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Conserved domains on  [gi|2312623841|ref|YP_010500213|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Xiphophorus milleri]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.51e-47

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 152.22  E-value: 1.51e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841   1 MSYLMHILLFGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGSGGCFLSLILFLIYLGGMLVVFAYSAAMAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841  81 GWGSWPTLRLMVGYVVGVGFAWGLMGKFWYEEDWLGFDGVVELSVLRGDVGGVSLMYSSGGWLLIGGGWVLLLTLFVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2312623841 161 LTRGLSRGALRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.51e-47

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 152.22  E-value: 1.51e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841   1 MSYLMHILLFGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGSGGCFLSLILFLIYLGGMLVVFAYSAAMAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841  81 GWGSWPTLRLMVGYVVGVGFAWGLMGKFWYEEDWLGFDGVVELSVLRGDVGGVSLMYSSGGWLLIGGGWVLLLTLFVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2312623841 161 LTRGLSRGALRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
50-110 1.29e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 37.10  E-value: 1.29e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2312623841  50 FLSLILFLIYLGGMLVVFAYSAAM-AAEPFPEGWGSWptlRLMVGYVVGVGFAWGLMGKFWY 110
Cdd:pfam00499  34 FLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSG---LPLAALLLGLLLLALLLLVLLS 92
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.51e-47

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 152.22  E-value: 1.51e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841   1 MSYLMHILLFGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGSGGCFLSLILFLIYLGGMLVVFAYSAAMAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841  81 GWGSWPTLRLMVGYVVGVGFAWGLMGKFWYEEDWLGFDGVVELSVLRGDVGGVSLMYSSGGWLLIGGGWVLLLTLFVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2312623841 161 LTRGLSRGALRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 7.06e-32

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 112.25  E-value: 7.06e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841   1 MSYLMHILLFGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGSGGCFLSLILFLIYLGGMLVVFAYSAAMAAEPFPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841  81 GWGSWPTLRLMVGYVVGVGFAWGLMGKFWYEEDWLGFDGvVELSVLRGDVGGVSLMYSSGGWLLIGGGWVLLLTLFVVLE 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYD-TEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                         170
                  ....*....|...
gi 2312623841 161 LTRGLSRGALRAV 173
Cdd:MTH00065  160 VTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 7.20e-23

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 89.04  E-value: 7.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841   1 MSYLMHILLFGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGSGGCFLSLILFLIYLGGMLVVFAYSAAMAAEPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841  81 GWGSWPTLRLMVGYVVGVGFAWGLMGKFW-YEEDWLGFDGVVELSVLRGDVGGVSLMYSSGGWLLIGGGWVLLLTLFVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWgMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2312623841 160 ELTRGLSRGALRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 7.12e-18

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 76.18  E-value: 7.12e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841   1 MSYLMHILLFGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGSGGCFLSLILFLIYLGGMLVVFAYSAAMAAEPFPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841  81 GWGSWPTLRLMVGYVVGVGFAWGLMGKFWYEEDWLGFDGVVELSvlrgdVGGVSLMYSSGGWLLIGGGWVLLLTLFVVLE 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLD-----LSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 2312623841 161 LTRGLSRGALRAV 173
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 50-138 2.48e-14

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 66.75  E-value: 2.48e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2312623841  50 FLSLILFLIYLGGMLVVFAYSAAMAAEPFPEGWGS-WPTL-RLMVGYVVGVGFAWGLMG--------KFWYEEDWLGFDG 119
Cdd:MTH00109   51 FLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSnKVVLgALLLGLLMELLLVLYVLKddevevvfNFNGLGDWVIYDT 130

                          90
                  ....*....|....*....
gi 2312623841 120 vVELSVLRGDVGGVSLMYS 138
Cdd:MTH00109  131 -GGSGFFSEDAMGVAALYS 148
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 50-79 4.18e-06

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 44.51  E-value: 4.18e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 2312623841  50 FLSLILFLIYLGGMLVVFAYSAAMAAEPFP 79
Cdd:MTH00045   48 FLALLLLLIYMGGMLVVFVYSSALSAERYP 77
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
50-110 1.29e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 37.10  E-value: 1.29e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2312623841  50 FLSLILFLIYLGGMLVVFAYSAAM-AAEPFPEGWGSWptlRLMVGYVVGVGFAWGLMGKFWY 110
Cdd:pfam00499  34 FLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSG---LPLAALLLGLLLLALLLLVLLS 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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