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Conserved domains on  [gi|62955775|ref|NP_001017902|]
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tRNA N(3)-methylcytidine methyltransferase METTL2 [Danio rerio]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 10614797)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

CATH:  2.20.25.110
EC:  2.1.-.-|2.1.1.-
Gene Ontology:  GO:0032259|GO:0008757|GO:0008168|GO:1904047
PubMed:  12504684|12826405

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 161-263 1.09e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


:

Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 79.92  E-value: 1.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   161 ILEVGCGVGNTVFPILKTnndPGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVHDMSDesgeYPMPDHSLDVIVLIFVL 240
Cdd:pfam13649   1 VLDLGCGTGRLTLALARR---GGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAED----LPFPDGSFDLVVSSGVL 73

                          90       100
                  ....*....|....*....|...
gi 62955775   241 SALHPEKMQKSINRLGRLLKPGG 263
Cdd:pfam13649  74 HHLPDPDLEAALREIARVLKPGG 96
 
Name Accession Description Interval E-value
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 161-263 1.09e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 79.92  E-value: 1.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   161 ILEVGCGVGNTVFPILKTnndPGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVHDMSDesgeYPMPDHSLDVIVLIFVL 240
Cdd:pfam13649   1 VLDLGCGTGRLTLALARR---GGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAED----LPFPDGSFDLVVSSGVL 73

                          90       100
                  ....*....|....*....|...
gi 62955775   241 SALHPEKMQKSINRLGRLLKPGG 263
Cdd:pfam13649  74 HHLPDPDLEAALREIARVLKPGG 96
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 160-279 4.59e-15

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 71.56  E-value: 4.59e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKTnndpGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVHDMSDesgeYPMPDHSLDVIVLIFV 239
Cdd:COG2226  25 RVLDLGCGTGRLALALAER----GARVTGVDISPEMLELARERAAEAGLNVEFVVGDAED----LPFPDGSFDLVISSFV 96

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 62955775 240 LSalHPEKMQKSINRLGRLLKPGGVLLLRDYGRYDMAQLR 279
Cdd:COG2226  97 LH--HLPDPERALAEIARVLKPGGRLVVVDFSPPDLAELE 134
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 160-267 2.01e-11

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 60.14  E-value: 2.01e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKtnnDPGLFVYCCDFSSTAVD-LVKSNPEYDPSRCHAFVHDMSDESgeyPMPDHSLDVIVLIF 238
Cdd:cd02440   1 RVLDLGCGTGALALALAS---GPGARVTGVDISPVALElARKAAAALLADNVEVLKGDAEELP---PEADESFDVIISDP 74

                        90       100
                ....*....|....*....|....*....
gi 62955775 239 VLSALHPEkMQKSINRLGRLLKPGGVLLL 267
Cdd:cd02440  75 PLHHLVED-LARFLEEARRLLKPGGVLVL 102
PRK08317 PRK08317
hypothetical protein; Provisional
 160-269 2.80e-05

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 44.93  E-value: 2.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775  160 RILEVGCGVGNTVFPILKTNNDPGLfVYCCDFSSTAVDLVKSNPEYDPSRChAFVHDMSDESgeyPMPDHSLDVIVLIFV 239
Cdd:PRK08317  22 RVLDVGCGPGNDARELARRVGPEGR-VVGIDRSEAMLALAKERAAGLGPNV-EFVRGDADGL---PFPDGSFDAVRSDRV 96

                         90       100       110
                 ....*....|....*....|....*....|
gi 62955775  240 LSalHPEKMQKSINRLGRLLKPGGVLLLRD 269
Cdd:PRK08317  97 LQ--HLEDPARALAEIARVLRPGGRVVVLD 124
 
Name Accession Description Interval E-value
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 161-263 1.09e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 79.92  E-value: 1.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   161 ILEVGCGVGNTVFPILKTnndPGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVHDMSDesgeYPMPDHSLDVIVLIFVL 240
Cdd:pfam13649   1 VLDLGCGTGRLTLALARR---GGARVTGVDLSPEMLERARERAAEAGLNVEFVQGDAED----LPFPDGSFDLVVSSGVL 73

                          90       100
                  ....*....|....*....|...
gi 62955775   241 SALHPEKMQKSINRLGRLLKPGG 263
Cdd:pfam13649  74 HHLPDPDLEAALREIARVLKPGG 96
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 162-265 4.49e-17

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 75.48  E-value: 4.49e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   162 LEVGCGVGNTVFPILKTNndPGLFVYCCDFSSTAVDL----VKSNPEYDPSRCHAFVHDMSDESGEypmpdhSLDVIVLI 237
Cdd:pfam08242   1 LEIGCGTGTLLRALLEAL--PGLEYTGLDISPAALEAarerLAALGLLNAVRVELFQLDLGELDPG------SFDVVVAS 72

                          90       100
                  ....*....|....*....|....*...
gi 62955775   238 FVLSALhpEKMQKSINRLGRLLKPGGVL 265
Cdd:pfam08242  73 NVLHHL--ADPRAVLRNIRRLLKPGGVL 98
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 160-279 4.59e-15

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 71.56  E-value: 4.59e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKTnndpGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVHDMSDesgeYPMPDHSLDVIVLIFV 239
Cdd:COG2226  25 RVLDLGCGTGRLALALAER----GARVTGVDISPEMLELARERAAEAGLNVEFVVGDAED----LPFPDGSFDLVISSFV 96

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 62955775 240 LSalHPEKMQKSINRLGRLLKPGGVLLLRDYGRYDMAQLR 279
Cdd:COG2226  97 LH--HLPDPERALAEIARVLKPGGRLVVVDFSPPDLAELE 134
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 160-267 4.56e-14

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 69.95  E-value: 4.56e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKTNNDPglfVYCCDFSSTAVDLVKSN-PEYDPSRCHAFVHDMSDEsgeYPMPDHSLDVIVLIF 238
Cdd:COG0500  29 RVLDLGCGTGRNLLALAARFGGR---VIGIDLSPEAIALARARaAKAGLGNVEFLVADLAEL---DPLPAESFDLVVAFG 102

                        90       100
                ....*....|....*....|....*....
gi 62955775 239 VLSALHPEKMQKSINRLGRLLKPGGVLLL 267
Cdd:COG0500 103 VLHHLPPEEREALLRELARALKPGGVLLL 131
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
160-317 7.76e-12

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 63.09  E-value: 7.76e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKTnndpGLFVYCCDFSSTAVDLVKSNPEYDpsrcHAFVHDMSDesgeYPMPDHSLDVIVLIFV 239
Cdd:COG4976  49 RVLDLGCGTGLLGEALRPR----GYRLTGVDLSEEMLAKAREKGVYD----RLLVADLAD----LAEPDGRFDLIVAADV 116

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 62955775 240 LSalHPEKMQKSINRLGRLLKPGGVLLlrdygrydmaqlrfkkgrclsenFYV-RGDGTLVYFFTQDELHDLFSSAGLE 317
Cdd:COG4976 117 LT--YLGDLAAVFAGVARALKPGGLFI-----------------------FSVeDADGSGRYAHSLDYVRDLLAAAGFE 170
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 160-270 1.16e-11

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 61.19  E-value: 1.16e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKTnndpGLFVYCCDFSSTAVDLVKSNpeYDPSRCHAFVHDMSDesgeYPMPDHSLDVIVLIFV 239
Cdd:COG2227  27 RVLDVGCGTGRLALALARR----GADVTGVDISPEALEIARER--AAELNVDFVQGDLED----LPLEDGSFDLVICSEV 96

                        90       100       110
                ....*....|....*....|....*....|.
gi 62955775 240 LSalHPEKMQKSINRLGRLLKPGGVLLLRDY 270
Cdd:COG2227  97 LE--HLPDPAALLRELARLLKPGGLLLLSTP 125
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 160-267 2.01e-11

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 60.14  E-value: 2.01e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKtnnDPGLFVYCCDFSSTAVD-LVKSNPEYDPSRCHAFVHDMSDESgeyPMPDHSLDVIVLIF 238
Cdd:cd02440   1 RVLDLGCGTGALALALAS---GPGARVTGVDISPVALElARKAAAALLADNVEVLKGDAEELP---PEADESFDVIISDP 74

                        90       100
                ....*....|....*....|....*....
gi 62955775 239 VLSALHPEkMQKSINRLGRLLKPGGVLLL 267
Cdd:cd02440  75 PLHHLVED-LARFLEEARRLLKPGGVLVL 102
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 152-320 6.07e-11

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 60.13  E-value: 6.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   152 FPGASASYRILEVGCGVGNtVFPILKTNNdpglfvyccdFSSTAVDLvksNPEYDPSRCHAFVHDMSDESGEYPMPDHSl 231
Cdd:pfam13489  17 LPKLPSPGRVLDFGCGTGI-FLRLLRAQG----------FSVTGVDP---SPIAIERALLNVRFDQFDEQEAAVPAGKF- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   232 DVIVLIFVLSALH--PEKMQksinRLGRLLKPGGVLLLRDYGRYDMAQLRFKKGRCLSENfyvrgdGTLVYFFTQDELHD 309
Cdd:pfam13489  82 DVIVAREVLEHVPdpPALLR----QIAALLKPGGLLLLSTPLASDEADRLLLEWPYLRPR------NGHISLFSARSLKR 151

                         170
                  ....*....|.
gi 62955775   310 LFSSAGLEKLQ 320
Cdd:pfam13489 152 LLEEAGFEVVS 162
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 162-267 1.15e-10

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 57.67  E-value: 1.15e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   162 LEVGCGVGNTVFPILKTnndpGLFVYCCDFSSTAVDLVKSNpeYDPSRCHAFVHDMSDesgeYPMPDHSLDVIVLIFVLs 241
Cdd:pfam08241   1 LDVGCGTGLLTELLARL----GARVTGVDISPEMLELAREK--APREGLTFVVGDAED----LPFPDNSFDLVLSSEVL- 69

                          90       100
                  ....*....|....*....|....*.
gi 62955775   242 aLHPEKMQKSINRLGRLLKPGGVLLL 267
Cdd:pfam08241  70 -HHVEDPERALREIARVLKPGGILII 94
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
160-267 1.12e-09

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 54.83  E-value: 1.12e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKTNndPGLFVYCCDFSSTAVDLVKSNPeydpSRCHAFVHDMSDesgeyPMPDHSLDVIVLIFV 239
Cdd:COG4106   4 RVLDLGCGTGRLTALLAERF--PGARVTGVDLSPEMLARARARL----PNVRFVVADLRD-----LDPPEPFDLVVSNAA 72

                        90       100
                ....*....|....*....|....*...
gi 62955775 240 LSalHPEKMQKSINRLGRLLKPGGVLLL 267
Cdd:COG4106  73 LH--WLPDHAALLARLAAALAPGGVLAV 98
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 160-269 7.79e-08

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 51.08  E-value: 7.79e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGNTVFPILKTNndpGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVH--DMSDESgeypmPDHSLDVIVLI 237
Cdd:COG2230  54 RVLDIGCGWGGLALYLARRY---GVRVTGVTLSPEQLEYARERAAEAGLADRVEVRlaDYRDLP-----ADGQFDAIVSI 125

                        90       100       110
                ....*....|....*....|....*....|..
gi 62955775 238 FVLSALHPEKMQKSINRLGRLLKPGGVLLLRD 269
Cdd:COG2230 126 GMFEHVGPENYPAYFAKVARLLKPGGRLLLHT 157
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 156-315 6.62e-06

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 45.49  E-value: 6.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   156 SASYRILEVGCGVGNTVFPILKTNNDPGlFVYCCDFSSTAVDLVKSNPE-YDPSRCHAFVHDMSDESGEYPmpDHSLDVI 234
Cdd:pfam13847   2 DKGMRVLDLGCGTGHLSFELAEELGPNA-EVVGIDISEEAIEKARENAQkLGFDNVEFEQGDIEELPELLE--DDKFDVV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775   235 VLIFVLSALhPEKmQKSINRLGRLLKPGGVLLLRDYGRydMAQLRfkkGRCLSENFYVRGDGTLVYffTQDELHDLFSSA 314
Cdd:pfam13847  79 ISNCVLNHI-PDP-DKVLQEILRVLKPGGRLIISDPDS--LAELP---AHVKEDSTYYAGCVGGAI--LKKKLYELLEEA 149


                  .
gi 62955775   315 G 315
Cdd:pfam13847 150 G 150
PRK08317 PRK08317
hypothetical protein; Provisional
 160-269 2.80e-05

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 44.93  E-value: 2.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775  160 RILEVGCGVGNTVFPILKTNNDPGLfVYCCDFSSTAVDLVKSNPEYDPSRChAFVHDMSDESgeyPMPDHSLDVIVLIFV 239
Cdd:PRK08317  22 RVLDVGCGPGNDARELARRVGPEGR-VVGIDRSEAMLALAKERAAGLGPNV-EFVRGDADGL---PFPDGSFDAVRSDRV 96

                         90       100       110
                 ....*....|....*....|....*....|
gi 62955775  240 LSalHPEKMQKSINRLGRLLKPGGVLLLRD 269
Cdd:PRK08317  97 LQ--HLEDPARALAEIARVLRPGGRVVVLD 124
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 160-267 1.95e-04

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 41.71  E-value: 1.95e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62955775 160 RILEVGCGVGntvfPI---LKTNNdPGLFVYCCDFSSTAVDLVKSN-PEYDPSRCHAFVHDMSDesgeyPMPDHSLDVIV 235
Cdd:COG2813  52 RVLDLGCGYG----VIglaLAKRN-PEARVTLVDVNARAVELARANaAANGLENVEVLWSDGLS-----GVPDGSFDLIL 121

                        90       100       110
                ....*....|....*....|....*....|....*
gi 62955775 236 L---IFVLSALHPEKMQKSINRLGRLLKPGGVLLL 267
Cdd:COG2813 122 SnppFHAGRAVDKEVAHALIADAARHLRPGGELWL 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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