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Conserved domains on  [gi|258614029|ref|NP_001158251|]
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ataxin-3 isoform r [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SUIM_assoc pfam16619
Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on ...
 142-208 3.30e-22

Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on Ataxin 3 proteins that lies immediately C-terminal to the second UIM domain linking it to a third when present. The function is not known. It is rich in glutamine residues.


:

Pssm-ID: 465203  Cd Length: 60  Bit Score: 86.08  E-value: 3.30e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 258614029  142 NISQDMTQTSGTNLTSEELRKRREAYFEKQQQKQQQQqqqqqqgDLSGQSSHPCERPATSSGALGSD 208
Cdd:pfam16619   1 NISQDVPQTSGTSLTSEELRKRREAYFEKQQQQQQQL-------DQPGQSSHPHERPTTSSGALGSD 60
Josephin super family cl20229
Josephin;
9-42 5.23e-16

Josephin;


The actual alignment was detected with superfamily member pfam02099:

Pssm-ID: 460444  Cd Length: 154  Bit Score: 72.64  E-value: 5.23e-16
                          10        20        30
                  ....*....|....*....|....*....|....
gi 258614029    9 WFNLNSLLTGPELISDTYLALFLAQLQQEGYSIF 42
Cdd:pfam02099 121 WYNLNSLLKAPELISDTYLSAFLDQLEAEGYSIF 154
 
Name Accession Description Interval E-value
SUIM_assoc pfam16619
Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on ...
 142-208 3.30e-22

Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on Ataxin 3 proteins that lies immediately C-terminal to the second UIM domain linking it to a third when present. The function is not known. It is rich in glutamine residues.


Pssm-ID: 465203  Cd Length: 60  Bit Score: 86.08  E-value: 3.30e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 258614029  142 NISQDMTQTSGTNLTSEELRKRREAYFEKQQQKQQQQqqqqqqgDLSGQSSHPCERPATSSGALGSD 208
Cdd:pfam16619   1 NISQDVPQTSGTSLTSEELRKRREAYFEKQQQQQQQL-------DQPGQSSHPHERPTTSSGALGSD 60
Josephin pfam02099
Josephin;
9-42 5.23e-16

Josephin;


Pssm-ID: 460444  Cd Length: 154  Bit Score: 72.64  E-value: 5.23e-16
                          10        20        30
                  ....*....|....*....|....*....|....
gi 258614029    9 WFNLNSLLTGPELISDTYLALFLAQLQQEGYSIF 42
Cdd:pfam02099 121 WYNLNSLLKAPELISDTYLSAFLDQLEAEGYSIF 154
 
Name Accession Description Interval E-value
SUIM_assoc pfam16619
Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on ...
 142-208 3.30e-22

Unstructured region C-term to UIM in Ataxin3; SUIM_assoc is a natively unstructured region on Ataxin 3 proteins that lies immediately C-terminal to the second UIM domain linking it to a third when present. The function is not known. It is rich in glutamine residues.


Pssm-ID: 465203  Cd Length: 60  Bit Score: 86.08  E-value: 3.30e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 258614029  142 NISQDMTQTSGTNLTSEELRKRREAYFEKQQQKQQQQqqqqqqgDLSGQSSHPCERPATSSGALGSD 208
Cdd:pfam16619   1 NISQDVPQTSGTSLTSEELRKRREAYFEKQQQQQQQL-------DQPGQSSHPHERPTTSSGALGSD 60
Josephin pfam02099
Josephin;
9-42 5.23e-16

Josephin;


Pssm-ID: 460444  Cd Length: 154  Bit Score: 72.64  E-value: 5.23e-16
                          10        20        30
                  ....*....|....*....|....*....|....
gi 258614029    9 WFNLNSLLTGPELISDTYLALFLAQLQQEGYSIF 42
Cdd:pfam02099 121 WYNLNSLLKAPELISDTYLSAFLDQLEAEGYSIF 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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