NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|237681328|ref|NP_001005305|]
View 

SLAIN motif-containing protein 1a [Danio rerio]

Protein Classification

SLAIN motif-containing protein( domain architecture ID 12172998)

SLAIN motif-containing protein is a microtubule plus-end tracking protein, similar to human SLAIN2 that binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 150-609 1.43e-136

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


:

Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 404.86  E-value: 1.43e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  150 WLYVSPKAKLFSHALLSPLQWCRHVLDNPKPEVELAKRSLCYKLDQAKRWRGVLSSCVSSSVlysPLDGVSSLSSCSKPF 229
Cdd:pfam15301   1 WLYVSPKKKVPSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQASRWRSLYSSPSSSSS---AYSGNAEASSYSSGL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  230 TKPALTEQTdppspnhqkpltgrnclsltersPTFLYHTATQSNSHRQRPLSPQSSIDSELSASELEEDSVSMSYKLQDM 309
Cdd:pfam15301  78 NSPGYLKST-----------------------NKQLLTCGSSGYLRRHSALSPQSSVDSELSTSELEDDSISMGYKLQDL 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  310 TDVEVMARLQEESLRQEYASTTATATRRSASFSIHTaARRSMRSEAELEEEEEYDQ----LSVPQPRLFRTASMQRstsh 385
Cdd:pfam15301 135 TDVQIMARLQEESLRQDYASTSASASRRSSSFSLHS-LRRGTYSDQELDAYSLEDEeeeyCSLPQPRLHRFSPLPH---- 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  386 tqnlSSMKDCRR--SPSTPQYLNSLSFQQLHVANNS--SPTAEAQSYRANTDKLRRSMPNLLRAPSIPsvinvpnvsapt 461
Cdd:pfam15301 210 ----SSPRDSPRsrSPSTSQEYSRLSAQRLRQPRRSlqGPGAELQKYAKSEEKLRRSMPNLARRTSLR------------ 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  462 ghiattsSLSLLRNSQSFDSH-----NALAKIQ---SAIPSPgqLQQRVQSVGNFSMAARPPLKATAYVSPTIQSSNTMA 533
Cdd:pfam15301 274 -------SLESVRNSRSFESNlqvpnSGLSRLQqssSSIPSP--SKLRVQSAGQSPLALRQPVKATSYVSSTVAGPSKGL 344

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 237681328  534 SSASLSCISSSSIPLPSKPSTPSSSRS--ALPRPASFV-GTNGASRSKIGQPVRSLLTPPKsvsALSALRDGSWRDGCY 609
Cdd:pfam15301 345 PSSQSLPSGGSSGSPLPSRPSGGYSGGrsSLPRPASFVgGTSPVPRSKLAQPVRRSLTPPK---TYSALRDESWKDGCY 420
 
Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 150-609 1.43e-136

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 404.86  E-value: 1.43e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  150 WLYVSPKAKLFSHALLSPLQWCRHVLDNPKPEVELAKRSLCYKLDQAKRWRGVLSSCVSSSVlysPLDGVSSLSSCSKPF 229
Cdd:pfam15301   1 WLYVSPKKKVPSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQASRWRSLYSSPSSSSS---AYSGNAEASSYSSGL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  230 TKPALTEQTdppspnhqkpltgrnclsltersPTFLYHTATQSNSHRQRPLSPQSSIDSELSASELEEDSVSMSYKLQDM 309
Cdd:pfam15301  78 NSPGYLKST-----------------------NKQLLTCGSSGYLRRHSALSPQSSVDSELSTSELEDDSISMGYKLQDL 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  310 TDVEVMARLQEESLRQEYASTTATATRRSASFSIHTaARRSMRSEAELEEEEEYDQ----LSVPQPRLFRTASMQRstsh 385
Cdd:pfam15301 135 TDVQIMARLQEESLRQDYASTSASASRRSSSFSLHS-LRRGTYSDQELDAYSLEDEeeeyCSLPQPRLHRFSPLPH---- 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  386 tqnlSSMKDCRR--SPSTPQYLNSLSFQQLHVANNS--SPTAEAQSYRANTDKLRRSMPNLLRAPSIPsvinvpnvsapt 461
Cdd:pfam15301 210 ----SSPRDSPRsrSPSTSQEYSRLSAQRLRQPRRSlqGPGAELQKYAKSEEKLRRSMPNLARRTSLR------------ 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  462 ghiattsSLSLLRNSQSFDSH-----NALAKIQ---SAIPSPgqLQQRVQSVGNFSMAARPPLKATAYVSPTIQSSNTMA 533
Cdd:pfam15301 274 -------SLESVRNSRSFESNlqvpnSGLSRLQqssSSIPSP--SKLRVQSAGQSPLALRQPVKATSYVSSTVAGPSKGL 344

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 237681328  534 SSASLSCISSSSIPLPSKPSTPSSSRS--ALPRPASFV-GTNGASRSKIGQPVRSLLTPPKsvsALSALRDGSWRDGCY 609
Cdd:pfam15301 345 PSSQSLPSGGSSGSPLPSRPSGGYSGGrsSLPRPASFVgGTSPVPRSKLAQPVRRSLTPPK---TYSALRDESWKDGCY 420
 
Name Accession Description Interval E-value
SLAIN pfam15301
SLAIN motif-containing family; The SLAIN motif containing family is named after the presence ...
 150-609 1.43e-136

SLAIN motif-containing family; The SLAIN motif containing family is named after the presence of a SLAIN motif in SLAIN1. They are a family of microtubule plus-end tracking proteins.


Pssm-ID: 464627 [Multi-domain]  Cd Length: 420  Bit Score: 404.86  E-value: 1.43e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  150 WLYVSPKAKLFSHALLSPLQWCRHVLDNPKPEVELAKRSLCYKLDQAKRWRGVLSSCVSSSVlysPLDGVSSLSSCSKPF 229
Cdd:pfam15301   1 WLYVSPKKKVPSQKPLSPLKWCRQVLDHPSPETEAAKRSLIHRLDQASRWRSLYSSPSSSSS---AYSGNAEASSYSSGL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  230 TKPALTEQTdppspnhqkpltgrnclsltersPTFLYHTATQSNSHRQRPLSPQSSIDSELSASELEEDSVSMSYKLQDM 309
Cdd:pfam15301  78 NSPGYLKST-----------------------NKQLLTCGSSGYLRRHSALSPQSSVDSELSTSELEDDSISMGYKLQDL 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  310 TDVEVMARLQEESLRQEYASTTATATRRSASFSIHTaARRSMRSEAELEEEEEYDQ----LSVPQPRLFRTASMQRstsh 385
Cdd:pfam15301 135 TDVQIMARLQEESLRQDYASTSASASRRSSSFSLHS-LRRGTYSDQELDAYSLEDEeeeyCSLPQPRLHRFSPLPH---- 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  386 tqnlSSMKDCRR--SPSTPQYLNSLSFQQLHVANNS--SPTAEAQSYRANTDKLRRSMPNLLRAPSIPsvinvpnvsapt 461
Cdd:pfam15301 210 ----SSPRDSPRsrSPSTSQEYSRLSAQRLRQPRRSlqGPGAELQKYAKSEEKLRRSMPNLARRTSLR------------ 273

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237681328  462 ghiattsSLSLLRNSQSFDSH-----NALAKIQ---SAIPSPgqLQQRVQSVGNFSMAARPPLKATAYVSPTIQSSNTMA 533
Cdd:pfam15301 274 -------SLESVRNSRSFESNlqvpnSGLSRLQqssSSIPSP--SKLRVQSAGQSPLALRQPVKATSYVSSTVAGPSKGL 344

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 237681328  534 SSASLSCISSSSIPLPSKPSTPSSSRS--ALPRPASFV-GTNGASRSKIGQPVRSLLTPPKsvsALSALRDGSWRDGCY 609
Cdd:pfam15301 345 PSSQSLPSGGSSGSPLPSRPSGGYSGGrsSLPRPASFVgGTSPVPRSKLAQPVRRSLTPPK---TYSALRDESWKDGCY 420
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH