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Conserved domains on  [gi|2431513785|ref|YP_010614687|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Kali macrura]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.76e-68

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 204.99  E-value: 2.76e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   1 MTYIVFVFLFGLVLSVIVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPA 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785  81 IWGSPGAAFLMMAYAVGVVLTGCYLGGGWYEASWVPADGLEEYFLFRGDVGGVALMYSSGGNMLVISAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2431513785 161 LTRGLARGTLRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.76e-68

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 204.99  E-value: 2.76e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   1 MTYIVFVFLFGLVLSVIVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPA 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785  81 IWGSPGAAFLMMAYAVGVVLTGCYLGGGWYEASWVPADGLEEYFLFRGDVGGVALMYSSGGNMLVISAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2431513785 161 LTRGLARGTLRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-122 1.13e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 50.96  E-value: 1.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785  17 IVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPAIWGSPGAAFLMMAYAV 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100
                  ....*....|....*....|....*.
gi 2431513785  97 GVVLTGCYLGGGWYEASWVPADGLEE 122
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDV 106
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.76e-68

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 204.99  E-value: 2.76e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   1 MTYIVFVFLFGLVLSVIVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPA 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785  81 IWGSPGAAFLMMAYAVGVVLTGCYLGGGWYEASWVPADGLEEYFLFRGDVGGVALMYSSGGNMLVISAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 2431513785 161 LTRGLARGTLRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 1.12e-42

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 139.98  E-value: 1.12e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   1 MTYIVFVFLFGLVLSVIVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPA 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785  81 IWGSPGAAFLMMAYAVGVVLtGCYLGGGWYEASWVPADGLEEYFLFRGDVGGVALMYSSGGNMLVISAWVLLLTLLVVLE 160
Cdd:MTH00065   81 AWGSWSVLVYVLFYLLLLIV-GYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                         170
                  ....*....|...
gi 2431513785 161 LTRGLARGTLRAV 173
Cdd:MTH00065  160 VTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 3.12e-33

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 116.00  E-value: 3.12e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   1 MTYIVFVFLFGLVLSVIVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPA 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785  81 IWGSPGAAFLMMAYAVGVVLTGCYLGGGW-YEASWVPADGLEEYFLFRGDVGGVALMYSSGGNMLVISAWVLLLTLLVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWgMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 2431513785 160 ELTRGLARGTLRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-149 1.11e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 101.80  E-value: 1.11e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   1 MTYIVFVFLFGLVLSVIVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPA 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2431513785  81 IWGSPGAAF--LMMAYAVGVVLTGCYLGGGWYE--------ASWVPADGlEEYFLFRGDVGGVALMYSSGGNMLVISAW 149
Cdd:MTH00109   82 TWVSNKVVLgaLLLGLLMELLLVLYVLKDDEVEvvfnfnglGDWVIYDT-GGSGFFSEDAMGVAALYSYGTWLVVVTGW 159
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 1.55e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 93.51  E-value: 1.55e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   1 MTYIVFVFLFGLVLSVIVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPA 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785  81 IWGSPGAAFLMMAYAVGVVLTGCYLGGGWYEASWVPADGLEEYflfrgDVGGVALMYSSGGNMLVISAWVLLLTLLVVLE 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNL-----DLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 2431513785 161 LTRGLARGTLRAV 173
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-81 3.45e-12

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 61.07  E-value: 3.45e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   1 MTYIVFVFLfgLVLSVIVVASGpSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPA 80
Cdd:MTH00045    2 VFYLFLILM--LFGSTLVFYSL-SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78


                  .
gi 2431513785  81 I 81
Cdd:MTH00045   79 V 79
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-122 1.13e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 50.96  E-value: 1.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785  17 IVVASGPSPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALVADPDPAIWGSPGAAFLMMAYAV 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100
                  ....*....|....*....|....*.
gi 2431513785  97 GVVLTGCYLGGGWYEASWVPADGLEE 122
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDV 106
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 3-74 2.85e-05

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 42.18  E-value: 2.85e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2431513785   3 YIVFVFLFGLVLSVIVVASgpsPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVALV 74
Cdd:MTH00152    4 MILLSVCFSLFLLLPLSKQ---PLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 4-73 4.16e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 38.83  E-value: 4.16e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2431513785   4 IVFVFLFGLVLSVIVVASgpsPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVAL 73
Cdd:MTH00212    5 LLLSLLLLLMLLFPLSAH---PLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVAL 71
ND6 MTH00015
NADH dehydrogenase subunit 6; Validated
 24-73 9.34e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 164590  Cd Length: 155  Bit Score: 34.83  E-value: 9.34e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2431513785  24 SPIFAALALVVVAGMGCGVLVKYGGSFLSLVLFLIYLGGMLVVFAYSVAL 73
Cdd:MTH00015   22 TPITLGINILMMALLLATTMASALSSWFAFLTFLIYVGGMLVMFAYFLAL 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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