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Conserved domains on  [gi|213417737|ref|NP_001132982|]
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ethylmalonyl-CoA decarboxylase isoform 5 [Homo sapiens]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to human ethylmalonyl-CoA decarboxylase that decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016829
PubMed:  12467702|22016388

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 61-300 8.78e-61

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 193.84  E-value: 8.78e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTL 140
Cdd:COG1024    6 EGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRLF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 141 TRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDS 220
Cdd:COG1024   86 RALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 221 KNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 300
Cdd:COG1024  166 EEALELGLVNRVV-PDDEL--LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 61-300 8.78e-61

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 193.84  E-value: 8.78e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTL 140
Cdd:COG1024    6 EGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRLF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 141 TRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDS 220
Cdd:COG1024   86 RALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 221 KNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 300
Cdd:COG1024  166 EEALELGLVNRVV-PDDEL--LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 60-251 1.09e-52

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 171.20  E-value: 1.09e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  60 EDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMF-MQN 138
Cdd:cd06558    5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIReLQE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 139 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 218
Cdd:cd06558   85 LLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164

                        170       180       190
                 ....*....|....*....|....*....|...
gi 213417737 219 DSKNALNIGMVEEVLqssDETKSLEEAQEWLKQ 251
Cdd:cd06558  165 SAEEALELGLVDEVV---PDEELLAAALELARR 194
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 62-287 6.60e-29

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 110.91  E-value: 6.60e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737   62 NGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFmQNTLT 141
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENV-LDLWT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  142 RFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSK 221
Cdd:pfam00378  83 LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 213417737  222 NALNIGMVEEVLQssdETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 287
Cdd:pfam00378 163 EALKWGLVDKVVP---EDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY 225
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 55-291 2.21e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 109.72  E-value: 2.21e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  55 IDLQKEDnGIGILTLNNPSrMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCM 134
Cdd:PRK07658   4 LSVRVED-HVAVITLNHPP-ANALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSVTEAEQATELAQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 135 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 214
Cdd:PRK07658  82 LGQVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLT 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 213417737 215 ALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWG 291
Cdd:PRK07658 162 SEPITGAEALKWGLVNGVF---PEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFT 235
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 62-234 3.12e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 67.17  E-value: 3.12e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737   62 NGIGILTLNNP-SRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAK-NTFSSGSDLNAVKSLGTPEDGMAVCMFMQNT 139
Cdd:TIGR02441  21 GDVAVVKIDSPnSKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKpGSFVAGADIQMIAACKTAQEVTQLSQEGQEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  140 LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGALK 217
Cdd:TIGR02441 101 FERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180

                         170
                  ....*....|....*..
gi 213417737  218 LDSKNALNIGMVEEVLQ 234
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVD 197
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 61-300 8.78e-61

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 193.84  E-value: 8.78e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTL 140
Cdd:COG1024    6 EGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARGLQRLF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 141 TRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDS 220
Cdd:COG1024   86 RALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 221 KNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLEAIA 300
Cdd:COG1024  166 EEALELGLVNRVV-PDDEL--LAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIA 242
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 60-251 1.09e-52

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 171.20  E-value: 1.09e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  60 EDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMF-MQN 138
Cdd:cd06558    5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIReLQE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 139 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 218
Cdd:cd06558   85 LLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164

                        170       180       190
                 ....*....|....*....|....*....|...
gi 213417737 219 DSKNALNIGMVEEVLqssDETKSLEEAQEWLKQ 251
Cdd:cd06558  165 SAEEALELGLVDEVV---PDEELLAAALELARR 194
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 62-287 6.60e-29

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 110.91  E-value: 6.60e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737   62 NGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFmQNTLT 141
Cdd:pfam00378   4 AGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENV-LDLWT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  142 RFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDSK 221
Cdd:pfam00378  83 LLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQ 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 213417737  222 NALNIGMVEEVLQssdETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 287
Cdd:pfam00378 163 EALKWGLVDKVVP---EDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY 225
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 55-291 2.21e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 109.72  E-value: 2.21e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  55 IDLQKEDnGIGILTLNNPSrMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCM 134
Cdd:PRK07658   4 LSVRVED-HVAVITLNHPP-ANALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSVTEAEQATELAQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 135 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 214
Cdd:PRK07658  82 LGQVTFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLT 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 213417737 215 ALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWG 291
Cdd:PRK07658 162 SEPITGAEALKWGLVNGVF---PEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFT 235
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 49-291 8.53e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 108.54  E-value: 8.53e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  49 QFPGGSIDLQKE-DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTP 126
Cdd:PRK06144   2 AMTTSTDELLLEvRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAgDKAFVAGTDIAQFRAFSTA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 127 EDGMAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRF-VHKEMGIIPSWGGTTRLVEIIGS 205
Cdd:PRK06144  82 EDAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFpIARTLGNCLSMSNLARLVALLGA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 206 RQALKVLSGALKLDSKNALNIGMVEEVLQssDETKSlEEAQEWLKQFIQGPPEVIRALKKSVcsgRELyLEEALQNERDL 285
Cdd:PRK06144 162 ARVKDMLFTARLLEAEEALAAGLVNEVVE--DAALD-ARADALAELLAAHAPLTLRATKEAL---RRL-RREGLPDGDDL 234


                 ....*.
gi 213417737 286 LGTVWG 291
Cdd:PRK06144 235 IRMCYM 240
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
50-266 5.23e-27

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 110.72  E-value: 5.23e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  50 FPGGSIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL-GTPED 128
Cdd:PRK11730   3 YQGKTLQVDWLEDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGADITEFLSLfAAPEE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 129 G-MAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQ 207
Cdd:PRK11730  83 ElSQWLHFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADN 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 213417737 208 ALKVLSGALKLDSKNALNIGMVEEVLqSSDetKSLEEAQEWLKQFIQGPPE--VIRALKKS 266
Cdd:PRK11730 163 ALEWIAAGKDVRAEDALKVGAVDAVV-APE--KLQEAALALLKQAIAGKLDwkARRQPKLE 220
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 57-300 5.01e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 103.41  E-value: 5.01e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  57 LQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV-KSLGTPEDGMAvcmf 135
Cdd:PRK06688   8 LVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFpKAPPKPPDELA---- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 136 mqnTLTRFMR----LPLISVALVQGWALGGGAEFTTACDFR-------LMTPESKIrfvhkemGIIPSWGGTTRLVEIIG 204
Cdd:PRK06688  84 ---PVNRFLRaiaaLPKPVVAAVNGPAVGVGVSLALACDLVyasesakFSLPFAKL-------GLCPDAGGSALLPRLIG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 205 S-RQALKVLSGAlKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNER 283
Cdd:PRK06688 154 RaRAAEMLLLGE-PLSAEEALRIGLVNRVVPAAE---LDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREA 229

                        250
                 ....*....|....*..
gi 213417737 284 DLLGTVWGGPANLEAIA 300
Cdd:PRK06688 230 AGFGRLLRTPDFREGAT 246
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 61-283 3.63e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 101.35  E-value: 3.63e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKN-TFSSGSDLNAVKSLGTPEDGMAVCMfMQNT 139
Cdd:PRK07657  11 TPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEkAFCAGADLKERAGMNEEQVRHAVSL-IRTT 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 140 LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLD 219
Cdd:PRK07657  90 MEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 213417737 220 SKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNER 283
Cdd:PRK07657 170 AQEAKEIGLVEFVVPAH---LLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEK 230
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
55-287 4.32e-24

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 98.28  E-value: 4.32e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  55 IDLQKEDNgIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLgTPEDGMAVC 133
Cdd:PRK05809   6 VILEKEGH-IAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAgEKAFVAGADISEMKDL-NEEEGRKFG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 134 MFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTpeSKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALKV 211
Cdd:PRK05809  84 LLGNKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIAS--EKAKFGQPEvgLGITPGFGGTQRLARIVGPGKAKEL 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 213417737 212 LSGALKLDSKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLG 287
Cdd:PRK05809 162 IYTGDMINAEEALRIGLVNKVVEPE---KLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFG 234
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 61-267 4.80e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 97.87  E-value: 4.80e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV--KSLGTPEDGMAVcmfMQN 138
Cdd:PRK05870  10 DDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALgaAPGRPAEDGLRR---IYD 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 139 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESK--IRFVhkEMGIIPSWGGTTRLVEIIGSRQALKVLSGAL 216
Cdd:PRK05870  87 GFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALfdARFQ--KLGLHPGGGATWMLQRAVGPQVARAALLFGM 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 213417737 217 KLDSKNALNIGMVEEVlqsSDETksLEEAQEWLKQFIQGPPEVIRALKKSV 267
Cdd:PRK05870 165 RFDAEAAVRHGLALMV---ADDP--VAAALELAAGPAAAPRELVLATKASM 210
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 57-283 1.33e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 97.04  E-value: 1.33e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  57 LQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEdgmavcMFM 136
Cdd:PRK08138  11 LERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATAGAIE------MYL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 137 QNT------LTRfMRLPLIsvALVQGWALGGGAEFTTACDF-------RLMTPESKIrfvhkemGIIPSWGGTTRLVEII 203
Cdd:PRK08138  85 RHTeryweaIAQ-CPKPVI--AAVNGYALGGGCELAMHADIivagesaSFGQPEIKV-------GLMPGAGGTQRLVRAV 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 204 GSRQALK-VLSGALkLDSKNALNIGMVEEVlqsSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNE 282
Cdd:PRK08138 155 GKFKAMRmALTGCM-VPAPEALAIGLVSEV---VEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALE 230


                 .
gi 213417737 283 R 283
Cdd:PRK08138 231 R 231
PLN02600 PLN02600
enoyl-CoA hydratase
 61-300 1.97e-23

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 96.41  E-value: 1.97e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFsGVMMLQLLEKVIE-LENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMfMQN 138
Cdd:PLN02600   2 DSGIVELRLDRPEAKNAI-GKEMLRGLRSAFEkIQADASARVVMLRSSvPGVFCAGADLKERRKMSPSEVQKFVNS-LRS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 139 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 218
Cdd:PLN02600  80 TFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 219 DSKNALNIGMVEEVLQSSDE-TKSLEEAQEwlkqFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTVWGGPANLE 297
Cdd:PLN02600 160 GAREAASMGLVNYCVPAGEAyEKALELAQE----INQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLE 235


                 ...
gi 213417737 298 AIA 300
Cdd:PLN02600 236 GLA 238
PLN02888 PLN02888
enoyl-CoA hydratase
 55-285 3.74e-23

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 95.97  E-value: 3.74e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  55 IDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL--GTPEDGMAv 132
Cdd:PLN02888  11 ILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAAEEVfkGDVKDVET- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 133 cmfmqNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVL 212
Cdd:PLN02888  90 -----DPVAQMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVS 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 213417737 213 SGALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 285
Cdd:PLN02888 165 LTAMPLTAETAERWGLVNHVV---EESELLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEKER 234
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 61-284 8.09e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 95.11  E-value: 8.09e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLN---AVKSLGTPEDGMAvcmfm 136
Cdd:PRK06494  11 KGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAgDKAFSAGNDLKeqaAGGKRGWPESGFG----- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 137 qnTLT-RF-MRLPLIsvALVQGWALGGGAEFTTACD---------FRLmtPESKIrfvhkemGIIPSWGGTTRLVEIIGS 205
Cdd:PRK06494  86 --GLTsRFdLDKPII--AAVNGVAMGGGFELALACDlivaaenatFAL--PEPRV-------GLAALAGGLHRLPRQIGL 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 213417737 206 RQALKVLSGALKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERD 284
Cdd:PRK06494 153 KRAMGMILTGRRVTAREGLELGFVNEVVPAGE---LLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRD 228
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 51-300 2.00e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 93.89  E-value: 2.00e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  51 PGGSIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLnavKSLGTPEDGM 130
Cdd:PRK06190   1 MTEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDL---KELGGDGSAY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 131 AVCMFMQNTLTRF--MRLPLISValVQGWALGGGAEFTTACDFrLMTPEsKIRF--VHKEMGIIPSWGGTTRLVEIIGSR 206
Cdd:PRK06190  78 GAQDALPNPSPAWpaMRKPVIGA--INGAAVTGGLELALACDI-LIASE-RARFadTHARVGILPGWGLSVRLPQKVGIG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 207 QALKV-LSGALkLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 285
Cdd:PRK06190 154 RARRMsLTGDF-LDAADALRAGLVTEVVPHDE---LLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAEA 229

                        250
                 ....*....|....*
gi 213417737 286 LGTvWGGPANLEAIA 300
Cdd:PRK06190 230 ARA-HNRSVSPDGIA 243
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 54-300 1.68e-20

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 88.67  E-value: 1.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  54 SIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLN--AVKSLGTPEDGMA 131
Cdd:PRK09674   2 SELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNemAEKDLAATLNDPR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 132 VCMFMQntLTRFMRlPLIsvALVQGWALGGGAEFTTACDfrLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQAL 209
Cdd:PRK09674  82 PQLWQR--LQAFNK-PLI--AAVNGYALGAGCELALLCD--IVIAGENARFGLPEitLGIMPGAGGTQRLIRSVGKSLAS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 210 K-VLSGAlKLDSKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGT 288
Cdd:PRK09674 155 QmVLTGE-SITAQQAQQAGLVSEVFPPE---LTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTL 230

                        250
                 ....*....|..
gi 213417737 289 VWGGPANLEAIA 300
Cdd:PRK09674 231 LAATEDRHEGIS 242
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 47-267 3.56e-20

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 86.82  E-value: 3.56e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  47 LQQFPGGSIDLQKEDNGIGILTLNNPSrMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTP 126
Cdd:PRK05869   1 MNEFVNVVVSDGSQDAGLATLLLSRPP-TNALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 127 EDGMA--VCmfmQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIG 204
Cdd:PRK05869  80 EADTAarVR---QQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAG 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 213417737 205 SRQALK-VLSGALkLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSV 267
Cdd:PRK05869 157 PSRAKElVFSGRF-FDAEEALALGLIDEMVAPDD---VYDAAAAWARRFLDGPPHALAAAKAGI 216
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
55-304 4.08e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 87.63  E-value: 4.08e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  55 IDLQKEDnGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDL--------NAVKSLGTP 126
Cdd:PRK07509   5 VSVTIED-GIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVksvasspgNAVKLLFKR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 127 EDGMA-----VCMFMQntltrfmRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVE 201
Cdd:PRK07509  84 LPGNAnlaqrVSLGWR-------RLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRG 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 202 IIGSRQALKVLSGALKLDSKNALNIGMVEEVlqsSDETksLEEAQEWLKQFIQGPPEVIRALKKS-----VCSGRELYLE 276
Cdd:PRK07509 157 LVRKDVARELTYTARVFSAEEALELGLVTHV---SDDP--LAAALALAREIAQRSPDAIAAAKRLinrswTASVRALLAR 231

                        250       260
                 ....*....|....*....|....*...
gi 213417737 277 EALQNERdLLgtvwGGPANLEAIAKKGK 304
Cdd:PRK07509 232 ESVEQIR-LL----LGKNQKIAVKAQMK 254
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 54-300 4.32e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 87.28  E-value: 4.32e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  54 SIDLQKEDNG-IGILTLNNPSrMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTF-SSGSDLNavkslgTPEDG-- 129
Cdd:PRK09076   2 MIELDLEIDGhVAILTLNNPP-ANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFfSAGADLN------LFADGdk 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 130 -----MAVCM---FmqNTLTRFMRlplISVALVQGWALGGGAEFTTACDFR-------LMTPESKIrfvhkemGIIPSWG 194
Cdd:PRK09076  75 avareMARRFgeaF--EALSAFRG---VSIAAINGYAMGGGLECALACDIRiaeeqaqMALPEASV-------GLLPCAG 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 195 GTTRLVEIIGSRQALKVLSGALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELY 274
Cdd:PRK09076 143 GTQNLPWLVGEGWAKRMILCGERVDAATALRIGLVEEVV---EKGEAREAALALAQKVANQSPSAVAACKTLIQAARNGP 219

                        250       260
                 ....*....|....*....|....*.
gi 213417737 275 LEEALQNERDLLGTVWGGPANLEAIA 300
Cdd:PRK09076 220 RAAALALERELFVDLFDTEDQREGVN 245
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 54-284 4.52e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 87.40  E-value: 4.52e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  54 SIDLQKEDNgIGILTLNNPSRMNAFSGVMMLQLLEKVIELENwTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVC 133
Cdd:PRK07659   7 SVVVKYEGR-VATIMLNRPEALNALDEPMLKELLQALKEVAE-SSAHIVVLRGNGRGFSAGGDIKMMLSSNDESKFDGVM 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 134 MFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS 213
Cdd:PRK07659  85 NTISEIVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIW 164

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 213417737 214 GALKLDSKNALNIGMVEEVLQSSdetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERD 284
Cdd:PRK07659 165 EGKKLSATEALDLGLIDEVIGGD----FQTAAKQKISEWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKR 231
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
57-236 1.45e-19

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 88.80  E-value: 1.45e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  57 LQKEDNGIGILTLNNP-SRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAK-NTFSSGSDLNAVKSLGTPEDGMAVCM 134
Cdd:PRK11154   9 LNVREDNIAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKELKGVVFISGKpDNFIAGADINMLAACKTAQEAEALAR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 135 FMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALK-V 211
Cdd:PRK11154  89 QGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKTVLGLPEvqLGLLPGSGGTQRLPRLIGVSTALDmI 168

                        170       180
                 ....*....|....*....|....*
gi 213417737 212 LSGAlKLDSKNALNIGMVEEVLQSS 236
Cdd:PRK11154 169 LTGK-QLRAKQALKLGLVDDVVPHS 192
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 47-285 4.81e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 84.76  E-value: 4.81e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  47 LQQFPGGSIDLQKEDnGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAV-KSLG 124
Cdd:PRK06127   5 SISSPTGKLLAEKTG-GLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAgEKAFVSGADISQFeESRS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 125 TPEdgmAVCMFMQNTLTRFMRL---PLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVE 201
Cdd:PRK06127  84 DAE---AVAAYEQAVEAAQAALadyAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVD 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 202 IIGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKSVcsgRELYLEEAlq 280
Cdd:PRK06127 161 LVGPSAAKDLFYTARRFDAAEALRIGLVHRVTAADD----LEtALADYAATIAGNAPLTLRAAKRAI---AELLKDEP-- 231


                 ....*
gi 213417737 281 nERDL 285
Cdd:PRK06127 232 -ERDM 235
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 55-232 2.36e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 83.13  E-value: 2.36e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  55 IDLQKEDnGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNA-VKSLGTPEDGMAVC 133
Cdd:PRK08260   6 IRYDVAD-GIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLSAgGNTFDLDAPRTPVE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 134 MFM----------------QNTLTRF-MRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGT 196
Cdd:PRK08260  85 ADEedradpsddgvrdgggRVTLRIFdSLKPVI--AAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASS 162

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 213417737 197 TRLVEIIGSRQALK-VLSGALkLDSKNALNIGMVEEV 232
Cdd:PRK08260 163 WFLPRLVGLQTALEwVYSGRV-FDAQEALDGGLVRSV 198
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 61-285 4.48e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 81.88  E-value: 4.48e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENwTEGKGLIVRGAKNTFSSGSDLN--AVKSLGTPED-GMAVCMFMQ 137
Cdd:PRK08140  11 EAGVATLTLNRPDKLNSFTREMHRELREALDQVED-DGARALLLTGAGRGFCAGQDLAdrDVTPGGAMPDlGESIETFYN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 138 NTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKirFVHK--EMGIIPSWGGTTRLVEIIGSRQALKVLSGA 215
Cdd:PRK08140  90 PLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSAS--FIQAfvKIGLVPDSGGTWFLPRLVGMARALGLALLG 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 216 LKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 285
Cdd:PRK08140 168 EKLSAEQAEQWGLIWRVV---DDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDL 234
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 64-285 2.35e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 79.70  E-value: 2.35e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  64 IGILTLNNPSRMNAFSGVMMLQLLEKVIELENwTEGKGLIV-RGAKNTFSSGSDLNAVKSLgtpeDGMAVcmFMQNTLT- 141
Cdd:PRK05862  14 VGLITLNRPKALNALNDALMDELGAALAAFDA-DEGIGAIViTGSEKAFAAGADIKEMADL----SFMDV--YKGDYITn 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 142 ----RFMRLPLIsvALVQGWALGGGAEFTTACDF-------RLMTPESKirfvhkeMGIIPSWGGTTRLVEIIGSRQALK 210
Cdd:PRK05862  87 wekvARIRKPVI--AAVAGYALGGGCELAMMCDIiiaadtaKFGQPEIK-------LGVLPGMGGSQRLTRAVGKAKAMD 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 213417737 211 VLSGALKLDSKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDL 285
Cdd:PRK05862 158 LCLTGRMMDAAEAERAGLVSRVVPAD---KLLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRL 229
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
61-283 2.78e-16

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 77.08  E-value: 2.78e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLE--KVIElENWTEGKGLIVRGAKNTFSSGSDL----NAVKSLGT-PEDGMAVC 133
Cdd:PRK05981  11 DGGVAILTLDHPEVMNAVSIDMLGGLAEalDAIE-DGKAEVRCLVLTGAGRGFCTGANLqgrgSGGRESDSgGDAGAALE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 134 MFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS 213
Cdd:PRK05981  90 TAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSL 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 214 GALKLDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNER 283
Cdd:PRK05981 170 LGEKLPAETALQWGLVNRVV---DDAELMAEAMKLAHELANGPTVALGLIRKLYWDSPENDFEEQLNLER 236
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
66-303 3.17e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 73.98  E-value: 3.17e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  66 ILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGtPEDGMAVCMFMQNTLT---- 141
Cdd:PRK07799  17 IVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKKP-PGDSFKDGSYDPSRIDallk 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 142 -RFMRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDS 220
Cdd:PRK07799  96 gRRLTKPLI--AAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 221 KNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLlgtvwGGPANLEAIA 300
Cdd:PRK07799 174 AEAKEIGLIGHVV---PDGQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKI-----GIPVFLSEDA 245


                 ...
gi 213417737 301 KKG 303
Cdd:PRK07799 246 KEG 248
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
63-289 4.24e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 73.49  E-value: 4.24e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  63 GIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV---KSLGTPEDGMAvcmfmqnT 139
Cdd:PRK08252  12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAFargERPSIPGRGFG-------G 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 140 LT-RFMRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALK-VLSGALk 217
Cdd:PRK08252  85 LTeRPPRKPLI--AAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMElALTGDM- 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 213417737 218 LDSKNALNIGMVEEVlqsSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERDLLGTV 289
Cdd:PRK08252 162 LTAERAHELGLVNRL---TEPGQALDAALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPV 230
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
61-264 7.24e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 73.08  E-value: 7.24e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTP----------EDGM 130
Cdd:PRK06142  13 ADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGQlgkdglarprTDLR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 131 AVCMFMQNTLTRF--MRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKirFVHKE--MGIIPSWGGTTRLVEIIGSR 206
Cdd:PRK06142  93 REILRLQAAINAVadCRKPVI--AAVQGWCIGGGVDLISACDMRYASADAK--FSVREvdLGMVADVGSLQRLPRIIGDG 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 213417737 207 QALKVLSGALKLDSKNALNIGMVEEVLqsSDETKSLEEAQEWLKQFIQGPPEVIRALK 264
Cdd:PRK06142 169 HLRELALTGRDIDAAEAEKIGLVNRVY--DDADALLAAAHATAREIAAKSPLAVRGTK 224
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 60-298 1.51e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 71.59  E-value: 1.51e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  60 EDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENwTEGKGLIVRGAKNTFSSGSDLNAVkslGTPEDGMAVCMFMQNT 139
Cdd:PRK07854   6 RDGQVLTIELQRPERRNALNAELCEELREAVRKAVD-ESARAIVLTGQGTVFCAGADLSGD---VYADDFPDALIEMLHA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 140 LTRfmrLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGI-IPSWgGTTRLVEIIGSRQALKVLSGALKL 218
Cdd:PRK07854  82 IDA---APVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIaLDNW-TIRRLSSLVGGGRARAMLLGAEKL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 219 DSKNALNIGMVEEVlqssdetKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRElyLEEALQNERDLLGTVWGGPANLEA 298
Cdd:PRK07854 158 TAEQALATGMANRI-------GTLADAQAWAAEIAGLAPLALQHAKRVLNDDGA--IEEAWPAHKELFDKAWASQDAIEA 228
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
61-279 4.08e-14

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 70.88  E-value: 4.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPsRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNT 139
Cdd:PRK03580  10 NGSILEITLDRP-KANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAgEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLT 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 140 LTRFMRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLD 219
Cdd:PRK03580  89 EIFDLDKPVI--AAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMD 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 220 SKNALNIGMVEEVLQSsdeTKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEAL 279
Cdd:PRK03580 167 AEEALRWGIVNRVVPQ---AELMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAY 223
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
61-280 4.71e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 70.77  E-value: 4.71e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEG-KGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVcMFMQNT 139
Cdd:PRK09245  10 DGHIVTLTMNRPETRNALSDNDAVDALVAACAAINADRSvRAVILTGAGTAFSSGGNVKDMRARVGAFGGSPA-DIRQGY 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 140 LTRFMRLPLI-------SVALVQGWALGGGAEFTTACDFRLMTPESKI--RFVhkEMGIIPSWGGTTRLVEIIG-SRQAL 209
Cdd:PRK09245  89 RHGIQRIPLAlynlevpVIAAVNGPAIGAGCDLACMCDIRIASETARFaeSFV--KLGLIPGDGGAWLLPRIIGmARAAE 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 213417737 210 KVLSGAlKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQ 280
Cdd:PRK09245 167 MAFTGD-AIDAATALEWGLVSRVVPADQ---LLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLE 233
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 54-264 6.30e-14

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 70.22  E-value: 6.30e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  54 SIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL------GTPE 127
Cdd:PRK05674   6 TIELIRDPRGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLAWMQQSadldynTNLD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 128 DGMAVCMFMQNtltrFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTrLVEIIGSRQ 207
Cdd:PRK05674  86 DARELAELMYN----LYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPF-VVKAIGERA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 213417737 208 ALKVLSGALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALK 264
Cdd:PRK05674 161 ARRYALTAERFDGRRARELGLLAESYPAAE----LEaQVEAWIANLLLNSPQALRASK 214
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 61-278 7.00e-14

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 70.42  E-value: 7.00e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVM---MLQLLEkviELENWTEGKGLIVRGAKNTFSSGSDLNAV--KSLGTPEdgMAVCMF 135
Cdd:PRK09120  15 EDGIAWVTLNRPEKRNAMSPTLnreMIDVLD---ALEFDDDAGVLVLTGAGDAWSAGMDLKEYfrETDAQPE--ILQERI 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 136 MQNTLTRFMRL---PLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQAL-KV 211
Cdd:PRK09120  90 RREAYGWWRRLrwyQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALyYI 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 213417737 212 LSGALkLDSKNALNIGMVEEVLQSSD-ETKSLEEAQEWLKQfiqgPPEVIRALKKSVCSGRELYLEEA 278
Cdd:PRK09120 170 MTGET-FTGRKAAEMGLVNESVPLAQlRARTRELAAKLLEK----NPVVLRAAKDGFKRVRELTWDQA 232
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
61-266 1.71e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 68.83  E-value: 1.71e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAV------KSLGTPEDGMAVCM 134
Cdd:PRK06563   6 RGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVapklaaGGFPFPEGGIDPWG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 135 FMQNTLTRfmrlPLISValVQGWALGGGAEFTTACDFRLMTpeSKIRFVHKEM--GIIPSWGGTTRLVEIIGSRQALKVL 212
Cdd:PRK06563  86 TVGRRLSK----PLVVA--VQGYCLTLGIELMLAADIVVAA--DNTRFAQLEVqrGILPFGGATLRFPQAAGWGNAMRYL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 213417737 213 SGALKLDSKNALNIGMVEEVLQSSDE-TKSLEEAQEWLKQfiqgPPEVIRALKKS 266
Cdd:PRK06563 158 LTGDEFDAQEALRLGLVQEVVPPGEQlERAIELAERIARA----APLGVQATLAS 208
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 61-279 2.64e-13

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 68.78  E-value: 2.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL----GTPEDGMAV---- 132
Cdd:PLN02664  15 NSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSIseqsSSGDRGRSGerlr 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 133 --CMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALK 210
Cdd:PLN02664  95 rkIKFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAME 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 211 VLSGALKLDSKNALNIGMVEEVLQSSDEtksLEEAQEWLKQFIQG-PPEVIRALKKSVCSGRELYLEEAL 279
Cdd:PLN02664 175 LALTGRRFSGSEAKELGLVSRVFGSKED---LDEGVRLIAEGIAAkSPLAVTGTKAVLLRSRELSVEQGL 241
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 51-277 1.37e-12

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 66.83  E-value: 1.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  51 PGGSIDLQKEDNGIGILTLNNPSrMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA--KNTFSSGSDLNAVKSLGTPED 128
Cdd:PLN03214   9 ATPGVRVDRRPGGIAVVWLAKEP-VNSMTLAMWRSLDDALTALENDPTVRGVVFASGlrRDVFTAGNDIAELYAPKTSAA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 129 GMAVCMFMQNT-LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGI-IPSWGGTTRLVEIIGSR 206
Cdd:PLN03214  88 RYAEFWLTQTTfLVRLLRSRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRK 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 213417737 207 QA-LKVLSGALkLDSKNALNIGMVEEVLQSSdetKSLEEAQEWLKQFIQGPPEVIRALKKSV----CSGRELYLEE 277
Cdd:PLN03214 168 VAeSLLLRGRL-VRPAEAKQLGLIDEVVPAA---ALMEAAASAMERALKLPSAARAATKALLreefSAAWEAYYEE 239
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
61-256 1.66e-12

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 66.53  E-value: 1.66e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLN----AVKSLGTPEdgmaVCMF- 135
Cdd:PRK08258  24 DDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHeiigPLTKMDMPE----LLAFt 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 136 -MQNTLTRFMR-LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPS-WGGTTRLVEIIGSRQALKVL 212
Cdd:PRK08258 100 rMTGDLVKAMRaCPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAGAdMGACALLPRIIGQGRASELL 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 213417737 213 SGALKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGP 256
Cdd:PRK08258 180 YTGRSMSAEEGERWGFFNRLVEPEE---LLAEAQALARRLAAGP 220
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 62-234 3.12e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 67.17  E-value: 3.12e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737   62 NGIGILTLNNP-SRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAK-NTFSSGSDLNAVKSLGTPEDGMAVCMFMQNT 139
Cdd:TIGR02441  21 GDVAVVKIDSPnSKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKpGSFVAGADIQMIAACKTAQEVTQLSQEGQEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  140 LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGALK 217
Cdd:TIGR02441 101 FERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMMLTGKK 180

                         170
                  ....*....|....*..
gi 213417737  218 LDSKNALNIGMVEEVLQ 234
Cdd:TIGR02441 181 IRADRAKKMGIVDQLVD 197
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 61-237 3.31e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 65.50  E-value: 3.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGtPEDGMA---VCMFMQ 137
Cdd:PRK06210  13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQTID-PSDGRRdtdVRPFVG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 138 N----TLTRF-----MRLPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQA 208
Cdd:PRK06210  92 NrrpdYQTRYhfltaLRKPVI--AAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANA 169

                        170       180
                 ....*....|....*....|....*....
gi 213417737 209 LKVLSGALKLDSKNALNIGMVEEVLQSSD 237
Cdd:PRK06210 170 LDLLLSARTFYAEEALRLGLVNRVVPPDE 198
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 63-229 5.78e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 64.85  E-value: 5.78e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  63 GIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNA------VKSLGTPEDGMAVCMFM 136
Cdd:PRK05864  19 EIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKSagvvphVEGLTRPTYALRSMELL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 137 QNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLV-EIIGSRQALKVLSGA 215
Cdd:PRK05864  99 DDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASELGLSYLLpRAIGSSRAFEIMLTG 178

                        170
                 ....*....|....
gi 213417737 216 LKLDSKNALNIGMV 229
Cdd:PRK05864 179 RDVDAEEAERIGLV 192
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 67-267 7.33e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 64.18  E-value: 7.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  67 LTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLG--TPEDGMAVCMFMQNTLTRFM 144
Cdd:PRK05995  17 VTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNWMKKMAgySDDENRADARRLADMLRAIY 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 145 RLPLISVALVQGWALGGGAEFTTACDF-------RLMTPESKIrfvhkemGIIPSwggtT---RLVEIIGSRQALKVLSG 214
Cdd:PRK05995  97 RCPKPVIARVHGDAYAGGMGLVAACDIavaadhaVFCLSEVRL-------GLIPA----TispYVIRAMGERAARRYFLT 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 213417737 215 ALKLDSKNALNIGMVEEVLqSSDEtksLEEAQEWL-KQFIQGPPEVIRALKKSV 267
Cdd:PRK05995 166 AERFDAAEALRLGLVHEVV-PAEA---LDAKVDELlAALVANSPQAVRAGKRLV 215
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
 55-266 8.38e-12

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 64.10  E-value: 8.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737   55 IDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLeKVIELENWTEGKGLIV---RGAKnTFSSGSDlNAVKSLGTPEDGMA 131
Cdd:TIGR01929   4 IRYEKSTDGIAKITINRPQVRNAFRPLTVKEII-QALDDAREDPDIGVVIltgAGDK-AFCSGGD-QKVRGDYGYIDDSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  132 VCMFMQNTLTRFMR-LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALK 210
Cdd:TIGR01929  81 VHRLNVLDVQRQIRtCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQKKARE 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 213417737  211 VLSGALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKS 266
Cdd:TIGR01929 161 IWFLCRQYDAKQALDMGLVNTVVPLAD----LEkETVRWCREILQKSPMAIRMLKAA 213
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
60-247 1.61e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 63.11  E-value: 1.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  60 EDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENwtEGKGLIVRGAKNTFSSGSDLNAVKSLgTPEDGMAVCMFMQNT 139
Cdd:PRK08150   8 LDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPE--GVRAVVLHGEGDHFCAGLDLSELRER-DAGEGMHHSRRWHRV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 140 LTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIG-SRQALKVLSGALkL 218
Cdd:PRK08150  85 FDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGvARMTDMMLTGRV-Y 163

                        170       180
                 ....*....|....*....|....*....
gi 213417737 219 DSKNALNIGMVEEVLQSSdetKSLEEAQE 247
Cdd:PRK08150 164 DAQEGERLGLAQYLVPAG---EALDKAME 189
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
51-282 1.80e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 62.99  E-value: 1.80e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  51 PGGSIDLQKeDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVkslGTPE--- 127
Cdd:PRK08259   1 MSMSVRVER-NGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAV---GTGRgnr 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 128 -----DG-MAVcmfmqntlTRfMRL--PLIsvALVQGWALGGGAEFTTACDFRLMTPESKI-----RFvhkemGIIPSWG 194
Cdd:PRK08259  77 lhpsgDGpMGP--------SR-MRLskPVI--AAVSGYAVAGGLELALWCDLRVAEEDAVFgvfcrRW-----GVPLIDG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 195 GTTRLVEIIGSRQALK-VLSGAlKLDSKNALNIGMVEEVLQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVCSGREL 273
Cdd:PRK08259 141 GTVRLPRLIGHSRAMDlILTGR-PVDADEALAIGLANRVVPKGQ---ARAAAEELAAELAAFPQTCLRADRLSALEQWGL 216


                 ....*....
gi 213417737 274 YLEEALQNE 282
Cdd:PRK08259 217 PEEAALANE 225
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 61-236 5.38e-11

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 61.97  E-value: 5.38e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENwTEGKGLIVRGAKNT--FSSGSDLNAVKSLGtpEDGMAVCMFMQN 138
Cdd:PRK11423  11 INKIATITFNNPAKRNALSKVLIDDLMQALSDLNR-PEIRVVILRAPSGSkvWSAGHDIHELPSGG--RDPLSYDDPLRQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 139 TLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 218
Cdd:PRK11423  88 ILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPI 167

                        170
                 ....*....|....*...
gi 213417737 219 DSKNALNIGMVEEVLQSS 236
Cdd:PRK11423 168 TAQRALAVGILNHVVEVE 185
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 59-281 1.24e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 57.74  E-value: 1.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  59 KEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLgTPEDGMAVcmfmq 137
Cdd:PRK06143  12 RDDRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAgEKAFIGGADIKEMATL-DQASAEAF----- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 138 ntLTRFMRL-------PLISVALVQGWALGGGAEFTTACDFRLMT-------PESKIrfvhkemGiIPSWGGTTRLVEII 203
Cdd:PRK06143  86 --ISRLRDLcdavrhfPVPVIARIPGWCLGGGLELAAACDLRIAAhdaqfgmPEVRV-------G-IPSVIHAALLPRLI 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 213417737 204 G-SRQALKVLSGALkLDSKNALNIGMVEEVLQSSDETKSLEEAQEWLKQFiqgPPEVIRALKKSVCSGRELYLEEALQN 281
Cdd:PRK06143 156 GwARTRWLLLTGET-IDAAQALAWGLVDRVVPLAELDAAVERLAASLAGC---GPQALRQQKRLLREWEDMPLDVAIDD 230
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 54-282 1.99e-09

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 56.90  E-value: 1.99e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  54 SIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGsdlnavkslGTPEDGMAVC 133
Cdd:PRK07110   5 VVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATG---------GTQEGLLSLQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 134 M-FMQNTLTRFMRLPL---ISV-ALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQA 208
Cdd:PRK07110  76 TgKGTFTEANLYSLALncpIPViAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALG 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 213417737 209 LKVLSGALKLDSKNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNE 282
Cdd:PRK07110 156 QEMLLTARYYRGAELKKRGVPFPVL-PRAEV--LEKALELARSLAEKPRHSLVLLKDHLVADRRRRLPEVIEQE 226
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 57-239 5.98e-09

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 56.65  E-value: 5.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  57 LQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNA-VKSLGTPEDGMAVCMF 135
Cdd:PLN02988  12 LVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAvVRDIEQGNWRLGANFF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 136 MQNTLTRFMRLPL--ISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS 213
Cdd:PLN02988  92 SDEYMLNYVMATYskAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLT 171

                        170       180
                 ....*....|....*....|....*.
gi 213417737 214 GAlKLDSKNALNIGMVEEVLQSSDET 239
Cdd:PLN02988 172 GA-RLDGAEMLACGLATHFVPSTRLT 196
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
54-300 9.24e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 55.07  E-value: 9.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  54 SIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSL--GTPED--- 128
Cdd:PRK07468   5 TIRIAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWMRAQmtADRATrie 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 129 ---GMAVCMFMQNTLTRfmrlPLIsvALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTrLVEIIGS 205
Cdd:PRK07468  85 earRLAMMLKALNDLPK----PLI--GRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPY-VVARMGE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 206 RQALKVLSGALKLDSKNALNIGMVEEVLQSSDETKSLEEAqewLKQFIQGPPEVIRALKKSVcsgRELYL---EEALQNE 282
Cdd:PRK07468 158 ANARRVFMSARLFDAEEAVRLGLLSRVVPAERLDAAVEAE---VTPYLSCAPGAVAAAKALV---RALGApidEAVIDAT 231

                        250
                 ....*....|....*...
gi 213417737 283 RDLLGTVWGGPANLEAIA 300
Cdd:PRK07468 232 IEALADTWETEEAREGIA 249
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 61-285 1.81e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 54.36  E-value: 1.81e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQ--N 138
Cdd:PRK07260   9 EDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSLVKIAElvN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 139 TLTRFM-RLPLISVALVQGWALGGGAEFTTACDFRLMTpeSKIRFVHK--EMGIIPSWGGTTRLVEIIGSRQALKVLSGA 215
Cdd:PRK07260  89 EISFAIkQLPKPVIMCVDGAVAGAAANMAVAADFCIAS--TKTKFIQAfvGVGLAPDAGGLFLLTRAIGLNRATHLAMTG 166

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 213417737 216 LKLDSKNALNIGMVEEVLQSSDETKSLEEAqewLKQFIQGPPEVIRALK----KSVCSGRELYLEEALQNERDL 285
Cdd:PRK07260 167 EALTAEKALEYGFVYRVAESEKLEKTCEQL---LKKLRRGSSNSYAAIKslvwESFFKGWEDYAKLELALQESL 237
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 63-282 3.03e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 53.63  E-value: 3.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  63 GIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTpEDgmavcmfMQNT--- 139
Cdd:PRK06072   9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEFAPDFA-ID-------LRETfyp 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 140 LTRFMRLP-LISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGAlKL 218
Cdd:PRK06072  81 IIREIRFSdKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVLGG-EF 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 213417737 219 DSKNALNIGMVEevlQSSDetkSLEEAQEWLKQFIQGPPEVIRALKKSVcsGRELY--LEEALQNE 282
Cdd:PRK06072 160 TAEEAERWGLLK---ISED---PLSDAEEMANRISNGPFQSYIAAKRMI--NLVLYndLEEFLEYE 217
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
140-264 2.45e-07

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 51.18  E-value: 2.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 140 LTRFMrlPLISVALVQGWALGGGAEFTTACDFRLMTPE-SKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKL 218
Cdd:PRK08321 130 LIRFM--PKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTY 207

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 213417737 219 DSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALK 264
Cdd:PRK08321 208 SAEEAHDMGAVNAVVPHAE----LEtEALEWAREINGKSPTAMRMLK 250
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 69-209 3.21e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 51.13  E-value: 3.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  69 LNNPSRMNAFSgVMMLQLLEKVieLENWTEGKGL---IVRGAKNTFSSGSDLNAVKSLgTPEDGMAVCMFMQNTLTRFMR 145
Cdd:PLN02851  57 LNRPSSLNALT-IPMVARLKRL--YESWEENPDIgfvLMKGSGRAFCSGADVVSLYHL-INEGNVEECKLFFENLYKFVY 132

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 213417737 146 L------PliSVALVQGWALGGGAEFTTACDFRLMTpeSKIRFVHKE--MGIIPSWGGT---TRLVEIIGSRQAL 209
Cdd:PLN02851 133 LqgtylkP--NVAIMDGITMGCGAGISIPGMFRVVT--DKTVFAHPEvqMGFHPDAGASyylSRLPGYLGEYLAL 203
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
61-239 3.34e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 50.45  E-value: 3.34e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVcmFMQNTL 140
Cdd:PRK07827  13 DGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAGGGGGDPYDAAV--ARAREM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 141 TRFMR----LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGAl 216
Cdd:PRK07827  91 TALLRaiveLPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYLTGE- 169

                        170       180
                 ....*....|....*....|...
gi 213417737 217 KLDSKNALNIGMVEEVLQSSDET 239
Cdd:PRK07827 170 KFGAAEAARIGLVTAAADDVDAA 192
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
63-278 6.11e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 49.79  E-value: 6.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  63 GIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLN--AVKSLGTPEDGMAVCMFMQnTL 140
Cdd:PRK06023  15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQdfLAAAMGGTSFGSEILDFLI-AL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 141 TRFMRlPLISValVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGALKLDS 220
Cdd:PRK06023  94 AEAEK-PIVSG--VDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSA 170

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 213417737 221 KNALNIGMVEEVLQSSD-ETKSLEEAQEWLKQfiqgPPEVIRALKKSVCSGRELYL----EEA 278
Cdd:PRK06023 171 EAAQEAGLIWKIVDEEAvEAETLKAAEELAAK----PPQALQIARDLMRGPREDILaridEEA 229
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 46-262 7.09e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 50.18  E-value: 7.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  46 TLQQFPGGSIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKvieLENWTE---GKGLIVRGAKNTFSSGSDLNAVKS 122
Cdd:PLN02874   3 QQVQNPAEEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEF---LEQWEKddsVELIIIKGAGRAFSAGGDLKMFYD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 123 LGTPEDG-MAVCMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMT-------PESKIRFvHKEMG---IIP 191
Cdd:PLN02874  80 GRESDDScLEVVYRMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTektvfatPEASVGF-HTDCGfsyILS 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 213417737 192 swggttRLVEIIGSRQAlkvLSGAlKLDSKNALNIGMVEEVLQSsdetKSLEEAQEWLKQFIQGPPEVIRA 262
Cdd:PLN02874 159 ------RLPGHLGEYLA---LTGA-RLNGKEMVACGLATHFVPS----EKLPELEKRLLNLNSGDESAVQE 215
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 57-170 1.06e-06

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 49.17  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  57 LQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDL---NAVKSLGTPEDGMAVC 133
Cdd:PRK08139  14 LREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLkemRAARGLAYFRALFARC 93

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 213417737 134 MFMQNTLTRfMRLPLIsvALVQGWALGGGAEFTTACD 170
Cdd:PRK08139  94 SRVMQAIVA-LPQPVI--ARVHGIATAAGCQLVASCD 127
PLN02921 PLN02921
naphthoate synthase
 63-266 4.32e-06

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 47.47  E-value: 4.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  63 GIGILTLNNPSRMNAFSGVMMLQLLEKvieLENWTEGK--GLIVRGAKNT--FSSGSDlNAVKSLG--TPEDGMAvcmfM 136
Cdd:PLN02921  76 GIAKITINRPERRNAFRPRTVKELQRA---FNDARDDSsvGVIILTGKGTkaFCSGGD-QAVRGKDgyVGPDDAG----R 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 137 QNTLTRFM---RLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS 213
Cdd:PLN02921 148 LNVLDLQIqirRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWF 227

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 213417737 214 GALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALKKS 266
Cdd:PLN02921 228 LARFYTASEALKMGLVNTVVPLDE----LEgETVKWCREILRNSPTAIRVLKSA 277
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
61-294 4.91e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 47.34  E-value: 4.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  61 DNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDL------NAVKSLGTPEDGM--AV 132
Cdd:PRK08272  17 TGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLsayaegSSSGGGGGAYPGKrqAV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 133 C---------MFMQNTLTRFMRLPLI-------SVALVQGWALGGGAEFTTACDFRLMTPESKIrfvhkemGIIPS--WG 194
Cdd:PRK08272  97 NhlpddpwdpMIDYQMMSRFVRGFMSlwhahkpTVAKVHGYCVAGGTDIALHCDQVIAADDAKI-------GYPPTrvWG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 195 GTT------RLveiiGSRQALKVLSGALKLDSKNALNIGMVEEVLQSSDetksLEEAQEWLKQFIQG-PPEVIRALKKSV 267
Cdd:PRK08272 170 VPAtgmwayRL----GPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEE----LDERTERLVERIAAvPVNQLAMVKLAV 241

                        250       260
                 ....*....|....*....|....*..
gi 213417737 268 CSGRELYLEEALQnerdLLGTVWGGPA 294
Cdd:PRK08272 242 NSALLQQGVATSQ----MLATVFDGIA 264
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 64-285 7.26e-06

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 46.69  E-value: 7.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737   64 IGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNAVKSLGTPEDGMAVCMF------M 136
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAgERAFCAGGDVRALYEAAKAGGGEAGRDFfreeyrL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  137 QNTLTRFMRlPLisVALVQGWALGGGAEFTTACDFRLMT-------PESKIrfvhkemGIIPSWGGT---TRL-VEI--- 202
Cdd:pfam16113  81 NYLIATYPK-PY--VALMDGIVMGGGVGLSVHGSFRVVTertrfamPETAI-------GLFPDVGGSyflSRLpGELgly 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  203 -------IGSRQALK-------VLSGAL-----KLDSKNALNIGMVEEVL-----QSSDETKSLEEAQEWLKQFIQGP-- 256
Cdd:pfam16113 151 laltgarLNGADALAaglathyVPSARLpaleeALAALDWSDPADVDAVLaefaeESDPPPSPLAAHREAIDRCFSADtv 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 213417737  257 PEVIRALKK---------------------SVC-------SGRELYLEEALQNERDL 285
Cdd:pfam16113 231 EEIIAALEAeadgdewaaetlktlrkrsptSLKvtlrqlrRGRKLSLAECLRMEYRL 287
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
51-285 1.20e-05

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 45.84  E-value: 1.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  51 PGGSIDLQKEDNgIGILTLNNPSrMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLnavKSLGTPEDGm 130
Cdd:PRK06495   2 MMSQLKLEVSDH-VAVVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADL---KGRPDVIKG- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 131 AVCMFMQNTLTRFMRLPLIS-----VALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIpswGGTTRLVEIIG- 204
Cdd:PRK06495  76 PGDLRAHNRRTRECFHAIREcakpvIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGh 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 205 SRQALKVLSGaLKLDSKNALNIGMVEEVLqSSDETksLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQNERD 284
Cdd:PRK06495 153 SLTRRMMLTG-YRVPAAELYRRGVIEACL-PPEEL--MPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQD 228


                 .
gi 213417737 285 L 285
Cdd:PRK06495 229 I 229
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
59-192 1.50e-05

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 45.44  E-value: 1.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  59 KEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENwtEGKGLIVRGAKNTFSSGSDLNAVKSLgtPEDGMAVcMFMQN 138
Cdd:PRK07112   9 RQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEH--AATIVVLEGLPEVFCFGADFSAIAEK--PDAGRAD-LIDAE 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 139 TL----TRFMRLPLISVALVQGWALGGGAEFTTACDfrLMTPESKIRFVHKEM--GIIPS 192
Cdd:PRK07112  84 PLydlwHRLATGPYVTIAHVRGKVNAGGIGFVAASD--IVIADETAPFSLSELlfGLIPA 141
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 57-264 4.04e-05

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 44.11  E-value: 4.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  57 LQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGA-KNTFSSGSDLNaVKSLGTPEDGMAVCMF 135
Cdd:PRK07396  16 LYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAgDKAFCSGGDQK-VRGYGGYVDDDGVPRL 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 136 MQNTLTRFMR-LPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSG 214
Cdd:PRK07396  95 NVLDLQRLIRtCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFL 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 213417737 215 ALKLDSKNALNIGMVEEVLQSSDetksLE-EAQEWLKQFIQGPPEVIRALK 264
Cdd:PRK07396 175 CRQYDAQEALDMGLVNTVVPLAD----LEkETVRWCREMLQNSPMALRCLK 221
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 139-216 4.74e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 44.13  E-value: 4.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 139 TLTRFMRLPLISVALVQGWALGGGAEFTTACDF-------RLMTPEskIRFvhkemGIIPSWGGTTRLVEIIGSRQALK- 210
Cdd:PRK08788 113 AFHRGFGAGAISIALVQGDALGGGFEAALSHHTiiaergaKMGFPE--ILF-----NLFPGMGAYSFLARRVGPKLAEEl 185


                 ....*.
gi 213417737 211 VLSGAL 216
Cdd:PRK08788 186 ILSGKL 191
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 69-262 5.56e-05

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 44.29  E-value: 5.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  69 LNNPSRMNAFSGVMMLQLlEKVieLENWTEGKGL---IVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMqNTLTRFMR 145
Cdd:PLN02157  52 LNRPPALNALTTHMGYRL-QKL--YKNWEEDPNIgfvMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIREFF-SSLYSFIY 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 146 L------PliSVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLSGaLKLD 219
Cdd:PLN02157 128 LlgtylkP--HVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTG-LKLS 204

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 213417737 220 SKNALNIGMVEEVLQsSDETKSLEEAqewLKQFIQGPPEVIRA 262
Cdd:PLN02157 205 GAEMLACGLATHYIR-SEEIPVMEEQ---LKKLLTDDPSVVES 243
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
54-266 5.76e-04

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 40.77  E-value: 5.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  54 SIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVC 133
Cdd:PRK07327  12 ALRFDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDLALVEEMADDFEVRARV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 134 MFMQNTLTRFM---RLPLISValVQGWALGGGAEFTTACDFRLMTPESKIRfvhkemgiipswGGTTRLVEIIGSRQAL- 209
Cdd:PRK07327  92 WREARDLVYNVincDKPIVSA--IHGPAVGAGLVAALLADISIAAKDARII------------DGHTRLGVAAGDHAAIv 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 213417737 210 -KVLSGALK----------LDSKNALNIGMVEEVLqssDETKSLEEAQEWLKQFIQGPPEVIRALKKS 266
Cdd:PRK07327 158 wPLLCGMAKakyylllcepVSGEEAERIGLVSLAV---DDDELLPKALEVAERLAAGSQTAIRWTKYA 222
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
57-194 8.48e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 40.32  E-value: 8.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  57 LQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDL--------NAVKSLGTPED 128
Cdd:PRK12478   8 LYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFgggfqhwgEAMMTDGRWDP 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 213417737 129 GMAVCMFMQNTLT---RFM---RLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMgiipsWG 194
Cdd:PRK12478  88 GKDFAMVTARETGptqKFMaiwRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRM-----WG 154
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
 57-239 1.57e-03

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 39.31  E-value: 1.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737  57 LQKEDNgIGILTLN-------NPSRMNAfsgvmMLQLLEKVieLENWTEGKGLIVRGAKNTFSSGSDLNAVKSLGTPEDG 129
Cdd:PLN02267   4 LEKRGN-LFILTLTgdgehrlNPTLIDS-----IRSALRQV--KSQATPGSVLITTAEGKFFSNGFDLAWAQAAGSAPSR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 213417737 130 MAV-CMFMQNTLTRFMRLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVhKEMGI---IPSWgGTTRLVEIIGS 205
Cdd:PLN02267  76 LHLmVAKLRPLVADLISLPMPTIAAVTGHASAAGFILALSHDYVLMRKDRGVLYM-SEVDIglpLPDY-FMALLRAKIGS 153

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 213417737 206 RQALK--VLSGAlKLDSKNALNIGMVEEVLQSSDET 239
Cdd:PLN02267 154 PAARRdvLLRAA-KLTAEEAVEMGIVDSAHDSAEET 188
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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