NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1998563282|ref|YP_010000457|]
View 

NADH dehydrogenase subunit 2 (mitochondrion) [Vidua macroura]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
1-346 2.15e-162

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 457.36  E-value: 2.15e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 TGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSSLLVLMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320
                         330       340
                  ....*....|....*....|....*.
gi 1998563282 321 VNILVAILVTMSIILLPISPMILSIP 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
1-346 2.15e-162

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 457.36  E-value: 2.15e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 TGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSSLLVLMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320
                         330       340
                  ....*....|....*....|....*.
gi 1998563282 321 VNILVAILVTMSIILLPISPMILSIP 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
23-268 9.17e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 87.75  E-value: 9.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  23 SNHWVMAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  91 HPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM-KLPPIAL-----LFMTAQSLNSSLLVLMAILSAAV 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 165 GGWMGLNQTQVRKILAFSSISHLGWM--AIIITYYPKLTLLNFYL--YAVMTTAVFLALNS-----MKALSLPTLMTAWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMliALGAGTIYGIQAAIFHLltHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1998563282 236 KTPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
8-298 1.54e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 86.32  E-value: 1.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   8 VFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQAAASALVLF-SSMTNAWhTGQWD 85
Cdd:COG1007   106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLN 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  86 ITQLTHPVSS-----------LVLT-SAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALL-------FMTA 146
Cdd:COG1007   185 LAGIAAALAAgganspllllgLVLVlAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveaFPGL 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 147 QSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTL--LNFYL--YAVMTTAVFLALNSM 222
Cdd:COG1007   265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVILLL 344
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 223 K-----ALSLPTLMTAWTKTPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLA 297
Cdd:COG1007   345 SrkggeAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVV 424

                  .
gi 1998563282 298 Y 298
Cdd:COG1007   425 K 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
14-297 4.37e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.00  E-value: 4.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  14 LLGTTITLSSNHWVMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  93 VSSLVLT------------SAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIAL---LFMTAQS----LNSSL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVflrLFLYILFgfseAWQIF 271
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 154 LVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGW--MAIIITYYPKLTLLNFYL--YAVMTTAVFLALNSMKALSLP- 228
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYilIGLLAGTLEGIKAVLFYIfiYALMSLGAFGVLSLLRSYKDEw 351
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1998563282 229 ----TLMTAWTKT-PSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLA 297
Cdd:TIGR01770 352 ieyiSDFAGLFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
1-346 2.15e-162

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 457.36  E-value: 2.15e-162
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWH 80
Cdd:MTH00112    1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 TGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSSLLVLMAIL 160
Cdd:MTH00112   81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00112  161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00112  241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320
                         330       340
                  ....*....|....*....|....*.
gi 1998563282 321 VNILVAILVTMSIILLPISPMILSIP 346
Cdd:MTH00112  321 KNTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
1-345 3.53e-129

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 372.99  E-value: 3.53e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWH 80
Cdd:MTH00135    1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 TGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSlNSSLLVLMAIL 160
Cdd:MTH00135   81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00135  160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00135  240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319
                         330       340
                  ....*....|....*....|....*.
gi 1998563282 321 VNIL-VAILVTMSIILLPISPMILSI 345
Cdd:MTH00135  320 QLTLpLAISTTATLMLLPLTPAILAL 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
1-345 1.75e-128

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 371.18  E-value: 1.75e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWH 80
Cdd:MTH00070    1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 TGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSSLLVLMAIL 160
Cdd:MTH00070   81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00070  161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00070  241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320
                         330       340
                  ....*....|....*....|....*
gi 1998563282 321 VNILVAILVTMSIILLPISPMILSI 345
Cdd:MTH00070  321 TNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
1-345 5.28e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 326.80  E-value: 5.28e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWH 80
Cdd:MTH00105    1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 TGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSSLLVLMAIL 160
Cdd:MTH00105   81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00105  161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00105  241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320
                         330       340
                  ....*....|....*....|....*.
gi 1998563282 321 -VNILVAILVTMSIILLPISPMILSI 345
Cdd:MTH00105  321 kPMTLLPTLIILSTMLLPLTPMLSIL 346
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
1-346 2.67e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 281.86  E-value: 2.67e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWH 80
Cdd:MTH00200    1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 TGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSSLLVLMAIL 160
Cdd:MTH00200   81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00200  161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00200  241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320
                         330       340
                  ....*....|....*....|....*.
gi 1998563282 321 VNILVAILVTMSIILLPISPMILSIP 346
Cdd:MTH00200  321 SNLLVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
1-346 7.81e-78

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 242.14  E-value: 7.81e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWH 80
Cdd:MTH00041    1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 TGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSSLLVLMAIL 160
Cdd:MTH00041   81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00041  161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00041  241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320
                         330       340
                  ....*....|....*....|....*....
gi 1998563282 321 VNIL---VAILVTMSIILLPISPMILSIP 346
Cdd:MTH00041  321 ITVYgviLSILSSISILGLLLIPLFLSFL 349
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
1-345 2.52e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 175.78  E-value: 2.52e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   1 MNPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWh 80
Cdd:MTH00160    2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  81 tgqwdITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTaqsLNSSLLVLMAIL 160
Cdd:MTH00160   81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 161 SAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSL 240
Cdd:MTH00160  153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 241 SAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYcTAITLPPHTTNQIKQWRINKP 320
Cdd:MTH00160  233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISY-SSLMLNYNKNKWNLKKKKNKF 311
                         330       340
                  ....*....|....*....|....*
gi 1998563282 321 VNILVaILVTMSIILLPISPMILSI 345
Cdd:MTH00160  312 SLILN-FLSFISLFGLILSSLLFLL 335
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
7-310 1.31e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 158.40  E-value: 1.31e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   7 LVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSmtnawhTGQWDI 86
Cdd:MTH00011    9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSF 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  87 TQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSSLLVLMAILSAAVGG 166
Cdd:MTH00011   83 PSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 167 WMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSLSAMLLL 246
Cdd:MTH00011  163 LGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFI 242
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1998563282 247 TLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYcTAITLPPHTTN 310
Cdd:MTH00011  243 MLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
5-339 2.59e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 154.66  E-value: 2.59e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   5 AKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQW 84
Cdd:MTH00144    5 SNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  85 DitqlthpvSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLN-SSLLVLMAILSAA 163
Cdd:MTH00144   85 F--------SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlAYLLCVISVLSAL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 164 VGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLpTLMTAWTKTPSLSAM 243
Cdd:MTH00144  157 VGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSM-KDLGSLKPSYKTGLS 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 244 LLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAITLpphtTNQIKQWRINKPVNI 323
Cdd:MTH00144  236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSS----SKSKKSNSSKVLNSS 311
                         330
                  ....*....|....*.
gi 1998563282 324 LVAILVTMSIILLPIS 339
Cdd:MTH00144  312 IISLNLLGGLLFLLLY 327
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
8-342 5.04e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 135.57  E-value: 5.04e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   8 VFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTgqwdit 87
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL------ 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  88 qLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLfmTAQSLNSSLLVLMAILSAAVGGW 167
Cdd:MTH00197   76 -YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGGI 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 168 MGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAVMTTAVFLALNSMKALSLPTLMTAWTKTPSLSAMLLLT 247
Cdd:MTH00197  153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 248 LLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAYCTAItlppHTTNQIKQWRINKPVNILVAI 327
Cdd:MTH00197  233 FLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLI----LSNWMINFLMKINLLYSGLFI 308
                         330
                  ....*....|....*
gi 1998563282 328 LVTMSIILLPISPMI 342
Cdd:MTH00197  309 LLMMMLPLLMIFTMI 323
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
23-268 9.17e-20

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 87.75  E-value: 9.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  23 SNHWVMAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWDITQL-----------T 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  91 HPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM-KLPPIAL-----LFMTAQSLNSSLLVLMAILSAAV 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLvKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 165 GGWMGLNQTQVRKILAFSSISHLGWM--AIIITYYPKLTLLNFYL--YAVMTTAVFLALNS-----MKALSLPTLMTAWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMliALGAGTIYGIQAAIFHLltHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1998563282 236 KTPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
8-298 1.54e-18

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 86.32  E-value: 1.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   8 VFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQAAASALVLF-SSMTNAWhTGQWD 85
Cdd:COG1007   106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLN 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  86 ITQLTHPVSS-----------LVLT-SAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALL-------FMTA 146
Cdd:COG1007   185 LAGIAAALAAgganspllllgLVLVlAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALlrllveaFPGL 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 147 QSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTL--LNFYL--YAVMTTAVFLALNSM 222
Cdd:COG1007   265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAVILLL 344
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 223 K-----ALSLPTLMTAWTKTPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLA 297
Cdd:COG1007   345 SrkggeAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVV 424

                  .
gi 1998563282 298 Y 298
Cdd:COG1007   425 K 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
13-267 3.88e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 84.31  E-value: 3.88e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  13 LLLGTTITLSSNHWVMAWTGLEINTLAILPLI-SKSHHPRAIEAATKYFLVQAAASALVLFS-------------SMTNA 78
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  79 WHTGQWDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTaqSLNSSLLVLMA 158
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSI--GLNVNILLIGG 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 159 ILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYP----KLTLLNFYLYAVMTTAVF---LALNSMKALsLPTLM 231
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFsiiLALNVYKNL-IIEFS 238
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1998563282 232 TAWTKTPSLSAMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00196  239 GLSRRLPILAITLALTFLSIAGIPPLVGFLGKWLIL 274
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
14-297 4.37e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 85.00  E-value: 4.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  14 LLGTTITLSSNHWVMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWDITQLTHP 92
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  93 VSSLVLT------------SAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIAL---LFMTAQS----LNSSL 153
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVflrLFLYILFgfseAWQIF 271
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 154 LVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGW--MAIIITYYPKLTLLNFYL--YAVMTTAVFLALNSMKALSLP- 228
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYilIGLLAGTLEGIKAVLFYIfiYALMSLGAFGVLSLLRSYKDEw 351
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1998563282 229 ----TLMTAWTKT-PSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLA 297
Cdd:TIGR01770 352 ieyiSDFAGLFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-296 1.50e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 83.33  E-value: 1.50e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   8 VFTLSLL--LGTTITLSSNHWVMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQW 84
Cdd:PRK05777  105 FYLLVLFalLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSL 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  85 DITQLTHPVSS------------LVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALL-------FMT 145
Cdd:PRK05777  185 SFAGIAKALADgsgnsllllfglVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllvvaFGG 264
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 146 AQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWM--AIIITYYPKLTLLNFYL--YAVMTTAVFLALNS 221
Cdd:PRK05777  265 LSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvGLAAGTAEGYSAVLFYLlaYLFMTLGAFGVISL 344
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 222 MK-----ALSLPTLMTAWTKTPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRL 296
Cdd:PRK05777  345 LRrkggeAESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
8-267 1.62e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 80.06  E-value: 1.62e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   8 VFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLIS-KSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWDI 86
Cdd:MTH00199  101 ILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSI 180
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  87 ----TQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNssLLVLMAILSA 162
Cdd:MTH00199  181 qginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICAVLSI 258
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 163 AVGGWMGLNQTQVRKILAFSSISHLGW----MAIIITYYPKLTLLNFYLYAVMTTAVF---LALNSMKALsLPTLMTAWT 235
Cdd:MTH00199  259 IYGAIGALNQTKIKRLLAYSGIGHMGFilfgVAIGSFESIQASLIYMIIYVIMSICSFsiiLSLKLTKGL-IVEVSGLSR 337
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1998563282 236 KTPSLSAMLLLTLLSLAGLPPLTGFLPKWLII 267
Cdd:MTH00199  338 KNPVIALTLALTFLSIAGIPPLAGFLSKWLIL 369
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
3-210 7.63e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 69.50  E-value: 7.63e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   3 PQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAI---------EAATKYFLVQAAASALVLFS 73
Cdd:MTH00198  187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFG 266
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  74 SMTNAWHTGQ--------------WDITQLTHPVSSLVLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLppI 139
Cdd:MTH00198  267 CALYFGFTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--T 344
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1998563282 140 ALLFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLYAV 210
Cdd:MTH00198  345 VYILLTSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAV 415
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
9-282 1.65e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 67.86  E-value: 1.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   9 FTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWDITQ 88
Cdd:COG0651   112 LFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMAD 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  89 LTHPVSSL----------VLTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLM-KLPPIAL-----LFMTAQSLN-- 150
Cdd:COG0651   192 LAARLAELdpglllaafaLLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLtKVGVYAIlrvltLLFGADPALfl 271
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 151 SSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYYPKLTLLNFYLY----AVMTTAVFLA----LNSM 222
Cdd:COG0651   272 GTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHllnhALAKALLFLAagaiERAT 351
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 223 KALSLPTLMTAWTKTPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATII 282
Cdd:COG0651   352 GTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVL 411
ndhB CHL00049
NADH dehydrogenase subunit 2
7-208 6.69e-09

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 56.94  E-value: 6.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   7 LVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHP-RAIEAATKYFLVQAAASALVL--FSSM--TNAWHT 81
Cdd:CHL00049  114 LLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVygFSWLygLSGGEI 193
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  82 GQWDI------TQLTHPVSSLV----LTSAIAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIAL-------LFM 144
Cdd:CHL00049  194 ELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALatrifdiPFY 273
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1998563282 145 TAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAI-IIT------YYPKLTLLNFYLY 208
Cdd:CHL00049  274 FSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIgIIVgdsndgYASMITYMLFYIF 344
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
291-340 2.92e-08

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 49.56  E-value: 2.92e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1998563282 291 FFYLRLAYCTAITLPPHTTNQIKQWRINKPVNI-LVAILVTMSIILLPISP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTlLLPTLTTLSILLLPLTP 51
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-192 1.96e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 52.36  E-value: 1.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  50 PRAIEAATKYFLVQAAASALVLF-SSMTNAWHTGQwdiTQLTH----------PVSSLVLT---SAIAMKLGLVPFHFWF 115
Cdd:PRK02504  157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGS---TQLSAialalitspsLGLALALVfviAGIAFKISAVPFHQWT 233
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 116 PEVMQGSSLLTGLLLSTLMKLPPIAL---LFMTAQSLNSS----LLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLG 188
Cdd:PRK02504  234 PDVYEGSPTPVVAFLSVGSKAAGFALairLLVTAFPSFDEqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAG 313

                  ....
gi 1998563282 189 WMAI 192
Cdd:PRK02504  314 FVMI 317
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
33-266 7.70e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 50.48  E-value: 7.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  33 LEINTLAILPLIS-KSHHPRAIEAATKYFLVQAAASALVLFS---------SMTNAWHTGQWDITQLTHPVSSLVL-TSA 101
Cdd:PRK08376  150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENPTVVAKIALALfIAG 229
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 102 IAMKLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIAL------LFMTAQSLNSS--LLVLMAILSAAVGGWMGLNQT 173
Cdd:PRK08376  230 LAMKSGAVPVHMWLPDAYPAAPSSISAMLLVIKQAGLYALarvlfsIYGPAINLATVgwVIIILGCLTMFVGVAMAVVQK 309
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 174 QVRKILAFSSISHLGWM----AIIITYYpKLTLLNFYLYAVMTTAVFLALNS--MKAL---------------SLPTLMT 232
Cdd:PRK08376  310 DVKRLLAYHSVSQIGYMllglGVGLAAL-GDPAMASYGEIALAGGIYHIVNHalYKALlfltagaviyetgtrNLNELGG 388
                         250       260       270
                  ....*....|....*....|....*....|....
gi 1998563282 233 AWTKTPSLSAMLLLTLLSLAGLPPLTGFLPKWLI 266
Cdd:PRK08376  389 LARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
49-192 9.74e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 50.08  E-value: 9.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  49 HPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQW--DITQLTHPVSSLVLTSAI--------AMKLGLVPFHFWFPEV 118
Cdd:COG1008   156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPLPLTAQLLLflaffiafAVKVPMFPFHTWLPDA 235
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 119 -MQGSSLLTGLLLSTLMKLPPIAL------LFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMA 191
Cdd:COG1008   236 hVEAPTAGSVLLAGVLLKMGGYGLlrfalpLFPEASAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVL 315

                  .
gi 1998563282 192 I 192
Cdd:COG1008   316 L 316
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
50-194 2.20e-06

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 49.17  E-value: 2.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  50 PRAIEAATKYFLVQAAASALVLFSSMTNAW-HTGQWDITQL-THPVSSLVLT-------SAIAMKLGLVPFHFWFPEVM- 119
Cdd:TIGR01972 152 PNRIYAAMKFFLYTLAGSLLMLLAILGLYFlGGGTFDLLELlNLPLPFGVQTwlflaffIAFAVKVPLFPLHTWLPDAHv 231
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 120 QGSSLLTGLLLSTLMKLPPIAL------LFMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAII 193
Cdd:TIGR01972 232 EAPTAGSVILAGVLLKMGTYGFlrfnlpLFPDASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLG 311

                  .
gi 1998563282 194 I 194
Cdd:TIGR01972 312 I 312
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
13-194 5.53e-06

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 47.83  E-value: 5.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  13 LLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAA------SALVLFSSMTNAWHTGQWDI 86
Cdd:PRK08676  111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNW 190
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  87 TQLTHPVS----SLVLTSAIAM------KLGLVPFHFWFPEVMQGSSLLTGLLLSTLMK-------LPPIALLFMT-AQS 148
Cdd:PRK08676  191 TELAAHASllspSVLGASFLFIfigflaKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLnigiygiLRLSALLRQSgAAE 270
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1998563282 149 LNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 194
Cdd:PRK08676  271 QFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGI 316
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
2-275 1.73e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 43.45  E-value: 1.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   2 NPQAKLVFTLSLLLGTTITLSSNHWVMAWTGLEINTLAILPLISKSHHpRAIEAATKYFLVQAAASALVLFSSMTNAWHT 81
Cdd:PRK08668   96 NDAYFNMFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAIFLIYAKT 174
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  82 GQWDITQLTHPVSS-----------LVLTSAIAMKLGLVPFHFWFPEV------------------MQGSSLLTGLLLST 132
Cdd:PRK08668  175 GTFDFADISQGLINdtstgfalivfLFLLAFGVAKAGIFPLHVWAPDAyseapqsfsavlsgqlskLGAYGFLLVLYVLP 254
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 133 LMKLPPIALLFMTAQSLNSSLLVLMAIlSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIIITYypkLTLLNFY--LYAV 210
Cdd:PRK08668  255 GTKLFSEFGTYRGVPLFNYILAWLGNI-SIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGL---GTSLGFAggLFHV 330
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1998563282 211 MTTAVFLALN--SMKALSLPTLMTAWT-------KTPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQELTKQDM 275
Cdd:PRK08668  331 FNHALFKGLFflIFAAVIYRTGTTKISemgglieKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGM 404
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
55-190 2.78e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 42.76  E-value: 2.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  55 AATKYFLVQAAASALVLFSSMTNAWHTG--QWDITQL---THPVSS-LVLTSAI----AMKLGLVPFHFWFPEV-MQGSS 123
Cdd:PRK06473  158 AATKFLLYTAISGILILVSFLGLVWLSGasSFDYEPLrshTLPLSTqLLLLAPIlvgfGIKIPLVPFHTWLPDAhVEAST 237
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998563282 124 LLTGLLLSTLMKLPPIALL------FMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWM 190
Cdd:PRK06473  238 PVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
55-194 4.69e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 41.94  E-value: 4.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  55 AATKYFLVQAAASALVLFSSMTNAWHTGQ--WDITQLTHPVSSLVLT--------SAIAMKLGLVPFHFWFPEVM-QGSS 123
Cdd:PRK12561  138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAKSYPLALElllyagflIAFGVKLPIFPLHTWLPDAHgEASA 217
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1998563282 124 LLTGLLLSTLMKLPPIALLFMTAQSLN------SSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 194
Cdd:PRK12561  218 PVSMILAGVLLKMGGYALIRFNVQMLPdahvyfAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLLGI 294
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
9-192 9.13e-04

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 41.07  E-value: 9.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   9 FTLSLLLgttiTLSSNHWVMAWTGLEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSS----------MTNA 78
Cdd:PRK06458  117 FLFTMLL----ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTilvyanaatvMGDG 192
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  79 WHTGQW-DITQLTHPVSSLVLTSAIAM-------KLGLVPFHFWFPEVMQGSSLLTGLLLSTLmkLPPIALL------FM 144
Cdd:PRK06458  193 EMAILWtELLKHASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDAHSEAPSPVSALLSGV--LLNVALYavlryyIL 270
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1998563282 145 TAQSLNS----SLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAI 192
Cdd:PRK06458  271 IDAAIGSdfpgRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
7-190 9.83e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 40.91  E-value: 9.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   7 LVFTLSLLLgttITLSSNHWVMaWTGLEINTLAILPLISKSHH-PRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWD 85
Cdd:COG1009   118 LLFMAAMLG---LVLSDNLLLL-FVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLN 193
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  86 ITQLTHPVSSLVLTSAI----------AM-KLGLVPFHFWFPEVMQGSSlltglllstlmklPPIALL----------FM 144
Cdd:COG1009   194 FSELLAAAPTILSSPLLtlillllllgAFgKSAQFPLHFWLPDAMEGPT-------------PVSALLhaatmvkagvYL 260
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1998563282 145 TAQ-----SLNSSLLVLMAILSAA---VGGWMGLNQTQVRKILAFSSISHLGWM 190
Cdd:COG1009   261 LARlsplfALSPVWLTVVAIIGAItalFAALIALAQTDIKRVLAYSTVSQLGYM 314
PRK12650 PRK12650
DUF4040 family protein;
9-194 1.17e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 40.80  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282   9 FTLSLLLgttITLSSNHWVM--AWtglEINTLAILPLISKSHhPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWDI 86
Cdd:PRK12650  119 FMAAMLL---LVLADDVVVLfvAW---ELVSLASFFLIARSG-SGGEAGSIRTLILTFFGGLTLLAAVAIAATQTGTTSL 191
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  87 TQLTHPVS---SLVLTSAIAM--------KLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALL--FMTAQSLN--- 150
Cdd:PRK12650  192 SGILHSDVwaeKPGLTTVVAVliavaaftKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLlrFSPVFHDVavw 271
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1998563282 151 SSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 194
Cdd:PRK12650  272 NWLLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATI 315
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
80-194 1.33e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 40.68  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  80 HTGQWDITQL-THPVSSLVLTSAIAM-------KLGLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNS 151
Cdd:PRK12644  183 AAGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVARLAPGFAD 262
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1998563282 152 S-----LLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWMAIII 194
Cdd:PRK12644  263 VpvwrpTVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
50-194 1.71e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 40.19  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  50 PRAIEAATKYFLVQAAASALVLFSSMTNAWH----TGQWDITQL-THPVSSLVLTS-------AIAMKLGLVPFHFWFPE 117
Cdd:PRK05846  157 KNRIYAATKFFLYTLLGSLLMLVAIIYLVVVyynaTGTFDIADLlNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPD 236
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 118 VM-QGSSLLTGLLLSTLMKLPPIALL------FMTAQSLNSSLLVLMAILSAAVGGWMGLNQTQVRKILAFSSISHLGWM 190
Cdd:PRK05846  237 AHvQAPTAGSVLLAGILLKMGAYGLLrfslplFPDASHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFV 316

                  ....
gi 1998563282 191 AIII 194
Cdd:PRK05846  317 TLGI 320
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
33-298 2.21e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 39.86  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  33 LEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFS-SMTNAwHTGQWDITQLTH--PVSSLVLT------SAIA 103
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGvGLLYG-VTGTLNMADLAGalAENPTVVTafgfvlLALA 213
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 104 MKLGLVPFHFWFPEVMQGSSLLTGLLLS-TLMKLPPIALL----------FMTAQSLNSSLLVLmAILSAAVGGWMGLNQ 172
Cdd:PRK08375  214 LKAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIriyftvfggdFRFALGLGWLLAVL-ALLSMLVGSLAALGQ 292
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 173 TQVRKILAFSSISHLGWMAIIITYYPKLTLLN--FYL--YAVMTTAVFLA------------LNSMKAL--SLPTLMTAW 234
Cdd:PRK08375  293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLAagaievtygtrrLSELSGLgrRMPLTAAAF 372
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1998563282 235 TktpslsamllLTLLSLAGLPPLTGFLPKWLIIQELTKQDMAPAATIISLLSLLSLFFYLRLAY 298
Cdd:PRK08375  373 A----------VASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
92-268 2.36e-03

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 39.55  E-value: 2.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  92 PVSSLVLTSAIAMKLGLVPFhFWFPEVMQGSSLLTGLLLSTLMKLPPI-------ALLFMTAQSLNSSLLVLMAILSAAV 164
Cdd:PRK12663  207 TTIALLFLLAFGMKAALFPF-MWLPAAYHTPNTEVAALFAALLTKVGIyalirvfTLLFPQERELLHPLLATMAAITMVI 285
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 165 GGWMGLNQTQVRKILAFSSISHLGWM--AIIITYYPKLTLLNFYLYAVMT--TAVFLALNSMKAL----SLPTLMTAWTK 236
Cdd:PRK12663  286 GALGALAYKDIRRIAGYQVISSIGFIllGLALGTPAGINGAIFYLVHDMVvkTALFLIAGSLVRLtgyrSLQYLGGLYRK 365
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1998563282 237 TPSLSAMLLLTLLSLAGLPPLTGFLPKWLIIQ 268
Cdd:PRK12663  366 EPLFGALFLILIFAIGGLPPFSGFWGKVLLVQ 397
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
33-196 9.08e-03

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 37.65  E-value: 9.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282  33 LEINTLAILPLISKSHHPRAIEAATKYFLVQAAASALVLFSSMTNAWHTGQWDIT---QLTHPVSSLV---LTSAIAMKL 106
Cdd:PRK06525  142 FEITGLCSWALISYYQSPKALRSALKALLITHIGSLGLYLAAATLFLQTGTFALSalsGLHGSLKYLVflgILFAAWGKS 221
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998563282 107 GLVPFHFWFPEVMQGSSLLTGLLLSTLMKLPPIALLFMTAQSLNSS------LLVLMAILSAAVGGWMGLNQTQVRKILA 180
Cdd:PRK06525  222 AQLPFYSWLPDAMEAPTPASAYLHAASMVKVGVYIFARAIQSMGPIphvigyVGAVMAIVTLLYGFLMYLPQQDMKRLLA 301
                         170
                  ....*....|....*.
gi 1998563282 181 FSSISHLGWMAIIITY 196
Cdd:PRK06525  302 YSTITQLGYMFFGLSL 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH
HHS Vulnerability Disclosure