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Conserved domains on  [gi|62161315|ref|YP_214932|]
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NADH dehydrogenase subunit 3 (mitochondrion) [Homalodisca vitripennis]

Protein Classification

NADH dehydrogenase subunit 3( domain architecture ID 10009596)

NADH dehydrogenase subunit 3 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 3-115 1.04e-21

NADH dehydrogenase subunit 3; Provisional


:

Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 82.52  E-value: 1.04e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    3 LTMIFFFITMILMLIIMMLIIMIGKKSIIEYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTMY 82
Cdd:MTH00161   1 MILIILLIILLISIILMILASLLSKKSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFK 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 62161315   83 NVNMMTWLLTSIMFTLILMIGLYHEWYNGMLNW 115
Cdd:MTH00161  81 TSNMMSWLITSSFFILILLLGLYYEWNQGALEW 113
 
Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 3-115 1.04e-21

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 82.52  E-value: 1.04e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    3 LTMIFFFITMILMLIIMMLIIMIGKKSIIEYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTMY 82
Cdd:MTH00161   1 MILIILLIILLISIILMILASLLSKKSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFK 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 62161315   83 NVNMMTWLLTSIMFTLILMIGLYHEWYNGMLNW 115
Cdd:MTH00161  81 TSNMMSWLITSSFFILILLLGLYYEWNQGALEW 113
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
34-114 2.92e-09

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 50.11  E-value: 2.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPmILTMYNVNMMTWLLTSIMFTLILMIGLYHEWYNGML 113
Cdd:pfam00507  15 EKLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVEVVFLFP-WAVSFRELGWFGFVEMLIFIAILLVGLVYAWKKGAL 93


                  .
gi 62161315   114 N 114
Cdd:pfam00507  94 E 94
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 34-115 8.63e-07

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 43.96  E-value: 8.63e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315  34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIfdieiiiILPMILTMY----NVNMMTW--LLTSIMFTLILMIGLYHE 107
Cdd:COG0838  37 EKLSPYECGIEPVGDARIRFSVRYYLVALLFVI-------FDVEVVFLFpwavVFRELGWfgLIEMLVFIAILLVGLIYA 109


                ....*...
gi 62161315 108 WYNGMLNW 115
Cdd:COG0838 110 WKKGALEW 117
 
Name Accession Description Interval E-value
ND3 MTH00161
NADH dehydrogenase subunit 3; Provisional
 3-115 1.04e-21

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177217 [Multi-domain]  Cd Length: 113  Bit Score: 82.52  E-value: 1.04e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    3 LTMIFFFITMILMLIIMMLIIMIGKKSIIEYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTMY 82
Cdd:MTH00161   1 MILIILLIILLISIILMILASLLSKKSIMDREKSSPFECGFDPKSSARLPFSLRFFLIAIIFLIFDVEIALLLPMIFIFK 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 62161315   83 NVNMMTWLLTSIMFTLILMIGLYHEWYNGMLNW 115
Cdd:MTH00161  81 TSNMMSWLITSSFFILILLLGLYYEWNQGALEW 113
ND3 MTH00148
NADH dehydrogenase subunit 3; Provisional
 1-117 4.63e-21

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214433 [Multi-domain]  Cd Length: 117  Bit Score: 81.06  E-value: 4.63e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    1 MNLTMIFFFITMILMLIIMMLIIMIGKKSIIEYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILT 80
Cdd:MTH00148   1 MLSILLSLLFALILSPVLLLLGLVLSKRSYSDREKSSPFECGFDPISSARSPFSLRFFLLAILFLVFDVEIVLLFPVLQS 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 62161315   81 MYNVNMMTWLLTSIMFTLILMIGLYHEWYNGMLNWAK 117
Cdd:MTH00148  81 LGSSFSVWSLTSLFIFLLILILGLFHEWNEGSLDWVS 117
ND3 MTH00042
NADH dehydrogenase subunit 3; Validated
 1-116 9.44e-20

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 177117 [Multi-domain]  Cd Length: 116  Bit Score: 77.71  E-value: 9.44e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    1 MNLTMIFFFITMILMLIIMMLIIMIGKKSIiEYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILT 80
Cdd:MTH00042   1 MTNLIFFLLIILILTSLLLLAGHFLPSRSP-DLEKSSPYECGFDPLNSARLPFSFRFFLVAILFLLFDLEIALLFPLPPA 79

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 62161315   81 MYNVNMMTWLLTSIMFTLILMIGLYHEWYNGMLNWA 116
Cdd:MTH00042  80 TLITNPSTLLPISLIFLIILTIGLVYEWVNGGLEWA 115
ND3 MTH00012
NADH dehydrogenase subunit 3; Validated
 1-116 2.24e-17

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164588 [Multi-domain]  Cd Length: 117  Bit Score: 71.81  E-value: 2.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    1 MNLTMIFFFITMILMLIIMMLIIMIGKKSIIEYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILT 80
Cdd:MTH00012   1 MSLMMIPMMISLILPPLVLGAAWVLAARSTADREKTSPFECGFDPHKTARIPFSLRFFLLAIIFIVFDIEIVLLMPVPTI 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 62161315   81 MYNVNMMTWLLTSIMFTLILMIGLYHEWYNGMLNWA 116
Cdd:MTH00012  81 LMTSTSKTVVYTSILFLLILVIGLIHEWREGSLDWS 116
ND3 MTH00202
NADH dehydrogenase subunit 3; Provisional
 1-117 9.66e-17

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214455 [Multi-domain]  Cd Length: 117  Bit Score: 70.02  E-value: 9.66e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    1 MNLTMIFFFITMILMLIIMMLIIMIGKKSIIEYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILT 80
Cdd:MTH00202   1 MLLILFMSILSILISSLLFLVSWMLSFRSLMDREKSSPFECGFDPKESARLPFSMRFFLLAVIFLVFDIEIALLLPLPLV 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 62161315   81 MYNVNMMTWLLTSIMFTLILMIGLYHEWYNGMLNWAK 117
Cdd:MTH00202  81 LKSSWSKGGLLGGTIFLLILIGGLIHEWKEGSLDWVK 117
ND3 MTH00106
NADH dehydrogenase subunit 3; Provisional
 34-117 1.27e-11

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177168 [Multi-domain]  Cd Length: 115  Bit Score: 56.87  E-value: 1.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315   34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTMYNVNMMTWLLTSIMFTLILMIGLYHEWYNGML 113
Cdd:MTH00106  32 EKASPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQTNNLNTMLTMALLLISLLALSLAYEWTQKGL 111


                 ....
gi 62161315  114 NWAK 117
Cdd:MTH00106 112 EWTE 115
ND3 MTH00069
NADH dehydrogenase subunit 3; Provisional
 34-116 1.42e-11

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177141 [Multi-domain]  Cd Length: 114  Bit Score: 56.54  E-value: 1.42e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315   34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTMYNVNMMTWLLTSIMFTLILMIGLYHEWYNGML 113
Cdd:MTH00069  31 EKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPTPWASQLNTPTNTLFWSTLILILLTLGLIYEWIQGGL 110


                 ...
gi 62161315  114 NWA 116
Cdd:MTH00069 111 EWA 113
ND3 MTH00203
NADH dehydrogenase subunit 3; Provisional
 1-115 2.09e-11

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 214456 [Multi-domain]  Cd Length: 112  Bit Score: 56.06  E-value: 2.09e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    1 MNLTMIFFFITMILMLIIMMLIIMIGKkSIIEYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILT 80
Cdd:MTH00203   1 MNLIMLFFLIALLLSLILLFIAFWLPK-VNPDGEKLSPYECGFDPLGSARLPFSLQFFLVALSFLLFDLEIALLLPLPWS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 62161315   81 MYNVNMMTWLLTsiMFTLILMIGLYHEWYNGMLNW 115
Cdd:MTH00203  80 NQLSSLSLLLAF--LFLILLTLGLIYEWLQGGLEW 112
ND3 MTH00113
NADH dehydrogenase subunit 3; Provisional
 34-116 2.46e-11

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177175 [Multi-domain]  Cd Length: 114  Bit Score: 56.04  E-value: 2.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315   34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTM-YNVNMMTWLLTSIMFTLiLMIGLYHEWYNGM 112
Cdd:MTH00113  32 EKLSPYECGFDPLGSARLPFSIRFFLVAILFLLFDLEIALLLPLPWAInLTTPTTTLTWATIILTL-LTLGLIYEWLQGG 110


                 ....
gi 62161315  113 LNWA 116
Cdd:MTH00113 111 LEWA 114
ND3 MTH00136
NADH dehydrogenase subunit 3; Provisional
 32-116 3.16e-10

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177194 [Multi-domain]  Cd Length: 116  Bit Score: 53.00  E-value: 3.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315   32 EYQKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMiltMYNVNMMTWLLTSIMFTLILM---IGLYHEW 108
Cdd:MTH00136  31 DHEKLSPYECGFDPLGSARLPFSLRFFLVAILFLLFDLEIALLLPL---PWGDQLPSPLLTFFWATAVLIlltLGLIYEW 107


                 ....*...
gi 62161315  109 YNGMLNWA 116
Cdd:MTH00136 108 LQGGLEWA 115
Oxidored_q4 pfam00507
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;
34-114 2.92e-09

NADH-ubiquinone/plastoquinone oxidoreductase, chain 3;


Pssm-ID: 459838 [Multi-domain]  Cd Length: 94  Bit Score: 50.11  E-value: 2.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315    34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPmILTMYNVNMMTWLLTSIMFTLILMIGLYHEWYNGML 113
Cdd:pfam00507  15 EKLSPYECGFDPVGDARLRFSVRFYLVAILFLIFDVEVVFLFP-WAVSFRELGWFGFVEMLIFIAILLVGLVYAWKKGAL 93


                  .
gi 62161315   114 N 114
Cdd:pfam00507  94 E 94
ND3 MTH00055
NADH dehydrogenase subunit 3; Provisional
 34-115 4.22e-08

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 177128 [Multi-domain]  Cd Length: 118  Bit Score: 47.78  E-value: 4.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315   34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTmYNVNMMTWLLTSIMFTLILMIGLYHEWYNGML 113
Cdd:MTH00055  37 EKVSVYECGFDPFESSRIPFSVRFFLVGILFLIFDLEISFLFPWCVV-YNQIGLFGFWVMYLFLIILTIGLIYEWVKGGL 115


                 ..
gi 62161315  114 NW 115
Cdd:MTH00055 116 EW 117
ND3 MTH00030
NADH dehydrogenase subunit 3; Provisional
 34-115 3.86e-07

NADH dehydrogenase subunit 3; Provisional


Pssm-ID: 164603 [Multi-domain]  Cd Length: 123  Bit Score: 45.31  E-value: 3.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315   34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTMYNVNMMTWLLTsIMFTLILMIGLYHEWYNGML 113
Cdd:MTH00030  42 EKSSIYECGFDPFGKIRTPFTIKFVLVGILFMIFDIEISFLFPWSIVFNQLNLFSFWIV-YTFLIVLAIGLAYEWIKGGL 120


                 ..
gi 62161315  114 NW 115
Cdd:MTH00030 121 EW 122
NuoA COG0838
NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH: ...
 34-115 8.63e-07

NADH:ubiquinone oxidoreductase subunit 3 (chain A) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 3 (chain A) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440600 [Multi-domain]  Cd Length: 117  Bit Score: 43.96  E-value: 8.63e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315  34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIfdieiiiILPMILTMY----NVNMMTW--LLTSIMFTLILMIGLYHE 107
Cdd:COG0838  37 EKLSPYECGIEPVGDARIRFSVRYYLVALLFVI-------FDVEVVFLFpwavVFRELGWfgLIEMLVFIAILLVGLIYA 109


                ....*...
gi 62161315 108 WYNGMLNW 115
Cdd:COG0838 110 WKKGALEW 117
PRK06602 PRK06602
NADH:ubiquinone oxidoreductase subunit A; Validated
 35-116 1.92e-06

NADH:ubiquinone oxidoreductase subunit A; Validated


Pssm-ID: 180638 [Multi-domain]  Cd Length: 121  Bit Score: 43.31  E-value: 1.92e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315   35 KSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTmynVNMMTWL--LTSIMFTLILMIGLYHEWYNGM 112
Cdd:PRK06602  41 KNSPYESGFEAFGDARMKFDVRFYLVAILFVIFDLEAAFLFPWAVS---FREIGWLgfVEAMIFILVLLVGLVYLWRKGA 117


                 ....
gi 62161315  113 LNWA 116
Cdd:PRK06602 118 LDWE 121
ND3 MTH00018
NADH dehydrogenase subunit 3; Validated
 34-115 2.02e-06

NADH dehydrogenase subunit 3; Validated


Pssm-ID: 164592 [Multi-domain]  Cd Length: 113  Bit Score: 43.13  E-value: 2.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62161315   34 QKSTPFECGFNPISHKRLPFSIHFFLIAVLFLIFDIEIIIILPMILTmYNVNMMTWLLTSIMFTLILMIGLYHEWYNGML 113
Cdd:MTH00018  32 EKVSAYECGFDPFGFPGRPFSIRFFLIGILFLIFDLEISFLFPWCVL-YNQIAPFGFWTMVGFLFILTLGLIYEWIKGGL 110


                 ..
gi 62161315  114 NW 115
Cdd:MTH00018 111 EW 112
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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