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Conserved domains on  [gi|291219932|ref|NP_001167461|]
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transmembrane protein 216 isoform 2 [Homo sapiens]

Protein Classification

transmembrane 17 domain-containing protein( domain architecture ID 10561172)

transmembrane 17 domain-containing protein similar to Homo sapien transmebrane 17 protein, which is part of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Transmemb_17 pfam09799
Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved ...
 22-128 1.26e-24

Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved from nematodes to humans. It is predicted to be a transmembrane region but its function is not known.


:

Pssm-ID: 462907  Cd Length: 107  Bit Score: 90.72  E-value: 1.26e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291219932   22 ILFFLNGWYNATYFLLELFIFLYKGVLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLSISVALTFPSAM 101
Cdd:pfam09799   1 MLLYFNSYYFPLWFLAELLLLIYKGINLPYPGNYLALDVVLLVLLAILEVLRLYLGYKGNLTEKVPPLAAFLLLTLPSQL 80

                          90       100
                  ....*....|....*....|....*..
gi 291219932  102 MASYYLLLQTYVLRLEAIMNGILLFFC 128
Cdd:pfam09799  81 PLVYLLLLQTYVLRLEYILNAILLALL 107
 
Name Accession Description Interval E-value
Transmemb_17 pfam09799
Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved ...
 22-128 1.26e-24

Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved from nematodes to humans. It is predicted to be a transmembrane region but its function is not known.


Pssm-ID: 462907  Cd Length: 107  Bit Score: 90.72  E-value: 1.26e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291219932   22 ILFFLNGWYNATYFLLELFIFLYKGVLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLSISVALTFPSAM 101
Cdd:pfam09799   1 MLLYFNSYYFPLWFLAELLLLIYKGINLPYPGNYLALDVVLLVLLAILEVLRLYLGYKGNLTEKVPPLAAFLLLTLPSQL 80

                          90       100
                  ....*....|....*....|....*..
gi 291219932  102 MASYYLLLQTYVLRLEAIMNGILLFFC 128
Cdd:pfam09799  81 PLVYLLLLQTYVLRLEYILNAILLALL 107
 
Name Accession Description Interval E-value
Transmemb_17 pfam09799
Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved ...
 22-128 1.26e-24

Predicted membrane protein; This is a 100 amino acid region of a family of proteins conserved from nematodes to humans. It is predicted to be a transmembrane region but its function is not known.


Pssm-ID: 462907  Cd Length: 107  Bit Score: 90.72  E-value: 1.26e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291219932   22 ILFFLNGWYNATYFLLELFIFLYKGVLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLSISVALTFPSAM 101
Cdd:pfam09799   1 MLLYFNSYYFPLWFLAELLLLIYKGINLPYPGNYLALDVVLLVLLAILEVLRLYLGYKGNLTEKVPPLAAFLLLTLPSQL 80

                          90       100
                  ....*....|....*....|....*..
gi 291219932  102 MASYYLLLQTYVLRLEAIMNGILLFFC 128
Cdd:pfam09799  81 PLVYLLLLQTYVLRLEYILNAILLALL 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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