NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|291490690|ref|NP_001167561|]
View 

solute carrier family 4 member 11 isoform 1 [Homo sapiens]

Protein Classification

sodium bicarbonate transporter family protein( domain architecture ID 10469757)

sodium bicarbonate transporter family protein similar to Homo sapiens sodium bicarbonate transporter-like protein 11 that plays an important role in sodium-mediated fluid transport in different organs

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
HCO3_cotransp pfam00955
HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange ...
368-861 0e+00

HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange CL-/HCO3-. This family also includes cotransporters of Na+/HCO3-.


:

Pssm-ID: 460009  Cd Length: 497  Bit Score: 571.78  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  368 PFGkGIREDIARRFPLYPLDFTDGIigknkaVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLL 447
Cdd:pfam00955   2 LFG-GLINDIKRRYPHYLSDFTDAL------NLQCLASIIFLYFACLSPAITFGGLLGDATDGYIGVSESILSQAIGGII 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  448 YALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISI 527
Cdd:pfam00955  75 FALFAGQPLTILGSTGPLLVFEKILFKFCKDNGLDYLSFRAWIGLWLAFFLLLLVAFDASFLVRYITRFTEEIFALLISL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  528 TFVLDAVKGTVKIFwKYYYGHYLDDYHTKRTSSLVSLSglGASLNASLHTALNASFLASPTE---------LPSATHSGQ 598
Cdd:pfam00955 155 IFIYEAFKKLIKIF-KKYPLYLNYDCTCVPPSSNNTTN--STLSLSTESSSINWSSLLTNSEctesyggtlVGSGCGYVP 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  599 ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEM----SKFRYNPSESPFAM 674
Cdd:pfam00955 232 DTALLSLILFLGTFWLAYFLKQFKNSPFFPTKVRRLISDFAVPIAILIMVLVDYFLGVYTPKlqvpSGFKPTRPDRGWII 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  675 AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPL 754
Cdd:pfam00955 312 NPFGKNPWWLILAAILPALLVTILIFMDQQITAVIVNRKENKLKKGSGYHLDLFVVAILNGICSLFGLPWMVAATVRSIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  755 HVRALALVEERVENGhIYDTIVNVKETRLTSLGAsVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVAL 834
Cdd:pfam00955 392 HVNSLKVESECVAPG-EKPKILGVREQRVTGLLV-FILIGLSVFMTPVLKLIPMPVLYGVFLYMGVTSLSGIQFFDRILL 469
                         490       500
                  ....*....|....*....|....*..
gi 291490690  835 LLKEQTAYPPTHYIRRVPQRKIHYFTG 861
Cdd:pfam00955 470 LFMPQKHQPDTHYLRHVPLRKVHLFTL 496
PtsN super family cl43506
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
249-327 7.55e-05

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG1762:

Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 43.69  E-value: 7.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690 249 KALQKRHVCISRLVRPQNWGENSCE-VRFVILVLAPPKmkSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH 327
Cdd:COG1762   71 EGVKKPGIAVARLKEPVDFGAMDGEpVDLVFLLAAPED--DSEEHLKLLAELARLLSDEEFREKLLNAKSPEEILELLKE 148
 
Name Accession Description Interval E-value
HCO3_cotransp pfam00955
HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange ...
368-861 0e+00

HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange CL-/HCO3-. This family also includes cotransporters of Na+/HCO3-.


Pssm-ID: 460009  Cd Length: 497  Bit Score: 571.78  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  368 PFGkGIREDIARRFPLYPLDFTDGIigknkaVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLL 447
Cdd:pfam00955   2 LFG-GLINDIKRRYPHYLSDFTDAL------NLQCLASIIFLYFACLSPAITFGGLLGDATDGYIGVSESILSQAIGGII 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  448 YALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISI 527
Cdd:pfam00955  75 FALFAGQPLTILGSTGPLLVFEKILFKFCKDNGLDYLSFRAWIGLWLAFFLLLLVAFDASFLVRYITRFTEEIFALLISL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  528 TFVLDAVKGTVKIFwKYYYGHYLDDYHTKRTSSLVSLSglGASLNASLHTALNASFLASPTE---------LPSATHSGQ 598
Cdd:pfam00955 155 IFIYEAFKKLIKIF-KKYPLYLNYDCTCVPPSSNNTTN--STLSLSTESSSINWSSLLTNSEctesyggtlVGSGCGYVP 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  599 ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEM----SKFRYNPSESPFAM 674
Cdd:pfam00955 232 DTALLSLILFLGTFWLAYFLKQFKNSPFFPTKVRRLISDFAVPIAILIMVLVDYFLGVYTPKlqvpSGFKPTRPDRGWII 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  675 AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPL 754
Cdd:pfam00955 312 NPFGKNPWWLILAAILPALLVTILIFMDQQITAVIVNRKENKLKKGSGYHLDLFVVAILNGICSLFGLPWMVAATVRSIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  755 HVRALALVEERVENGhIYDTIVNVKETRLTSLGAsVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVAL 834
Cdd:pfam00955 392 HVNSLKVESECVAPG-EKPKILGVREQRVTGLLV-FILIGLSVFMTPVLKLIPMPVLYGVFLYMGVTSLSGIQFFDRILL 469
                         490       500
                  ....*....|....*....|....*..
gi 291490690  835 LLKEQTAYPPTHYIRRVPQRKIHYFTG 861
Cdd:pfam00955 470 LFMPQKHQPDTHYLRHVPLRKVHLFTL 496
ae TIGR00834
anion exchange protein; The Anion Exchanger (AE) Family (TC 2.A.31)Characterized protein ...
274-915 2.53e-89

anion exchange protein; The Anion Exchanger (AE) Family (TC 2.A.31)Characterized protein members of the AE family are found only in animals.They preferentially catalyze anion exchange (antiport) reactions, typically acting as HCO3-:Cl- antiporters, but also transporting a range of other inorganic and organic anions. Additionally, renal Na+:HCO3- cotransporters have been found to be members of the AE family. They catalyze the reabsorption of HCO3- in the renal proximal tubule. [Transport and binding proteins, Anions]


Pssm-ID: 273290 [Multi-domain]  Cd Length: 900  Bit Score: 304.00  E-value: 2.53e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  274 VRFVILVLAP--PKMKSTktamEVARTFATMFSDIAF---------RQKLLETRTE---------------EEFKEALVH 327
Cdd:TIGR00834 220 VRFLFVLLGPsgPGKDYH----EIGRAIATLMSDEVFhdaayladdRDDLLAGIDEfldcsivlppgewdpEIRLEPPAP 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  328 -QRQLL-------TMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIReDIARRFPLYPLDFTDGIigkNKAV 399
Cdd:TIGR00834 296 lQRELLrkryepsTVRPENPTMGGDTEPEDGGSEGPHGDDDPLQRTGRPFGGLIR-DIKRRYPHYLSDFTDAL---NPQC 371
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  400 gkyITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDY 479
Cdd:TIGR00834 372 ---LAAVIFIYFAALSPAITFGGLLGEKTRNMMGVSELLISTAVQGVLFALLAAQPLLVVGFSGPLLVFEEAFFSFCESN 448
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  480 DLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFwkyyyghylDDYHTKRTS 559
Cdd:TIGR00834 449 GLEYLVGRVWIGLWLVLLVLLLVATEGSFLVRYISRFTQEIFSFLISLIFIYETFSKLIKIF---------QEHPLQVFY 519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  560 -SLVSLSGLGASLNASLHTALNASfLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDC 638
Cdd:TIGR00834 520 nTLFCVPPKPQGPSVSALLEKDCS-KLGGTLGGNNCRFQPNTALLSLVLMLGTFFLAMFLRKFKNSRYFPGKARRLIGDF 598
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  639 ALPIAVLAFSLISS-------------HGFREIEMSKFRY--NP--SESPFAMAQIQSLSLRAVsgamglgfLLSMLFFI 701
Cdd:TIGR00834 599 GVPISILIMVLVDIfigdtytqklsvpSGLKVTNPSARGWfiPPlgENRPFPWWMMFAAALPAL--------LVFILIFM 670
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  702 EQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDtIVNVKET 781
Cdd:TIGR00834 671 EQQITTLIVSKKERKLKKGSGFHLDLLLVVGMGGVAALFGLPWLSAATVRSVTHANALTVMSKASAPGEKAQ-IQEVREQ 749
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  782 RLTSLGASVLVGLSLLLLPVPLQwIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTG 861
Cdd:TIGR00834 750 RVTGLLVAVLVGLSILMEPILKR-IPLAVLFGIFLYMGVTSLSGIQLFDRLLLLLMPPKYHPDVPYVRRVKTWRMHLFTA 828
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 291490690  862 LQVLQLLLLCAFGMSSlpyMKMIFPLIMIAMIPIRYILLPRI---IEAKYLDVMDAE 915
Cdd:TIGR00834 829 IQILCLALLWVVKSTP---ASLAFPFVLILTVPLRRLLLPRLfteRELKCLDKEDAK 882
PtsN COG1762
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
249-327 7.55e-05

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 43.69  E-value: 7.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690 249 KALQKRHVCISRLVRPQNWGENSCE-VRFVILVLAPPKmkSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH 327
Cdd:COG1762   71 EGVKKPGIAVARLKEPVDFGAMDGEpVDLVFLLAAPED--DSEEHLKLLAELARLLSDEEFREKLLNAKSPEEILELLKE 148
 
Name Accession Description Interval E-value
HCO3_cotransp pfam00955
HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange ...
368-861 0e+00

HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange CL-/HCO3-. This family also includes cotransporters of Na+/HCO3-.


Pssm-ID: 460009  Cd Length: 497  Bit Score: 571.78  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  368 PFGkGIREDIARRFPLYPLDFTDGIigknkaVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLL 447
Cdd:pfam00955   2 LFG-GLINDIKRRYPHYLSDFTDAL------NLQCLASIIFLYFACLSPAITFGGLLGDATDGYIGVSESILSQAIGGII 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  448 YALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISI 527
Cdd:pfam00955  75 FALFAGQPLTILGSTGPLLVFEKILFKFCKDNGLDYLSFRAWIGLWLAFFLLLLVAFDASFLVRYITRFTEEIFALLISL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  528 TFVLDAVKGTVKIFwKYYYGHYLDDYHTKRTSSLVSLSglGASLNASLHTALNASFLASPTE---------LPSATHSGQ 598
Cdd:pfam00955 155 IFIYEAFKKLIKIF-KKYPLYLNYDCTCVPPSSNNTTN--STLSLSTESSSINWSSLLTNSEctesyggtlVGSGCGYVP 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  599 ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEM----SKFRYNPSESPFAM 674
Cdd:pfam00955 232 DTALLSLILFLGTFWLAYFLKQFKNSPFFPTKVRRLISDFAVPIAILIMVLVDYFLGVYTPKlqvpSGFKPTRPDRGWII 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  675 AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPL 754
Cdd:pfam00955 312 NPFGKNPWWLILAAILPALLVTILIFMDQQITAVIVNRKENKLKKGSGYHLDLFVVAILNGICSLFGLPWMVAATVRSIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  755 HVRALALVEERVENGhIYDTIVNVKETRLTSLGAsVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVAL 834
Cdd:pfam00955 392 HVNSLKVESECVAPG-EKPKILGVREQRVTGLLV-FILIGLSVFMTPVLKLIPMPVLYGVFLYMGVTSLSGIQFFDRILL 469
                         490       500
                  ....*....|....*....|....*..
gi 291490690  835 LLKEQTAYPPTHYIRRVPQRKIHYFTG 861
Cdd:pfam00955 470 LFMPQKHQPDTHYLRHVPLRKVHLFTL 496
ae TIGR00834
anion exchange protein; The Anion Exchanger (AE) Family (TC 2.A.31)Characterized protein ...
274-915 2.53e-89

anion exchange protein; The Anion Exchanger (AE) Family (TC 2.A.31)Characterized protein members of the AE family are found only in animals.They preferentially catalyze anion exchange (antiport) reactions, typically acting as HCO3-:Cl- antiporters, but also transporting a range of other inorganic and organic anions. Additionally, renal Na+:HCO3- cotransporters have been found to be members of the AE family. They catalyze the reabsorption of HCO3- in the renal proximal tubule. [Transport and binding proteins, Anions]


Pssm-ID: 273290 [Multi-domain]  Cd Length: 900  Bit Score: 304.00  E-value: 2.53e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  274 VRFVILVLAP--PKMKSTktamEVARTFATMFSDIAF---------RQKLLETRTE---------------EEFKEALVH 327
Cdd:TIGR00834 220 VRFLFVLLGPsgPGKDYH----EIGRAIATLMSDEVFhdaayladdRDDLLAGIDEfldcsivlppgewdpEIRLEPPAP 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  328 -QRQLL-------TMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIReDIARRFPLYPLDFTDGIigkNKAV 399
Cdd:TIGR00834 296 lQRELLrkryepsTVRPENPTMGGDTEPEDGGSEGPHGDDDPLQRTGRPFGGLIR-DIKRRYPHYLSDFTDAL---NPQC 371
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  400 gkyITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDY 479
Cdd:TIGR00834 372 ---LAAVIFIYFAALSPAITFGGLLGEKTRNMMGVSELLISTAVQGVLFALLAAQPLLVVGFSGPLLVFEEAFFSFCESN 448
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  480 DLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFwkyyyghylDDYHTKRTS 559
Cdd:TIGR00834 449 GLEYLVGRVWIGLWLVLLVLLLVATEGSFLVRYISRFTQEIFSFLISLIFIYETFSKLIKIF---------QEHPLQVFY 519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  560 -SLVSLSGLGASLNASLHTALNASfLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDC 638
Cdd:TIGR00834 520 nTLFCVPPKPQGPSVSALLEKDCS-KLGGTLGGNNCRFQPNTALLSLVLMLGTFFLAMFLRKFKNSRYFPGKARRLIGDF 598
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  639 ALPIAVLAFSLISS-------------HGFREIEMSKFRY--NP--SESPFAMAQIQSLSLRAVsgamglgfLLSMLFFI 701
Cdd:TIGR00834 599 GVPISILIMVLVDIfigdtytqklsvpSGLKVTNPSARGWfiPPlgENRPFPWWMMFAAALPAL--------LVFILIFM 670
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  702 EQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDtIVNVKET 781
Cdd:TIGR00834 671 EQQITTLIVSKKERKLKKGSGFHLDLLLVVGMGGVAALFGLPWLSAATVRSVTHANALTVMSKASAPGEKAQ-IQEVREQ 749
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690  782 RLTSLGASVLVGLSLLLLPVPLQwIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTG 861
Cdd:TIGR00834 750 RVTGLLVAVLVGLSILMEPILKR-IPLAVLFGIFLYMGVTSLSGIQLFDRLLLLLMPPKYHPDVPYVRRVKTWRMHLFTA 828
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 291490690  862 LQVLQLLLLCAFGMSSlpyMKMIFPLIMIAMIPIRYILLPRI---IEAKYLDVMDAE 915
Cdd:TIGR00834 829 IQILCLALLWVVKSTP---ASLAFPFVLILTVPLRRLLLPRLfteRELKCLDKEDAK 882
PtsN COG1762
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
249-327 7.55e-05

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 43.69  E-value: 7.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291490690 249 KALQKRHVCISRLVRPQNWGENSCE-VRFVILVLAPPKmkSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH 327
Cdd:COG1762   71 EGVKKPGIAVARLKEPVDFGAMDGEpVDLVFLLAAPED--DSEEHLKLLAELARLLSDEEFREKLLNAKSPEEILELLKE 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH