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Conserved domains on  [gi|157823667|ref|NP_001101117|]
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U3 small nucleolar RNA-associated protein 15 homolog [Rattus norvegicus]

Protein Classification

U3 small nucleolar RNA-associated protein 15( domain architecture ID 11456900)

U3 small nucleolar RNA-associated protein 15 is involved in nucleolar processing of pre-18S ribosomal RNA

Gene Ontology:  GO:0042274|GO:0006364|GO:0003723

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UTP15_C pfam09384
UTP15 C terminal; U3 snoRNA is ubiquitous in eukaryotes and is required for nucleolar ...
 344-490 1.58e-62

UTP15 C terminal; U3 snoRNA is ubiquitous in eukaryotes and is required for nucleolar processing of pre-18S ribosomal RNA. It is a component of the ribosomal small subunit (SSU) processome. UTP15 is needed for optimal pre-ribosomal RNA transcription by RNA polymerase I, together with a subset of U3 proteins required for transcription (t-UTPs). This entry represents the C terminal of UTP15, and is found adjacent to WD40 repeats (pfam00400).


:

Pssm-ID: 462782  Cd Length: 146  Bit Score: 201.17  E-value: 1.58e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  344 YTKQRDDIVVTRPAKKHLEWYDRDLKSFRISKALDRVLEPNcvIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLN 423
Cdd:pfam09384   2 YKGEGDDIVVEGPKKKKLKKYDKLLRKFRYSKALDAVLEPG--VKSPEVTVAVLEELRHRGALRAALAGRDEESLEPLLK 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157823667  424 FLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDML 490
Cdd:pfam09384  80 FLIKHITDPRFTRLLVDVANVVLDIYGSVLGQSPELDKLFRRLRRKVREEIELQKELLELKGMLDML 146
WD40 COG2319
WD40 repeat [General function prediction only];
39-307 1.71e-57

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 196.67  E-value: 1.71e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  39 GAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQF 118
Cdd:COG2319   79 AAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTL 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 119 EGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASklnPD--LFVTGSYDHTVKMFDART 196
Cdd:COG2319  159 TGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFS---PDgkLLASGSADGTVRLWDLAT 235

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 197 NKNVLCVE-HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKI 274
Cdd:COG2319  236 GKLLRTLTgHSGSVRSVAFSPDGRLLASGSAdGTVRLWD-LATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRL 314

                        250       260       270
                 ....*....|....*....|....*....|....
gi 157823667 275 YSTTSYKVVHSFD-YAASILSLALSHQDETVVVG 307
Cdd:COG2319  315 WDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASG 348
 
Name Accession Description Interval E-value
UTP15_C pfam09384
UTP15 C terminal; U3 snoRNA is ubiquitous in eukaryotes and is required for nucleolar ...
 344-490 1.58e-62

UTP15 C terminal; U3 snoRNA is ubiquitous in eukaryotes and is required for nucleolar processing of pre-18S ribosomal RNA. It is a component of the ribosomal small subunit (SSU) processome. UTP15 is needed for optimal pre-ribosomal RNA transcription by RNA polymerase I, together with a subset of U3 proteins required for transcription (t-UTPs). This entry represents the C terminal of UTP15, and is found adjacent to WD40 repeats (pfam00400).


Pssm-ID: 462782  Cd Length: 146  Bit Score: 201.17  E-value: 1.58e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  344 YTKQRDDIVVTRPAKKHLEWYDRDLKSFRISKALDRVLEPNcvIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLN 423
Cdd:pfam09384   2 YKGEGDDIVVEGPKKKKLKKYDKLLRKFRYSKALDAVLEPG--VKSPEVTVAVLEELRHRGALRAALAGRDEESLEPLLK 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157823667  424 FLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDML 490
Cdd:pfam09384  80 FLIKHITDPRFTRLLVDVANVVLDIYGSVLGQSPELDKLFRRLRRKVREEIELQKELLELKGMLDML 146
WD40 COG2319
WD40 repeat [General function prediction only];
39-307 1.71e-57

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 196.67  E-value: 1.71e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  39 GAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQF 118
Cdd:COG2319   79 AAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTL 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 119 EGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASklnPD--LFVTGSYDHTVKMFDART 196
Cdd:COG2319  159 TGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFS---PDgkLLASGSADGTVRLWDLAT 235

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 197 NKNVLCVE-HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKI 274
Cdd:COG2319  236 GKLLRTLTgHSGSVRSVAFSPDGRLLASGSAdGTVRLWD-LATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRL 314

                        250       260       270
                 ....*....|....*....|....*....|....
gi 157823667 275 YSTTSYKVVHSFD-YAASILSLALSHQDETVVVG 307
Cdd:COG2319  315 WDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASG 348
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 39-298 2.01e-48

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 169.05  E-value: 2.01e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  39 GAVSKVDFSPQPpyNYAVTASS--RIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLR 116
Cdd:cd00200   10 GGVTCVAFSPDG--KLLATGSGdgTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 117 QFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKlNPDLFVTGSYDHTVKMFDART 196
Cdd:cd00200   88 TLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSP-DGTFVASSSQDGTIKLWDLRT 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 197 NKnvlCVE----HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRK 271
Cdd:cd00200  167 GK---CVAtltgHTGEVNSVAFSPDGEKLLSSSSdGTIKLWD-LSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGT 242

                        250       260
                 ....*....|....*....|....*...
gi 157823667 272 VKIYSTTSYKVVHSFD-YAASILSLALS 298
Cdd:cd00200  243 IRVWDLRTGECVQTLSgHTNSVTSLAWS 270
PTZ00421 PTZ00421
coronin; Provisional
 91-236 1.02e-08

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 57.60  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  91 DGQLLVAGSEDGVVQLFDI-------SGRAPLRQFEGHTKAVHTVDFTADKYHVVSGAD-DYTVKLWDIPNSKEILTFKE 162
Cdd:PTZ00421  87 DPQKLFTASEDGTIMGWGIpeegltqNISDPIVHLQGHTKKVGIVSFHPSAMNVLASAGaDMVVNVWDVERGKAVEVIKC 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 163 HSDYVrCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVES--VLLFPSGGLLVSAG-----GRYVKVWDML 235
Cdd:PTZ00421 167 HSDQI-TSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSqrCLWAKRKDLIITLGcsksqQRQIMLWDTR 245


                 .
gi 157823667 236 K 236
Cdd:PTZ00421 246 K 246
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 114-150 1.40e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 47.69  E-value: 1.40e-07
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 157823667   114 PLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWD 150
Cdd:smart00320   4 LLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
114-150 2.44e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 46.95  E-value: 2.44e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 157823667  114 PLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWD 150
Cdd:pfam00400   3 LLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
UTP15_C pfam09384
UTP15 C terminal; U3 snoRNA is ubiquitous in eukaryotes and is required for nucleolar ...
 344-490 1.58e-62

UTP15 C terminal; U3 snoRNA is ubiquitous in eukaryotes and is required for nucleolar processing of pre-18S ribosomal RNA. It is a component of the ribosomal small subunit (SSU) processome. UTP15 is needed for optimal pre-ribosomal RNA transcription by RNA polymerase I, together with a subset of U3 proteins required for transcription (t-UTPs). This entry represents the C terminal of UTP15, and is found adjacent to WD40 repeats (pfam00400).


Pssm-ID: 462782  Cd Length: 146  Bit Score: 201.17  E-value: 1.58e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  344 YTKQRDDIVVTRPAKKHLEWYDRDLKSFRISKALDRVLEPNcvIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLN 423
Cdd:pfam09384   2 YKGEGDDIVVEGPKKKKLKKYDKLLRKFRYSKALDAVLEPG--VKSPEVTVAVLEELRHRGALRAALAGRDEESLEPLLK 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157823667  424 FLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDML 490
Cdd:pfam09384  80 FLIKHITDPRFTRLLVDVANVVLDIYGSVLGQSPELDKLFRRLRRKVREEIELQKELLELKGMLDML 146
WD40 COG2319
WD40 repeat [General function prediction only];
39-307 1.71e-57

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 196.67  E-value: 1.71e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  39 GAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQF 118
Cdd:COG2319   79 AAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTL 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 119 EGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASklnPD--LFVTGSYDHTVKMFDART 196
Cdd:COG2319  159 TGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFS---PDgkLLASGSADGTVRLWDLAT 235

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 197 NKNVLCVE-HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKI 274
Cdd:COG2319  236 GKLLRTLTgHSGSVRSVAFSPDGRLLASGSAdGTVRLWD-LATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRL 314

                        250       260       270
                 ....*....|....*....|....*....|....
gi 157823667 275 YSTTSYKVVHSFD-YAASILSLALSHQDETVVVG 307
Cdd:COG2319  315 WDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASG 348
WD40 COG2319
WD40 repeat [General function prediction only];
39-307 9.95e-56

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 192.05  E-value: 9.95e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  39 GAVSKVDFSPQPpyNYAVTASS--RIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLR 116
Cdd:COG2319  121 GAVRSVAFSPDG--KTLASGSAdgTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLR 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 117 QFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCgCAskLNPD--LFVTGSYDHTVKMFDA 194
Cdd:COG2319  199 TLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRS-VA--FSPDgrLLASGSADGTVRLWDL 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 195 RTNKNVLCVE-HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKV 272
Cdd:COG2319  276 ATGELLRTLTgHSGGVNSVAFSPDGKLLASGSDdGTVRLWD-LATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTV 354

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 157823667 273 KIYSTTSYKVVHSF-DYAASILSLALSHQDETVVVG 307
Cdd:COG2319  355 RLWDLATGELLRTLtGHTGAVTSVAFSPDGRTLASG 390
WD40 COG2319
WD40 repeat [General function prediction only];
38-315 1.02e-51

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 181.26  E-value: 1.02e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  38 FGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQ 117
Cdd:COG2319   36 AAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRT 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 118 FEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCgCAskLNPD--LFVTGSYDHTVKMFDAR 195
Cdd:COG2319  116 LTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTS-VA--FSPDgkLLASGSDDGTVRLWDLA 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 196 TNKNVLCVE-HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVK 273
Cdd:COG2319  193 TGKLLRTLTgHTGAVRSVAFSPDGKLLASGSAdGTVRLWD-LATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVR 271

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 157823667 274 IYSTTSYKVVHSFD-YAASILSLALSHQDETVVVGMTNGILSV 315
Cdd:COG2319  272 LWDLATGELLRTLTgHSGGVNSVAFSPDGKLLASGSDDGTVRL 314
WD40 COG2319
WD40 repeat [General function prediction only];
39-279 1.79e-51

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 180.88  E-value: 1.79e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  39 GAVSKVDFSPQPpyNYAVTASS--RIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLR 116
Cdd:COG2319  163 GAVTSVAFSPDG--KLLASGSDdgTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLR 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 117 QFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASklnPD--LFVTGSYDHTVKMFDA 194
Cdd:COG2319  241 TLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFS---PDgkLLASGSDDGTVRLWDL 317

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 195 RTNKNVLCVE-HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKV 272
Cdd:COG2319  318 ATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDdGTVRLWD-LATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTV 396


                 ....*..
gi 157823667 273 KIYSTTS 279
Cdd:COG2319  397 RLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 39-298 2.01e-48

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 169.05  E-value: 2.01e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  39 GAVSKVDFSPQPpyNYAVTASS--RIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLR 116
Cdd:cd00200   10 GGVTCVAFSPDG--KLLATGSGdgTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 117 QFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKlNPDLFVTGSYDHTVKMFDART 196
Cdd:cd00200   88 TLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSP-DGTFVASSSQDGTIKLWDLRT 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 197 NKnvlCVE----HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRK 271
Cdd:cd00200  167 GK---CVAtltgHTGEVNSVAFSPDGEKLLSSSSdGTIKLWD-LSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGT 242

                        250       260
                 ....*....|....*....|....*...
gi 157823667 272 VKIYSTTSYKVVHSFD-YAASILSLALS 298
Cdd:cd00200  243 IRVWDLRTGECVQTLSgHTNSVTSLAWS 270
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 72-315 5.68e-48

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 167.90  E-value: 5.68e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  72 PVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDI 151
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 152 PNSKEILTFKEHSDYVRCgCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVE-HGQPVESVLLFPSGGLLVSAGG-RYV 229
Cdd:cd00200   81 ETGECVRTLTGHTSYVSS-VAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRgHTDWVNSVAFSPDGTFVASSSQdGTI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 230 KVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKIYSTTSYKVVHSFDY-AASILSLALSHQDETVVVGM 308
Cdd:cd00200  160 KLWD-LRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLASGS 238


                 ....*..
gi 157823667 309 TNGILSV 315
Cdd:cd00200  239 EDGTIRV 245
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 39-276 1.89e-46

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 164.05  E-value: 1.89e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  39 GAVSKVDFSPQppYNYAVTASS----RIHIYGrySQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAP 114
Cdd:cd00200   52 GPVRDVAASAD--GTYLASGSSdktiRLWDLE--TGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKC 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 115 LRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKlNPDLFVTGSYDHTVKMFDA 194
Cdd:cd00200  128 LTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSP-DGEKLLSSSSDGTIKLWDL 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 195 RTNKNV-LCVEHGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKV 272
Cdd:cd00200  207 STGKCLgTLRGHENGVNSVAFSPDGYLLASGSEdGTIRVWD-LRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTI 285


                 ....
gi 157823667 273 KIYS 276
Cdd:cd00200  286 RIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
45-315 8.64e-41

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 151.60  E-value: 8.64e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  45 DFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKA 124
Cdd:COG2319    1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 125 VHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASklnPD--LFVTGSYDHTVKMFDARTNKNVLC 202
Cdd:COG2319   81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFS---PDgkTLASGSADGTVRLWDLATGKLLRT 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 203 VE-HGQPVESVLLFPSGGLLVSAGG-RYVKVWDmLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKIYSTTSY 280
Cdd:COG2319  158 LTgHSGAVTSVAFSPDGKLLASGSDdGTVRLWD-LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATG 236

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 157823667 281 KVVHSFD-YAASILSLALSHQDETVVVGMTNGILSV 315
Cdd:COG2319  237 KLLRTLTgHSGSVRSVAFSPDGRLLASGSADGTVRL 272
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 26-193 6.80e-28

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 113.20  E-value: 6.80e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  26 WNNyKTPVQIKEF----GAVSKVDFSPQPPYnyaVTASSR---IHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAG 98
Cdd:cd00200  120 WDV-ETGKCLTTLrghtDWVNSVAFSPDGTF---VASSSQdgtIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSS 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  99 SEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPD 178
Cdd:cd00200  196 SSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKR 275

                        170
                 ....*....|....*
gi 157823667 179 LfVTGSYDHTVKMFD 193
Cdd:cd00200  276 L-ASGSADGTIRIWD 289
PTZ00421 PTZ00421
coronin; Provisional
 91-236 1.02e-08

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 57.60  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  91 DGQLLVAGSEDGVVQLFDI-------SGRAPLRQFEGHTKAVHTVDFTADKYHVVSGAD-DYTVKLWDIPNSKEILTFKE 162
Cdd:PTZ00421  87 DPQKLFTASEDGTIMGWGIpeegltqNISDPIVHLQGHTKKVGIVSFHPSAMNVLASAGaDMVVNVWDVERGKAVEVIKC 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 163 HSDYVrCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVES--VLLFPSGGLLVSAG-----GRYVKVWDML 235
Cdd:PTZ00421 167 HSDQI-TSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSqrCLWAKRKDLIITLGcsksqQRQIMLWDTR 245


                 .
gi 157823667 236 K 236
Cdd:PTZ00421 246 K 246
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 85-318 8.36e-08

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 55.09  E-value: 8.36e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  85 CA-TFRQDGQLLVAGSEDGVVQLFDIS-----GRA---PLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSK 155
Cdd:PLN00181 487 CAiGFDRDGEFFATAGVNKKIKIFECEsiikdGRDihyPVVELASRSKLSGICWNSYIKSQVASSNFEGVVQVWDVARSQ 566

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 156 EILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDA---------RTNKNVLCVEhgqpvesvllFPSG---GLLVS 223
Cdd:PLN00181 567 LVTEMKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWSInqgvsigtiKTKANICCVQ----------FPSEsgrSLAFG 636

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 224 AGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQrLLSGSLDRKVKIY------STTSYKVVHSFDYAASILS-LA 296
Cdd:PLN00181 637 SADHKVYYYDLRNPKLPLCTMIGHSKTVSYVRFVDSST-LVSSSTDNTLKLWdlsmsiSGINETPLHSFMGHTNVKNfVG 715

                        250       260
                 ....*....|....*....|..
gi 157823667 297 LSHQDETVVVGMTNGILSVKHR 318
Cdd:PLN00181 716 LSVSDGYIATGSETNEVFVYHK 737
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 114-150 1.40e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 47.69  E-value: 1.40e-07
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 157823667   114 PLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWD 150
Cdd:smart00320   4 LLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 238-276 1.58e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 47.69  E-value: 1.58e-07
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 157823667   238 GQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKIYS 276
Cdd:smart00320   2 GELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
114-150 2.44e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 46.95  E-value: 2.44e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 157823667  114 PLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWD 150
Cdd:pfam00400   3 LLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
238-276 4.39e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 46.18  E-value: 4.39e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 157823667  238 GQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKIYS 276
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 153-193 1.04e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.60  E-value: 1.04e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 157823667   153 NSKEILTFKEHSDYVRCGCASKlNPDLFVTGSYDHTVKMFD 193
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 69-108 1.22e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.60  E-value: 1.22e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 157823667    69 SQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFD 108
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
154-193 1.67e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 38.87  E-value: 1.67e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 157823667  154 SKEILTFKEHSDYVRCgCASKLNPDLFVTGSYDHTVKMFD 193
Cdd:pfam00400   1 GKLLKTLEGHTGSVTS-LAFSPDGKLLASGSDDGTVKVWD 39
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
179-306 1.37e-03

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 40.45  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667 179 LFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLL--VSAGGRYVKVWDmLKGGQLLVSLKNhHKTVTCLCL 256
Cdd:COG3391   82 LYVANSGSGRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLyvADSGNGRVSVID-TATGKVVATIPV-GAGPHGIAV 159

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 157823667 257 SSSGQRLLSGSLDRK-----VKIYSTTSYKVVHSFDYAASILSLALSHQDETVVV 306
Cdd:COG3391  160 DPDGKRLYVANSGSNtvsviVSVIDTATGKVVATIPVGGGPVGVAVSPDGRRLYV 214
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
55-197 2.08e-03

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 40.06  E-value: 2.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823667  55 AVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHtKAVHTVDFTAD- 133
Cdd:COG3391   85 ANSGSGRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVG-AGPHGIAVDPDg 163

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157823667 134 KYHVVSGADDYT----VKLWDIPNSKEILTFKEHSDyvrcGCASKLNPD---LFVTGSY-------DHTVKMFDARTN 197
Cdd:COG3391  164 KRLYVANSGSNTvsviVSVIDTATGKVVATIPVGGG----PVGVAVSPDgrrLYVANRGsntsnggSNTVSVIDLATL 237
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 230-290 2.11e-03

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 37.26  E-value: 2.11e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157823667  230 KVWDmlkggqllVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKIYSTTSYKVVHSFDYAA 290
Cdd:pfam12894  28 RVWT--------LSPDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGS 80
WD40 pfam00400
WD domain, G-beta repeat;
71-108 2.33e-03

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 35.78  E-value: 2.33e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 157823667   71 EPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFD 108
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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