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Conserved domains on  [gi|189095241|ref|NP_001121142|]
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potassium voltage-gated channel subfamily E member 1 [Homo sapiens]

Protein Classification

ISK_Channel domain-containing protein( domain architecture ID 10489118)

ISK_Channel domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ISK_Channel pfam02060
Slow voltage-gated potassium channel;
1-126 1.48e-94

Slow voltage-gated potassium channel;


:

Pssm-ID: 460432  Cd Length: 126  Bit Score: 267.78  E-value: 1.48e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095241    1 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNV 80
Cdd:pfam02060   1 MILSNSTAVNPFLTKLWQETVQQGNNSSGLARRSPLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNV 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 189095241   81 YIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETK 126
Cdd:pfam02060  81 YIESDTWQEKDKAYFQARVLESYKACYVIENQLAVEQPNTYLPEEK 126
 
Name Accession Description Interval E-value
ISK_Channel pfam02060
Slow voltage-gated potassium channel;
1-126 1.48e-94

Slow voltage-gated potassium channel;


Pssm-ID: 460432  Cd Length: 126  Bit Score: 267.78  E-value: 1.48e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095241    1 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNV 80
Cdd:pfam02060   1 MILSNSTAVNPFLTKLWQETVQQGNNSSGLARRSPLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNV 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 189095241   81 YIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETK 126
Cdd:pfam02060  81 YIESDTWQEKDKAYFQARVLESYKACYVIENQLAVEQPNTYLPEEK 126
 
Name Accession Description Interval E-value
ISK_Channel pfam02060
Slow voltage-gated potassium channel;
1-126 1.48e-94

Slow voltage-gated potassium channel;


Pssm-ID: 460432  Cd Length: 126  Bit Score: 267.78  E-value: 1.48e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189095241    1 MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNV 80
Cdd:pfam02060   1 MILSNSTAVNPFLTKLWQETVQQGNNSSGLARRSPLRDDSKLEALYILMVLGFFGFFTLGIMLSYIRSKKLEHSHDPFNV 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 189095241   81 YIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETK 126
Cdd:pfam02060  81 YIESDTWQEKDKAYFQARVLESYKACYVIENQLAVEQPNTYLPEEK 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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