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Conserved domains on  [gi|124486622|ref|NP_001074492|]
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voltage-dependent L-type calcium channel subunit alpha-1S isoform 2 [Mus musculus]

Protein Classification

Ca_chan_IQ domain-containing protein; Ca_chan_IQ domain-containing protein; voltage-dependent L-type calcium channel subunit alpha-1; voltage-dependent L-type calcium channel subunit alpha-1( domain architecture ID 11999372)

Ca_chan_IQ domain-containing protein; Ca_chan_IQ domain-containing protein; voltage-dependent L-type (Long-lasting) calcium channel subunit alpha-1 is part of a multisubunit voltage-dependent calcium channel that mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death; voltage-dependent L-type (Long-lasting) calcium channel subunit alpha-1 is part of a multisubunit voltage-dependent calcium channel that mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1117-1392 6.03e-66

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 223.68  E-value: 6.03e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1117 SSYFEYLMFALIMLNTICLGMQHYNQSEQ-MNHISDILNVAFTIIFTLEMVLKLIAFKP-RGYFGDPWNVFDFLIVIGSI 1194
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1195 IDVILSEIDTFLASSgglyclgggcgnvdpdesarissaFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLI 1274
Cdd:pfam00520   81 ISLVLSSVGSLSGLR------------------------VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLL 136
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1275 VMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKlcdpesdyapgeehtcGT 1354
Cdd:pfam00520  137 LLFLFIFAIIGYQLFGGKLKTWENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGK----------------GE 200
                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 124486622  1355 NFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWS 1392
Cdd:pfam00520  201 FWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
50-345 9.29e-61

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 208.66  E-value: 9.29e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622    50 WKPFETIILLTIFANCVALAVYLPMPEDDnnTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHqdaYLRSGWNVLDFII 129
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEE--PLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   130 VFLGVFTVIleqvniiqtntapMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVII 209
Cdd:pfam00520   76 VLPSLISLV-------------LSSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFI 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   210 YAIIGLELFKGKMHKtcyfigtdivatvenekpspcartgsgrpctingsecrggWPGPNHGITHFDNFGFSMLTVYQCI 289
Cdd:pfam00520  143 FAIIGYQLFGGKLKT----------------------------------------WENPDNGRTNFDNFPNAFLWLFQTM 182
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 124486622   290 SMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAK 345
Cdd:pfam00520  183 TTEGWGDIMYDTIDGKGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
798-1075 2.23e-50

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 178.61  E-value: 2.23e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   798 ATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHkgsFCRNYFNILDLLVVA 877
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVL 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   878 VSLISMGL-ESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYS 956
Cdd:pfam00520   78 PSLISLVLsSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKT 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   957 cndlskmteeecrgyyyiykdgdptqielrPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYn 1036
Cdd:pfam00520  158 ------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEFWAYIY- 206
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 124486622  1037 nrvemaifFIIYIILIAFFMMNIFVGFVIVTFQEQGETE 1075
Cdd:pfam00520  207 --------FVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
431-672 3.23e-49

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


:

Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 175.53  E-value: 3.23e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   431 SKVFYWLVILIVALNTLSIASEHHNQPLW-LTHLQDVANRVLLTLFTIEMLMKMYGLGL-RQYFMSIFNRFDCFVVCSGI 508
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   509 LEILLveSGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYD-F 587
Cdd:pfam00520   81 ISLVL--SSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKtW 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   588 EDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYpgvlvCIYFIILFVCGNYILLNVFLAIAVDNLAEA 667
Cdd:pfam00520  159 ENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEFWA-----YIYFVSFIILGGFLLLNLFIAVIIDNFQEL 233

                   ....*
gi 124486622   668 ESLTS 672
Cdd:pfam00520  234 TERTE 238
Ca_chan_IQ pfam08763
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1464-1536 1.16e-34

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


:

Pssm-ID: 462591  Cd Length: 77  Bit Score: 127.71  E-value: 1.16e-34
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124486622  1464 NATLFALVRTALKIKTE--GNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF 1536
Cdd:pfam08763    1 TATLFALIRTSLKIKLApaGEMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQN 75
GPHH pfam16905
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ...
1401-1454 1.03e-29

Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.


:

Pssm-ID: 465306  Cd Length: 54  Bit Score: 112.75  E-value: 1.03e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 124486622  1401 EFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMP 1454
Cdd:pfam16905    1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
CAC1F_C super family cl25181
Voltage-gated calcium channel subunit alpha, C-term; CAC1F_C is the C-terminal region of ...
1557-1840 8.26e-07

Voltage-gated calcium channel subunit alpha, C-term; CAC1F_C is the C-terminal region of voltage-gated calcium channel subunit alpha in higher eukaryotes. The exact function of this domain is not known.This region lies immediately downstream from the CDB motif, pfam08673.


The actual alignment was detected with superfamily member pfam16885:

Pssm-ID: 465298 [Multi-domain]  Cd Length: 355  Bit Score: 53.47  E-value: 8.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1557 AGLRTIEEeAAPEIHRAISGDlTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVMANQRPLQFAEIEME 1636
Cdd:pfam16885    1 AGLRSLQD-LGPEIRQALTCD-TEEEEEEEEGQEGEEEEDSKDPKAPIGSQPPSRSRISVSLPVGDRLPDSLSLGPSDDD 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1637 ELESPVFLEDFPQnPGTHPLARANTNNANANVAYGNSSHRNNPVFSSICYEREFLGEADMPVTREGPLSQPCRASgPHSR 1716
Cdd:pfam16885   79 GGAPNSRQPSVPQ-TGSHTHRRSSGVLMFTIPEEGSSQPKGTKGQDKQDEEEEVPDQLSYLDEQAGTPSRPVLLP-PHRP 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1717 SHVDKLKRPMTQRGMP---EGQVP----------------PSPCQVTGAKAEHPVQKEGKGPTS----RFLETP------ 1767
Cdd:pfam16885  157 QHYPLREPVDRRRLLPptpAGRKPsfniqclrrqgscedlPIPGTYHRGRNSGPSRAQGSWATPpqrgRLLYAPlllvee 236
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1768 -------------NSRNFEE-HVPR---NSAHRCTAPATAmLIQEALVRGGLDSLAADANFVMATGQALADACQMEPEEV 1830
Cdd:pfam16885  237 gaagegylgkspgPLRTFTClRVPGthsDPSHGKRGSADS-LVEAVLISEGLGLFAQDPKFVALAKQEIADACHLTLDEM 315
                          330
                   ....*....|
gi 124486622  1831 EVAATELLKQ 1840
Cdd:pfam16885  316 DSAASDLLAQ 325
 
Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1117-1392 6.03e-66

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 223.68  E-value: 6.03e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1117 SSYFEYLMFALIMLNTICLGMQHYNQSEQ-MNHISDILNVAFTIIFTLEMVLKLIAFKP-RGYFGDPWNVFDFLIVIGSI 1194
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1195 IDVILSEIDTFLASSgglyclgggcgnvdpdesarissaFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLI 1274
Cdd:pfam00520   81 ISLVLSSVGSLSGLR------------------------VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLL 136
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1275 VMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKlcdpesdyapgeehtcGT 1354
Cdd:pfam00520  137 LLFLFIFAIIGYQLFGGKLKTWENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGK----------------GE 200
                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 124486622  1355 NFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWS 1392
Cdd:pfam00520  201 FWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
50-345 9.29e-61

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 208.66  E-value: 9.29e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622    50 WKPFETIILLTIFANCVALAVYLPMPEDDnnTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHqdaYLRSGWNVLDFII 129
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEE--PLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   130 VFLGVFTVIleqvniiqtntapMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVII 209
Cdd:pfam00520   76 VLPSLISLV-------------LSSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFI 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   210 YAIIGLELFKGKMHKtcyfigtdivatvenekpspcartgsgrpctingsecrggWPGPNHGITHFDNFGFSMLTVYQCI 289
Cdd:pfam00520  143 FAIIGYQLFGGKLKT----------------------------------------WENPDNGRTNFDNFPNAFLWLFQTM 182
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 124486622   290 SMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAK 345
Cdd:pfam00520  183 TTEGWGDIMYDTIDGKGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
798-1075 2.23e-50

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 178.61  E-value: 2.23e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   798 ATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHkgsFCRNYFNILDLLVVA 877
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVL 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   878 VSLISMGL-ESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYS 956
Cdd:pfam00520   78 PSLISLVLsSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKT 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   957 cndlskmteeecrgyyyiykdgdptqielrPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYn 1036
Cdd:pfam00520  158 ------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEFWAYIY- 206
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 124486622  1037 nrvemaifFIIYIILIAFFMMNIFVGFVIVTFQEQGETE 1075
Cdd:pfam00520  207 --------FVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
431-672 3.23e-49

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 175.53  E-value: 3.23e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   431 SKVFYWLVILIVALNTLSIASEHHNQPLW-LTHLQDVANRVLLTLFTIEMLMKMYGLGL-RQYFMSIFNRFDCFVVCSGI 508
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   509 LEILLveSGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYD-F 587
Cdd:pfam00520   81 ISLVL--SSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKtW 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   588 EDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYpgvlvCIYFIILFVCGNYILLNVFLAIAVDNLAEA 667
Cdd:pfam00520  159 ENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEFWA-----YIYFVSFIILGGFLLLNLFIAVIIDNFQEL 233

                   ....*
gi 124486622   668 ESLTS 672
Cdd:pfam00520  234 TERTE 238
Ca_chan_IQ pfam08763
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1464-1536 1.16e-34

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


Pssm-ID: 462591  Cd Length: 77  Bit Score: 127.71  E-value: 1.16e-34
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124486622  1464 NATLFALVRTALKIKTE--GNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF 1536
Cdd:pfam08763    1 TATLFALIRTSLKIKLApaGEMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQN 75
GPHH pfam16905
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ...
1401-1454 1.03e-29

Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.


Pssm-ID: 465306  Cd Length: 54  Bit Score: 112.75  E-value: 1.03e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 124486622  1401 EFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMP 1454
Cdd:pfam16905    1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
Ca_chan_IQ smart01062
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1516-1542 1.09e-10

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


Pssm-ID: 198130  Cd Length: 31  Bit Score: 58.00  E-value: 1.09e-10
                            10        20
                    ....*....|....*....|....*..
gi 124486622   1516 DEVTVGKFYATFLIQEHFRKFMKRQEE 1542
Cdd:smart01062    1 DELTVGKIYAAMLIQDYFRQFKSRKEQ 27
CAC1F_C pfam16885
Voltage-gated calcium channel subunit alpha, C-term; CAC1F_C is the C-terminal region of ...
1557-1840 8.26e-07

Voltage-gated calcium channel subunit alpha, C-term; CAC1F_C is the C-terminal region of voltage-gated calcium channel subunit alpha in higher eukaryotes. The exact function of this domain is not known.This region lies immediately downstream from the CDB motif, pfam08673.


Pssm-ID: 465298 [Multi-domain]  Cd Length: 355  Bit Score: 53.47  E-value: 8.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1557 AGLRTIEEeAAPEIHRAISGDlTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVMANQRPLQFAEIEME 1636
Cdd:pfam16885    1 AGLRSLQD-LGPEIRQALTCD-TEEEEEEEEGQEGEEEEDSKDPKAPIGSQPPSRSRISVSLPVGDRLPDSLSLGPSDDD 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1637 ELESPVFLEDFPQnPGTHPLARANTNNANANVAYGNSSHRNNPVFSSICYEREFLGEADMPVTREGPLSQPCRASgPHSR 1716
Cdd:pfam16885   79 GGAPNSRQPSVPQ-TGSHTHRRSSGVLMFTIPEEGSSQPKGTKGQDKQDEEEEVPDQLSYLDEQAGTPSRPVLLP-PHRP 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1717 SHVDKLKRPMTQRGMP---EGQVP----------------PSPCQVTGAKAEHPVQKEGKGPTS----RFLETP------ 1767
Cdd:pfam16885  157 QHYPLREPVDRRRLLPptpAGRKPsfniqclrrqgscedlPIPGTYHRGRNSGPSRAQGSWATPpqrgRLLYAPlllvee 236
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1768 -------------NSRNFEE-HVPR---NSAHRCTAPATAmLIQEALVRGGLDSLAADANFVMATGQALADACQMEPEEV 1830
Cdd:pfam16885  237 gaagegylgkspgPLRTFTClRVPGthsDPSHGKRGSADS-LVEAVLISEGLGLFAQDPKFVALAKQEIADACHLTLDEM 315
                          330
                   ....*....|
gi 124486622  1831 EVAATELLKQ 1840
Cdd:pfam16885  316 DSAASDLLAQ 325
 
Name Accession Description Interval E-value
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
1117-1392 6.03e-66

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 223.68  E-value: 6.03e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1117 SSYFEYLMFALIMLNTICLGMQHYNQSEQ-MNHISDILNVAFTIIFTLEMVLKLIAFKP-RGYFGDPWNVFDFLIVIGSI 1194
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1195 IDVILSEIDTFLASSgglyclgggcgnvdpdesarissaFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLI 1274
Cdd:pfam00520   81 ISLVLSSVGSLSGLR------------------------VLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLL 136
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1275 VMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKlcdpesdyapgeehtcGT 1354
Cdd:pfam00520  137 LLFLFIFAIIGYQLFGGKLKTWENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGK----------------GE 200
                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 124486622  1355 NFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWS 1392
Cdd:pfam00520  201 FWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
50-345 9.29e-61

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 208.66  E-value: 9.29e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622    50 WKPFETIILLTIFANCVALAVYLPMPEDDnnTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHqdaYLRSGWNVLDFII 129
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEE--PLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVV 75
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   130 VFLGVFTVIleqvniiqtntapMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVII 209
Cdd:pfam00520   76 VLPSLISLV-------------LSSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFI 142
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   210 YAIIGLELFKGKMHKtcyfigtdivatvenekpspcartgsgrpctingsecrggWPGPNHGITHFDNFGFSMLTVYQCI 289
Cdd:pfam00520  143 FAIIGYQLFGGKLKT----------------------------------------WENPDNGRTNFDNFPNAFLWLFQTM 182
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 124486622   290 SMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAK 345
Cdd:pfam00520  183 TTEGWGDIMYDTIDGKGEFWAYIYFVSFIILGGFLLLNLFIAVIIDNFQELTERTE 238
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
798-1075 2.23e-50

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 178.61  E-value: 2.23e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   798 ATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGAFLHkgsFCRNYFNILDLLVVA 877
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEPLTTVLEILDYVFTGIFTLEMLLKIIAAGFKKR---YFRSPWNILDFVVVL 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   878 VSLISMGL-ESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYS 956
Cdd:pfam00520   78 PSLISLVLsSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKT 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   957 cndlskmteeecrgyyyiykdgdptqielrPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEEDTGPVYn 1036
Cdd:pfam00520  158 ------------------------------WENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEFWAYIY- 206
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 124486622  1037 nrvemaifFIIYIILIAFFMMNIFVGFVIVTFQEQGETE 1075
Cdd:pfam00520  207 --------FVSFIILGGFLLLNLFIAVIIDNFQELTERT 237
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
431-672 3.23e-49

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 175.53  E-value: 3.23e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   431 SKVFYWLVILIVALNTLSIASEHHNQPLW-LTHLQDVANRVLLTLFTIEMLMKMYGLGL-RQYFMSIFNRFDCFVVCSGI 508
Cdd:pfam00520    1 SRYFELFILLLILLNTIFLALETYFQPEEpLTTVLEILDYVFTGIFTLEMLLKIIAAGFkKRYFRSPWNILDFVVVLPSL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   509 LEILLveSGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYD-F 587
Cdd:pfam00520   81 ISLVL--SSVGSLSGLRVLRLLRLLRLLRLIRRLEGLRTLVNSLIRSLKSLGNLLLLLLLFLFIFAIIGYQLFGGKLKtW 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622   588 EDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGIMAYGGPTYpgvlvCIYFIILFVCGNYILLNVFLAIAVDNLAEA 667
Cdd:pfam00520  159 ENPDNGRTNFDNFPNAFLWLFQTMTTEGWGDIMYDTIDGKGEFWA-----YIYFVSFIILGGFLLLNLFIAVIIDNFQEL 233

                   ....*
gi 124486622   668 ESLTS 672
Cdd:pfam00520  234 TERTE 238
Ca_chan_IQ pfam08763
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1464-1536 1.16e-34

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


Pssm-ID: 462591  Cd Length: 77  Bit Score: 127.71  E-value: 1.16e-34
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124486622  1464 NATLFALVRTALKIKTE--GNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKF 1536
Cdd:pfam08763    1 TATLFALIRTSLKIKLApaGEMDQADAELRKIIKKIWPRLSQKTLDLLVPPPSDDEMTVGKIYAALLIQDYYRQN 75
GPHH pfam16905
Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in ...
1401-1454 1.03e-29

Voltage-dependent L-type calcium channel, IQ-associated; GPHH is a sequence motif found in this short domain on voltage-dependent L-type calcium channel proteins in eukaryotes. The domain is closely associated with the IQ-domain, pfam08763.


Pssm-ID: 465306  Cd Length: 54  Bit Score: 112.75  E-value: 1.03e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 124486622  1401 EFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMP 1454
Cdd:pfam16905    1 EFVRVWAEYDPAATGRISYQDMYELLRRISPPLGFGKKCPARVAYKRLVRMNMP 54
Ca_chan_IQ smart01062
Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular ...
1516-1542 1.09e-10

Voltage gated calcium channel IQ domain; Voltage gated calcium channels control cellular calcium entry in response to changes in membrane potential. The isoleucine-glutamine (IQ) motif in the voltage gated calcium channel IQ domain interacts with hydrophobic pockets of Ca2+/calmodulin. The interaction regulates two self-regulatory calcium dependent feedback mechanism, calcium dependent inactivation (CDI), and calcium-dependent facilitation (CDF).


Pssm-ID: 198130  Cd Length: 31  Bit Score: 58.00  E-value: 1.09e-10
                            10        20
                    ....*....|....*....|....*..
gi 124486622   1516 DEVTVGKFYATFLIQEHFRKFMKRQEE 1542
Cdd:smart01062    1 DELTVGKIYAAMLIQDYFRQFKSRKEQ 27
PKD_channel pfam08016
Polycystin cation channel; This family contains the cation channel region from group II of ...
1152-1385 5.60e-09

Polycystin cation channel; This family contains the cation channel region from group II of Transient receptor potential (TRP) channels, the TRPP subfamily, including PKD1, PKD2, PKD2L and mucolipin proteins.


Pssm-ID: 462341 [Multi-domain]  Cd Length: 225  Bit Score: 58.44  E-value: 5.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1152 ILNVAFTIIFTLEMVLKLIAFKPRgYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESA--- 1228
Cdd:pfam08016   15 IVFVVFFLYFVVEEILKIRKHRPS-YLRSVWNLLDLAIVILSVVLIVLNIYRDFLADRLIKSVEASPVTFIDFDRVAqld 93
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1229 ---RISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGkiamvdgtqiNRNNN 1305
Cdd:pfam08016   94 nlyRIILAFLVFLTWLKLFKVLRFNKTMSLFTKTLSRAWKDLAGFALMFVIFFFAYAQFGYLLFG----------TQAPN 163
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1306 FQTFPQAVLLLFRcatgeawqeillacsygKLCDPESDYapgEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVIMDNFD 1385
Cdd:pfam08016  164 FSNFVKSILTLFR-----------------TILGDFGYN---EIFSGNRVLGPLLFLTFVFLVIFILLNLFLAIINDSYV 223
CAC1F_C pfam16885
Voltage-gated calcium channel subunit alpha, C-term; CAC1F_C is the C-terminal region of ...
1557-1840 8.26e-07

Voltage-gated calcium channel subunit alpha, C-term; CAC1F_C is the C-terminal region of voltage-gated calcium channel subunit alpha in higher eukaryotes. The exact function of this domain is not known.This region lies immediately downstream from the CDB motif, pfam08673.


Pssm-ID: 465298 [Multi-domain]  Cd Length: 355  Bit Score: 53.47  E-value: 8.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1557 AGLRTIEEeAAPEIHRAISGDlTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVMANQRPLQFAEIEME 1636
Cdd:pfam16885    1 AGLRSLQD-LGPEIRQALTCD-TEEEEEEEEGQEGEEEEDSKDPKAPIGSQPPSRSRISVSLPVGDRLPDSLSLGPSDDD 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1637 ELESPVFLEDFPQnPGTHPLARANTNNANANVAYGNSSHRNNPVFSSICYEREFLGEADMPVTREGPLSQPCRASgPHSR 1716
Cdd:pfam16885   79 GGAPNSRQPSVPQ-TGSHTHRRSSGVLMFTIPEEGSSQPKGTKGQDKQDEEEEVPDQLSYLDEQAGTPSRPVLLP-PHRP 156
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1717 SHVDKLKRPMTQRGMP---EGQVP----------------PSPCQVTGAKAEHPVQKEGKGPTS----RFLETP------ 1767
Cdd:pfam16885  157 QHYPLREPVDRRRLLPptpAGRKPsfniqclrrqgscedlPIPGTYHRGRNSGPSRAQGSWATPpqrgRLLYAPlllvee 236
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486622  1768 -------------NSRNFEE-HVPR---NSAHRCTAPATAmLIQEALVRGGLDSLAADANFVMATGQALADACQMEPEEV 1830
Cdd:pfam16885  237 gaagegylgkspgPLRTFTClRVPGthsDPSHGKRGSADS-LVEAVLISEGLGLFAQDPKFVALAKQEIADACHLTLDEM 315
                          330
                   ....*....|
gi 124486622  1831 EVAATELLKQ 1840
Cdd:pfam16885  316 DSAASDLLAQ 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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