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Conserved domains on  [gi|1778128261|ref|YP_009710873|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Eleginus gracilis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.74e-75

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 223.09  E-value: 1.74e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261   1 MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261  81 AWGEWSVLGSVLGYLLLVLGAGSWFWGGWYEGMWVPVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1778128261 161 LTRGLARGALRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.74e-75

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 223.09  E-value: 1.74e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261   1 MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261  81 AWGEWSVLGSVLGYLLLVLGAGSWFWGGWYEGMWVPVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1778128261 161 LTRGLARGALRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-118 5.68e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 43.65  E-value: 5.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261  17 ISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAAL-AAEPYPEAWGEWSVLGSVLGYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100
                  ....*....|....*....|...
gi 1778128261  96 LLVLGAGSWFWGGWYEGMWVPVD 118
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAA 103
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.74e-75

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 223.09  E-value: 1.74e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261   1 MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261  81 AWGEWSVLGSVLGYLLLVLGAGSWFWGGWYEGMWVPVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1778128261 161 LTRGLARGALRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 4.62e-49

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 156.16  E-value: 4.62e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261   1 MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261  81 AWGEWSVLGsVLGYLLLVLGAGSWFWGGWYEGMWVPVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVLE 160
Cdd:MTH00065   81 AWGSWSVLV-YVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                         170
                  ....*....|...
gi 1778128261 161 LTRGLARGALRAV 173
Cdd:MTH00065  160 VTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 4.70e-37

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 125.63  E-value: 4.70e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261   1 MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261  81 AWGEWSVLGSVLGYLLLVLGAGSWFWGGW-YEGMWVPVDELIEFSVVAADSGGVALMYSLGGGLLVVSAWVLLLTLLVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWgMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1778128261 160 ELTRGLARGALRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-149 6.81e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 104.88  E-value: 6.81e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261   1 MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1778128261  81 AWG-EWSVLGSVLGYLLLVLGAGSWFWGGWYEGMWVPVD--------ELIEFSVVAADSGGVALMYSLGGGLLVVSAW 149
Cdd:MTH00109   82 TWVsNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGW 159
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 4.79e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 102.37  E-value: 4.79e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261   1 MAYIMLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261  81 AWGEWSVLGSVLGYLLLVLGAGSWFWGGWYEGMWVPVDELIEFSVvaadsGGVALMYSLGGGLLVVSAWVLLLTLLVVLE 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDL-----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 1778128261 161 LTRGLARGALRAV 173
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 8-79 1.90e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 66.85  E-value: 1.90e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1778128261   8 LLVGMVLGVISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPYP 79
Cdd:MTH00045    6 FLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-118 5.68e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 43.65  E-value: 5.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128261  17 ISVASNPSPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAAL-AAEPYPEAWGEWSVLGSVLGYL 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100
                  ....*....|....*....|...
gi 1778128261  96 LLVLGAGSWFWGGWYEGMWVPVD 118
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAA 103
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 5-74 6.60e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 38.33  E-value: 6.60e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1778128261   5 MLTLLVGMVLGVISVASNPSPYFAALGLVLVAGVGCV-VLMGH-GGSFLSLVLFLIYLGGMLVVFAYCAALA 74
Cdd:MTH00152    1 MSLMILLSVCFSLFLLLPLSKQPLSLGLVLLLLSLFVcVEIGLtLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 49-74 1.54e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 37.09  E-value: 1.54e-03
                          10        20
                  ....*....|....*....|....*.
gi 1778128261  49 SFLSLVLFLIYLGGMLVVFAYCAALA 74
Cdd:MTH00166   46 FWFSYILFLIFLGGMLVLFIYITSLA 71
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 4-78 4.67e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 35.75  E-value: 4.67e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1778128261   4 IMLTLLVGMVLGVISVASnpsPYFAALGLVLVAGVGCVVLMGHGGSFLSLVLFLIYLGGMLVVFAYCAALAAEPY 78
Cdd:MTH00212    5 LLLSLLLLLMLLFPLSAH---PLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEH 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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