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Conserved domains on  [gi|256017249|ref|NP_001157706|]
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phospholipase DDHD2 isoform 2 [Homo sapiens]

Protein Classification

WWE domain-containing protein( domain architecture ID 10500679)

WWE domain-containing protein similar to Rattus norvegicus zinc finger CCCH-type antiviral protein 1, an antiviral protein which inhibits the replication of viruses by recruiting the cellular RNA degradation machineries to degrade the viral mRNAs

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WWE pfam02825
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
 43-112 1.90e-08

WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.


:

Pssm-ID: 460715 [Multi-domain]  Cd Length: 66  Bit Score: 49.60  E-value: 1.90e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256017249   43 HWFYCkiiDSKETWIPFNSEDSQQLEEAYSSGKGCNGRVVPTDGGRYDVHLGERMRYAVYwDELASEVRR 112
Cdd:pfam02825   1 VWEWE---DDNGGWHPYDPEVSSLIEEAYQKGKPSVDLSITTAGFPYTIDFKSMTQTNKD-TGTTRPVRR 66
 
Name Accession Description Interval E-value
WWE pfam02825
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
 43-112 1.90e-08

WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.


Pssm-ID: 460715 [Multi-domain]  Cd Length: 66  Bit Score: 49.60  E-value: 1.90e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256017249   43 HWFYCkiiDSKETWIPFNSEDSQQLEEAYSSGKGCNGRVVPTDGGRYDVHLGERMRYAVYwDELASEVRR 112
Cdd:pfam02825   1 VWEWE---DDNGGWHPYDPEVSSLIEEAYQKGKPSVDLSITTAGFPYTIDFKSMTQTNKD-TGTTRPVRR 66
 
Name Accession Description Interval E-value
WWE pfam02825
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
 43-112 1.90e-08

WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.


Pssm-ID: 460715 [Multi-domain]  Cd Length: 66  Bit Score: 49.60  E-value: 1.90e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256017249   43 HWFYCkiiDSKETWIPFNSEDSQQLEEAYSSGKGCNGRVVPTDGGRYDVHLGERMRYAVYwDELASEVRR 112
Cdd:pfam02825   1 VWEWE---DDNGGWHPYDPEVSSLIEEAYQKGKPSVDLSITTAGFPYTIDFKSMTQTNKD-TGTTRPVRR 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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