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Conserved domains on  [gi|192447417|ref|NP_001122245|]
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alpha(1,3)fucosyltransferase gene 2 [Danio rerio]

Protein Classification

glycosyltransferase family 10 fucosyltransferase( domain architecture ID 11246723)

glycosyltransferase family 10 fucosyltransferase transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage

CAZY:  GT10
EC:  2.4.1.-
Gene Ontology:  GO:0006486|GO:0008417
PubMed:  9451017|9334165

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_10 pfam00852
Glycosyltransferase family 10 (fucosyltransferase) C-term; This is the C-terminal domain of a ...
 213-387 3.83e-80

Glycosyltransferase family 10 (fucosyltransferase) C-term; This is the C-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The C-terminal domain is the likely binding-region for ADP (manuscript in publication).


:

Pssm-ID: 459962  Cd Length: 176  Bit Score: 243.62  E-value: 3.83e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417  213 IPKKDKLVCWIVSNFQEHHKRTHFYYEFAKHINVETYGGHFNN-RINSEDYGNVVSSCKFYLSFENSIHRDYFTEKLFNP 291
Cdd:pfam00852   1 LPKKTKLVAWVVSNCNTSSARVKYYNELQKHIEVDVYGRCGNLkPLSPGCYLMLISSYKFYLAFENSICKDYITEKLWNA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417  292 LALGTVPVVIGPPRYNYEEFIPRDAFIHVDDFPSPKELADHLISLDQNEEQYKQFFNWRKLY-VSKSTSFglEHSCKICD 370
Cdd:pfam00852  81 LLRGAVPVVLGPPRANYERFAPPDSFIHVDDFPSPKELAEYLLYLDKNDTLYLRYFWWRKHYrVIPLSSW--EPFCDLCQ 158

                         170
                  ....*....|....*...
gi 192447417  371 YLKR-NKHYIAVTDLKGW 387
Cdd:pfam00852 159 KLHRdSRRYKTYPDLAKW 176
Glyco_tran_10_N pfam17039
Fucosyltransferase, N-terminal; This is the N-terminal domain of a family of ...
 98-199 5.26e-41

Fucosyltransferase, N-terminal; This is the N-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The N-terminal domain is the likely binding-region for the fucose-like substrate (manuscript in publication).


:

Pssm-ID: 465336  Cd Length: 109  Bit Score: 140.52  E-value: 5.26e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417   98 IVLIWMAPFGVRFDLKDCGSEYNIHGCQLTYDRSMIQQAHGVMFHHRDMSADF---PQPPRPAFQKWIWWNMESPSHCNQ 174
Cdd:pfam17039   5 LILLWTWPFGDSFDLLGCSDLFGITGCRLTYDRSLYPEADAVVFHHRDISLDLkdlPYSPRPPGQRWVWFNLESPTNTPR 84

                          90       100
                  ....*....|....*....|....*
gi 192447417  175 NDFLNDRFNVTSSYNRNSDIPVPYG 199
Cdd:pfam17039  85 LPGLDNFFNWTMTYRRDSDIFTPYG 109
 
Name Accession Description Interval E-value
Glyco_transf_10 pfam00852
Glycosyltransferase family 10 (fucosyltransferase) C-term; This is the C-terminal domain of a ...
 213-387 3.83e-80

Glycosyltransferase family 10 (fucosyltransferase) C-term; This is the C-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The C-terminal domain is the likely binding-region for ADP (manuscript in publication).


Pssm-ID: 459962  Cd Length: 176  Bit Score: 243.62  E-value: 3.83e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417  213 IPKKDKLVCWIVSNFQEHHKRTHFYYEFAKHINVETYGGHFNN-RINSEDYGNVVSSCKFYLSFENSIHRDYFTEKLFNP 291
Cdd:pfam00852   1 LPKKTKLVAWVVSNCNTSSARVKYYNELQKHIEVDVYGRCGNLkPLSPGCYLMLISSYKFYLAFENSICKDYITEKLWNA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417  292 LALGTVPVVIGPPRYNYEEFIPRDAFIHVDDFPSPKELADHLISLDQNEEQYKQFFNWRKLY-VSKSTSFglEHSCKICD 370
Cdd:pfam00852  81 LLRGAVPVVLGPPRANYERFAPPDSFIHVDDFPSPKELAEYLLYLDKNDTLYLRYFWWRKHYrVIPLSSW--EPFCDLCQ 158

                         170
                  ....*....|....*...
gi 192447417  371 YLKR-NKHYIAVTDLKGW 387
Cdd:pfam00852 159 KLHRdSRRYKTYPDLAKW 176
Glyco_tran_10_N pfam17039
Fucosyltransferase, N-terminal; This is the N-terminal domain of a family of ...
 98-199 5.26e-41

Fucosyltransferase, N-terminal; This is the N-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The N-terminal domain is the likely binding-region for the fucose-like substrate (manuscript in publication).


Pssm-ID: 465336  Cd Length: 109  Bit Score: 140.52  E-value: 5.26e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417   98 IVLIWMAPFGVRFDLKDCGSEYNIHGCQLTYDRSMIQQAHGVMFHHRDMSADF---PQPPRPAFQKWIWWNMESPSHCNQ 174
Cdd:pfam17039   5 LILLWTWPFGDSFDLLGCSDLFGITGCRLTYDRSLYPEADAVVFHHRDISLDLkdlPYSPRPPGQRWVWFNLESPTNTPR 84

                          90       100
                  ....*....|....*....|....*
gi 192447417  175 NDFLNDRFNVTSSYNRNSDIPVPYG 199
Cdd:pfam17039  85 LPGLDNFFNWTMTYRRDSDIFTPYG 109
 
Name Accession Description Interval E-value
Glyco_transf_10 pfam00852
Glycosyltransferase family 10 (fucosyltransferase) C-term; This is the C-terminal domain of a ...
 213-387 3.83e-80

Glycosyltransferase family 10 (fucosyltransferase) C-term; This is the C-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The C-terminal domain is the likely binding-region for ADP (manuscript in publication).


Pssm-ID: 459962  Cd Length: 176  Bit Score: 243.62  E-value: 3.83e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417  213 IPKKDKLVCWIVSNFQEHHKRTHFYYEFAKHINVETYGGHFNN-RINSEDYGNVVSSCKFYLSFENSIHRDYFTEKLFNP 291
Cdd:pfam00852   1 LPKKTKLVAWVVSNCNTSSARVKYYNELQKHIEVDVYGRCGNLkPLSPGCYLMLISSYKFYLAFENSICKDYITEKLWNA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417  292 LALGTVPVVIGPPRYNYEEFIPRDAFIHVDDFPSPKELADHLISLDQNEEQYKQFFNWRKLY-VSKSTSFglEHSCKICD 370
Cdd:pfam00852  81 LLRGAVPVVLGPPRANYERFAPPDSFIHVDDFPSPKELAEYLLYLDKNDTLYLRYFWWRKHYrVIPLSSW--EPFCDLCQ 158

                         170
                  ....*....|....*...
gi 192447417  371 YLKR-NKHYIAVTDLKGW 387
Cdd:pfam00852 159 KLHRdSRRYKTYPDLAKW 176
Glyco_tran_10_N pfam17039
Fucosyltransferase, N-terminal; This is the N-terminal domain of a family of ...
 98-199 5.26e-41

Fucosyltransferase, N-terminal; This is the N-terminal domain of a family of fucosyltransferases. This enzyme transfers fucose from GDP-Fucose to GlcNAc in an alpha1,3 linkage. This family is known as glycosyltransferase family 10. The N-terminal domain is the likely binding-region for the fucose-like substrate (manuscript in publication).


Pssm-ID: 465336  Cd Length: 109  Bit Score: 140.52  E-value: 5.26e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 192447417   98 IVLIWMAPFGVRFDLKDCGSEYNIHGCQLTYDRSMIQQAHGVMFHHRDMSADF---PQPPRPAFQKWIWWNMESPSHCNQ 174
Cdd:pfam17039   5 LILLWTWPFGDSFDLLGCSDLFGITGCRLTYDRSLYPEADAVVFHHRDISLDLkdlPYSPRPPGQRWVWFNLESPTNTPR 84

                          90       100
                  ....*....|....*....|....*
gi 192447417  175 NDFLNDRFNVTSSYNRNSDIPVPYG 199
Cdd:pfam17039  85 LPGLDNFFNWTMTYRRDSDIFTPYG 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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