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Conserved domains on  [gi|145977196|ref|NP_001078841|]
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ubiquinol-cytochrome-c reductase complex assembly factor 3 [Homo sapiens]

Protein Classification

ubiquinol-cytochrome-c reductase complex assembly factor 3( domain architecture ID 10633492)

ubiquinol-cytochrome-c reductase complex assembly factor 3 (UQCC3) is a DUF4574 domain-containing protein that is required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UQCC3 pfam15141
Ubiquinol-cytochrome-c reductase complex assembly factor 3; Complex III (cytochrome bc1) is a ...
 1-82 6.91e-44

Ubiquinol-cytochrome-c reductase complex assembly factor 3; Complex III (cytochrome bc1) is a protein complex of the mitochondrial inner membrane that transfers electrons from ubiquinol to cytochrome c. UQCC3 functions in complex III assembly. The human UQCC3 is the ortholog of the fungal complex III assembly factor CBP4. It is also a potent antiviral protein independent of interferon production.


:

Pssm-ID: 464526  Cd Length: 87  Bit Score: 136.76  E-value: 6.91e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145977196   1 MDSLRKMLISVAMLGAGAGVGYALLVIVTPGERRKQEMLKEMPLQDPRSREEAARTQQLLLATLQEAATTQENVAWRKNW 80
Cdd:pfam15141  1 MASLRKALSVVALLGAGAGVGYALFALVTPGEERKQEMLKEMPEQDPQRRDEAARTKALVMATLQEAAATQENVAWRKNW 80


                 ..
gi 145977196  81 MV 82
Cdd:pfam15141 81 MG 82
 
Name Accession Description Interval E-value
UQCC3 pfam15141
Ubiquinol-cytochrome-c reductase complex assembly factor 3; Complex III (cytochrome bc1) is a ...
 1-82 6.91e-44

Ubiquinol-cytochrome-c reductase complex assembly factor 3; Complex III (cytochrome bc1) is a protein complex of the mitochondrial inner membrane that transfers electrons from ubiquinol to cytochrome c. UQCC3 functions in complex III assembly. The human UQCC3 is the ortholog of the fungal complex III assembly factor CBP4. It is also a potent antiviral protein independent of interferon production.


Pssm-ID: 464526  Cd Length: 87  Bit Score: 136.76  E-value: 6.91e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145977196   1 MDSLRKMLISVAMLGAGAGVGYALLVIVTPGERRKQEMLKEMPLQDPRSREEAARTQQLLLATLQEAATTQENVAWRKNW 80
Cdd:pfam15141  1 MASLRKALSVVALLGAGAGVGYALFALVTPGEERKQEMLKEMPEQDPQRRDEAARTKALVMATLQEAAATQENVAWRKNW 80


                 ..
gi 145977196  81 MV 82
Cdd:pfam15141 81 MG 82
 
Name Accession Description Interval E-value
UQCC3 pfam15141
Ubiquinol-cytochrome-c reductase complex assembly factor 3; Complex III (cytochrome bc1) is a ...
 1-82 6.91e-44

Ubiquinol-cytochrome-c reductase complex assembly factor 3; Complex III (cytochrome bc1) is a protein complex of the mitochondrial inner membrane that transfers electrons from ubiquinol to cytochrome c. UQCC3 functions in complex III assembly. The human UQCC3 is the ortholog of the fungal complex III assembly factor CBP4. It is also a potent antiviral protein independent of interferon production.


Pssm-ID: 464526  Cd Length: 87  Bit Score: 136.76  E-value: 6.91e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145977196   1 MDSLRKMLISVAMLGAGAGVGYALLVIVTPGERRKQEMLKEMPLQDPRSREEAARTQQLLLATLQEAATTQENVAWRKNW 80
Cdd:pfam15141  1 MASLRKALSVVALLGAGAGVGYALFALVTPGEERKQEMLKEMPEQDPQRRDEAARTKALVMATLQEAAATQENVAWRKNW 80


                 ..
gi 145977196  81 MV 82
Cdd:pfam15141 81 MG 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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