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Conserved domains on  [gi|2018133005|ref|YP_010037178|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Galictis vittata]

Protein Classification

NADH-ubiquinone oxidoreductase chain 4L( domain architecture ID 10009568)

NADH-ubiquinone oxidoreductase chain 4L is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) and is believed to belong to the minimal assembly required for catalysis; Complex I functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.40e-40

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177169  Cd Length: 98  Bit Score: 129.28  E-value: 1.40e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  1 MSAVYINILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 2018133005 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.40e-40

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 129.28  E-value: 1.40e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  1 MSAVYINILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 2018133005 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 9.99e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 58.34  E-value: 9.99e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  3 AVYINILLAFTLSLMGLLiYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLL-LRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 2018133005 83 NTYGTDYVQNLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.40e-40

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 129.28  E-value: 1.40e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  1 MSAVYINILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVM 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 2018133005 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 1-98 6.77e-27

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 94.65  E-value: 6.77e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  1 MSAVYINILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVM 80
Cdd:MTH00126   1 MTPVHFSFSSAFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVA 80

                         90
                 ....*....|....*...
gi 2018133005 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00126  81 TARTHGTDRLQNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 8.96e-24

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 86.44  E-value: 8.96e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  1 MSAVYINILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVM 80
Cdd:MTH00125   1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                         90
                 ....*....|....*...
gi 2018133005 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00125  81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 3.19e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 80.03  E-value: 3.19e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  1 MSAVYINILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVM 80
Cdd:MTH00067   1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVA 80

                         90
                 ....*....|....*...
gi 2018133005 81 VSNTYGTDYVQNLNLLQC 98
Cdd:MTH00067  81 TTRTHGTDHLKNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 9-96 1.45e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 60.34  E-value: 1.45e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  9 LLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVMVSNTYGTD 88
Cdd:MTH00181   6 ISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSD 85


                 ....*...
gi 2018133005 89 YVQNLNLL 96
Cdd:MTH00181  86 HLLKFNLL 93
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
3-98 9.99e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 58.34  E-value: 9.99e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  3 AVYINILLAFTLSLMGLLiYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVMVS 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLL-LRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 2018133005 83 NTYGTDYVQNLNLLQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 1.34e-10

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 53.00  E-value: 1.34e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  1 MSAVYINILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVM 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 2018133005 81 VSNTYGTDYVQNLNLLQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 9-98 2.37e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 47.15  E-value: 2.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  9 LLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTIltNHFTLANMAPIILLVFAACEAVLGLSLLVMVSNTYGTD 88
Cdd:MTH00149  10 LFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSS--GLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGND 87

                         90
                 ....*....|
gi 2018133005 89 YVQNLNLLQC 98
Cdd:MTH00149  88 YVSSLSSLKF 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 5-92 4.48e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 46.30  E-value: 4.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  5 YINILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSttILTNHFTLANMAPIILLVFAACEAVLGLSLLVMVSNT 84
Cdd:MTH00162   4 LLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLF--LYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                 ....*...
gi 2018133005 85 YGTDYVQN 92
Cdd:MTH00162  82 HGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 8-98 1.89e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 44.97  E-value: 1.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005  8 ILLAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLFVMMSTTILTNHFTLanMAPIILLVFAACEAVLGLSLLVMVSNTYGT 87
Cdd:MTH00188   9 ILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKEL--YLSLVLLTFAACEASVGLALLVSLIRSHGS 86

                         90
                 ....*....|.
gi 2018133005 88 DYVQNLNLLQC 98
Cdd:MTH00188  87 DYVSSLNLIKC 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 10-98 1.84e-06

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 42.43  E-value: 1.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2018133005 10 LAFTLSLMGLLIYRTHLMSSLLCLEGMMLSLfVMMSTTILTNHFTLANMAPIILLVFAACEAVLGLSLLVMVSNTYGTDY 89
Cdd:MTH00013  10 ISPFISMFNLSLQRKHLLMSLLSLEAMILSL-ALFIPLSLMFANQVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGNDM 88


                 ....*....
gi 2018133005 90 VQNLNLLQC 98
Cdd:MTH00013  89 LKSLTSNKC 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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