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Conserved domains on  [gi|157694520|ref|NP_001099014|]
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ethylmalonyl-CoA decarboxylase isoform 3 [Homo sapiens]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to human ethylmalonyl-CoA decarboxylase that decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016829
PubMed:  12467702|22016388

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 1-219 3.48e-49

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 161.10  E-value: 3.48e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGG 80
Cdd:COG1024   27 MLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRLFRALRRLPKPVIAAVNGAALGG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  81 GAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqSSDETks 160
Cdd:COG1024  107 GLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELGLVNRVV-PDDEL-- 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 157694520 161 LEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 219
Cdd:COG1024  184 LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 1-219 3.48e-49

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 161.10  E-value: 3.48e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGG 80
Cdd:COG1024   27 MLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRLFRALRRLPKPVIAAVNGAALGG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  81 GAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqSSDETks 160
Cdd:COG1024  107 GLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELGLVNRVV-PDDEL-- 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 157694520 161 LEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 219
Cdd:COG1024  184 LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 1-170 1.81e-41

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 139.62  E-value: 1.81e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMF-MQNTLTRFMRLPLISVALVQGWALG 79
Cdd:cd06558   27 MLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIReLQELLRALLRLPKPVIAAVNGAALG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  80 GGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqssDETK 159
Cdd:cd06558  107 GGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISAEEALELGLVDEVV---PDEE 183

                        170
                 ....*....|.
gi 157694520 160 SLEEAQEWLKQ 170
Cdd:cd06558  184 LLAAALELARR 194
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
6-185 9.75e-25

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 101.48  E-value: 9.75e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   6 LEKVIE-LENWTEGKGLIVRGAKNTFSSGSDLNAVKSL-GTPEDG-MAVCMFMQNTLTRFMRLPLISVALVQGWALGGGA 82
Cdd:PRK11730  39 LGEALDaLEAQSDLKGLLLTSAKDAFIVGADITEFLSLfAAPEEElSQWLHFANSIFNRLEDLPVPTVAAINGYALGGGC 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  83 EFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVlqsSDETKSLE 162
Cdd:PRK11730 119 ECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVGAVDAV---VAPEKLQE 195

                        170       180
                 ....*....|....*....|....*
gi 157694520 163 EAQEWLKQFIQGPPE--VIRALKKS 185
Cdd:PRK11730 196 AALALLKQAIAGKLDwkARRQPKLE 220
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 2-206 2.48e-22

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 91.27  E-value: 2.48e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520    2 MLQLLEKvieLENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFmQNTLTRFMRLPLISVALVQGWALGGG 81
Cdd:pfam00378  28 LIQALEK---LRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENV-LDLWTLLYTCPKPVIAAVNGYAIGGG 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   82 AEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQssdETKSL 161
Cdd:pfam00378 104 CELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGLVDKVVP---EDQLL 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 157694520  162 EEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 206
Cdd:pfam00378 181 DEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY 225
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 21-153 1.28e-11

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 63.32  E-value: 1.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   21 LIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIR 100
Cdd:TIGR02441  63 VLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTL 142

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 157694520  101 FVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQ 153
Cdd:TIGR02441 143 LGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLVD 197
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 1-219 3.48e-49

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 161.10  E-value: 3.48e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGG 80
Cdd:COG1024   27 MLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRLFRALRRLPKPVIAAVNGAALGG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  81 GAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqSSDETks 160
Cdd:COG1024  107 GLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELGLVNRVV-PDDEL-- 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 157694520 161 LEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 219
Cdd:COG1024  184 LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 1-170 1.81e-41

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 139.62  E-value: 1.81e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMF-MQNTLTRFMRLPLISVALVQGWALG 79
Cdd:cd06558   27 MLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIReLQELLRALLRLPKPVIAAVNGAALG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  80 GGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqssDETK 159
Cdd:cd06558  107 GGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISAEEALELGLVDEVV---PDEE 183

                        170
                 ....*....|.
gi 157694520 160 SLEEAQEWLKQ 170
Cdd:cd06558  184 LLAAALELARR 194
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
6-185 9.75e-25

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 101.48  E-value: 9.75e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   6 LEKVIE-LENWTEGKGLIVRGAKNTFSSGSDLNAVKSL-GTPEDG-MAVCMFMQNTLTRFMRLPLISVALVQGWALGGGA 82
Cdd:PRK11730  39 LGEALDaLEAQSDLKGLLLTSAKDAFIVGADITEFLSLfAAPEEElSQWLHFANSIFNRLEDLPVPTVAAINGYALGGGC 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  83 EFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVlqsSDETKSLE 162
Cdd:PRK11730 119 ECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVGAVDAV---VAPEKLQE 195

                        170       180
                 ....*....|....*....|....*
gi 157694520 163 EAQEWLKQFIQGPPE--VIRALKKS 185
Cdd:PRK11730 196 AALALLKQAIAGKLDwkARRQPKLE 220
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 4-210 1.19e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 95.09  E-value: 1.19e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   4 QLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAE 83
Cdd:PRK07658  32 ELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSVTEAEQATELAQLGQVTFERVEKFSKPVIAAIHGAALGGGLE 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  84 FTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqssDETKSLEE 163
Cdd:PRK07658 112 LAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITGAEALKWGLVNGVF---PEETLLDD 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 157694520 164 AQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWG 210
Cdd:PRK07658 189 AKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFT 235
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 2-206 2.48e-22

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 91.27  E-value: 2.48e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520    2 MLQLLEKvieLENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFmQNTLTRFMRLPLISVALVQGWALGGG 81
Cdd:pfam00378  28 LIQALEK---LRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENV-LDLWTLLYTCPKPVIAAVNGYAIGGG 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   82 AEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQssdETKSL 161
Cdd:pfam00378 104 CELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGLVDKVVP---EDQLL 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 157694520  162 EEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 206
Cdd:pfam00378 181 DEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY 225
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 1-210 3.96e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 91.21  E-value: 3.96e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALG 79
Cdd:PRK06144  36 MYEGLAEICEAIAADPSIRAVVLRGAgDKAFVAGTDIAQFRAFSTAEDAVAYERRIDRVLGALEQLRVPTIAAIAGACVG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  80 GGAEFTTACDFRLMTPESKIRF-VHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQssDET 158
Cdd:PRK06144 116 GGAAIAAACDLRIATPSARFGFpIARTLGNCLSMSNLARLVALLGAARVKDMLFTARLLEAEEALAAGLVNEVVE--DAA 193

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 157694520 159 KSlEEAQEWLKQFIQGPPEVIRALKKSVcsgRELyLEEALQNERDLLGTVWG 210
Cdd:PRK06144 194 LD-ARADALAELLAAHAPLTLRATKEAL---RRL-RREGLPDGDDLIRMCYM 240
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
3-206 1.67e-19

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 84.03  E-value: 1.67e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   3 LQLLEKVIE-LENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLgTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGG 80
Cdd:PRK05809  33 LKELDTVLDdIENDDNVYAVILTGAgEKAFVAGADISEMKDL-NEEEGRKFGLLGNKVFRKLENLDKPVIAAINGFALGG 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  81 GAEFTTACDFRLMTpeSKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSdet 158
Cdd:PRK05809 112 GCELSMACDIRIAS--EKAKFGQPEvgLGITPGFGGTQRLARIVGPGKAKELIYTGDMINAEEALRIGLVNKVVEPE--- 186

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 157694520 159 KSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 206
Cdd:PRK05809 187 KLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFG 234
PLN02600 PLN02600
enoyl-CoA hydratase
 2-219 4.17e-19

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 82.93  E-value: 4.17e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   2 MLQLLEKVIE-LENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMfMQNTLTRFMRLPLISVALVQGWALG 79
Cdd:PLN02600  23 MLRGLRSAFEkIQADASARVVMLRSSvPGVFCAGADLKERRKMSPSEVQKFVNS-LRSTFSSLEALSIPTIAVVEGAALG 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  80 GGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDE-T 158
Cdd:PLN02600 102 GGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGLVNYCVPAGEAyE 181

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157694520 159 KSLEEAQEwlkqFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 219
Cdd:PLN02600 182 KALELAQE----INQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLA 238
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 22-203 1.72e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 81.24  E-value: 1.72e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  22 IVRGA-KNTFSSGSDLN---AVKSLGTPEDGMAvcmfmqnTLT-RF-MRLPLIsvALVQGWALGGGAEFTTACD------ 89
Cdd:PRK06494  53 IVTGAgDKAFSAGNDLKeqaAGGKRGWPESGFG-------GLTsRFdLDKPII--AAVNGVAMGGGFELALACDlivaae 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  90 ---FRLmtPESKIrfvhkemGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDetkSLEEAQE 166
Cdd:PRK06494 124 natFAL--PEPRV-------GLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREGLELGFVNEVVPAGE---LLAAAER 191

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 157694520 167 WLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERD 203
Cdd:PRK06494 192 WADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRD 228
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 2-202 3.68e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 80.55  E-value: 3.68e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   2 MLQLLEKVI-ELENWTEGKGLIVRGAKN-TFSSGSDLNAVKSLGTPEDGMAVCMfMQNTLTRFMRLPLISVALVQGWALG 79
Cdd:PRK07657  32 LLEELQNILtQINEEANVRVVILTGAGEkAFCAGADLKERAGMNEEQVRHAVSL-IRTTMEMVEQLPQPVIAAINGIALG 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  80 GGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSdetK 159
Cdd:PRK07657 111 GGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEIGLVEFVVPAH---L 187

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 157694520 160 SLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNER 202
Cdd:PRK07657 188 LEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEK 230
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 21-186 3.14e-17

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 77.19  E-value: 3.14e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  21 LIVRGAKNTFSSGSDLNAVKSLGTPEDGMA--VCmfmQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESK 98
Cdd:PRK05869  55 VILYGGHEIFSAGDDMPELRTLSAQEADTAarVR---QQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVK 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  99 IRFVHKEMGIIPSWGGTTRLVEIIGSRQALK-VLSGALkLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPE 177
Cdd:PRK05869 132 FGATEILAGLAPSGDGMARLTRAAGPSRAKElVFSGRF-FDAEEALALGLIDEMVAPDD---VYDAAAAWARRFLDGPPH 207


                 ....*....
gi 157694520 178 VIRALKKSV 186
Cdd:PRK05869 208 ALAAAKAGI 216
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 4-202 5.30e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 77.40  E-value: 5.30e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   4 QLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEdgmavcMFMQNT------LTRfMRLPLIsvALVQGWA 77
Cdd:PRK08138  39 QLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATAGAIE------MYLRHTeryweaIAQ-CPKPVI--AAVNGYA 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  78 LGGGAEFTTACDF-------RLMTPESKIrfvhkemGIIPSWGGTTRLVEIIGSRQALK-VLSGALkLDSKNALNIGMVE 149
Cdd:PRK08138 110 LGGGCELAMHADIivagesaSFGQPEIKV-------GLMPGAGGTQRLVRAVGKFKAMRmALTGCM-VPAPEALAIGLVS 181

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 157694520 150 EVlqsSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNER 202
Cdd:PRK08138 182 EV---VEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALER 231
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 1-219 6.62e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 76.83  E-value: 6.62e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV-KSLGTPEDGMAvcmfmqnTLTRFMR----LPLISVALVQG 75
Cdd:PRK06688  33 MYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFpKAPPKPPDELA-------PVNRFLRaiaaLPKPVVAAVNG 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  76 WALGGGAEFTTACDFR-------LMTPESKIrfvhkemGIIPSWGGTTRLVEIIGS-RQALKVLSGAlKLDSKNALNIGM 147
Cdd:PRK06688 106 PAVGVGVSLALACDLVyasesakFSLPFAKL-------GLCPDAGGSALLPRLIGRaRAAEMLLLGE-PLSAEEALRIGL 177

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157694520 148 VEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 219
Cdd:PRK06688 178 VNRVVPAAE---LDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGAT 246
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 1-186 1.64e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 75.53  E-value: 1.64e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV--KSLGTPEDGMAVcmfMQNTLTRFMRLPLISVALVQGWAL 78
Cdd:PRK05870  31 MSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALgaAPGRPAEDGLRR---IYDGFLAVASCPLPTIAAVNGAAV 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  79 GGGAEFTTACDFRLMTPESK--IRFVhkEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVlqsSD 156
Cdd:PRK05870 108 GAGLNLALAADVRIAGPKALfdARFQ--KLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEAAVRHGLALMV---AD 182

                        170       180       190
                 ....*....|....*....|....*....|
gi 157694520 157 ETksLEEAQEWLKQFIQGPPEVIRALKKSV 186
Cdd:PRK05870 183 DP--VAAALELAAGPAAAPRELVLATKASM 210
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
4-155 1.10e-15

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 75.32  E-value: 1.10e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   4 QLLEKVIELENWTEGKGLIVRGAK-NTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGA 82
Cdd:PRK11154  38 QVRAILKQLREDKELKGVVFISGKpDNFIAGADINMLAACKTAQEAEALARQGQQLFAEIEALPIPVVAAIHGACLGGGL 117

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157694520  83 EFTTACDFRLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALK-VLSGAlKLDSKNALNIGMVEEVLQSS 155
Cdd:PRK11154 118 ELALACHYRVCTDDPKTVLGLPEvqLGLLPGSGGTQRLPRLIGVSTALDmILTGK-QLRAKQALKLGLVDDVVPHS 192
PLN02888 PLN02888
enoyl-CoA hydratase
 1-204 1.54e-15

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 73.25  E-value: 1.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL--GTPEDGMAvcmfmqNTLTRFMRLPLISVALVQGWAL 78
Cdd:PLN02888  38 MMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAAEEVfkGDVKDVET------DPVAQMERCRKPIIGAINGFAI 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  79 GGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqssDET 158
Cdd:PLN02888 112 TAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAETAERWGLVNHVV---EES 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 157694520 159 KSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 204
Cdd:PLN02888 189 ELLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEKER 234
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 2-219 3.36e-15

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 72.11  E-value: 3.36e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   2 MLQLLEKVIELENWTEGKGLIV-RGAKNTFSSGSDLN--AVKSLGTPEDGMAVCMFMQntLTRFMRlPLIsvALVQGWAL 78
Cdd:PRK09674  30 LLTQLVNELEAAATDTSIGVCViTGNARFFAAGADLNemAEKDLAATLNDPRPQLWQR--LQAFNK-PLI--AAVNGYAL 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  79 GGGAEFTTACDfrLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALK-VLSGAlKLDSKNALNIGMVEEVLQSS 155
Cdd:PRK09674 105 GAGCELALLCD--IVIAGENARFGLPEitLGIMPGAGGTQRLIRSVGKSLASQmVLTGE-SITAQQAQQAGLVSEVFPPE 181

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157694520 156 detKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 219
Cdd:PRK09674 182 ---LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGIS 242
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 2-219 7.88e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 71.10  E-value: 7.88e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   2 MLQLLEKVIELENWTEGKGLIVRGAKNTF-SSGSDLNavkslgTPEDG-------MAVCM---FmqNTLTRFMRlplISV 70
Cdd:PRK09076  31 LQALKQLVLELNADKDVYALVITGDGEKFfSAGADLN------LFADGdkavareMARRFgeaF--EALSAFRG---VSI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  71 ALVQGWALGGGAEFTTACDFR-------LMTPESKIrfvhkemGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNAL 143
Cdd:PRK09076 100 AAINGYAMGGGLECALACDIRiaeeqaqMALPEASV-------GLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATAL 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157694520 144 NIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 219
Cdd:PRK09076 173 RIGLVEEVV---EKGEAREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVN 245
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 21-219 1.37e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 70.39  E-value: 1.37e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  21 LIVRGAKNTFSSGSDLnavKSLGTPEDGMAVCMFMQNTLTRF--MRLPLISValVQGWALGGGAEFTTACDFrLMTPEsK 98
Cdd:PRK06190  52 VVLTGADPAFCAGLDL---KELGGDGSAYGAQDALPNPSPAWpaMRKPVIGA--INGAAVTGGLELALACDI-LIASE-R 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  99 IRF--VHKEMGIIPSWGGTTRLVEIIGSRQALKV-LSGALkLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGP 175
Cdd:PRK06190 125 ARFadTHARVGILPGWGLSVRLPQKVGIGRARRMsLTGDF-LDAADALRAGLVTEVVPHDE---LLPRARRLAASIAGNN 200

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 157694520 176 PEVIRALKKSVCSGRELYLEEALQNERDLLGTvWGGPANLEAIA 219
Cdd:PRK06190 201 PAAVRALKASYDDGAAAQTGDALALEAEAARA-HNRSVSPDGIA 243
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
22-223 1.53e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 70.29  E-value: 1.53e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  22 IVRGAKNTFSSGSDL--------NAVKSLGTPEDGMA-----VCMFMQntltrfmRLPLISVALVQGWALGGGAEFTTAC 88
Cdd:PRK07509  52 ILSGEGGAFCAGLDVksvasspgNAVKLLFKRLPGNAnlaqrVSLGWR-------RLPVPVIAALEGVCFGGGLQIALGA 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  89 DFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVlqsSDETksLEEAQEWL 168
Cdd:PRK07509 125 DIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELTYTARVFSAEEALELGLVTHV---SDDP--LAAALALA 199

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520 169 KQFIQGPPEVIRALKKS-----VCSGRELYLEEALQNERdLLgtvwGGPANLEAIAKKGK 223
Cdd:PRK07509 200 REIAQRSPDAIAAAKRLinrswTASVRALLARESVEQIR-LL----LGKNQKIAVKAQMK 254
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 1-203 1.97e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 70.06  E-value: 1.97e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENwTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGG 80
Cdd:PRK07659  34 MLKELLQALKEVAE-SSAHIVVLRGNGRGFSAGGDIKMMLSSNDESKFDGVMNTISEIVVTLYTMPKLTISAIHGPAAGL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  81 GAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSdetkS 160
Cdd:PRK07659 113 GLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSATEALDLGLIDEVIGGD----F 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 157694520 161 LEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERD 203
Cdd:PRK07659 189 QTAAKQKISEWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKR 231
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
22-198 1.39e-13

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 67.80  E-value: 1.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  22 IVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIR 100
Cdd:PRK03580  51 IITGAgEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFDLDKPVI--AAVNGYAFGGGFELALAADFIVCADNASFA 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520 101 FVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSsdeTKSLEEAQEWLKQFIQGPPEVIR 180
Cdd:PRK03580 129 LPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEEALRWGIVNRVVPQ---AELMDRARELAQQLVNSAPLAIA 205

                        170
                 ....*....|....*...
gi 157694520 181 ALKKSVCSGRELYLEEAL 198
Cdd:PRK03580 206 ALKEIYRETSEMPVEEAY 223
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 5-196 6.81e-12

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 63.36  E-value: 6.81e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   5 LLEKVIELENWTEGKGLIVRGA--KNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNT-LTRFMRLPLISVALVQGWALGGG 81
Cdd:PLN03214  43 LDDALTALENDPTVRGVVFASGlrRDVFTAGNDIAELYAPKTSAARYAEFWLTQTTfLVRLLRSRLATVCAIRGACPAGG 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  82 AEFTTACDFRLMTPESKIRFVHKEMGI-IPSWGGTTRLVEIIGSRQA-LKVLSGALkLDSKNALNIGMVEEVLQSSdetK 159
Cdd:PLN03214 123 CAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAeSLLLRGRL-VRPAEAKQLGLIDEVVPAA---A 198

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 157694520 160 SLEEAQEWLKQFIQGPPEVIRALKKSV----CSGRELYLEE 196
Cdd:PLN03214 199 LMEAAASAMERALKLPSAARAATKALLreefSAAWEAYYEE 239
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
22-183 1.07e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 62.68  E-value: 1.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  22 IVRGAKNTFSSGSDLNAVKSLGTP----------EDGMAVCMFMQNTLTRF--MRLPLIsvALVQGWALGGGAEFTTACD 89
Cdd:PRK06142  55 VLSGSGKHFSYGIDLPAMAGVFGQlgkdglarprTDLRREILRLQAAINAVadCRKPVI--AAVQGWCIGGGVDLISACD 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  90 FRLMTPESKirFVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqsSDETKSLEEAQEW 167
Cdd:PRK06142 133 MRYASADAK--FSVREvdLGMVADVGSLQRLPRIIGDGHLRELALTGRDIDAAEAEKIGLVNRVY--DDADALLAAAHAT 208

                        170
                 ....*....|....*.
gi 157694520 168 LKQFIQGPPEVIRALK 183
Cdd:PRK06142 209 AREIAAKSPLAVRGTK 224
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 21-153 1.28e-11

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 63.32  E-value: 1.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   21 LIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIR 100
Cdd:TIGR02441  63 VLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTL 142

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 157694520  101 FVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQ 153
Cdd:TIGR02441 143 LGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLVD 197
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 69-204 4.79e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 60.87  E-value: 4.79e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  69 SVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMV 148
Cdd:PRK06127 109 TIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDAAEALRIGLV 188

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 157694520 149 EEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKSVcsgRELYLEEAlqnERDL 204
Cdd:PRK06127 189 HRVTAADD----LEtALADYAATIAGNAPLTLRAAKRAI---AELLKDEP---ERDM 235
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 17-204 6.44e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 60.44  E-value: 6.44e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  17 EGKGLIV-RGAKNTFSSGSDLNAVKSLgtpeDGMAVcmFMQNTLT-----RFMRLPLIsvALVQGWALGGGAEFTTACDF 90
Cdd:PRK05862  47 EGIGAIViTGSEKAFAAGADIKEMADL----SFMDV--YKGDYITnwekvARIRKPVI--AAVAGYALGGGCELAMMCDI 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  91 -------RLMTPESKirfvhkeMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSdetKSLEE 163
Cdd:PRK05862 119 iiaadtaKFGQPEIK-------LGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERAGLVSRVVPAD---KLLDE 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 157694520 164 AQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 204
Cdd:PRK05862 189 ALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRL 229
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 21-198 9.31e-11

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 59.92  E-value: 9.31e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  21 LIVRGAKNTFSSGSDLNAVKSL----GTPEDGMAV------CMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDF 90
Cdd:PLN02664  56 IILSGAGDHFCSGIDLKTLNSIseqsSSGDRGRSGerlrrkIKFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDI 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  91 RLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDEtksLEEAQEWLKQ 170
Cdd:PLN02664 136 RYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELALTGRRFSGSEAKELGLVSRVFGSKED---LDEGVRLIAE 212

                        170       180
                 ....*....|....*....|....*....
gi 157694520 171 FIQG-PPEVIRALKKSVCSGRELYLEEAL 198
Cdd:PLN02664 213 GIAAkSPLAVTGTKAVLLRSRELSVEQGL 241
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 21-204 1.64e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 59.16  E-value: 1.64e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  21 LIVRGAKNTFSSGSDLN--AVKSLGTPED-GMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPES 97
Cdd:PRK08140  51 LLLTGAGRGFCAGQDLAdrDVTPGGAMPDlGESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSA 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  98 KirFVHK--EMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGP 175
Cdd:PRK08140 131 S--FIQAfvKIGLVPDSGGTWFLPRLVGMARALGLALLGEKLSAEQAEQWGLIWRVV---DDAALADEAQQLAAHLATQP 205

                        170       180
                 ....*....|....*....|....*....
gi 157694520 176 PEVIRALKKSVCSGRELYLEEALQNERDL 204
Cdd:PRK08140 206 TRGLALIKQAMNASATNTLDAQLDLERDL 234
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
 30-185 1.07e-09

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 56.79  E-value: 1.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   30 FSSGSDlNAVKSLGTPEDGMAVCMFMQNTLTRFMR-LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGI 108
Cdd:TIGR01929  61 FCSGGD-QKVRGDYGYIDDSGVHRLNVLDVQRQIRtCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGS 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157694520  109 IPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKS 185
Cdd:TIGR01929 140 FDGGYGSSYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLAD----LEkETVRWCREILQKSPMAIRMLKAA 213
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
4-208 1.09e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 56.54  E-value: 1.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   4 QLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV---KSLGTPEDGMAvcmfmqnTLT-RFMRLPLIsvALVQGWALG 79
Cdd:PRK08252  34 GLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAFargERPSIPGRGFG-------GLTeRPPRKPLI--AAVEGYALA 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  80 GGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALK-VLSGALkLDSKNALNIGMVEEVlqsSDET 158
Cdd:PRK08252 105 GGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMElALTGDM-LTAERAHELGLVNRL---TEPG 180

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 157694520 159 KSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTV 208
Cdd:PRK08252 181 QALDAALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPV 230
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 1-217 1.18e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 56.57  E-value: 1.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENwTEGKGLIVRGAKNTFSSGSDLNAVkslGTPEDGMAVCMFMQNTLTRfmrLPLISVALVQGWALGG 80
Cdd:PRK07854  28 LCEELREAVRKAVD-ESARAIVLTGQGTVFCAGADLSGD---VYADDFPDALIEMLHAIDA---APVPVIAAINGPAIGA 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  81 GAEFTTACDFRLMTPESKIRFVHKEMGI-IPSWgGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVlqssdetK 159
Cdd:PRK07854 101 GLQLAMACDLRVVAPEAYFQFPVAKYGIaLDNW-TIRRLSSLVGGGRARAMLLGAEKLTAEQALATGMANRI-------G 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 157694520 160 SLEEAQEWLKQFIQGPPEVIRALKKSVCSGRElyLEEALQNERDLLGTVWGGPANLEA 217
Cdd:PRK07854 173 TLADAQAWAAEIAGLAPLALQHAKRVLNDDGA--IEEAWPAHKELFDKAWASQDAIEA 228
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
25-201 2.77e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 55.67  E-value: 2.77e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  25 GAKNTFSSGSDLNAVkslGTPE--------DG-MAVcmfmqntlTRfMRL--PLIsvALVQGWALGGGAEFTTACDFRLM 93
Cdd:PRK08259  55 GAGGTFCAGADLKAV---GTGRgnrlhpsgDGpMGP--------SR-MRLskPVI--AAVSGYAVAGGLELALWCDLRVA 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  94 TPESKI-----RFvhkemGIIPSWGGTTRLVEIIGSRQALK-VLSGAlKLDSKNALNIGMVEEVLQSSDetkSLEEAQEW 167
Cdd:PRK08259 121 EEDAVFgvfcrRW-----GVPLIDGGTVRLPRLIGHSRAMDlILTGR-PVDADEALAIGLANRVVPKGQ---ARAAAEEL 191

                        170       180       190
                 ....*....|....*....|....*....|....
gi 157694520 168 LKQFIQGPPEVIRALKKSVCSGRELYLEEALQNE 201
Cdd:PRK08259 192 AAELAAFPQTCLRADRLSALEQWGLPEEAALANE 225
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 2-197 4.65e-09

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 55.01  E-value: 4.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   2 MLQLLEkviELENWTEGKGLIVRGAKNTFSSGSDLNAV--KSLGTPEdgMAVCMFMQNTLTRFMRL---PLISVALVQGW 76
Cdd:PRK09120  40 MIDVLD---ALEFDDDAGVLVLTGAGDAWSAGMDLKEYfrETDAQPE--ILQERIRREAYGWWRRLrwyQKPTIAMVNGW 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  77 ALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQAL-KVLSGALkLDSKNALNIGMVEEVLQSS 155
Cdd:PRK09120 115 CFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALyYIMTGET-FTGRKAAEMGLVNESVPLA 193

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 157694520 156 D-ETKSLEEAQEWLKQfiqgPPEVIRALKKSVCSGRELYLEEA 197
Cdd:PRK09120 194 QlRARTRELAAKLLEK----NPVVLRAAKDGFKRVRELTWDQA 232
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
11-175 7.65e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 54.59  E-value: 7.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  11 ELENWTEGKGLIVRGAKNTFSSGSDLN----AVKSLGTPEdgmaVCMF--MQNTLTRFMR-LPLISVALVQGWALGGGAE 83
Cdd:PRK08258  55 ELVYADDVKAVVLTGAGGNFCSGGDVHeiigPLTKMDMPE----LLAFtrMTGDLVKAMRaCPQPIIAAVDGVCAGAGAI 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  84 FTTACDFRLMTPESKIRFVHKEMGIIPS-WGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqssDETKSLE 162
Cdd:PRK08258 131 LAMASDLRLGTPSAKTAFLFTRVGLAGAdMGACALLPRIIGQGRASELLYTGRSMSAEEGERWGFFNRLV---EPEELLA 207

                        170
                 ....*....|...
gi 157694520 163 EAQEWLKQFIQGP 175
Cdd:PRK08258 208 EAQALARRLAAGP 220
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
1-222 9.24e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 53.95  E-value: 9.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGtPEDGMAVCMFMQNTLT-----RFMRLPLIsvALVQG 75
Cdd:PRK07799  33 MLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKKP-PGDSFKDGSYDPSRIDallkgRRLTKPLI--AAVEG 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  76 WALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqss 155
Cdd:PRK07799 110 PAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAKEIGLIGHVV--- 186

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157694520 156 DETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLlgtvwGGPANLEAIAKKG 222
Cdd:PRK07799 187 PDGQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKI-----GIPVFLSEDAKEG 248
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 63-151 1.14e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 54.24  E-value: 1.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  63 MRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALK-VLSGALkLDSKN 141
Cdd:PRK08260 112 SLKPVI--AAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVGLQTALEwVYSGRV-FDAQE 188

                         90
                 ....*....|
gi 157694520 142 ALNIGMVEEV 151
Cdd:PRK08260 189 ALDGGLVRSV 198
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 21-183 2.48e-08

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 52.89  E-value: 2.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  21 LIVRGAKNTFSSGSDLNAVKSL------GTPEDGMAVCMFMQNtltrFMRLPLISVALVQGWALGGGAEFTTACDFRLMT 94
Cdd:PRK05674  54 LLLRGRGRHFSAGADLAWMQQSadldynTNLDDARELAELMYN----LYRLKIPTLAVVQGAAFGGALGLISCCDMAIGA 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  95 PESKIRFVHKEMGIIPSWGGTTrLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQ 173
Cdd:PRK05674 130 DDAQFCLSEVRIGLAPAVISPF-VVKAIGERAARRYALTAERFDGRRARELGLLAESYPAAE----LEaQVEAWIANLLL 204

                        170
                 ....*....|
gi 157694520 174 GPPEVIRALK 183
Cdd:PRK05674 205 NSPQALRASK 214
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
19-199 6.53e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 51.51  E-value: 6.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  19 KGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVcMFMQNTLTRFMRLPLI-------SVALVQGWALGGGAEFTTACDFR 91
Cdd:PRK09245  50 RAVILTGAGTAFSSGGNVKDMRARVGAFGGSPA-DIRQGYRHGIQRIPLAlynlevpVIAAVNGPAIGAGCDLACMCDIR 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  92 LMTPESKI--RFVhkEMGIIPSWGGTTRLVEIIG-SRQALKVLSGAlKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWL 168
Cdd:PRK09245 129 IASETARFaeSFV--KLGLIPGDGGAWLLPRIIGmARAAEMAFTGD-AIDAATALEWGLVSRVVPADQ---LLPAARALA 202

                        170       180       190
                 ....*....|....*....|....*....|.
gi 157694520 169 KQFIQGPPEVIRALKKSVCSGRELYLEEALQ 199
Cdd:PRK09245 203 ERIAANPPHALRLTKRLLREGQHASLDTLLE 233
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
1-185 7.54e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 51.50  E-value: 7.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV------KSLGTPEDGMAVCMFMQNTLTRfmrlPLISValVQ 74
Cdd:PRK06563  27 MLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVapklaaGGFPFPEGGIDPWGTVGRRLSK----PLVVA--VQ 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  75 GWALGGGAEFTTACDFRLMTpeSKIRFVHKEM--GIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVL 152
Cdd:PRK06563 101 GYCLTLGIELMLAADIVVAA--DNTRFAQLEVqrGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEALRLGLVQEVV 178

                        170       180       190
                 ....*....|....*....|....*....|....
gi 157694520 153 QSSDE-TKSLEEAQEWLKQfiqgPPEVIRALKKS 185
Cdd:PRK06563 179 PPGEQlERAIELAERIARA----APLGVQATLAS 208
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
59-183 1.09e-07

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 51.18  E-value: 1.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  59 LTRFMrlPLISVALVQGWALGGGAEFTTACDFRLMTPE-SKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 137
Cdd:PRK08321 130 LIRFM--PKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTY 207

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 157694520 138 DSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALK 183
Cdd:PRK08321 208 SAEEAHDMGAVNAVVPHAE----LEtEALEWAREINGKSPTAMRMLK 250
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 25-186 1.29e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 50.69  E-value: 1.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  25 GAKNTFSSGSDLNAVKSLG--TPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDF-------RLMTP 95
Cdd:PRK05995  56 GAGKAFCAGADLNWMKKMAgySDDENRADARRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIavaadhaVFCLS 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  96 ESKIrfvhkemGIIPSWGGTTrLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqSSDEtksLEEAQEWL-KQFIQG 174
Cdd:PRK05995 136 EVRL-------GLIPATISPY-VIRAMGERAARRYFLTAERFDAAEALRLGLVHEVV-PAEA---LDAKVDELlAALVAN 203

                        170
                 ....*....|..
gi 157694520 175 PPEVIRALKKSV 186
Cdd:PRK05995 204 SPQAVRAGKRLV 215
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 21-200 1.79e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 50.42  E-value: 1.79e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  21 LIVRGA-KNTFSSGSDLNAVKSLgTPEDGMAVcmfmqntLTRFMRL-------PLISVALVQGWALGGGAEFTTACDFRL 92
Cdd:PRK06143  55 LVLRGAgEKAFIGGADIKEMATL-DQASAEAF-------ISRLRDLcdavrhfPVPVIARIPGWCLGGGLELAAACDLRI 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  93 MT-------PESKIRfvhkemgiIPSWGGTTRLVEIIG-SRQALKVLSGALkLDSKNALNIGMVEEVLQSSDETKSLEEA 164
Cdd:PRK06143 127 AAhdaqfgmPEVRVG--------IPSVIHAALLPRLIGwARTRWLLLTGET-IDAAQALAWGLVDRVVPLAELDAAVERL 197

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 157694520 165 QEWLKQFiqgPPEVIRALKKSVCSGRELYLEEALQN 200
Cdd:PRK06143 198 AASLAGC---GPQALRQQKRLLREWEDMPLDVAIDD 230
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
1-166 7.29e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 45.39  E-value: 7.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENwtEGKGLIVRGAKNTFSSGSDLNAVKSLgTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGG 80
Cdd:PRK08150  30 LIAALRAAFARLPE--GVRAVVLHGEGDHFCAGLDLSELRER-DAGEGMHHSRRWHRVFDKIQYGRVPVIAALHGAVVGG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  81 GAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIG-SRQALKVLSGALkLDSKNALNIGMVEEVLQSSdetK 159
Cdd:PRK08150 107 GLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGvARMTDMMLTGRV-YDAQEGERLGLAQYLVPAG---E 182


                 ....*..
gi 157694520 160 SLEEAQE 166
Cdd:PRK08150 183 ALDKAME 189
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 1-148 1.28e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 44.82  E-value: 1.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNA------VKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQ 74
Cdd:PRK05864  38 VMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKSagvvphVEGLTRPTYALRSMELLDDVILALRRLHQPVIAAVN 117

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157694520  75 GWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLV-EIIGSRQALKVLSGALKLDSKNALNIGMV 148
Cdd:PRK05864 118 GPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASELGLSYLLpRAIGSSRAFEIMLTGRDVDAEEAERIGLV 192
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 25-156 3.05e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 43.93  E-value: 3.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  25 GAKNTFSSGSDLNAVKSLGtPEDGMA---VCMFMQN----TLTRF-----MRLPLIsvALVQGWALGGGAEFTTACDFRL 92
Cdd:PRK06210  58 GAGRGFCAGADMGELQTID-PSDGRRdtdVRPFVGNrrpdYQTRYhfltaLRKPVI--AAINGACAGIGLTHALMCDVRF 134

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157694520  93 MTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSD 156
Cdd:PRK06210 135 AADGAKFTTAFARRGLIAEHGISWILPRLVGHANALDLLLSARTFYAEEALRLGLVNRVVPPDE 198
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 58-135 3.29e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 43.75  E-value: 3.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  58 TLTRFMRLPLISVALVQGWALGGGAEFTTACDF-------RLMTPEskIRFvhkemGIIPSWGGTTRLVEIIGSRQALK- 129
Cdd:PRK08788 113 AFHRGFGAGAISIALVQGDALGGGFEAALSHHTiiaergaKMGFPE--ILF-----NLFPGMGAYSFLARRVGPKLAEEl 185


                 ....*.
gi 157694520 130 VLSGAL 135
Cdd:PRK08788 186 ILSGKL 191
PLN02921 PLN02921
naphthoate synthase
 64-185 4.22e-05

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 43.62  E-value: 4.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  64 RLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNAL 143
Cdd:PLN02921 159 RLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYTASEAL 238

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 157694520 144 NIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKS 185
Cdd:PLN02921 239 KMGLVNTVVPLDE----LEgETVKWCREILRNSPTAIRVLKSA 277
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
25-197 3.67e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 40.55  E-value: 3.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  25 GAKNTFSSGSDLN--AVKSLGTPEDGMAVCMFMQnTLTRFMRlPLISValVQGWALGGGAEFTTACDFRLMTPESKIRFV 102
Cdd:PRK06023  58 GTEGCFSAGNDMQdfLAAAMGGTSFGSEILDFLI-ALAEAEK-PIVSG--VDGLAIGIGTTIHLHCDLTFASPRSLFRTP 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520 103 HKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSD-ETKSLEEAQEWLKQfiqgPPEVIRA 181
Cdd:PRK06023 134 FVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEAAQEAGLIWKIVDEEAvEAETLKAAEELAAK----PPQALQI 209

                        170       180
                 ....*....|....*....|
gi 157694520 182 LKKSVCSGRELYL----EEA 197
Cdd:PRK06023 210 ARDLMRGPREDILaridEEA 229
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 13-128 6.41e-04

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 40.35  E-value: 6.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  13 ENWTEGKGL---IVRGAKNTFSSGSDLNAVKSLgTPEDGMAVCMFMQNTLTRFMRL------PliSVALVQGWALGGGAE 83
Cdd:PLN02851  79 ESWEENPDIgfvLMKGSGRAFCSGADVVSLYHL-INEGNVEECKLFFENLYKFVYLqgtylkP--NVAIMDGITMGCGAG 155

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 157694520  84 FTTACDFRLMTpeSKIRFVHKE--MGIIPSWGGT---TRLVEIIGSRQAL 128
Cdd:PLN02851 156 ISIPGMFRVVT--DKTVFAHPEvqMGFHPDAGASyylSRLPGYLGEYLAL 203
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
21-111 8.02e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 39.67  E-value: 8.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  21 LIVRGAKNTFSSGSDLNAVKSLgtPEDGMAVcMFMQNTL----TRFMRLPLISVALVQGWALGGGAEFTTACDfrLMTPE 96
Cdd:PRK07112  50 VVLEGLPEVFCFGADFSAIAEK--PDAGRAD-LIDAEPLydlwHRLATGPYVTIAHVRGKVNAGGIGFVAASD--IVIAD 124

                         90
                 ....*....|....*..
gi 157694520  97 SKIRFVHKEM--GIIPS 111
Cdd:PRK07112 125 ETAPFSLSELlfGLIPA 141
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
28-158 9.36e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 39.28  E-value: 9.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  28 NTFSSGSDLNAVKSLGTPEDGMAVcmFMQNTLTRFMR----LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVH 103
Cdd:PRK07827  61 GTFCAGADLSEAGGGGGDPYDAAV--ARAREMTALLRaiveLPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTE 138

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 157694520 104 KEMGIIPSWGGTTRLVEIIGSRQALKVLSGAlKLDSKNALNIGMVEEVLQSSDET 158
Cdd:PRK07827 139 ARIGVAPAIISLTLLPRLSPRAAARYYLTGE-KFGAAEAARIGLVTAAADDVDAA 192
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 12-181 1.22e-03

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 39.40  E-value: 1.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  12 LENWTE---GKGLIVRGAKNTFSSGSDLNAVKSLGTPEDG-MAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTA 87
Cdd:PLN02874  47 LEQWEKddsVELIIIKGAGRAFSAGGDLKMFYDGRESDDScLEVVYRMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVP 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  88 CDFRLMT-------PESKIRFvHKEMG---IIPSWGGttRLVEIIGsrqalkvLSGAlKLDSKNALNIGMVEEVLQSsde 157
Cdd:PLN02874 127 MKFRVVTektvfatPEASVGF-HTDCGfsyILSRLPG--HLGEYLA-------LTGA-RLNGKEMVACGLATHFVPS--- 192

                        170       180
                 ....*....|....*....|....
gi 157694520 158 tKSLEEAQEWLKQFIQGPPEVIRA 181
Cdd:PLN02874 193 -EKLPELEKRLLNLNSGDESAVQE 215
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 13-181 1.40e-03

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 39.28  E-value: 1.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  13 ENWTEGKGL---IVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMqNTLTRFMRL------PliSVALVQGWALGGGAE 83
Cdd:PLN02157  74 KNWEEDPNIgfvMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIREFF-SSLYSFIYLlgtylkP--HVAILNGVTMGGGTG 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  84 FTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGaLKLDSKNALNIGMVEEVLQsSDETKSLEE 163
Cdd:PLN02157 151 VSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTG-LKLSGAEMLACGLATHYIR-SEEIPVMEE 228

                        170
                 ....*....|....*...
gi 157694520 164 AqewLKQFIQGPPEVIRA 181
Cdd:PLN02157 229 Q---LKKLLTDDPSVVES 243
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
 16-158 2.40e-03

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 38.16  E-value: 2.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  16 TEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAV-CMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMT 94
Cdd:PLN02267  43 TPGSVLITTAEGKFFSNGFDLAWAQAAGSAPSRLHLmVAKLRPLVADLISLPMPTIAAVTGHASAAGFILALSHDYVLMR 122

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157694520  95 PESKIRFVhKEMGI---IPSWgGTTRLVEIIGSRQALK--VLSGAlKLDSKNALNIGMVEEVLQSSDET 158
Cdd:PLN02267 123 KDRGVLYM-SEVDIglpLPDY-FMALLRAKIGSPAARRdvLLRAA-KLTAEEAVEMGIVDSAHDSAEET 188
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 4-201 3.23e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 37.84  E-value: 3.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   4 QLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTpEDgmavcmfMQNT---LTRFMRLP-LISVALVQGWALG 79
Cdd:PRK06072  31 EFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEFAPDFA-ID-------LRETfypIIREIRFSdKIYISAINGVTAG 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  80 GGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGAlKLDSKNALNIGMVEevlQSSDetk 159
Cdd:PRK06072 103 ACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVLGG-EFTAEEAERWGLLK---ISED--- 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 157694520 160 SLEEAQEWLKQFIQGPPEVIRALKKSVcsGRELY--LEEALQNE 201
Cdd:PRK06072 176 PLSDAEEMANRISNGPFQSYIAAKRMI--NLVLYndLEEFLEYE 217
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 4-201 3.58e-03

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 37.64  E-value: 3.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   4 QLLEKVIELENWTEGKGLIVRGAKNTFSSGsdlnavkslGTPEDGMAVCM-FMQNTLTRFMRLPL---ISV-ALVQGWAL 78
Cdd:PRK07110  36 QLHEAFDTIAQDPRYKVVILTGYPNYFATG---------GTQEGLLSLQTgKGTFTEANLYSLALncpIPViAAMQGHAI 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  79 GGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqSSDET 158
Cdd:PRK07110 107 GGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAELKKRGVPFPVL-PRAEV 185

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 157694520 159 ksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNE 201
Cdd:PRK07110 186 --LEKALELARSLAEKPRHSLVLLKDHLVADRRRRLPEVIEQE 226
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 1-158 7.31e-03

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 37.00  E-value: 7.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV-KSLGTPEDGMAVCMFMQNTLTRFMRLPL--ISVALVQGWA 77
Cdd:PLN02988  37 MISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVvRDIEQGNWRLGANFFSDEYMLNYVMATYskAQVSILNGIV 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  78 LGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGAlKLDSKNALNIGMVEEVLQSSDE 157
Cdd:PLN02988 117 MGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGA-RLDGAEMLACGLATHFVPSTRL 195


                 .
gi 157694520 158 T 158
Cdd:PLN02988 196 T 196
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 1-204 9.57e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 36.26  E-value: 9.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520   1 MMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQ--NTLTRFM-RLPLISVALVQGWA 77
Cdd:PRK07260  30 MCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSLVKIAElvNEISFAIkQLPKPVIMCVDGAV 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157694520  78 LGGGAEFTTACDFRLMTpeSKIRFVHK--EMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSS 155
Cdd:PRK07260 110 AGAAANMAVAADFCIAS--TKTKFIQAfvGVGLAPDAGGLFLLTRAIGLNRATHLAMTGEALTAEKALEYGFVYRVAESE 187

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 157694520 156 DETKSLEEAqewLKQFIQGPPEVIRALK----KSVCSGRELYLEEALQNERDL 204
Cdd:PRK07260 188 KLEKTCEQL---LKKLRRGSSNSYAAIKslvwESFFKGWEDYAKLELALQESL 237
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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