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Conserved domains on  [gi|62184366|ref|YP_220717|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Balaenoptera bonaerensis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 5.15e-78

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 229.69  E-value: 5.15e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    1 MMTYIVFILSIVFVISFVGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366   81 EVWVSNKVVLGAFILGLVVEFLIVAYALKSGEVKIVFEFDGLGDWAVYGTGDSGVFSEEATGVAALYSYGVWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|....
gi 62184366  161 LFISVVIIMEITRG 174
Cdd:MTH00109 161 LFIGVFVIIEITRG 174
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 5.15e-78

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 229.69  E-value: 5.15e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    1 MMTYIVFILSIVFVISFVGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366   81 EVWVSNKVVLGAFILGLVVEFLIVAYALKSGEVKIVFEFDGLGDWAVYGTGDSGVFSEEATGVAALYSYGVWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|....
gi 62184366  161 LFISVVIIMEITRG 174
Cdd:MTH00109 161 LFIGVFVIIEITRG 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 3.84e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 44.42  E-value: 3.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    18 VGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKVVLGAFILGL 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 62184366    98 VVeFLIVAYALKSGEVKIVFEFDGLGDWAVYGTGdsgvfseeatgvAALYSYGVWLVIVTGWSLFISVVIIMEI 171
Cdd:pfam00499  81 LL-LALLLLVLLSASLTPAAAAAAPDVGNIEAIG------------ELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 5.15e-78

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 229.69  E-value: 5.15e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    1 MMTYIVFILSIVFVISFVGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366   81 EVWVSNKVVLGAFILGLVVEFLIVAYALKSGEVKIVFEFDGLGDWAVYGTGDSGVFSEEATGVAALYSYGVWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|....
gi 62184366  161 LFISVVIIMEITRG 174
Cdd:MTH00109 161 LFIGVFVIIEITRG 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 2-174 2.33e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 95.59  E-value: 2.33e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    2 MTYIVFILSIVFVISFVGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPE 81
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366   82 VWVSNKVVLGAFILGLVVEFLIVAYALKSGEvkivfefdglGDWA-VYGTGDSGVFSEEATGVAALYSYGVWLVIVTGWS 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYE----------GSWVvVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWV 150

                        170
                 ....*....|....
gi 62184366  161 LFISVVIIMEITRG 174
Cdd:MTH00138 151 LLLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 2-174 1.23e-23

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 91.06  E-value: 1.23e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    2 MTYIVFILSIVFVISFVGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPE 81
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366   82 VWVSNKVV--LGAFILGLVVEFLIVAyalksgevkivfEFDGLGDWAVYGTGDSGVFSEEATGVAALYSYGVWLVIVTGW 159
Cdd:MTH00065  81 AWGSWSVLvyVLFYLLLLIVGYILFG------------CNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGW 148

                        170
                 ....*....|....*
gi 62184366  160 SLFISVVIIMEITRG 174
Cdd:MTH00065 149 VLLLTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 2-175 6.03e-21

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 84.41  E-value: 6.03e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    2 MTYIVFILSIVFVISFVGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPE 81
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366   82 VWVSNKVVLGAFILGLVVEFLIVAYAlksgevkIVFEFDGLGDWAVYGTGDSGVfSEEATGVAALYSYGVWLVIVTGWSL 161
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVG-------GLWGMEGVGVVTVDSGGLFVV-RLDFSGVSLFYSSGGGGLLVCGWGL 152

                        170
                 ....*....|....
gi 62184366  162 FISVVIIMEITRGS 175
Cdd:MTH00115 153 LLTLFVVLELVRGL 166
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 2-174 1.69e-13

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 64.62  E-value: 1.69e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    2 MTYIVFILSIVFVISFVGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPE 81
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366   82 VWVSNKVVLGAFILGLVVEFlivayalksgevkiVFEFDGLGDWAVYGTGDSGVFSEEATGVAALYSYGVWLVIVTGWSL 161
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGF--------------VGFYFYGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVL 146

                        170
                 ....*....|...
gi 62184366  162 FISVVIIMEITRG 174
Cdd:MTH00214 147 FLVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-175 2.01e-10

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 56.45  E-value: 2.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    1 MMTYIVFILsIVFVISFVGVSSkpSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYP 80
Cdd:MTH00045   1 MVFYLFLIL-MLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366   81 EVWVSNKVVLGAFILGLVVEFLivayalksgevkivfeFDGLGDWAVYGTGDSGVFSEEatGVAALYSYGVWLVIVTGWS 160
Cdd:MTH00045  78 SVSNLGEVLVLSLLLSLWVFIS----------------FDNFLELSNNNWSLVSLSDLV--GSSELYNSGGLYLLLGGFI 139

                        170
                 ....*....|....*
gi 62184366  161 LFISVVIIMEITRGS 175
Cdd:MTH00045 140 LLVALVVALVISFGH 154
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 3.84e-06

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 44.42  E-value: 3.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62184366    18 VGVSSKPSPIYGGLGLIVGGGVGCGVVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEQYPEVWVSNKVVLGAFILGL 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 62184366    98 VVeFLIVAYALKSGEVKIVFEFDGLGDWAVYGTGdsgvfseeatgvAALYSYGVWLVIVTGWSLFISVVIIMEI 171
Cdd:pfam00499  81 LL-LALLLLVLLSASLTPAAAAAAPDVGNIEAIG------------ELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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