|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
94-503 |
2.23e-61 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 205.41 E-value: 2.23e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 94 LSYEEQLKVKfaaqKKILQRLesyiqmLNGVSVTTAVPkserlsclLHPIIPSPVINGYRNKSTFSVnrGPDGNPKTVGF 173
Cdd:COG2265 81 LSYEAQLELK----QRVVREA------LERIGGLPEVE--------VEPIIGSPEPWGYRNRARLSV--RRTDGRLRLGF 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 174 YlgtwrdgnvvcvqsnhlknipEKHSqvaqyYEVFlrqsPLEPCLVFHEggywreltvrtnsqgHTMAIItfhpqklsqe 253
Cdd:COG2265 141 Y---------------------ARGS-----HELV----DIDECPLLDP---------------ALNALL---------- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 254 elhvqkEIVKEFFIRGPGAACGLTSLyfqestMTRCshqqspyqllfGEPYIFEELLSLKIRISPDAFFQINTAGAEMLY 333
Cdd:COG2265 166 ------PALRELLAELGARRGELRHL------VVRA-----------GRDYLTERLGGLTFRISPGSFFQVNPEQAEALY 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 334 RTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE 413
Cdd:COG2265 223 AAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELLWGGR 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 414 -DgqsiVAVVNPARAGLHYKVIQAIRNFRAiHTLVFVSCklhgestrnvielccppDPA------KKLLGEPFVLQQAVP 486
Cdd:COG2265 303 pD----VVVLDPPRAGAGPEVLEALAALGP-RRIVYVSC-----------------NPAtlardlALLVEGGYRLEKVQP 360
|
410
....*....|....*..
gi 269784680 487 VDLFPHTPHCELVLLFT 503
Cdd:COG2265 361 VDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
94-497 |
6.96e-31 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 124.16 E-value: 6.96e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 94 LSYEEQLKVKFAAQKKILQRLESYiqmlngvsvttavpKSERLSclLHPIIPSPVINgYRNKSTFSVNRGPDGNPKtVGF 173
Cdd:TIGR00479 72 LSYELQLRSKQQQVIALLERIGKF--------------VSEPIE--DVPTIGDDPWG-YRNKARLSLGRSPSGQLQ-AGF 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 174 Y-LGTWR--DGNVVCVQSNHL-------KNIPEKHSQVAQYYEVflrqsplepclvfhEGGYWRELTVRTNSQGHTMAI- 242
Cdd:TIGR00479 134 YqKGSHDivDVKQCPVQAPALnallpkvRAILENFGASRYLEHK--------------ELGQARHGVLRIGRHTGELSSv 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 243 -ITFHpqklsqEELHVQKEIVKEFFIRGP--GAAC-----GLTSLYFQESTMTrcshqqspyqlLFGEPYIFEELLSLKI 314
Cdd:TIGR00479 200 dRTAL------ERFPHKEELDLYLQPDSPdvKSICqninpEKTNVIFGEETEV-----------IAGEMPIYDKSGDLSF 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 315 RISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNS 394
Cdd:TIGR00479 263 TFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVGVEGVPESVEKAQQNAELNGIANV 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 395 EFHTGQAEKILPgllKSKEDGQSI-VAVVNPARAGLHYKVIQAIRNFRAIHtLVFVSCKlhgestrnvielccPPDPAKK 473
Cdd:TIGR00479 343 TFYHGTLETVLP---KQPWAGNGFdKVLLDPPRKGCAAGVLRTIIKLKPER-IVYVSCN--------------PATLARD 404
|
410 420
....*....|....*....|....*..
gi 269784680 474 ---LLGEPFVLQQAVPVDLFPHTPHCE 497
Cdd:TIGR00479 405 leaLCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
298-501 |
2.63e-18 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 85.69 E-value: 2.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 298 LLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRT----VGELtGVNSdtiLLDICCGTGVIGLSLAQHTSRVLGIE 373
Cdd:PRK03522 127 FLTEQQALPERFNGVPLFIRPQSFFQTNPAVAAQLYATardwVREL-PPRS---MWDLFCGVGGFGLHCATPGMQLTGIE 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 374 LLEQAVEDARWTAAFNGITNSEFH--------TGQAEKilPGLlkskedgqsivAVVNPARAGLHyKVIQAIRNFRAIHT 445
Cdd:PRK03522 203 ISAEAIACAKQSAAELGLTNVQFQaldstqfaTAQGEV--PDL-----------VLVNPPRRGIG-KELCDYLSQMAPRF 268
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 269784680 446 LVFVSCklhgestrNVIELccppdpAKKLLGEP-FVLQQAVPVDLFPHTPHCE-LVLL 501
Cdd:PRK03522 269 ILYSSC--------NAQTM------AKDLAHLPgYRIERVQLFDMFPHTAHYEvLTLL 312
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
297-504 |
5.39e-10 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 60.92 E-value: 5.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 297 QLLFGEPYIFEEL----LSLKIRISPDAFFQINTAGAEMLYRTVGELTGvNSDTILLDICCGTGVIGLSLAQHTSRVLGI 372
Cdd:pfam05958 151 KIVLDQDYVDETLpvagREFIYRQVENSFTQPNAAVNIKMLEWACDVTQ-GSKGDLLELYCGNGNFSLALARNFRKVLAT 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 373 ELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE----------DGQSIVAVVNPARAGLHYKVIQAIRNFRA 442
Cdd:pfam05958 230 EIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGVREfnrlkgidlkSYNCSTIFVDPPRAGLDPETLKLVQAYPR 309
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 269784680 443 IhtlVFVSCklhgestrNVIELCcppdpaKKL--LGEPFVLQQAVPVDLFPHTPHCELVLLFTR 504
Cdd:pfam05958 310 I---LYISC--------NPETLC------ANLeqLSKTHRVERFALFDQFPYTHHMECGVLLEK 356
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
348-441 |
1.15e-04 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 41.26 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 348 LLDICCGTGVIGLSLAQHTS-RVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPgllksKEDGQSIVAVVNPAR 426
Cdd:cd02440 2 VLDLGCGTGALALALASGPGaRVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPP-----EADESFDVIISDPPL 76
|
90
....*....|....*
gi 269784680 427 AGLHYKVIQAIRNFR 441
Cdd:cd02440 77 HHLVEDLARFLEEAR 91
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
94-503 |
2.23e-61 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 205.41 E-value: 2.23e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 94 LSYEEQLKVKfaaqKKILQRLesyiqmLNGVSVTTAVPkserlsclLHPIIPSPVINGYRNKSTFSVnrGPDGNPKTVGF 173
Cdd:COG2265 81 LSYEAQLELK----QRVVREA------LERIGGLPEVE--------VEPIIGSPEPWGYRNRARLSV--RRTDGRLRLGF 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 174 YlgtwrdgnvvcvqsnhlknipEKHSqvaqyYEVFlrqsPLEPCLVFHEggywreltvrtnsqgHTMAIItfhpqklsqe 253
Cdd:COG2265 141 Y---------------------ARGS-----HELV----DIDECPLLDP---------------ALNALL---------- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 254 elhvqkEIVKEFFIRGPGAACGLTSLyfqestMTRCshqqspyqllfGEPYIFEELLSLKIRISPDAFFQINTAGAEMLY 333
Cdd:COG2265 166 ------PALRELLAELGARRGELRHL------VVRA-----------GRDYLTERLGGLTFRISPGSFFQVNPEQAEALY 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 334 RTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE 413
Cdd:COG2265 223 AAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELLWGGR 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 414 -DgqsiVAVVNPARAGLHYKVIQAIRNFRAiHTLVFVSCklhgestrnvielccppDPA------KKLLGEPFVLQQAVP 486
Cdd:COG2265 303 pD----VVVLDPPRAGAGPEVLEALAALGP-RRIVYVSC-----------------NPAtlardlALLVEGGYRLEKVQP 360
|
410
....*....|....*..
gi 269784680 487 VDLFPHTPHCELVLLFT 503
Cdd:COG2265 361 VDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
94-497 |
6.96e-31 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 124.16 E-value: 6.96e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 94 LSYEEQLKVKFAAQKKILQRLESYiqmlngvsvttavpKSERLSclLHPIIPSPVINgYRNKSTFSVNRGPDGNPKtVGF 173
Cdd:TIGR00479 72 LSYELQLRSKQQQVIALLERIGKF--------------VSEPIE--DVPTIGDDPWG-YRNKARLSLGRSPSGQLQ-AGF 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 174 Y-LGTWR--DGNVVCVQSNHL-------KNIPEKHSQVAQYYEVflrqsplepclvfhEGGYWRELTVRTNSQGHTMAI- 242
Cdd:TIGR00479 134 YqKGSHDivDVKQCPVQAPALnallpkvRAILENFGASRYLEHK--------------ELGQARHGVLRIGRHTGELSSv 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 243 -ITFHpqklsqEELHVQKEIVKEFFIRGP--GAAC-----GLTSLYFQESTMTrcshqqspyqlLFGEPYIFEELLSLKI 314
Cdd:TIGR00479 200 dRTAL------ERFPHKEELDLYLQPDSPdvKSICqninpEKTNVIFGEETEV-----------IAGEMPIYDKSGDLSF 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 315 RISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNS 394
Cdd:TIGR00479 263 TFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVGVEGVPESVEKAQQNAELNGIANV 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 395 EFHTGQAEKILPgllKSKEDGQSI-VAVVNPARAGLHYKVIQAIRNFRAIHtLVFVSCKlhgestrnvielccPPDPAKK 473
Cdd:TIGR00479 343 TFYHGTLETVLP---KQPWAGNGFdKVLLDPPRKGCAAGVLRTIIKLKPER-IVYVSCN--------------PATLARD 404
|
410 420
....*....|....*....|....*..
gi 269784680 474 ---LLGEPFVLQQAVPVDLFPHTPHCE 497
Cdd:TIGR00479 405 leaLCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
298-501 |
2.63e-18 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 85.69 E-value: 2.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 298 LLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRT----VGELtGVNSdtiLLDICCGTGVIGLSLAQHTSRVLGIE 373
Cdd:PRK03522 127 FLTEQQALPERFNGVPLFIRPQSFFQTNPAVAAQLYATardwVREL-PPRS---MWDLFCGVGGFGLHCATPGMQLTGIE 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 374 LLEQAVEDARWTAAFNGITNSEFH--------TGQAEKilPGLlkskedgqsivAVVNPARAGLHyKVIQAIRNFRAIHT 445
Cdd:PRK03522 203 ISAEAIACAKQSAAELGLTNVQFQaldstqfaTAQGEV--PDL-----------VLVNPPRRGIG-KELCDYLSQMAPRF 268
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 269784680 446 LVFVSCklhgestrNVIELccppdpAKKLLGEP-FVLQQAVPVDLFPHTPHCE-LVLL 501
Cdd:PRK03522 269 ILYSSC--------NAQTM------AKDLAHLPgYRIERVQLFDMFPHTAHYEvLTLL 312
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
292-504 |
1.58e-11 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 66.33 E-value: 1.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 292 QQSPYQLLFGepyifeellsLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLG 371
Cdd:PRK13168 255 QLSYYLPEFG----------LRLAFSPRDFIQVNAQVNQKMVARALEWLDPQPGDRVLDLFCGLGNFTLPLARQAAEVVG 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 372 IELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKedgQSIVAV-VNPARAGLhYKVIQAIRNFRAIhTLVFVS 450
Cdd:PRK13168 325 VEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDQPWAL---GGFDKVlLDPPRAGA-AEVMQALAKLGPK-RIVYVS 399
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 451 CklhgestrnvielccppDPA------KKLLGEPFVLQQAVPVDLFPHTPHCELVLLFTR 504
Cdd:PRK13168 400 C-----------------NPAtlardaGVLVEAGYRLKRAGMLDMFPHTGHVESMALFER 442
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
297-504 |
5.39e-10 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 60.92 E-value: 5.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 297 QLLFGEPYIFEEL----LSLKIRISPDAFFQINTAGAEMLYRTVGELTGvNSDTILLDICCGTGVIGLSLAQHTSRVLGI 372
Cdd:pfam05958 151 KIVLDQDYVDETLpvagREFIYRQVENSFTQPNAAVNIKMLEWACDVTQ-GSKGDLLELYCGNGNFSLALARNFRKVLAT 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 373 ELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE----------DGQSIVAVVNPARAGLHYKVIQAIRNFRA 442
Cdd:pfam05958 230 EIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGVREfnrlkgidlkSYNCSTIFVDPPRAGLDPETLKLVQAYPR 309
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 269784680 443 IhtlVFVSCklhgestrNVIELCcppdpaKKL--LGEPFVLQQAVPVDLFPHTPHCELVLLFTR 504
Cdd:pfam05958 310 I---LYISC--------NPETLC------ANLeqLSKTHRVERFALFDQFPYTHHMECGVLLEK 356
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
342-393 |
6.24e-08 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 53.61 E-value: 6.24e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 269784680 342 VNSDTILL-------------DICCGTGVIGLSLAQHTS--RVLGIELLEQAVEDARWTAAFNGITN 393
Cdd:COG4123 22 FGTDAVLLaafapvkkggrvlDLGTGTGVIALMLAQRSPgaRITGVEIQPEAAELARRNVALNGLED 88
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
348-399 |
8.40e-08 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 52.50 E-value: 8.40e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 269784680 348 LLDICCGTGVIGLSLAQHT--SRVLGIELLEQAVEDARWTAAFNGITNSEFHTG 399
Cdd:COG2813 53 VLDLGCGYGVIGLALAKRNpeARVTLVDVNARAVELARANAAANGLENVEVLWS 106
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
298-501 |
5.24e-07 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 51.75 E-value: 5.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 298 LLFGEPYIFEEL----LSLKIRISPDAFFQINTAGAE-MLYRTVGELTGVNSDtiLLDICCGTGVIGLSLAQHTSRVLGI 372
Cdd:PRK05031 157 IVLDQDYVDERLpvagREFIYRQVENSFTQPNAAVNEkMLEWALDATKGSKGD--LLELYCGNGNFTLALARNFRRVLAT 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 373 ELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKE------------DGQSIvaVVNPARAGLHYKVIQAIRNF 440
Cdd:PRK05031 235 EISKPSVAAAQYNIAANGIDNVQIIRMSAEEFTQAMNGVREfnrlkgidlksyNFSTI--FVDPPRAGLDDETLKLVQAY 312
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 269784680 441 RAIhtlVFVSCK---LHgestRNVIELCCPPDPAKkllgepFVLqqavpVDLFPHTPHCEL-VLL 501
Cdd:PRK05031 313 ERI---LYISCNpetLC----ENLETLSQTHKVER------FAL-----FDQFPYTHHMECgVLL 359
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
349-404 |
1.60e-06 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 46.40 E-value: 1.60e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 269784680 349 LDICCGTGVIGLSLAQHT-SRVLGIELLEQAVEDARWTAAFNGItNSEFHTGQAEKI 404
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGgARVTGVDLSPEMLERARERAAEAGL-NVEFVQGDAEDL 57
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
332-404 |
3.01e-06 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 46.91 E-value: 3.01e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 269784680 332 LYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGItNSEFHTGQAEKI 404
Cdd:COG2226 10 GREALLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAEDL 81
|
|
| HemK |
COG2890 |
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ... |
301-399 |
6.60e-06 |
|
Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442135 [Multi-domain] Cd Length: 282 Bit Score: 47.84 E-value: 6.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 301 GEP--YI--FEELLSLKIRISPDAFfqI---NTagaEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQH--TSRVLG 371
Cdd:COG2890 67 GEPlaYIlgEAEFYGLEFKVDPGVL--IprpET---EELVELALALLPAGAPPRVLDLGTGSGAIALALAKErpDARVTA 141
|
90 100
....*....|....*....|....*....
gi 269784680 372 IELLEQAVEDARWTAAFNGITNS-EFHTG 399
Cdd:COG2890 142 VDISPDALAVARRNAERLGLEDRvRFLQG 170
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
343-404 |
1.01e-05 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 45.49 E-value: 1.01e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 269784680 343 NSDTILLDICCGTGVIGLSLAQHT---SRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKI 404
Cdd:pfam13847 2 DKGMRVLDLGCGTGHLSFELAEELgpnAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEEL 66
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
349-399 |
2.08e-05 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 46.31 E-value: 2.08e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 269784680 349 LDICCGTGVIGLSLAQH--TSRVLGIELLEQAVEDARWTAAFNGITNSEFHTG 399
Cdd:PRK09328 113 LDLGTGSGAIALALAKErpDAEVTAVDISPEALAVARRNAKHGLGARVEFLQG 165
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
348-404 |
3.66e-05 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 43.47 E-value: 3.66e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 269784680 348 LLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGItnsEFHTGQAEKI 404
Cdd:COG2227 28 VLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAELNV---DFVQGDLEDL 81
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
349-406 |
5.71e-05 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 44.14 E-value: 5.71e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 269784680 349 LDICCGTGVIGLSLAQHT-SRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILP 406
Cdd:COG0500 31 LDLGCGTGRNLLALAARFgGRVIGIDLSPEAIALARARAAKAGLGNVEFLVADLAELDP 89
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
348-441 |
1.15e-04 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 41.26 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 348 LLDICCGTGVIGLSLAQHTS-RVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPgllksKEDGQSIVAVVNPAR 426
Cdd:cd02440 2 VLDLGCGTGALALALASGPGaRVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPP-----EADESFDVIISDPPL 76
|
90
....*....|....*
gi 269784680 427 AGLHYKVIQAIRNFR 441
Cdd:cd02440 77 HHLVEDLARFLEEAR 91
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
349-437 |
1.19e-04 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 42.58 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 349 LDICCGTGVIGLSLAQHTSRVlGIELLE---QAVEDARWTAAFNGITNSEFHTGQaekilpgLLKSKEDGQSIVAVVNPA 425
Cdd:pfam05175 36 LDLGCGAGVLGAALAKESPDA-ELTMVDinaRALESARENLAANGLENGEVVASD-------VYSGVEDGKFDLIISNPP 107
|
90
....*....|....*
gi 269784680 426 -RAGLH--YKVIQAI 437
Cdd:pfam05175 108 fHAGLAttYNVAQRF 122
|
|
| PrmA |
pfam06325 |
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ... |
342-420 |
1.69e-04 |
|
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.
Pssm-ID: 428888 [Multi-domain] Cd Length: 294 Bit Score: 43.41 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 269784680 342 VNSDTILLDICCGTGVigLSLAQH---TSRVLGIELLEQAVEDARWTAAFNGITNsefhtgQAEKILPG-LLKSKEDGqs 417
Cdd:pfam06325 159 VKPGESVLDVGCGSGI--LAIAALklgAKKVVGVDIDPVAVRAAKENAELNGVEA------RLEVYLPGdLPKEKADV-- 228
|
...
gi 269784680 418 IVA 420
Cdd:pfam06325 229 VVA 231
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
349-383 |
2.01e-04 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 42.29 E-value: 2.01e-04
10 20 30
....*....|....*....|....*....|....*
gi 269784680 349 LDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDAR 383
Cdd:COG4976 51 LDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAR 85
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
334-404 |
1.44e-03 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 39.55 E-value: 1.44e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 269784680 334 RTVGELTGVNSDTILLDICCGTGVI---GLSLAqhtSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKI 404
Cdd:COG1041 16 RALVNLAGAKEGDTVLDPFCGTGTIlieAGLLG---RRVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARDL 86
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
349-393 |
2.59e-03 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 39.11 E-value: 2.59e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 269784680 349 LDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITN 393
Cdd:PRK14968 28 LEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRN 72
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
349-407 |
3.55e-03 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 37.11 E-value: 3.55e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 269784680 349 LDICCGTGVIGLSLAQHT--SRVLGIELLEQAVEDARwtAAFNGITnseFHTGQAEKILPG 407
Cdd:COG4106 6 LDLGCGTGRLTALLAERFpgARVTGVDLSPEMLARAR--ARLPNVR---FVVADLRDLDPP 61
|
|
| |
