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Conserved domains on  [gi|725503307|ref|NP_001032756|]
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cytoskeleton-associated protein 5 [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
514-669 1.21e-04

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK14951:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 618  Bit Score: 47.02  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307  514 PAAKAS---PPVEAPAKTSGPPKKSAPAKAAGPPKKGKPAAAPSAKSKKAPetkEIIETELSPEVCEEKAAAVLPASCMQ 590
Cdd:PRK14951  375 PAEKKTparPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAP---VAAPAAAAPAAAPAAAPAAVALAPAP 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307  591 LLDSANWKERLASMEEFQKAVEQMDKSEMPCQALVKMLAKKPG--WKETnfqVMQM--KLSIVGLVAQKGQfskTSALVV 666
Cdd:PRK14951  452 PAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGdvWHAT---VQQLaaAEAITALARELAL---QSELVA 525


                  ...
gi 725503307  667 LDG 669
Cdd:PRK14951  526 RDG 528
 
Name Accession Description Interval E-value
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 514-669 1.21e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.02  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307  514 PAAKAS---PPVEAPAKTSGPPKKSAPAKAAGPPKKGKPAAAPSAKSKKAPetkEIIETELSPEVCEEKAAAVLPASCMQ 590
Cdd:PRK14951  375 PAEKKTparPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAP---VAAPAAAAPAAAPAAAPAAVALAPAP 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307  591 LLDSANWKERLASMEEFQKAVEQMDKSEMPCQALVKMLAKKPG--WKETnfqVMQM--KLSIVGLVAQKGQfskTSALVV 666
Cdd:PRK14951  452 PAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGdvWHAT---VQQLaaAEAITALARELAL---QSELVA 525


                  ...
gi 725503307  667 LDG 669
Cdd:PRK14951  526 RDG 528
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
514-590 1.07e-03

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 43.91  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307   514 PAAKASPPVEAPAKTSGPPKKSAPAKaaGPPKKGKPAAAPS-------AKSKKAPETKEIIETELSPEVCEEKAAAVLPA 586
Cdd:pfam03546   39 PAAKTPLQAKPSGKTPQVRAASAPAK--ESPRKGAPPVPPGktgpaaaQAQAGKPEEDSESSSEESDSDGETPAAATLTT 116


                   ....
gi 725503307   587 SCMQ 590
Cdd:pfam03546  117 SPAQ 120
 
Name Accession Description Interval E-value
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 514-669 1.21e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.02  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307  514 PAAKAS---PPVEAPAKTSGPPKKSAPAKAAGPPKKGKPAAAPSAKSKKAPetkEIIETELSPEVCEEKAAAVLPASCMQ 590
Cdd:PRK14951  375 PAEKKTparPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAP---VAAPAAAAPAAAPAAAPAAVALAPAP 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307  591 LLDSANWKERLASMEEFQKAVEQMDKSEMPCQALVKMLAKKPG--WKETnfqVMQM--KLSIVGLVAQKGQfskTSALVV 666
Cdd:PRK14951  452 PAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGdvWHAT---VQQLaaAEAITALARELAL---QSELVA 525


                  ...
gi 725503307  667 LDG 669
Cdd:PRK14951  526 RDG 528
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 514-573 3.17e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 46.04  E-value: 3.17e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307  514 PAAKASPPVEAPAKTSGPPKKSAPAKAAGPPKKGKPAAAPSAKSKKAPETKEIIETELSP 573
Cdd:PRK12270   60 AAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEVTP 119
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 514-565 7.65e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 44.17  E-value: 7.65e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 725503307  514 PAAKASPPVEA---PAKTSGPPKKSA--PAKAAGPPKKgkpAAAPSAKSKKAPETKE 565
Cdd:PTZ00436  299 PAKAAAAPAKAaaaPAKAAAPPAKAAapPAKAATPPAK---AAAPPAKAAAAPVGKK 352
Treacle pfam03546
Treacher Collins syndrome protein Treacle;
514-590 1.07e-03

Treacher Collins syndrome protein Treacle;


Pssm-ID: 460967 [Multi-domain]  Cd Length: 531  Bit Score: 43.91  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 725503307   514 PAAKASPPVEAPAKTSGPPKKSAPAKaaGPPKKGKPAAAPS-------AKSKKAPETKEIIETELSPEVCEEKAAAVLPA 586
Cdd:pfam03546   39 PAAKTPLQAKPSGKTPQVRAASAPAK--ESPRKGAPPVPPGktgpaaaQAQAGKPEEDSESSSEESDSDGETPAAATLTT 116


                   ....
gi 725503307   587 SCMQ 590
Cdd:pfam03546  117 SPAQ 120
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 514-561 1.16e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.40  E-value: 1.16e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 725503307  514 PAAKASPPVEA---PAKTSGPPKKSA--PAKAAGPPKKgkpAAAPSAKSKKAP 561
Cdd:PTZ00436  250 PAKAAAPPAKAaapPAKAAAPPAKAAapPAKAAAPPAK---AAAPPAKAAAAP 299
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 514-561 1.44e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.01  E-value: 1.44e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 725503307  514 PAAKASPPVEA---PAKTSGPPKK--SAPAKAAGPPKKgkpAAAPSAKSKKAP 561
Cdd:PTZ00436  285 PAKAAAPPAKAaaaPAKAAAAPAKaaAAPAKAAAPPAK---AAAPPAKAATPP 334
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 514-561 2.09e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 42.63  E-value: 2.09e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 725503307  514 PAAKASPPVEA---PAKTSGPPKKSA--PAKAAGPPKKgkpAAAPSAKSKKAP 561
Cdd:PTZ00436  229 PAKAAAPPAKAaaaPAKAAAAPAKAAapPAKAAAPPAK---AAAPPAKAAAPP 278
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 514-561 2.51e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 42.24  E-value: 2.51e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 725503307  514 PAAKASPPVEA---PAKTSGPPKKSA--PAKAAGPPKKgkpAAAPSAKSKKAP 561
Cdd:PTZ00436  236 PAKAAAAPAKAaaaPAKAAAPPAKAAapPAKAAAPPAK---AAAPPAKAAAPP 285
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 514-561 2.60e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 42.24  E-value: 2.60e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 725503307  514 PAAKASPPVEA---PAKTSGPPKKSA--PAKAAGPPKKgkpAAAPSAKSKKAP 561
Cdd:PTZ00436  243 PAKAAAAPAKAaapPAKAAAPPAKAAapPAKAAAPPAK---AAAPPAKAAAPP 292
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 514-575 2.74e-03

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 42.96  E-value: 2.74e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 725503307  514 PAAKASPPVEAPAKTSGPPKKSAPAKAAGPPKKGKPAAAPSAKSKKAPETKEIIETELSPEV 575
Cdd:PRK12270   56 SAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 514-561 2.79e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 42.24  E-value: 2.79e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 725503307  514 PAAKASPPVEA---PAKTSGPPKKSA--PAKAAGPPKKGKPA----AAPSAKSKKAP 561
Cdd:PTZ00436  257 PAKAAAPPAKAaapPAKAAAPPAKAAapPAKAAAPPAKAAAApakaAAAPAKAAAAP 313
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 513-561 3.14e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 42.24  E-value: 3.14e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 725503307  513 RPAAKASPPVEA---PAKTSGPPKKSA--PAKAAGPPKKgkpAAAPSAKSKKAP 561
Cdd:PTZ00436  214 KKSAKAAAPAKAaaaPAKAAAPPAKAAaaPAKAAAAPAK---AAAPPAKAAAPP 264
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
 514-561 4.60e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.47  E-value: 4.60e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 725503307  514 PAAKASPPVEA---PAKTSGPPKK--SAPAKAAGPPKKGKPA----AAPSAKSKKAP 561
Cdd:PTZ00436  271 PAKAAAPPAKAaapPAKAAAPPAKaaAAPAKAAAAPAKAAAApakaAAPPAKAAAPP 327
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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