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Conserved domains on  [gi|213513880|ref|NP_001134582|]
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Antimicrobial peptide NK-lysin precursor [Salmo salar]

Protein Classification

saposin domain-containing protein( domain architecture ID 12219188)

saposin domain-containing protein such as saposins, which are accessory proteins that aid in the degradation of sphingolipids by hydrolytic enzymes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SapB smart00741
Saposin (B) Domains; Present in multiple copies in prosaposin and in pulmonary ...
 44-117 8.69e-07

Saposin (B) Domains; Present in multiple copies in prosaposin and in pulmonary surfactant-associated protein B. In plant aspartic proteinases, a saposin domain is circularly permuted. This causes the prediction algorithm to predict two such domains, where only one is truly present.


:

Pssm-ID: 214797 [Multi-domain]  Cd Length: 76  Bit Score: 43.63  E-value: 8.69e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 213513880    44 TCWVCKWALKKVKESTSTSDSQETLKQKLLSVCDKVG-FLKSMCKGLMKKHLWVLIEELSTSDDVRTICVNIKAC 117
Cdd:smart00741   2 LCELCEFVVKQLENLLKDNKTEEEIKKALEKVCKKLPkSLSDQCKEFVDQYGPEIIDLLEQGLDPKDVCQKLGLC 76
 
Name Accession Description Interval E-value
SapB smart00741
Saposin (B) Domains; Present in multiple copies in prosaposin and in pulmonary ...
 44-117 8.69e-07

Saposin (B) Domains; Present in multiple copies in prosaposin and in pulmonary surfactant-associated protein B. In plant aspartic proteinases, a saposin domain is circularly permuted. This causes the prediction algorithm to predict two such domains, where only one is truly present.


Pssm-ID: 214797 [Multi-domain]  Cd Length: 76  Bit Score: 43.63  E-value: 8.69e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 213513880    44 TCWVCKWALKKVKESTSTSDSQETLKQKLLSVCDKVG-FLKSMCKGLMKKHLWVLIEELSTSDDVRTICVNIKAC 117
Cdd:smart00741   2 LCELCEFVVKQLENLLKDNKTEEEIKKALEKVCKKLPkSLSDQCKEFVDQYGPEIIDLLEQGLDPKDVCQKLGLC 76
 
Name Accession Description Interval E-value
SapB smart00741
Saposin (B) Domains; Present in multiple copies in prosaposin and in pulmonary ...
 44-117 8.69e-07

Saposin (B) Domains; Present in multiple copies in prosaposin and in pulmonary surfactant-associated protein B. In plant aspartic proteinases, a saposin domain is circularly permuted. This causes the prediction algorithm to predict two such domains, where only one is truly present.


Pssm-ID: 214797 [Multi-domain]  Cd Length: 76  Bit Score: 43.63  E-value: 8.69e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 213513880    44 TCWVCKWALKKVKESTSTSDSQETLKQKLLSVCDKVG-FLKSMCKGLMKKHLWVLIEELSTSDDVRTICVNIKAC 117
Cdd:smart00741   2 LCELCEFVVKQLENLLKDNKTEEEIKKALEKVCKKLPkSLSDQCKEFVDQYGPEIIDLLEQGLDPKDVCQKLGLC 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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