NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|38788445|ref|NP_000522|]
View 

ornithine transcarbamylase, mitochondrial precursor [Homo sapiens]

Protein Classification

ornithine carbamoyltransferase( domain architecture ID 11414683)

ornithine carbamoyltransferase reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to L-ornithine (ORN) to produce L-citrulline, as part of the urea cycle and L-arginine biosynthesis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 35-342 2.41e-161

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


:

Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 453.35  E-value: 2.41e-161
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  35 VQLKGRDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQ 114
Cdd:COG0078   1 TNLKGRHFLSLLDLTPEELRALLDLAAELK-AKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445 115 DIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWI 194
Cdd:COG0078  80 DSQLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYV 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445 195 GDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEK 274
Cdd:COG0078 160 GDGNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAEAVKGADVVYTDVWVSMGQEEEA 239

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 38788445 275 KKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:COG0078 240 EERIKAFKPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVFDEAENRLHAQKALLAWLL 308
 
Name Accession Description Interval E-value
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 35-342 2.41e-161

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 453.35  E-value: 2.41e-161
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  35 VQLKGRDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQ 114
Cdd:COG0078   1 TNLKGRHFLSLLDLTPEELRALLDLAAELK-AKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445 115 DIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWI 194
Cdd:COG0078  80 DSQLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYV 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445 195 GDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEK 274
Cdd:COG0078 160 GDGNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAEAVKGADVVYTDVWVSMGQEEEA 239

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 38788445 275 KKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:COG0078 240 EERIKAFKPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVFDEAENRLHAQKALLAWLL 308
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
 36-342 3.48e-156

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 440.30  E-value: 3.48e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   36 QLKGRDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQD 115
Cdd:PRK00779   1 MLMGRHFLSLDDLSPEELEELLDLAAELK-KKRKAGEPHPPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIFLSPRD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  116 IHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIG 195
Cdd:PRK00779  80 TQLGRGEPIEDTARVLSRYVDAIMIRTFEHETLEELAEYSTVPVINGLTDLSHPCQILADLLTIYEHRGSLKGLKVAWVG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  196 DGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVtklAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKK 275
Cdd:PRK00779 160 DGNNVANSLLLAAALLGFDLRVATPKGYEPDPEI---VEKIAKETGASIEVTHDPKEAVKGADVVYTDVWVSMGQEAEAE 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 38788445  276 KRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PRK00779 237 ERLKAFAPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVWDEAENRLHAQKALLAWLL 304
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
 40-342 3.58e-148

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 419.83  E-value: 3.58e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445    40 RDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLG 119
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLK-KGKKKGKEHKKLKGKTLALIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   120 VNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNN 199
Cdd:TIGR00658  80 RGESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGKLKGVKVVYVGDGNN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   200 ILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQ 279
Cdd:TIGR00658 160 VCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELTHDPVEAVKGADVIYTDVWVSMGEEDKKEERLK 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 38788445   280 AFQGYQVTMKTAKVAASDWTFLHCLPR-KPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:TIGR00658 240 LFRPYQVNEELMELAKPEVIFMHCLPAhRGEEVTDEVIEGPHSIVFDQAENRLHAQKAVMVALL 303
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
41-181 3.71e-66

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 205.35  E-value: 3.71e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445    41 DLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGV 120
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELK-EARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSS 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 38788445   121 NESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQE 181
Cdd:pfam02729  80 GESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
 
Name Accession Description Interval E-value
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 35-342 2.41e-161

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 453.35  E-value: 2.41e-161
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  35 VQLKGRDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQ 114
Cdd:COG0078   1 TNLKGRHFLSLLDLTPEELRALLDLAAELK-AKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445 115 DIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWI 194
Cdd:COG0078  80 DSQLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYV 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445 195 GDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEK 274
Cdd:COG0078 160 GDGNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAEAVKGADVVYTDVWVSMGQEEEA 239

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 38788445 275 KKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:COG0078 240 EERIKAFKPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVFDEAENRLHAQKALLAWLL 308
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
 36-342 3.48e-156

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 440.30  E-value: 3.48e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   36 QLKGRDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQD 115
Cdd:PRK00779   1 MLMGRHFLSLDDLSPEELEELLDLAAELK-KKRKAGEPHPPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIFLSPRD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  116 IHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIG 195
Cdd:PRK00779  80 TQLGRGEPIEDTARVLSRYVDAIMIRTFEHETLEELAEYSTVPVINGLTDLSHPCQILADLLTIYEHRGSLKGLKVAWVG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  196 DGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVtklAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKK 275
Cdd:PRK00779 160 DGNNVANSLLLAAALLGFDLRVATPKGYEPDPEI---VEKIAKETGASIEVTHDPKEAVKGADVVYTDVWVSMGQEAEAE 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 38788445  276 KRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PRK00779 237 ERLKAFAPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVWDEAENRLHAQKALLAWLL 304
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
 40-342 3.58e-148

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 419.83  E-value: 3.58e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445    40 RDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLG 119
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLK-KGKKKGKEHKKLKGKTLALIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   120 VNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNN 199
Cdd:TIGR00658  80 RGESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGKLKGVKVVYVGDGNN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   200 ILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQ 279
Cdd:TIGR00658 160 VCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELTHDPVEAVKGADVIYTDVWVSMGEEDKKEERLK 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 38788445   280 AFQGYQVTMKTAKVAASDWTFLHCLPR-KPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:TIGR00658 240 LFRPYQVNEELMELAKPEVIFMHCLPAhRGEEVTDEVIEGPHSIVFDQAENRLHAQKAVMVALL 303
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
 35-344 4.23e-132

ornithine carbamoyltransferase; Validated


Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 380.39  E-value: 4.23e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   35 VQLKGRDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQ 114
Cdd:PRK02102   3 FNLKGRSFLKLLDFTPEEIEYLIDLSIELK-AAKKAGIEHQYLEGKNIALIFEKTSTRTRCAFEVAAIDLGAHVTYLGPN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  115 DIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWI 194
Cdd:PRK02102  82 DSQLGKKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDEWHPTQMLADFMTMKEHFGPLKGLKLAYV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  195 GDG-NNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEE 273
Cdd:PRK02102 162 GDGrNNMANSLMVGGAKLGMDVRICAPKELWPEEELVALAREIAKETGAKITITEDPEEAVKGADVIYTDVWVSMGEEDE 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  274 KKKRLQAFQGYQVTMKTAKVAA-SDWTFLHCLP------------------RKPEEVDDEVFYSPRSLVFPEAENRKWTI 334
Cdd:PRK02102 242 WEERIKLLKPYQVNMDLMKATGnPDVIFMHCLPafhdtetkvgkeiaekygLKGLEVTDEVFESKYSIVFDEAENRMHTI 321

                        330
                 ....*....|
gi 38788445  335 MAVMVSLLTD 344
Cdd:PRK02102 322 KAVMVATLGD 331
PLN02342 PLN02342
ornithine carbamoyltransferase
 34-342 5.10e-132

ornithine carbamoyltransferase


Pssm-ID: 177976 [Multi-domain]  Cd Length: 348  Bit Score: 380.67  E-value: 5.10e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   34 KVQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGE-YLPLlQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLT 112
Cdd:PLN02342  40 KGKSKPKHFLHIDDFDKEEILGLLDRAKEVKALLKSGDRsFQPF-KGKSMAMIFTKPSMRTRVSFETGFFLLGGHALYLG 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  113 TQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLS 192
Cdd:PLN02342 119 PDDIQLGKREETRDIARVLSRYNDIIMARVFAHQDVLDLAEYSSVPVINGLTDYNHPCQIMADALTIIEHIGRLEGTKVV 198

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  193 WIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTklaeQYAKENGT-KLLLTNDPLEAAHGGNVLITDTWISMGQE 271
Cdd:PLN02342 199 YVGDGNNIVHSWLLLAAVLPFHFVCACPKGYEPDAKTV----EKARAAGIsKIEITNDPAEAVKGADVVYTDVWASMGQK 274

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 38788445  272 EEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPE-EVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PLN02342 275 EEAEKRKKAFQGFQVNEALMKLAGPQAYFMHCLPAERGvEVTDGVMEAPNSIVFPQAENRMHAQNAIMLHQL 346
putr_carbamoyl TIGR04384
putrescine carbamoyltransferase; Members of this family are putrescine carbamoyltransferase ...
 41-348 3.25e-99

putrescine carbamoyltransferase; Members of this family are putrescine carbamoyltransferase (EC 2.1.3.6). There is some overlapping specificity with ornithine carbamoyltransferase (EC 2.1.3.3). The gene regularly is found next to agmatine deiminase and a carbamate kinase, suggesting a conserved catabolic agmatine deiminase pathway. [Energy metabolism, Amino acids and amines]


Pssm-ID: 275177  Cd Length: 330  Bit Score: 296.56  E-value: 3.25e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445    41 DLLTLKNFTGEEIKYMLWLSADLKFRIKQkGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGV 120
Cdd:TIGR04384   1 DFIDTNDFTKEEILDIIDLSLKIKEAIKD-GYYPPLLKNKSLGMIFEQSSTRTRVSFETAMTQLGGHAQYLAPGQIQLGG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   121 NESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGL---TLSWIGDG 197
Cdd:TIGR04384  80 HESIEDTARVLSRLVDIIMARVDRHETVVELAKYATVPVINGMSDYNHPTQELGDLFTMIEHLPAGKKLedcKVVFVGDA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   198 NNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISM-GQEEEKKK 276
Cdd:TIGR04384 160 TQVCVSLMFICTKMGMDFVHFGPKGYQIPEEWLAIAEANCKVSGGSVTVTDDVDEAVKGADFIYTDVWYGLyDQELSEEE 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 38788445   277 RLQAFQ-GYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPQ 348
Cdd:TIGR04384 240 RMAIFYpKYQVNPELMAKAGPHAKFMHCLPaSRGEEVTDEVMDSPQSICFDEAENRLTAIRALLVYFLYPRLKP 313
PRK14805 PRK14805
ornithine carbamoyltransferase; Provisional
 40-343 1.35e-97

ornithine carbamoyltransferase; Provisional


Pssm-ID: 237819 [Multi-domain]  Cd Length: 302  Bit Score: 291.59  E-value: 1.35e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   40 RDLLTLKNFTGEEIKYMLWLSADLKfriKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLG 119
Cdd:PRK14805   2 KHLLSIKELTQQQLLDLLALAKTIK---ANPAEYRQALAGKSVVMLFEKPSLRTRVSFDIGINKLGGHCLYLDQQNGALG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  120 VNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNN 199
Cdd:PRK14805  79 KRESVADFAANLSCWADAIVARVFSHSTIEQLAEHGSVPVINALCDLYHPCQALADFLTLAEQFGDVSKVKLAYVGDGNN 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  200 ILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDpLEAAHGGNVLITDTWISMGQEEEKKKRLQ 279
Cdd:PRK14805 159 VTHSLMYGAAILGATMTVICPPGHFPDGQIVAEAQELAAKSGGKLVLTSD-IEAIEGHDAIYTDTWISMGDDTPLAEIKA 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 38788445  280 AFQGYQVTMK-TAKVAASdwTFLHCLPRKPE-EVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLT 343
Cdd:PRK14805 238 KFAPYQVNKAlMEKAGAT--FVMHCQPAHRGvEITSEVMDGEGSLILQQAENRMHAQNAVLVTLLS 301
PRK04284 PRK04284
ornithine carbamoyltransferase; Provisional
 37-344 1.24e-92

ornithine carbamoyltransferase; Provisional


Pssm-ID: 235269 [Multi-domain]  Cd Length: 332  Bit Score: 280.09  E-value: 1.24e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   37 LKGRDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDI 116
Cdd:PRK04284   4 LRNRSFLTLLDFTPKEIEYLLDLSEDLK-RAKYAGIEVQKLKGKNIALIFEKDSTRTRCAFEVAAYDQGAHVTYLGPTGS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  117 HLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHY-SSLKGLTLSWIG 195
Cdd:PRK04284  83 QMGKKESTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEHLkKPYKDIKFTYVG 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  196 DG-NNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEK 274
Cdd:PRK04284 163 DGrNNVANALMQGAAIMGMDFHLVCPKELNPDDELLNKCKEIAAETGGKITITDDIDEGVKGSDVIYTDVWVSMGEPDEV 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  275 -KKRLQAFQGYQVTMKTAKVAAS-DWTFLHCLPR------------------KPEEVDDEVFYSPRSLVFPEAENRKWTI 334
Cdd:PRK04284 243 wEERIKLLKPYQVNKEMMKKTGNpNAIFEHCLPSfhdldtkvgkeifekyglKEMEVTDEVFESKASVVFDEAENRMHTI 322

                        330
                 ....*....|
gi 38788445  335 MAVMVSLLTD 344
Cdd:PRK04284 323 KAVMVATLGE 332
PRK03515 PRK03515
ornithine carbamoyltransferase subunit I; Provisional
 36-342 9.21e-81

ornithine carbamoyltransferase subunit I; Provisional


Pssm-ID: 179587 [Multi-domain]  Cd Length: 336  Bit Score: 249.63  E-value: 9.21e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   36 QLKGRDLLTLKNFTGEEIKYMLWLSADLKFRiKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQD 115
Cdd:PRK03515   3 QFYQRHFLRLLDFTPAELNSLLQLAAKLKAD-KKNGKEEQKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  116 IHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHY--SSLKGLTLSW 193
Cdd:PRK03515  82 SQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpgKAFNEMTLAY 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  194 IGDG-NNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEE 272
Cdd:PRK03515 162 AGDArNNMGNSLLEAAALTGLDLRLVAPKACWPEAALVTECRALAQKNGGNITLTEDIAEGVKGADFIYTDVWVSMGEPK 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  273 EK-KKRLQAFQGYQVTMKTAKVAA-SDWTFLHCLPRKPE-------------------EVDDEVFYSPRSLVFPEAENRK 331
Cdd:PRK03515 242 EVwAERIALLRPYQVNSKMMQLTGnPQVKFLHCLPAFHDdqttlgkkmaeeyglhggmEVTDEVFESAHSIVFDQAENRL 321

                        330
                 ....*....|.
gi 38788445  332 WTIMAVMVSLL 342
Cdd:PRK03515 322 HTIKAVMVATL 332
PRK01713 PRK01713
ornithine carbamoyltransferase; Provisional
 37-342 1.34e-75

ornithine carbamoyltransferase; Provisional


Pssm-ID: 167263 [Multi-domain]  Cd Length: 334  Bit Score: 236.42  E-value: 1.34e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   37 LKGRDLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDI 116
Cdd:PRK01713   5 LKNRHLLSLVNHTEREIKYLLDLSRDLK-RAKYAGTEQQRLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTYIDPNSS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  117 HLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSS-LKGLTLSWIG 195
Cdd:PRK01713  84 QIGHKESMKDTARVLGRMYDAIEYRGFKQSIVNELAEYAGVPVFNGLTDEFHPTQMLADVLTMIENCDKpLSEISYVYIG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  196 DG-NNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEK 274
Cdd:PRK01713 164 DArNNMGNSLLLIGAKLGMDVRICAPKALLPEASLVEMCEKFAKESGARITVTDDIDKAVKGVDFVHTDVWVSMGEPLET 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  275 -KKRLQAFQGYQVTMKTAKVAAS-DWTFLHCLP---------------RKPE-----EVDDEVFYSPRSLVFPEAENRKW 332
Cdd:PRK01713 244 wGERIKLLMPYQVTPELMKRTGNpKVKFMHCLPafhnsetkvgrqiaeKYPElangiEVTEDVFESPMNIAFEQAENRMH 323

                        330
                 ....*....|
gi 38788445  333 TIMAVMVSLL 342
Cdd:PRK01713 324 TIKAVMVASL 333
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
41-181 3.71e-66

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 205.35  E-value: 3.71e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445    41 DLLTLKNFTGEEIKYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGV 120
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELK-EARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSS 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 38788445   121 NESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQE 181
Cdd:pfam02729  80 GESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
PRK12562 PRK12562
ornithine carbamoyltransferase subunit F; Provisional
 40-342 5.91e-66

ornithine carbamoyltransferase subunit F; Provisional


Pssm-ID: 105755  Cd Length: 334  Bit Score: 211.46  E-value: 5.91e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   40 RDLLTLKNFTGEEIKYMLWLSADLKFRiKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLG 119
Cdd:PRK12562   7 KHFLKLLDFTPAELNSLLQLAAKLKAD-KKNGKEVARLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  120 VNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHY--SSLKGLTLSWIGDG 197
Cdd:PRK12562  86 HKESIKDTARVLGRMYDGIQYRGHGQEVVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpgKAFNEMTLVYAGDA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  198 -NNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEK-K 275
Cdd:PRK12562 166 rNNMGNSMLEAAALTGLDLRLVAPQACWPEASLVAECSALAQKHGGKITLTEDIAAGVKGADFIYTDVWVSMGEPKEKwA 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  276 KRLQAFQGYQVTMK-TAKVAASDWTFLHCLPRKPE-------------------EVDDEVFYSPRSLVFPEAENRKWTIM 335
Cdd:PRK12562 246 ERIALLRGYQVNSKmMALTGNPQVKFLHCLPAFHDdqttlgkkmakefglhggmEVTDEVFESPASIVFDQAENRMHTIK 325


                 ....*..
gi 38788445  336 AVMVSLL 342
Cdd:PRK12562 326 AVMVATL 332
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
190-341 2.03e-64

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 201.30  E-value: 2.03e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   190 TLSWIGDG-NNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISM 268
Cdd:pfam00185   1 KIAYVGDGhNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAEAVKGADVVYTDVWQSM 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 38788445   269 GQEEEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRK-PEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSL 341
Cdd:pfam00185  81 GQEKEREERLKAFKPYQVNEELMKLAKKDAIFMHCLPAHrGEEVTDDVFDGPRSVVFDQAENRLHAQKALLALL 154
PRK04523 PRK04523
N-acetylornithine carbamoyltransferase; Reviewed
 40-341 2.57e-43

N-acetylornithine carbamoyltransferase; Reviewed


Pssm-ID: 235304 [Multi-domain]  Cd Length: 335  Bit Score: 152.59  E-value: 2.57e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   40 RDLLTLKNFTGEEIKYMLWLSADLKfrikqKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQ----- 114
Cdd:PRK04523   4 KHFLNTQDWSRAELDALLTQAAAFK-----RNKLGSALKGKSIALVFFNPSLRTRTSFELGAFQLGGHAVVLQPGkdawp 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  115 -DIHLGV------NESLTDTARVLSSMADAVLARVY-KQSD---------LDTLAKEASIPIINgLSDLYHPIQILADYL 177
Cdd:PRK04523  79 iEFELGAvmdgetEEHIREVARVLSRYVDLIGVRAFpKFVDwskdrqdqvLNSFAKYSTVPVIN-METITHPCQELAHAL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  178 TLQEHYSSL---KGLTLSWIGD----GNNILHSIMMSAAKFGMHLQAATPK-GYEPDASVTKLAEQYAKENGTKLLLTND 249
Cdd:PRK04523 158 ALQEHFGTTlrgKKYVLTWTYHpkplNTAVANSALLIATRLGMDVTLLCPTpDYILDERYMDWAEQNAAESGGSLTVSHD 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  250 PLEAAHGGNVLITDTW---ISMGQEEEKKKRLQAFQGYQVTMKtaKVAAS-DWTFLHCLP-RKPEEVDDEVFYSPRSLVF 324
Cdd:PRK04523 238 IDSAYAGADVVYAKSWgalPFFGNWEPEKPIRDQYQHFIVDER--KMALTnNGVFSHCLPlRRNVKVTDAVMDSPNCIAI 315

                        330
                 ....*....|....*..
gi 38788445  325 PEAENRKWTIMAVMVSL 341
Cdd:PRK04523 316 DEAENRLHVQKAIMAAL 332
PRK14804 PRK14804
ornithine carbamoyltransferase; Provisional
 40-342 4.83e-42

ornithine carbamoyltransferase; Provisional


Pssm-ID: 173265 [Multi-domain]  Cd Length: 311  Bit Score: 148.64  E-value: 4.83e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   40 RDLLTLKNFTGEEIKYMLWLSADLKfriKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTtqdiHLG 119
Cdd:PRK14804   7 KHLISWEDWSDSEILDLLDFAVHVK---KNRVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLD----WMA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  120 VNESLTDT---ARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLT--LQEHYSSLKGLTLSWI 194
Cdd:PRK14804  80 SNFQLSDIdleARYLSRNVSVIMARLKKHEDLLVMKNGSQVPVINGCDNMFHPCQSLADIMTiaLDSPEIPLNQKQLTYI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  195 GDGNNILHSIMMSAAKFGMHLQAATPkgYEPDASVTKLAEQYAKENGTkLLLTNDPLEAAHGGNVLITDTWISM------ 268
Cdd:PRK14804 160 GVHNNVVNSLIGITAALGIHLTLVTP--IAAKENIHAQTVERAKKKGT-LSWEMNLHKAVSHADYVYTDTWLDMeffndp 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 38788445  269 GQEEEKKKRLQAFQGYQVTMKTAKvaASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PRK14804 237 SYADKKKQRMELMMPYQINSSLME--KTNAKVMHDMPiHAGYEITREVVLSDRSIIFQQAENRLDAQKAVILKLL 309
pyrB PRK00856
aspartate carbamoyltransferase catalytic subunit;
36-344 4.80e-26

aspartate carbamoyltransferase catalytic subunit;


Pssm-ID: 234849 [Multi-domain]  Cd Length: 305  Bit Score: 105.54  E-value: 4.80e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   36 QLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHpcfltTQD 115
Cdd:PRK00856   2 PLKMKHLLSIEDLSREEIELLLDTAEEFKEVLRREVKKVPLLRGKTVANLFFEPSTRTRLSFELAAKRLGAD-----VIN 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  116 IHLGVN-----ESLTDTARVLSSM-ADAVLARvYKQSDL-DTLAKEASIPIIN---GLSDlyHPIQILADYLTLQEHYSS 185
Cdd:PRK00856  77 FSASTSsvskgETLADTIRTLSAMgADAIVIR-HPQSGAaRLLAESSDVPVINagdGSHQ--HPTQALLDLLTIREEFGR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  186 LKGLTLSWIGDgnnILH-----SIMMSAAKFGMHLQAATPKGYEPDAsvtklAEQYAkengtkllLTNDPLEAAHGGNVL 260
Cdd:PRK00856 154 LEGLKVAIVGD---IKHsrvarSNIQALTRLGAEVRLIAPPTLLPEG-----MPEYG--------VHTDLDEVIEDADVV 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  261 I---------TDTWISmgqEEEKKKRLqafqgYQVTMKTAKVAASDWTFLHCLPRKPE-EVDDEVFYSPRSLVFPEAEN- 329
Cdd:PRK00856 218 MmlrvqkermDGGLLP---SYEEYKRS-----YGLTAERLALAKPDAIVMHPGPVNRGvEIASDVADGPQSVIFEQVTNg 289

                        330
                 ....*....|....*...
gi 38788445  330 ---RkwtiMAVMVSLLTD 344
Cdd:PRK00856 290 vavR----MAVLELLLGG 303
PLN02527 PLN02527
aspartate carbamoyltransferase
 41-345 4.15e-21

aspartate carbamoyltransferase


Pssm-ID: 178142 [Multi-domain]  Cd Length: 306  Bit Score: 92.12  E-value: 4.15e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   41 DLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYlPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHpcFLTTQDI---- 116
Cdd:PLN02527   2 DVIEAQQFDREMLELLFEVAREMEKVERGSPGS-QMLKGYLMATLFYEPSTRTRLSFESAMKRLGGE--VLTTENAgefs 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  117 HLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIIN-GLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIG 195
Cdd:PLN02527  79 SAAKGETLEDTIRTVEGYSDIIVLRHFESGAARRAAATAEIPVINaGDGPGQHPTQALLDVYTIQREIGRLDGIKVGLVG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  196 DGNN--ILHSIMMSAAKF-GMHLQAATPKGYEPDASVtklaEQYAKENGTKLLLTNDPLEAAHGGNVLITdTWIsmgQEE 272
Cdd:PLN02527 159 DLANgrTVRSLAYLLAKYeDVKIYFVAPDVVKMKDDI----KDYLTSKGVEWEESSDLMEVASKCDVLYQ-TRI---QRE 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  273 EKKKRLQAFQG----YQVTMKTAKVAASDWTFLHCLPRKPE---EVDDEvfysPRSLVFPEAENRKWTIMAVMVSLLTDY 345
Cdd:PLN02527 231 RFGERIDLYEAargkYIVDKKVMDVLPKHAVVMHPLPRLDEittDVDSD----PRAAYFRQAKNGLFIRMALLKLLLGGW 306
PRK11891 PRK11891
aspartate carbamoyltransferase; Provisional
 29-342 4.60e-18

aspartate carbamoyltransferase; Provisional


Pssm-ID: 183362 [Multi-domain]  Cd Length: 429  Bit Score: 84.92  E-value: 4.60e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   29 QPLQNKVQLKGR-DLLTLKNFTGEEIKyMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGH 107
Cdd:PRK11891  76 QPLADQFAFEGKpQLLSVDQFSRDSVE-ALFRVADVMQPIARRQKISRVLEGAVLGNLFFEASTRTRVSFGAAFCRLGGS 154

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  108 PCflTTQDI---HLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIIN-GLSDLYHPIQILADYLTLQEHY 183
Cdd:PRK11891 155 VC--DTTGFtfsSMAKGESIYDTSRVMSGYVDALVIRHPEQGSVAEFARATNLPVINgGDGPGEHPSQALLDLYTIQREF 232

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  184 SSL----KGLTLSWIGD---GNNIlHSIMMSAAKF-GMHLQAATPKGYEPDASVTklaEQYAKeNGTKLLLTNDPLEAAH 255
Cdd:PRK11891 233 SRLgkivDGAHIALVGDlkyGRTV-HSLVKLLALYrGLKFTLVSPPTLEMPAYIV---EQISR-NGHVIEQTDDLAAGLR 307

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  256 GGNVlITDTWIsmgqeeeKKKRL--QAFQGY----QVTMKTA-KVAASDWTFLHCLPR--KPEEVD--DEVFYSPRSLVF 324
Cdd:PRK11891 308 GADV-VYATRI-------QKERFadESFEGYtpdfQINQALVdAVCKPDTLIMHPLPRdsRPGANDlsTDLNRDPRLAIF 379

                        330
                 ....*....|....*...
gi 38788445  325 PEAENRKWTIMAVMVSLL 342
Cdd:PRK11891 380 RQTDNGIPVRMAIFAVLL 397
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
 85-339 2.93e-17

aspartate/ornithine carbamoyltransferase family protein; Validated


Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 82.09  E-value: 2.93e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   85 IFEKRSTRTRLSTETGFALLGghpcfLTTQDIHLGVN-----ESLTDTARVLSSMADAVLAR---------VYKQ---SD 147
Cdd:PRK07200  65 VFRDNSTRTRFSYASACNLLG-----LEVQDLDEGKSqiahgETVRETANMISFMADVIGIRddmyigkgnAYMRevgAA 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  148 LDTLAKEASIP----IINGLSDLYHPIQILADYLTLQEHYSSL-----KGLTLSWI-----GDGNNILHSIMMSAAKFGM 213
Cdd:PRK07200 140 VDDGYKQGVLPqrptLVNLQCDIDHPTQSMADLLHLIEHFGGLenlkgKKIAMTWAyspsyGKPLSVPQGIIGLMTRFGM 219

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  214 HLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEK---------------KKRL 278
Cdd:PRK07200 220 DVTLAHPEGYDLMPEVVEVAKKNAKASGGSFRQVNSMEEAFKDADIVYPKSWAPYKVMEERtelyragdhegikalEKEL 299

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 38788445  279 QA----FQGYQVT---MKTAKvaASDWTFLHCLPR-------KPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMV 339
Cdd:PRK07200 300 LAqnaqHKDWHCTeemMKLTK--DGKALYMHCLPAdisgvscKEGEVTESVFDRYRIALYKEASWKPYIIAAMIF 372
PRK08192 PRK08192
aspartate carbamoyltransferase; Provisional
 36-212 5.14e-16

aspartate carbamoyltransferase; Provisional


Pssm-ID: 169269 [Multi-domain]  Cd Length: 338  Bit Score: 77.84  E-value: 5.14e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   36 QLKGRDLLTLKNFTGEEIKYMLWLSADLK-FRIKQKgeYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLT-T 113
Cdd:PRK08192   2 QFQGSHILSVNQLDRDAIQRIFNVADRMEpYALREK--RTRVLEGAILGNLFFEPSTRTRVSFGCAFNLLGGHVRETTgM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  114 QDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGlSD--LYHPIQILADYLTLQEHysslkgltL 191
Cdd:PRK08192  80 ASSSLSKGESLYDTARVLSTYSDVIAMRHPDAGSVKEFAEGSRVPVING-GDgsNEHPTQALLDLFTIQKE--------L 150

                        170       180
                 ....*....|....*....|.
gi 38788445  192 SWIGDGNNILHSIMMSAAKFG 212
Cdd:PRK08192 151 AHAGRGIDGMHIAMVGDLKFG 171
pyrB PRK13814
aspartate carbamoyltransferase;
42-345 4.63e-07

aspartate carbamoyltransferase;


Pssm-ID: 139876 [Multi-domain]  Cd Length: 310  Bit Score: 50.87  E-value: 4.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445   42 LLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGVN 121
Cdd:PRK13814   8 LLNMRSLTRDHIEKLIQRANYFLTQGMEKNSVFETLKGHVVANLFFEPSTRTRNSFEIAAKRLGAMVLNPNLKISAISKG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  122 ESLTDTARVLSSMAdaVLARVYKQSDLDT---LAKEAS--IPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGD 196
Cdd:PRK13814  88 ETLFDTIKTLEAMG--VYFFIVRHSENETpeqIAKQLSsgVVINAGDGNHQHPSQALIDLMTIKQHKPHWNKLCVTIIGD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  197 --GNNILHSIMMSAAKFGM-HLQAATPKGYEPDA----SVTKLAEQYAkengtkllltndpleaahggNVLITDTWISMG 269
Cdd:PRK13814 166 irHSRVANSLMDGLVTMGVpEIRLVGPSSLLPDKvgndSIKKFTELKP--------------------SLLNSDVIVTLR 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38788445  270 QEEEKKKR---LQAFQG-YQVTMKTAKVAASDWTFLHCLPRKPE-EVDDEVFYSPRSLVFPEAENRKWTIMAVM-VSLLT 343
Cdd:PRK13814 226 LQKERHDNsvdIDAFRGsFRLTPEKLYSAKPDAIVMHPGPVNREvEINSDVADNQQSVILQQVRNGVAMRMAVLeLFLLR 305


                 ..
gi 38788445  344 DY 345
Cdd:PRK13814 306 DF 307
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH