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Conserved domains on  [gi|1935445266|ref|YP_009944891|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Chelonoidis abingdonii]

Protein Classification

NADH-ubiquinone oxidoreductase subunit 4L( domain architecture ID 10009576)

NADH-ubiquinone oxidoreductase subunit 4L (ND4L) is core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.17e-43

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177185  Cd Length: 98  Bit Score: 137.02  E-value: 1.17e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  1 MTPTHFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVA 80
Cdd:MTH00126   1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                         90
                 ....*....|....*...
gi 1935445266 81 SSRTHGSDRLQNLNLLQC 98
Cdd:MTH00126  81 TARTHGTDRLQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.17e-43

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 137.02  E-value: 1.17e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  1 MTPTHFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVA 80
Cdd:MTH00126   1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                         90
                 ....*....|....*...
gi 1935445266 81 SSRTHGSDRLQNLNLLQC 98
Cdd:MTH00126  81 TARTHGTDRLQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
11-98 3.23e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 59.50  E-value: 3.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266 11 AFIISITGLsLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVASSRTHGSDRL 90
Cdd:pfam00420  9 LFLIGLYGL-LLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDV 87


                 ....*...
gi 1935445266 91 QNLNLLQC 98
Cdd:pfam00420 88 DSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.17e-43

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 137.02  E-value: 1.17e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  1 MTPTHFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVA 80
Cdd:MTH00126   1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                         90
                 ....*....|....*...
gi 1935445266 81 SSRTHGSDRLQNLNLLQC 98
Cdd:MTH00126  81 TARTHGTDRLQNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 7.20e-39

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 124.96  E-value: 7.20e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  1 MTPTHFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVA 80
Cdd:MTH00125   1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                         90
                 ....*....|....*...
gi 1935445266 81 SSRTHGSDRLQNLNLLQC 98
Cdd:MTH00125  81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 7.44e-39

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 124.72  E-value: 7.44e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  1 MTPTHFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVA 80
Cdd:MTH00067   1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVA 80

                         90
                 ....*....|....*...
gi 1935445266 81 SSRTHGSDRLQNLNLLQC 98
Cdd:MTH00067  81 TTRTHGTDHLKNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 6.17e-26

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 91.92  E-value: 6.17e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  1 MTPTHFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVA 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1935445266 81 SSRTHGSDRLQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 4-96 9.44e-19

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 73.82  E-value: 9.44e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  4 THFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVASSR 83
Cdd:MTH00181   1 MMFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNR 80

                         90
                 ....*....|...
gi 1935445266 84 THGSDRLQNLNLL 96
Cdd:MTH00181  81 THGSDHLLKFNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 1.37e-14

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 63.40  E-value: 1.37e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  1 MTPTHFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVA 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 1935445266 81 SSRTHGSDRLQNLNLLQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
11-98 3.23e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 59.50  E-value: 3.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266 11 AFIISITGLsLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVASSRTHGSDRL 90
Cdd:pfam00420  9 LFLIGLYGL-LLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYRTHGTDDV 87


                 ....*...
gi 1935445266 91 QNLNLLQC 98
Cdd:pfam00420 88 DSLNLLKG 95
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 6-98 3.91e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 54.21  E-value: 3.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  6 FSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLtpMLMLSFSACEAGMGLSLLVASSRTH 85
Cdd:MTH00188   7 LVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLS--LVLLTFAACEASVGLALLVSLIRSH 84

                         90
                 ....*....|...
gi 1935445266 86 GSDRLQNLNLLQC 98
Cdd:MTH00188  85 GSDYVSSLNLIKC 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 12-92 8.72e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 45.53  E-value: 8.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLtpMLMLSFSACEAGMGLSLLVASSRTHGSDRLQ 91
Cdd:MTH00162  11 FFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFL--LFFLTFSVCEGALGLSILVSMIRSHGNDYFS 88


                 .
gi 1935445266 92 N 92
Cdd:MTH00162  89 S 89
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 12-98 2.77e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 44.45  E-value: 2.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFItlSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVASSRTHGSDRLQ 91
Cdd:MTH00149  13 FLMGVFALLFQYKHLLSILLSLEALMLSLLV--MMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGNDYVS 90


                 ....*..
gi 1935445266 92 NLNLLQC 98
Cdd:MTH00149  91 SLSSLKF 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 1-98 3.26e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 44.36  E-value: 3.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266  1 MTPTHFSCYSAFIISITGLSLHRTHLVSTLLCLEGMMLSLFItLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVA 80
Cdd:MTH00013   1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLAL-FIPLSLMFANQVNGMLAIVLLTFGACEASLGLSLLVL 79

                         90
                 ....*....|....*...
gi 1935445266 81 SSRTHGSDRLQNLNLLQC 98
Cdd:MTH00013  80 MTRSYGNDMLKSLTSNKC 97
ND4L MTH00180
NADH dehydrogenase subunit 4L; Provisional
 12-97 9.03e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177231  Cd Length: 99  Bit Score: 38.09  E-value: 9.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVASSRTHGSDRLQ 91
Cdd:MTH00180  13 FILGVLGIVLNRSNLIIMLMSIELMLLAISLLFLINSVAIDNLIGQIFTIMILTVAAAESAIGLAILVAYYRIRGTIAVK 92


                 ....*.
gi 1935445266 92 NLNLLQ 97
Cdd:MTH00180  93 SLNLLR 98
ND4L MTH00001
NADH dehydrogenase subunit 4L; Provisional
 12-97 5.21e-04

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177099  Cd Length: 99  Bit Score: 35.81  E-value: 5.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1935445266 12 FIISITGLSLHRTHLVSTLLCLEGMMLSLFITLSMWPIQLQISSFMLTPMLMLSFSACEAGMGLSLLVASSRTHGSDRLQ 91
Cdd:MTH00001  13 FLLGIWGIILNRGHFIIMLVSIELVLLSTFFLFLINSIEIDLLIEQIFTIMGLTIAAAESAIGLAIMVAYYRIRGTISLK 92


                 ....*.
gi 1935445266 92 NLNLLQ 97
Cdd:MTH00001  93 SLNSLR 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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