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Conserved domains on  [gi|56694730|ref|YP_164450|]
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helicase-primase subunit [Cercopithecine alphaherpesvirus 2]

Protein Classification

PHA03144 family protein( domain architecture ID 10010436)

PHA03144 family protein

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PHA03144 PHA03144
helicase-primase primase subunit; Provisional
1-740 0e+00

helicase-primase primase subunit; Provisional


:

Pssm-ID: 223000  Cd Length: 746  Bit Score: 771.22  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730    1 MGEDGLAWAEESVCAVTLYAAWLPPRTRDRLHALLYLLCRDARGDAVARFAEVAVASSELQ-AFYGPGEISAAGAVAAAR 79
Cdd:PHA03144   1 MMEDGVAWAEGSVCATSLYSLWTPPRTPDRLHALVYLLCRDAAGDYTARFAEVSVSSNELQtGFRGPADVTAARAVAAAR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   80 AAASPAAAPLETLNDPALWRALYASALAALEREVGGAPLFVPARVGRDPRTGLVARIEAAPGGRP-VAPRGAALGVDAQV 158
Cdd:PHA03144  81 AAAAPAAWPLEPLGDPALWKALYASVLAALRRQVGRFAFYSPLRFGVDPQTGLVVRIEPAPGGGEpAAPRAAILNVTAKV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  159 ATDPLALAAHVAARPAARLAWARLAAIQD---TPQCASAASLAVRIDTGTARFAREYTTLTFPPVRKEGAVGDVFEVREA 235
Cdd:PHA03144 161 DLDPLALAAHAASSPGASLARARLAAIRDgyfTPSCASDASLEVEITTKTARFAREYDTLQFPPVKREGAMADLFEVRER 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  236 VLRPRGHaQAVTARVLVPRGYEYFAVRAEGFSAPALVALFRQWHLTVHAAPGALPPIFAFLGPEFEPRGGAVDHFAVLGF 315
Cdd:PHA03144 241 TLRPRGH-QRVTARVLVPRGFDCFVACAEGFSAPALMALYRQWHATVFAAPGALVPIFAFLGPELEPRGEEVDYFCVLGF 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  316 PGWPTLKVPAGAAAVPAAALTAHAELAGAWPAAGARALAPARLWAAAAAGAPGRLSPALR-------------RPATPGL 382
Cdd:PHA03144 320 PGWPTLKVSAAAAEAVREALAAYVLLDGLWPALGARAFHPLAPWAPEDRAAAGSLTPRLReaaarlqnglrdkWPAGRVS 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  383 RLLDPPAVIGPVCLARFRFPGLEARLAAALCGlgleprADPRDPLARGARcwralAADARPWARAVAALALAEAREECPA 462
Cdd:PHA03144 400 CILDHPAVIGGVWLAKFDFSAFFPTLYLALFP------GHERLARAVRAR-----ARREKPWLKAALVSFFGGLQHICPA 468
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  463 FARVLDGVVAAVGLRLEAAAGDVDLAVCGNEGASLWGVLNVDPQ---GAAGPAAVERARAALEGVAGEALAGGGLLRPEE 539
Cdd:PHA03144 469 AYRALIALANAVSRALERAANAVGFAVCTYVKDGFWGVLGVDPQdavSADALAAAERARAACQAAAEAVLADMGLLLPEG 548
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  540 PPPSLELEGIYTHAVLWSQTGAWFWNARTDADRLEGFPQRgpaYAAAAAATRRALRGAVAAYAEGAGAEKARLAAEEALD 619
Cdd:PHA03144 549 APLHLRLEGLYTHAVSWSQHGYWLWNRRTDTEDFVGFPLR---SAAARAAKAALRALLRAAVADSADAETLRQAAREACD 625
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  620 GLVLEAFARRLDAEYWAVAEGPSDPGDTPPAAALRGGALLDSERHSRRVVRVCGGpDGGSVAVPIDLYPRPLVLPPIDCA 699
Cdd:PHA03144 626 RLVLEAFARRLDAEFWSVPTPISDPSDPLPAAAFRGGALLDADHGSRRVVRVCGG-DCEPVPVPWDLYPRPLVLPPIDCA 704
                        730       740       750       760
                 ....*....|....*....|....*....|....*....|...
gi 56694730  700 HHLRDVLAEAEAVLRGALAGLWGEDGG--FAYPFEErFLFLFD 740
Cdd:PHA03144 705 HHLRPILAEAESMLNGALSALWGEDEPfeVTYPFED-FAFLFA 746
 
Name Accession Description Interval E-value
PHA03144 PHA03144
helicase-primase primase subunit; Provisional
1-740 0e+00

helicase-primase primase subunit; Provisional


Pssm-ID: 223000  Cd Length: 746  Bit Score: 771.22  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730    1 MGEDGLAWAEESVCAVTLYAAWLPPRTRDRLHALLYLLCRDARGDAVARFAEVAVASSELQ-AFYGPGEISAAGAVAAAR 79
Cdd:PHA03144   1 MMEDGVAWAEGSVCATSLYSLWTPPRTPDRLHALVYLLCRDAAGDYTARFAEVSVSSNELQtGFRGPADVTAARAVAAAR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   80 AAASPAAAPLETLNDPALWRALYASALAALEREVGGAPLFVPARVGRDPRTGLVARIEAAPGGRP-VAPRGAALGVDAQV 158
Cdd:PHA03144  81 AAAAPAAWPLEPLGDPALWKALYASVLAALRRQVGRFAFYSPLRFGVDPQTGLVVRIEPAPGGGEpAAPRAAILNVTAKV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  159 ATDPLALAAHVAARPAARLAWARLAAIQD---TPQCASAASLAVRIDTGTARFAREYTTLTFPPVRKEGAVGDVFEVREA 235
Cdd:PHA03144 161 DLDPLALAAHAASSPGASLARARLAAIRDgyfTPSCASDASLEVEITTKTARFAREYDTLQFPPVKREGAMADLFEVRER 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  236 VLRPRGHaQAVTARVLVPRGYEYFAVRAEGFSAPALVALFRQWHLTVHAAPGALPPIFAFLGPEFEPRGGAVDHFAVLGF 315
Cdd:PHA03144 241 TLRPRGH-QRVTARVLVPRGFDCFVACAEGFSAPALMALYRQWHATVFAAPGALVPIFAFLGPELEPRGEEVDYFCVLGF 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  316 PGWPTLKVPAGAAAVPAAALTAHAELAGAWPAAGARALAPARLWAAAAAGAPGRLSPALR-------------RPATPGL 382
Cdd:PHA03144 320 PGWPTLKVSAAAAEAVREALAAYVLLDGLWPALGARAFHPLAPWAPEDRAAAGSLTPRLReaaarlqnglrdkWPAGRVS 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  383 RLLDPPAVIGPVCLARFRFPGLEARLAAALCGlgleprADPRDPLARGARcwralAADARPWARAVAALALAEAREECPA 462
Cdd:PHA03144 400 CILDHPAVIGGVWLAKFDFSAFFPTLYLALFP------GHERLARAVRAR-----ARREKPWLKAALVSFFGGLQHICPA 468
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  463 FARVLDGVVAAVGLRLEAAAGDVDLAVCGNEGASLWGVLNVDPQ---GAAGPAAVERARAALEGVAGEALAGGGLLRPEE 539
Cdd:PHA03144 469 AYRALIALANAVSRALERAANAVGFAVCTYVKDGFWGVLGVDPQdavSADALAAAERARAACQAAAEAVLADMGLLLPEG 548
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  540 PPPSLELEGIYTHAVLWSQTGAWFWNARTDADRLEGFPQRgpaYAAAAAATRRALRGAVAAYAEGAGAEKARLAAEEALD 619
Cdd:PHA03144 549 APLHLRLEGLYTHAVSWSQHGYWLWNRRTDTEDFVGFPLR---SAAARAAKAALRALLRAAVADSADAETLRQAAREACD 625
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  620 GLVLEAFARRLDAEYWAVAEGPSDPGDTPPAAALRGGALLDSERHSRRVVRVCGGpDGGSVAVPIDLYPRPLVLPPIDCA 699
Cdd:PHA03144 626 RLVLEAFARRLDAEFWSVPTPISDPSDPLPAAAFRGGALLDADHGSRRVVRVCGG-DCEPVPVPWDLYPRPLVLPPIDCA 704
                        730       740       750       760
                 ....*....|....*....|....*....|....*....|...
gi 56694730  700 HHLRDVLAEAEAVLRGALAGLWGEDGG--FAYPFEErFLFLFD 740
Cdd:PHA03144 705 HHLRPILAEAESMLNGALSALWGEDEPfeVTYPFED-FAFLFA 746
Herpes_HEPA pfam03324
Herpesvirus DNA helicase/primase complex associated protein; This family includes HSV UL8, ...
228-321 1.62e-27

Herpesvirus DNA helicase/primase complex associated protein; This family includes HSV UL8, EHV-1 54, VZV 52 AND HCMV 102.


Pssm-ID: 367447 [Multi-domain]  Cd Length: 95  Bit Score: 106.71  E-value: 1.62e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   228 DVFEVREAVLRPRGHAqaVTARVLVPRGYEYFAVRAEGFSAPALVALFRQWHLTVHAAPGALPPIFAFLGPEFEPRGGAV 307
Cdd:pfam03324   4 DIFEVVDCALVLGGRQ--VTVRVLLPPAFDCLVTNDECFWNLALVAFFRALHEKIFGEPGGLVPLFAYLGPGLNPEGEDF 81
                          90
                  ....*....|....
gi 56694730   308 DHFAVLGFPGWPTL 321
Cdd:pfam03324  82 DYFCSPGFPGFPNL 95
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
200-724 4.33e-08

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 56.80  E-value: 4.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  200 RIDTGTARFAREY--TTLTFPPVRKEGAVGDVFEVREAVLRPRGHAQAVTARVLVPRGYEYFAVRAEGFSAPALVALFRQ 277
Cdd:COG3321  860 RVPLPTYPFQREDaaAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAA 939
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  278 WHLTVHAAPGALPPIFAFLGPEFEPRGGAVDHFAVLGFPGWPTLKVPAGAAAVPAAALTAHAELAGAWPAAGARALAPAR 357
Cdd:COG3321  940 AALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAA 1019
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  358 LWAAAAAGAPGRLSPALRRPATPGLRLLDPPAVIGPVCLARFRFPGLEARLAAALCGLGLEPRADPRDPLARGARCWRAL 437
Cdd:COG3321 1020 ALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALAL 1099
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  438 AADARPWARAVAALALAEAREECPAFARVLDGVVAAVGLRLEAAAGDVDLAVCGNEGASLWGVLNVDPQGAAGPAAVERA 517
Cdd:COG3321 1100 AALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALAL 1179
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  518 RAALEGVAGEALAGGGLLRPEEPPPSLELEGIYTHAVLWSQTGAWFWNARTDADRLEGFPQRGPAYAAAAAATRRALRGA 597
Cdd:COG3321 1180 ALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAAL 1259
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  598 VAAYAEGAGAEKARLAAEEALDGLVLEAFARRLDAEYWAVAEGPSDPGDTPPAAALRGGALLDSERHSRRVVRVCGGPDG 677
Cdd:COG3321 1260 AALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAALAAAVAA 1339
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*..
gi 56694730  678 GSVAVPIDLYPRPLVLPPIDCAHHLRDVLAEAEAVLRGALAGLWGED 724
Cdd:COG3321 1340 ALALAAAAAAAAAAAAAAAAAAALAAAAGAAAAAAALALAALAAAVA 1386
 
Name Accession Description Interval E-value
PHA03144 PHA03144
helicase-primase primase subunit; Provisional
1-740 0e+00

helicase-primase primase subunit; Provisional


Pssm-ID: 223000  Cd Length: 746  Bit Score: 771.22  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730    1 MGEDGLAWAEESVCAVTLYAAWLPPRTRDRLHALLYLLCRDARGDAVARFAEVAVASSELQ-AFYGPGEISAAGAVAAAR 79
Cdd:PHA03144   1 MMEDGVAWAEGSVCATSLYSLWTPPRTPDRLHALVYLLCRDAAGDYTARFAEVSVSSNELQtGFRGPADVTAARAVAAAR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   80 AAASPAAAPLETLNDPALWRALYASALAALEREVGGAPLFVPARVGRDPRTGLVARIEAAPGGRP-VAPRGAALGVDAQV 158
Cdd:PHA03144  81 AAAAPAAWPLEPLGDPALWKALYASVLAALRRQVGRFAFYSPLRFGVDPQTGLVVRIEPAPGGGEpAAPRAAILNVTAKV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  159 ATDPLALAAHVAARPAARLAWARLAAIQD---TPQCASAASLAVRIDTGTARFAREYTTLTFPPVRKEGAVGDVFEVREA 235
Cdd:PHA03144 161 DLDPLALAAHAASSPGASLARARLAAIRDgyfTPSCASDASLEVEITTKTARFAREYDTLQFPPVKREGAMADLFEVRER 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  236 VLRPRGHaQAVTARVLVPRGYEYFAVRAEGFSAPALVALFRQWHLTVHAAPGALPPIFAFLGPEFEPRGGAVDHFAVLGF 315
Cdd:PHA03144 241 TLRPRGH-QRVTARVLVPRGFDCFVACAEGFSAPALMALYRQWHATVFAAPGALVPIFAFLGPELEPRGEEVDYFCVLGF 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  316 PGWPTLKVPAGAAAVPAAALTAHAELAGAWPAAGARALAPARLWAAAAAGAPGRLSPALR-------------RPATPGL 382
Cdd:PHA03144 320 PGWPTLKVSAAAAEAVREALAAYVLLDGLWPALGARAFHPLAPWAPEDRAAAGSLTPRLReaaarlqnglrdkWPAGRVS 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  383 RLLDPPAVIGPVCLARFRFPGLEARLAAALCGlgleprADPRDPLARGARcwralAADARPWARAVAALALAEAREECPA 462
Cdd:PHA03144 400 CILDHPAVIGGVWLAKFDFSAFFPTLYLALFP------GHERLARAVRAR-----ARREKPWLKAALVSFFGGLQHICPA 468
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  463 FARVLDGVVAAVGLRLEAAAGDVDLAVCGNEGASLWGVLNVDPQ---GAAGPAAVERARAALEGVAGEALAGGGLLRPEE 539
Cdd:PHA03144 469 AYRALIALANAVSRALERAANAVGFAVCTYVKDGFWGVLGVDPQdavSADALAAAERARAACQAAAEAVLADMGLLLPEG 548
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  540 PPPSLELEGIYTHAVLWSQTGAWFWNARTDADRLEGFPQRgpaYAAAAAATRRALRGAVAAYAEGAGAEKARLAAEEALD 619
Cdd:PHA03144 549 APLHLRLEGLYTHAVSWSQHGYWLWNRRTDTEDFVGFPLR---SAAARAAKAALRALLRAAVADSADAETLRQAAREACD 625
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  620 GLVLEAFARRLDAEYWAVAEGPSDPGDTPPAAALRGGALLDSERHSRRVVRVCGGpDGGSVAVPIDLYPRPLVLPPIDCA 699
Cdd:PHA03144 626 RLVLEAFARRLDAEFWSVPTPISDPSDPLPAAAFRGGALLDADHGSRRVVRVCGG-DCEPVPVPWDLYPRPLVLPPIDCA 704
                        730       740       750       760
                 ....*....|....*....|....*....|....*....|...
gi 56694730  700 HHLRDVLAEAEAVLRGALAGLWGEDGG--FAYPFEErFLFLFD 740
Cdd:PHA03144 705 HHLRPILAEAESMLNGALSALWGEDEPfeVTYPFED-FAFLFA 746
PHA03140 PHA03140
helicase-primase primase subunit; Provisional
13-739 2.15e-77

helicase-primase primase subunit; Provisional


Pssm-ID: 222998  Cd Length: 772  Bit Score: 264.88  E-value: 2.15e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   13 VCAVTLYAAWLPP--RTRDRLHALLYLLCRDARGDAVARFAEVAVASSELQAFY-GPGEISAAGAVAA--ARAAASPAAA 87
Cdd:PHA03140  15 ICAASIYSAWTQGgdRAREYPYVLLYLLCKRGDGGYDPVFAEITVLAEDLCRYSrHAGDVTAATLASLcrAASSAAPDAW 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   88 PLETLNDPALWRALYASALAALEREVGGAPLFVPARVGRDPRTGL-VARIEAAPGGRPVAPRGAALGVDAQVATDPLALA 166
Cdd:PHA03140  95 PLEPLGNADTWRCLYGSALATLRRRLGFFSFYSPVRFGTDTATGLlVKAEPAPDATADAAPSTGVLRAALRVAIEESAVR 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  167 AHVAARPAARLAWARLAAIQDTPQCASAASLAVRIDTGTARFAREYTTLTFPPVRKEGAVGDVFEVREAVLRPRGHAqAV 246
Cdd:PHA03140 175 ACAAAAPGGSLAYARLCALKDGHANAPGTALEFELTTKTARIYRSYASIFSPPRERAGRLSDVFNLREYRVCTSGGR-AT 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  247 TARVLVPRGYEYFAVRAEGFSAPALVALFRQWHLTVHAAPGALPPIFAFLGPEFEPRGGAVDHFAVLGFPGWPTLKVPAG 326
Cdd:PHA03140 254 VVRVLLPVGFDCLVTDARVTSPLSALLVYRQWYAAAFGKPGGPRQILAYLGPELSPGGEERDYFCTVGFPGWTTLRTSTP 333
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  327 AAAVPAAALTAHAELAGAWPAAGARALAPARLWAAAAAGAPGRLSP---ALRR--------------PATPGLRLLDPPA 389
Cdd:PHA03140 334 DAESVRDALEAYVETDGLWPVTGIHAFHYLAPWDFHPPLPVAGLDRriaAARRalpagggsgdgadwPAGRISTILDSPV 413
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  390 VIGPVCLARFRFPGLEARLAAALCglglepradprdPL-ARGARCWRALAADARPWARAVAALALAEAREECPAFARVLD 468
Cdd:PHA03140 414 CVRDLWLAKFDFSAFFPTIYCALF------------PEhARLARIIRARRRRGRPCLKPALVTFFGGLRHIHPPAYKAII 481
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  469 GVVAAVGLRLEAAAGDVDLAVCGNEGASLWGVL-NVDPQGAAGPAAVERA---RAALEGVAGEALAGGGLLRP-EEPPPS 543
Cdd:PHA03140 482 ALANAISACVERAANERNFAICTYVKDGFWGAFgDLVPGAVSRDAARAAAlalRDDCERAVEAVLRDDLGLRPaEGAEPH 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  544 LELEGIYTHAVLWSQTGAWFWNARTDA-DRLEGFPQR-----------GPAYAAAAAATRRALRGAVAAYAEGAGAEKAR 611
Cdd:PHA03140 562 LRFEGVFTHAVSWCTTGYWLWNATTGEsEHLVGVPCRseaardakeslAGLLCRAVAIRERLYASTWTVSNYITWPGDTV 641
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  612 LAAEEALDGLVLEAFARRLDAEYWAVAEGPSDPGdTPPAAALRGGALLDSERHSRRVVRVCG-GPDGGSVAVPIDLYPRP 690
Cdd:PHA03140 642 AAAAAACDALVHAAFERRGDVRYWSATAPIGDWG-AVPRSALSGGDMLDKDHKPRQYVLVRGhIPEAAPFPLPWTLYRAP 720
                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|...
gi 56694730  691 LVLPPIDCAHHLRDVLAEAEAVLRGALAGlwGEDGGFAYP-FE---ERFLFLF 739
Cdd:PHA03140 721 VCLPPIDCRAHLAPLLQTFARMINGALAA--GNDFGEPPTkFEydlADYDFLF 771
PHA03181 PHA03181
helicase-primase primase subunit; Provisional
13-738 6.99e-43

helicase-primase primase subunit; Provisional


Pssm-ID: 165452  Cd Length: 764  Bit Score: 166.63  E-value: 6.99e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   13 VCAVTLYAAWLPPRTRDRLHALLYLLCRDARGDAVARFAEVAVASSELQAFYG--PGEISAAGAVAAARAAASPAAAPLE 90
Cdd:PHA03181  19 ICYTTLYRLWTSSNRTEGLTALCYLLFRNVCGNYSAHYSTVNFSGKSLAKAWGlnPDTITDATLASMANAASVTGRWPSC 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   91 TLNDPALWRALYASALAALEREVGGAPLFVPARVGRDPRTGLVARIEAAPGGRpVAPRGAALGVDAQVATDPLALAAHVA 170
Cdd:PHA03181  99 NADQHTLWKALLAFTLAKLRHRLGYHAYYTPVNMYVDKITGLVLSCEPLNGER-YKPRPGLLKTDGTINVEESSLLSTAM 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  171 ARPAARLAWARLAAIQDTPQCASAASLAVRIDTGTARFAREYTTLTFPPVR-KEGAVGDVFEVREAVLRPRGHAQAVTAR 249
Cdd:PHA03181 178 KFTEGATLAHIKLSALKNIETIPEFDARIEIQTKEDRFYREYKSVSSRTKKtKLHNSNNIFHVVEKPLILDGSQAPVRTL 257
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  250 VLVPRGYEYFAVRAEGFSAPALVALFRQWHLTVHAAPGA----LPPIFAFLGPEFEPRGGAVDHFAVLGFPGWPTLKVPA 325
Cdd:PHA03181 258 TLVPTSFDCLVTTPAEFSLSALLAIYAKWHEKLYSTAGGsekiLTPIFTYIGPETNPRGEDVDYACIIGFPGWPMVKSST 337
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  326 GAAAVPAAALTAHAELAGAWPAAGA---------RALAPARLWAAAAAGAPGRLSPALRRPA---TPGlRL---LDPPAV 390
Cdd:PHA03181 338 ASHLAIKEAIDSYAATDGLWPLAGPrtfhllapwRPENHPSPTIDICHYLKAESNVARGRIAddwTEG-RItciFREPTL 416
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  391 IGPVCLARFRFPGLEARLAaalcgLGLEP-RADPRDplARGARCWRalaadARPWARAVAALALAEAREECPAFARVLDG 469
Cdd:PHA03181 417 IENAAIAKFDFSAFFATLY-----LGLFPcHSRLRD--AVKARLRR-----EKDWLKRPIVEFGGLLKHFREDVYKAIIG 484
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  470 VVAAVGLRLEAAAGDVDLAVCGNEGASLWGVLNVDPQGAAGPA-----AVERARAALEGVAGEALAGGGLLRPEEPPPSL 544
Cdd:PHA03181 485 IGNHISLEVEATASTLMFAPCTYVKDGMWGTFIDKANNVIVSPegnenIFETLRVACNESANRLATSIGLRFPDGINLQM 564
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  545 ELEGIYTHAVLWSQTGAWFWNARTDADRLEGFPQRGPAYAAAAAATRRALRGAVAAYAEGAGAEKARLAAEEALDGLVLE 624
Cdd:PHA03181 565 RLEGVYTHAMSWNANCYWLWNRNTRESDFVGFPKQPEFATHAKEALSTLLEEICLCNDTDESLLTIQEKVQKVFEELLYM 644
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  625 AFARRLDAEYWAVAEGPSDpgDTPPAAAL--RGGALLDSERHSRRVVRVCGGpDGGSVAVPIDLYP-RPLVLPPIDCAHH 701
Cdd:PHA03181 645 AFKKRGDASFWSCPTESYD--DTLYIVALgsKAAARFDTSAFRREMVQTVTT-DGNIVPVTCSLFEgTHFILPAISCIDH 721
                        730       740       750       760
                 ....*....|....*....|....*....|....*....|
gi 56694730  702 LRDVLAEAEAVLRGALAGLWG--EDGGFAYPFEE-RFLFL 738
Cdd:PHA03181 722 MKPILSAFSRLLISVLASKWPnvDQGSFTFDVEHyRFMFI 761
Herpes_HEPA pfam03324
Herpesvirus DNA helicase/primase complex associated protein; This family includes HSV UL8, ...
228-321 1.62e-27

Herpesvirus DNA helicase/primase complex associated protein; This family includes HSV UL8, EHV-1 54, VZV 52 AND HCMV 102.


Pssm-ID: 367447 [Multi-domain]  Cd Length: 95  Bit Score: 106.71  E-value: 1.62e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730   228 DVFEVREAVLRPRGHAqaVTARVLVPRGYEYFAVRAEGFSAPALVALFRQWHLTVHAAPGALPPIFAFLGPEFEPRGGAV 307
Cdd:pfam03324   4 DIFEVVDCALVLGGRQ--VTVRVLLPPAFDCLVTNDECFWNLALVAFFRALHEKIFGEPGGLVPLFAYLGPGLNPEGEDF 81
                          90
                  ....*....|....
gi 56694730   308 DHFAVLGFPGWPTL 321
Cdd:pfam03324  82 DYFCSPGFPGFPNL 95
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
200-724 4.33e-08

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 56.80  E-value: 4.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  200 RIDTGTARFAREY--TTLTFPPVRKEGAVGDVFEVREAVLRPRGHAQAVTARVLVPRGYEYFAVRAEGFSAPALVALFRQ 277
Cdd:COG3321  860 RVPLPTYPFQREDaaAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAA 939
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  278 WHLTVHAAPGALPPIFAFLGPEFEPRGGAVDHFAVLGFPGWPTLKVPAGAAAVPAAALTAHAELAGAWPAAGARALAPAR 357
Cdd:COG3321  940 AALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAA 1019
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  358 LWAAAAAGAPGRLSPALRRPATPGLRLLDPPAVIGPVCLARFRFPGLEARLAAALCGLGLEPRADPRDPLARGARCWRAL 437
Cdd:COG3321 1020 ALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALAL 1099
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  438 AADARPWARAVAALALAEAREECPAFARVLDGVVAAVGLRLEAAAGDVDLAVCGNEGASLWGVLNVDPQGAAGPAAVERA 517
Cdd:COG3321 1100 AALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALAL 1179
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  518 RAALEGVAGEALAGGGLLRPEEPPPSLELEGIYTHAVLWSQTGAWFWNARTDADRLEGFPQRGPAYAAAAAATRRALRGA 597
Cdd:COG3321 1180 ALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAAL 1259
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56694730  598 VAAYAEGAGAEKARLAAEEALDGLVLEAFARRLDAEYWAVAEGPSDPGDTPPAAALRGGALLDSERHSRRVVRVCGGPDG 677
Cdd:COG3321 1260 AALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAALAAAVAA 1339
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*..
gi 56694730  678 GSVAVPIDLYPRPLVLPPIDCAHHLRDVLAEAEAVLRGALAGLWGED 724
Cdd:COG3321 1340 ALALAAAAAAAAAAAAAAAAAAALAAAAGAAAAAAALALAALAAAVA 1386
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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