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Conserved domains on  [gi|1904805240|ref|YP_009918233|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Hirundo smithii]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 5.29e-50

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 158.77  E-value: 5.29e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240   1 MMKFVLFLSLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  81 AWADLGVVGYVLG-LGLVIVVGSVSSGVFEVLVDGGTVNSGGLASFRLDFSGVALFYSWGVGLFLVGGWGLLLTLFVVLE 159
Cdd:MTH00138   81 SWGSWSVLGYVVGyLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1904805240 160 LVRGLSRGAIRAV 172
Cdd:MTH00138  161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 5.29e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 158.77  E-value: 5.29e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240   1 MMKFVLFLSLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  81 AWADLGVVGYVLG-LGLVIVVGSVSSGVFEVLVDGGTVNSGGLASFRLDFSGVALFYSWGVGLFLVGGWGLLLTLFVVLE 159
Cdd:MTH00138   81 SWGSWSVLGYVVGyLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1904805240 160 LVRGLSRGAIRAV 172
Cdd:MTH00138  161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 3.18e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.18e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  17 LAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSL-AADPYPEAWADLGVVGYVL-GL 94
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLlGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1904805240  95 GLVIVVGSVSSGVFEVLVDGGTVNSGGlasfRLDFSGVALFYSWgVGLFLVGGWGLLLTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 5.29e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 158.77  E-value: 5.29e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240   1 MMKFVLFLSLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  81 AWADLGVVGYVLG-LGLVIVVGSVSSGVFEVLVDGGTVNSGGLASFRLDFSGVALFYSWGVGLFLVGGWGLLLTLFVVLE 159
Cdd:MTH00138   81 SWGSWSVLGYVVGyLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1904805240 160 LVRGLSRGAIRAV 172
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.19e-49

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 157.60  E-value: 1.19e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240   1 MMKFVLFLSLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  81 AWADLGVVGYVLGLGLVIVVGSVSSGVF--EVLVDGGTVNSGGLASFRLDFSGVALFYSWGVGLFLVGGWGLLLTLFVVL 158
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLwgMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1904805240 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 7.51e-49

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 155.78  E-value: 7.51e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240   1 MMKFVLFLSLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  81 AWADLGVVGYVLGLGLVIVVGSVSSGVFEVLVDGGTVNSGGLASFRLDFSGVALFYSWGVGLFLVGGWGLLLTLFVVLEL 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                         170
                  ....*....|..
gi 1904805240 161 VRGLSRGAIRAV 172
Cdd:MTH00065  161 TRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-163 2.33e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 100.65  E-value: 2.33e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240   1 MMKFVLFLSLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  81 AW---------------ADLGVVGYVLGLGLVIVVGSVSSGVFEVLVDGgtvnsGGLASFRLDFSGVALFYSWGVGLFLV 145
Cdd:MTH00109   82 TWvsnkvvlgalllgllMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDT-----GGSGFFSEDAMGVAALYSYGTWLVVV 156

                         170
                  ....*....|....*...
gi 1904805240 146 GGWGLLLTLFVVLELVRG 163
Cdd:MTH00109  157 TGWSLFIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 2.24e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 95.44  E-value: 2.24e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240   1 MMKFVLFLSLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  81 AWADLGVVGYVLGLGLVIVVGsvssGVFEVLVDGGTVNSGGLASFRLDFSGVALFYSWGVGLFLVGGWGLLLTLFVVLEL 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFV----GFYFYGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156

                         170
                  ....*....|..
gi 1904805240 161 VRGLSRGAIRAV 172
Cdd:MTH00214  157 VRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 2-171 2.76e-15

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 69.16  E-value: 2.76e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240   2 MKFVLFLsLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSLAADPYPea 81
Cdd:MTH00045    1 MVFYLFL-ILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP-- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  82 waDLGVVGYVLGLGLVIVVGSVSSgvFEVLVDggTVNSGGLASFRLDFSGVALFYSWGVGLFLVGGWGLLLTLFVVLELV 161
Cdd:MTH00045   78 --SVSNLGEVLVLSLLLSLWVFIS--FDNFLE--LSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVIS 151

                         170
                  ....*....|
gi 1904805240 162 RGLSRGAIRA 171
Cdd:MTH00045  152 FGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-160 3.18e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.18e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1904805240  17 LAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSL-AADPYPEAWADLGVVGYVL-GL 94
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLlGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1904805240  95 GLVIVVGSVSSGVFEVLVDGGTVNSGGlasfRLDFSGVALFYSWgVGLFLVGGWGLLLTLFVVLEL 160
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 1.85e-04

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 40.10  E-value: 1.85e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1904805240   7 FLSLCFVLGGLAVASNPSPYYGVLGLVVGSVAGCGWLVSLGVSFVSLVLVMVYLGGMLVVFVYSVSL 73
Cdd:MTH00021    1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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