|
Name |
Accession |
Description |
Interval |
E-value |
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
19-347 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 524.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAIHVGQDPEQwTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC-------------- 84
Cdd:pfam01053 1 DTLAVHAGQRPDP-QTGAVSVPIYLTSTYVFDFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAAlafssgmaaitaai 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH 145
Cdd:pfam01053 80 lallkagdhivatddlyggTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 146 KHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNR 225
Cdd:pfam01053 160 KHG-ILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 226 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTL 305
Cdd:pfam01053 239 GLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGLEAAKKFLDNLKLFSL 318
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 299473759 306 AESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:pfam01053 319 AVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVG 360
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
16-347 |
4.62e-177 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 497.26 E-value: 4.62e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 16 QHFATQAIHVGQDPEQWTsRAVVPPISLSTTFKQGAPGQ--------HSGFEYSRSGNPTRNCLEKAVAALDGAKYC--- 84
Cdd:COG0626 1 MGPATRAVHAGRDPDPQT-GAVSPPIYLTSTFVFPSAEAlaarfageEGGYIYSRYGNPTRRALEEALAALEGGEAAlaf 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ------------------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKV 134
Cdd:COG0626 80 asgmaaisavllallkagdhvvasddlyggTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 135 IDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAV 214
Cdd:COG0626 160 VDIAAIAAIAHAAG-ALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 215 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAE 294
Cdd:COG0626 239 LSPFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGREAAR 318
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 299473759 295 IFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:COG0626 319 RFLDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVG 371
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
36-347 |
4.63e-173 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 486.32 E-value: 4.63e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 36 AVVPPISLSTTFKQGAP--------GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC----------------------- 84
Cdd:cd00614 2 AVAPPIYQTSTFVFPSPaeaadlfaLREGGYIYSRIGNPTVDALEKKLAALEGGEAAlafssgmaaistvllallkagdh 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ----------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGdIILVV 154
Cdd:cd00614 82 vvasddlyggTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHG-ALLVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 155 DNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRM 234
Cdd:cd00614 161 DNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 235 EKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFES 314
Cdd:cd00614 241 ERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGLEAAKKFLNALKLFSLAVSLGGVES 320
|
330 340 350
....*....|....*....|....*....|...
gi 299473759 315 LAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:cd00614 321 LVEHPASMTHSQLPPEERAAAGITPGLVRLSVG 353
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
13-347 |
4.17e-142 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 408.65 E-value: 4.17e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 13 PHFQHFATQAIHVGQDPEQWTSrAVVPPISLSTTFKQGAPGQ-HSGFEYSRSGNPTRNCLEKAVAALDGAKY-------- 83
Cdd:PRK07811 8 HANQGFATRAIHAGYEPDPATG-AVNPPIYASSTFAQDGVGGlRGGYEYARTGNPTRTALEEQLAALEGGAYgrafssgm 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 84 ----C---------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIE 138
Cdd:PRK07811 87 aatdCllravlrpgdhivipndayggTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLLSITDIA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 139 GCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPI 218
Cdd:PRK07811 167 ALAELAHDAG-AKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGAGAVPGPF 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 219 DCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLK 298
Cdd:PRK07811 246 DAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAGGEEAARDFCA 325
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 299473759 299 NLKLFTLAESLGGFESLAELPAIMTHASVLKNDrdvLGISDTLIRLSVG 347
Cdd:PRK07811 326 RTKVFTLAESLGGVESLIEHPSAMTHASTAGSQ---LEVPDDLVRLSVG 371
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
20-347 |
1.29e-126 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 369.05 E-value: 1.29e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 20 TQAIHVGQDPEQWTSrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDG--AKYC------------- 84
Cdd:PRK07671 5 TKLIHGGIIGDPSTG-AVSVPIYQVSTYKQEAVGKHQGYEYSRTGNPTRAALEELIAVLEGghAGFAfgsgmaaitavmm 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -----------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKH 147
Cdd:PRK07671 84 lfssgdhviltddvyggTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 148 GdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGL 227
Cdd:PRK07671 164 G-LLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 228 KTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIkGTLQHAEIFLKNLKLFTLAE 307
Cdd:PRK07671 243 KTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDV-GSEETANKVLERLQYFTLAE 321
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 299473759 308 SLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK07671 322 SLGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVG 361
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
17-347 |
1.51e-119 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 351.12 E-value: 1.51e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 17 HFATQAIHvGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC------------ 84
Cdd:PRK06176 2 RMQTKLIH-GGISEDTTTGAVSVPIYQTSTYRQDAIGRPKGYEYSRSGNPTRFALEELIADLEGGVKGfafasglagiha 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 --------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIV 144
Cdd:PRK06176 81 vfslfqsgdhvllgddvyggTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 145 HKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN 224
Cdd:PRK06176 161 KDHG-LLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 225 RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQhAEIFLKNLKLFT 304
Cdd:PRK06176 240 RGIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSE-AVAFVESLKLFI 318
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 299473759 305 LAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK06176 319 LGESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVG 361
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
36-347 |
3.10e-106 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 317.13 E-value: 3.10e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 36 AVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKY------------------------------C- 84
Cdd:TIGR02080 21 CVVPPIYLSTTYNFTGFNEPRAYDYSRSGNPTRDLLQQALAELEGGAGavvtntgmsaihlvttallgpddllvaphdCy 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 --TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGdIILVVDNTFMSPY 162
Cdd:TIGR02080 101 ggTYRLLNALAKKGCFRVLFVDQGDEQALRAALAQKPKLVLIETPSNPLLRVVDIAKICHLAKAVG-AVVVVDNTFLSPA 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 163 FQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGM 242
Cdd:TIGR02080 180 LQNPLALGADLVLHSCTKYLNGHSDVIAGAVIAKDPQVAEELAWWANNLGVTGGAFDSYLTLRGLRTLVARMRLQQRNAQ 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 243 AVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIM 322
Cdd:TIGR02080 260 AIVEYLQTQPLVKKIYYPGLPDHPGHEIAARQQKGFGAMLSFELKGGEQTVRRFLGGLSLFTLAESLGGVESLIAHPATM 339
|
330 340
....*....|....*....|....*
gi 299473759 323 THASVLKNDRDVLGISDTLIRLSVG 347
Cdd:TIGR02080 340 THAAMGPEARAEAGISDTLLRLSVG 364
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
18-347 |
1.62e-104 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 313.30 E-value: 1.62e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 18 FATQAIHVGQDPE-QWTSRAVvpPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKY----- 83
Cdd:PRK06234 9 FATKAIHGGHIGDkQFGSLAT--PIYQTSTFifdsaEQGGrrfAGEESGYIYSRLGNPTSTEVENKLALLEGGEAavvaa 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 84 ----------------------------CTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVI 135
Cdd:PRK06234 87 sgmgaissslwsalkagdhvvasdtlygCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 136 DIEGCAHIVHKHG-DIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVsVNCESLHNRLRF--LQNSLG 212
Cdd:PRK06234 167 DIKAISNIAHENNkECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFV-VGKEEFINQVKLfgIKDMTG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 213 AVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQH 292
Cdd:PRK06234 246 SVIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGGVEE 325
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 299473759 293 AEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK06234 326 GKVVMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVG 380
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
16-364 |
1.74e-101 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 305.27 E-value: 1.74e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 16 QHFATQAIHVGQDPEQWTSrAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKY---- 83
Cdd:TIGR01328 2 MTFATRAIHAGYPPKDQFG-ALTPPIYQTSTFvfdscEQGGnrfAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAavat 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 84 -----------------------------CTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKV 134
Cdd:TIGR01328 81 ssgmgaiaatlltilkagdhlisdeclygCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 135 IDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN-RLRFLQNSLGA 213
Cdd:TIGR01328 161 IDMERVCRDAHSQG-VKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQiRMVGIKDMTGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 214 VPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHA 293
Cdd:TIGR01328 240 VISPFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELKGGFAGA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 299473759 294 EIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKA 364
Cdd:TIGR01328 320 KKLLNNLKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQALDA 390
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
19-365 |
3.87e-100 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 301.36 E-value: 3.87e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAIHVGQDPEQWTsrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAK--YC------------ 84
Cdd:TIGR01329 2 STLLVNTDNKNDPYD--ASSMPIYQTATFKQPLAIENGPYDYTRSGNPTRTALESLLAKLDKADraFAfssgmaaldvit 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHK 146
Cdd:TIGR01329 80 rllnngdeiiagddlyggTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 147 HGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRG 226
Cdd:TIGR01329 160 QN-ALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 227 LKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGcTGMVTFYIKGTLQHAEIFLKNLKLFTLA 306
Cdd:TIGR01329 239 IKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKG-AGSVLSFETGSVALSKRLVEATKLFSIT 317
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 299473759 307 ESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 365
Cdd:TIGR01329 318 VSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAFVTA 376
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
18-368 |
7.94e-99 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 299.02 E-value: 7.94e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 18 FATQAIHVGQDPEQwTSRAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKY------ 83
Cdd:PRK07503 10 FSTRAIHHGYDPLD-HGGALVPPVYLTATFafptaEYGAecfAGEEEGHFYSRISNPTLALLEQRMASLEGGEAavalas 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 84 ---------------------------CTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVID 136
Cdd:PRK07503 89 gmgaitatlwtllrpgdevivdqtlygCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVD 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 137 IEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVsVNCESLHNRLRF--LQNSLGAV 214
Cdd:PRK07503 169 IAAVAEIAHGAG-AKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLV-VGGKALADRIRLegLKDMTGAV 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 215 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAE 294
Cdd:PRK07503 247 MSPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKGGIAAGR 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 299473759 295 IFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPP 368
Cdd:PRK07503 327 RFMNALQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALDACAVA 400
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
18-369 |
9.28e-98 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 295.91 E-value: 9.28e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 18 FATQAIH--VGQDPEqwtSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC----------- 84
Cdd:PRK08064 7 IDTLLLHnqYKHDKQ---TGAVNVPIYHASTFHQFDFDTFGKYDYSRSGNPTREALEDIIAELEGGTKGfafasgmaais 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ---------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHI 143
Cdd:PRK08064 84 taflllskgdhvlisedvyggTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGVVKL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 144 VHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLC 223
Cdd:PRK08064 164 AKAIG-CLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCWLV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 224 NRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFyikgTLQHAEI---FLKNL 300
Cdd:PRK08064 243 LRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSF----TLQSEEAvrqFVSHV 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 299473759 301 KLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPS 369
Cdd:PRK08064 319 KLPVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYVEEPV 387
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
13-347 |
6.17e-96 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 292.32 E-value: 6.17e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 13 PHFQHFATQAIHVGQDPEQwTSRAVVPPISLSTTFK-----QGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDG---- 80
Cdd:COG2873 3 EKKYGFETLALHAGQEPDP-TTGARAVPIYQTTSYVfddaeHAAdlfALKEPGNIYTRIMNPTTDVLEKRIAALEGgvaa 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 81 --------------------------AKYC---TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPT 131
Cdd:COG2873 82 latasgqaaitlailnlaeagdhivaSSSLyggTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 132 QKVIDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVsVNC-------------- 197
Cdd:COG2873 162 LDVLDIEAIAEIAHEHG-VPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVI-VDGgnfdwaangkfpel 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 198 ----ESLHN----------------RLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKV 257
Cdd:COG2873 240 tepdPSYHGlvyteafgnaafitkaRVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 258 IYPGLPSHPQHELVKRQCT-GCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLG 336
Cdd:COG2873 319 NYPGLPSHPYHELAQKYLPkGAGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAG 398
|
410
....*....|.
gi 299473759 337 ISDTLIRLSVG 347
Cdd:COG2873 399 VTPDLIRLSVG 409
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
16-347 |
3.76e-94 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 285.83 E-value: 3.76e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 16 QHFATQAIHVGQDPEQWTSrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKY---C-------- 84
Cdd:PRK08247 3 STIETKLAQIGNRSDERTG-TVNPPVYFSTAYRHEGIGESTGFDYSRTGNPTRGVLEQAIADLEGGDQgfaCssgmaaiq 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ---------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHI 143
Cdd:PRK08247 82 lvmslfrsgdelivssdlyggTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAKI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 144 VHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLC 223
Cdd:PRK08247 162 AKKHG-LLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 224 NRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLpshpqhelvkrqctgcTGMVTFyikgTLQHAE---IFLKNL 300
Cdd:PRK08247 241 IRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLYPGR----------------GGMLSF----RLQDEEwvnPFLKSL 300
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 299473759 301 KLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK08247 301 KLITFAESLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVG 347
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
36-347 |
1.36e-92 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 285.00 E-value: 1.36e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 36 AVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAK--YC----------------------------- 84
Cdd:PLN02509 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADraFCftsgmaalsavthlikngeeivagddvyg 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVvDNTFMSPYF 163
Cdd:PLN02509 183 gSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLV-DNSIMSPVL 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 164 QRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMA 243
Cdd:PLN02509 262 SRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARK 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 244 VAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGcTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMT 323
Cdd:PLN02509 342 IAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKG-AGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS 420
|
330 340
....*....|....*....|....
gi 299473759 324 HASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PLN02509 421 HASIPAEVREARGLTEDLVRISAG 444
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
16-363 |
4.43e-91 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 278.65 E-value: 4.43e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 16 QHFATQAIHVGQDPEQWTSrAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKY---- 83
Cdd:PRK06767 4 KHMETALIHHGYTSEEHKG-SLTPPLFQTSTFtfetaQQGEasfAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEalaf 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 84 -----------------------------CTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKV 134
Cdd:PRK06767 83 gsgmaaisatligflkagdhiicsnglygCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTMKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 135 IDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAV 214
Cdd:PRK06767 163 IDLKQVIRVAKRNG-LLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 215 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYpglpshPQHELVKRQCTGCTGMVTFYIKGTLQHAE 294
Cdd:PRK06767 242 MAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY------PEGELASRQMKRGGGVISFSIKGGKEETQ 315
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 299473759 295 IFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALK 363
Cdd:PRK06767 316 AFINDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALK 384
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
19-347 |
1.25e-87 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 269.84 E-value: 1.25e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAIHVGQDPEQwTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAK-----YC--------- 84
Cdd:PRK08861 7 ATIAVRTGIESDS-QYHAVVPPIYLSTNYGFPAFGEVPKYDYTRSGNPNRGLLEQTLSELESGKgavvtNCgtsalnlwv 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH 145
Cdd:PRK08861 86 sallgpddlivaphdcyggTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQKAK 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 146 KHGDIIlVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNR 225
Cdd:PRK08861 166 AVGALV-AVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMTLR 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 226 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTL 305
Cdd:PRK08861 245 GIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKVFVKALALFSL 324
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 299473759 306 AESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK08861 325 AESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVG 366
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
17-347 |
1.67e-86 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 267.63 E-value: 1.67e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 17 HFATQAIHVGQDPEQwTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDG---------------- 80
Cdd:PRK08776 12 SAATAAVRAGIDRDT-AYGAVTPPIVLSSNFSFDGFGNKRQYDYTRSGNPTRDLLGEALAELEGgaggvitatgmgainl 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 81 -----------------AKYCTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHI 143
Cdd:PRK08776 91 vlnallqpgdtlvvphdAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRFVIEA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 144 VHKHGDIIlVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLC 223
Cdd:PRK08776 171 AHKVGALT-VVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDAFLT 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 224 NRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLF 303
Cdd:PRK08776 250 LRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAAVRAFVDGLRYF 329
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 299473759 304 TLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK08776 330 TLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVG 373
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
17-347 |
3.90e-85 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 263.40 E-value: 3.90e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 17 HFATQAIHVGQD--PEQWTSRAVVPpiSLSTTFKQGA------PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC---- 84
Cdd:PRK08133 6 GFDTLAVRAGQLrsPFGEHSEALFL--TSSFVFESAAeaaarfAGEEPGNIYSRFTNPTVTMFQERLAALEGAEACvata 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -----------------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVI 135
Cdd:PRK08133 84 sgmaailavvmallqagdhvvssrslfgsTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTELA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 136 DIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQnSLGAVP 215
Cdd:PRK08133 164 DIAALAEIAHAAG-ALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVFGFLR-TAGPTL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 216 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEI 295
Cdd:PRK08133 242 SPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKGGREAAWR 321
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 299473759 296 FLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK08133 322 VIDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVG 373
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
19-347 |
6.53e-84 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 260.21 E-value: 6.53e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAIHVG-QDPEQWTsrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAK--------------Y 83
Cdd:PRK08045 6 ATIAVRSGlNDDEQYG--CVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAgavltntgmsaihlV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 84 CT-------------------NRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIV 144
Cdd:PRK08045 84 TTvflkpgdllvaphdcyggsYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 145 HKHGDIIlVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN 224
Cdd:PRK08045 164 REAGAVS-VVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 225 RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFT 304
Cdd:PRK08045 243 RGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFT 322
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 299473759 305 LAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK08045 323 LAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTG 365
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
17-347 |
5.65e-82 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 254.36 E-value: 5.65e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 17 HFATQAIHVGQDPEQWTSrAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC------------ 84
Cdd:PRK07269 6 HINTILAQAGIKSDEATG-ALVTPLHFSTTYQHPEFGQSTGFDYTRTKNPTRAKLEETLAAIESADYAlatssgmsaivl 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 --------------------TNRYFRQVASEFglKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIV 144
Cdd:PRK07269 85 afsvfpvgskvvavrdlyggSFRWFNQQEKEG--RFHFTYANTEEELIAAIEEDTDIVYIETPTNPLMVEFDIEKVAKLA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 145 HKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN 224
Cdd:PRK07269 163 HAKG-AKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLLM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 225 RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLpshpqhelvkrqctgcTGMVTFYI--KGTLQHaeiFLKNLKL 302
Cdd:PRK07269 242 RGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYTGK----------------GGMISFKVadETRIPH---ILNSLKV 302
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 299473759 303 FTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK07269 303 FTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIG 347
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
19-347 |
1.05e-81 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 254.60 E-value: 1.05e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAI--HVGQDPeqwtSRAVVPPISLSTTFKQGAPGQHS--GFE--YSRSGNPTRNCLEKAVAALDGAK---------- 82
Cdd:PRK08574 4 GTDAVrgYRGSDP----YGSLQPPIYLTALFRQEGEAYPSdrGFDlkYSREENPTLRPLEEALAKLEGGVdalafnsgma 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 83 ----------------------YCTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGC 140
Cdd:PRK08574 80 aistlffsllkagdrvvlpmeaYGTTLRLLKSLEKFGVKVVLAYPSTEDIIEAIKEGRTKLVFIETMTNPTLKVIDVPEV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 141 AHiVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDC 220
Cdd:PRK08574 160 AK-AAKELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGTIMQPFEA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 221 YLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKR--QCTGCTGMVTFYIKGTLQHAEIFLK 298
Cdd:PRK08574 239 YLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRlfGKDLYGGVVSFRVKGGRDAVLKFLR 318
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 299473759 299 NLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK08574 319 SLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVG 367
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
17-347 |
2.76e-80 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 251.20 E-value: 2.76e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 17 HFATQAIHVGQDpEQWTSRAVVPPISLSTTFK--------QGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC---- 84
Cdd:PRK08249 8 GVGTKAVWAGEK-EYLPYGATQVPVVLSVAYGyddidewyDVALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAAtafs 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -----------------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVI 135
Cdd:PRK08249 87 tgmaaisntlytflkpgdrvvsikdtyggTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 136 DIEGCAHIVHKHGDIIlVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVvMGLVSVNCESLHNRLRFLQNSLGAVP 215
Cdd:PRK08249 167 DIERLAAAAKKVGALV-VVDNTFATPINQNPLALGADLVIHSATKFLSGHADA-LGGVVCGSKELMEQVYHYREINGATM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 216 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEI 295
Cdd:PRK08249 245 DPMSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKGGMDTVKR 324
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 299473759 296 FLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK08249 325 LLPKLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVG 376
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
53-347 |
3.62e-78 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 245.14 E-value: 3.62e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 53 GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC---------------------------------TNRYFRQVASEFGLK 99
Cdd:TIGR01325 41 GELPGFVYSRYGNPTVSVFEERLALLEGAEAAvatasgmaaifaalmallgagdhvvasrslfgsCFVVCSEILPRFGVQ 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 100 ISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSAT 179
Cdd:TIGR01325 121 TVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDIAAVAELAHAAG-AKVVVDNVFATPLLQQPLKLGADVVVYSAT 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 180 KYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIY 259
Cdd:TIGR01325 200 KHIDGQGRVLGGAILGSEEYMDEPVQKLLRHTGPAMSPFNAWVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYY 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 260 PGLPSHPQHELVKRQCTGCTGMVTFYIKGTlQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISD 339
Cdd:TIGR01325 280 PGLPSHPQHELAKRQMSGGGTVVTFDLDCR-QAAFKVLDAMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGD 358
|
....*...
gi 299473759 340 TLIRLSVG 347
Cdd:TIGR01325 359 GLVRLSVG 366
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
15-347 |
3.84e-78 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 245.20 E-value: 3.84e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 15 FQHFATQAIHVGQ--DPEQWTsraVVPPISLSTTF------KQGAPGQHSG--FEYSRSGNPTRNCLEKAVAALDGAKYC 84
Cdd:PRK06434 6 LNGFNTRAVQSGElrDPRFGN---VTTPIFETSTFvypnseKEAYMDSTRGmpYIYTRWGNPTVQAFEEKYAVLENAEHA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ---------------------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITpETKLVWIETPTNPT 131
Cdd:PRK06434 83 lsfssgmgaitsailslikkgkrilsisdlygqTFYFFNKVLKTLGIHVDYIDTDRLNSLDFDPS-NYDLIYAESITNPT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 132 QKVIDIEGCAHIVHKHgdiILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSL 211
Cdd:PRK06434 162 LKVPDIKNVSSFCHEN---DVIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 212 GAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLpshpqhELVKRQCTGCTGMVTFYIKgTLQ 291
Cdd:PRK06434 239 GSNPDPIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELR-SME 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 299473759 292 HAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK06434 312 DVHKFIRNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIG 367
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
17-347 |
6.21e-78 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 245.73 E-value: 6.21e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 17 HFATQAIHVGQDPEQWT-SRAVvpPISLSTTF-----KQGAPG---QHSGFEYSRSGNPTRNCLEKAVAALDGAK----- 82
Cdd:TIGR01326 1 HFETLQLHAGQEPDPTTgSRAV--PIYQTTSYvfdstEHAAALfglQEPGNIYSRLMNPTTDVLEQRIAALEGGVaalav 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 83 ----------------------YCTNRY------FRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKV 134
Cdd:TIGR01326 79 asgqaaityailnlagagdnivSSSYLYggtynlFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 135 IDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV----------------SVNCE 198
Cdd:TIGR01326 159 LDIEAIAEVAHRHG-IPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIvdggkfdwnngrfplfTTPDP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 199 SLHN----------------RLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGL 262
Cdd:TIGR01326 238 SYHGlvftetlgnpafilkaRVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 263 PSHPQHELVKRQCTGCTGMV-TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTL 341
Cdd:TIGR01326 317 ASHPHHALAKKYLPKGFGAVlSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGL 396
|
....*.
gi 299473759 342 IRLSVG 347
Cdd:TIGR01326 397 IRLSVG 402
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
14-347 |
1.32e-71 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 229.56 E-value: 1.32e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 14 HFQHFATQAIHVGQDPEqWTSRAVVPPISLSTTF------------------KQGAPGQHSGFEYSRSGNPTRNCLEKAV 75
Cdd:PRK07049 14 RELHPETQMLNYGYDPE-LSEGAVKPPVFLTSTFvfrsaedgrdffdyvsgrKEPPAGEGAGLVYSRFNHPNSEIVEDRL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 76 AALDGAKYC---------------------------------TNRYFRQVASEFGLK-ISFVDCSKIKLLEAAITP---- 117
Cdd:PRK07049 93 AVYEGAESAalfssgmsaiattllafvrpgdvilhsqplyggTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAEAaaak 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 118 -ETKLVWIETPTNPTQKVIDIEG----CAHIVHKHGDI-ILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMG 191
Cdd:PRK07049 173 gRVSLILIETPANPTNSLVDVAAvrrvADAIEARQGHRpIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAG 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 192 LVSVNcESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGL--PSHPQHE 269
Cdd:PRK07049 253 AVLGR-KALIRQVRALRSAIGTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYLPFldPDSAYGA 331
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 299473759 270 LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK07049 332 VYKRQCTGAGSTFSFDIKGGQAAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIG 409
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
19-347 |
2.55e-70 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 224.71 E-value: 2.55e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAIHVGQDPEqwtSRAVVPPISLSTTFKqgAPGQHSgFEYSRSGNPTRNCLEKAVAALDGAKYC-------------- 84
Cdd:PRK06460 4 ATRTVREDIDEA---TGAITTPIYQTTAYH--YPEGEK-YRYSREANPTVLELTKKIVELENAEMGvafssgmgaistta 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH 145
Cdd:PRK06460 78 lallkpgnsvlvhrdmfgrSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 146 KHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCEsLHNRLRFLQNSLGAVPSPIDCYLCNR 225
Cdd:PRK06460 158 ENG-SILIVDATFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGK-LLNVIDQMRRTLGTSLDPHAAYLTLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 226 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTL 305
Cdd:PRK06460 236 GIKTLKIRMDVINRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGGQESALKVMKSLKLIIP 315
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 299473759 306 AESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK06460 316 AQTLGGVNSVISHPATMSHRTLSLEERKIVGITDSLLRLSVG 357
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
53-365 |
1.15e-68 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 221.17 E-value: 1.15e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 53 GQHSGFEYSRSGNPTRNCLEKAVAALDGAK--------------------------------YCTNRYFRQ-VASEFGLK 99
Cdd:PRK07504 52 GEDPGFIYSRYSNPTVDMFEKRMCALEGAEdaratasgmaavtaailcqvkagdhvvaaralFGSCRYVVEtLLPRYGIE 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 100 ISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSAT 179
Cdd:PRK07504 132 STLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVIDIAAVAKIANQAG-AKLVVDNVFATPLFQKPLELGAHIVVYSAT 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 180 KYMNGHSDVVMGLV-SVNC---ESLHNRLRFLQNSLgavpSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVE 255
Cdd:PRK07504 211 KHIDGQGRCLGGVVlSDKAwieEHLQDYFRHTGPSL----SPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVA 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 256 KVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVL 335
Cdd:PRK07504 287 RVIYPGRADHPQADIIAKQMTGGSTLVAFELKGGKEAAFRFLNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAEL 366
|
330 340 350
....*....|....*....|....*....|
gi 299473759 336 GISDTLIRLSVGLEDEEDLLEDLDQALKAA 365
Cdd:PRK07504 367 GISEGFLRLSAGLEDTDDLIEDLAAALKKV 396
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
20-365 |
1.94e-67 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 218.94 E-value: 1.94e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 20 TQAIHVGQDPEQWT-SRAVvpPISLSTT--FKQGAPG------QHSGFEYSRSGNPTRNCLEKAVAALDGAKYC------ 84
Cdd:PRK08248 11 TLAIHAGQEIDPTTgSRAV--PIYQTTSygFRDSEHAanlfslKEFGNIYTRIMNPTTDVFEKRIAALEGGIGAlavssg 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ---------------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDI 137
Cdd:PRK08248 89 qaaitysilniasagdeivsssslyggTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPKGDVLDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 138 EGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVS----------------------- 194
Cdd:PRK08248 169 EAVAAIAHEHG-IPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwkgsgkfpgltepdpsy 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 195 ---VNCESL-------HNRLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPS 264
Cdd:PRK08248 248 hglVYTDAVgeaayitKARVQLLRD-LGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPGLPS 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 265 HPQHELVKRQC-TGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIR 343
Cdd:PRK08248 327 HPSYELAKKYLpKGQGAILTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLVR 406
|
410 420
....*....|....*....|..
gi 299473759 344 LSVGLEDEEDLLEDLDQALKAA 365
Cdd:PRK08248 407 LSVGTEAIDDILDDLRQAIRQS 428
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
18-365 |
2.65e-64 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 210.75 E-value: 2.65e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 18 FATQAIHVGQDPEQWT-SRAVvpPISLSTTF-----KQGAP---GQHSGFEYSRSGNPTRNCLEKAVAALDGA--KYCT- 85
Cdd:PRK08134 9 FDTLALHAGAAPDPATgARAV--PIHLTTSFvfrdsDHAAAlfnLERAGHVYSRISNPTVAVLEERVAALEGGvgAIATa 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 86 --------------NRYFRQVAS----------------EFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVI 135
Cdd:PRK08134 87 sgqaalhlaiatlmGAGSHIVASsalyggshnllhytlrRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 136 DIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV----------SVNCESL----- 200
Cdd:PRK08134 167 DIPTVAAIAHEAG-VPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLvdggrfdweaSGKFPELtepya 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 201 --HNR------------LRFLQNSL---GAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLP 263
Cdd:PRK08134 246 gfHGMvfaeestvaaflLRARREGLrdfGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 264 SHPQHELVKRQC-TGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLI 342
Cdd:PRK08134 326 SHPDHALAKRLLpRGAGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTI 405
|
410 420
....*....|....*....|...
gi 299473759 343 RLSVGLEDEEDLLEDLDQALKAA 365
Cdd:PRK08134 406 RLSIGLEDADDLIDDLKRALKAA 428
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
19-347 |
5.15e-62 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 202.92 E-value: 5.15e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAIH-VGQDPEQWTSraVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAK--------------- 82
Cdd:PRK07582 5 GTRSVHaGGPEAVPGEP--VLPGPVFAAPYHLSPGEPTGPDTYGRASNPTWRALEAALGELEGAEalvfpsgmaaitavl 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 83 -----------------YCTNRYFRQVASEFGLKISFVDCSKIklLEAAITPeTKLVWIETPTNPTQKVIDIEGCAHIVH 145
Cdd:PRK07582 83 rallrpgdtvvvpadgyYQVRALAREYLAPLGVTVREAPTAGM--AEAALAG-ADLVLAETPSNPGLDVCDLAALAAAAH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 146 KHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNR 225
Cdd:PRK07582 160 AAG-ALLVVDNTTATPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 226 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIkGTLQHAEIFLKNLKLFTL 305
Cdd:PRK07582 239 SLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFEL-ADAAAAERFVAASRLVVA 317
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 299473759 306 AESLGGFESLAELPAIMTHAsvlkndrdvlgISDTLIRLSVG 347
Cdd:PRK07582 318 ATSFGGVHTSADRRARWGDA-----------VPEGFVRLSCG 348
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
17-347 |
1.74e-59 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 198.44 E-value: 1.74e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 17 HFATQAIHVGQDPEQWT-SRAVvpPI--SLSTTFKQGAPGQ------HSGFEYSRSGNPTRNCLEKAVAALDGAKYC--- 84
Cdd:PRK07812 13 SFETKQIHAGQTPDPATnARAL--PIyqTTSYTFDDTDHAAalfglaEPGNIYTRIMNPTQDVVEQRIAALEGGVAAlll 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ------------------------------TNRYFRQVASEFGLKISFV-DCSKIKLLEAAITPETKLVWIETPTNPTQK 133
Cdd:PRK07812 91 asgqaaetfailnlagagdhivssprlyggTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETISNPQID 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 134 VIDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV----------------SVNC 197
Cdd:PRK07812 171 VLDIPGVAEVAHEAG-VPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIvdggtfdwtqgrfpgfTTPD 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 198 ESLHN---------------RLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGL 262
Cdd:PRK07812 250 PSYHGvvfaelgppayalkaRVQLLRD-LGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 263 PSHPQHELVKRQCTGCTG-MVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTL 341
Cdd:PRK07812 329 PSSPWYERAKRLAPKGTGaVLSFELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGL 408
|
....*.
gi 299473759 342 IRLSVG 347
Cdd:PRK07812 409 VRLAVG 414
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
20-365 |
2.93e-59 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 197.43 E-value: 2.93e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 20 TQAIHVGQDPEQwTSRAVVPPISLSTTF-----KQGAPG---QHSGFEYSRSGNPTRNCLEKAVAALDG----------- 80
Cdd:PRK06084 5 TLAIHAGYSPDP-TTKAVAVPIYQTTSYafddtQHGADLfdlKVPGNIYTRIMNPTNDVLEQRVAALEGgvgalavasgm 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 81 --------------------AKYCTNRY--FRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIE 138
Cdd:PRK06084 84 aaityaiqtiaeagdnivsvAKLYGGTYnlLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIIDIQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 139 GCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV------------------SVNCESL 200
Cdd:PRK06084 164 ALADAAHRHG-VPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVvdsgkfpwaehkerfallNTPDPSY 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 201 HN--------------RLRFLQ-NSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSH 265
Cdd:PRK06084 243 HGvtyteafgpaafigRCRVVPlRNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPDH 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 266 PQHELVKRQCTGC-TGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVlkNDRDVL--GISDTLI 342
Cdd:PRK06084 323 PEHELARRYMGGKpASILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQL--NDEELEkaGVSRDMV 400
|
410 420
....*....|....*....|...
gi 299473759 343 RLSVGLEDEEDLLEDLDQALKAA 365
Cdd:PRK06084 401 RLSIGIEHIDDIIADLAQALDAS 423
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
20-347 |
4.47e-59 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 196.18 E-value: 4.47e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 20 TQAIHVGQDPEQWTSrAVVPPISLSTT--FKQGAP--GQHSGFEYSRSGNPTRNCLEKAVAALDGAK------------- 82
Cdd:PRK05967 15 TRLAHDGNDPGDYHG-FVNPPVVHASTvlFPDAETmaTRGQKYTYGTRGTPTTDALCKAIDALEGSAgtilvpsglaavt 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 83 -------------------YCTNRYF-RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAH 142
Cdd:PRK05967 94 vpflgflspgdhalivdsvYYPTRHFcDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAIAE 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 143 IVHKHGDIILVvDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNcESLHNRLRFLQNSLGAVPSPIDCYL 222
Cdd:PRK05967 174 AAHRHGAIVMM-DNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSAN-EKCWPQLLEAHGTLGLCAGPDDTYQ 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 223 CNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTL----QHAEIFLK 298
Cdd:PRK05967 252 ILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPekgkAKAHAFLD 331
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 299473759 299 NLKLFTLAESLGGFESLAeLPAIMTHASVLKNDRDvlgisDTLIRLSVG 347
Cdd:PRK05967 332 ALEIFGLGYSWGGYESLA-LHVKLGDRTVAKAPYA-----GPVIRLQIG 374
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
18-365 |
6.95e-58 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 194.16 E-value: 6.95e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 18 FATQAIHVGQDPEQwTSRAVVPPISLSTTF-----KQGAP--G-QHSGFEYSRSGNPTRNCLEKAVAALDG--------- 80
Cdd:PRK05994 8 FATLAVHAGAQPDP-TTGARATPIYQTTSFvfndaDHAASlfGlQAFGNIYTRITNPTNAVLEERVAALEGgtaalavas 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 81 ---AKYCT----------------------NRyFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVI 135
Cdd:PRK05994 87 ghaAQFLVfhtllqpgdefiaarklyggsiNQ-FGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 136 DIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVsVNC------------------ 197
Cdd:PRK05994 166 DIAAIAEVAHRAG-LPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGII-VDGgtfdwsksgkypmlsepr 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 198 ---------ESLHN-------RLRFLQNsLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPG 261
Cdd:PRK05994 244 peyhglvlhETFGNfafaiaaRVLGLRD-LGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 262 LPSHPQHELVKRQCTGCTGMV-TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDT 340
Cdd:PRK05994 323 LPDDPYHALAQKYSPKGAGAVfTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPD 402
|
410 420
....*....|....*....|....*
gi 299473759 341 LIRLSVGLEDEEDLLEDLDQALKAA 365
Cdd:PRK05994 403 VVRLSIGIEDVDDIIADLEQALAKA 427
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
12-347 |
1.52e-55 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 187.25 E-value: 1.52e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 12 LPHFQHFATQAIHVGQDPEQWTSRAvvPPISLSTTF--------KQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKY 83
Cdd:PRK07810 10 LPDGVSQATIGVRGGLLRSGFEETA--EALYLTSGYvyesaaaaEAAFTGELDRFVYSRYGNPTVSMFEERLRLIEGAEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 84 C------TNRYF-----------RQVAS----------------EFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNP 130
Cdd:PRK07810 88 CfatasgMSAVFtalgallgagdRLVAArslfgscfvvcneilpRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 131 TQKVIDIEGCAHIVHKHGDIIlVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNS 210
Cdd:PRK07810 168 MQSLVDIAAVSELAHAAGAKV-VLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRH 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 211 LGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTL 290
Cdd:PRK07810 247 TGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPE 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 299473759 291 ----QHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PRK07810 327 daakKRAFEVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVG 387
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
20-347 |
2.36e-55 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 185.85 E-value: 2.36e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 20 TQAIHVGQDPEQWtSRAVVPPISLSTT--FKQGAP--GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCT---------- 85
Cdd:TIGR01324 1 TRLIHSGRQPRFS-QGSVNPPLQRASTvlFDSHAAqrRAKGELTYGRRGTLTHFALQDAMCELEGGAGCYlypsglaavt 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 86 ----------------------NRYF-RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAH 142
Cdd:TIGR01324 80 nsilafvkagdhvlmvdsayepTRYFcDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAIAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 143 IVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVnCESLHNRLRFLQNSLGAVPSPIDCYL 222
Cdd:TIGR01324 160 AARNPG-IVIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVVA-NARTWDQLREHSYLMGQMVDADDAYT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 223 CNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHA-EIFLKNLK 301
Cdd:TIGR01324 238 TLRGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLQRLTQKQvHAFLDHLQ 317
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 299473759 302 LFTLAESLGGFESLAeLP--AIMTHASVLKNDrdvlgISDTLIRLSVG 347
Cdd:TIGR01324 318 LFGLGYSWGGYESLA-LCnqPELGHRPNIKRN-----LEGPLIRVHIG 359
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
19-347 |
2.91e-55 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 186.09 E-value: 2.91e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAIHVGQDpEQWTSRAVVPPISLSTTF--------KQGAPGQHSG-FEYSRSGNPTRNCLEKAVAALDGAKYC----- 84
Cdd:PRK09028 6 ATKIVSAGRD-KKWTKGVINPPVFRASTVvfdtvaemRHAAKNRANGeMFYGRRGTPTHFAFQAAIVELEGGAGTalyps 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ----------------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVID 136
Cdd:PRK09028 85 gaaaisnallsflkagdhllmvdscyepTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEVQD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 137 IEGCAHIVHKHgDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNcESLHNRLRFLQNSLGAVPS 216
Cdd:PRK09028 165 VPTLSRIAHEH-DIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLGTATAN-EKHWDQLREHSYLMGQCTS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 217 PIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIK-GTLQHAEI 295
Cdd:PRK09028 243 PDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqGDPKAVTA 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 299473759 296 FLKNLKLFTLAESLGGFESLaelpaIMTHASVlKNDRDVL--GISDTLIRLSVG 347
Cdd:PRK09028 323 LVEGMQHFKMGFSWGGFESL-----ILGVFGI-NKLRTATnwDFSKPLIRLHIG 370
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
8-365 |
3.09e-54 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 183.36 E-value: 3.09e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 8 SQGFLPHfqhfaTQAIHVGQDPEQWTSRAVVPPI---SLsTTFKQGAP------GQHSGFEYSRSGNPTRNCLEKAVAAL 78
Cdd:PRK05968 2 NDGLDPF-----DLAALITAHDEGNAFDAVVPPIfqtSL-FTFDSYDEmedvyaGEKVRPIYSRGDNPTVRAFEEMLAKL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 79 DGA------------------------------KYCTN---RYFRQVASEFGLKISFVDCSKIKLLEAAItPETKLVWIE 125
Cdd:PRK05968 76 EGAedargfasgmaaisstvlsfvepgdrivavRHVYPdafRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 126 TPTNPTQKVIDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVsVNCESLHNRLR 205
Cdd:PRK05968 155 SPTSWVFELQDVAALAALAKRHG-VVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVV-AGSKEHIARIN 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 206 FLQNS-LGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELvkrqcTGCTGMVTF 284
Cdd:PRK05968 233 AEAYPyLGAKLSPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPPAGL-----SGTSGLFSF 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 285 YIKGTLQHAEiFLKNLKLFTLAESLGGFESLAeLPA-IMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALK 363
Cdd:PRK05968 308 IFREGIDVRA-FADALKLFRLGVSWGGHESLV-VPAeVVLQQKAQPNSAARFGVSPRSVRLHVGLEGTEALWADLEQALA 385
|
..
gi 299473759 364 AA 365
Cdd:PRK05968 386 AA 387
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
36-365 |
3.73e-52 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 178.34 E-value: 3.73e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 36 AVVPPISLSTTFK-----------QGAPGqhsGFEYSRSGNPTRNCLEKAVAALDG--AKYC------------------ 84
Cdd:PRK05939 9 AVHKPIHTSVTYGyedardlidvfQGKKP---GFTYARQGTPTTAALEAKITKMEGgvGTVCfatgmaaiaavfltllra 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -------------TNRYFRQVAsEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGdII 151
Cdd:PRK05939 86 gdhlvssqflfgnTNSLFGTLR-GLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERG-LL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 152 LVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVS----------VNCESLHNR---------------LRf 206
Cdd:PRK05939 164 YVVDNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTdtglfdwsayPNIFPAYRKgdpqqwgltqirkkgLR- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 207 lqnSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYI 286
Cdd:PRK05939 243 ---DMGATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFEL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 287 KGTLQHAEiFLKNLKLFTLAESLGGFESLAeLPAIMT-HASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 365
Cdd:PRK05939 320 ADGIDCFD-FLNRLKLVIKATHLGDTRTLV-IPVAPTiYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
17-347 |
4.09e-51 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 175.30 E-value: 4.09e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 17 HFATQAIHVGQD-PEQWTSraVVPPISLSTT--FKQGAP------GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC--- 84
Cdd:PRK07050 9 ALQTRIVQPDDQiPPGFRS--FVTPVARASTvvFPDLATmraldwRQDVQWRYGLHATPTSLALAQRLAEIEGGRHAllq 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 -------TNRYFRQV-----------------------ASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKV 134
Cdd:PRK07050 87 psglaaiSLVYFGLVkagddvlipdnaygpnrdhgewlARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 135 IDIEGCAHIVHKHGdIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAV 214
Cdd:PRK07050 167 PDVPAITAAARARG-VVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMRLGIG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 215 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGM--VTFYIKGTLQH 292
Cdd:PRK07050 246 VSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLfsVVFDERYSPAQ 325
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 299473759 293 AEIFLKNLKLFTLAESLGGFESLAeLPAIMTHASVLKNDRDvlgisDTLIRLSVG 347
Cdd:PRK07050 326 VDAFVEALELFAIGWSWGGACSLA-MPYDVASMRTAKWPHR-----GTLVRLYIG 374
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
16-347 |
2.16e-44 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 157.56 E-value: 2.16e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 16 QHFATQAIHVGQDPeQWTSRAVVPPI--SLSTTF------KQGAPGQHSG--FeYSRSGNPTRNCLEKAVAALDGAKYC- 84
Cdd:PRK08114 4 KKLDTQLVNAGRSK-KYTQGSVNSVIqrASSLVFdsveakKHATRNRANGelF-YGRRGTLTHFSLQEAMCELEGGAGCa 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 --------------------------------TNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQ 132
Cdd:PRK08114 82 lypcgaaavanailafveqgdhvlmtgtayepTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 133 KVIDIEGCAHIVH-KHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNcESLHNRLRflQNS- 210
Cdd:PRK08114 162 EVHDVPAIVAAVRsVNPDAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIGTAVAN-ARCWEQLR--ENSy 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 211 -LGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGT 289
Cdd:PRK08114 239 lMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKK 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 299473759 290 LQHAEI--FLKNLKLFTLAESLGGFESL------AELPAIMTHASVlkndrdvlGISDTLIRLSVG 347
Cdd:PRK08114 319 LTDEQLanYLDNFSLFSMAYSWGGFESLilanqpEEIAAIRPAGEV--------DFTGTLIRLHIG 376
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
36-347 |
5.28e-43 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 154.54 E-value: 5.28e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 36 AVVPPISLSTTFKqGAPGQHSGFE-YSRSGNPTRNCLEKAVAALDG--AKYCT-------NRYFRQ--------VASE-- 95
Cdd:PLN02242 46 TVMEPDTMRRMFS-GELGPDRDFYiYSRHFNPTVLNLGRQMAALEGteAAYCTasgmsaiSSVLLQlcssgghvVASNtl 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 96 ---------------FGLKISFVDCSKIKLLEAAITP-ETKLVWIETPTNPTQKVIDIEGCAHIVHKHGdIILVVDNTFm 159
Cdd:PLN02242 125 yggthallahflprkCNITTTFVDITDLEAVKKAVVPgKTKVLYFESISNPTLTVADIPELARIAHEKG-VTVVVDNTF- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 160 SPYFQRPLALGADISMYSATKYMNGHSDVVMGLVsvnC--ESLHNRLRFLQNS----LGAVPSPIDCYLCNRGLKTLHVR 233
Cdd:PLN02242 203 APMVLSPARLGADVVVHSISKFISGGADIIAGAV---CgpAELVNSMMDLHHGalmlLGPTMNPKVAFELSERLPHLSLR 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 234 MEKHFKNGMAVAQFLESNPWveKVIYPGLPSHPQHELVKRQ---CTGCTGMVTFYIkGTLQHAEIFLKNLKLFT----LA 306
Cdd:PLN02242 280 MKEHCRRAMEYAKRMKELGL--KVIYPGLEDHPQHALLKSMankGYGFGGLLCLDM-DTEERANRLMRYLQNSTqfgfMA 356
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 299473759 307 ESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 347
Cdd:PLN02242 357 VSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVG 397
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
18-347 |
6.68e-43 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 154.64 E-value: 6.68e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 18 FATQAIHVGQDPEQWTSRAVVPpISLSTTF--------KQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYC----- 84
Cdd:PRK05613 14 FETRSIHAGQSVDSDTSARNLP-IYQTTSYvfdsaehaKQRFALEDLGPIYSRLTNPTVEALENRIASLEGGVHAvafas 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 85 ----------------------------TNRYFRQVASEFGLKISFV-DCSKIKLLEAAITPETKLVWIETPTNPTQKVI 135
Cdd:PRK05613 93 gqaaetaailnlagagdhivtsprlyggTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFGETFANPQADVL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 136 DIEGCAHIVHKHgDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVS--------------------V 195
Cdd:PRK05613 173 DIPAVAEVAHRN-QVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdggkfdwtverdgkpvfpyfV 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 196 NCESLHNRLRF---------------LQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYP 260
Cdd:PRK05613 252 TPDPAYHGLKYadlgapafglkaragLLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNFA 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 261 GLPSHPQHELVKRQCTGCTGMV-TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISD 339
Cdd:PRK05613 332 GLKDSPWYATKEKLGLKYTGSVlSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGITQ 411
|
....*...
gi 299473759 340 TLIRLSVG 347
Cdd:PRK05613 412 ATVRLSVG 419
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
19-347 |
7.02e-36 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 135.57 E-value: 7.02e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 19 ATQAIHVGQDPEQWTSRavVPPISLSTTFKQGAPG--------QHSGFEYSRSGNPTRNCLEKAVAALDGA--------- 81
Cdd:PRK06702 8 GTICVQGGYTPKNGEPR--VLPLYQSTTYKYDTSDdlaalfnlEAEGYIYTRIGNPTLAAFEQKLAELEGGvgavatasg 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 82 ---------KYCTN---------------RYFRQVASEFGLKISFVDCS-KIKLLEAAITPETKLVWIETPTNPTQKVID 136
Cdd:PRK06702 86 qaaimlavlNICSSgdhllcsstvyggtfNLFGVSLRKLGIDVTFFNPNlTADEIVALANDKTKLVYAESLGNPAMNVLN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 137 IEGCAHIVhKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVS---------------VNCESLH 201
Cdd:PRK06702 166 FKEFSDAA-KELEVPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdggnfdwtngkypelVEPDPSY 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 202 NRLRFLQN----------------SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSH 265
Cdd:PRK06702 245 HGVSYVQNfgaaayivkarvqllrDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSN 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 266 PQHELVKRQCT-GCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRL 344
Cdd:PRK06702 325 ENYSLAQKYLKkGASGVLTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRL 404
|
...
gi 299473759 345 SVG 347
Cdd:PRK06702 405 SVG 407
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
109-184 |
3.91e-07 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 49.69 E-value: 3.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 109 KLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGdIILVVDNTFMSPY----FQRPLALGADISMYSATKYMNG 184
Cdd:cd01494 83 ILEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYG-ILLLVDAASAGGAspapGVLIPEGGADVVTFSLHKNLGG 161
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
89-283 |
4.79e-07 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 51.19 E-value: 4.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 89 FRQVASEFGLKISFVDCSK-------IKLLEAAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHgDIILVVDNT- 157
Cdd:cd00609 96 YEAAARLAGAEVVPVPLDEeggflldLELLEAAKTPKTKLLYLNNPNNPTGAVLSeeeLEELAELAKKH-GILIISDEAy 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 158 --FMSPYFQRPLALGAD-----ISMYSATKYMNghsdvVMGL----VSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRG 226
Cdd:cd00609 175 aeLVYDGEPPPALALLDayervIVLRSFSKTFG-----LPGLrigyLIAPPEELLERLKKLLPYTTSGPSTLSQAAAAAA 249
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 299473759 227 LKTLHVRMEKHF----KNGMAVAQFLESNPWVEKV-------IYPGLPSHPQHELVKRQCTGCTGMVT 283
Cdd:cd00609 250 LDDGEEHLEELReryrRRRDALLEALKELGPLVVVkpsggffLWLDLPEGDDEEFLERLLLEAGVVVR 317
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
111-156 |
2.99e-05 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 45.51 E-value: 2.99e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 299473759 111 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHgDIILVVDN 156
Cdd:COG0436 156 LEAAITPRTKAIVLNSPNNPTGAVYsreELEALAELAREH-DLLVISDE 203
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
95-155 |
5.21e-04 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 41.65 E-value: 5.21e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 299473759 95 EFGLKISFVDcskiklLEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHgDIILVVD 155
Cdd:PRK05764 147 ENGFKLTVEQ------LEAAITPKTKALILNSPSNPTGAVYspeELEAIADVAVEH-DIWVLSD 203
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
111-155 |
1.05e-03 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 40.87 E-value: 1.05e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 299473759 111 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHgDIILVVD 155
Cdd:PRK07682 147 IEAAITAKTKAILLCSPNNPTGAVLnksELEEIAVIVEKH-DLIVLSD 193
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
111-159 |
2.48e-03 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 39.34 E-value: 2.48e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 299473759 111 LEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHG-DIILVVDNTFM 159
Cdd:COG0079 129 LLAAITERTDLVFLCNPNNPTGTLLPREELEALLEALPaDGLVVVDEAYA 178
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
111-131 |
3.38e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 39.16 E-value: 3.38e-03
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
108-166 |
3.74e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 38.93 E-value: 3.74e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 299473759 108 IKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHI--VHKHGDIILVVDNTFMSPYFQRP 166
Cdd:PRK06348 152 VKKLEALITSKTKAIILNSPNNPTGAVFSKETLEEIakIAIEYDLFIISDEVYDGFSFYED 212
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
97-155 |
3.90e-03 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 38.83 E-value: 3.90e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 299473759 97 GLKISFVDCSK-------IKLLEAAITPETKLVWIETPTNPTQKVIDIEG---CAHIVHKHGdIILVVD 155
Cdd:pfam00155 108 GGEVVRYPLYDsndfhldFDALEAALKEKPKVVLHTSPHNPTGTVATLEElekLLDLAKEHN-ILLLVD 175
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
108-184 |
4.18e-03 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 38.77 E-value: 4.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299473759 108 IKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGdIILVVD--NTFMSpyfqRPL---ALGADISMYSATKyM 182
Cdd:pfam00266 129 LDELEKLITPKTKLVAITHVSNVTGTIQPVPEIGKLAHQYG-ALVLVDaaQAIGH----RPIdvqKLGVDFLAFSGHK-L 202
|
..
gi 299473759 183 NG 184
Cdd:pfam00266 203 YG 204
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
103-158 |
4.69e-03 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 38.56 E-value: 4.69e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 299473759 103 VDCSK---IKL----LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTF 158
Cdd:PRK06107 144 VACPEeqgFKLtpeaLEAAITPRTRWLILNAPSNPTGAVYsraELRALADVLLRHPHVLVLTDDIY 209
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
111-155 |
6.06e-03 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 38.42 E-value: 6.06e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 299473759 111 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHgDIILVVD 155
Cdd:PRK08912 152 LAAAFSPRTKAVLLNNPLNPAGKVFpreELALLAEFCQRH-DAVAICD 198
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
111-155 |
7.46e-03 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 37.97 E-value: 7.46e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 299473759 111 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHgDIILVVD 155
Cdd:PRK09082 156 FAAAISPRTRLIILNTPHNPSGTVWsaaDMRALWQLIAGT-DIYVLSD 202
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
113-158 |
9.25e-03 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 37.84 E-value: 9.25e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 299473759 113 AAITPETKLVWIETPTNPTQKVI---DIEGCAHIVhKHGDIILVVDNTF 158
Cdd:PRK12414 157 AAITPRTRMIIVNTPHNPSATVFsaaDLARLAQLT-RNTDIVILSDEVY 204
|
|
| |
