLTYFIMTFSTFLVF-----KLNNTTN 225
Cdd:PRK05777 275 IIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGysavLFYLLAYLFMTLGAFGVIsllrrKGGEAES 354

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 992329291 226 INTLATSWTKTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAM 299
Cdd:PRK05777 355 ISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVIKLM 428
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-238 2.32e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 71.04  E-value: 2.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAV---------EATTKYFLTQATAAAMLLFASTTNAWITGQ--- 83
Cdd:MTH00198 200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegm 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  84 -----------WEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTNpTL 152
Cdd:MTH00198 280 lgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITS-KL 358

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 153 LILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFImtfsTFLVFKLNNTTNINTLATS 232
Cdd:MTH00198 359 LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV----TYLVSALASFTVICTLEEF 434


                 ....*.
gi 992329291 233 WTKTPT 238
Cdd:MTH00198 435 GTRTPT 440
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 30-267 1.01e-11

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 65.55  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  30 WMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMTHPLPT----------TMIT 99
Cdd:COG0651  133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAEldpglllaafALLL 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 100 LALALKIGLAPTHAWLPE-----------VLQGLDLTTGL--ILSTWQKLAPFTLLMQIHPtnptLLILLGLTSTLVGGW 166
Cdd:COG0651  213 VGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLGT----LLLVLGLLTMLVGAL 288

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 167 GGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFI--MTFSTFL------VFKLNNTTNINTLATSWTKTPT 238
Cdd:COG0651  289 GALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLnhALAKALLflaagaIERATGTRDLDKLGGLGKRMPL 368

                        250       260
                 ....*....|....*....|....*....
gi 992329291 239 LTALTPLVLLSLGGLPPLTGFMPKWLILQ 267
Cdd:COG0651  369 TAAAFLIGALALAGLPPLSGFVSKWLLLQ 397
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 4.34e-09

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 51.87  E-value: 4.34e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 992329291  290 YFYLRLLYAMTLTMSPNNTSSITCWRLYSTQHTLPTATSITATLLLLPITP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-191 1.07e-07

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 53.40  E-value: 1.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  20 TMTSSHWLLAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFL------TQATAAAMLLFASTTNAWITGQ----W-EIQQ 88
Cdd:PRK06458 124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYANAATVMGDGEmailWtELLK 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  89 MTHPLPTTMITLALAL-------KIGLAPTHAWLPE-----------VLQGLDLTTGLILstwqkLAPFTLLMQIHPTN- 149
Cdd:PRK06458 204 HASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYA-----VLRYYILIDAAIGSd 278

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 992329291 150 --PTLLILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTL 191
Cdd:PRK06458 279 fpGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-318 4.59e-07

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 51.16  E-value: 4.59e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  51 RAVEATTKYFLTQATAAAMLLFA-STTNAWITGQWEIQQMTHPLPTT-------------MITLALALKIGLAPTHAWLP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGfSWLYGLSGGEIELQEIVNGLINTqmynspgisialiFITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 117 EVLQGLDLTTGLILSTWQKLAPFTLLMQI----HPTNPT----LLILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGW 188
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAASALATRIfdipFYFSSNewhlLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 189 MTL-IMQFLPSLAFMTLLTYFIM-------TFSTFLVFKLNN-TTNINTLATSWTKTPTLTALTPLVLLSLGGLPPLTGF 259
Cdd:CHL00049 319 VIIgIIVGDSNDGYASMITYMLFyifmnlgTFACIVLFGLRTgTDNIRDYAGLYTKDPFLALSLALCLLSLGGIPPLAGF 398

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 992329291 260 MPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAMTLTMSPNNTSSITCWRLYS 318
Cdd:CHL00049 399 FGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKIIKLLMTGRNQEITPYVRNYRRSP 457
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 44-299 7.85e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 50.74  E-value: 7.85e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  44 MAQKHHPRAVEATTKYFLTQATAAAMLLFA--------STTN-----AWITGQWEIQQMT---HPLPTTMITLALAL--- 104
Cdd:PRK12667 154 AYYRDRGDAVEAAIKYALIGAVGTTLYFLAlaflyatfGTLNmadlsAKIRGLSFPLTGGlagNPPLALGVALALALwaf 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 105 --KIGLAPTHAWLPEV-----------LQGLDLTTG---------LILSTWQKLAPFTLLMQIhptnptLLILLGLTSTL 162
Cdd:PRK12667 234 tiKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAALSP------ILIILGAVSAI 307

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 163 VGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFI-------MTFSTFLVF-KLNNTTNINTLATSWT 234
Cdd:PRK12667 308 IGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaiaksLLFLASGVFiHAAGTRDIDELAGLGR 387

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 992329291 235 KTPTLTALTPLVLLSLGGLPPLTGFMPKWLILQELSKQELALVATTAALTALLSLYFYLRLLYAM 299
Cdd:PRK12667 388 KMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSL 452
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-191 7.90e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 50.46  E-value: 7.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  49 HPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQW--EIQQ-MTHPLPTTM-------ITLALALKIGLAPTHAWLPE- 117
Cdd:COG1008  156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAElAAAPLPLTAqlllflaFFIAFAVKVPMFPFHTWLPDa 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 118 ----------VLQGLDLTTG----------LILSTWQKLAPftllmqihptnptLLILLGLTSTLVGGWGGLNQTQLRKI 177
Cdd:COG1008  236 hveaptagsvLLAGVLLKMGgygllrfalpLFPEASAYFAP-------------LLAALGVIGIIYGALVALAQTDLKRL 302

                        170
                 ....*....|....
gi 992329291 178 LAYSSIAHLGWMTL 191
Cdd:COG1008  303 IAYSSVSHMGFVLL 316
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 50-191 2.31e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 49.17  E-value: 2.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291   50 PRAVEATTKYFLTQATAAAMLLFASTTNAWITG------QWEIQQMTHPLPTTM---ITLALALKIGLAPTHAWLPEV-L 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGgtfdllELLNLPLPFGVQTWLflaFFIAFAVKVPLFPLHTWLPDAhV 231

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 992329291  120 QGLDLTTGLILSTWQKLAPFTLLMQIHPTNP-------TLLILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTL 191
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFLRFNLPLFPdaslyfaPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLL 310
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-202 7.60e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.57  E-value: 7.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  33 LEINTLAIIPLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMTHPLP--------TTMITLALAL 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGALAenptvvtaFGFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 105 KIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQI-----------HPTNPTLLILLGLTSTLVGGWGGLNQTQ 173
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPPVVTALLSGLVTKVAVYALIRIyftvfggdfrfALGLGWLLAVLALLSMLVGSLAALGQDD 294

                        170       180
                 ....*....|....*....|....*....
gi 992329291 174 LRKILAYSSIAHLGWMTLIMQFLPSLAFM 202
Cdd:PRK08375 295 VKRVLAYSTVSQMGYILLGLALLTPLALA 323
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 50-191 3.41e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 45.58  E-value: 3.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  50 PRAVEATTKYFL-TQATAAAML---LFASTTNAWITGQWEIQQ-MTHPLPTTMITL-------ALALKIGLAPTHAWLPE 117
Cdd:PRK05846 157 KNRIYAATKFFLyTLLGSLLMLvaiIYLVVVYYNATGTFDIADlLNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 118 VLQ-----GLDLTTGLILstwqKLAPFTLL---MQIHPTNP----TLLILLGLTSTLVGGWGGLNQTQLRKILAYSSIAH 185
Cdd:PRK05846 237 AHVqaptaGSVLLAGILL----KMGAYGLLrfsLPLFPDAShefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISH 312


                 ....*.
gi 992329291 186 LGWMTL 191
Cdd:PRK05846 313 MGFVTL 318
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
47-262 3.48e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 45.43  E-value: 3.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  47 KHHPRAVEATTKYFLTQATAAAMLLF-ASTTNAWITGQWEIQQMTHPL---PTTMITLAL-------ALKIGLAPTHAWL 115
Cdd:PRK02504 154 KRDPRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSAIALALitsPSLGLALALvfviagiAFKISAVPFHQWT 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 116 PEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTN--------PTLLILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLG 187
Cdd:PRK02504 234 PDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAfpsfdeqwKLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAG 313

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 188 WMT--LIMQFLPSLAFMT--LLTYFIMT---FSTFLVFKLNNTTN-INTLATSWTKTPTLTALTPLVLLSLGGLPPLTGF 259
Cdd:PRK02504 314 FVMigLVAGTEAGYASMVfyLLAYLFMNlgaFACVILFSLRTGTDqISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGF 393


                 ...
gi 992329291 260 MPK 262
Cdd:PRK02504 394 FGK 396
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 3.55e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 45.47  E-value: 3.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  33 LEINTLAIIPLMAQKHH-PRAVEATTKYFLTQATAAAMLLFASttnAWITGQWEIQQMTH--------PLPTTMITLA-- 101
Cdd:PRK08376 150 LEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYlavkmsenPTVVAKIALAlf 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 102 ---LALKIGLAPTHAWLPEVLQGL--DLTTGLILSTWQKL-APFTLLMQIH------PTNPTLLILLGLTSTLVGGWGGL 169
Cdd:PRK08376 227 iagLAMKSGAVPVHMWLPDAYPAApsSISAMLLVIKQAGLyALARVLFSIYgpainlATVGWVIIILGCLTMFVGVAMAV 306

                        170       180
                 ....*....|....*....|..
gi 992329291 170 NQTQLRKILAYSSIAHLGWMTL 191
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLL 328
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
38-191 3.53e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 42.38  E-value: 3.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  38 LAIIPL---MAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEI---QQMTHPLPTTM-------ITLALAL 104
Cdd:PRK06473 138 LELIPLyllIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGASSFdyePLRSHTLPLSTqllllapILVGFGI 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 105 KIGLAPTHAWLPE-----------VLQG--LDLTT--------GLILSTWQKLAPFtllmqihptnptlLILLGLTSTLV 163
Cdd:PRK06473 218 KIPLVPFHTWLPDahveastpvsvLLAGvlLKLGTygllrfgvGLFPEAWVYLAPW-------------LATWAVVSVLY 284

                        170       180
                 ....*....|....*....|....*...
gi 992329291 164 GGWGGLNQTQLRKILAYSSIAHLGWMTL 191
Cdd:PRK06473 285 GASCAIAQKDMKKMVAYSSIGHMGYILL 312
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
19-191 3.67e-04

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 42.38  E-value: 3.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  19 ITMTSSHWLL---AWM--GLEINTLaiipLMAQKHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQ----- 88
Cdd:PRK08168 115 LLVLSDHLLVliaAWAaiSLALHRL----LCFYPDRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSLSAlwahl 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  89 ----MTHPLPTTMITLALA--LKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTL-----LMQIHPTNPTLLILLG 157
Cdd:PRK08168 191 aaqgASPSLQAAALLLVLAviLKTAQLPVHGWLIQVMEAPTPVSALLHAGVVNLGGFVLirfapLLEQAPPARWLLVLVG 270

                        170       180       190
                 ....*....|....*....|....*....|....
gi 992329291 158 LTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTL 191
Cdd:PRK08168 271 LATAVLAGLVMLTRISIKVRLAWSTVAQMGFMLL 304
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 81-192 4.76e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 42.22  E-value: 4.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  81 TGQWEIQQM-THPLPTTMITLALAL-------KIGLAPTHAWLPE-----------------VLQGLDLTTglilstwqK 135
Cdd:PRK12644 184 AGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGamaaptpvsaylhaaamVKAGIYLVA--------R 255

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 992329291 136 LAP-FTLLMQIHPTnptlLILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTLI 192
Cdd:PRK12644 256 LAPgFADVPVWRPT----VLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVL 309
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 28-209 7.40e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 41.28  E-value: 7.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  28 LAWMGLEINTLAIIPLMAQKHHPRAVEATTKYFLTQATA------AAMLLFASTTNAWITG--QW-EIQQMTHPLPTTMI 98
Cdd:PRK08676 126 LFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNWtELAAHASLLSPSVL 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  99 TLA-------LALKIGLAPTHAWLPE-----------VLQGLDLTTGLilstWQKLAPFTLLMQ--IHPTNPTLLILLGL 158
Cdd:PRK08676 206 GASflfifigFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGI----YGILRLSALLRQsgAAEQFSNVLIGLGI 281

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 992329291 159 TSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAFMTLLTYFI 209
Cdd:PRK08676 282 FSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-193 1.11e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 40.68  E-value: 1.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  98 ITLALALKIGLAPTHAWLPEV-----LQGLDLTTGLILstwqKLAPFTLLMQIHPTNP-------TLLILLGLTSTLVGG 165
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILL----KLGGYGLVRLSWPILPlgaqnlaPAVIAMGIVGIVYGS 311

                         90       100
                 ....*....|....*....|....*...
gi 992329291 166 WGGLNQTQLRKILAYSSIAHLGWMTLIM 193
Cdd:MTH00226 312 FATCRQIDVKRLVAYSSVAHMGLVSITL 339
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 47-189 1.17e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 40.97  E-value: 1.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  47 KHHPRAVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMT---------HPLPTTMITLAL-----ALKIGLAPTH 112
Cdd:PRK12649 155 RHRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILqdselieniKGHPLFLITLILifigaAAKSAQGPFY 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 113 AWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPT---NPTLLILL---GLTSTLVGGWGGLNQTQLRKILAYSSIAHL 186
Cdd:PRK12649 235 IWLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIfsgTEAWFILVsgtGMITMVLAGFLAFRQTDIKAILAYSTISQL 314


                 ...
gi 992329291 187 GWM 189
Cdd:PRK12649 315 AYL 317
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 97-271 1.36e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 39.85  E-value: 1.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  97 MITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTNPTLLILLGLTSTLVGGWgglNQTQLRK 176
Cdd:MTH00091  62 FQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMF---LLKSYKN 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 177 ILAYSSIAHLGWMtlIMQFLPSLAFMTLLTYFIMTFSTFLVFKLNNTTNINTLatSWTKTPTLTALTPLVllslgglppl 256
Cdd:MTH00091 139 LLILSSTESFNWL--ILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFV--SWETLLVFMNLPFSV---------- 204

                        170
                 ....*....|....*
gi 992329291 257 tGFMPKWLILQELSK 271
Cdd:MTH00091 205 -TFFVKIFSLSEILK 218
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 100-191 1.98e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 40.05  E-value: 1.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 100 LALALKIGLAPTHAWLPEV-----LQGLDLTTGLILstwqKLAPFTLLMQIHPTNPT-------LLILLGLTSTLVGGWG 167
Cdd:MTH00204 217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGYGFLRFSWPLFPAaseyfapLIVMLSVIAVIYGSLT 292

                         90       100
                 ....*....|....*....|....
gi 992329291 168 GLNQTQLRKILAYSSIAHLGWMTL 191
Cdd:MTH00204 293 TCRQVDFKRLIAYSSVAHMGLVPL 316
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
52-193 3.09e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 39.24  E-value: 3.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  52 AVEATTKYFLTQATAAAMLLFASTTNAWITGQWEIQQMTHPL----PTTMITLALALKIGLA------------PTHAWL 115
Cdd:PRK07376 171 AADAAQKAFVVNRVGDFGLLLGILGLFWATGSFDFDGIADRLselvSSGAVSGWLALLLCILvflgpmaksaqfPLHVWL 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 116 PEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPTN---PTLLILLGLTSTL---VGGWGGLNQTQLRKILAYSSIAHLGWM 189
Cdd:PRK07376 251 PDAMEGPTPISALIHAATMVAAGVFLVARMYPVFeqfPAVMTVIAWTGAItafLGASIALTQNDIKKGLAYSTISQLGYM 330


                 ....
gi 992329291 190 TLIM 193
Cdd:PRK07376 331 VMAM 334
ND5 MTH00211
NADH dehydrogenase subunit 5; Provisional
 68-206 3.46e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214459 [Multi-domain]  Cd Length: 597  Bit Score: 39.16  E-value: 3.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  68 AMLLFASTTNAWITGQWEIQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHP 147
Cdd:MTH00211 180 SMVWLLLNLNSWEISQLFILNLDLTLFLLGLLLAAMGKSAQFGFHPWLPSAMEGPTPVSALLHSSTMVVAGVFLLIRLSP 259

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 992329291 148 TNP------TLLILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTL-IMQFLPSLAFMTLLT 206
Cdd:MTH00211 260 LFQnnqlilGAVLLLGALTMLFGALCALTQNDIKKIVAFSTTSQLGLMMVtLGLNQPQLAFLHICT 325
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
55-191 3.72e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 38.92  E-value: 3.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  55 ATTKYFLTQATAAAMLLFASTTNAWITGQWE----------IQQMTHPLPTTMITLALALKIGLAPTHAWLPEVLQGLDL 124
Cdd:PRK07363 158 ASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSfdydaistqnLSLNTQLILLTGLLLGFGIKIPLVPLHTWLPDAYTEASP 237

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 992329291 125 TTGLILS-TWQKLAPFTLL---MQIHP-----TNPTLLILlGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTL 191
Cdd:PRK07363 238 AVAILLGgVLAKLGTYGLLrfgLQLFPqtwslVAPGLAII-GTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILV 312
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 16-269 4.17e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 38.82  E-value: 4.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  16 GTIITMTSSHWLLAWMGLEINTLA--IIPLMAQKhhpRAVEATTKYFLTQATAAAMLLFASTTNAWITGQW---EIQQMT 90
Cdd:PRK08668 110 GVLGVFLANDLLTLYIFWEIMTFSsfMMVPMGKK---ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFdfaDISQGL 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291  91 HPLPTTMITLALAL--------KIGLAPTHAWLPEVLQGLDLTTGLILS-TWQKLAPFTLLMQI---------------- 145
Cdd:PRK08668 187 INDTSTGFALIVFLfllafgvaKAGIFPLHVWAPDAYSEAPQSFSAVLSgQLSKLGAYGFLLVLyvlpgtklfsefgtyr 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 146 -HPTNPTLLILLGLTSTLVGGWGGLNQTQLRKILAYSSIAHLGWMTLIMQFLPSLAF----MTLLTYFIMTFSTFLVFKL 220
Cdd:PRK08668 267 gVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFagglFHVFNHALFKGLFFLIFAA 346

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 992329291 221 ----NNTTNINTLATSWTKTPtLTALTPLVLLSLGGLPPLT-GFMPKWLILQEL 269
Cdd:PRK08668 347 viyrTGTTKISEMGGLIEKMP-FTFAMYLVAIISLAGIPPMsGFASKWLIFEAL 399
PRK12650 PRK12650
DUF4040 family protein;
110-189 5.72e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.49  E-value: 5.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 110 PTHAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHPT---NPT---LLILLGLTSTLVGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK12650 226 PFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVfhdVAVwnwLLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305


                 ....*.
gi 992329291 184 AHLGWM 189
Cdd:PRK12650 306 SQLGWI 311
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 112-193 8.31e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 38.02  E-value: 8.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 112 HAWLPEVLQGLDLTTGLILSTWQKLAPFTLLMQIHP----TNPTLLIL--LGLTSTLVGGWGGLNQTQLRKILAYSSIAH 185
Cdd:MTH00032 245 HTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPlfekAPLTLLIItiFGALTAFFAATVGLVQNDLKKVIAYSTCSQ 324


                 ....*...
gi 992329291 186 LGWMTLIM 193
Cdd:MTH00032 325 LGYMVLII 332
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-191 9.25e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 37.72  E-value: 9.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 992329291 100 LALALKIGLAPTHAWLPE-----------VLQGLDLTTG---LILSTWqklapfTLLMQIHPTNPTLLILLGLTSTLVGG 165
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQahveapvagsvILAGVLLKLGgygFIRFSW------PLLPEASEYFSPLIQTLSLLAIIYGS 287

                         90       100
                 ....*....|....*....|....*.
gi 992329291 166 WGGLNQTQLRKILAYSSIAHLGWMTL 191
Cdd:MTH00217 288 LTTCRQVDLKRIIAYSSVAHMGLVTL 313
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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