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solute carrier family 12 member 6 isoform d [Homo sapiens]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
100-1141
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1356.69
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 100 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKTPQM G T 178
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 179 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 258
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 259 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIFHSD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 338
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLLREN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 339 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhidvcsktkeinnmtvpsklwgffcnssqffnatcdey F VH N 418
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 419 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgslnheyvlvditts F TL L V GIFFPSVTGI M AG S N R SG 498
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 499 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 557
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 558 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 636
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 637 L S M FFL MC Y LFV N LA C ALQT LLR T P N WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 716
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 717 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 796
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 797 EA L AAE QT I KHLM E AE KVK G F CQL VVA AK LREG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 876
Cdd:TIGR00930 621 EA Q AAE AK I QTWL E KN KVK A F YAV VVA DD LREG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 877 AHLA LL V AK N ISFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 918
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 919 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 998
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 999 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkaksmegf QD L lnmrpd QSNVR RMHTA 1078
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 110224456 1079 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1141
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
100-1141
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1356.69
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 100 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKTPQM G T 178
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 179 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 258
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 259 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIFHSD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 338
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLLREN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 339 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhidvcsktkeinnmtvpsklwgffcnssqffnatcdey F VH N 418
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 419 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgslnheyvlvditts F TL L V GIFFPSVTGI M AG S N R SG 498
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 499 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 557
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 558 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 636
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 637 L S M FFL MC Y LFV N LA C ALQT LLR T P N WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 716
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 717 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 796
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 797 EA L AAE QT I KHLM E AE KVK G F CQL VVA AK LREG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 876
Cdd:TIGR00930 621 EA Q AAE AK I QTWL E KN KVK A F YAV VVA DD LREG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 877 AHLA LL V AK N ISFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 918
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 919 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 998
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 999 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkaksmegf QD L lnmrpd QSNVR RMHTA 1078
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 110224456 1079 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1141
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
181-751
1.63e-48
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 180.21
E-value: 1.63e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 181 G V YLPC L QNIF G VI LF LRLTW V V G T AG VLQ A FAIV LI CCCCTM L TAI S MSA I A TNG V V p A GG S Y FMI SR A LGP EF G G A V G 260
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGS V L G Q AG PAG A LLGY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 261 L -- CFYLG T TF A AA myi L G A IE I FLVYIVPRAA I fhsddalkesaaml NNMR V Y G TA FLVL MVLVVFI GV RYVNKFASL F 338
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS I LIQFWELVPD I -------------- PYLW V W G AV FLVL LTIINLV GV KWYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 339 LACV I VS I LAIYAGA I -- K S SFA P PHFPV cmlgnrtlssrhidvcsktkeinnmtvpsklwgffcnssqffnatcd EYFV 416
Cdd:pfam00324 143 ALIK I IA I IGFIIVG I il L S GGN P NDGAI ----------------------------------------------- FRYL 175
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 417 HN N VTSIQGI PG LAS G I I tenlwsnylpkgeiiekpsakssdvlgslnhe Y V L V dittsftllvg I F F PSV TGI MAGSNR 496
Cdd:pfam00324 176 GD N GGKNNFP PG FGK G F I -------------------------------- S V F V ----------- I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 497 S G DL K DAQ KSIP IGTILA I LTTSFV Y LSNVVLF G ACIEG -- VV L RDKFGD A VKGNLVVGTLSWP S -- PWV I VIGSFFSTC 572
Cdd:pfam00324 213 A G EV K NPE KSIP KAILQV I WRITIF Y ILSLLAI G LLVPW nd PG L LNDSAS A ASPFVIFFKFLGI S gl APL I NAVILTAAL 292
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 573 G A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHSKAN G E P TW A L L LTAA I AE L GI L I ASL dl VAP I LSM F F L MCYLFVN L AC 652
Cdd:pfam00324 293 S A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L ASL -- NPA I VFN F L L AISGLSG L IV 368
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 653 ALQTL L RTPNW R PR F R Y YHWALSFMGMSIC L ALMFISSWYY AI VAMV I AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAARFA 732
Cdd:pfam00324 369 WGLIS L SHLRF R KA F K Y QGRSIDELPFKAP L GPLGVILGLA AI IIIL I IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVLLF 448
570
....*....|....*....
gi 110224456 733 L LR L EEGPP H T KNW R PQLL 751
Cdd:pfam00324 449 L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
189-711
3.09e-35
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 140.03
E-value: 3.09e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 189 N I F G VIL F LRLTWVV G T AG -- VLQ A FA I VLICC cct M L T A I S MSAI A TN gv V P - AGG S Y FMIS RALGP EF G GAV G LCFY L 265
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG pa AIL A WL I AGLLA --- L L V A L S YAEL A SA -- F P r AGG A Y TYAR RALGP LL G FLA G WALL L 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 266 GTTF A A A MYILGAIE i F L VYIV P RAAIF hsddalkesaamlnnmr VYGTAFLV L MV L VVFI GV RYVN K FASLFLACVIVS 345
Cdd:COG0531 100 SYVL A V A AVAVAFGG - Y L SSLF P AGGSV ----------------- LIALVLIL L LT L LNLR GV KESA K VNNILTVLKLLV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 346 I L AIYA gaikssfapphfpvcmlgnrtlssrhidvcsktkeinnmtvpskl W G F F cnssqffnatcde Y F VHN N V T SIQG 425
Cdd:COG0531 162 L L LFIV --------------------------------------------- V G L F ------------- A F DPA N F T PFLP 183
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 426 IP G LA SG I itenlwsnylpkgeiiekpsakssdvlgslnheyvlvditts FTL L VGI FF p SV TG IM A GS N RSGDL K DAQK 505
Cdd:COG0531 184 AG G GL SG V ------------------------------------------ LAA L ALA FF - AF TG FE A IA N LAEEA K NPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 506 S IP IGT IL AI L TTSFV Y lsnv V L FGACIE GVV LR D KFGDAVKGNLVVGTLSWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 583
Cdd:COG0531 221 N IP RAI IL SL L IVGVL Y ---- I L VSLALT GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 584 RLL Q A I A K D NII P fl R VF GH - SKAN G E P TW A L LLT AA IA E L GI L I -- AS LDLV A PIL S MFF L MC YL F V N LA c ALQTLL R T 660
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA - VIVLRR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 110224456 661 P NWRPR FR YYHWALSFM G MSI CL A L MFIS --- SWYYAI V AMV I AGMI Y KYIEYQ 711
Cdd:COG0531 374 P DLPRP FR VPLPLIPIL G ILL CL F L LYLL gpg ALLIGL V LLA I GLLL Y LLYRRR 427
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
100-1141
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1356.69
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 100 HKKARNAYLNNSNYE EG DEYFDK N LALF EE EM D TRP KV S SLL NRM A N YTN LT QG A KEHEEAE NITEG K K KP - TKTPQM G T 178
Cdd:TIGR00930 1 NTVDAVPRIEHYRNS EG QGGPKR N RPSL EE LH D LLD KV V SLL GPL A D YTN NG QG M KEHEEAE DAEGT K E KP p AGAVKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 179 F MGV YL PCL Q NI F GVILFLRL T W V VG T AG VLQAFA I V L I CCC C T ML T AI SMSAIATNGVV PA GG S Y FM ISR A LGPEFGG A 258
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLSLL I I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISR S LGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 259 V GL C F YLGTTF A A AMY IL G AI E IF L vyivpra AIFHSD d AL K ESAAML N NM R V YGT AFL V LMVLVV F I G VRYV NK FAS LF 338
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L ------- DLLREN - GS K IMVDPI N DI R I YGT VTV V VLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 339 L AC V IV SIL A I YA G A I KSS F AP P HFPVCM LGN RT lssrhidvcsktkeinnmtvpsklwgffcnssqffnatcdey F VH N 418
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA F DK P AKGFFG LGN EI ------------------------------------------ F SE N 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 419 N vts I Q GIPG LAS G iitenlwsnylpkgeiiekpsakssdvlgslnheyvlvditts F TL L V GIFFPSVTGI M AG S N R SG 498
Cdd:TIGR00930 271 F --- I P GIPG PEG G ------------------------------------------- F FS L F GIFFPSVTGI L AG A N I SG 304
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 499 DLKD A QK S IP I GT I LAILTT SF VYL SN VVLFGAC IEGVVLR DK FGDA V K --------------------- G NL V V GT L SW 557
Cdd:TIGR00930 305 DLKD P QK A IP K GT L LAILTT TV VYL GS VVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS 384
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 558 P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG HSKA - NGEP TW A L LLTA A IAE LG ILIA S L DLV API 636
Cdd:TIGR00930 385 P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG KGYG k NGEP LR A Y LLTA F IAE GF ILIA E L NTI API 464
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 637 L S M FFL MC Y LFV N LA C ALQT LLR T P N WRPRF R YYHW A LS FM G M S I C L A L MF IS SW YY A I VAMVIA GMI YKY IE Y QGAEKE 716
Cdd:TIGR00930 465 I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRF K YYHW W LS LL G A S L C C A I MF LI SW WA A L VAMVIA LFL YKY VT Y KKPDVN 544
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 717 WG DGIRG LS L S A A RFA LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KH P R LL T FASQ LKA GKGL T I V GSVI V G NF LE NYG 796
Cdd:TIGR00930 545 WG SSTQA LS Y S L A LYS LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVI Q G PR LE CVK 620
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 797 EA L AAE QT I KHLM E AE KVK G F CQL VVA AK LREG IS HLIQ SC GLG G MK H NT V VMG WPNG WRQ S E d A RAW K T F IG TVRVTTA 876
Cdd:TIGR00930 621 EA Q AAE AK I QTWL E KN KVK A F YAV VVA DD LREG VR HLIQ AS GLG R MK P NT L VMG YKKD WRQ A E - P RAW E T Y IG IIHDAFD 699
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 877 AHLA LL V AK N ISFF P SN V -------------------------------------- EQFSE G N IDVWW I V H DGG MLM LLP 918
Cdd:TIGR00930 700 AHLA VV V VR N SEGL P IS V lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP 779
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 919 F LL KQH KVW R KC S IRIF TV AQ LE D N S I Q M KKD L AT F LY HL RI E AEV E VV E M hds DI S A yt YER T LM ME QRSQ M L R HM RL S 998
Cdd:TIGR00930 780 Y LL TTK KVW K KC K IRIF VG AQ KD D R S E Q E KKD M AT L LY KF RI D AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H 854
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 999 KTE R DREA qlv KD R nsmlrltsigsdedeetetyqekv H MTWTK DKYMAS rgqkaksmegf QD L lnmrpd QSNVR RMHTA 1078
Cdd:TIGR00930 855 KTE K DREA --- KD P ------------------------ K MTWTK PWKITD ----------- AE L ------ QSNVR KSYRQ 890
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 110224456 1079 V K LNE VIVNK S HE A K LV L L NM P G P PRNPEG DE N YM EF LEVL T E G L ER VLLVRG GGSE V I T I YS 1141
Cdd:TIGR00930 891 V R LNE LLLEY S RD A A LV V L SL P V P RKGSIP DE L YM AW LEVL S E D L PP VLLVRG NHRN V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
181-751
1.63e-48
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 180.21
E-value: 1.63e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 181 G V YLPC L QNIF G VI LF LRLTW V V G T AG VLQ A FAIV LI CCCCTM L TAI S MSA I A TNG V V p A GG S Y FMI SR A LGP EF G G A V G 260
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGS V L G Q AG PAG A LLGY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 261 L -- CFYLG T TF A AA myi L G A IE I FLVYIVPRAA I fhsddalkesaaml NNMR V Y G TA FLVL MVLVVFI GV RYVNKFASL F 338
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS I LIQFWELVPD I -------------- PYLW V W G AV FLVL LTIINLV GV KWYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 339 LACV I VS I LAIYAGA I -- K S SFA P PHFPV cmlgnrtlssrhidvcsktkeinnmtvpsklwgffcnssqffnatcd EYFV 416
Cdd:pfam00324 143 ALIK I IA I IGFIIVG I il L S GGN P NDGAI ----------------------------------------------- FRYL 175
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 417 HN N VTSIQGI PG LAS G I I tenlwsnylpkgeiiekpsakssdvlgslnhe Y V L V dittsftllvg I F F PSV TGI MAGSNR 496
Cdd:pfam00324 176 GD N GGKNNFP PG FGK G F I -------------------------------- S V F V ----------- I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 497 S G DL K DAQ KSIP IGTILA I LTTSFV Y LSNVVLF G ACIEG -- VV L RDKFGD A VKGNLVVGTLSWP S -- PWV I VIGSFFSTC 572
Cdd:pfam00324 213 A G EV K NPE KSIP KAILQV I WRITIF Y ILSLLAI G LLVPW nd PG L LNDSAS A ASPFVIFFKFLGI S gl APL I NAVILTAAL 292
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 573 G A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHSKAN G E P TW A L L LTAA I AE L GI L I ASL dl VAP I LSM F F L MCYLFVN L AC 652
Cdd:pfam00324 293 S A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L ASL -- NPA I VFN F L L AISGLSG L IV 368
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 653 ALQTL L RTPNW R PR F R Y YHWALSFMGMSIC L ALMFISSWYY AI VAMV I AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAARFA 732
Cdd:pfam00324 369 WGLIS L SHLRF R KA F K Y QGRSIDELPFKAP L GPLGVILGLA AI IIIL I IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVLLF 448
570
....*....|....*....
gi 110224456 733 L LR L EEGPP H T KNW R PQLL 751
Cdd:pfam00324 449 L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
189-711
3.09e-35
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 140.03
E-value: 3.09e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 189 N I F G VIL F LRLTWVV G T AG -- VLQ A FA I VLICC cct M L T A I S MSAI A TN gv V P - AGG S Y FMIS RALGP EF G GAV G LCFY L 265
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG pa AIL A WL I AGLLA --- L L V A L S YAEL A SA -- F P r AGG A Y TYAR RALGP LL G FLA G WALL L 99
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 266 GTTF A A A MYILGAIE i F L VYIV P RAAIF hsddalkesaamlnnmr VYGTAFLV L MV L VVFI GV RYVN K FASLFLACVIVS 345
Cdd:COG0531 100 SYVL A V A AVAVAFGG - Y L SSLF P AGGSV ----------------- LIALVLIL L LT L LNLR GV KESA K VNNILTVLKLLV 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 346 I L AIYA gaikssfapphfpvcmlgnrtlssrhidvcsktkeinnmtvpskl W G F F cnssqffnatcde Y F VHN N V T SIQG 425
Cdd:COG0531 162 L L LFIV --------------------------------------------- V G L F ------------- A F DPA N F T PFLP 183
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 426 IP G LA SG I itenlwsnylpkgeiiekpsakssdvlgslnheyvlvditts FTL L VGI FF p SV TG IM A GS N RSGDL K DAQK 505
Cdd:COG0531 184 AG G GL SG V ------------------------------------------ LAA L ALA FF - AF TG FE A IA N LAEEA K NPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 506 S IP IGT IL AI L TTSFV Y lsnv V L FGACIE GVV LR D KFGDAVKGNLVVGTLSWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 583
Cdd:COG0531 221 N IP RAI IL SL L IVGVL Y ---- I L VSLALT GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 584 RLL Q A I A K D NII P fl R VF GH - SKAN G E P TW A L LLT AA IA E L GI L I -- AS LDLV A PIL S MFF L MC YL F V N LA c ALQTLL R T 660
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA - VIVLRR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 110224456 661 P NWRPR FR YYHWALSFM G MSI CL A L MFIS --- SWYYAI V AMV I AGMI Y KYIEYQ 711
Cdd:COG0531 374 P DLPRP FR VPLPLIPIL G ILL CL F L LYLL gpg ALLIGL V LLA I GLLL Y LLYRRR 427
SLC12
pfam03522 Solute carrier family 12;
765-1141
5.22e-31
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 126.96
E-value: 5.22e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 765 P R L LT FA SQLKAGKG L T I V G S V IV G NFLENYGEA L AAE qt IKHLMEAE K V K G F CQ LV VAAK LREG ISH L I Q SC GLG GM K H 844
Cdd:pfam03522 2 P A L VD FA HLITKNVS L M I C G H V VK G RLSQKLRSE L QKK -- AYRWLRKR K I K A F YA LV DGDN LREG AQA L L Q AS GLG KL K P 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 845 N TVV MG WPNG WR QSE ------------ DA --------------------------------------------------- 861
Cdd:pfam03522 80 N ILL MG YKSD WR TCD keeleeyfnvih DA fdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 862 -- RAWKTFIGTVRVTTAAH L ALLV ------------------- AKN I SFFPSNV E -------- QF ---- SE G N IDVWW IV 908
Cdd:pfam03522 160 ns KQDDDKSKLSKKDSNLS L SPDK stknpsgkdssksdklkkk SPS I ILRTASN E keilnnit QF qkkq KK G T IDVWW LY 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 909 H DGG MLM LLP FL L KQHKV W RK C SI R I F TVAQLE D NSIQMKKDL A TF L YHL RI E - AEVE V V emhd S DI SAYTYER T LMMEQ 987
Cdd:pfam03522 240 D DGG LTL LLP YI L STRSK W SD C KL R V F ALGNRK D ELEEEQRNM A SL L SKF RI D y SDLT V I ---- P DI TKKPKKE T KKFFD 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 988 rs QMLRHM RL SKTERDR E aqlvkdrn S MLRL T sigsde D E E T E TYQ EK VH mtwtkdkymasrgqkaksmegfqdl LNM R p 1067
Cdd:pfam03522 316 -- ELIEPF RL HEDDKEE E -------- S AEKI T ------ D S E L E ALK EK TN ------------------------- RQL R - 353
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 110224456 1068 dqsnvrrmhtavk L N E VIVNK S HE A K L VLLNM P G P PRNPEGDEN YM EF LE V LT EG L ERV LLVRG GGSE V I T I YS 1141
Cdd:pfam03522 354 ------------- L R E LLLEH S SD A N L IVMTL P M P RKGTVSAPL YM AW LE T LT KD L PPF LLVRG NQTS V L T F YS 414
AA_permease_2
pfam13520 Amino acid permease;
472-708
1.20e-14
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 77.74
E-value: 1.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 472 ITTS F TLLV G IFF p S V TG IMAGS N R S GDL K da QKSI P IGTILAILTTSFV Y - L S N VVL FG AC - IEGVV L RDKF G D --- AV 546
Cdd:pfam13520 187 WPGV F AGFL G VLW - S F TG FESAA N V S EEV K -- KRNV P KAIFIGVIIVGVL Y i L V N IAF FG VV p DDEIA L SSGL G Q vaa LL 263
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 547 KGNLVVGTLSW pspw VI VI GSFF S TC GA GLQSLT GA P RLL Q A I A K D NII PF L R V F GHSKAN G E P TW A LL LTA AIAELGI L 626
Cdd:pfam13520 264 FQAVGGKWGAI ---- IV VI LLAL S LL GA VNTAIV GA S RLL Y A L A R D GVL PF S R F F AKVNKF G S P IR A II LTA ILSLILL L 339
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 627 IAS L DLV A PI ---- LS MFFLMCYLFVNLACA L qt L LR TPNWRPRFRYYH W ALSFM G M s ICLALMFISSWYYAIVAMVIAG 702
Cdd:pfam13520 340 LFL L SPA A YN alls LS AYGYLLSYLLPIIGL L -- I LR KKRPDLGRIPGR W PVAIF G I - LFSLFLIVALFFPPVGPATGSS 416
....*.
gi 110224456 703 MI Y KY I 708
Cdd:pfam13520 417 LN Y AI I 422
2A0308
TIGR00911 L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
498-697
6.36e-05
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 273332 [Multi-domain]
Cd Length: 501
Bit Score: 47.05
E-value: 6.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 498 GDL K DAQKSI PI GT I LAILTTS F V Y - L S N VVL F GACIEGVV L RDKFGDAVK G NLVV G TL SW PS P wv IVI G sf F S TC G AGL 576
Cdd:TIGR00911 259 EEV K NPYRTL PI AI I ISMPIVT F I Y v L T N IAY F TVLSPEEL L ASLAVAVDF G ERLL G VM SW AM P -- ALV G -- L S CF G SVN 334
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110224456 577 Q SL TGAP RL LQAIAKDNII P F L RVFG H S K AN g E P TWA LL LTAAIAE L GILIASLDLVAPIL S MFF lmc Y LF VN LA C A LQT 656
Cdd:TIGR00911 335 G SL FSSS RL FFVGGREGHL P S L LSMI H V K RL - T P LPS LL IVCTLTL L MLFSGDIYSLINLI S FAN --- W LF NA LA V A GLL 410
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 110224456 657 L LR -- T P NWRPRFR yyhwalsfmg MSICLALM F IS S WYYA I VA 697
Cdd:TIGR00911 411 W LR yk R P EMNRPIK ---------- VPLFFPVF F LL S CLFL I IL 443
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
