|
Name |
Accession |
Description |
Interval |
E-value |
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
1-415 |
7.00e-131 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 381.79 E-value: 7.00e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 1 MSLkftnAKRIEGLDSNVWIEFTKL-----AADPSVVNLGQGFPDISPPTYVKEELskIAAI-DSLNQYTRGFGHPSLVK 74
Cdd:COG0436 1 MKL----SSRLARLPPSPIREVSALaaelkAAGEDVIDLGIGEPDFPTPDHIREAA--IEALdDGVTGYTPSAGIPELRE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 75 ALSYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPvygkrw 154
Cdd:COG0436 75 AIAAYYKRRYGVDLDPD-EILVTNGAKEALALALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEEN------ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 155 sssDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGM 234
Cdd:COG0436 148 ---GFLPDPEALEAAITPRTKAIVLNSPNNPTGAVYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLPGL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 235 WERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikrmDDPECYFNSLPKELEV 314
Cdd:COG0436 225 KDRTIVINSFSKSYAMTGWRIGYAVGPPELIAALLKLQSNLTSCAPTPAQYAAAAAL-------EGPQDYVEEMRAEYRR 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 315 KRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDlsdmknnepyDYKFVKWMTKHKKLSAIPVSAFCnsetkSQFEKFV 394
Cdd:COG0436 298 RRDLLVEGLNEIGLSVVKPEGAFYLFADVPELGLD----------SEEFAERLLEEAGVAVVPGSAFG-----PAGEGYV 362
|
410 420
....*....|....*....|.
gi 56713256 395 RFCFIKKDSTLDAAEEIIKAW 415
Cdd:COG0436 363 RISYATSEERLEEALERLARF 383
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
10-415 |
4.27e-117 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 346.64 E-value: 4.27e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 10 RIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQID 89
Cdd:PRK07777 5 RLRPFGTTIFAEMSALAVRTGAVNLGQGFPDEDGPPEMLEAAQE-AIAGGVNQYPPGPGIPELRAAIAAQRRRRYGLEYD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 90 SNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwSSSDWTLDPQELESK 169
Cdd:PRK07777 84 PDTEVLVTVGATEAIAAAVLGLVEPGDEVLLIEPYYDSYAAVIAMAGAHRVPVPLVP--------DGRGFALDLDALRAA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 170 FNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFS 249
Cdd:PRK07777 156 VTPRTRALIVNSPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPLATLPGMRERTVTISSAAKTFN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 250 VTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESVGLK 329
Cdd:PRK07777 236 VTGWKIGWACGPAPLIAAVRAAKQYLTYVGGAPFQPAVAHA-------LDHEDAWVAALRDSLQAKRDRLAAGLAEAGFE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 330 PIVPDGGYFIIADVSLLDPDLSdmknnepydYKFVKWMTKHKKLSAIPVSAFCNSEtkSQFEKFVRFCFIKKDSTLDAAE 409
Cdd:PRK07777 309 VHDSAGTYFLCADPRPLGYDDG---------TEFCRALPERVGVAAIPMSVFYDPA--DAWNHLVRFAFCKRDDTLDEAI 377
|
....*.
gi 56713256 410 EIIKAW 415
Cdd:PRK07777 378 RRLRAL 383
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
25-415 |
8.02e-117 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 346.19 E-value: 8.02e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 25 LAADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSL 104
Cdd:PRK08912 22 LAREHGAINLGQGFPDDPGPEDVRRAAAD-ALLDGSNQYPPMMGLPELRQAVAAHYARFQGLDLDPETEVMVTSGATEAL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 105 FNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLrsKPvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHN 184
Cdd:PRK08912 101 AAALLALVEPGDEVVLFQPLYDAYLPLIRRAGGVPRLVRL--EP--------PHWRLPRAALAAAFSPRTKAVLLNNPLN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 185 PLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHL 264
Cdd:PRK08912 171 PAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFDGRRHIPLMTLPGMRERTVKIGSAGKIFSLTGWKVGFVCAAPPL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 265 IKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESVGLkPIVPDGG-YFIIADV 343
Cdd:PRK08912 251 LRVLAKAHQFLTFTTPPNLQAAVAYG-------LGKPDDYFEGMRADLARSRDRLAAGLRRIGF-PVLPSQGtYFLTVDL 322
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56713256 344 SLLDPDLSDMknnepydyKFVKWMTKHKKLSAIPVSAFcnsetksqFEK-----FVRFCFIKKDSTLDAAEEIIKAW 415
Cdd:PRK08912 323 APLGLAEDDV--------AFCRRLVEEAGVAAIPVSAF--------YEEdpvtsVVRFCFAKRDATLDEAVERLAAA 383
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
8-413 |
8.20e-107 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 321.43 E-value: 8.20e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 8 AKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEelSKIAAI-DSLNQYTRGFGHPSLVKALSYLYEKLYQK 86
Cdd:PLN00175 33 AKRLEKFKTTIFTQMSSLAIKHGAINLGQGFPNFDGPDFVKE--AAIQAIrDGKNQYARGFGVPELNSAIAERFKKDTGL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 87 QIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwsssDWTLDPQEL 166
Cdd:PLN00175 111 VVDPEKEVTVTSGCTEAIAATILGLINPGDEVILFAPFYDSYEATLSMAGAKIKTVTLRPP----------DFAVPEDEL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 167 ESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNkHLKIATFPGMWERTITIGSAGK 246
Cdd:PLN00175 181 KAAFTSKTRAILINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAFEGD-HISMASLPGMYERTVTMNSLGK 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 247 TFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESV 326
Cdd:PLN00175 260 TFSLTGWKIGWAIAPPHLTWGVRQAHSFLTFATATPMQWAAVAA-------LRAPESYYEELKRDYSAKKDILVEGLKEV 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 327 GLKPIVPDGGYFIIADVSLLdpdlsDMKNnepyDYKFVKWMTKHKKLSAIPVSAF-CNSEtksQFEKFVRFCFIKKDSTL 405
Cdd:PLN00175 333 GFKVYPSSGTYFVMVDHTPF-----GFEN----DIAFCEYLIEEVGVAAIPPSVFyLNPE---DGKNLVRFAFCKDEETL 400
|
....*...
gi 56713256 406 DAAEEIIK 413
Cdd:PLN00175 401 RAAVERMK 408
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
22-410 |
3.36e-103 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 311.08 E-value: 3.36e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 22 FT---KLAADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTV 98
Cdd:PRK09082 20 FTvmsALAAEHGAINLSQGFPDFDGPPYLVEALAY-AMAAGHNQYPPMTGVAALREAIAAKTARLYGRQYDADSEITVTA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 99 GAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkPVYgkrwsSSDWtldpQELESKFNSKTKAII 178
Cdd:PRK09082 99 GATEALFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRVALQP-PDF-----RVDW----QRFAAAISPRTRLII 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 179 LNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWS 258
Cdd:PRK09082 169 LNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRHPELRERAFVVSSFGKTYHVTGWKVGYC 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 259 IGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikrMDDPECYfNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYF 338
Cdd:PRK09082 249 VAPAALSAEFRKVHQYNTFTVNTPAQLALADYL------RAEPEHY-LELPAFYQAKRDRFRAALANSRFKLLPCEGTYF 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56713256 339 IIADVSLLdPDLSDMknnepydyKFVKWMTKHKKLSAIPVSAFCNSetkSQFEKFVRFCFIKKDSTLDAAEE 410
Cdd:PRK09082 322 QLVDYSAI-SDLDDV--------EFCQWLTREHGVAAIPLSVFYAD---PFPHRLVRLCFAKQEETLDAAAE 381
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
32-414 |
2.09e-95 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 290.01 E-value: 2.09e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 32 VNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQAL 111
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYYPDPGLPELREAIAEWLGRRGGVDVPPE-EIVVTNGAQEALSLLLRAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 112 IDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYN 191
Cdd:cd00609 80 LNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEE---------GGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 192 REELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLkIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPN-HLIKHLQT 270
Cdd:cd00609 151 EEELEELAELAKKHGILIISDEAYAELVYDGEPPP-ALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPeELLERLKK 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 271 VQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESVG-LKPIVPDGGYFIIADVSlldpd 349
Cdd:cd00609 230 LLPYTTSGPSTLSQAAAAAA-------LDDGEEHLEELRERYRRRRDALLEALKELGpLVVVKPSGGFFLWLDLP----- 297
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56713256 350 lsdmknnEPYDYKFVKWMTKHKKLSAIPVSAFCnsetkSQFEKFVRFCFIKKDSTLDAAEEIIKA 414
Cdd:cd00609 298 -------EGDDEEFLERLLLEAGVVVRPGSAFG-----EGGEGFVRLSFATPEEELEEALERLAE 350
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
8-415 |
2.81e-88 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 273.15 E-value: 2.81e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 8 AKRIEGLDSNVWIEFTKLAA-------DpsVVNLGQGFPDISPPTYVKEelskiAAIDSLNQ----YTRGFGHPSLVKAL 76
Cdd:PRK05764 5 SKRVSRVTPSATLAVTAKAKelkaqgrD--VISLGAGEPDFDTPEHIKE-----AAIEALDDgktkYTPAAGIPELREAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 77 SYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsS 156
Cdd:PRK05764 78 AAKLKRDNGLDYDPS-QVIVTTGAKQALYNAFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPTGE---------E 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 157 SDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF-PGMW 235
Cdd:PRK05764 148 NGFKLTVEQLEAAITPKTKALILNSPSNPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTSIASLsPELR 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 236 ERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTiYTCATplqeALAQafWIDIKRMDDPECYFNSLPKELEVK 315
Cdd:PRK05764 228 DRTITVNGFSKAYAMTGWRLGYAAGPKELIKAMSKLQSHS-TSNPT----SIAQ--YAAVAALNGPQDEVEEMRQAFEER 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 316 RDRMVRLLESV-GLKPIVPDGGYFIIADVSlldpdlSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSEtksqfekFV 394
Cdd:PRK05764 301 RDLMVDGLNEIpGLECPKPEGAFYVFPNVS------KLLGKSITDSLEFAEALLEEAGVAVVPGIAFGAPG-------YV 367
|
410 420
....*....|....*....|.
gi 56713256 395 RFCFIKKDSTLDAAEEIIKAW 415
Cdd:PRK05764 368 RLSYATSLEDLEEGLERIERF 388
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
24-405 |
2.80e-71 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 229.29 E-value: 2.80e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 24 KLAADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGS 103
Cdd:PRK12414 24 QLAAQHDALNLSQGAPNFAPDPALVEGVAR-AMRDGHNQYAPMAGIAALREALAEKTERLYGARYDPASEVTVIASASEG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 104 LFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLrskpvygkrwSSSDWTLDPQELESKFNSKTKAIILNTPH 183
Cdd:PRK12414 103 LYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKL----------SPEDFRVNWDEVAAAITPRTRMIIVNTPH 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 184 NPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNH 263
Cdd:PRK12414 173 NPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMARHRELAERSVIVSSFGKSYHVTGWRVGYCLAPAE 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 264 LIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFnSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADV 343
Cdd:PRK12414 253 LMDEIRKVHQFMVFSADTPMQHAFAEA-------LAEPASYL-GLGAFYQRKRDLLARELAGSRFELLPSEGSFFMLARF 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56713256 344 SlldpDLSDMKNNEpydykFVKWMTKHKKLSAIPVSAFCNSETKSqfeKFVRFCFIKKDSTL 405
Cdd:PRK12414 325 R----HFSDESDSD-----FVLRLIRDARVATIPLSAFYTDGTDT---GLIRLSFSKDDATL 374
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
29-381 |
2.65e-60 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 200.72 E-value: 2.65e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 29 PSVVNLGQGFPDISPPTYVKEelSKIAAIDSlNQ--YTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFN 106
Cdd:PRK07309 30 PGILKLTLGEPDFTTPDHVKE--AAKRAIDA-NQshYTGMAGLLELRQAAADFVKEKYNLDYAPENEILVTIGATEALSA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 107 TIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwssSDWTLDPQELES---KFNSKTKAIILNTPH 183
Cdd:PRK07309 107 SLTAILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTE----------NDFVLTPEMLEKailEQGDKLKAVILNYPA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 184 NPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFpgMWERTITIGSAGKTFSVTGWKLGWSIGPNH 263
Cdd:PRK07309 177 NPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHVSIAEY--LPDQTILINGLSKSHAMTGWRIGLIFAPAE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 264 LIKHLQTVQQNTIYTCATPLQEALAQAFwidIKRMDDPEcyfnSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADV 343
Cdd:PRK07309 255 FTAQLIKSHQYLVTAATTMAQFAAVEAL---TNGKDDAL----PMKKEYIKRRDYIIEKMTDLGFKIIKPDGAFYIFAKI 327
|
330 340 350
....*....|....*....|....*....|....*...
gi 56713256 344 slldPDlsdmkNNEPYDYKFVKWMTKHKKLSAIPVSAF 381
Cdd:PRK07309 328 ----PA-----GYNQDSFKFLQDFARKKAVAFIPGAAF 356
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
21-398 |
1.29e-59 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 198.79 E-value: 1.29e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 21 EFTKLAAD-PSVVNLGQGFPDISPPTYVKEelSKIAAID-SLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTV 98
Cdd:PRK07683 19 QFSNMVQNyDNLISLTIGQPDFPTPSHVKE--AAKRAITeNYTSYTHNAGLLELRKAACNFVKDKYDLHYSPESEIIVTI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 99 GAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskpvygkrwsSSDWTLDPQELESKFNSKTKAII 178
Cdd:PRK07683 97 GASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTR----------STGFRLTAEALENAITEKTRCVV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 179 LNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGnKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWS 258
Cdd:PRK07683 167 LPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQ-PHTSIAHFPEMREKTIVINGLSKSHSMTGWRIGFL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 259 IGPNHLIKHLQTVQQNTIyTCATPLQ-----EALAQAFwidikrmDDPECYFNSLPKELEVKRDRMVrlleSVGLKPIVP 333
Cdd:PRK07683 246 FAPSYLAKHILKVHQYNV-TCASSISqyaalEALTAGK-------DDAKMMRHQYKKRRDYVYNRLI----SMGLDVEKP 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56713256 334 DGGYFIIadvslldPDLSDMKNNEpydYKFVKWMTKHKKLSAIPVSAFcnsetkSQF-EKFVRFCF 398
Cdd:PRK07683 314 TGAFYLF-------PSIGHFTMSS---FDFALDLVEEAGLAVVPGSAF------SEYgEGYVRLSY 363
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
1-381 |
1.69e-56 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 190.70 E-value: 1.69e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 1 MSLKFTnAKRIEGLDSNVWIEFTKLAAD-PSVVNLGQGFPDIspPTyvKEELSKIAAIDSLNQYTR---GFGHPSLVKAL 76
Cdd:PRK06348 1 MKNKFL-AKKYQQMEVNIMAEIATLAKKfPDIIDLSLGDPDL--IT--DESIINAAFEDAKKGHTRytdSGGDVELIEEI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 77 SYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwss 156
Cdd:PRK06348 76 IKYYSKNYDLSFKRN-EIMATVGACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYEE--------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 157 SDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSgNKHLKIATFPGMWE 236
Cdd:PRK06348 146 DGFQINVKKLEALITSKTKAIILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFY-EDFVPMATLAGMPE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 237 RTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikRMDDpecyfNSLPKELEVKR 316
Cdd:PRK06348 225 RTITFGSFSKDFAMTGWRIGYVIAPDYIIETAKIINEGICFSAPTISQRAAIYAL-----KHRD-----TIVPLIKEEFQ 294
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56713256 317 DRMVRLLESVGLKP----IVPDGGYFIIADVSllDPDLSDMknnepydyKFVKWMTKHKKLSAIPVSAF 381
Cdd:PRK06348 295 KRLEYAYKRIESIPnlslHPPKGSIYAFINIK--KTGLSSV--------EFCEKLLKEAHVLVIPGKAF 353
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
22-338 |
2.95e-54 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 184.55 E-value: 2.95e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 22 FTKLAAD-PSVVNLGQGFPDISPPTYVKEelskiAAIDSLNQ----YTRGFGHPSLVKALS-YLYEKlYQKQIDSNKEIL 95
Cdd:PRK07682 12 FFDLAANmEGVISLGVGEPDFVTPWNVRE-----ASIRSLEQgytsYTANAGLLELRQEIAkYLKKR-FAVSYDPNDEII 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 96 VTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTK 175
Cdd:PRK07682 86 VTVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPVPVATTLE---------NEFKVQPAQIEAAITAKTK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 176 AIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGnKHLKIATFPGMWERTITIGSAGKTFSVTGWKL 255
Cdd:PRK07682 157 AILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDE-AYTSFASIKGMRERTILISGFSKGFAMTGWRL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 256 GWSIGPNHLIKHLQTVQQNTIYTCATPLQ----EALAQAfwidikrMDDPECYFNSLPKelevKRDRMVRLLESVGLKPI 331
Cdd:PRK07682 236 GFIAAPVYFSEAMLKIHQYSMMCAPTMAQfaalEALRAG-------NDDVIRMRDSYRK----RRNFFVTSFNEIGLTCH 304
|
....*..
gi 56713256 332 VPDGGYF 338
Cdd:PRK07682 305 VPGGAFY 311
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
31-398 |
8.51e-54 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 182.50 E-value: 8.51e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 31 VVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQA 110
Cdd:pfam00155 3 KINLGSNEYLGDTLPAVAKAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSPVLKLDREAAVVFGSGAGANIEALIFL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 111 LIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLrskpvygkrWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVY 190
Cdd:pfam00155 83 LANPGDAILVPAPTYASYIRIARLAGGEVVRYPL---------YDSNDFHLDFDALEAALKEKPKVVLHTSPHNPTGTVA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 191 NREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF--PGMWerTITIGSAGKTFSVTGWKLGWSIGPNHLIKHL 268
Cdd:pfam00155 154 TLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRALlaEGPN--LLVVGSFSKAFGLAGWRVGYILGNAAVISQL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 269 QTVQQNTIYTcaTPLQEALAQAfwidikrMDDPE---CYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFiiadvSL 345
Cdd:pfam00155 232 RKLARPFYSS--THLQAAAAAA-------LSDPLlvaSELEEMRQRIKERRDYLRDGLQAAGLSVLPSQAGFF-----LL 297
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 56713256 346 LDPDLSDMKnnepydyKFVKWMTKHKKLSAIPVSAFCNSEtksqfekFVRFCF 398
Cdd:pfam00155 298 TGLDPETAK-------ELAQVLLEEVGVYVTPGSSPGVPG-------WLRITV 336
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
22-416 |
7.97e-51 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 175.84 E-value: 7.97e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 22 FTKLAADPSVVNLGQGFPDISPPTYVKEElSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVTVGAY 101
Cdd:PRK08361 26 FERASKMENVISLGIGEPDFDTPKNIKEA-AKRALDEGWTHYTPNAGIPELREAIAEYYKKFYGVDVDVD-NVIVTAGAY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 102 GSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTKAIILNT 181
Cdd:PRK08361 104 EATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREE---------NEFQPDPDELLELITKRTRMIVINY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 182 PHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGmwERTITIGSAGKTFSVTGWKLGWSIGP 261
Cdd:PRK08361 175 PNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPMIKYAP--DNTILANSFSKTFAMTGWRLGFVIAP 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 262 NHLIKHLQTVQQNTIYTCATPLQ----EAL-AQAFWIDIKRMddpecyfnslpKELEVKRDRMV--RLLESVGLKPIVPD 334
Cdd:PRK08361 253 EQVIKDMIKLHAYIIGNVASFVQiagiEALrSKESWKAVEEM-----------RKEYNERRKLVlkRLKEMPHIKVFEPK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 335 GGYFIIADVSLLdpdlsDMKNNEpydykFVKWMTKHKKLSAIPVSAFcnsetKSQFEKFVRFCF-IKKDSTLDAAEEIIK 413
Cdd:PRK08361 322 GAFYVFANIDET-----GMSSED-----FAEWLLEKARVVVIPGTAF-----GKAGEGYIRISYaTSKEKLIEAMERMEK 386
|
...
gi 56713256 414 AWS 416
Cdd:PRK08361 387 ALE 389
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
33-414 |
1.51e-46 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 164.64 E-value: 1.51e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 33 NLGQgfPDISPPTYVKEELSKIAaiDSLNQYTRGFGHPSLVKALSYLYEKLyqkQIDSNKE-ILVTVGAYGSLFNTIQAL 111
Cdd:PRK07568 36 NIGQ--PDIKTPEVFFEAIKNYD--EEVLAYSHSQGIPELREAFAKYYKKW---GIDVEPDeILITNGGSEAILFAMMAI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 112 IDEGDEVILIVPFYDCYEPMVRMAGATPVfiPLRSKPVYGKRWSSsdwtldPQELESKFNSKTKAIILNTPHNPLGKVYN 191
Cdd:PRK07568 109 CDPGDEILVPEPFYANYNGFATSAGVKIV--PVTTKIEEGFHLPS------KEEIEKLITPKTKAILISNPGNPTGVVYT 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 192 REELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPN-HLIKHLQT 270
Cdd:PRK07568 181 KEELEMLAEIAKKHDLFLISDEVYREFVYDGLKYTSALSLEGLEDRVIIIDSVSKRYSACGARIGCLISKNkELIAAAMK 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 271 VQQNTIyTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMVRLLESV-GLKPIVPDGGYFIIADVSLLDPD 349
Cdd:PRK07568 261 LCQARL-SPPTLEQIGAAAL-------LDTPESYFDEVREEYKKRRDILYEELNKIpGVVCEKPKGAFYIIAKLPVDDAE 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 350 lsdmknnepydyKFVKWMTKH-----KKLSAIPVSAFCNSETKSQFEkfVRFCFIKKDSTLDAAEEIIKA 414
Cdd:PRK07568 333 ------------DFAKWLLTDfnyngETVMVAPASGFYATPGLGKNE--IRIAYVLNEEDLKRAMEILKE 388
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
26-339 |
4.66e-44 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 158.36 E-value: 4.66e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 26 AADPSVVNLGQGFPDISPPTYVKEelSKIAAIDS-LNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVTVGAYGSL 104
Cdd:PRK06107 30 AAGRSIVDLTVGEPDFDTPDHIKQ--AAVAAIERgETKYTLVNGTPALRKAIIAKLERRNGLHYADN-EITVGGGAKQAI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 105 FNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsSSDWTLDPQELESKFNSKTKAIILNTPHN 184
Cdd:PRK06107 107 FLALMATLEAGDEVIIPAPYWVSYPDMVLANDGTPVIVACPE---------EQGFKLTPEALEAAITPRTRWLILNAPSN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 185 PLGKVYNREELQVIADLCIKY-DTLCISDEVYEWLVYSG--NKHLkIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGP 261
Cdd:PRK06107 178 PTGAVYSRAELRALADVLLRHpHVLVLTDDIYDHIRFDDepTPHL-LAAAPELRDRVLVTNGVSKTYAMTGWRIGYAAGP 256
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56713256 262 NHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDikrmddpECYFNSLPKELEVKRDRMVRLLESV-GLKPIVPDGGYFI 339
Cdd:PRK06107 257 ADLIAAINKLQSQSSSCPSSISQAAAAAALNGD-------QSFVTESVAVYKQRRDYALALLNAIpGLSCLVPDGAFYL 328
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
25-279 |
1.79e-43 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 156.39 E-value: 1.79e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 25 LAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSylyEKLYQK---QIDSNKEILVTVGAY 101
Cdd:PRK05957 23 IRENPGTISLGQGVVSYPPPPEAIEALNNFLANPENHKYQAVQGIPPLLEAIT---QKLQQDngiELNNEQAIVVTAGSN 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 102 GSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPlrskpvygkrwSSSDWTLDPQELESKFNSKTKAIILNT 181
Cdd:PRK05957 100 MAFMNAILAITDPGDEIILNTPYYFNHEMAITMAGCQPILVP-----------TDDNYQLQPEAIEQAITPKTRAIVTIS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 182 PHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGP 261
Cdd:PRK05957 169 PNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDGVKHFSPGSIPGSGNHTISLYSLSKAYGFASWRIGYMVIP 248
|
250
....*....|....*...
gi 56713256 262 NHLIKHLQTVqQNTIYTC 279
Cdd:PRK05957 249 IHLLEAIKKI-QDTILIC 265
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
25-415 |
5.00e-43 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 154.72 E-value: 5.00e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 25 LAADPS----VVNLGQGFPDISP----------PTYVKEelskiAAIDSLNQ----YTRGFGHPSLVKALSYLYEKLYQK 86
Cdd:PRK06108 6 RALPESgireVANAGRGREGVLPlwfgesdlptPDFIRD-----AAAAALADgetfYTHNLGIPELREALARYVSRLHGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 87 QIDSnKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskpvYGkrwsSSDWTLDPQEL 166
Cdd:PRK06108 81 ATPP-ERIAVTSSGVQALMLAAQALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLD----FG----GGGWTLDLDRL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 167 ESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGN----KHLKIATfPGmwERTITIG 242
Cdd:PRK06108 152 LAAITPRTRALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGgrapSFLDIAE-PD--DRIIFVN 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 243 SAGKTFSVTGWKLGWSIGPNHLIKHL-QTVQQNTiyTC-ATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRDRMV 320
Cdd:PRK06108 229 SFSKNWAMTGWRLGWLVAPPALGQVLeKLIEYNT--SCvAQFVQRAAVAA-------LDEGEDFVAELVARLRRSRDHLV 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 321 RLLESV-GLKPIVPDGGYFIIADVslldPDLSDMKnnepydyKFVKWMTKHKKLSAIPVSAFcnsetKSQFEKFVRFCFI 399
Cdd:PRK06108 300 DALRALpGVEVAKPDGAMYAFFRI----PGVTDSL-------ALAKRLVDEAGLGLAPGTAF-----GPGGEGFLRWCFA 363
|
410
....*....|....*.
gi 56713256 400 KKDSTLDAAEEIIKAW 415
Cdd:PRK06108 364 RDPARLDEAVERLRRF 379
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
26-398 |
5.04e-39 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 144.43 E-value: 5.04e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 26 AADPSVVNLGQGFPDISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKeILVTVGAYGSLF 105
Cdd:PRK07337 27 RAGRDIIHMGIGEPDFTAPEPVVEAAAR-ALRRGVTQYTSALGLAPLREAIAAWYARRFGLDVAPER-IVVTAGASAALL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 106 NTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPlrSKPVygKRWSssdwtLDPQELESKFNSKTKAIILNTPHNP 185
Cdd:PRK07337 105 LACLALVERGDEVLMPDPSYPCNRHFVAAAEGRPVLVP--SGPA--ERFQ-----LTAADVEAAWGERTRGVLLASPSNP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 186 LGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIAtfpgMWERTITIGSAGKTFSVTGWKLGWSIGPNHLI 265
Cdd:PRK07337 176 TGTSIAPDELRRIVEAVRARGGFTIVDEIYQGLSYDAAPVSALS----LGDDVITINSFSKYFNMTGWRLGWLVVPEALV 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 266 KHLQTVQQNtIYTCATPL-QEALAQAFwidikrmdDPECY--FNSLPKELEVKRDRMVRLLESVGLK-PIVPDGGYFIIA 341
Cdd:PRK07337 252 GTFEKLAQN-LFICASALaQHAALACF--------EPDTLaiYERRRAEFKRRRDFIVPALESLGFKvPVMPDGAFYVYA 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 56713256 342 DVS-LLDPDLSDmknnepyDYKFVKWMTKHKKLSAIPVSAFCNSETksqfEKFVRFCF 398
Cdd:PRK07337 323 DCRgVAHPAAGD-------SAALTQAMLHDAGVVLVPGRDFGPHAP----RDYIRLSY 369
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
3-414 |
1.38e-38 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 143.41 E-value: 1.38e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 3 LKFTNAKRIEGLDSNVWIEFT-----KLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGfGHPSLVKALS 77
Cdd:PRK07681 1 MTYTLATRMKAFQSSIFSELGaykkeKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLS-GIQEFHEAVT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 78 YLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssS 157
Cdd:PRK07681 80 EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKE---------N 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 158 DWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWER 237
Cdd:PRK07681 151 DFLPDLELIPEEIADKAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 238 TITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikRMDDPECYFNslpKEL-EVKR 316
Cdd:PRK07681 231 GVEINSLSKSYSLAGSRIGYMIGNEEIVRALTQFKSNTDYGVFLPIQKAACAAL-----RNGAAFCEKN---RGIyQERR 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 317 DRMVRLLESVGLKPIVPDGGYFIIADVslldPDLSDmknnepyDYKFVKWMTKHKKLSAIPVSAFcnsetKSQFEKFVRF 396
Cdd:PRK07681 303 DTLVDGFRTFGWNVDKPAGSMFVWAEI----PKGWT-------SLSFAYALMDRANVVVTPGHAF-----GPHGEGFVRI 366
|
410
....*....|....*...
gi 56713256 397 CFIKKDSTLDAAEEIIKA 414
Cdd:PRK07681 367 ALVQDEEVLQQAVENIRN 384
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
31-339 |
2.36e-36 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 137.25 E-value: 2.36e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 31 VVNLGQGFP---DISPPTYVKEELSKiAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSnKEILVTVGAYGSLFNT 107
Cdd:PRK08363 32 VIRLNIGDPvkfDFQPPEHMKEAYCR-AIKEGHNYYGPSEGLPELREAIVKREKRKNGVDITP-DDVRVTAAVTEALQLI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 108 IQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIplrskpvygKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLG 187
Cdd:PRK08363 110 FGALLDPGDEILIPGPSYPPYTGLVKFYGGVPVEY---------RTIEEEGWQPDIDDIRKKITEKTKAIAVINPNNPTG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 188 KVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGnKHLKIATFPGMwERTITIGSAGKTFSVTGWKLGWS--IGPNhli 265
Cdd:PRK08363 181 ALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEG-KHVSPGSLTKD-VPVIVMNGLSKVYFATGWRLGYIyfVDPE--- 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 266 KHLQTVQQNT-----IYTCA-TPLQEALAQAFwidIKRMDdpecYFNSLPKELEVKRDRMV-RLLESVGLKPIVPDGGYF 338
Cdd:PRK08363 256 GKLAEVREAIdklarIRLCPnTPAQFAAIAGL---TGPMD----YLEEYMKKLKERRDYIYkRLNEIPGISTTKPQGAFY 328
|
.
gi 56713256 339 I 339
Cdd:PRK08363 329 I 329
|
|
| MalY |
COG1168 |
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ... |
63-262 |
6.84e-36 |
|
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];
Pssm-ID: 440782 Cd Length: 387 Bit Score: 135.60 E-value: 6.84e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 63 YTrgFGHPSLVKALSYLYEKLYQKQIDsnKE-ILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVF 141
Cdd:COG1168 62 YT--APPDEYYEAIIDWLKRRHGWEID--PEwIVFTPGVVPGLALAIRAFTEPGDGVLIQTPVYPPFFKAIENNGRELVE 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 142 IPLRskpvygkrWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYS 221
Cdd:COG1168 138 NPLI--------LEDGRYRIDFDDLEAKLDPGVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLP 209
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 56713256 222 GNKHLKIATF-PGMWERTITIGSAGKTFSVTGWKLGWSIGPN 262
Cdd:COG1168 210 GHKHTPFASLsEEAADRTITLTSPSKTFNLAGLKASYAIIPN 251
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
37-381 |
1.43e-35 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 134.94 E-value: 1.43e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 37 GFPDISPPTYVKEELSKIA--AIDSLNQYTRGFGHPSLVKALSylyEKLYQKQ-IDSNKE-ILVTVGAYGSLFNTIQALI 112
Cdd:PRK06836 41 GNPSVPPPAAVKEALRELAeeEDPGLHGYMPNAGYPEVREAIA---ESLNRRFgTPLTADhIVMTCGAAGALNVALKAIL 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 113 DEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwsssDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNR 192
Cdd:PRK06836 118 NPGDEVIVFAPYFVEYRFYVDNHGGKLVVVPTDTD----------TFQPDLDALEAAITPKTKAVIINSPNNPTGVVYSE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 193 EELQVIADL----CIKYDT--LCISDEVYEWLVYSGnkhLKIATFPGMWERTITIGSAGKTFSVTGWKLGWsIGPNHLIK 266
Cdd:PRK06836 188 ETLKALAALleekSKEYGRpiYLISDEPYREIVYDG---AEVPYIFKYYDNSIVVYSFSKSLSLPGERIGY-IAVNPEME 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 267 HLQT-----VQQNTI--YTCATPL-QEALAQAfwIDIKRmdDPECYfnslpkelEVKRDRMVRLLESVGLKPIVPDGGYF 338
Cdd:PRK06836 264 DADDlvaalVFANRIlgFVNAPALmQRVVAKC--LDATV--DVSIY--------KRNRDLLYDGLTELGFECVKPQGAFY 331
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 56713256 339 IIadVSLLDPDlsdmknnepyDYKFVKWMTKHKKLsAIPVSAF 381
Cdd:PRK06836 332 LF--PKSPEED----------DVAFCEKAKKHNLL-LVPGSGF 361
|
|
| C_S_lyase_PatB |
TIGR04350 |
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of ... |
67-351 |
2.80e-34 |
|
putative C-S lyase; Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).
Pssm-ID: 275146 Cd Length: 384 Bit Score: 131.29 E-value: 2.80e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 67 FGHP----SLVKALSYLYEKLYQKQIDsNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFI 142
Cdd:TIGR04350 56 FGYTlppdSLYAAVINWLAQRHGWQID-PEDIVFLPGVVPSLFAAVRALTAPGEGVIVQTPVYPPFLSAVKSNGRELVLN 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 143 PLRskpvygkrWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSG 222
Cdd:TIGR04350 135 PLK--------LDEGRYRFDLEDLEDAITEKARLLLLCSPHNPVGRVWTREELTRLAELCLRHNVVVVSDEIHADLVYPP 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 223 NKHLKIAT-FPGMWERTITIGSAGKTFSVTGWKLGWSIGPNH-LIKHLQTVQQNTIYTCATPLQEALAQAFWidikrmDD 300
Cdd:TIGR04350 207 NKHIPLASlSPEPAERTVTLLSPGKTFNIAGLNISFAIIPNPeLRRAFQEAAQRVHIQHGNLFGYVAFEAAY------RD 280
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 56713256 301 PECYFNSLPKELEVKRDRMVRLL--ESVGLKPIVPDGGYFIIADVSLL---DPDLS 351
Cdd:TIGR04350 281 GEPWLDALLAYLRGNRDLVEEFIakRLPQIRVRPPEATYLAWLDCRALgldDADLR 336
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
26-349 |
6.50e-34 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 130.17 E-value: 6.50e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 26 AADPSVVNLGQGFPDISPPTYVKEelSKIAAIDSLN-QYTRGFGHPSLVKALSYLYEKLYQKQIDSNKeILVTVGAYGSL 104
Cdd:PRK08960 29 AAGHDVIHLEIGEPDFTTAEPIVA--AGQAALAAGHtRYTAARGLPALREAIAGFYAQRYGVDVDPER-ILVTPGGSGAL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 105 FNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsSSDWTLDPQELESKFNSKTKAIILNTPHN 184
Cdd:PRK08960 106 LLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGP---------DSRYQLTPALVERHWNADTVGALVASPAN 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 185 PLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSgnkhLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHL 264
Cdd:PRK08960 177 PTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYG----VDAASVLEVDDDAFVLNSFSKYFGMTGWRLGWLVAPPAA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 265 IKHLQTVQQNTIYTCATPLQEALAQAFwidikrmdDPECY--FNSLPKELEVKRDRMVRLLESVGLK-PIVPDGGYFIIA 341
Cdd:PRK08960 253 VPELEKLAQNLYISASTPAQHAALACF--------EPETLaiLEARRAEFARRRDFLLPALRELGFGiAVEPQGAFYLYA 324
|
....*...
gi 56713256 342 DVSLLDPD 349
Cdd:PRK08960 325 DISAFGGD 332
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
25-398 |
6.54e-32 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 126.10 E-value: 6.54e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 25 LAADPSVVNLGQGFPDIS--PPTYVKEELSKIAAID--SLNQYTRGFGHPSLVKALSylyEKLYQKQID-SNKEILVTVG 99
Cdd:COG1167 102 LEAAPGVIDLGSGAPDPDlfPLAALRRALRRALRRLppALLGYGDPQGLPELREAIA---RYLARRGVPaSPDQILITSG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 100 AYGSLFNTIQALIDEGDEVILIVPfydCYEPMV---RMAGATPVFIPLRSkpvYGkrwsssdwtLDPQELESKF-NSKTK 175
Cdd:COG1167 179 AQQALDLALRALLRPGDTVAVESP---TYPGALaalRAAGLRLVPVPVDE---DG---------LDLDALEAALrRHRPR 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 176 AIILnTP--HNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMwERTITIGSAGKTFSvTGW 253
Cdd:COG1167 244 AVYV-TPshQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAP-GRVIYIGSFSKTLA-PGL 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 254 KLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQafWID-------IKRMddpecyfnslPKELEVKRDRMVRLLESV 326
Cdd:COG1167 321 RLGYLVAPGRLIERLARLKRATDLGTSPLTQLALAE--FLEsghydrhLRRL----------RREYRARRDLLLAALARH 388
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 56713256 327 ---GLKPIVPDGGYFIIADvslLDPDLSDMknnepydyKFVKWMTKHkKLSAIPVSAFCNSEtksQFEKFVRFCF 398
Cdd:COG1167 389 lpdGLRVTGPPGGLHLWLE---LPEGVDAE--------ALAAAALAR-GILVAPGSAFSADG---PPRNGLRLGF 448
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
22-414 |
4.93e-30 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 119.75 E-value: 4.93e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 22 FTKLAADPSVVNLGQGFPDISP--PTYVKEELSKIAAIDS--LNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVT 97
Cdd:TIGR01265 24 KVKPNPEKPVIPLSHGDPSVFGnlRTDPEAEEAVKDALRSgkFNGYAPSVGALAAREAVAEYLSSDLPGKLTAD-DVVLT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 98 VGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGatpvfIPLRskpvYGKRWSSSDWTLDPQELESKFNSKTKAI 177
Cdd:TIGR01265 103 SGCSQAIEICIEALANPGANILVPRPGFPLYDTRAAFSG-----LEVR----LYDLLPEKDWEIDLDGLESLADEKTVAI 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 178 ILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERtITIGSAGKTFSVTGWKLGW 257
Cdd:TIGR01265 174 VVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPMASFASIVPV-LSLGGISKRWVVPGWRLGW 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 258 SI--GPNHLIKH--LQTVQQNTIYTC--ATPLQEALAqafwiDIKRmDDPECYFNSLPKELevKRDRMV---RLLESVGL 328
Cdd:TIGR01265 253 IIihDPHGIFRDtvLQGLKNLLQRILgpATIVQGALP-----DILE-NTPQEFFDGKISVL--KSNAELcyeELKDIPGL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 329 KPIVPDGGYFIIADVSL-LDPDLSDmknnepyDYKFVKWMTKHKKLSAIPVSAFcnsetksQFEKFVRFCFIKKDSTLDA 407
Cdd:TIGR01265 325 VCPKPEGAMYLMVKLELeLFPEIKD-------DVDFCEKLAREESVICLPGSAF-------GLPNWVRITITVPESMLEE 390
|
....*..
gi 56713256 408 AEEIIKA 414
Cdd:TIGR01265 391 ACSRIKE 397
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
4-343 |
1.88e-29 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 118.09 E-value: 1.88e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 4 KFTNAKRIEGLDSNVWIEFTKLAADP-----SVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSY 78
Cdd:PRK09276 1 MMKLADRIKNLPPYLFAEIDKKKAEKiargvDVISLGIGDPDLPTPDHIIEAMCKAVEDPENHQYPSYEGMLEFRKAVAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 79 LYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRS----KPvygkrw 154
Cdd:PRK09276 81 WYKRRFGVELDPETEVISLIGSKEGIAHIPLAFVNPGDVVLVPDPGYPVYKIGTIFAGGEPYFMPLKEengfLP------ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 155 sssDWTLDPQELESKfnskTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGM 234
Cdd:PRK09276 155 ---DLDAIPEDVAKK----AKLMFINYPNNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDGYKPPSFLEVPGA 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 235 WERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEAlaqafwiDIKRMDDPECYFNSLPKELEV 314
Cdd:PRK09276 228 KDVGIEFHSLSKTYNMTGWRIGFAVGNADLIAGLGKVKSNVDSGVFQAIQEA-------GIAALNGPQEVVEELRKIYQE 300
|
330 340
....*....|....*....|....*....
gi 56713256 315 KRDRMVRLLESVGLKPIVPDGGYFIIADV 343
Cdd:PRK09276 301 RRDILVEGLRKLGLEVEPPKATFYVWAPV 329
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
43-354 |
1.23e-28 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 116.04 E-value: 1.23e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 43 PPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQkQIDSNKE------ILVTVGAYGSLFNTIQALIDEGD 116
Cdd:PTZ00433 51 TPAIQTKALVEAVDSQECNGYPPTVGSPEAREAVATYWRNSFV-HKESLKStikkdnVVLCSGVSHAILMALTALCDEGD 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 117 EVILIVPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQ 196
Cdd:PTZ00433 130 NILVPAPGFPHYETVCKAYGIEMRFYNCRP---------EKDWEADLDEIRRLVDDRTKALIMTNPSNPCGSNFSRKHVE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 197 VIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAgKTFSVTGWKLGWSI-------GPNhLIKHLQ 269
Cdd:PTZ00433 201 DIIRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVPRVILGGTA-KNLVVPGWRLGWLLlvdphgnGGD-FLDGMK 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 270 TVQQNTIYTCATpLQEALAQAFwidikrMDDPECYFNSLPKELEVKRDRMVRLLES-VGLKPIVPDGGYFIIA--DVSLL 346
Cdd:PTZ00433 279 RLGMLVCGPCSV-VQAALGEAL------LNTPQEHLEQIVAKLEEGAMVLYNHIGEcIGLSPTMPRGSMFLMSrlDLEKF 351
|
....*...
gi 56713256 347 DPDLSDMK 354
Cdd:PTZ00433 352 RDIKSDVE 359
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
28-381 |
6.79e-28 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 113.72 E-value: 6.79e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 28 DPSVvnlgqgFPDISPPTYVKEELSKiaAIDS--LNQYTRGFGHPSLVKALSYLYEKLyQKQIDSNkEILVTVGAYGSLF 105
Cdd:TIGR01264 40 DPTV------FGNLPTDPEVMQAMKD--SLDSgkYNGYAPTVGALSAREAIASYYHNP-DGPIEAD-DVVLCSGCSHAIE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 106 NTIQALIDEGDEVILIVPFYDCYEPMVRMAGatpvfipLRSKPvYGKRwSSSDWTLDPQELESKFNSKTKAIILNTPHNP 185
Cdd:TIGR01264 110 MCIAALANAGQNILVPRPGFPLYETLAESMG-------IEVKL-YNLL-PDKSWEIDLKQLESLIDEKTAALIVNNPSNP 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 186 LGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERtITIGSAGKTFSVTGWKLGWSIGPNH-- 263
Cdd:TIGR01264 181 CGSVFSRQHLEEILAVAERQCLPIIADEIYGDMVFSGATFEPLASLSSTVPI-LSCGGLAKRWLVPGWRLGWIIIHDRrg 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 264 ----LIKHLQTVQQNTIYTCaTPLQEALAQAFwidikrMDDPECYFNSLPKELEVKRDRMVRLL-ESVGLKPIVPDGGYF 338
Cdd:TIGR01264 260 ilrdIRDGLVKLSQRILGPC-TIVQGALPSIL------LRTPQEYFDGTLSVLESNAMLCYGALaAVPGLRPVMPSGAMY 332
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 56713256 339 IIADVSLldPDLSDMKNnepyDYKFVKWMTKHKKLSAIPVSAF 381
Cdd:TIGR01264 333 MMVGIEM--EHFPEFKN----DVEFTERLVAEQSVFCLPGSCF 369
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
26-338 |
3.41e-26 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 108.89 E-value: 3.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 26 AADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSnKEILVTVGAYGSLF 105
Cdd:PRK07550 26 GADGPLIDLSQAVPGYPPPPELLRALAEAAADPAAHLYGPVEGLPELREAYAAHYSRLYGAAISP-EQVHITSGCNQAFW 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 106 NTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPvygkrwsssDWTLDPQELESKFNSKTKAIILNTPHNP 185
Cdd:PRK07550 105 AAMVTLAGAGDEVILPLPWYFNHKMWLDMLGIRPVYLPCDEGP---------GLLPDPAAAEALITPRTRAIALVTPNNP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 186 LGKVYNREELQVIADLCIKYDTLCISDEVY-EWLVYSGNKHLKIATfPGmWERT-ITIGSAGKTFSVTGWKLGWSIGPNH 263
Cdd:PRK07550 176 TGVVYPPELLHELYDLARRHGIALILDETYrDFDSGGGAPHDLFAD-PD-WDDTlVHLYSFSKSYALTGHRVGAVVASPA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 264 LIKHLQTVqQNTIYTCATPL-QEALAQAF-----WIDIKRMddpecyfnslpkELEVKRDRMVRLLESVGLKPIVPDGGY 337
Cdd:PRK07550 254 RIAEIEKF-MDTVAICAPRIgQIAVAWGLpnladWRAGNRA------------EIARRRDAFRAVFARLPGWELLASGAY 320
|
.
gi 56713256 338 F 338
Cdd:PRK07550 321 F 321
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
23-338 |
3.89e-26 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 108.86 E-value: 3.89e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 23 TKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYG 102
Cdd:PRK08068 26 KKVAEGHDVINLGQGNPDQPTPEHIVEALQEAAENPANHKYSPFRGYPFLKEAAADFYKREYGVTLDPETEVAILFGGKA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 103 SLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTKAIILNTP 182
Cdd:PRK08068 106 GLVELPQCLMNPGDTILVPDPGYPDYLSGVALARAQFETMPLIAE---------NNFLPDYTKIPEEVAEKAKLMYLNYP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 183 HNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPN 262
Cdd:PRK08068 177 NNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFDGQKPVSFLQTPGAKDVGIELYTLSKTFNMAGWRVAFAVGNE 256
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 56713256 263 HLIKHLQTVQQNTIYTCATPLQEALAQAFwidikrMDDPECyFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYF 338
Cdd:PRK08068 257 SVIEAINLLQDHLFVSLFGAIQDAAIEAL------LSDQSC-VAELVARYESRRNAFISACREIGWEVDAPKGSFF 325
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
68-288 |
1.33e-24 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 104.25 E-value: 1.33e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 68 GHPSLVKALSylyeKLYQKQIDSNkeILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSK 147
Cdd:PRK07324 63 GSPEFKEAVA----SLYQNVKPEN--ILQTNGATGANFLVLYALVEPGDHVISVYPTYQQLYDIPESLGAEVDYWQLKEE 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 148 pvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNkhlk 227
Cdd:PRK07324 137 ---------NGWLPDLDELRRLVRPNTKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDEDGS---- 203
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 56713256 228 IATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQ-NTIytCATPLQEALA 288
Cdd:PRK07324 204 TPSIADLYEKGISTNSMSKTYSLPGIRVGWIAANEEVIDILRKYRDyTMI--CAGVFDDMLA 263
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
88-352 |
4.31e-24 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 103.31 E-value: 4.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 88 IDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVygkrwsSSDWTLDPQELE 167
Cdd:PRK06207 99 VDAADELIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEGEMVPVQLDYLSA------DKRAGLDLDQLE 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 168 SKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKT 247
Cdd:PRK06207 173 EAFKAGVRVFLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDGTSYTHLRALPIDPENVITIMGPSKT 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 248 FSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFwidikrmDDPECYFNSLPKELEVKRDRMVRLLESV- 326
Cdd:PRK06207 253 ESLSGYRLGVAFGSPAIIDRMEKLQAIVSLRAAGYSQAVLRTWF-------SEPDGWMKDRIARHQAIRDDLLRVLRGVe 325
|
250 260
....*....|....*....|....*.
gi 56713256 327 GLKPIVPDGGYFIIADVSLLDPDLSD 352
Cdd:PRK06207 326 GVFVRAPQAGSYLFPRLPRLAVSLHD 351
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
43-343 |
2.37e-23 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 99.82 E-value: 2.37e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 43 PPTYVKEELSkiAAIDSLNQYTRGfGHPSLVKALS-YLyeklyqkQIDSNkEILVTVGAYGSLFNTIQALIDEGDEVILI 121
Cdd:COG0079 27 PPPKVLEAIA--AALDALNRYPDP-DATALREALAeYY-------GVPPE-QVLVGNGSDELIQLLARAFLGPGDEVLVP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 122 VPFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsssDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADL 201
Cdd:COG0079 96 EPTFSEYPIAARAAGAEVVEVPLDE-----------DFSLDLDALLAAITERTDLVFLCNPNNPTGTLLPREELEALLEA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 202 CiKYDTLCISDEVY-EwlvYSGNKH----LkIATFPGMwertITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQntI 276
Cdd:COG0079 165 L-PADGLVVVDEAYaE---FVPEEDsalpL-LARYPNL----VVLRTFSKAYGLAGLRLGYAIASPELIAALRRVRG--P 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56713256 277 YTCATPLQEALAQAfwidikrMDDPEcYFNSLPKELEVKRDRMVRLLESVGLKPiVPDGGYFIIADV 343
Cdd:COG0079 234 WNVNSLAQAAALAA-------LEDRA-YLEETRARLRAERERLAAALRALGLTV-YPSQANFVLVRV 291
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
26-290 |
2.62e-23 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 100.91 E-value: 2.62e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 26 AADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLF 105
Cdd:PRK09148 27 AAGADIIDLGMGNPDLPTPQHIVDKLCETAQDPRTHRYSASKGIPGLRRAQAAYYARRFGVKLNPDTQVVATLGSKEGFA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 106 NTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYgkrwsssdwtLDPQELESKFN-SKTKAIILNTPHN 184
Cdd:PRK09148 107 NMAQAITAPGDVILCPNPSYPIHAFGFIMAGGVIRSVPAEPDEEF----------FPALERAVRHSiPKPIALIVNYPSN 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 185 PLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHL 264
Cdd:PRK09148 177 PTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDGNPPPSVLQVPGAKDVTVEFTSMSKTFSMAGWRMGFAVGNERL 256
|
250 260
....*....|....*....|....*.
gi 56713256 265 IKHLQTVQQNTIYTCATPLQEALAQA 290
Cdd:PRK09148 257 IAALTRVKSYLDYGAFTPIQVAATAA 282
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
107-266 |
4.50e-23 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 100.27 E-value: 4.50e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 107 TIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFipLRSKPvygkrwsSSDWTLDPQELESKFNSKTKAIILNTPHNPL 186
Cdd:PRK09265 111 AMQALLNNGDEVLVPAPDYPLWTAAVSLSGGKPVH--YLCDE-------EAGWFPDLDDIRSKITPRTKAIVIINPNNPT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 187 GKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF-PGMWerTITIGSAGKTFSVTGWKLGWSI--GPNH 263
Cdd:PRK09265 182 GAVYSKELLEEIVEIARQHNLIIFADEIYDKILYDGAVHISIASLaPDLL--CVTFNGLSKAYRVAGFRVGWMVlsGPKK 259
|
...
gi 56713256 264 LIK 266
Cdd:PRK09265 260 HAK 262
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
31-414 |
5.03e-23 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 99.78 E-value: 5.03e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 31 VVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQA 110
Cdd:PRK08175 31 IIDFSMGNPDGPTPPHIVEKLCEVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVDIDPESEAIVTIGSKEGLAHLMLA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 111 LIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLrskpVYGKRWSSsdwtldpqELESKFNS---KTKAIILNTPHNPLG 187
Cdd:PRK08175 111 TLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPL----VEGVDFFN--------ELERAIREsypKPKMMILGFPSNPTA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 188 KVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKH 267
Cdd:PRK08175 179 QCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGAKDVAVEFFTLSKSYNMAGWRIGFMVGNPELVSA 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 268 LQTVQQNTIYTCATPLQEAlaqafwiDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSlld 347
Cdd:PRK08175 259 LARIKSYHDYGTFTPLQVA-------AIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIP--- 328
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56713256 348 pdlsdmknnEPY----DYKFVKWMTKHKKLSAIPVSAFcnsetKSQFEKFVRFCFIKKDSTLDAAEEIIKA 414
Cdd:PRK08175 329 ---------EPYaamgSLEFAKKLLNEAKVCVSPGIGF-----GDYGDTHVRFALIENRDRIRQAIRGIKA 385
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
107-259 |
6.18e-23 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 100.97 E-value: 6.18e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 107 TIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHNPL 186
Cdd:PRK13355 224 SMSALLDDGDEVLIPSPDYPLWTACVNLAGGTAVHYRCDEQ---------SEWYPDIDDIRSKITSRTKAIVIINPNNPT 294
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56713256 187 GKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF-PGMWerTITIGSAGKTFSVTGWKLGWSI 259
Cdd:PRK13355 295 GALYPREVLQQIVDIAREHQLIIFSDEIYDRLVMDGLEHTSIASLaPDLF--CVTFSGLSKSHMIAGYRIGWMI 366
|
|
| PRK05942 |
PRK05942 |
aspartate aminotransferase; Provisional |
1-327 |
7.62e-23 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 180317 Cd Length: 394 Bit Score: 99.41 E-value: 7.62e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 1 MSLKFTN-AKRIEGLDSNVWIEFTKLAADP-----SVVNLGQGFPDISPPTYVKEelskiAAIDSL-NQYTRGF----GH 69
Cdd:PRK05942 1 MSLDWITpADRLQALPPYVFARLDELKARAreqglDLIDLGMGNPDGAAPQPVIE-----AAIAALaDPQNHGYppfeGT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 70 PSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCY--EPMVrmAGATPVFIPLRSK 147
Cdd:PRK05942 76 ASFRQAITDWYHRRYGVELDPDSEALPLLGSKEGLTHLALAYVNPGDVVLVPSPAYPAHfrGPLI--AGAQIYPIILKPE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 148 pvygkrwssSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLK 227
Cdd:PRK05942 154 ---------NDWLIDLSSIPEEVAQQAKILYFNYPSNPTTATAPREFFEEIVAFARKYEIMLVHDLCYAELAFDGYQPTS 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 228 IATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIdikrmddPECYFNS 307
Cdd:PRK05942 225 LLEIPGAKDIGVEFHTLSKTYNMAGWRVGFVVGNRHIIQGLRTLKTNLDYGIFSALQKAAETALQL-------PDSYLQQ 297
|
330 340
....*....|....*....|
gi 56713256 308 LPKELEVKRDRMVRLLESVG 327
Cdd:PRK05942 298 VQERYRTRRDFLIQGLGELG 317
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
20-413 |
7.79e-22 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 96.65 E-value: 7.79e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 20 IEFTKLAA-----DPSVVNLGQGFPDISPPTYVKEELSKIAAIDSlnqyTRGF---GHPSLVKALSYLYEKLYQ-KQIDS 90
Cdd:PRK06290 30 IKRAKRAAkekhpDMELIDMGVGEPDEMADESVVEVLCEEAKKPE----NRGYadnGIQEFKEAAARYMEKVFGvKDIDP 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 91 NKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKpvygkrwssSDWTLDPQELESKF 170
Cdd:PRK06290 106 VTEVIHSIGSKPALAMLPSCFINPGDVTLMTVPGYPVTGTHTKYYGGEVYNLPLLEE---------NNFLPDLDSIPKDI 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 171 NSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGnKHLKIATFPGMWERTITIGSAGKTFSV 250
Cdd:PRK06290 177 KEKAKLLYLNYPNNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDG-KPLSFLSVPGAKEVGVEIHSLSKAYNM 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 251 TGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPEcyfnsLPKELEVKRDR----MVRLLESV 326
Cdd:PRK06290 256 TGWRLAFVVGNELIVKAFATVKDNNDSGQFIAIQKAGIYA-------LDHPE-----ITEKIREKYSRrldkLVKILNEV 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 327 GLKPIVPDGGYFIIADVSLLDPDLSDMKNNEpydyKFVKWMTKHKKLSAIPVSAFCNsetksqfekFVRF--CFIKKDst 404
Cdd:PRK06290 324 GFKAEMPGGTFYLYVKAPKGTKSGIKFENAE----EFSQYLIKEKLISTVPWDDAGH---------FLRFsvTFEAKD-- 388
|
....*....
gi 56713256 405 LDAAEEIIK 413
Cdd:PRK06290 389 EEEEDRILE 397
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
31-353 |
1.07e-17 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 84.44 E-value: 1.07e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 31 VVNLGQGFPDISP--PTYVKEELSKIAAIDS--LNQYTRGFGHPSLVKALS-YLYEKL-YQKQIDsnkEILVTVGAYGSL 104
Cdd:PLN00145 54 VLPLGHGDPSAFPcfRTAPEAEDAVAAALRSgkYNSYSTCVGLLPARRAIAeYLSRDLpYELSTD---DIYLTAGCAQAI 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 105 FNTIQALIDEGDEVILIVPFYDCYEpmvrmagATPVFIPLRSKpvYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHN 184
Cdd:PLN00145 131 EIIMSVLAQPGANILLPRPGYPLYE-------ARAVFSGLEVR--HFDLLPERGWEVDLEGVEALADENTVAMVIINPNN 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 185 PLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFpGMWERTITIGSAGKTFSVTGWKLGW--SIGPN 262
Cdd:PLN00145 202 PCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTFGSKPFVPMGVF-GEVAPVLTLGSISKRWVVPGWRLGWiaTCDPN 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 263 HLIKHLQTVQ--QNTIYTCATP---LQEALAQAfwidIKRMDDPecYFNSLPKELEVKRDRMVRLLESV-GLK-PIVPDG 335
Cdd:PLN00145 281 GILKETKVVDsiRNYLNISTDPatfVQGAIPQI----IANTKEE--FFTKTLGLLKETADICYEKIKEIkCITcPHKPEG 354
|
330 340
....*....|....*....|
gi 56713256 336 GYFIIA--DVSLLDPDLSDM 353
Cdd:PLN00145 355 SMFVMVklDLSCLSGIKDDM 374
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
21-344 |
3.50e-17 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 82.49 E-value: 3.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 21 EFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLvKALSYLYEKLyqkqidSNKEILVTVGA 100
Cdd:PRK06225 20 FFDYVFKDKEMIWMGQNTNHLGPHEEVREAMIRCIEEGEYCKYPPPEGFPEL-RELILKDLGL------DDDEALITAGA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 101 YGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATpvfipLRSKPVYGkrwSSSDWTLDPQELESKFNSKTKAIILN 180
Cdd:PRK06225 93 TESLYLVMRAFLSPGDNAVTPDPGYLIIDNFASRFGAE-----VIEVPIYS---EECNYKLTPELVKENMDENTRLIYLI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 181 TPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEwlVYSGNKHLKIATFPgmwERTITIGSAGKTFSVTGWKLGWSIG 260
Cdd:PRK06225 165 DPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYR--DFAREHTLAAEYAP---EHTVTSYSFSKIFGMAGLRIGAVVA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 261 PNHLIKHLQTVQQNTIYTCATPLQEALA----QAFWID-IKRmddpECYFNslpKELeVKrdRMVRLLESVGLkPIVPDG 335
Cdd:PRK06225 240 TPDLIEVVKSIVINDLGTNVIAQEAAIAglkvKDEWIDrIRR----TTFKN---QKL-IK--EAVDEIEGVFL-PVYPSH 308
|
....*....
gi 56713256 336 GYFIIADVS 344
Cdd:PRK06225 309 GNMMVIDIS 317
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
34-317 |
6.82e-16 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 78.58 E-value: 6.82e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 34 LGQGFPDISPPTYVKEELSKIAAidSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNkEILVTVGAYGSLFNTIQ-ALI 112
Cdd:PRK05839 29 LTIGEPQFETPKFIQDALKNNAH--LLNKYPKSAGEESLREAQRGFFKRRFKIELKEN-ELIPTFGTREVLFNFPQfVLF 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 113 DEGDEVILIV-PFYDCYEPMVRMAGATPVFIPLRSkpvygkrwsSSDWT--LDPQELeskfnSKTKAIILNTPHNPLGKV 189
Cdd:PRK05839 106 DKQNPTIAYPnPFYQIYEGAAIASRAKVLLMPLTK---------ENDFTpsLNEKEL-----QEVDLVILNSPNNPTGRT 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 190 YNREELQVIADLCIKYDTLCISDEVY-------------EWLVYSGNKHLKiatfpgmweRTITIGSAGKTFSVTGWKLG 256
Cdd:PRK05839 172 LSLEELIEWVKLALKHDFILINDECYseiyentpppsllEASILVGNESFK---------NVLVINSISKRSSAPGLRSG 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56713256 257 WSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfWIDikrMDDPECYFNSLPKELEVKRD 317
Cdd:PRK05839 243 FIAGDASILKKYKAYRTYLGCASPLPLQKAAAVA-WLD---DEHAEFFRNIYAKNLKLARE 299
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
30-257 |
4.36e-15 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 76.50 E-value: 4.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 30 SVVNLGQGFPDISP---PTYVKEElskiAAIDSL-----NQYTRGFGHPSLVKALS-YLYEKLYQKQidSNKEILVTVGA 100
Cdd:PLN02656 32 RVISLGMGDPTAYScfhTTHVAQE----AVVDALqsnkfNGYAPTVGLPQARRAIAeYLSRDLPYKL--SLDDVFITSGC 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 101 YGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskPVYGkrwsssdWTLDPQELESKFNSKTKAIILN 180
Cdd:PLN02656 106 TQAIDVALSMLARPGANILLPRPGFPIYELCAAFRHLEVRYVDLL--PEKG-------WEVDLDAVEALADQNTVALVII 176
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 56713256 181 TPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFpGMWERTITIGSAGKTFSVTGWKLGW 257
Cdd:PLN02656 177 NPGNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSNPFVPMGVF-GSIVPVLTLGSLSKRWIVPGWRLGW 252
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
90-377 |
5.19e-15 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 76.20 E-value: 5.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 90 SNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMvrmagATPVFIPLRSKPVYGKRwsssDWTLDPQELESK 169
Cdd:PLN00143 96 SPDDVYLTLGCKHAAEIIIKVLARPEANILLPRPGFPDVETY-----AIFHHLEIRHFDLLPEK----GWEVDLDAVEAI 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 170 FNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFpGMWERTITIGSAGKTFS 249
Cdd:PLN00143 167 ADENTIAMVIINPGNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGSKPFVPMGLF-ASIVPVITLGSISKRWM 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 250 VTGWKLGWSI--GPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECY---FNSLPKELEVKRDRMVRLle 324
Cdd:PLN00143 246 IPGWGLGWLVtcDPSGLLQICEIADSIKKALNPAPFPPTFIQAAIPEILEKTTEDFFsktINILRAALAFCYDKLKEI-- 323
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 56713256 325 SVGLKPIVPDGGYFIIADVSLLdpDLSDMKNnepyDYKFVKWMTKHKKLSAIP 377
Cdd:PLN00143 324 PCIMCPQKAEGAFFALVKLNLL--LLEDIED----DMEFCLKLAKEESLIILP 370
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
10-341 |
2.82e-14 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 73.97 E-value: 2.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 10 RIEGLDSNVWIEFT--KLA---ADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLY 84
Cdd:PRK08636 9 KIKRLPKYVFAEVNelKMAarrAGEDIIDFSMGNPDGPTPQHIIDKLCESAQKPKTHGYSVSKGIYKLRLAICNWYKRKY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 85 QKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskpvygkrwSSSDWTLDPQ 164
Cdd:PRK08636 89 NVDLDPETEVVATMGSKEGYVHLVQAITNPGDVAIVPDPAYPIHSQAFILAGGNVHKMPLE---------YNEDFELDED 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 165 E----LESKFNS---KTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWER 237
Cdd:PRK08636 160 QffenLEKALREsspKPKYVVVNFPHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGYKTPSILEVEGAKDV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 238 TITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAfwidikrMDDPECYFNSLPKELEVKRD 317
Cdd:PRK08636 240 AVESYTLSKSYNMAGWRVGFVVGNKKLVGALKKIKSWLDYGMFTPIQVAATIA-------LDGDQSCVEEIRETYRKRRD 312
|
330 340
....*....|....*....|....
gi 56713256 318 RMVRLLESVGLKPIVPDGGYFIIA 341
Cdd:PRK08636 313 VLIESFANAGWELQKPRASMFVWA 336
|
|
| PRK09147 |
PRK09147 |
succinyldiaminopimelate transaminase; Provisional |
22-215 |
5.51e-14 |
|
succinyldiaminopimelate transaminase; Provisional
Pssm-ID: 236393 Cd Length: 396 Bit Score: 72.98 E-value: 5.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 22 FTKLA---------ADPSVVNLGQGFPDISPPTYVKEELskIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQ-IDSN 91
Cdd:PRK09147 13 FEKLRalfagvtppADLPPISLSIGEPKHPTPAFIKDAL--AANLDGLASYPTTAGLPALREAIAAWLERRYGLPaLDPA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 92 KEILVTVGAYGSLFNTIQALIDEGDEVILIV---PFYDCYEPMVRMAGATPVFIPlrSKPvygKRWSSSDWTLDPQELEs 168
Cdd:PRK09147 91 TQVLPVNGSREALFAFAQTVIDRDGPGPLVVcpnPFYQIYEGAALLAGAEPYFLN--CDP---ANNFAPDFDAVPAEVW- 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 56713256 169 kfnSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVY 215
Cdd:PRK09147 165 ---ARTQLLFVCSPGNPTGAVLPLDDWKKLFALSDRYGFVIASDECY 208
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
28-287 |
8.16e-13 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 69.75 E-value: 8.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 28 DPSVVNLGQGFPDISP--PTYVKEELSKIAAIDSL--NQYTRGFG-HPSLVKALSYLYEKLYQKQidSNKEILVTVGAYG 102
Cdd:PLN02187 65 NKTILPLGHGDPSVYPcfRTCIEAEDAVVDVLRSGkgNSYGPGAGiLPARRAVADYMNRDLPHKL--TPEDIFLTAGCNQ 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 103 SLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGatpvfIPLRSKPVYGKRwsssDWTLDPQELESKFNSKTKAIILNTP 182
Cdd:PLN02187 143 GIEIVFESLARPNANILLPRPGFPHYDARAAYSG-----LEVRKFDLLPEK----EWEIDLEGIEAIADENTVAMVVINP 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 183 HNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWErTITIGSAGKTFSVTGWKLGWSI--- 259
Cdd:PLN02187 214 NNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGDNPFVSMGKFASIVP-VLTLAGISKGWVVPGWKIGWIAlnd 292
|
250 260 270
....*....|....*....|....*....|..
gi 56713256 260 --GPNHLIKHLQTVQQNTIYT--CATPLQEAL 287
Cdd:PLN02187 293 peGVFETTKVLQSIKQNLDVTpdPATIIQAAL 324
|
|
| PRK07366 |
PRK07366 |
LL-diaminopimelate aminotransferase; |
8-272 |
1.32e-12 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 180947 Cd Length: 388 Bit Score: 68.94 E-value: 1.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 8 AKRIEGLDSNVWIEFTK-----LAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEK 82
Cdd:PRK07366 4 AQRLQPLQSNVFADMDRakaqaRAAGKELIDLSLGSSDLPAPAHALEAIAQSLHDPSTHGYLLFHGTLDFREAAAQWYEQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 83 LYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSK----PVygkrwsssd 158
Cdd:PRK07366 84 RFGLAVDPETEVLPLIGSQEGTAHLPLAVLNPGDFALLLDPGYPSHAGGVYLAGGQIYPMPLRAEndflPV--------- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 159 WTLDPQELESKfnskTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKiATFPGMWERT 238
Cdd:PRK07366 155 FADIPTEVLAQ----ARLMVLSYPHNPTTAIAPLSFFQEAVAFCQQHDLVLVHDFPYVDLVFDGEVEPP-SILQADPEKS 229
|
250 260 270
....*....|....*....|....*....|....*.
gi 56713256 239 ITIG--SAGKTFSVTGWKLGWSIGPNHLIKHLQTVQ 272
Cdd:PRK07366 230 VSIEffTLSKSYNMGGFRIGFAIGNAQLIQALRQVK 265
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
158-257 |
1.70e-11 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 65.36 E-value: 1.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 158 DWTLDPQELES--KFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATF---- 231
Cdd:PRK06855 154 NWYPDLDDLENkvKYNPSIAGILLINPDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNGKKTVPLSEVigdv 233
|
90 100
....*....|....*....|....*.
gi 56713256 232 PGMWERTITigsagKTFSVTGWKLGW 257
Cdd:PRK06855 234 PGIALKGIS-----KELPWPGSRCGW 254
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
63-224 |
1.08e-10 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 63.06 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 63 YTRGFGHPSLVKALSYLYEKL--YQKQIDSnkeILVTVGAYGSLFNTIQALI-DEGDEVILIVPFYDCYEPMVRMAGATP 139
Cdd:PTZ00377 111 YTDSAGYPFVRKAVAAFIERRdgVPKDPSD---IFLTDGASSGIKLLLQLLIgDPSDGVMIPIPQYPLYSAAITLLGGKQ 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 140 VFIPLRSkpvygkrwsSSDWTLDPQELESKF------NSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDE 213
Cdd:PTZ00377 188 VPYYLDE---------EKGWSLDQEELEEAYeqavrnGITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADE 258
|
170
....*....|.
gi 56713256 214 VYEWLVYSGNK 224
Cdd:PTZ00377 259 VYQENIYDGEK 269
|
|
| PLN03026 |
PLN03026 |
histidinol-phosphate aminotransferase; Provisional |
70-344 |
5.97e-09 |
|
histidinol-phosphate aminotransferase; Provisional
Pssm-ID: 178597 Cd Length: 380 Bit Score: 57.40 E-value: 5.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 70 PSLVKALS-----YLYEKLYQKQI------DSNKE---ILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMA 135
Cdd:PLN03026 68 PEVLEALGnmkfpYVYPDPESRRLraalaeDSGLEsenILVGCGADELIDLLMRCVLDPGDKIIDCPPTFGMYVFDAAVN 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 136 GATPVFIPLrskpvygkrwsSSDWTLD-PQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIkydtLCISDEV 214
Cdd:PLN03026 148 GAEVIKVPR-----------TPDFSLDvPRIVEAVETHKPKLLFLTSPNNPDGSIISDDDLLKILELPI----LVVLDEA 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 215 YewLVYSGNK-HLKIATfpgMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNtiYTCATPLQEALAQAFwi 293
Cdd:PLN03026 213 Y--IEFSTQEsRMKWVK---KYDNLIVLRTFSKRAGLAGLRVGYGAFPLSIIEYLWRAKQP--YNVSVAAEVAACAAL-- 283
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 56713256 294 dikrmDDPEcYFNSLPKELEVKRDRMVRLLESVG-LKPIvPDGGYFIIADVS 344
Cdd:PLN03026 284 -----SNPK-YLEDVKNALVEERERLFGLLKEVPfLEPY-PSDANFILCRVT 328
|
|
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
68-256 |
8.43e-09 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 57.21 E-value: 8.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 68 GHPSLVKALSYLYEKLY--QKQIDSNKeILVTVGAYGS--LFNTIqaLIDEGDEVILIVPFYDCYEPMVRMAGATPVfIP 143
Cdd:PLN02607 96 GLKSFRQAMASFMEQIRggKARFDPDR-IVLTAGATAAneLLTFI--LADPGDALLVPTPYYPGFDRDLRWRTGVKI-VP 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 144 LRSKpvygkrwSSSDWTLDPQELESKF------NSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEW 217
Cdd:PLN02607 172 IHCD-------SSNNFQVTPQALEAAYqeaeaaNIRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSG 244
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 56713256 218 LVYSGNKHLKIAT------FPGMWERTITIGSAGKTFSVTGWKLG 256
Cdd:PLN02607 245 SVFSASEFVSVAEiveargYKGVAERVHIVYSLSKDLGLPGFRVG 289
|
|
| PLN02368 |
PLN02368 |
alanine transaminase |
60-220 |
1.03e-07 |
|
alanine transaminase
Pssm-ID: 177996 [Multi-domain] Cd Length: 407 Bit Score: 53.65 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 60 LNQYTRGFGHPSLVKALSYLYEKlyQKQIDSNKE-ILVTVGAYGSLFNTIQALI-DEGDEVILIVPFYDCYEPMVRMAGA 137
Cdd:PLN02368 100 LGAYSDSRGLPGVRKEVAEFIER--RDGYPSDPElIFLTDGASKGVMQILNAVIrGEKDGVLVPVPQYPLYSATISLLGG 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 138 TPVfiplrskPVYGKRwsSSDWTLDPQELESKFNSK------TKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCIS 211
Cdd:PLN02368 178 TLV-------PYYLEE--SENWGLDVNNLRQSVAQArskgitVRAMVIINPGNPTGQCLSEANLREILKFCYQERLVLLG 248
|
....*....
gi 56713256 212 DEVYEWLVY 220
Cdd:PLN02368 249 DEVYQQNIY 257
|
|
| PRK03321 |
PRK03321 |
putative aminotransferase; Provisional |
96-195 |
1.34e-07 |
|
putative aminotransferase; Provisional
Pssm-ID: 179559 Cd Length: 352 Bit Score: 53.05 E-value: 1.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 96 VTVGAyGS---LFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRskpvygkrwssSDWTLDPQELESKFNS 172
Cdd:PRK03321 77 VAVGC-GSvalCQQLVQATAGPGDEVIFAWRSFEAYPILVQVAGATPVQVPLT-----------PDHTHDLDAMAAAITD 144
|
90 100
....*....|....*....|...
gi 56713256 173 KTKAIILNTPHNPLGKVYNREEL 195
Cdd:PRK03321 145 RTRLIFVCNPNNPTGTVVTPAEL 167
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
92-229 |
2.90e-07 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 52.39 E-value: 2.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 92 KEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVR-MAGATPVFIPLRSKPVYGKRWSSSDWTLDPQElESkf 170
Cdd:PLN02376 120 ERVVMSGGATGANETIMFCLADPGDVFLIPSPYYAAFDRDLRwRTGVEIIPVPCSSSDNFKLTVDAADWAYKKAQ-ES-- 196
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 56713256 171 NSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIA 229
Cdd:PLN02376 197 NKKVKGLILTNPSNPLGTMLDKDTLTNLVRFVTRKNIHLVVDEIYAATVFAGGDFVSVA 255
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
93-243 |
4.39e-07 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 51.86 E-value: 4.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 93 EILVTVGAYGSLFNTIQALI-DEGDEVILIVPFYDCYEPMVRMAGATPVfiplrskPVYGKRwsSSDWTLDPQELESKF- 170
Cdd:PLN02231 193 DIFLTDGASPAVHMMMQLLIrSEKDGILCPIPQYPLYSASIALHGGTLV-------PYYLDE--ATGWGLEISELKKQLe 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 171 NSKTK-----AIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHL----KIATFPGMWERTITI 241
Cdd:PLN02231 264 DARSKgitvrALVVINPGNPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENVYVPDKKFhsfkKVARSMGYGEKDISL 343
|
..
gi 56713256 242 GS 243
Cdd:PLN02231 344 VS 345
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
108-178 |
1.90e-06 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 49.68 E-value: 1.90e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56713256 108 IQAL-IDEGDEVIliVP---FYDCYEPmVRMAGATPVFI---PlrskpvygkrwssSDWTLDPQELESKFNSKTKAII 178
Cdd:COG0399 62 LRALgIGPGDEVI--TPaftFVATANA-ILYVGATPVFVdidP-------------DTYNIDPEALEAAITPRTKAII 123
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
59-260 |
5.90e-06 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 47.80 E-value: 5.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 59 SLNQYTRGFGHPSLVKALSYLYEKLYQKQIDS------NKEILVTVGAYGSLFnTIQALIDEGDEVILIVPFYDCYEPMV 132
Cdd:PRK08354 16 SVNPYPPEWLDEMFERAKEISGRYTYYEWLEEefsklfGEPIVITAGITEALY-LIGILALRDRKVIIPRHTYGEYERVA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 133 RMAGAtpvfiplrsKPVYGKrwsssdwtLDPQELEsKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISD 212
Cdd:PRK08354 95 RFFAA---------RIIKGP--------NDPEKLE-ELVERNSVVFFCNPNNPDGKFYNFKELKPLLDAVEDRNALLILD 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 56713256 213 EVYEWLVYSGNKhlkiatFPGmwERTITIGSAGKTFSVTGWKLGWSIG 260
Cdd:PRK08354 157 EAFIDFVKKPES------PEG--ENIIKLRTFTKSYGLPGIRVGYVKG 196
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
104-212 |
1.67e-05 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 46.46 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 104 LFNTIQALIDEGDEVILIvpfYDCYEPMVRM-------AGATPVFIPlrskpvygkrwsssdwTLDPQELESKFNSKTKA 176
Cdd:pfam01053 75 ITAAILALLKAGDHIVAT---DDLYGGTYRLfnkvlprFGIEVTFVD----------------TSDPEDLEAAIKPNTKA 135
|
90 100 110
....*....|....*....|....*....|....*.
gi 56713256 177 IILNTPHNPLGKVYnreELQVIADLCIKYDTLCISD 212
Cdd:pfam01053 136 VYLETPTNPLLKVV---DIEAIAKLAKKHGILVVVD 168
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
112-212 |
1.93e-05 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 46.38 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 112 IDEGDEVIliVPfydcyePM--------VRMAGATPVFI---PlrskpvygkrwssSDWTLDPQELESKFNSKTKAIIln 180
Cdd:cd00616 55 IGPGDEVI--VP------SFtfvatanaILLLGATPVFVdidP-------------DTYNIDPELIEAAITPRTKAII-- 111
|
90 100 110
....*....|....*....|....*....|..
gi 56713256 181 tPHNPLGKVYNREELQVIADlciKYDTLCISD 212
Cdd:cd00616 112 -PVHLYGNPADMDAIMAIAK---RHGLPVIED 139
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
104-256 |
7.03e-05 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 44.86 E-value: 7.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 104 LFNTIQA--LIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPvygkrwsSSDWTLDPQELESKFNSKTKAIILNT 181
Cdd:PRK09275 177 IFDSLKEngLLKAGDKIALMTPIFTPYLEIPELPRYDLEVVHINADE-------ENEWQYPDSELEKLRDPSIKALFLVN 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 182 PHNPLGKVYNREELQVIADLCIKY--DTLCISDEVYewlvysgnkhlkiATF-PGMweRTI-------TIG--SAGKTFS 249
Cdd:PRK09275 250 PSNPPSVAMSDESLEKIADIVNEKrpDLMIITDDVY-------------GTFvDDF--RSLfavlpynTILvySFSKYFG 314
|
....*..
gi 56713256 250 VTGWKLG 256
Cdd:PRK09275 315 ATGWRLG 321
|
|
| PLN02450 |
PLN02450 |
1-aminocyclopropane-1-carboxylate synthase |
68-221 |
8.90e-05 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178069 [Multi-domain] Cd Length: 468 Bit Score: 44.74 E-value: 8.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 68 GHPSLVKALSYLYEKL--YQKQIDSNKeILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVR-MAGATPVfiPL 144
Cdd:PLN02450 87 GLPAFKNALAEFMSEIrgNKVTFDPNK-LVLTAGATSANETLMFCLAEPGDAFLLPTPYYPGFDRDLKwRTGVEIV--PI 163
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56713256 145 RSKPVYGKRWSSSdwTLDPQELES-KFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYS 221
Cdd:PLN02450 164 HCSSSNGFQITES--ALEEAYQQAqKLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFD 239
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
90-215 |
1.02e-04 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 42.75 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 90 SNKEILVTVGAYGSLFNTIQALIDEGDEVILIVP-FYDCYEPMVRMAGATPVFIPlrsKPVYGKRwsssdwTLDPQELES 168
Cdd:cd01494 16 GNDKAVFVPSGTGANEAALLALLGPGDEVIVDANgHGSRYWVAAELAGAKPVPVP---VDDAGYG------GLDVAILEE 86
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 56713256 169 KFNSK-TKAIILNTPHNPLGKVYNREElqvIADLCIKYDTLCISDEVY 215
Cdd:cd01494 87 LKAKPnVALIVITPNTTSGGVLVPLKE---IRKIAKEYGILLLVDAAS 131
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
146-212 |
2.06e-04 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 43.15 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 146 SKPVYG----------KRWSSS---DWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNreeLQVIADLCIKYDTLCISD 212
Cdd:PRK08247 96 SSDLYGgtyrlfeehwKKWNVRfvyVNTASLKAIEQAITPNTKAIFIETPTNPLMQETD---IAAIAKIAKKHGLLLIVD 172
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
109-212 |
3.81e-04 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 42.27 E-value: 3.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 109 QAL-IDEGDEVILiVPF-YDCYEPMVRMAGATPVFIPLrsKPVygkrwsssDWTLDPQELESKFNSKTKAIIlntPHNPL 186
Cdd:pfam01041 57 RALgVGPGDEVIT-PSFtFVATANAALRLGAKPVFVDI--DPD--------TYNIDPEAIEAAITPRTKAII---PVHLY 122
|
90 100
....*....|....*....|....*.
gi 56713256 187 GKVYnreELQVIADLCIKYDTLCISD 212
Cdd:pfam01041 123 GQPA---DMDAIRAIAARHGLPVIED 145
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
40-202 |
9.63e-03 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 37.95 E-value: 9.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 40 DISPP-----TYVKEELSKIAAIDSL----NQYTRGfGHPSlVKALsylyeklyQKQIdsnKEILVTVGAY------GSL 104
Cdd:cd00614 2 AVAPPiyqtsTFVFPSPAEAADLFALreggYIYSRI-GNPT-VDAL--------EKKL---AALEGGEAALafssgmAAI 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56713256 105 FNTIQALIDEGDEViliVPFYDCYepmvrmaGATPVFIPlRSKPVYGKRWSSSDwTLDPQELESKFNSKTKAIILNTPHN 184
Cdd:cd00614 69 STVLLALLKAGDHV---VASDDLY-------GGTYRLFE-RLLPKLGIEVTFVD-PDDPEALEAAIKPETKLVYVESPTN 136
|
170
....*....|....*...
gi 56713256 185 PLGKVYNREElqvIADLC 202
Cdd:cd00614 137 PTLKVVDIEA---IAELA 151
|
|
| |
