NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|55749659|ref|NP_001006948|]
View 

bridge-like lipid transfer protein family member 3B isoform b [Homo sapiens]

Protein Classification

bridge-like lipid transfer protein( domain architecture ID 10576535)

bridge-like lipid transfer protein similar to Homo sapiens bridge-like lipid transfer protein family member 3A/3B, which acts as tube-forming lipid transport protein that mediates the transfer of lipids between membranes at organelle contact sites

Gene Ontology:  GO:0120009|GO:0120013|GO:0006869
PubMed:  35491307
TCDB:  1.R.2

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Chorein_N pfam12624
N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein ...
 1-96 1.61e-17

N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein sorting 13A (VPS13A) protein in vertebrates lead to the disease of chorea-acanthocytosis, the exact function of any of the regions within the protein is not yet known. This region is the proposed leucine zipper at the N-terminus. The full-length protein is a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport.


:

Pssm-ID: 463646  Cd Length: 116  Bit Score: 78.38  E-value: 1.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749659     1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLqNMLDLPtwLAINKVFCNKASIRIPWTKLKTHPI 80
Cdd:pfam12624   1 LESLVASLLNRYLGEYVENLDPDQLKVGLWSGDVVLENLKLKKEAL-DKLDLP--IEVKSGHIGKLTLKIPWTNLKSEPV 77

                          90
                  ....*....|....*.
gi 55749659    81 CLSLDKVIMEMSTCEE 96
Cdd:pfam12624  78 VIEIEDVYLLAVPKDE 93
 
Name Accession Description Interval E-value
Chorein_N pfam12624
N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein ...
 1-96 1.61e-17

N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein sorting 13A (VPS13A) protein in vertebrates lead to the disease of chorea-acanthocytosis, the exact function of any of the regions within the protein is not yet known. This region is the proposed leucine zipper at the N-terminus. The full-length protein is a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport.


Pssm-ID: 463646  Cd Length: 116  Bit Score: 78.38  E-value: 1.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749659     1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLqNMLDLPtwLAINKVFCNKASIRIPWTKLKTHPI 80
Cdd:pfam12624   1 LESLVASLLNRYLGEYVENLDPDQLKVGLWSGDVVLENLKLKKEAL-DKLDLP--IEVKSGHIGKLTLKIPWTNLKSEPV 77

                          90
                  ....*....|....*.
gi 55749659    81 CLSLDKVIMEMSTCEE 96
Cdd:pfam12624  78 VIEIEDVYLLAVPKDE 93
 
Name Accession Description Interval E-value
Chorein_N pfam12624
N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein ...
 1-96 1.61e-17

N-terminal region of Chorein or VPS13; Although mutations in the full-length vacuolar protein sorting 13A (VPS13A) protein in vertebrates lead to the disease of chorea-acanthocytosis, the exact function of any of the regions within the protein is not yet known. This region is the proposed leucine zipper at the N-terminus. The full-length protein is a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport.


Pssm-ID: 463646  Cd Length: 116  Bit Score: 78.38  E-value: 1.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749659     1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLqNMLDLPtwLAINKVFCNKASIRIPWTKLKTHPI 80
Cdd:pfam12624   1 LESLVASLLNRYLGEYVENLDPDQLKVGLWSGDVVLENLKLKKEAL-DKLDLP--IEVKSGHIGKLTLKIPWTNLKSEPV 77

                          90
                  ....*....|....*.
gi 55749659    81 CLSLDKVIMEMSTCEE 96
Cdd:pfam12624  78 VIEIEDVYLLAVPKDE 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH