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Conserved domains on  [gi|156119611|ref|NP_001001343|]
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fibronectin type III domain-containing protein 9 [Homo sapiens]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 10637183)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain

CATH:  2.60.40.10
Gene Ontology:  GO:0005515
PubMed:  8981327|9837732|19576999

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 2-82 4.72e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


:

Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.68  E-value: 4.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156119611     2 NIEVGNISYTGAIISWSSSEPCLEDYYHIMYRPNWNSIFSGYlrysfhHEEKVPRTISSVVLEHLAPSTLYFLCISCKKA 81
Cdd:smart00060   6 NLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEW------KEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79


                   .
gi 156119611    82 A 82
Cdd:smart00060  80 A 80
 
Name Accession Description Interval E-value
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 2-82 4.72e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.68  E-value: 4.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156119611     2 NIEVGNISYTGAIISWSSSEPCLEDYYHIMYRPNWNSIFSGYlrysfhHEEKVPRTISSVVLEHLAPSTLYFLCISCKKA 81
Cdd:smart00060   6 NLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEW------KEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79


                   .
gi 156119611    82 A 82
Cdd:smart00060  80 A 80
fn3 pfam00041
Fibronectin type III domain;
2-76 1.42e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 39.32  E-value: 1.42e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 156119611    2 NIEVGNISYTGAIISWSSSEPCLE--DYYHIMYRPNWNSifsgylrySFHHEEKVPRTISSVVLEHLAPSTLYFLCI 76
Cdd:pfam00041   5 NLTVTDVTSTSLTVSWTPPPDGNGpiTGYEVEYRPKNSG--------EPWNEITVPGTTTSVTLTGLKPGTEYEVRV 73
 
Name Accession Description Interval E-value
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 2-82 4.72e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.68  E-value: 4.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156119611     2 NIEVGNISYTGAIISWSSSEPCLEDYYHIMYRPNWNSIFSGYlrysfhHEEKVPRTISSVVLEHLAPSTLYFLCISCKKA 81
Cdd:smart00060   6 NLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEW------KEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79


                   .
gi 156119611    82 A 82
Cdd:smart00060  80 A 80
fn3 pfam00041
Fibronectin type III domain;
2-76 1.42e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 39.32  E-value: 1.42e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 156119611    2 NIEVGNISYTGAIISWSSSEPCLE--DYYHIMYRPNWNSifsgylrySFHHEEKVPRTISSVVLEHLAPSTLYFLCI 76
Cdd:pfam00041   5 NLTVTDVTSTSLTVSWTPPPDGNGpiTGYEVEYRPKNSG--------EPWNEITVPGTTTSVTLTGLKPGTEYEVRV 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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