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Conserved domains on  [gi|110349761|ref|NP_001036014|]
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kinetochore-associated protein NSL1 homolog isoform 2 [Homo sapiens]

Protein Classification

Mis14 domain-containing protein( domain architecture ID 10554535)

Mis14 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mis14 pfam08641
Kinetochore protein Mis14 like; Mis14 is a kinetochore protein which is known to be recruited ...
 82-166 2.75e-23

Kinetochore protein Mis14 like; Mis14 is a kinetochore protein which is known to be recruited to kinetochores independently of CENP-A.


:

Pssm-ID: 430124  Cd Length: 136  Bit Score: 90.57  E-value: 2.75e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110349761   82 SAVQENISINGQAWQEASDNCF------------------MDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKA 143
Cdd:pfam08641   1 EMAQDSVVINGLDWSASSSVSIldllsespeeevepfdleLNEKVRSLYQEWEDETVEVAQLRRSGPRKIAEAYVKSLKA 80

                          90       100
                  ....*....|....*....|...
gi 110349761  144 KQEILKQYHPVVHPLDLKYDPDP 166
Cdd:pfam08641  81 QLKELDAYLPAINPLELEEEKDP 103
 
Name Accession Description Interval E-value
Mis14 pfam08641
Kinetochore protein Mis14 like; Mis14 is a kinetochore protein which is known to be recruited ...
 82-166 2.75e-23

Kinetochore protein Mis14 like; Mis14 is a kinetochore protein which is known to be recruited to kinetochores independently of CENP-A.


Pssm-ID: 430124  Cd Length: 136  Bit Score: 90.57  E-value: 2.75e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110349761   82 SAVQENISINGQAWQEASDNCF------------------MDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKA 143
Cdd:pfam08641   1 EMAQDSVVINGLDWSASSSVSIldllsespeeevepfdleLNEKVRSLYQEWEDETVEVAQLRRSGPRKIAEAYVKSLKA 80

                          90       100
                  ....*....|....*....|...
gi 110349761  144 KQEILKQYHPVVHPLDLKYDPDP 166
Cdd:pfam08641  81 QLKELDAYLPAINPLELEEEKDP 103
 
Name Accession Description Interval E-value
Mis14 pfam08641
Kinetochore protein Mis14 like; Mis14 is a kinetochore protein which is known to be recruited ...
 82-166 2.75e-23

Kinetochore protein Mis14 like; Mis14 is a kinetochore protein which is known to be recruited to kinetochores independently of CENP-A.


Pssm-ID: 430124  Cd Length: 136  Bit Score: 90.57  E-value: 2.75e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110349761   82 SAVQENISINGQAWQEASDNCF------------------MDSDIKVLEDQFDEIIVDIATKRKQYPRKILECVIKTIKA 143
Cdd:pfam08641   1 EMAQDSVVINGLDWSASSSVSIldllsespeeevepfdleLNEKVRSLYQEWEDETVEVAQLRRSGPRKIAEAYVKSLKA 80

                          90       100
                  ....*....|....*....|...
gi 110349761  144 KQEILKQYHPVVHPLDLKYDPDP 166
Cdd:pfam08641  81 QLKELDAYLPAINPLELEEEKDP 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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