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Conserved domains on  [gi|58197562|ref|NP_001010875|]
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kidney mitochondrial carrier protein 1 isoform 1 [Homo sapiens]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 9-289 4.25e-27

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 107.16  E-value: 4.25e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562    9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEI-RYRGMLHALVRIGREEGLKALYSGIAPAMLRQASYGTIKI 87
Cdd:PTZ00169  11 FLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562   88 GTYQSLKRLFiERPEDET-----LPINVICGILSGVISSTIANPTDVLKIRMQA----QSNTIQGGMIGNFMNIYQQEGT 158
Cdd:PTZ00169  91 AFKDYFKNMF-PKYNQKTdfwkfFGVNILSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCLMKISKQTGF 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562  159 RGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGaLASNPVDVVRTRMMNQRVLRDGR 238
Cdd:PTZ00169 170 LSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYKWAVAQTVTILAG-LISYPFDTVRRRMMMMSGRKAKS 248

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 58197562  239 CSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRlGPWNIIFFVTYEQLKKL 289
Cdd:PTZ00169 249 EIQYTGTLDCWKKILKNEGLGGFFKGAWANVLR-GAGGALVLVFYDELQKL 298
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 9-289 4.25e-27

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 107.16  E-value: 4.25e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562    9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEI-RYRGMLHALVRIGREEGLKALYSGIAPAMLRQASYGTIKI 87
Cdd:PTZ00169  11 FLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562   88 GTYQSLKRLFiERPEDET-----LPINVICGILSGVISSTIANPTDVLKIRMQA----QSNTIQGGMIGNFMNIYQQEGT 158
Cdd:PTZ00169  91 AFKDYFKNMF-PKYNQKTdfwkfFGVNILSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCLMKISKQTGF 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562  159 RGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGaLASNPVDVVRTRMMNQRVLRDGR 238
Cdd:PTZ00169 170 LSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYKWAVAQTVTILAG-LISYPFDTVRRRMMMMSGRKAKS 248

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 58197562  239 CSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRlGPWNIIFFVTYEQLKKL 289
Cdd:PTZ00169 249 EIQYTGTLDCWKKILKNEGLGGFFKGAWANVLR-GAGGALVLVFYDELQKL 298
Mito_carr pfam00153
Mitochondrial carrier protein;
199-289 4.50e-27

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 101.19  E-value: 4.50e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562   199 TVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRcsgYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNII 278
Cdd:pfam00153   4 SFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|.
gi 58197562   279 FFVTYEQLKKL 289
Cdd:pfam00153  81 YFGTYETLKRL 91
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 9-289 4.25e-27

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 107.16  E-value: 4.25e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562    9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEI-RYRGMLHALVRIGREEGLKALYSGIAPAMLRQASYGTIKI 87
Cdd:PTZ00169  11 FLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562   88 GTYQSLKRLFiERPEDET-----LPINVICGILSGVISSTIANPTDVLKIRMQA----QSNTIQGGMIGNFMNIYQQEGT 158
Cdd:PTZ00169  91 AFKDYFKNMF-PKYNQKTdfwkfFGVNILSGGLAGASSLLIVYPLDFARTRLASdigkGGDREFTGLFDCLMKISKQTGF 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562  159 RGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGaLASNPVDVVRTRMMNQRVLRDGR 238
Cdd:PTZ00169 170 LSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNILYKWAVAQTVTILAG-LISYPFDTVRRRMMMMSGRKAKS 248

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 58197562  239 CSGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRlGPWNIIFFVTYEQLKKL 289
Cdd:PTZ00169 249 EIQYTGTLDCWKKILKNEGLGGFFKGAWANVLR-GAGGALVLVFYDELQKL 298
Mito_carr pfam00153
Mitochondrial carrier protein;
199-289 4.50e-27

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 101.19  E-value: 4.50e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562   199 TVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRcsgYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNII 278
Cdd:pfam00153   4 SFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|.
gi 58197562   279 FFVTYEQLKKL 289
Cdd:pfam00153  81 YFGTYETLKRL 91
Mito_carr pfam00153
Mitochondrial carrier protein;
5-100 2.05e-22

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 88.87  E-value: 2.05e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562     5 NWKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTndakfKEIRYRGMLHALVRIGREEGLKALYSGIAPAMLRQASYGT 84
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGS-----GKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAA 79

                          90
                  ....*....|....*.
gi 58197562    85 IKIGTYQSLKRLFIER 100
Cdd:pfam00153  80 IYFGTYETLKRLLLKK 95
Mito_carr pfam00153
Mitochondrial carrier protein;
102-191 1.74e-21

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 86.56  E-value: 1.74e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562   102 EDETLPINVICGILSGVISSTIANPTDVLKIRMQAQS---NTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGV 178
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGgsgKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|...
gi 58197562   179 ELPVYDITKKHLI 191
Cdd:pfam00153  81 YFGTYETLKRLLL 93
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 5-280 1.01e-06

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 48.77  E-value: 1.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562    5 NWKPFVYGGLASITAECGTFPIDLTKTRLQIQgqtNDAKFKEIryrgmlhalvrigreeglKALYSGIAPAMLrqasyGT 84
Cdd:PTZ00168   3 HFHNLVTGALSGVIVDAVLYPIDSIKTNIQAK---KSFSFSDI------------------KKLYSGILPTLV-----GT 56

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562   85 IKIGT-----YQSLKRLFIERPED-ETLPINVICGILSGVISSTIANPTDVLKIRMQAQSNTiqgGMIGNFMNIYQQEGT 158
Cdd:PTZ00168  57 VPASAffycfYELSKKLLTEYRENiSKTNLYLISTSIAEITACIVRLPFEIVKQNMQVSGNI---SVLKTIYEITQREGL 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58197562  159 rglwkgVSLTAQRAAIVVGVELP-------VYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALA---SNPVDVVRTRM 228
Cdd:PTZ00168 134 ------PSFLGKSYFVMIVREIPfdciqyfLWETLKEKAKKDFGKFSKKYPSITSAICGGLAGGIAgflTTPVDVIKSRQ 207

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 58197562  229 MNQrvlrdGRcsGYTGTLDCLLQtwknEGFFALYKG--FWPNWLRLGpwNIIFF 280
Cdd:PTZ00168 208 IIY-----GK--SYIETVTEIAE----EGYLTFYKGccFRSSYLFFG--GLIFF 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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