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Conserved domains on  [gi|289577065|ref|NP_001166163|]
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zinc finger protein 573 isoform 2 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
72-433 3.93e-13

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 71.65  E-value: 3.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065  72 RPYECKECGKNFRSGYQLTLHQRFHTGEKPYECT--ECGKNFRSGYQLTVHQRFHTGEKTYECRQ--------------- 134
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSKslplsnskassssls 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 135 -CGKAFIYASHIVQH-------------ERIHTGGKPYECQECGRAFSQG----------------------GHLRIHQR 178
Cdd:COG5048  112 sSSSNSNDNNLLSSHslppssrdpqlpdLLSISNLRNNPLPGNNSSSVNTpqsnslhpplpanslskdpssnLSLLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 179 VHTGEKPYKCKECGKTFSRRSNlveHGQFHTDEKPYICEKCGKAFRRGHQLTVHQRVHTGKKPYECKECGKGY------- 251
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPS---SSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrsslpta 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 252 --TTASYFLLHQRIHKG-GKPYECKECKKTFTLYRNLTRHQN--IHTGEKLfeckqcgktyttgsklfqhqkthtgeKPY 326
Cdd:COG5048  269 ssQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGESL--------------------------KPF 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 327 ECKE--CGKAFSLYGYLKQHQKIHTGMKHFECKECKKTFTLYRNLT-------RHQNIHTGKKLFEC--QECGKAYSTGS 395
Cdd:COG5048  323 SCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETlsNSCIRNFKRDS 402

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 289577065 396 NLIQHRKTHTGEKP--YKCKECGKTFSLHGYLNQHQKIHT 433
Cdd:COG5048  403 NLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
354-576 8.32e-05

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.46  E-value: 8.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 354 FECKECKKTFTLYRNLTRHQNIHTGKKLFEC--QECGKAYSTGSNLIQHRKTHTGEKPYKCK----------------EC 415
Cdd:COG5048   34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkslplsnskasssslsSS 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 416 GKTFSLHGYLNQH---QKIHTGMKPYECKVC--------------------------------RKTFTFYRNLTLHQSIH 460
Cdd:COG5048  114 SSNSNDNNLLSSHslpPSSRDPQLPDLLSISnlrnnplpgnnsssvntpqsnslhpplpanslSKDPSSNLSLLISSNVS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 461 TDEKPFECKECGKTFRR-------------SSHLTAHQSIHADKKPY---------------ECKECGKAFKMYGYLTQH 512
Cdd:COG5048  194 TSIPSSSENSPLSSSYSipssssdqnlensSSSLPLTTNSQLSPKSLlsqspsslsssdsssSASESPRSSLPTASSQSS 273

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 289577065 513 QKIHTG-------GKPYECKECGKAFSRASNLVQHER--IHTGE--KPYVC--KQCGKTFRYGSALKAHQRIHRSIK 576
Cdd:COG5048  274 SPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSIS 350
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
72-433 3.93e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 71.65  E-value: 3.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065  72 RPYECKECGKNFRSGYQLTLHQRFHTGEKPYECT--ECGKNFRSGYQLTVHQRFHTGEKTYECRQ--------------- 134
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSKslplsnskassssls 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 135 -CGKAFIYASHIVQH-------------ERIHTGGKPYECQECGRAFSQG----------------------GHLRIHQR 178
Cdd:COG5048  112 sSSSNSNDNNLLSSHslppssrdpqlpdLLSISNLRNNPLPGNNSSSVNTpqsnslhpplpanslskdpssnLSLLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 179 VHTGEKPYKCKECGKTFSRRSNlveHGQFHTDEKPYICEKCGKAFRRGHQLTVHQRVHTGKKPYECKECGKGY------- 251
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPS---SSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrsslpta 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 252 --TTASYFLLHQRIHKG-GKPYECKECKKTFTLYRNLTRHQN--IHTGEKLfeckqcgktyttgsklfqhqkthtgeKPY 326
Cdd:COG5048  269 ssQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGESL--------------------------KPF 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 327 ECKE--CGKAFSLYGYLKQHQKIHTGMKHFECKECKKTFTLYRNLT-------RHQNIHTGKKLFEC--QECGKAYSTGS 395
Cdd:COG5048  323 SCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETlsNSCIRNFKRDS 402

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 289577065 396 NLIQHRKTHTGEKP--YKCKECGKTFSLHGYLNQHQKIHT 433
Cdd:COG5048  403 NLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
354-576 8.32e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.46  E-value: 8.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 354 FECKECKKTFTLYRNLTRHQNIHTGKKLFEC--QECGKAYSTGSNLIQHRKTHTGEKPYKCK----------------EC 415
Cdd:COG5048   34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkslplsnskasssslsSS 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 416 GKTFSLHGYLNQH---QKIHTGMKPYECKVC--------------------------------RKTFTFYRNLTLHQSIH 460
Cdd:COG5048  114 SSNSNDNNLLSSHslpPSSRDPQLPDLLSISnlrnnplpgnnsssvntpqsnslhpplpanslSKDPSSNLSLLISSNVS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 461 TDEKPFECKECGKTFRR-------------SSHLTAHQSIHADKKPY---------------ECKECGKAFKMYGYLTQH 512
Cdd:COG5048  194 TSIPSSSENSPLSSSYSipssssdqnlensSSSLPLTTNSQLSPKSLlsqspsslsssdsssSASESPRSSLPTASSQSS 273

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 289577065 513 QKIHTG-------GKPYECKECGKAFSRASNLVQHER--IHTGE--KPYVC--KQCGKTFRYGSALKAHQRIHRSIK 576
Cdd:COG5048  274 SPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSIS 350
zf-H2C2_2 pfam13465
Zinc-finger double domain;
172-197 1.14e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.14e-03
                          10        20
                  ....*....|....*....|....*.
gi 289577065  172 HLRIHQRVHTGEKPYKCKECGKTFSR 197
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
536-561 1.70e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.70e-03
                          10        20
                  ....*....|....*....|....*.
gi 289577065  536 NLVQHERIHTGEKPYVCKQCGKTFRY 561
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
72-433 3.93e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 71.65  E-value: 3.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065  72 RPYECKECGKNFRSGYQLTLHQRFHTGEKPYECT--ECGKNFRSGYQLTVHQRFHTGEKTYECRQ--------------- 134
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSKslplsnskassssls 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 135 -CGKAFIYASHIVQH-------------ERIHTGGKPYECQECGRAFSQG----------------------GHLRIHQR 178
Cdd:COG5048  112 sSSSNSNDNNLLSSHslppssrdpqlpdLLSISNLRNNPLPGNNSSSVNTpqsnslhpplpanslskdpssnLSLLISSN 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 179 VHTGEKPYKCKECGKTFSRRSNlveHGQFHTDEKPYICEKCGKAFRRGHQLTVHQRVHTGKKPYECKECGKGY------- 251
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPS---SSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrsslpta 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 252 --TTASYFLLHQRIHKG-GKPYECKECKKTFTLYRNLTRHQN--IHTGEKLfeckqcgktyttgsklfqhqkthtgeKPY 326
Cdd:COG5048  269 ssQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGESL--------------------------KPF 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 327 ECKE--CGKAFSLYGYLKQHQKIHTGMKHFECKECKKTFTLYRNLT-------RHQNIHTGKKLFEC--QECGKAYSTGS 395
Cdd:COG5048  323 SCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETlsNSCIRNFKRDS 402

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 289577065 396 NLIQHRKTHTGEKP--YKCKECGKTFSLHGYLNQHQKIHT 433
Cdd:COG5048  403 NLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
268-572 1.18e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 67.03  E-value: 1.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 268 KPYECKECKKTFTLYRNLTRHQNIHTGEKLFEC--KQCGKTYTTGSKLFQHQKTHTGEKPYECK---------------- 329
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkslplsnskassssls 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 330 ECGKAFSLYGYLKQH---QKIHTGMKHFECkeckkTFTLYRNLTRHQNIHTGKKLFECQE----------CGKAYSTGSN 396
Cdd:COG5048  112 SSSSNSNDNNLLSSHslpPSSRDPQLPDLL-----SISNLRNNPLPGNNSSSVNTPQSNSlhpplpanslSKDPSSNLSL 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 397 LIQHRKTHTGEKPYKCKECGKTFSLHGyLNQHQKIHTGMKPYECKVCRKTFTFYRNLTLHQSIHTDEKPFECKECGKTFR 476
Cdd:COG5048  187 LISSNVSTSIPSSSENSPLSSSYSIPS-SSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 477 RSSHLTAHQSIHAD-------KKPYECKECGKAFKMYGYLTQHQ--KIHTG--GKPYECKE--CGKAFSRASNLVQHERI 543
Cdd:COG5048  266 PTASSQSSSPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLrsVNHSGesLKPFSCPYslCGKLFSRNDALKRHILL 345

                        330       340       350
                 ....*....|....*....|....*....|.
gi 289577065 544 HTGEKPYVCK--QCGKTFRYGSALKAHQRIH 572
Cdd:COG5048  346 HTSISPAKEKllNSSSKFSPLLNNEPPQSLQ 376
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
156-540 5.93e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 64.72  E-value: 5.93e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 156 KPYECQECGRAFSQGGHLRIHQRVHTGEKPYKC--KECGKTFSRRSNLVEHGQFHT------------------------ 209
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHnnpsdlnskslplsnskassssls 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 210 -----DEKPYICEKCGKAFRRGHQLTVHQRVHTGKKPYECKECGKGYT-TASYFLLHQRIHKggkpyecKECKKTFTLYR 283
Cdd:COG5048  112 ssssnSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVnTPQSNSLHPPLPA-------NSLSKDPSSNL 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 284 NLTRHQNIHTGEKLFECKQCGKTYTTGSKLFQHQKTHTGEKPYECKECGKAF--SLYGYLKQHQKIHTgmKHFECKECKK 361
Cdd:COG5048  185 SLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSpkSLLSQSPSSLSSSD--SSSSASESPR 262

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 362 TFTLYRNLTRHQNIHTG-------KKLFECQECGKAYSTGSNLIQHRKT--HTGE--KPYKCKE--CGKTFSLHGYLNQH 428
Cdd:COG5048  263 SSLPTASSQSSSPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 429 QKIHTGMKPYECKVCRKTFTFYRNLT-------LHQSIHTDEKPFEC--KECGKTFRRSSHLTAHQSIHADKKPYECK-- 497
Cdd:COG5048  343 ILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|...
gi 289577065 498 ECGKAFKMYGYLTQHQKIHTGGKPYECkECGKAFSRASNLVQH 540
Cdd:COG5048  423 PCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
354-576 8.32e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.46  E-value: 8.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 354 FECKECKKTFTLYRNLTRHQNIHTGKKLFEC--QECGKAYSTGSNLIQHRKTHTGEKPYKCK----------------EC 415
Cdd:COG5048   34 DSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSkslplsnskasssslsSS 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 416 GKTFSLHGYLNQH---QKIHTGMKPYECKVC--------------------------------RKTFTFYRNLTLHQSIH 460
Cdd:COG5048  114 SSNSNDNNLLSSHslpPSSRDPQLPDLLSISnlrnnplpgnnsssvntpqsnslhpplpanslSKDPSSNLSLLISSNVS 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 461 TDEKPFECKECGKTFRR-------------SSHLTAHQSIHADKKPY---------------ECKECGKAFKMYGYLTQH 512
Cdd:COG5048  194 TSIPSSSENSPLSSSYSipssssdqnlensSSSLPLTTNSQLSPKSLlsqspsslsssdsssSASESPRSSLPTASSQSS 273

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 289577065 513 QKIHTG-------GKPYECKECGKAFSRASNLVQHER--IHTGE--KPYVC--KQCGKTFRYGSALKAHQRIHRSIK 576
Cdd:COG5048  274 SPNESDsssekgfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSIS 350
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 434-514 3.54e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.17  E-value: 3.54e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289577065 434 GMKPYECKV--CRKTFTF-----YRNLTLHQSIHTDEKPFECKecgktfrrsshltaHQSIHADKKPYECKECGKAFKMY 506
Cdd:COG5189  346 DGKPYKCPVegCNKKYKNqnglkYHMLHGHQNQKLHENPSPEK--------------MNIFSAKDKPYRCEVCDKRYKNL 411


                 ....*...
gi 289577065 507 GYLTQHQK 514
Cdd:COG5189  412 NGLKYHRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
172-197 1.14e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.14e-03
                          10        20
                  ....*....|....*....|....*.
gi 289577065  172 HLRIHQRVHTGEKPYKCKECGKTFSR 197
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
536-561 1.70e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.70e-03
                          10        20
                  ....*....|....*....|....*.
gi 289577065  536 NLVQHERIHTGEKPYVCKQCGKTFRY 561
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
396-420 2.07e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.07e-03
                          10        20
                  ....*....|....*....|....*
gi 289577065  396 NLIQHRKTHTGEKPYKCKECGKTFS 420
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
452-524 2.88e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.45  E-value: 2.88e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 289577065 452 NLTLHQSIHTDEKPFECKECGKTFRRSSHLTAHQSIHADKKPYEC--KECGKAFKMYGYLTQHQKIHTGGKPYEC 524
Cdd:COG5048   20 PKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLN 94
zf-H2C2_2 pfam13465
Zinc-finger double domain;
313-336 3.84e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.84e-03
                          10        20
                  ....*....|....*....|....
gi 289577065  313 LFQHQKTHTGEKPYECKECGKAFS 336
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
508-533 6.46e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 6.46e-03
                          10        20
                  ....*....|....*....|....*.
gi 289577065  508 YLTQHQKIHTGGKPYECKECGKAFSR 533
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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