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Conserved domains on  [gi|66276088|ref|YP_238282|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Scleropages formosus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 535.54  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWT 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 MGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQIsQNTNPALLTTLGVM 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQI-APTNPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKST 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*..
gi 66276088  321 QITLPLTITIILTLMLLPVTPAITTMF 347
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPAILALL 346
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 535.54  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWT 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 MGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQIsQNTNPALLTTLGVM 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQI-APTNPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKST 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*..
gi 66276088  321 QITLPLTITIILTLMLLPVTPAITTMF 347
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPAILALL 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-296 2.41e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 2.41e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   8 TLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMA-QQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNI 86
Cdd:COG1007 106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNL 185

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  87 NQISHPLATTT------------VTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPAL- 153
Cdd:COG1007 186 AGIAAALAAGGanspllllglvlVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPGLa 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088 154 ------LTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPAL----TLLNLTIYITMTSTMFLSLKIMA 223
Cdd:COG1007 266 adwqllLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLLS 345

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 66276088 224 -----STKINSLA-LAWpKTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRL 296
Cdd:COG1007 346 rkggeAEEIEDLAgLAR-RSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 2.28e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 92.38  E-value: 2.28e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    23 SSHWLLAWMGLEINTMAIIPLMA-QQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNINQISHP--------- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKAltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    93 --LATTTVTLALALKIGLAPMHFWLPEVLQGLNLT-TGLVLSTWQKLAPFALI-----LQISQNTNPALLTTLGVMSALV 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   165 GGWGGLNQTQLRKLLAYSSIAHLGWMIIIL----QFMPALTLLNLTIYITMTSTMFL-----SLKIMASTKINSLALAWP 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 66276088   236 KTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-296 1.49e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 92.32  E-value: 1.49e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088     6 LTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMA-QQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDW 84
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    85 NINQISHPLATTTVT------------LALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQIS------ 146
Cdd:TIGR01770 184 NFEDLLLFLSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   147 -QNTNPALLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQF-----MPALtLLNLTIYITMTSTMFLSLK 220
Cdd:TIGR01770 264 fSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAgtlegIKAV-LFYIFIYALMSLGAFGVLS 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   221 IMASTK------INSLALAWPKTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYL 294
Cdd:TIGR01770 343 LLRSYKdewieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYL 422


                  ..
gi 66276088   295 RL 296
Cdd:TIGR01770 423 RV 424
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 535.54  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWT 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 MGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQIsQNTNPALLTTLGVM 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQI-APTNPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKST 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*..
gi 66276088  321 QITLPLTITIILTLMLLPVTPAITTMF 347
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPAILALL 346
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-347 9.22e-143

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 407.77  E-value: 9.22e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWT 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 MGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPALLTTLGVM 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKsT 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK-N 319

                        330       340
                 ....*....|....*....|....*..
gi 66276088  321 QITLPLTITIILTLMLLPVTPAITTMF 347
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNLF 346
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-347 1.48e-126

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 366.46  E-value: 1.48e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWT 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 MGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPALLTTLGVM 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKST 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*..
gi 66276088  321 QITLpLTITIILTLMLLPVTPAITTMF 347
Cdd:MTH00112 321 KNTL-TATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 9.27e-123

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 356.85  E-value: 9.27e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWT 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 MGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPALLTTLGVM 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKST 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 66276088  321 QITLPLTITIILTLMLLPVTPAITTMF 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 5.06e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 324.61  E-value: 5.06e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWT 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 MGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPALLTTLGVM 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKST 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*..
gi 66276088  321 qITLPLTITIILTLMLLPVTPAITTMF 347
Cdd:MTH00200 321 -SNLLVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-337 1.59e-88

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 269.88  E-value: 1.59e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWT 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 MGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPALLTTLGVM 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKST 320
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330
                 ....*....|....*..
gi 66276088  321 QITLPLTITIILTLMLL 337
Cdd:MTH00041 321 ITVYGVILSILSSISIL 337
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-338 1.89e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 178.86  E-value: 1.89e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    1 MNPYVLTTLILsLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAwt 80
Cdd:MTH00160   3 MNSSKLLFLST-LIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNM-- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   81 mgdwNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTnpaLLTTLGVM 160
Cdd:MTH00160  80 ----LNLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNN---FIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  241 TTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKST 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFS 312

                        330
                 ....*....|....*...
gi 66276088  321 QITLPLTITIILTLMLLP 338
Cdd:MTH00160 313 LILNFLSFISLFGLILSS 330
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-337 2.99e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 167.76  E-value: 2.99e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   13 LGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNInqishp 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS------ 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   93 laTTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPA-LLTTLGVMSALVGGWGGLN 171
Cdd:MTH00144  87 --MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAyLLCVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  172 QTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTlTTLIMLSLLSL 251
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKT-GLSIISLLLSL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  252 GGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKSTqITLPLTITII 331
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSI-ISLNLLGGLL 322


                 ....*.
gi 66276088  332 LTLMLL 337
Cdd:MTH00144 323 FLLLYL 328
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 12-333 3.39e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 159.95  E-value: 3.39e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   12 SLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMgdwniNQISH 91
Cdd:MTH00011  14 TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFP-----SLLKN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   92 PLATTtVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPALLTTLGVMSALVGGWGGLN 171
Cdd:MTH00011  89 ITALM-LLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMN 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  172 QTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTLTTLIMLSLLSL 251
Cdd:MTH00011 168 QTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSL 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  252 GGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCYTTTLTTFPNTNNTTSPWRLKSTQITLPLTITII 331
Cdd:MTH00011 248 GGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSPTFSSLKSAPYEPKTKILISMCTLSLG 327


                 ..
gi 66276088  332 LT 333
Cdd:MTH00011 328 LI 329
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 15-298 3.91e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 138.65  E-value: 3.91e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   15 LGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFAstmNAWTMGDWNINQISHPLa 94
Cdd:MTH00197   9 GGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMG---GSLSFSNLYLSLLSVVL- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   95 tttVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQIsqNTNPALLTTLGVMSALVGGWGGLNQTQ 174
Cdd:MTH00197  85 ---VILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFN--SSSFMGLLICSVLSSLIGGIGGMNQSN 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  175 LRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYITMTSTMFLSLKIMASTKINSLALAWPKTPTLTTLIMLSLLSLGGL 254
Cdd:MTH00197 160 IRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGL 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 66276088  255 PPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCY 298
Cdd:MTH00197 240 PPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-296 2.41e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 103.27  E-value: 2.41e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   8 TLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMA-QQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNI 86
Cdd:COG1007 106 ALLLFATLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNL 185

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  87 NQISHPLATTT------------VTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPAL- 153
Cdd:COG1007 186 AGIAAALAAGGanspllllglvlVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPGLa 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088 154 ------LTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPAL----TLLNLTIYITMTSTMFLSLKIMA 223
Cdd:COG1007 266 adwqllLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLLS 345

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 66276088 224 -----STKINSLA-LAWpKTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRL 296
Cdd:COG1007 346 rkggeAEEIEDLAgLAR-RSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 15-296 2.86e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 96.25  E-value: 2.86e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   15 LGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHP-RATEATTKYFLTQATAAAMILFASTMNAWTMGDWNIN------ 87
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSyinlvl 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   88 -------QISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNpaLLTTLGVM 160
Cdd:MTH00196  84 nsgqsfsSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGGLF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  161 SALVGGWGGLNQTQLRKLLAYSSIAHLG---WMIIILQFMPALT-LLNLTIYITMTSTMFLSLKIMASTK--INSLALAW 234
Cdd:MTH00196 162 SLFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFESIQAsLVYLFIYIIMSICVFSIILALNVYKnlIIEFSGLS 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 66276088  235 PKTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRL 296
Cdd:MTH00196 242 RRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-268 2.28e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 92.38  E-value: 2.28e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    23 SSHWLLAWMGLEINTMAIIPLMA-QQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNINQISHP--------- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKAltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    93 --LATTTVTLALALKIGLAPMHFWLPEVLQGLNLT-TGLVLSTWQKLAPFALI-----LQISQNTNPALLTTLGVMSALV 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   165 GGWGGLNQTQLRKLLAYSSIAHLGWMIIIL----QFMPALTLLNLTIYITMTSTMFL-----SLKIMASTKINSLALAWP 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 66276088   236 KTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQ 268
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 9-296 2.60e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 94.31  E-value: 2.60e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    9 LILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMA-QQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNIN 87
Cdd:MTH00199 102 LILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQ 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   88 QISHPLATTT----VTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPALLTtlGVMSAL 163
Cdd:MTH00199 182 GINSILTGDVgkilITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSII 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  164 VGGWGGLNQTQLRKLLAYSSIAHLGWMII---ILQFMP-ALTLLNLTIYITMTSTMF---LSLKIMASTKINSLALAwPK 236
Cdd:MTH00199 260 YGAIGALNQTKIKRLLAYSGIGHMGFILFgvaIGSFESiQASLIYMIIYVIMSICSFsiiLSLKLTKGLIVEVSGLS-RK 338

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  237 TPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRL 296
Cdd:MTH00199 339 NPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-296 1.49e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 92.32  E-value: 1.49e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088     6 LTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMA-QQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDW 84
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    85 NINQISHPLATTTVT------------LALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQIS------ 146
Cdd:TIGR01770 184 NFEDLLLFLSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   147 -QNTNPALLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQF-----MPALtLLNLTIYITMTSTMFLSLK 220
Cdd:TIGR01770 264 fSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAgtlegIKAV-LFYIFIYALMSLGAFGVLS 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   221 IMASTK------INSLALAWPKTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYL 294
Cdd:TIGR01770 343 LLRSYKdewieyISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYL 422


                  ..
gi 66276088   295 RL 296
Cdd:TIGR01770 423 RV 424
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-296 4.60e-19

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 87.95  E-value: 4.60e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    8 TLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMA-QQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNI 86
Cdd:PRK05777 107 LLVLFALLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSF 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   87 NQISHPLATTT------------VTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQNTNPAL- 153
Cdd:PRK05777 187 AGIAKALADGSgnsllllfglvfLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLLVVAFGGLs 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  154 ------LTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIIL----QFMPALTLLNLTIYITMTSTMFLSLKIMA 223
Cdd:PRK05777 267 edwqqvLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLaagtAEGYSAVLFYLLAYLFMTLGAFGVISLLR 346

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 66276088  224 S-----TKINSLA-LAWpKTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRL 296
Cdd:PRK05777 347 RkggeaESISDFAgLSK-RSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 8-296 2.94e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 82.12  E-value: 2.94e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   8 TLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNIN 87
Cdd:COG0651 111 PLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMA 190

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  88 QISHPLA---TTTVTLALAL-------KIGLAPMHFWLPE-----------VLQGLNLTTGL--VLSTWQKLAPFALILQ 144
Cdd:COG0651 191 DLAARLAeldPGLLLAAFALllvgfgiKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALF 270

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088 145 ISQntnpaLLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYI----TMTSTMFLS-- 218
Cdd:COG0651 271 LGT-----LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFLAag 345

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088 219 --LKIMASTKINSLALAWPKTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRL 296
Cdd:COG0651 346 aiERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-192 2.56e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 76.82  E-value: 2.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    9 LILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRAT---------EATTKYFLTQATAAAMILFA------ 73
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGcalyfg 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   74 --------STMNAWTMGDWNINQISHPLATTTVTLALALKIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFalILQI 145
Cdd:MTH00198 273 ftgnegmlGTILSATLETTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVY--ILLT 350

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 66276088  146 SQNTNPALLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMII 192
Cdd:MTH00198 351 SLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILI 397
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-263 3.51e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 57.75  E-value: 3.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   50 PRATEATTKYFLTQATAAAMILF-ASTMNAWTMGDWNINQISHPLAT-TTVTLALAL---------KIGLAPMHFWLPEV 118
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSAIALALITsPSLGLALALvfviagiafKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  119 LQGLNLTTGLVLSTWQKLAPFALILQISQNTNPA-------LLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMI 191
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPSfdeqwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  192 IIL----QFMPALTLLNLTIYITMTSTMFL-----SLKiMASTKINSLALAWPKTPTLTTLIMLSLLSLGGLPPLTGFMP 262
Cdd:PRK02504 317 IGLvagtEAGYASMVFYLLAYLFMNLGAFAcvilfSLR-TGTDQISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFG 395


                 .
gi 66276088  263 K 263
Cdd:PRK02504 396 K 396
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-298 3.53e-09

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 57.97  E-value: 3.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   33 LEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNINQIS------HPLATTT--VTLALAL 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAgalaenPTVVTAFgfVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  105 KIGLAPMHFWLPEVLQGLNLTTGLVLS-TWQKLAPFALIL------QISQNTNPALLT---TLGVMSALVGGWGGLNQTQ 174
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIRiyftvfGGDFRFALGLGWllaVLALLSMLVGSLAALGQDD 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  175 LRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYI----TMTSTMFLSLKIMAST----KINSLALAWPKTPTLTTLIML 246
Cdd:PRK08375 295 VKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLlhhaLMKGALFLAAGAIEVTygtrRLSELSGLGRRMPLTAAAFAV 374

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 66276088  247 SLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCY 298
Cdd:PRK08375 375 ASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 44-298 1.12e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 56.52  E-value: 1.12e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   44 MAQQHHPRATEATTKYFLTQATAAAMILFA--------STMN-----AWTMGDWNINQIS---HPLATTTVTLALAL--- 104
Cdd:PRK12667 154 AYYRDRGDAVEAAIKYALIGAVGTTLYFLAlaflyatfGTLNmadlsAKIRGLSFPLTGGlagNPPLALGVALALALwaf 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  105 --KIGLAPMHFWLPEV-----------LQGLNLTTG---------LVLSTWQKLAPFALILQIsqntnpaLLTTLGVMSA 162
Cdd:PRK12667 234 tiKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAALSP-------ILIILGAVSA 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  163 LVGGWGGLNQTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYIT----MTSTMFLS----LKIMASTKINSLALAW 234
Cdd:PRK12667 307 IIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaiAKSLLFLAsgvfIHAAGTRDIDELAGLG 386

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 66276088  235 PKTPTLTTLIMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCY 298
Cdd:PRK12667 387 RKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWY 450
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-192 1.55e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 55.87  E-value: 1.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   33 LEINTMAIIPLMAQQHH-PRATEATTKYFLTQATAAAMILFASTM-----NAWTMGDWNINQISHPLATTTVTLA----- 101
Cdd:PRK08376 150 LEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGIALlygqyGTLNMAYLAVKMSENPTVVAKIALAlfiag 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  102 LALKIGLAPMHFWLPEVLQGL--NLTTGLVLSTWQKLAPFALIL------QISQNTNPALLTTLGVMSALVGGWGGLNQT 173
Cdd:PRK08376 230 LAMKSGAVPVHMWLPDAYPAApsSISAMLLVIKQAGLYALARVLfsiygpAINLATVGWVIIILGCLTMFVGVAMAVVQK 309

                        170
                 ....*....|....*....
gi 66276088  174 QLRKLLAYSSIAHLGWMII 192
Cdd:PRK08376 310 DVKRLLAYHSVSQIGYMLL 328
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
9-192 1.05e-06

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 50.08  E-value: 1.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    9 LILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWN--- 85
Cdd:PRK06473 112 LLLLLNAGVSGAFLAQDLLLFFLFYELELIPLYLLIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGASSfdy 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   86 --INQISHPLATTTVTLA-----LALKIGLAPMHFWLPE-----------VLQG--LNLTT--------GLVLSTWQKLA 137
Cdd:PRK06473 192 epLRSHTLPLSTQLLLLApilvgFGIKIPLVPFHTWLPDahveastpvsvLLAGvlLKLGTygllrfgvGLFPEAWVYLA 271

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 66276088  138 PFalilqisqntnpalLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMII 192
Cdd:PRK06473 272 PW--------------LATWAVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILL 312
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 19-190 2.50e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 45.69  E-value: 2.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   19 LTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFAST---MNAWT-MGD------W-NIN 87
Cdd:PRK06458 123 LALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTIlvyANAATvMGDgemailWtELL 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   88 QISHPLATTTVTLALAL-------KIGLAPMHFWLPE-----------VLQGLNLTTGLVLstwqkLAPFALILQISQNT 149
Cdd:PRK06458 203 KHASLLDPTLMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYA-----VLRYYILIDAAIGS 277

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 66276088  150 NPA--LLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWM 190
Cdd:PRK06458 278 DFPgrLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 51-298 2.57e-05

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 45.76  E-value: 2.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   51 RATEATTKYFLTQATAAAMILFASTMNAWTMGDWNINQISHPLATTTVT---LALAL--------KIGLAPMHFWLPEVL 119
Cdd:PRK08668 144 ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADISQGLINDTSTgfaLIVFLfllafgvaKAGIFPLHVWAPDAY 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  120 QGLNLTTGLVLS-TWQKLAPFALILQI----------------SQNTNPALLTTLGVMSALVGGWGGLNQTQLRKLLAYS 182
Cdd:PRK08668 224 SEAPQSFSAVLSgQLSKLGAYGFLLVLyvlpgtklfsefgtyrGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYS 303

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  183 SIAHLGWMIIILQFMPALTLLNLTIYI----TMTSTMFLSLKIMA----STKINSL-ALAWpKTPTLTTLIMLSLLSLGG 253
Cdd:PRK08668 304 SVANGGYILVGLGLGTSLGFAGGLFHVfnhaLFKGLFFLIFAAVIyrtgTTKISEMgGLIE-KMPFTFAMYLVAIISLAG 382

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 66276088  254 LPPLTGFMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRLCY 298
Cdd:PRK08668 383 IPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 100-298 2.94e-05

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 45.70  E-value: 2.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   100 LALALKIGLAPMHFWLPEVlQGLNLTTGLVL--STWQKLAPFALI---LQISQNTNPA---LLTTLGVMSALVGGWGGLN 171
Cdd:TIGR01972 211 IAFAVKVPLFPLHTWLPDA-HVEAPTAGSVIlaGVLLKMGTYGFLrfnLPLFPDASLYfapVLAALGVIAIIYGALIALA 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   172 QTQLRKLLAYSSIAHLGWMIIILQFMPALTLLNLTIYI----TMTSTMFLSLKI----MASTKINSLALAWPKTPTLTTL 243
Cdd:TIGR01972 290 QTDIKRLIAYSSISHMGFVLLGIFSFNELGISGAVFQMishgLITAALFLLVGVlyerAHTRDIAKYGGLANKMPVLAAF 369

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 66276088   244 IMLSLLSLGGLPPLTGFMPKWLILQELAKQDLPIT---ATIMAMSALLSLFFYLRLCY 298
Cdd:TIGR01972 370 FMLFAMASLGLPGTSGFVGEFLILLGSFKVNPVVAflaALGIVLAAAYMLTLYKRVFF 427
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-192 6.67e-05

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 44.69  E-value: 6.67e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  49 HPRATEATTKYFLTQATAAAMILFASTMNAWTMGDW--NINQIS-HPLATTTVTL-------ALALKIGLAPMHFWLPE- 117
Cdd:COG1008 156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAaAPLPLTAQLLlflaffiAFAVKVPMFPFHTWLPDa 235

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088 118 ----------VLQGLNLTTG----------LVLSTWQKLAPFALILqisqntnpallttlGVMSALVGGWGGLNQTQLRK 177
Cdd:COG1008 236 hveaptagsvLLAGVLLKMGgygllrfalpLFPEASAYFAPLLAAL--------------GVIGIIYGALVALAQTDLKR 301

                       170
                ....*....|....*
gi 66276088 178 LLAYSSIAHLGWMII 192
Cdd:COG1008 302 LIAYSSVSHMGFVLL 316
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 1.11e-04

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 39.16  E-value: 1.11e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 66276088   291 FFYLRLCYTTTLTTFPNTNNTTSPWRLKSTQITLPLTITIILTLMLLPVTP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-194 1.47e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 43.37  E-value: 1.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   98 VTLALALKIGLAPMHFWLPEV-----LQGLNLTTGLVLstwqKLAPFAL------ILQI-SQNTNPALLTtLGVMSALVG 165
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILL----KLGGYGLvrlswpILPLgAQNLAPAVIA-MGIVGIVYG 310

                         90       100
                 ....*....|....*....|....*....
gi 66276088  166 GWGGLNQTQLRKLLAYSSIAHLGWMIIIL 194
Cdd:MTH00226 311 SFATCRQIDVKRLVAYSSVAHMGLVSITL 339
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 9-192 5.02e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 41.94  E-value: 5.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    9 LILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDWNINQ 88
Cdd:PRK12561  92 LMLVLYSAQIGVFLAQDLLLFFLMWELELVPVYLLISIWGGQKRLYAATKFILYTALASIFILVAGLALALSGDTFTFDL 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   89 ISHPLATTTVTLALALKIGLA----------PMHFWLPEVLQGLNLTTGLVLS-TWQKLAPFALI---LQISQNTN---- 150
Cdd:PRK12561 172 AELGAKSYPLALELLLYAGFLiafgvklpifPLHTWLPDAHGEASAPVSMILAgVLLKMGGYALIrfnVQMLPDAHvyfa 251

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 66276088  151 PALLTtLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMII 192
Cdd:PRK12561 252 PALAI-LGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLL 292
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
3-192 6.68e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 41.24  E-value: 6.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088    3 PYVLTTLILSLGLGTTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMG 82
Cdd:PRK07363 106 PRLYYSLILLINGGIAGALLAQNLLLFFLFYELELIPFYLLIAIWGGEKRGYASIKFLIYTAVSGLLVLAAFLGIVWLSG 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   83 DWN-----INQISHPLATTTVTLALAL-----KIGLAPMHFWLPEVLQGLNLTTGLVLS-TWQKLAPFALI---LQI--- 145
Cdd:PRK07363 186 STSfdydaISTQNLSLNTQLILLTGLLlgfgiKIPLVPLHTWLPDAYTEASPAVAILLGgVLAKLGTYGLLrfgLQLfpq 265

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 66276088  146 SQNTNPALLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMII 192
Cdd:PRK07363 266 TWSLVAPGLAIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYILV 312
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 67-194 7.34e-04

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 41.29  E-value: 7.34e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  67 AAMILFASTMNAWTMGDWnINQISHPLATTTVTLALAL-------KIGLAPMHFWLPEVLQGLN-----------LTTGL 128
Cdd:COG1009 180 LGILLLGAIAGTLNFSEL-LAAAPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDAMEGPTpvsallhaatmVKAGV 258

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 66276088 129 VLstwqkLAPFALILQISQNTNPaLLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIIL 194
Cdd:COG1009 259 YL-----LARLSPLFALSPVWLT-VVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-296 8.30e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 41.14  E-value: 8.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   51 RATEATTKYFLTQATAAAMILFA-STMNAWTMGDWNINQISHPLATTT-------------VTLALALKIGLAPMHFWLP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGfSWLYGLSGGEIELQEIVNGLINTQmynspgisialifITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  117 EVLQGLNLTTGLVLSTWQKLAPFAL-------ILQISQNTNPALLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAASALatrifdiPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  190 MII-ILQFMP----ALTLLNLTIYITMTSTMF-----LSLKiMASTKINSLALAWPKTPTLTTLIMLSLLSLGGLPPLTG 259
Cdd:CHL00049 319 VIIgIIVGDSndgyASMITYMLFYIFMNLGTFacivlFGLR-TGTDNIRDYAGLYTKDPFLALSLALCLLSLGGIPPLAG 397

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 66276088  260 FMPKWLILQELAKQDLPITATIMAMSALLSLFFYLRL 296
Cdd:CHL00049 398 FFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK12650 PRK12650
DUF4040 family protein;
91-191 1.09e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 40.80  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   91 HPLATTTVTLALAL----KIGLAPMHFWLPEVLQGLNLTTGLVLSTWQKLAPFALILQISQ--NTNPA---LLTTLGVMS 161
Cdd:PRK12650 203 KPGLTTVVAVLIAVaaftKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPvfHDVAVwnwLLIIVGMIT 282

                         90       100       110
                 ....*....|....*....|....*....|
gi 66276088  162 ALVGGWGGLNQTQLRKLLAYSSIAHLGWMI 191
Cdd:PRK12650 283 ALMGAVFAVQKTDLKKLTAYSTVSQLGWIV 312
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-192 3.53e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 39.03  E-value: 3.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   55 ATTKYFL-TQATAAAM---ILFASTMNAWTMGDWNINQI-SHPLATTTVTL-------ALALKIGLAPMHFWLPEV---- 118
Cdd:PRK05846 162 AATKFFLyTLLGSLLMlvaIIYLVVVYYNATGTFDIADLlNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPDAhvqa 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  119 -LQGLNLTTGLVLstwqKLAPFALI---LQI----SQNTNPaLLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWM 190
Cdd:PRK05846 242 pTAGSVLLAGILL----KMGAYGLLrfsLPLfpdaSHEFAP-IIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFV 316


                 ..
gi 66276088  191 II 192
Cdd:PRK05846 317 TL 318
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 82-194 3.54e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 39.14  E-value: 3.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   82 GDWNINQI-SHPLATTTVTLALAL-------KIGLAPMHFWLPE-----------------VLQGLNLTTGL-----VLS 131
Cdd:PRK12644 185 GTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGamaaptpvsaylhaaamVKAGIYLVARLapgfaDVP 264

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 66276088  132 TWQklapfalilqisqntnPALLTtLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMIIIL 194
Cdd:PRK12644 265 VWR----------------PTVLV-LGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-192 4.38e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 38.97  E-value: 4.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   17 TTLTFASSHWLLAWMGLEINTMAIIPLMAQQHHPRATEATTKYFLTQATA------AAMILFASTMNAWTMG--DWNINQ 88
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNWTELA 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   89 ISHPLATTTVTLA--------LALKIGLAPMHFWLPE-----------VLQGLNLTTGLVlstwQKLAPFALILQIS-QN 148
Cdd:PRK08676 195 AHASLLSPSVLGAsflfifigFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGIY----GILRLSALLRQSGaAE 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 66276088  149 TNPALLTTLGVMSALVGGWGGLNQTQLRKLLAYSSIAHLGWMII 192
Cdd:PRK08676 271 QFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLL 314
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 44-206 5.40e-03

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 38.72  E-value: 5.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088   44 MAQQHHPRATEATTKYFLTQATAAAMILFASTMNAWTMGDW---NINQISHPLATTTVTLALAL-----KIGLAPMHFWL 115
Cdd:PRK06521 154 IANHREAEIRRAGFLYLLMAHAGALAILLAFGLLARESGSYdfaAMRAAHLSPFWASLVFLLALfgfgaKAGLVPLHVWL 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66276088  116 PEVLQGL-----NLTTGLVLstwqKLAPFALI------LQISQNTNPALLTTLGVMSALVGGWGGLNQTQLRKLLAYSSI 184
Cdd:PRK06521 234 PRAHPAApshvsALMSGVML----KVAIYGILrvvfdlLGAPGWWWGVLVLALGAISAVLGVLYALAEHDLKRLLAYSTI 309

                        170       180       190
                 ....*....|....*....|....*....|
gi 66276088  185 AHLGW--------MIIILQFMPALTLLNLT 206
Cdd:PRK06521 310 ENIGIifvglglaMVFIAYGMPLLAALALT 339
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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