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Conserved domains on  [gi|2206977012|ref|YP_010296002|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Bagrus docmak]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-171 5.74e-61

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 186.50  E-value: 5.74e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012   1 MMYFFDLLLLSLVVGLVGVASNPAPYFAALGLAVAAGVGCGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012  81 TWGAGSVKVYVLMYLLGVGVALWWFWSEYGG--WIVVDEFKEFFMVRGDTGGVSLMYSVGGGMLITCAWVLLLCLFVVLE 158
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEgsWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2206977012 159 LTRGLSRGALRAV 171
Cdd:MTH00138  161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-171 5.74e-61

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 186.50  E-value: 5.74e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012   1 MMYFFDLLLLSLVVGLVGVASNPAPYFAALGLAVAAGVGCGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012  81 TWGAGSVKVYVLMYLLGVGVALWWFWSEYGG--WIVVDEFKEFFMVRGDTGGVSLMYSVGGGMLITCAWVLLLCLFVVLE 158
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEgsWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2206977012 159 LTRGLSRGALRAV 171
Cdd:MTH00138  161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
40-116 7.60e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 37.87  E-value: 7.60e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2206977012  40 CGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAAL-AAEPFPETWGAGSVKVYVLMYLLGVGVALWWFWSEYGGWIVVD 116
Cdd:pfam00499  24 AGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLLLLALLLLVLLSASLTPAAAA 101
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-171 5.74e-61

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 186.50  E-value: 5.74e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012   1 MMYFFDLLLLSLVVGLVGVASNPAPYFAALGLAVAAGVGCGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012  81 TWGAGSVKVYVLMYLLGVGVALWWFWSEYGG--WIVVDEFKEFFMVRGDTGGVSLMYSVGGGMLITCAWVLLLCLFVVLE 158
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEgsWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2206977012 159 LTRGLSRGALRAV 171
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 20-171 4.62e-35

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 120.34  E-value: 4.62e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012  20 ASNPAPYFAALGLAVAAGVGCGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAALAAEPFPETWGAGSVKVYVLMYLLGVG 99
Cdd:MTH00065   20 ASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEAWGSWSVLVYVLFYLLLLI 99

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2206977012 100 VaLWWFWSEYGG--WIVVDEFKEFFMVRGDTGGVSLMYSVGGGMLITCAWVLLLCLFVVLELTRGLSRGALRAV 171
Cdd:MTH00065  100 V-GYILFGCNFSleFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEVTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-171 2.21e-31

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 110.99  E-value: 2.21e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012   1 MMYFFDLLLLSLVVGLVGVASNPAPYFAALGLAVAAGVGCGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012  81 TWGAGSVKVYV---LMYLLGVGVALWWFWSEYGGWIVVDEFKEFFMVRGDTGGVSLMYSVGGGMLITCAWVLLLCLFVVL 157
Cdd:MTH00115   81 AWGDWGVVGYVvgfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2206977012 158 ELTRGLSRGALRAV 171
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-171 1.11e-19

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 80.80  E-value: 1.11e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012   1 MMYFFDLLLLSLVVGLVGVASNPAPYFAALGLAVAAGVGCGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012  81 TWGAGSVKVYVLMYLLGVGVALWWFWS--EYGGWIVVDEFKEFFMvrgdtGGVSLMYSVGGGMLITCAWVLLLCLFVVLE 158
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGgwEMLSWMGVDEANNLDL-----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 2206977012 159 LTRGLSRGALRAV 171
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 40-147 3.00e-18

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 77.15  E-value: 3.00e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012  40 CGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAALAAEPFPETWGAGSV-----------KVYVLMYLLGVGVALWWFWSE 108
Cdd:MTH00109   41 CGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSNKVvlgalllgllmELLLVLYVLKDDEVEVVFNFN 120

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2206977012 109 YGGWIVVDEFKEFFMVRGDTGGVSLMYSVGGGMLITCAW 147
Cdd:MTH00109  121 GLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGW 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 25-170 3.69e-08

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 49.90  E-value: 3.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2206977012  25 PYFAALGLAVAAGVGCGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAALAAEPFPETWGAGSVKVYVLMYLLGVGVAL-W 103
Cdd:MTH00045   23 PYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGEVLVLSLLLSLWVFISFdN 102

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2206977012 104 WFWSEYGGWIVVDEFKEffmvrgdtGGVSLMYSVGGGMLITCAWVLLLCLFVVLELTRGLSRGALRA 170
Cdd:MTH00045  103 FLELSNNNWSLVSLSDL--------VGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
40-116 7.60e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 37.87  E-value: 7.60e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2206977012  40 CGVLVGHGGSLIGLMLFLIYLGGMLVVFAYSAAL-AAEPFPETWGAGSVKVYVLMYLLGVGVALWWFWSEYGGWIVVD 116
Cdd:pfam00499  24 AGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLLLLALLLLVLLSASLTPAAAA 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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