|
Name |
Accession |
Description |
Interval |
E-value |
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1031-1178 |
5.23e-69 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 228.92 E-value: 5.23e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1031 GTADAFIVRFVCNDDVYSGPLKFLHQDIdsgqGIRNTYFEFETALACV-PSPVDCQVTDLAGNEYDLTGLSTVRKPWTAV 1109
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1813753062 1110 DTSVDGRKRTFYLSVCNPLPYIPGCQgSAVGSCLVSEGNSWNLGVVQMSPQaAANGSLSIMYVNGDKCG 1178
Cdd:pfam00878 77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1322-1462 |
1.44e-63 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 213.13 E-value: 1.44e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1322 VYQRSTAIFFYCDRGT--QRPVFLKETS-DCSYLFEWRTQYACPPFDLTECSFKDGAGNSFDLSSLSRYSDNWEAITGTG 1398
Cdd:pfam00878 1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 1399 DP--EHYLINVCKslaPQAGTEPCPPEAAACLLGGSKPVNLGRVRDGPQWRDGIIVLKYVDGDLCP 1462
Cdd:pfam00878 81 DGkkRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
423-573 |
2.64e-61 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 206.58 E-value: 2.64e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 423 GFQRMSVINFECNKTAGNDgkgTPVFTGEV--DCTYFFTWDTEYACVKeKEDLLCGATDGK-KRYDLSALVRHAEpeqNW 499
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNG---APVFLHEDigDCSYFFEWETAYACVK-PEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1813753062 500 EAVDGSQTEtEKKHFFINICHrvlQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCG 573
Cdd:pfam00878 74 EAVDTSGDG-KKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
575-716 |
7.55e-47 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 165.36 E-value: 7.55e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 575 GKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVlsKTEGENCTVFDSqAGFSFDLSPLTKKNGAYKVET 654
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACV--KPEDVDCQVTDA-AGNEYDLSSLSRYSKNWEAVD 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1813753062 655 KKYD-----FYINVCGP-VSVSPCQPDSGACQVAKSdeKTWNLGLSNAKLSYYDGMIQLNYRGGTPYN 716
Cdd:pfam00878 78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDKG--KSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
723-875 |
1.22e-28 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 113.36 E-value: 1.22e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 723 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECVVTDPSTlEQYDLSSLAKSEGglggNWYAMDN 799
Cdd:pfam00878 4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 800 SGEHVTwRKYYINVCRPLNPVPGCNRYASACQMKYEKDQgsftevvsisNLGMAKTGPVVEDsGSLLLEYVNGSAC 875
Cdd:pfam00878 79 SGDGKK-RHFYINVCHPLPGIPGCPSAAGVCLVDKGKSW----------NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1466-1599 |
3.09e-20 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 89.09 E-value: 3.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1466 RKKSTTIRFTCSESQVNSRPMFISAV-EDCEYTFAWPTATACPMKSNEhdDCQVTNPStGHLFDLSSLSGRAG-----FT 1539
Cdd:pfam00878 2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweavDT 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1813753062 1540 AAYSEKGLVYMSICGEN---ENCPPGVGACF--GQTRISVGKANKRLRYVDQVLQLVYKDGSPCP 1599
Cdd:pfam00878 79 SGDGKKRHFYINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| FN2 |
cd00062 |
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
1897-1942 |
4.64e-18 |
|
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats.
:
Pssm-ID: 238019 Cd Length: 48 Bit Score: 79.66 E-value: 4.64e-18
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1813753062 1897 TDDGVPCVFPFIFNGKSYEECIIESRA--KLWCSTTADYDRDHEWGFC 1942
Cdd:cd00062 1 NSDGAPCVFPFIYRGKWYHDCTTEGSNdgKLWCSTTPNYDRDGKWGYC 48
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1759-1894 |
2.17e-16 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 78.31 E-value: 2.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1759 TSLIAFHCKRGVSMGTPKLLR--TSECDFVFEWETPVVCPDEVRMDgCTLTDEQLlYSFNLSSLSTS-------TFKVTR 1829
Cdd:pfam00878 5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYACVKPEDVD-CQVTDAAG-NEYDLSSLSRYsknweavDTSGDG 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 1830 DSRTYSVGVCTFAVGPEqgGCK-DGGVCLLSGTKGASFGRLQSMKLDYrhqDEAVVLSYVNGDRCP 1894
Cdd:pfam00878 83 KKRHFYINVCHPLPGIP--GCPsAAGVCLVDKGKSWNLGVVQSSPQKT---NGSIQLSYVNGDLCG 143
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1608-1731 |
4.60e-15 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 74.45 E-value: 4.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1608 SVISFVCRPEARPtNRPMLISLDKQTCTLFFSWHTPLAC--EQATECSVRNGSSI-VDLSPLIHRTGGYEAYDESEDDAS 1684
Cdd:pfam00878 6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACvkPEDVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1813753062 1685 DTnpdFYINICQPLNPMHGvpCPAGAAVCKVPIDGpPIDIGRVAGPP 1731
Cdd:pfam00878 85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
128-265 |
1.04e-12 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 67.52 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 128 SSIAFLCGKTL--GTPEFVTAT--ECVHYFEWRTTAACKKdifkaNKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDP 203
Cdd:pfam00878 6 TIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1813753062 204 DTS---LFINVCRdidtlrdPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVrKDRLVLSYV 265
Cdd:pfam00878 81 DGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKT-NGSIQLSYV 137
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1949-2083 |
3.52e-12 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 65.98 E-value: 3.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1949 RTSSIIFKCDEDEDIGRPQVFSEVRG-CDVTFEWKTKVVCPPKK-LECKFV-QKHKTYDLRLLSSLTGSWSLVHNGVS-- 2023
Cdd:pfam00878 4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVDTSGDgk 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 2024 ---YYINLCQKIYKGPlGCSERASICRRTTTGDVQvLGLVHTqKLGVIGDKVVVTYSKGYPCG 2083
Cdd:pfam00878 84 krhFYINVCHPLPGIP-GCPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
2241-2280 |
1.72e-05 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 46.72 E-value: 1.72e-05
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1813753062 2241 SSTIFFHCDPLVEDGIPEFSHET-ADCQYLFSWYTSAVCPL 2280
Cdd:pfam00878 5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVK 45
|
|
| ATG27 super family |
cl39051 |
Autophagy-related protein 27; |
1250-1365 |
1.80e-05 |
|
Autophagy-related protein 27;
The actual alignment was detected with superfamily member pfam02157:
Pssm-ID: 476860 Cd Length: 254 Bit Score: 48.62 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1250 VSAGEYTYYFRVCGKLSSdvcpTSDKSKVVsscQEKREPQGfHKVAGLLTQK----------LTYENGLlkmnfTGGDTC 1319
Cdd:pfam02157 43 SGPETYTYNFRVCREVGK----TASDAGLV---QIDKKNGK-ETVIGRINETqvfngsdwimLIYKGGD-----EYGSHC 109
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 1320 HKvYQRSTAIFFYCDRGTQRPVF-------LKETsDCSYLFEWRTQYACPPFD 1365
Cdd:pfam02157 110 GK-EKRKAIIMISCNRKVLADNFtivieerEKEQ-DCFYLFELDSSLACPPED 160
|
|
| CIMR super family |
cl39052 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
2089-2233 |
5.55e-04 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
The actual alignment was detected with superfamily member pfam00878:
Pssm-ID: 425923 Cd Length: 143 Bit Score: 42.48 E-value: 5.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 2089 SSVIELTCTKTV--GRPAFKRFDIDSCTYYFSWDSRAACaVKPqevQMVNGTITNPiNGKSFSLGdiyfKLFRASG---- 2162
Cdd:pfam00878 5 ATIIRFVCNDTAynGAPVFLHEDIGDCSYFFEWETAYAC-VKP---EDVDCQVTDA-AGNEYDLS----SLSRYSKnwea 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 2163 -DMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDqhfSRKVGTS-DKTKYYlqDGDLDVVFASSSKCG 2233
Cdd:pfam00878 76 vDTSGDGKKRHFYINVCHPLPGIPGCPSAAGVCLVDKGK---SWNLGVVqSSPQKT--NGSIQLSYVNGDLCG 143
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1031-1178 |
5.23e-69 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 228.92 E-value: 5.23e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1031 GTADAFIVRFVCNDDVYSGPLKFLHQDIdsgqGIRNTYFEFETALACV-PSPVDCQVTDLAGNEYDLTGLSTVRKPWTAV 1109
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1813753062 1110 DTSVDGRKRTFYLSVCNPLPYIPGCQgSAVGSCLVSEGNSWNLGVVQMSPQaAANGSLSIMYVNGDKCG 1178
Cdd:pfam00878 77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1322-1462 |
1.44e-63 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 213.13 E-value: 1.44e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1322 VYQRSTAIFFYCDRGT--QRPVFLKETS-DCSYLFEWRTQYACPPFDLTECSFKDGAGNSFDLSSLSRYSDNWEAITGTG 1398
Cdd:pfam00878 1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 1399 DP--EHYLINVCKslaPQAGTEPCPPEAAACLLGGSKPVNLGRVRDGPQWRDGIIVLKYVDGDLCP 1462
Cdd:pfam00878 81 DGkkRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
423-573 |
2.64e-61 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 206.58 E-value: 2.64e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 423 GFQRMSVINFECNKTAGNDgkgTPVFTGEV--DCTYFFTWDTEYACVKeKEDLLCGATDGK-KRYDLSALVRHAEpeqNW 499
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNG---APVFLHEDigDCSYFFEWETAYACVK-PEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1813753062 500 EAVDGSQTEtEKKHFFINICHrvlQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCG 573
Cdd:pfam00878 74 EAVDTSGDG-KKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
575-716 |
7.55e-47 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 165.36 E-value: 7.55e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 575 GKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVlsKTEGENCTVFDSqAGFSFDLSPLTKKNGAYKVET 654
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACV--KPEDVDCQVTDA-AGNEYDLSSLSRYSKNWEAVD 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1813753062 655 KKYD-----FYINVCGP-VSVSPCQPDSGACQVAKSdeKTWNLGLSNAKLSYYDGMIQLNYRGGTPYN 716
Cdd:pfam00878 78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDKG--KSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
723-875 |
1.22e-28 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 113.36 E-value: 1.22e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 723 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECVVTDPSTlEQYDLSSLAKSEGglggNWYAMDN 799
Cdd:pfam00878 4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 800 SGEHVTwRKYYINVCRPLNPVPGCNRYASACQMKYEKDQgsftevvsisNLGMAKTGPVVEDsGSLLLEYVNGSAC 875
Cdd:pfam00878 79 SGDGKK-RHFYINVCHPLPGIPGCPSAAGVCLVDKGKSW----------NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1466-1599 |
3.09e-20 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 89.09 E-value: 3.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1466 RKKSTTIRFTCSESQVNSRPMFISAV-EDCEYTFAWPTATACPMKSNEhdDCQVTNPStGHLFDLSSLSGRAG-----FT 1539
Cdd:pfam00878 2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweavDT 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1813753062 1540 AAYSEKGLVYMSICGEN---ENCPPGVGACF--GQTRISVGKANKRLRYVDQVLQLVYKDGSPCP 1599
Cdd:pfam00878 79 SGDGKKRHFYINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| FN2 |
cd00062 |
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
1897-1942 |
4.64e-18 |
|
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats.
Pssm-ID: 238019 Cd Length: 48 Bit Score: 79.66 E-value: 4.64e-18
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1813753062 1897 TDDGVPCVFPFIFNGKSYEECIIESRA--KLWCSTTADYDRDHEWGFC 1942
Cdd:cd00062 1 NSDGAPCVFPFIYRGKWYHDCTTEGSNdgKLWCSTTPNYDRDGKWGYC 48
|
|
| FN2 |
smart00059 |
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
1899-1942 |
7.40e-18 |
|
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function.
Pssm-ID: 128373 Cd Length: 49 Bit Score: 79.27 E-value: 7.40e-18
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1813753062 1899 DGVPCVFPFIFNGKSYEECIIESRA--KLWCSTTADYDRDHEWGFC 1942
Cdd:smart00059 4 DGEPCVFPFIYNGKKYHDCTSEGRSdgMLWCSTTPNYDRDGKWGFC 49
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1759-1894 |
2.17e-16 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 78.31 E-value: 2.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1759 TSLIAFHCKRGVSMGTPKLLR--TSECDFVFEWETPVVCPDEVRMDgCTLTDEQLlYSFNLSSLSTS-------TFKVTR 1829
Cdd:pfam00878 5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYACVKPEDVD-CQVTDAAG-NEYDLSSLSRYsknweavDTSGDG 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 1830 DSRTYSVGVCTFAVGPEqgGCK-DGGVCLLSGTKGASFGRLQSMKLDYrhqDEAVVLSYVNGDRCP 1894
Cdd:pfam00878 83 KKRHFYINVCHPLPGIP--GCPsAAGVCLVDKGKSWNLGVVQSSPQKT---NGSIQLSYVNGDLCG 143
|
|
| fn2 |
pfam00040 |
Fibronectin type II domain; |
1903-1942 |
3.35e-16 |
|
Fibronectin type II domain;
Pssm-ID: 459645 Cd Length: 42 Bit Score: 74.14 E-value: 3.35e-16
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1813753062 1903 CVFPFIFNGKSYEECIIESRA--KLWCSTTADYDRDHEWGFC 1942
Cdd:pfam00040 1 CVFPFKYKGKWYHTCTTDGRRsgRLWCATTANYDGDGKWGYC 42
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1608-1731 |
4.60e-15 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 74.45 E-value: 4.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1608 SVISFVCRPEARPtNRPMLISLDKQTCTLFFSWHTPLAC--EQATECSVRNGSSI-VDLSPLIHRTGGYEAYDESEDDAS 1684
Cdd:pfam00878 6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACvkPEDVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1813753062 1685 DTnpdFYINICQPLNPMHGvpCPAGAAVCKVPIDGpPIDIGRVAGPP 1731
Cdd:pfam00878 85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
128-265 |
1.04e-12 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 67.52 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 128 SSIAFLCGKTL--GTPEFVTAT--ECVHYFEWRTTAACKKdifkaNKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDP 203
Cdd:pfam00878 6 TIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1813753062 204 DTS---LFINVCRdidtlrdPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVrKDRLVLSYV 265
Cdd:pfam00878 81 DGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKT-NGSIQLSYV 137
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1949-2083 |
3.52e-12 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 65.98 E-value: 3.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1949 RTSSIIFKCDEDEDIGRPQVFSEVRG-CDVTFEWKTKVVCPPKK-LECKFV-QKHKTYDLRLLSSLTGSWSLVHNGVS-- 2023
Cdd:pfam00878 4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVDTSGDgk 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 2024 ---YYINLCQKIYKGPlGCSERASICRRTTTGDVQvLGLVHTqKLGVIGDKVVVTYSKGYPCG 2083
Cdd:pfam00878 84 krhFYINVCHPLPGIP-GCPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
2241-2280 |
1.72e-05 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 46.72 E-value: 1.72e-05
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1813753062 2241 SSTIFFHCDPLVEDGIPEFSHET-ADCQYLFSWYTSAVCPL 2280
Cdd:pfam00878 5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVK 45
|
|
| Man-6-P_recep |
pfam02157 |
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ... |
1250-1365 |
1.80e-05 |
|
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.
Pssm-ID: 460468 Cd Length: 254 Bit Score: 48.62 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1250 VSAGEYTYYFRVCGKLSSdvcpTSDKSKVVsscQEKREPQGfHKVAGLLTQK----------LTYENGLlkmnfTGGDTC 1319
Cdd:pfam02157 43 SGPETYTYNFRVCREVGK----TASDAGLV---QIDKKNGK-ETVIGRINETqvfngsdwimLIYKGGD-----EYGSHC 109
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 1320 HKvYQRSTAIFFYCDRGTQRPVF-------LKETsDCSYLFEWRTQYACPPFD 1365
Cdd:pfam02157 110 GK-EKRKAIIMISCNRKVLADNFtivieerEKEQ-DCFYLFELDSSLACPPED 160
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
2089-2233 |
5.55e-04 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 42.48 E-value: 5.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 2089 SSVIELTCTKTV--GRPAFKRFDIDSCTYYFSWDSRAACaVKPqevQMVNGTITNPiNGKSFSLGdiyfKLFRASG---- 2162
Cdd:pfam00878 5 ATIIRFVCNDTAynGAPVFLHEDIGDCSYFFEWETAYAC-VKP---EDVDCQVTDA-AGNEYDLS----SLSRYSKnwea 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 2163 -DMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDqhfSRKVGTS-DKTKYYlqDGDLDVVFASSSKCG 2233
Cdd:pfam00878 76 vDTSGDGKKRHFYINVCHPLPGIPGCPSAAGVCLVDKGK---SWNLGVVqSSPQKT--NGSIQLSYVNGDLCG 143
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1031-1178 |
5.23e-69 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 228.92 E-value: 5.23e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1031 GTADAFIVRFVCNDDVYSGPLKFLHQDIdsgqGIRNTYFEFETALACV-PSPVDCQVTDLAGNEYDLTGLSTVRKPWTAV 1109
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNGAPVFLHEDI----GDCSYFFEWETAYACVkPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAV 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1813753062 1110 DTSVDGRKRTFYLSVCNPLPYIPGCQgSAVGSCLVSEGNSWNLGVVQMSPQaAANGSLSIMYVNGDKCG 1178
Cdd:pfam00878 77 DTSGDGKKRHFYINVCHPLPGIPGCP-SAAGVCLVDKGKSWNLGVVQSSPQ-KTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1322-1462 |
1.44e-63 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 213.13 E-value: 1.44e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1322 VYQRSTAIFFYCDRGT--QRPVFLKETS-DCSYLFEWRTQYACPPFDLTECSFKDGAGNSFDLSSLSRYSDNWEAITGTG 1398
Cdd:pfam00878 1 GFQRATIIRFVCNDTAynGAPVFLHEDIgDCSYFFEWETAYACVKPEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 1399 DP--EHYLINVCKslaPQAGTEPCPPEAAACLLGGSKPVNLGRVRDGPQWRDGIIVLKYVDGDLCP 1462
Cdd:pfam00878 81 DGkkRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
423-573 |
2.64e-61 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 206.58 E-value: 2.64e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 423 GFQRMSVINFECNKTAGNDgkgTPVFTGEV--DCTYFFTWDTEYACVKeKEDLLCGATDGK-KRYDLSALVRHAEpeqNW 499
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNG---APVFLHEDigDCSYFFEWETAYACVK-PEDVDCQVTDAAgNEYDLSSLSRYSK---NW 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1813753062 500 EAVDGSQTEtEKKHFFINICHrvlQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCG 573
Cdd:pfam00878 74 EAVDTSGDG-KKRHFYINVCH---PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
575-716 |
7.55e-47 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 165.36 E-value: 7.55e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 575 GKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVlsKTEGENCTVFDSqAGFSFDLSPLTKKNGAYKVET 654
Cdd:pfam00878 1 GFQRATIIRFVCNDTAYNGAPVFLHEDIGDCSYFFEWETAYACV--KPEDVDCQVTDA-AGNEYDLSSLSRYSKNWEAVD 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1813753062 655 KKYD-----FYINVCGP-VSVSPCQPDSGACQVAKSdeKTWNLGLSNAKLSYYDGMIQLNYRGGTPYN 716
Cdd:pfam00878 78 TSGDgkkrhFYINVCHPlPGIPGCPSAAGVCLVDKG--KSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
723-875 |
1.22e-28 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 113.36 E-value: 1.22e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 723 RATLITFLCDRDAGVGFPEYQEEDNS--TYNFRWYTSYACPE-EPLECVVTDPSTlEQYDLSSLAKSEGglggNWYAMDN 799
Cdd:pfam00878 4 RATIIRFVCNDTAYNGAPVFLHEDIGdcSYFFEWETAYACVKpEDVDCQVTDAAG-NEYDLSSLSRYSK----NWEAVDT 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 800 SGEHVTwRKYYINVCRPLNPVPGCNRYASACQMKYEKDQgsftevvsisNLGMAKTGPVVEDsGSLLLEYVNGSAC 875
Cdd:pfam00878 79 SGDGKK-RHFYINVCHPLPGIPGCPSAAGVCLVDKGKSW----------NLGVVQSSPQKTN-GSIQLSYVNGDLC 142
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1466-1599 |
3.09e-20 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 89.09 E-value: 3.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1466 RKKSTTIRFTCSESQVNSRPMFISAV-EDCEYTFAWPTATACPMKSNEhdDCQVTNPStGHLFDLSSLSGRAG-----FT 1539
Cdd:pfam00878 2 FQRATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVKPEDV--DCQVTDAA-GNEYDLSSLSRYSKnweavDT 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1813753062 1540 AAYSEKGLVYMSICGEN---ENCPPGVGACF--GQTRISVGKANKRLRYVDQVLQLVYKDGSPCP 1599
Cdd:pfam00878 79 SGDGKKRHFYINVCHPLpgiPGCPSAAGVCLvdKGKSWNLGVVQSSPQKTNGSIQLSYVNGDLCG 143
|
|
| FN2 |
cd00062 |
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
1897-1942 |
4.64e-18 |
|
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats.
Pssm-ID: 238019 Cd Length: 48 Bit Score: 79.66 E-value: 4.64e-18
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1813753062 1897 TDDGVPCVFPFIFNGKSYEECIIESRA--KLWCSTTADYDRDHEWGFC 1942
Cdd:cd00062 1 NSDGAPCVFPFIYRGKWYHDCTTEGSNdgKLWCSTTPNYDRDGKWGYC 48
|
|
| FN2 |
smart00059 |
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
1899-1942 |
7.40e-18 |
|
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function.
Pssm-ID: 128373 Cd Length: 49 Bit Score: 79.27 E-value: 7.40e-18
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1813753062 1899 DGVPCVFPFIFNGKSYEECIIESRA--KLWCSTTADYDRDHEWGFC 1942
Cdd:smart00059 4 DGEPCVFPFIYNGKKYHDCTSEGRSdgMLWCSTTPNYDRDGKWGFC 49
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1759-1894 |
2.17e-16 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 78.31 E-value: 2.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1759 TSLIAFHCKRGVSMGTPKLLR--TSECDFVFEWETPVVCPDEVRMDgCTLTDEQLlYSFNLSSLSTS-------TFKVTR 1829
Cdd:pfam00878 5 ATIIRFVCNDTAYNGAPVFLHedIGDCSYFFEWETAYACVKPEDVD-CQVTDAAG-NEYDLSSLSRYsknweavDTSGDG 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1813753062 1830 DSRTYSVGVCTFAVGPEqgGCK-DGGVCLLSGTKGASFGRLQSMKLDYrhqDEAVVLSYVNGDRCP 1894
Cdd:pfam00878 83 KKRHFYINVCHPLPGIP--GCPsAAGVCLVDKGKSWNLGVVQSSPQKT---NGSIQLSYVNGDLCG 143
|
|
| fn2 |
pfam00040 |
Fibronectin type II domain; |
1903-1942 |
3.35e-16 |
|
Fibronectin type II domain;
Pssm-ID: 459645 Cd Length: 42 Bit Score: 74.14 E-value: 3.35e-16
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1813753062 1903 CVFPFIFNGKSYEECIIESRA--KLWCSTTADYDRDHEWGFC 1942
Cdd:pfam00040 1 CVFPFKYKGKWYHTCTTDGRRsgRLWCATTANYDGDGKWGYC 42
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1608-1731 |
4.60e-15 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 74.45 E-value: 4.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1608 SVISFVCRPEARPtNRPMLISLDKQTCTLFFSWHTPLAC--EQATECSVRNGSSI-VDLSPLIHRTGGYEAYDESEDDAS 1684
Cdd:pfam00878 6 TIIRFVCNDTAYN-GAPVFLHEDIGDCSYFFEWETAYACvkPEDVDCQVTDAAGNeYDLSSLSRYSKNWEAVDTSGDGKK 84
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1813753062 1685 DTnpdFYINICQPLNPMHGvpCPAGAAVCKVPIDGpPIDIGRVAGPP 1731
Cdd:pfam00878 85 RH---FYINVCHPLPGIPG--CPSAAGVCLVDKGK-SWNLGVVQSSP 125
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
128-265 |
1.04e-12 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 67.52 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 128 SSIAFLCGKTL--GTPEFVTAT--ECVHYFEWRTTAACKKdifkaNKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDP 203
Cdd:pfam00878 6 TIIRFVCNDTAynGAPVFLHEDigDCSYFFEWETAYACVK-----PEDVDCQVTDAAGNEYDLSSLSRYSKNWEAVDTSG 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1813753062 204 DTS---LFINVCRdidtlrdPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVrKDRLVLSYV 265
Cdd:pfam00878 81 DGKkrhFYINVCH-------PLPGIPGCPSAAGVCLVDKGKSWNLGVVQSSPQKT-NGSIQLSYV 137
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
1949-2083 |
3.52e-12 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 65.98 E-value: 3.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1949 RTSSIIFKCDEDEDIGRPQVFSEVRG-CDVTFEWKTKVVCPPKK-LECKFV-QKHKTYDLRLLSSLTGSWSLVHNGVS-- 2023
Cdd:pfam00878 4 RATIIRFVCNDTAYNGAPVFLHEDIGdCSYFFEWETAYACVKPEdVDCQVTdAAGNEYDLSSLSRYSKNWEAVDTSGDgk 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 2024 ---YYINLCQKIYKGPlGCSERASICRRTTTGDVQvLGLVHTqKLGVIGDKVVVTYSKGYPCG 2083
Cdd:pfam00878 84 krhFYINVCHPLPGIP-GCPSAAGVCLVDKGKSWN-LGVVQS-SPQKTNGSIQLSYVNGDLCG 143
|
|
| ATG27 |
pfam09451 |
Autophagy-related protein 27; |
1634-1715 |
1.45e-06 |
|
Autophagy-related protein 27;
Pssm-ID: 430622 Cd Length: 261 Bit Score: 52.34 E-value: 1.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1634 CTLFFSWHTPLACEQATECSVRNGSSIVDLSPLihrTGGYEAYDESEDDASDTNPDFYINICQPLNPMHGVP----CPAG 1709
Cdd:pfam09451 1 LLLLLPLLAAASAVSAFDCSVDKGLKKYDLSKL---KGPHSVSTTRDTPPSTTNTTWTINICEPLKKDKDVDkpdqCPKG 77
|
....*.
gi 1813753062 1710 AAVCKV 1715
Cdd:pfam09451 78 TRVCGI 83
|
|
| ATG27 |
pfam09451 |
Autophagy-related protein 27; |
475-617 |
2.45e-06 |
|
Autophagy-related protein 27;
Pssm-ID: 430622 Cd Length: 261 Bit Score: 51.57 E-value: 2.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 475 CGATDGKKRYDLSAL--------VRHAEPeqnweavdgSQTETEkkhFFINICHRVLQEG---KARGCPEDAAVCA---V 540
Cdd:pfam09451 19 CSVDKGLKKYDLSKLkgphsvstTRDTPP---------STTNTT---WTINICEPLKKDKdvdKPDQCPKGTRVCGitrV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 541 DKNGSKNLGKFIS-------------SPMKEKGNIQLSYSDGDdcGHGKKIKTNITLVCKPGDLESAPVLRTSGEGgcFY 607
Cdd:pfam09451 87 ILDGDDRITQVIPiggsnldpevtrlKTSDEKEGLRLTLKGGK--WGGNKQDAIIEFICDSDSLTFVSYDGSQEDD--KL 162
|
170
....*....|
gi 1813753062 608 EFEWHTAAAC 617
Cdd:pfam09451 163 RLEWKTKYAC 172
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
2241-2280 |
1.72e-05 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 46.72 E-value: 1.72e-05
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1813753062 2241 SSTIFFHCDPLVEDGIPEFSHET-ADCQYLFSWYTSAVCPL 2280
Cdd:pfam00878 5 ATIIRFVCNDTAYNGAPVFLHEDiGDCSYFFEWETAYACVK 45
|
|
| Man-6-P_recep |
pfam02157 |
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation ... |
1250-1365 |
1.80e-05 |
|
Mannose-6-phosphate receptor; This family includes both Cation-dependent and cation independent mannose-6-phosphate receptors.
Pssm-ID: 460468 Cd Length: 254 Bit Score: 48.62 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1250 VSAGEYTYYFRVCGKLSSdvcpTSDKSKVVsscQEKREPQGfHKVAGLLTQK----------LTYENGLlkmnfTGGDTC 1319
Cdd:pfam02157 43 SGPETYTYNFRVCREVGK----TASDAGLV---QIDKKNGK-ETVIGRINETqvfngsdwimLIYKGGD-----EYGSHC 109
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 1320 HKvYQRSTAIFFYCDRGTQRPVF-------LKETsDCSYLFEWRTQYACPPFD 1365
Cdd:pfam02157 110 GK-EKRKAIIMISCNRKVLADNFtivieerEKEQ-DCFYLFELDSSLACPPED 160
|
|
| ATG27 |
pfam09451 |
Autophagy-related protein 27; |
613-761 |
9.88e-05 |
|
Autophagy-related protein 27;
Pssm-ID: 430622 Cd Length: 261 Bit Score: 46.56 E-value: 9.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 613 TAAACVLSKTEGENCTVfdSQAGFSFDLSPLtkkNGAYKVETKKYD--------FYINVCGPVSVSP-------CQPDSG 677
Cdd:pfam09451 5 LPLLAAASAVSAFDCSV--DKGLKKYDLSKL---KGPHSVSTTRDTppsttnttWTINICEPLKKDKdvdkpdqCPKGTR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 678 ACQV-----AKSDEKTWNLGLSNAKLSY----------YDGmIQLNYRGGTpynnERHTPRATLITFLCDRDAgVGFPEY 742
Cdd:pfam09451 80 VCGItrvilDGDDRITQVIPIGGSNLDPevtrlktsdeKEG-LRLTLKGGK----WGGNKQDAIIEFICDSDS-LTFVSY 153
|
170 180
....*....|....*....|
gi 1813753062 743 Q-EEDNSTYNFRWYTSYACP 761
Cdd:pfam09451 154 DgSQEDDKLRLEWKTKYACE 173
|
|
| CIMR |
pfam00878 |
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent ... |
2089-2233 |
5.55e-04 |
|
Cation-independent mannose-6-phosphate receptor repeat; The cation-independent mannose-6-phosphate receptor contains 15 copies of a repeat.
Pssm-ID: 425923 Cd Length: 143 Bit Score: 42.48 E-value: 5.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 2089 SSVIELTCTKTV--GRPAFKRFDIDSCTYYFSWDSRAACaVKPqevQMVNGTITNPiNGKSFSLGdiyfKLFRASG---- 2162
Cdd:pfam00878 5 ATIIRFVCNDTAynGAPVFLHEDIGDCSYFFEWETAYAC-VKP---EDVDCQVTDA-AGNEYDLS----SLSRYSKnwea 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1813753062 2163 -DMRTNGDNYLYEIQLSSITSSRNPACSGANICQVKPNDqhfSRKVGTS-DKTKYYlqDGDLDVVFASSSKCG 2233
Cdd:pfam00878 76 vDTSGDGKKRHFYINVCHPLPGIPGCPSAAGVCLVDKGK---SWNLGVVqSSPQKT--NGSIQLSYVNGDLCG 143
|
|
| ATG27 |
pfam09451 |
Autophagy-related protein 27; |
1992-2126 |
1.12e-03 |
|
Autophagy-related protein 27;
Pssm-ID: 430622 Cd Length: 261 Bit Score: 43.48 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1992 LECKFVQKHKTYDlrlLSSLTGSWSLVH---------NgVSYYINLCQ-----KIYKGPLGCSERASICRRTTT------ 2051
Cdd:pfam09451 17 FDCSVDKGLKKYD---LSKLKGPHSVSTtrdtppsttN-TTWTINICEplkkdKDVDKPDQCPKGTRVCGITRVildgdd 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 2052 GDVQVLGLVHT------QKLGVIGDK--VVVTYSKGYpcGGNKTASSVIELTCTKTVGRpaFKRFDI--DSCTYYFSWDS 2121
Cdd:pfam09451 93 RITQVIPIGGSnldpevTRLKTSDEKegLRLTLKGGK--WGGNKQDAIIEFICDSDSLT--FVSYDGsqEDDKLRLEWKT 168
|
....*
gi 1813753062 2122 RAACA 2126
Cdd:pfam09451 169 KYACE 173
|
|
| ATG27 |
pfam09451 |
Autophagy-related protein 27; |
1226-1362 |
2.81e-03 |
|
Autophagy-related protein 27;
Pssm-ID: 430622 Cd Length: 261 Bit Score: 41.94 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1226 NCEVKDprHGNLYDLKPLG-------LNDTIVSAGEYTYYFRVCGKLSSDV-------CPTSDkskvvSSCQEKR----E 1287
Cdd:pfam09451 18 DCSVDK--GLKKYDLSKLKgphsvstTRDTPPSTTNTTWTINICEPLKKDKdvdkpdqCPKGT-----RVCGITRvildG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1813753062 1288 PQGFHKVAGLLTQKLTYE---------NGLLKMNFTGGDtcHKVYQRSTAIFFYCD-RGTQRPVFLKETSDCSYLFEWRT 1357
Cdd:pfam09451 91 DDRITQVIPIGGSNLDPEvtrlktsdeKEGLRLTLKGGK--WGGNKQDAIIEFICDsDSLTFVSYDGSQEDDKLRLEWKT 168
|
....*
gi 1813753062 1358 QYACP 1362
Cdd:pfam09451 169 KYACE 173
|
|
| |
